Amino acid dipepetide frequency for Beihai picorna-like virus 77

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.741AlaAla: 4.741 ± 0.132
0.729AlaCys: 0.729 ± 0.396
2.553AlaAsp: 2.553 ± 1.32
1.459AlaGlu: 1.459 ± 0.792
3.647AlaPhe: 3.647 ± 0.726
4.012AlaGly: 4.012 ± 0.528
1.823AlaHis: 1.823 ± 0.313
6.2AlaIle: 6.2 ± 0.693
5.106AlaLys: 5.106 ± 0.742
6.565AlaLeu: 6.565 ± 0.181
2.553AlaMet: 2.553 ± 0.644
5.835AlaAsn: 5.835 ± 0.891
3.647AlaPro: 3.647 ± 2.756
1.459AlaGln: 1.459 ± 0.561
4.012AlaArg: 4.012 ± 1.502
3.647AlaSer: 3.647 ± 2.079
5.835AlaThr: 5.835 ± 1.568
2.188AlaVal: 2.188 ± 0.842
1.094AlaTrp: 1.094 ± 0.083
1.459AlaTyr: 1.459 ± 0.792
0.0AlaXaa: 0.0 ± 0.0
Cys
0.729CysAla: 0.729 ± 0.396
0.365CysCys: 0.365 ± 0.198
2.553CysAsp: 2.553 ± 1.386
1.094CysGlu: 1.094 ± 0.594
0.729CysPhe: 0.729 ± 0.396
0.729CysGly: 0.729 ± 0.396
0.0CysHis: 0.0 ± 0.0
0.729CysIle: 0.729 ± 0.281
0.729CysLys: 0.729 ± 0.396
1.094CysLeu: 1.094 ± 0.594
0.365CysMet: 0.365 ± 0.198
0.365CysAsn: 0.365 ± 0.198
0.0CysPro: 0.0 ± 0.0
0.729CysGln: 0.729 ± 0.281
0.729CysArg: 0.729 ± 0.396
1.459CysSer: 1.459 ± 0.115
1.459CysThr: 1.459 ± 0.792
0.729CysVal: 0.729 ± 0.281
0.0CysTrp: 0.0 ± 0.0
0.365CysTyr: 0.365 ± 0.198
0.0CysXaa: 0.0 ± 0.0
Asp
4.012AspAla: 4.012 ± 0.148
0.729AspCys: 0.729 ± 0.396
5.106AspAsp: 5.106 ± 0.742
4.012AspGlu: 4.012 ± 1.502
2.188AspPhe: 2.188 ± 0.511
2.553AspGly: 2.553 ± 1.32
1.823AspHis: 1.823 ± 1.04
3.647AspIle: 3.647 ± 0.05
4.741AspLys: 4.741 ± 0.809
4.741AspLeu: 4.741 ± 1.898
1.459AspMet: 1.459 ± 0.115
4.741AspAsn: 4.741 ± 1.898
2.188AspPro: 2.188 ± 0.165
1.459AspGln: 1.459 ± 1.238
2.188AspArg: 2.188 ± 0.511
2.188AspSer: 2.188 ± 0.165
3.282AspThr: 3.282 ± 1.106
4.012AspVal: 4.012 ± 0.528
1.094AspTrp: 1.094 ± 0.594
2.918AspTyr: 2.918 ± 0.446
0.0AspXaa: 0.0 ± 0.0
Glu
4.741GluAla: 4.741 ± 1.485
1.823GluCys: 1.823 ± 0.99
2.918GluAsp: 2.918 ± 0.908
4.012GluGlu: 4.012 ± 1.502
1.823GluPhe: 1.823 ± 0.363
4.012GluGly: 4.012 ± 0.528
1.094GluHis: 1.094 ± 0.594
4.012GluIle: 4.012 ± 1.502
3.647GluLys: 3.647 ± 1.98
5.47GluLeu: 5.47 ± 0.94
1.823GluMet: 1.823 ± 0.313
2.553GluAsn: 2.553 ± 1.386
2.553GluPro: 2.553 ± 0.71
2.188GluGln: 2.188 ± 0.165
2.188GluArg: 2.188 ± 1.188
1.094GluSer: 1.094 ± 0.594
3.282GluThr: 3.282 ± 0.248
1.459GluVal: 1.459 ± 1.238
0.365GluTrp: 0.365 ± 0.198
3.647GluTyr: 3.647 ± 0.726
0.0GluXaa: 0.0 ± 0.0
Phe
3.647PheAla: 3.647 ± 0.05
1.094PheCys: 1.094 ± 0.083
3.647PheAsp: 3.647 ± 0.627
1.823PheGlu: 1.823 ± 0.313
1.823PhePhe: 1.823 ± 0.99
2.188PheGly: 2.188 ± 0.842
1.823PheHis: 1.823 ± 0.363
3.647PheIle: 3.647 ± 0.627
4.012PheLys: 4.012 ± 1.205
5.835PheLeu: 5.835 ± 1.568
0.0PheMet: 0.0 ± 0.0
2.553PheAsn: 2.553 ± 0.71
1.459PhePro: 1.459 ± 0.561
0.729PheGln: 0.729 ± 0.396
1.823PheArg: 1.823 ± 1.04
1.459PheSer: 1.459 ± 1.238
4.012PheThr: 4.012 ± 0.825
3.282PheVal: 3.282 ± 0.429
0.365PheTrp: 0.365 ± 0.198
1.823PheTyr: 1.823 ± 0.313
0.0PheXaa: 0.0 ± 0.0
Gly
2.188GlyAla: 2.188 ± 1.518
0.365GlyCys: 0.365 ± 0.198
5.47GlyAsp: 5.47 ± 0.413
4.012GlyGlu: 4.012 ± 0.825
3.647GlyPhe: 3.647 ± 2.079
2.918GlyGly: 2.918 ± 0.446
0.729GlyHis: 0.729 ± 0.396
3.647GlyIle: 3.647 ± 1.304
3.647GlyLys: 3.647 ± 1.304
2.918GlyLeu: 2.918 ± 0.446
0.0GlyMet: 0.0 ± 0.0
3.282GlyAsn: 3.282 ± 0.429
0.729GlyPro: 0.729 ± 0.281
2.918GlyGln: 2.918 ± 0.446
1.459GlyArg: 1.459 ± 1.238
2.188GlySer: 2.188 ± 0.511
4.741GlyThr: 4.741 ± 2.162
1.823GlyVal: 1.823 ± 0.313
0.0GlyTrp: 0.0 ± 0.0
2.918GlyTyr: 2.918 ± 1.122
0.0GlyXaa: 0.0 ± 0.0
His
2.188HisAla: 2.188 ± 0.165
0.0HisCys: 0.0 ± 0.0
0.729HisAsp: 0.729 ± 0.957
1.094HisGlu: 1.094 ± 0.083
2.188HisPhe: 2.188 ± 0.165
1.094HisGly: 1.094 ± 0.083
0.365HisHis: 0.365 ± 0.198
1.459HisIle: 1.459 ± 0.792
1.459HisLys: 1.459 ± 0.792
3.647HisLeu: 3.647 ± 1.304
1.094HisMet: 1.094 ± 0.083
2.553HisAsn: 2.553 ± 0.71
2.188HisPro: 2.188 ± 0.165
0.729HisGln: 0.729 ± 0.281
1.094HisArg: 1.094 ± 0.594
2.553HisSer: 2.553 ± 0.033
1.823HisThr: 1.823 ± 0.313
1.459HisVal: 1.459 ± 0.561
0.365HisTrp: 0.365 ± 0.479
2.188HisTyr: 2.188 ± 1.188
0.0HisXaa: 0.0 ± 0.0
Ile
5.106IleAla: 5.106 ± 0.611
0.729IleCys: 0.729 ± 0.396
5.47IleAsp: 5.47 ± 0.264
3.282IleGlu: 3.282 ± 1.106
2.188IlePhe: 2.188 ± 0.511
2.918IleGly: 2.918 ± 1.799
2.553IleHis: 2.553 ± 0.644
5.106IleIle: 5.106 ± 0.066
5.835IleLys: 5.835 ± 1.138
5.106IleLeu: 5.106 ± 1.419
1.823IleMet: 1.823 ± 0.313
4.012IleAsn: 4.012 ± 0.528
2.553IlePro: 2.553 ± 0.644
1.823IleGln: 1.823 ± 0.313
2.553IleArg: 2.553 ± 0.71
5.106IleSer: 5.106 ± 0.611
5.835IleThr: 5.835 ± 0.462
5.106IleVal: 5.106 ± 2.096
0.729IleTrp: 0.729 ± 0.396
3.647IleTyr: 3.647 ± 1.304
0.0IleXaa: 0.0 ± 0.0
Lys
4.741LysAla: 4.741 ± 0.544
1.094LysCys: 1.094 ± 0.594
5.47LysAsp: 5.47 ± 0.94
5.47LysGlu: 5.47 ± 2.294
2.188LysPhe: 2.188 ± 0.511
2.918LysGly: 2.918 ± 0.908
3.282LysHis: 3.282 ± 0.429
5.835LysIle: 5.835 ± 1.138
3.647LysLys: 3.647 ± 1.98
3.282LysLeu: 3.282 ± 0.248
2.188LysMet: 2.188 ± 0.294
1.823LysAsn: 1.823 ± 0.363
3.647LysPro: 3.647 ± 0.05
2.918LysGln: 2.918 ± 0.908
3.647LysArg: 3.647 ± 1.304
3.282LysSer: 3.282 ± 1.106
4.741LysThr: 4.741 ± 1.221
5.835LysVal: 5.835 ± 0.891
1.094LysTrp: 1.094 ± 0.083
2.918LysTyr: 2.918 ± 0.908
0.0LysXaa: 0.0 ± 0.0
Leu
5.835LeuAla: 5.835 ± 0.462
2.553LeuCys: 2.553 ± 1.386
5.47LeuAsp: 5.47 ± 1.766
5.835LeuGlu: 5.835 ± 0.462
3.647LeuPhe: 3.647 ± 0.627
1.823LeuGly: 1.823 ± 0.363
2.188LeuHis: 2.188 ± 0.511
4.741LeuIle: 4.741 ± 1.221
4.376LeuLys: 4.376 ± 1.023
5.47LeuLeu: 5.47 ± 0.413
1.094LeuMet: 1.094 ± 0.083
3.282LeuAsn: 3.282 ± 1.106
2.918LeuPro: 2.918 ± 1.799
2.918LeuGln: 2.918 ± 0.908
5.47LeuArg: 5.47 ± 1.089
5.835LeuSer: 5.835 ± 0.462
6.2LeuThr: 6.2 ± 2.046
3.647LeuVal: 3.647 ± 2.079
0.729LeuTrp: 0.729 ± 0.396
5.835LeuTyr: 5.835 ± 0.215
0.0LeuXaa: 0.0 ± 0.0
Met
2.553MetAla: 2.553 ± 0.033
0.0MetCys: 0.0 ± 0.0
0.365MetAsp: 0.365 ± 0.198
2.553MetGlu: 2.553 ± 0.71
0.365MetPhe: 0.365 ± 0.479
0.365MetGly: 0.365 ± 0.479
1.823MetHis: 1.823 ± 0.313
1.459MetIle: 1.459 ± 0.115
2.918MetLys: 2.918 ± 1.122
1.094MetLeu: 1.094 ± 0.594
1.459MetMet: 1.459 ± 0.792
1.459MetAsn: 1.459 ± 0.115
0.365MetPro: 0.365 ± 0.198
1.459MetGln: 1.459 ± 0.792
0.729MetArg: 0.729 ± 0.281
2.553MetSer: 2.553 ± 1.997
1.459MetThr: 1.459 ± 0.561
1.459MetVal: 1.459 ± 0.561
0.365MetTrp: 0.365 ± 0.198
1.459MetTyr: 1.459 ± 0.792
0.0MetXaa: 0.0 ± 0.0
Asn
2.918AsnAla: 2.918 ± 0.231
0.365AsnCys: 0.365 ± 0.198
2.188AsnAsp: 2.188 ± 0.842
2.188AsnGlu: 2.188 ± 0.511
2.188AsnPhe: 2.188 ± 0.511
2.553AsnGly: 2.553 ± 1.386
0.729AsnHis: 0.729 ± 0.396
4.012AsnIle: 4.012 ± 0.825
4.741AsnLys: 4.741 ± 1.898
4.376AsnLeu: 4.376 ± 1.007
1.823AsnMet: 1.823 ± 0.313
0.365AsnAsn: 0.365 ± 0.198
3.647AsnPro: 3.647 ± 0.726
3.647AsnGln: 3.647 ± 0.05
1.823AsnArg: 1.823 ± 0.313
4.741AsnSer: 4.741 ± 1.221
4.376AsnThr: 4.376 ± 0.346
3.647AsnVal: 3.647 ± 0.726
1.459AsnTrp: 1.459 ± 0.115
1.459AsnTyr: 1.459 ± 0.115
0.0AsnXaa: 0.0 ± 0.0
Pro
1.823ProAla: 1.823 ± 0.99
0.365ProCys: 0.365 ± 0.198
1.094ProAsp: 1.094 ± 0.083
2.188ProGlu: 2.188 ± 0.511
2.188ProPhe: 2.188 ± 0.842
2.188ProGly: 2.188 ± 0.842
1.823ProHis: 1.823 ± 0.363
3.647ProIle: 3.647 ± 3.432
1.823ProLys: 1.823 ± 0.313
4.376ProLeu: 4.376 ± 1.683
1.459ProMet: 1.459 ± 1.48
1.459ProAsn: 1.459 ± 1.238
2.918ProPro: 2.918 ± 0.446
1.459ProGln: 1.459 ± 0.561
0.729ProArg: 0.729 ± 0.281
3.282ProSer: 3.282 ± 0.248
3.647ProThr: 3.647 ± 0.726
2.553ProVal: 2.553 ± 0.033
0.729ProTrp: 0.729 ± 0.281
1.823ProTyr: 1.823 ± 0.363
0.0ProXaa: 0.0 ± 0.0
Gln
1.459GlnAla: 1.459 ± 1.914
0.365GlnCys: 0.365 ± 0.198
1.094GlnAsp: 1.094 ± 0.594
1.823GlnGlu: 1.823 ± 1.04
3.647GlnPhe: 3.647 ± 0.627
1.094GlnGly: 1.094 ± 0.083
1.094GlnHis: 1.094 ± 0.594
2.918GlnIle: 2.918 ± 0.231
2.918GlnLys: 2.918 ± 0.446
4.376GlnLeu: 4.376 ± 1.007
1.459GlnMet: 1.459 ± 0.115
1.094GlnAsn: 1.094 ± 0.759
1.094GlnPro: 1.094 ± 0.594
1.459GlnGln: 1.459 ± 0.115
2.188GlnArg: 2.188 ± 0.165
2.553GlnSer: 2.553 ± 0.71
2.918GlnThr: 2.918 ± 1.799
2.553GlnVal: 2.553 ± 0.644
0.0GlnTrp: 0.0 ± 0.0
2.188GlnTyr: 2.188 ± 0.511
0.0GlnXaa: 0.0 ± 0.0
Arg
1.459ArgAla: 1.459 ± 1.238
1.094ArgCys: 1.094 ± 0.083
1.459ArgAsp: 1.459 ± 0.115
2.553ArgGlu: 2.553 ± 1.32
2.188ArgPhe: 2.188 ± 1.518
1.823ArgGly: 1.823 ± 0.99
1.094ArgHis: 1.094 ± 0.594
3.647ArgIle: 3.647 ± 1.98
3.647ArgLys: 3.647 ± 1.304
3.647ArgLeu: 3.647 ± 0.627
0.365ArgMet: 0.365 ± 0.479
3.647ArgAsn: 3.647 ± 0.05
3.282ArgPro: 3.282 ± 0.248
2.188ArgGln: 2.188 ± 1.188
1.823ArgArg: 1.823 ± 0.99
4.012ArgSer: 4.012 ± 0.148
2.188ArgThr: 2.188 ± 0.842
2.918ArgVal: 2.918 ± 0.231
0.365ArgTrp: 0.365 ± 0.198
0.365ArgTyr: 0.365 ± 0.198
0.0ArgXaa: 0.0 ± 0.0
Ser
6.2SerAla: 6.2 ± 0.693
0.729SerCys: 0.729 ± 0.396
2.918SerAsp: 2.918 ± 0.908
3.282SerGlu: 3.282 ± 0.248
2.918SerPhe: 2.918 ± 0.446
5.47SerGly: 5.47 ± 1.089
2.553SerHis: 2.553 ± 0.033
4.012SerIle: 4.012 ± 0.825
4.376SerLys: 4.376 ± 1.023
3.647SerLeu: 3.647 ± 0.05
2.188SerMet: 2.188 ± 0.165
4.012SerAsn: 4.012 ± 0.148
1.823SerPro: 1.823 ± 0.363
4.012SerGln: 4.012 ± 1.205
4.012SerArg: 4.012 ± 1.881
9.482SerSer: 9.482 ± 2.294
3.282SerThr: 3.282 ± 1.601
3.282SerVal: 3.282 ± 0.248
1.459SerTrp: 1.459 ± 0.115
2.188SerTyr: 2.188 ± 0.165
0.0SerXaa: 0.0 ± 0.0
Thr
6.2ThrAla: 6.2 ± 0.017
0.729ThrCys: 0.729 ± 0.281
3.282ThrAsp: 3.282 ± 0.248
3.282ThrGlu: 3.282 ± 0.924
3.647ThrPhe: 3.647 ± 0.627
4.012ThrGly: 4.012 ± 1.205
3.647ThrHis: 3.647 ± 0.627
4.376ThrIle: 4.376 ± 0.33
4.376ThrLys: 4.376 ± 1.7
4.376ThrLeu: 4.376 ± 1.007
1.459ThrMet: 1.459 ± 0.115
2.553ThrAsn: 2.553 ± 0.71
2.553ThrPro: 2.553 ± 1.32
2.188ThrGln: 2.188 ± 0.842
3.647ThrArg: 3.647 ± 0.627
8.023ThrSer: 8.023 ± 2.409
3.647ThrThr: 3.647 ± 0.627
2.188ThrVal: 2.188 ± 2.195
0.365ThrTrp: 0.365 ± 0.198
2.918ThrTyr: 2.918 ± 0.231
0.0ThrXaa: 0.0 ± 0.0
Val
5.106ValAla: 5.106 ± 2.64
0.729ValCys: 0.729 ± 0.396
2.918ValAsp: 2.918 ± 0.231
2.918ValGlu: 2.918 ± 0.231
3.282ValPhe: 3.282 ± 0.429
2.553ValGly: 2.553 ± 0.033
0.729ValHis: 0.729 ± 0.281
3.282ValIle: 3.282 ± 0.429
4.741ValLys: 4.741 ± 0.132
4.012ValLeu: 4.012 ± 0.528
1.459ValMet: 1.459 ± 0.561
3.647ValAsn: 3.647 ± 0.627
2.918ValPro: 2.918 ± 2.475
2.553ValGln: 2.553 ± 1.997
2.188ValArg: 2.188 ± 0.165
5.835ValSer: 5.835 ± 1.568
2.188ValThr: 2.188 ± 0.511
3.647ValVal: 3.647 ± 0.726
0.0ValTrp: 0.0 ± 0.0
1.094ValTyr: 1.094 ± 0.759
0.0ValXaa: 0.0 ± 0.0
Trp
0.365TrpAla: 0.365 ± 0.198
0.0TrpCys: 0.0 ± 0.0
1.094TrpAsp: 1.094 ± 0.594
0.365TrpGlu: 0.365 ± 0.198
0.365TrpPhe: 0.365 ± 0.198
0.0TrpGly: 0.0 ± 0.0
0.729TrpHis: 0.729 ± 0.396
0.365TrpIle: 0.365 ± 0.198
0.729TrpLys: 0.729 ± 0.281
1.459TrpLeu: 1.459 ± 0.792
0.365TrpMet: 0.365 ± 0.198
0.729TrpAsn: 0.729 ± 0.957
0.0TrpPro: 0.0 ± 0.0
0.729TrpGln: 0.729 ± 0.396
0.0TrpArg: 0.0 ± 0.0
0.365TrpSer: 0.365 ± 0.198
0.0TrpThr: 0.0 ± 0.0
1.823TrpVal: 1.823 ± 0.363
0.365TrpTrp: 0.365 ± 0.198
1.094TrpTyr: 1.094 ± 0.083
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.553TyrAla: 2.553 ± 0.644
1.094TyrCys: 1.094 ± 0.083
3.282TyrAsp: 3.282 ± 1.782
1.459TyrGlu: 1.459 ± 0.115
2.188TyrPhe: 2.188 ± 0.842
4.376TyrGly: 4.376 ± 1.023
0.365TyrHis: 0.365 ± 0.198
4.741TyrIle: 4.741 ± 0.809
2.553TyrLys: 2.553 ± 1.386
4.376TyrLeu: 4.376 ± 1.683
1.459TyrMet: 1.459 ± 0.792
3.282TyrAsn: 3.282 ± 1.782
1.459TyrPro: 1.459 ± 0.561
0.729TyrGln: 0.729 ± 0.957
1.459TyrArg: 1.459 ± 0.792
2.188TyrSer: 2.188 ± 0.511
2.553TyrThr: 2.553 ± 0.033
2.188TyrVal: 2.188 ± 0.165
0.0TyrTrp: 0.0 ± 0.0
2.918TyrTyr: 2.918 ± 0.908
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2743 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski