Amino acid dipepetide frequency for Mume virus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.862AlaAla: 2.862 ± 1.53
2.504AlaCys: 2.504 ± 0.144
2.504AlaAsp: 2.504 ± 0.144
3.22AlaGlu: 3.22 ± 0.446
4.293AlaPhe: 4.293 ± 0.013
2.862AlaGly: 2.862 ± 1.53
0.716AlaHis: 0.716 ± 0.302
5.009AlaIle: 5.009 ± 1.202
4.293AlaLys: 4.293 ± 0.926
3.936AlaLeu: 3.936 ± 0.164
1.073AlaMet: 1.073 ± 0.453
2.862AlaAsn: 2.862 ± 2.442
2.504AlaPro: 2.504 ± 0.768
1.431AlaGln: 1.431 ± 0.309
3.22AlaArg: 3.22 ± 0.466
3.22AlaSer: 3.22 ± 0.466
1.073AlaThr: 1.073 ± 0.46
5.725AlaVal: 5.725 ± 0.322
1.789AlaTrp: 1.789 ± 0.755
2.147AlaTyr: 2.147 ± 0.007
0.0AlaXaa: 0.0 ± 0.0
Cys
0.716CysAla: 0.716 ± 0.302
0.716CysCys: 0.716 ± 0.611
1.073CysAsp: 1.073 ± 0.453
2.147CysGlu: 2.147 ± 0.007
1.789CysPhe: 1.789 ± 0.755
1.789CysGly: 1.789 ± 1.07
0.716CysHis: 0.716 ± 0.302
1.073CysIle: 1.073 ± 0.453
1.789CysLys: 1.789 ± 0.158
1.431CysLeu: 1.431 ± 0.309
0.358CysMet: 0.358 ± 0.151
0.716CysAsn: 0.716 ± 0.302
1.431CysPro: 1.431 ± 0.309
0.716CysGln: 0.716 ± 0.611
1.073CysArg: 1.073 ± 0.46
2.504CysSer: 2.504 ± 0.768
2.504CysThr: 2.504 ± 0.144
0.716CysVal: 0.716 ± 0.302
0.358CysTrp: 0.358 ± 0.151
0.358CysTyr: 0.358 ± 0.151
0.0CysXaa: 0.0 ± 0.0
Asp
2.147AspAla: 2.147 ± 0.007
3.578AspCys: 3.578 ± 0.315
3.22AspAsp: 3.22 ± 1.379
2.147AspGlu: 2.147 ± 0.919
3.22AspPhe: 3.22 ± 0.446
3.22AspGly: 3.22 ± 0.466
0.0AspHis: 0.0 ± 0.0
4.293AspIle: 4.293 ± 0.926
3.22AspLys: 3.22 ± 0.446
3.22AspLeu: 3.22 ± 1.359
1.789AspMet: 1.789 ± 0.755
2.862AspAsn: 2.862 ± 0.617
2.504AspPro: 2.504 ± 1.681
2.504AspGln: 2.504 ± 0.768
2.504AspArg: 2.504 ± 0.768
5.725AspSer: 5.725 ± 0.322
1.073AspThr: 1.073 ± 0.453
1.431AspVal: 1.431 ± 0.604
0.716AspTrp: 0.716 ± 0.302
1.789AspTyr: 1.789 ± 0.755
0.0AspXaa: 0.0 ± 0.0
Glu
3.936GluAla: 3.936 ± 1.077
1.073GluCys: 1.073 ± 0.453
2.862GluAsp: 2.862 ± 0.617
3.22GluGlu: 3.22 ± 0.446
3.578GluPhe: 3.578 ± 0.315
2.862GluGly: 2.862 ± 0.295
1.431GluHis: 1.431 ± 0.604
3.22GluIle: 3.22 ± 0.446
2.862GluLys: 2.862 ± 1.208
6.082GluLeu: 6.082 ± 2.567
2.147GluMet: 2.147 ± 0.906
3.22GluAsn: 3.22 ± 1.379
3.936GluPro: 3.936 ± 1.077
1.431GluGln: 1.431 ± 0.604
2.147GluArg: 2.147 ± 0.007
6.082GluSer: 6.082 ± 0.742
2.504GluThr: 2.504 ± 1.057
3.936GluVal: 3.936 ± 1.077
0.358GluTrp: 0.358 ± 0.151
1.431GluTyr: 1.431 ± 0.309
0.0GluXaa: 0.0 ± 0.0
Phe
3.578PheAla: 3.578 ± 1.51
1.789PheCys: 1.789 ± 0.755
4.651PheAsp: 4.651 ± 0.138
4.651PheGlu: 4.651 ± 1.051
5.725PhePhe: 5.725 ± 1.504
3.936PheGly: 3.936 ± 0.164
0.358PheHis: 0.358 ± 0.151
3.22PheIle: 3.22 ± 0.466
5.009PheLys: 5.009 ± 1.536
6.082PheLeu: 6.082 ± 1.083
0.716PheMet: 0.716 ± 0.302
3.578PheAsn: 3.578 ± 0.315
2.147PhePro: 2.147 ± 0.906
1.789PheGln: 1.789 ± 1.983
3.22PheArg: 3.22 ± 0.446
6.082PheSer: 6.082 ± 0.171
1.789PheThr: 1.789 ± 0.755
1.073PheVal: 1.073 ± 0.453
1.073PheTrp: 1.073 ± 0.46
1.431PheTyr: 1.431 ± 0.604
0.0PheXaa: 0.0 ± 0.0
Gly
3.936GlyAla: 3.936 ± 1.989
0.716GlyCys: 0.716 ± 1.523
4.651GlyAsp: 4.651 ± 0.775
3.578GlyGlu: 3.578 ± 0.315
2.504GlyPhe: 2.504 ± 0.144
2.147GlyGly: 2.147 ± 1.832
1.073GlyHis: 1.073 ± 0.453
2.862GlyIle: 2.862 ± 0.295
3.22GlyLys: 3.22 ± 0.446
3.936GlyLeu: 3.936 ± 0.749
0.716GlyMet: 0.716 ± 0.611
1.789GlyAsn: 1.789 ± 0.158
1.073GlyPro: 1.073 ± 0.46
2.862GlyGln: 2.862 ± 1.208
1.431GlyArg: 1.431 ± 0.309
7.871GlySer: 7.871 ± 3.066
0.716GlyThr: 0.716 ± 0.302
3.936GlyVal: 3.936 ± 1.077
0.716GlyTrp: 0.716 ± 0.302
0.358GlyTyr: 0.358 ± 0.151
0.0GlyXaa: 0.0 ± 0.0
His
1.789HisAla: 1.789 ± 1.07
0.0HisCys: 0.0 ± 0.0
1.073HisAsp: 1.073 ± 0.453
1.073HisGlu: 1.073 ± 1.372
1.073HisPhe: 1.073 ± 0.453
0.716HisGly: 0.716 ± 0.302
2.147HisHis: 2.147 ± 0.906
2.147HisIle: 2.147 ± 1.832
0.358HisLys: 0.358 ± 0.151
4.651HisLeu: 4.651 ± 1.051
0.716HisMet: 0.716 ± 1.006
1.431HisAsn: 1.431 ± 0.309
1.073HisPro: 1.073 ± 0.453
1.789HisGln: 1.789 ± 0.755
0.358HisArg: 0.358 ± 0.151
2.504HisSer: 2.504 ± 1.057
1.073HisThr: 1.073 ± 0.453
0.358HisVal: 0.358 ± 0.151
0.0HisTrp: 0.0 ± 0.0
1.431HisTyr: 1.431 ± 0.309
0.0HisXaa: 0.0 ± 0.0
Ile
3.936IleAla: 3.936 ± 0.164
1.073IleCys: 1.073 ± 0.46
4.293IleAsp: 4.293 ± 0.926
4.651IleGlu: 4.651 ± 1.051
3.936IlePhe: 3.936 ± 0.164
3.936IleGly: 3.936 ± 0.164
3.22IleHis: 3.22 ± 0.466
2.862IleIle: 2.862 ± 0.295
6.798IleLys: 6.798 ± 1.957
6.44IleLeu: 6.44 ± 2.718
2.147IleMet: 2.147 ± 0.906
3.22IleAsn: 3.22 ± 0.446
3.22IlePro: 3.22 ± 0.466
3.578IleGln: 3.578 ± 1.51
2.147IleArg: 2.147 ± 0.919
7.156IleSer: 7.156 ± 0.282
2.862IleThr: 2.862 ± 0.295
4.651IleVal: 4.651 ± 1.051
1.073IleTrp: 1.073 ± 0.46
1.431IleTyr: 1.431 ± 0.309
0.0IleXaa: 0.0 ± 0.0
Lys
4.293LysAla: 4.293 ± 1.812
1.431LysCys: 1.431 ± 0.604
3.936LysAsp: 3.936 ± 0.749
2.862LysGlu: 2.862 ± 0.295
2.504LysPhe: 2.504 ± 0.768
4.651LysGly: 4.651 ± 0.775
1.789LysHis: 1.789 ± 0.158
4.651LysIle: 4.651 ± 1.051
5.009LysLys: 5.009 ± 1.202
6.798LysLeu: 6.798 ± 1.957
2.147LysMet: 2.147 ± 0.007
3.578LysAsn: 3.578 ± 0.597
1.789LysPro: 1.789 ± 0.158
2.862LysGln: 2.862 ± 0.295
3.578LysArg: 3.578 ± 1.228
7.513LysSer: 7.513 ± 1.346
3.936LysThr: 3.936 ± 0.164
6.082LysVal: 6.082 ± 1.655
0.0LysTrp: 0.0 ± 0.0
1.789LysTyr: 1.789 ± 0.158
0.0LysXaa: 0.0 ± 0.0
Leu
7.513LeuAla: 7.513 ± 2.259
3.936LeuCys: 3.936 ± 1.661
4.651LeuAsp: 4.651 ± 0.775
3.578LeuGlu: 3.578 ± 0.597
6.44LeuPhe: 6.44 ± 0.02
4.651LeuGly: 4.651 ± 1.963
2.147LeuHis: 2.147 ± 0.919
8.229LeuIle: 8.229 ± 0.735
10.376LeuLys: 10.376 ± 3.467
8.945LeuLeu: 8.945 ± 2.863
1.789LeuMet: 1.789 ± 0.158
5.009LeuAsn: 5.009 ± 2.114
4.651LeuPro: 4.651 ± 0.775
3.22LeuGln: 3.22 ± 0.446
3.936LeuArg: 3.936 ± 1.661
10.376LeuSer: 10.376 ± 2.554
4.293LeuThr: 4.293 ± 1.812
3.22LeuVal: 3.22 ± 0.446
0.358LeuTrp: 0.358 ± 0.151
0.716LeuTyr: 0.716 ± 0.611
0.0LeuXaa: 0.0 ± 0.0
Met
0.716MetAla: 0.716 ± 0.611
0.358MetCys: 0.358 ± 0.151
0.358MetAsp: 0.358 ± 0.151
1.073MetGlu: 1.073 ± 0.46
0.716MetPhe: 0.716 ± 0.302
1.073MetGly: 1.073 ± 1.372
0.716MetHis: 0.716 ± 0.302
1.073MetIle: 1.073 ± 0.453
1.431MetLys: 1.431 ± 0.604
2.504MetLeu: 2.504 ± 1.057
1.073MetMet: 1.073 ± 0.453
0.716MetAsn: 0.716 ± 0.302
1.073MetPro: 1.073 ± 0.453
1.073MetGln: 1.073 ± 0.46
2.862MetArg: 2.862 ± 0.295
1.789MetSer: 1.789 ± 1.07
1.073MetThr: 1.073 ± 0.453
0.716MetVal: 0.716 ± 0.302
0.0MetTrp: 0.0 ± 0.0
1.073MetTyr: 1.073 ± 0.46
0.0MetXaa: 0.0 ± 0.0
Asn
2.862AsnAla: 2.862 ± 0.295
1.073AsnCys: 1.073 ± 0.46
2.147AsnAsp: 2.147 ± 0.906
1.789AsnGlu: 1.789 ± 0.158
4.651AsnPhe: 4.651 ± 0.138
1.073AsnGly: 1.073 ± 0.453
1.789AsnHis: 1.789 ± 0.158
1.073AsnIle: 1.073 ± 0.453
4.293AsnLys: 4.293 ± 2.751
6.798AsnLeu: 6.798 ± 0.131
0.358AsnMet: 0.358 ± 0.151
2.504AsnAsn: 2.504 ± 0.768
3.578AsnPro: 3.578 ± 0.597
2.504AsnGln: 2.504 ± 0.144
2.504AsnArg: 2.504 ± 1.681
4.293AsnSer: 4.293 ± 0.926
1.789AsnThr: 1.789 ± 1.07
0.716AsnVal: 0.716 ± 0.302
0.0AsnTrp: 0.0 ± 0.0
2.147AsnTyr: 2.147 ± 0.007
0.0AsnXaa: 0.0 ± 0.0
Pro
2.862ProAla: 2.862 ± 1.53
0.0ProCys: 0.0 ± 0.0
2.504ProAsp: 2.504 ± 0.768
4.293ProGlu: 4.293 ± 0.013
2.504ProPhe: 2.504 ± 0.144
1.073ProGly: 1.073 ± 0.453
1.073ProHis: 1.073 ± 0.453
5.009ProIle: 5.009 ± 0.289
1.073ProLys: 1.073 ± 0.453
3.578ProLeu: 3.578 ± 0.597
0.358ProMet: 0.358 ± 0.762
3.22ProAsn: 3.22 ± 2.291
1.431ProPro: 1.431 ± 1.221
1.789ProGln: 1.789 ± 0.158
2.504ProArg: 2.504 ± 1.681
2.147ProSer: 2.147 ± 0.007
3.22ProThr: 3.22 ± 1.379
2.147ProVal: 2.147 ± 0.007
0.358ProTrp: 0.358 ± 0.151
0.716ProTyr: 0.716 ± 0.302
0.0ProXaa: 0.0 ± 0.0
Gln
3.578GlnAla: 3.578 ± 1.228
1.073GlnCys: 1.073 ± 0.453
2.147GlnAsp: 2.147 ± 0.906
1.789GlnGlu: 1.789 ± 0.158
1.789GlnPhe: 1.789 ± 1.983
2.504GlnGly: 2.504 ± 0.768
0.716GlnHis: 0.716 ± 0.302
3.578GlnIle: 3.578 ± 1.51
1.789GlnLys: 1.789 ± 0.158
2.862GlnLeu: 2.862 ± 0.295
0.358GlnMet: 0.358 ± 0.151
1.789GlnAsn: 1.789 ± 0.755
1.789GlnPro: 1.789 ± 1.07
2.862GlnGln: 2.862 ± 0.295
1.789GlnArg: 1.789 ± 0.755
4.293GlnSer: 4.293 ± 1.838
1.789GlnThr: 1.789 ± 1.07
2.862GlnVal: 2.862 ± 0.295
0.716GlnTrp: 0.716 ± 0.302
1.073GlnTyr: 1.073 ± 0.453
0.0GlnXaa: 0.0 ± 0.0
Arg
3.936ArgAla: 3.936 ± 1.077
0.716ArgCys: 0.716 ± 0.302
1.073ArgAsp: 1.073 ± 0.46
2.862ArgGlu: 2.862 ± 0.295
3.578ArgPhe: 3.578 ± 0.315
1.789ArgGly: 1.789 ± 1.983
1.073ArgHis: 1.073 ± 0.46
4.293ArgIle: 4.293 ± 0.926
4.293ArgLys: 4.293 ± 0.013
4.651ArgLeu: 4.651 ± 0.138
0.716ArgMet: 0.716 ± 0.302
1.073ArgAsn: 1.073 ± 0.453
2.504ArgPro: 2.504 ± 0.144
2.504ArgGln: 2.504 ± 0.768
3.22ArgArg: 3.22 ± 0.466
3.578ArgSer: 3.578 ± 1.228
1.789ArgThr: 1.789 ± 1.983
2.147ArgVal: 2.147 ± 0.906
0.358ArgTrp: 0.358 ± 0.151
2.504ArgTyr: 2.504 ± 0.768
0.0ArgXaa: 0.0 ± 0.0
Ser
3.578SerAla: 3.578 ± 0.315
2.147SerCys: 2.147 ± 0.919
3.22SerAsp: 3.22 ± 1.379
6.44SerGlu: 6.44 ± 1.806
7.871SerPhe: 7.871 ± 0.584
4.651SerGly: 4.651 ± 2.6
3.22SerHis: 3.22 ± 0.446
7.156SerIle: 7.156 ± 0.63
6.44SerLys: 6.44 ± 1.806
10.376SerLeu: 10.376 ± 2.554
1.789SerMet: 1.789 ± 0.697
6.798SerAsn: 6.798 ± 1.694
1.431SerPro: 1.431 ± 0.604
3.22SerGln: 3.22 ± 0.446
6.082SerArg: 6.082 ± 1.083
10.018SerSer: 10.018 ± 5.81
4.651SerThr: 4.651 ± 1.687
5.367SerVal: 5.367 ± 0.473
1.073SerTrp: 1.073 ± 0.453
3.22SerTyr: 3.22 ± 0.466
0.0SerXaa: 0.0 ± 0.0
Thr
1.431ThrAla: 1.431 ± 1.221
0.358ThrCys: 0.358 ± 0.762
2.147ThrAsp: 2.147 ± 0.919
4.651ThrGlu: 4.651 ± 1.051
2.504ThrPhe: 2.504 ± 1.057
2.504ThrGly: 2.504 ± 0.768
1.073ThrHis: 1.073 ± 0.453
2.862ThrIle: 2.862 ± 0.295
2.862ThrLys: 2.862 ± 1.208
5.367ThrLeu: 5.367 ± 1.353
1.073ThrMet: 1.073 ± 1.372
1.073ThrAsn: 1.073 ± 0.46
1.431ThrPro: 1.431 ± 0.309
1.073ThrGln: 1.073 ± 1.372
2.147ThrArg: 2.147 ± 0.007
5.367ThrSer: 5.367 ± 1.353
2.504ThrThr: 2.504 ± 0.144
2.147ThrVal: 2.147 ± 0.007
0.358ThrTrp: 0.358 ± 0.762
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.504ValAla: 2.504 ± 0.144
0.716ValCys: 0.716 ± 0.302
2.147ValAsp: 2.147 ± 0.906
2.147ValGlu: 2.147 ± 0.919
2.147ValPhe: 2.147 ± 0.007
3.22ValGly: 3.22 ± 1.359
2.504ValHis: 2.504 ± 1.681
5.725ValIle: 5.725 ± 2.416
5.367ValLys: 5.367 ± 0.44
4.293ValLeu: 4.293 ± 0.013
1.789ValMet: 1.789 ± 0.158
1.431ValAsn: 1.431 ± 0.604
1.789ValPro: 1.789 ± 1.07
2.862ValGln: 2.862 ± 0.295
1.789ValArg: 1.789 ± 0.158
3.578ValSer: 3.578 ± 0.597
2.862ValThr: 2.862 ± 0.295
2.504ValVal: 2.504 ± 1.057
0.358ValTrp: 0.358 ± 0.151
1.431ValTyr: 1.431 ± 0.604
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.073TrpAsp: 1.073 ± 0.453
0.358TrpGlu: 0.358 ± 0.151
0.0TrpPhe: 0.0 ± 0.0
0.358TrpGly: 0.358 ± 0.151
0.0TrpHis: 0.0 ± 0.0
1.073TrpIle: 1.073 ± 0.453
0.0TrpLys: 0.0 ± 0.0
1.073TrpLeu: 1.073 ± 0.453
0.0TrpMet: 0.0 ± 0.0
0.358TrpAsn: 0.358 ± 0.151
1.073TrpPro: 1.073 ± 0.46
0.358TrpGln: 0.358 ± 0.762
1.073TrpArg: 1.073 ± 0.46
1.431TrpSer: 1.431 ± 0.604
0.716TrpThr: 0.716 ± 0.302
1.073TrpVal: 1.073 ± 0.453
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.073TyrAla: 1.073 ± 0.46
0.716TyrCys: 0.716 ± 0.611
1.431TyrAsp: 1.431 ± 0.309
1.789TyrGlu: 1.789 ± 0.755
1.073TyrPhe: 1.073 ± 0.453
1.073TyrGly: 1.073 ± 0.453
0.358TyrHis: 0.358 ± 0.762
3.22TyrIle: 3.22 ± 0.446
0.716TyrLys: 0.716 ± 0.302
5.009TyrLeu: 5.009 ± 1.202
0.0TyrMet: 0.0 ± 0.0
0.716TyrAsn: 0.716 ± 0.302
1.431TyrPro: 1.431 ± 0.309
0.716TyrGln: 0.716 ± 0.611
1.073TyrArg: 1.073 ± 1.372
3.22TyrSer: 3.22 ± 0.466
0.716TyrThr: 0.716 ± 0.302
0.358TyrVal: 0.358 ± 0.151
0.358TyrTrp: 0.358 ± 0.151
0.716TyrTyr: 0.716 ± 0.302
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2796 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski