Amino acid dipepetide frequency for Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.079AlaAla: 7.079 ± 0.045	1.597AlaCys: 1.597 ± 0.014	3.078AlaAsp: 3.078 ± 0.019	4.869AlaGlu: 4.869 ± 0.029	2.769AlaPhe: 2.769 ± 0.018	5.187AlaGly: 5.187 ± 0.029	1.694AlaHis: 1.694 ± 0.016	2.791AlaIle: 2.791 ± 0.02	3.332AlaLys: 3.332 ± 0.026	7.96AlaLeu: 7.96 ± 0.042	1.57AlaMet: 1.57 ± 0.014	1.967AlaAsn: 1.967 ± 0.017	4.472AlaPro: 4.472 ± 0.035	3.458AlaGln: 3.458 ± 0.026	3.992AlaArg: 3.992 ± 0.027	5.97AlaSer: 5.97 ± 0.033	3.634AlaThr: 3.634 ± 0.028	5.347AlaVal: 5.347 ± 0.028	0.916AlaTrp: 0.916 ± 0.011	1.545AlaTyr: 1.545 ± 0.015	0.015AlaXaa: 0.015 ± 0.001
Cys	1.521CysAla: 1.521 ± 0.018	0.752CysCys: 0.752 ± 0.014	1.098CysAsp: 1.098 ± 0.016	1.246CysGlu: 1.246 ± 0.018	0.915CysPhe: 0.915 ± 0.011	1.781CysGly: 1.781 ± 0.02	0.704CysHis: 0.704 ± 0.01	0.938CysIle: 0.938 ± 0.013	1.03CysLys: 1.03 ± 0.013	2.334CysLeu: 2.334 ± 0.019	0.443CysMet: 0.443 ± 0.007	0.709CysAsn: 0.709 ± 0.011	1.634CysPro: 1.634 ± 0.025	1.115CysGln: 1.115 ± 0.015	1.445CysArg: 1.445 ± 0.017	2.171CysSer: 2.171 ± 0.024	1.17CysThr: 1.17 ± 0.013	1.499CysVal: 1.499 ± 0.018	0.348CysTrp: 0.348 ± 0.007	0.6CysTyr: 0.6 ± 0.009	0.001CysXaa: 0.001 ± 0.0
Asp	3.001AspAla: 3.001 ± 0.017	1.065AspCys: 1.065 ± 0.015	2.486AspAsp: 2.486 ± 0.024	3.306AspGlu: 3.306 ± 0.023	2.08AspPhe: 2.08 ± 0.016	3.321AspGly: 3.321 ± 0.028	1.129AspHis: 1.129 ± 0.011	2.391AspIle: 2.391 ± 0.021	2.303AspLys: 2.303 ± 0.018	5.019AspLeu: 5.019 ± 0.026	1.111AspMet: 1.111 ± 0.012	1.548AspAsn: 1.548 ± 0.015	2.999AspPro: 2.999 ± 0.022	1.826AspGln: 1.826 ± 0.016	2.52AspArg: 2.52 ± 0.021	4.068AspSer: 4.068 ± 0.027	2.514AspThr: 2.514 ± 0.019	3.209AspVal: 3.209 ± 0.025	0.66AspTrp: 0.66 ± 0.009	1.364AspTyr: 1.364 ± 0.017	0.002AspXaa: 0.002 ± 0.0
Glu	5.447GluAla: 5.447 ± 0.032	1.177GluCys: 1.177 ± 0.022	4.293GluAsp: 4.293 ± 0.025	7.417GluGlu: 7.417 ± 0.053	1.953GluPhe: 1.953 ± 0.016	4.501GluGly: 4.501 ± 0.027	1.457GluHis: 1.457 ± 0.015	2.799GluIle: 2.799 ± 0.021	4.712GluLys: 4.712 ± 0.038	6.388GluLeu: 6.388 ± 0.04	1.625GluMet: 1.625 ± 0.015	2.72GluAsn: 2.72 ± 0.022	3.252GluPro: 3.252 ± 0.027	3.164GluGln: 3.164 ± 0.028	3.897GluArg: 3.897 ± 0.031	4.135GluSer: 4.135 ± 0.024	3.204GluThr: 3.204 ± 0.022	4.24GluVal: 4.24 ± 0.028	0.705GluTrp: 0.705 ± 0.01	1.431GluTyr: 1.431 ± 0.014	0.003GluXaa: 0.003 ± 0.001
Phe	2.071PheAla: 2.071 ± 0.017	1.071PheCys: 1.071 ± 0.012	1.615PheAsp: 1.615 ± 0.013	1.881PheGlu: 1.881 ± 0.017	1.636PhePhe: 1.636 ± 0.015	2.288PheGly: 2.288 ± 0.017	1.018PheHis: 1.018 ± 0.011	1.766PheIle: 1.766 ± 0.016	1.573PheLys: 1.573 ± 0.017	4.363PheLeu: 4.363 ± 0.025	0.774PheMet: 0.774 ± 0.01	1.199PheAsn: 1.199 ± 0.012	2.094PhePro: 2.094 ± 0.016	1.789PheGln: 1.789 ± 0.015	2.023PheArg: 2.023 ± 0.02	3.419PheSer: 3.419 ± 0.021	2.048PheThr: 2.048 ± 0.017	2.237PheVal: 2.237 ± 0.02	0.529PheTrp: 0.529 ± 0.008	1.172PheTyr: 1.172 ± 0.012	0.001PheXaa: 0.001 ± 0.0
Gly	5.006GlyAla: 5.006 ± 0.032	1.503GlyCys: 1.503 ± 0.017	3.242GlyAsp: 3.242 ± 0.024	4.058GlyGlu: 4.058 ± 0.023	2.541GlyPhe: 2.541 ± 0.019	5.25GlyGly: 5.25 ± 0.042	1.812GlyHis: 1.812 ± 0.018	2.67GlyIle: 2.67 ± 0.023	3.57GlyLys: 3.57 ± 0.024	6.53GlyLeu: 6.53 ± 0.035	1.308GlyMet: 1.308 ± 0.015	2.294GlyAsn: 2.294 ± 0.02	4.633GlyPro: 4.633 ± 0.033	3.004GlyGln: 3.004 ± 0.022	4.12GlyArg: 4.12 ± 0.024	6.009GlySer: 6.009 ± 0.035	3.832GlyThr: 3.832 ± 0.025	3.924GlyVal: 3.924 ± 0.027	0.876GlyTrp: 0.876 ± 0.012	1.696GlyTyr: 1.696 ± 0.02	0.014GlyXaa: 0.014 ± 0.001
His	1.389HisAla: 1.389 ± 0.014	0.737HisCys: 0.737 ± 0.012	0.846HisAsp: 0.846 ± 0.012	1.231HisGlu: 1.231 ± 0.011	1.115HisPhe: 1.115 ± 0.011	1.635HisGly: 1.635 ± 0.015	0.822HisHis: 0.822 ± 0.011	1.156HisIle: 1.156 ± 0.013	1.115HisLys: 1.115 ± 0.012	2.994HisLeu: 2.994 ± 0.022	0.572HisMet: 0.572 ± 0.009	0.779HisAsn: 0.779 ± 0.011	1.704HisPro: 1.704 ± 0.02	1.225HisGln: 1.225 ± 0.012	1.659HisArg: 1.659 ± 0.016	2.188HisSer: 2.188 ± 0.017	1.392HisThr: 1.392 ± 0.013	1.613HisVal: 1.613 ± 0.014	0.383HisTrp: 0.383 ± 0.007	0.793HisTyr: 0.793 ± 0.009	0.002HisXaa: 0.002 ± 0.0
Ile	2.468IleAla: 2.468 ± 0.019	1.088IleCys: 1.088 ± 0.013	1.852IleAsp: 1.852 ± 0.016	2.204IleGlu: 2.204 ± 0.019	1.809IlePhe: 1.809 ± 0.019	2.088IleGly: 2.088 ± 0.019	1.166IleHis: 1.166 ± 0.014	2.13IleIle: 2.13 ± 0.018	2.19IleLys: 2.19 ± 0.018	4.45IleLeu: 4.45 ± 0.028	0.96IleMet: 0.96 ± 0.012	1.58IleAsn: 1.58 ± 0.016	2.424IlePro: 2.424 ± 0.021	2.098IleGln: 2.098 ± 0.017	2.331IleArg: 2.331 ± 0.018	3.483IleSer: 3.483 ± 0.026	2.408IleThr: 2.408 ± 0.019	2.435IleVal: 2.435 ± 0.021	0.504IleTrp: 0.504 ± 0.007	1.329IleTyr: 1.329 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.015LysAla: 4.015 ± 0.026	0.968LysCys: 0.968 ± 0.014	2.822LysAsp: 2.822 ± 0.02	4.528LysGlu: 4.528 ± 0.034	1.572LysPhe: 1.572 ± 0.016	3.161LysGly: 3.161 ± 0.025	1.226LysHis: 1.226 ± 0.015	2.314LysIle: 2.314 ± 0.019	3.926LysLys: 3.926 ± 0.042	4.783LysLeu: 4.783 ± 0.033	1.351LysMet: 1.351 ± 0.014	1.983LysAsn: 1.983 ± 0.019	2.795LysPro: 2.795 ± 0.025	2.352LysGln: 2.352 ± 0.021	3.075LysArg: 3.075 ± 0.025	3.436LysSer: 3.436 ± 0.026	2.79LysThr: 2.79 ± 0.02	3.325LysVal: 3.325 ± 0.024	0.557LysTrp: 0.557 ± 0.009	1.382LysTyr: 1.382 ± 0.014	0.003LysXaa: 0.003 ± 0.001
Leu	7.476LeuAla: 7.476 ± 0.037	2.494LeuCys: 2.494 ± 0.02	4.812LeuAsp: 4.812 ± 0.024	7.076LeuGlu: 7.076 ± 0.046	3.521LeuPhe: 3.521 ± 0.025	6.611LeuGly: 6.611 ± 0.032	2.781LeuHis: 2.781 ± 0.019	3.775LeuIle: 3.775 ± 0.024	5.298LeuLys: 5.298 ± 0.035	11.508LeuLeu: 11.508 ± 0.057	2.108LeuMet: 2.108 ± 0.02	3.23LeuAsn: 3.23 ± 0.022	6.248LeuPro: 6.248 ± 0.031	5.743LeuGln: 5.743 ± 0.042	6.487LeuArg: 6.487 ± 0.036	8.327LeuSer: 8.327 ± 0.036	5.3LeuThr: 5.3 ± 0.032	6.236LeuVal: 6.236 ± 0.033	1.308LeuTrp: 1.308 ± 0.013	2.457LeuTyr: 2.457 ± 0.02	0.008LeuXaa: 0.008 ± 0.001
Met	1.968MetAla: 1.968 ± 0.017	0.435MetCys: 0.435 ± 0.009	1.208MetAsp: 1.208 ± 0.013	1.737MetGlu: 1.737 ± 0.016	0.733MetPhe: 0.733 ± 0.01	1.37MetGly: 1.37 ± 0.015	0.446MetHis: 0.446 ± 0.006	0.788MetIle: 0.788 ± 0.01	1.326MetLys: 1.326 ± 0.015	2.09MetLeu: 2.09 ± 0.019	0.547MetMet: 0.547 ± 0.009	0.813MetAsn: 0.813 ± 0.011	1.105MetPro: 1.105 ± 0.013	0.911MetGln: 0.911 ± 0.011	1.116MetArg: 1.116 ± 0.011	1.534MetSer: 1.534 ± 0.013	1.125MetThr: 1.125 ± 0.013	1.476MetVal: 1.476 ± 0.014	0.26MetTrp: 0.26 ± 0.005	0.61MetTyr: 0.61 ± 0.008	0.001MetXaa: 0.001 ± 0.0
Asn	1.996AsnAla: 1.996 ± 0.018	0.771AsnCys: 0.771 ± 0.01	1.359AsnAsp: 1.359 ± 0.015	1.911AsnGlu: 1.911 ± 0.019	1.332AsnPhe: 1.332 ± 0.014	2.235AsnGly: 2.235 ± 0.021	0.844AsnHis: 0.844 ± 0.01	1.786AsnIle: 1.786 ± 0.016	1.875AsnLys: 1.875 ± 0.018	3.402AsnLeu: 3.402 ± 0.022	0.804AsnMet: 0.804 ± 0.009	1.243AsnAsn: 1.243 ± 0.014	2.094AsnPro: 2.094 ± 0.017	1.496AsnGln: 1.496 ± 0.017	1.721AsnArg: 1.721 ± 0.015	2.747AsnSer: 2.747 ± 0.019	1.756AsnThr: 1.756 ± 0.017	2.077AsnVal: 2.077 ± 0.017	0.421AsnTrp: 0.421 ± 0.007	0.98AsnTyr: 0.98 ± 0.012	0.001AsnXaa: 0.001 ± 0.0
Pro	5.036ProAla: 5.036 ± 0.037	1.375ProCys: 1.375 ± 0.019	2.861ProAsp: 2.861 ± 0.023	4.559ProGlu: 4.559 ± 0.029	1.983ProPhe: 1.983 ± 0.018	5.489ProGly: 5.489 ± 0.041	1.47ProHis: 1.47 ± 0.013	1.72ProIle: 1.72 ± 0.014	2.649ProLys: 2.649 ± 0.025	5.642ProLeu: 5.642 ± 0.032	1.113ProMet: 1.113 ± 0.015	1.645ProAsn: 1.645 ± 0.016	5.538ProPro: 5.538 ± 0.055	2.856ProGln: 2.856 ± 0.022	3.612ProArg: 3.612 ± 0.029	5.603ProSer: 5.603 ± 0.038	3.031ProThr: 3.031 ± 0.024	3.935ProVal: 3.935 ± 0.025	0.824ProTrp: 0.824 ± 0.01	1.331ProTyr: 1.331 ± 0.014	0.017ProXaa: 0.017 ± 0.001
Gln	3.674GlnAla: 3.674 ± 0.03	0.943GlnCys: 0.943 ± 0.013	2.362GlnAsp: 2.362 ± 0.019	3.823GlnGlu: 3.823 ± 0.028	1.292GlnPhe: 1.292 ± 0.011	3.146GlnGly: 3.146 ± 0.022	1.272GlnHis: 1.272 ± 0.016	1.841GlnIle: 1.841 ± 0.018	2.664GlnLys: 2.664 ± 0.022	4.834GlnLeu: 4.834 ± 0.035	1.102GlnMet: 1.102 ± 0.011	1.655GlnAsn: 1.655 ± 0.016	2.773GlnPro: 2.773 ± 0.023	2.821GlnGln: 2.821 ± 0.032	2.987GlnArg: 2.987 ± 0.024	3.02GlnSer: 3.02 ± 0.021	2.263GlnThr: 2.263 ± 0.018	2.984GlnVal: 2.984 ± 0.023	0.563GlnTrp: 0.563 ± 0.008	1.063GlnTyr: 1.063 ± 0.011	0.004GlnXaa: 0.004 ± 0.001
Arg	4.419ArgAla: 4.419 ± 0.027	1.385ArgCys: 1.385 ± 0.018	2.776ArgAsp: 2.776 ± 0.022	4.056ArgGlu: 4.056 ± 0.03	1.918ArgPhe: 1.918 ± 0.017	4.029ArgGly: 4.029 ± 0.028	1.556ArgHis: 1.556 ± 0.016	2.254ArgIle: 2.254 ± 0.019	3.524ArgLys: 3.524 ± 0.024	5.713ArgLeu: 5.713 ± 0.032	1.212ArgMet: 1.212 ± 0.014	1.994ArgAsn: 1.994 ± 0.018	3.366ArgPro: 3.366 ± 0.026	2.706ArgGln: 2.706 ± 0.02	4.385ArgArg: 4.385 ± 0.036	4.248ArgSer: 4.248 ± 0.026	2.879ArgThr: 2.879 ± 0.02	3.586ArgVal: 3.586 ± 0.023	0.76ArgTrp: 0.76 ± 0.01	1.519ArgTyr: 1.519 ± 0.015	0.011ArgXaa: 0.011 ± 0.001
Ser	5.538SerAla: 5.538 ± 0.032	2.051SerCys: 2.051 ± 0.021	3.833SerAsp: 3.833 ± 0.026	4.989SerGlu: 4.989 ± 0.035	3.045SerPhe: 3.045 ± 0.02	5.805SerGly: 5.805 ± 0.033	2.076SerHis: 2.076 ± 0.019	3.035SerIle: 3.035 ± 0.021	3.603SerLys: 3.603 ± 0.025	8.31SerLeu: 8.31 ± 0.039	1.544SerMet: 1.544 ± 0.016	2.309SerAsn: 2.309 ± 0.019	5.851SerPro: 5.851 ± 0.043	3.687SerGln: 3.687 ± 0.023	4.663SerArg: 4.663 ± 0.03	8.806SerSer: 8.806 ± 0.072	4.256SerThr: 4.256 ± 0.029	5.144SerVal: 5.144 ± 0.031	1.141SerTrp: 1.141 ± 0.011	2.037SerTyr: 2.037 ± 0.018	0.007SerXaa: 0.007 ± 0.001
Thr	3.998ThrAla: 3.998 ± 0.024	1.461ThrCys: 1.461 ± 0.021	2.414ThrAsp: 2.414 ± 0.019	3.405ThrGlu: 3.405 ± 0.021	2.08ThrPhe: 2.08 ± 0.017	3.62ThrGly: 3.62 ± 0.026	1.236ThrHis: 1.236 ± 0.013	2.233ThrIle: 2.233 ± 0.019	2.415ThrLys: 2.415 ± 0.019	5.47ThrLeu: 5.47 ± 0.028	1.107ThrMet: 1.107 ± 0.012	1.544ThrAsn: 1.544 ± 0.015	3.441ThrPro: 3.441 ± 0.028	2.263ThrGln: 2.263 ± 0.02	2.581ThrArg: 2.581 ± 0.02	4.404ThrSer: 4.404 ± 0.028	2.79ThrThr: 2.79 ± 0.027	4.087ThrVal: 4.087 ± 0.028	0.723ThrTrp: 0.723 ± 0.01	1.405ThrTyr: 1.405 ± 0.015	0.004ThrXaa: 0.004 ± 0.001
Val	4.718ValAla: 4.718 ± 0.025	1.629ValCys: 1.629 ± 0.017	3.051ValAsp: 3.051 ± 0.024	3.857ValGlu: 3.857 ± 0.023	2.588ValPhe: 2.588 ± 0.019	3.834ValGly: 3.834 ± 0.028	1.588ValHis: 1.588 ± 0.016	2.89ValIle: 2.89 ± 0.021	3.244ValLys: 3.244 ± 0.024	7.035ValLeu: 7.035 ± 0.034	1.451ValMet: 1.451 ± 0.015	2.159ValAsn: 2.159 ± 0.02	3.981ValPro: 3.981 ± 0.025	2.829ValGln: 2.829 ± 0.021	3.32ValArg: 3.32 ± 0.024	5.15ValSer: 5.15 ± 0.03	4.073ValThr: 4.073 ± 0.028	4.434ValVal: 4.434 ± 0.028	0.812ValTrp: 0.812 ± 0.01	1.641ValTyr: 1.641 ± 0.017	0.003ValXaa: 0.003 ± 0.001
Trp	0.979TrpAla: 0.979 ± 0.013	0.279TrpCys: 0.279 ± 0.006	0.661TrpAsp: 0.661 ± 0.009	0.839TrpGlu: 0.839 ± 0.012	0.47TrpPhe: 0.47 ± 0.008	0.892TrpGly: 0.892 ± 0.012	0.332TrpHis: 0.332 ± 0.006	0.494TrpIle: 0.494 ± 0.008	0.769TrpLys: 0.769 ± 0.01	1.328TrpLeu: 1.328 ± 0.014	0.324TrpMet: 0.324 ± 0.008	0.499TrpAsn: 0.499 ± 0.009	0.597TrpPro: 0.597 ± 0.008	0.558TrpGln: 0.558 ± 0.01	0.796TrpArg: 0.796 ± 0.01	0.916TrpSer: 0.916 ± 0.012	0.725TrpThr: 0.725 ± 0.011	0.838TrpVal: 0.838 ± 0.01	0.205TrpTrp: 0.205 ± 0.006	0.351TrpTyr: 0.351 ± 0.007	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.425TyrAla: 1.425 ± 0.014	0.672TyrCys: 0.672 ± 0.01	1.249TyrAsp: 1.249 ± 0.014	1.522TyrGlu: 1.522 ± 0.019	1.212TyrPhe: 1.212 ± 0.011	1.631TyrGly: 1.631 ± 0.015	0.718TyrHis: 0.718 ± 0.011	1.226TyrIle: 1.226 ± 0.014	1.245TyrLys: 1.245 ± 0.021	2.644TyrLeu: 2.644 ± 0.021	0.572TyrMet: 0.572 ± 0.008	0.982TyrAsn: 0.982 ± 0.013	1.275TyrPro: 1.275 ± 0.014	1.183TyrGln: 1.183 ± 0.013	1.559TyrArg: 1.559 ± 0.017	2.091TyrSer: 2.091 ± 0.019	1.493TyrThr: 1.493 ± 0.017	1.655TyrVal: 1.655 ± 0.015	0.354TyrTrp: 0.354 ± 0.008	0.862TyrTyr: 0.862 ± 0.011	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.016XaaAla: 0.016 ± 0.001	0.002XaaCys: 0.002 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.005XaaGlu: 0.005 ± 0.001	0.001XaaPhe: 0.001 ± 0.0	0.016XaaGly: 0.016 ± 0.001	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.007XaaLeu: 0.007 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.014XaaPro: 0.014 ± 0.001	0.003XaaGln: 0.003 ± 0.001	0.011XaaArg: 0.011 ± 0.001	0.007XaaSer: 0.007 ± 0.001	0.003XaaThr: 0.003 ± 0.001	0.007XaaVal: 0.007 ± 0.001	0.002XaaTrp: 0.002 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	1.553XaaXaa: 1.553 ± 0.094

Statistics based on 20003 proteins (8746461 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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