Amino acid dipepetide frequency for Hubei tombus-like virus 27

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.65AlaAla: 5.65 ± 1.481
2.825AlaCys: 2.825 ± 0.74
1.412AlaAsp: 1.412 ± 1.505
0.0AlaGlu: 0.0 ± 0.0
2.825AlaPhe: 2.825 ± 3.009
0.0AlaGly: 0.0 ± 0.0
4.237AlaHis: 4.237 ± 0.024
9.887AlaIle: 9.887 ± 0.812
1.412AlaLys: 1.412 ± 0.764
2.825AlaLeu: 2.825 ± 3.009
0.0AlaMet: 0.0 ± 0.0
5.65AlaAsn: 5.65 ± 1.481
1.412AlaPro: 1.412 ± 0.764
2.825AlaGln: 2.825 ± 0.74
4.237AlaArg: 4.237 ± 0.024
2.825AlaSer: 2.825 ± 1.529
1.412AlaThr: 1.412 ± 1.505
4.237AlaVal: 4.237 ± 2.245
0.0AlaTrp: 0.0 ± 0.0
1.412AlaTyr: 1.412 ± 0.764
0.0AlaXaa: 0.0 ± 0.0
Cys
1.412CysAla: 1.412 ± 1.505
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
2.825CysPhe: 2.825 ± 0.74
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.412CysIle: 1.412 ± 1.505
1.412CysLys: 1.412 ± 1.505
1.412CysLeu: 1.412 ± 0.764
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.412CysArg: 1.412 ± 0.764
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
7.062AspAla: 7.062 ± 0.716
1.412AspCys: 1.412 ± 0.764
1.412AspAsp: 1.412 ± 0.764
5.65AspGlu: 5.65 ± 1.481
0.0AspPhe: 0.0 ± 0.0
1.412AspGly: 1.412 ± 0.764
2.825AspHis: 2.825 ± 1.529
4.237AspIle: 4.237 ± 2.245
4.237AspLys: 4.237 ± 2.245
4.237AspLeu: 4.237 ± 2.245
1.412AspMet: 1.412 ± 0.622
4.237AspAsn: 4.237 ± 0.024
4.237AspPro: 4.237 ± 2.293
0.0AspGln: 0.0 ± 0.0
2.825AspArg: 2.825 ± 1.529
2.825AspSer: 2.825 ± 1.529
4.237AspThr: 4.237 ± 2.245
1.412AspVal: 1.412 ± 0.764
0.0AspTrp: 0.0 ± 0.0
2.825AspTyr: 2.825 ± 0.74
0.0AspXaa: 0.0 ± 0.0
Glu
1.412GluAla: 1.412 ± 1.505
0.0GluCys: 0.0 ± 0.0
2.825GluAsp: 2.825 ± 0.74
4.237GluGlu: 4.237 ± 0.024
2.825GluPhe: 2.825 ± 0.74
0.0GluGly: 0.0 ± 0.0
2.825GluHis: 2.825 ± 1.529
4.237GluIle: 4.237 ± 2.293
4.237GluLys: 4.237 ± 0.024
1.412GluLeu: 1.412 ± 0.764
1.412GluMet: 1.412 ± 0.764
7.062GluAsn: 7.062 ± 2.985
1.412GluPro: 1.412 ± 0.764
0.0GluGln: 0.0 ± 0.0
8.475GluArg: 8.475 ± 4.49
9.887GluSer: 9.887 ± 0.812
1.412GluThr: 1.412 ± 0.764
2.825GluVal: 2.825 ± 1.529
0.0GluTrp: 0.0 ± 0.0
1.412GluTyr: 1.412 ± 0.764
0.0GluXaa: 0.0 ± 0.0
Phe
1.412PheAla: 1.412 ± 1.505
1.412PheCys: 1.412 ± 0.764
2.825PheAsp: 2.825 ± 1.529
1.412PheGlu: 1.412 ± 1.505
0.0PhePhe: 0.0 ± 0.0
2.825PheGly: 2.825 ± 0.74
1.412PheHis: 1.412 ± 1.505
8.475PheIle: 8.475 ± 0.048
2.825PheLys: 2.825 ± 0.74
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
2.825PheAsn: 2.825 ± 0.74
0.0PhePro: 0.0 ± 0.0
1.412PheGln: 1.412 ± 0.764
2.825PheArg: 2.825 ± 0.74
0.0PheSer: 0.0 ± 0.0
4.237PheThr: 4.237 ± 2.293
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
1.412PheTyr: 1.412 ± 0.764
0.0PheXaa: 0.0 ± 0.0
Gly
1.412GlyAla: 1.412 ± 1.505
0.0GlyCys: 0.0 ± 0.0
4.237GlyAsp: 4.237 ± 2.293
1.412GlyGlu: 1.412 ± 1.505
1.412GlyPhe: 1.412 ± 1.505
0.0GlyGly: 0.0 ± 0.0
1.412GlyHis: 1.412 ± 0.764
0.0GlyIle: 0.0 ± 0.0
5.65GlyLys: 5.65 ± 0.788
1.412GlyLeu: 1.412 ± 1.505
1.412GlyMet: 1.412 ± 0.764
2.825GlyAsn: 2.825 ± 1.529
1.412GlyPro: 1.412 ± 1.505
1.412GlyGln: 1.412 ± 1.505
1.412GlyArg: 1.412 ± 0.764
0.0GlySer: 0.0 ± 0.0
2.825GlyThr: 2.825 ± 1.529
0.0GlyVal: 0.0 ± 0.0
1.412GlyTrp: 1.412 ± 1.505
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
5.65HisAsp: 5.65 ± 0.788
1.412HisGlu: 1.412 ± 0.764
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
5.65HisIle: 5.65 ± 3.057
1.412HisLys: 1.412 ± 0.764
2.825HisLeu: 2.825 ± 0.74
1.412HisMet: 1.412 ± 0.489
2.825HisAsn: 2.825 ± 1.529
0.0HisPro: 0.0 ± 0.0
1.412HisGln: 1.412 ± 0.764
2.825HisArg: 2.825 ± 0.74
0.0HisSer: 0.0 ± 0.0
2.825HisThr: 2.825 ± 1.529
1.412HisVal: 1.412 ± 0.764
0.0HisTrp: 0.0 ± 0.0
2.825HisTyr: 2.825 ± 1.529
0.0HisXaa: 0.0 ± 0.0
Ile
7.062IleAla: 7.062 ± 1.553
0.0IleCys: 0.0 ± 0.0
7.062IleAsp: 7.062 ± 0.716
5.65IleGlu: 5.65 ± 0.788
1.412IlePhe: 1.412 ± 0.764
4.237IleGly: 4.237 ± 2.245
1.412IleHis: 1.412 ± 0.764
9.887IleIle: 9.887 ± 3.726
11.299IleLys: 11.299 ± 2.961
0.0IleLeu: 0.0 ± 0.0
4.237IleMet: 4.237 ± 2.293
9.887IleAsn: 9.887 ± 3.081
1.412IlePro: 1.412 ± 0.764
7.062IleGln: 7.062 ± 0.716
4.237IleArg: 4.237 ± 0.024
4.237IleSer: 4.237 ± 4.514
11.299IleThr: 11.299 ± 2.961
4.237IleVal: 4.237 ± 0.024
0.0IleTrp: 0.0 ± 0.0
4.237IleTyr: 4.237 ± 2.293
0.0IleXaa: 0.0 ± 0.0
Lys
5.65LysAla: 5.65 ± 1.481
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
2.825LysGlu: 2.825 ± 0.74
7.062LysPhe: 7.062 ± 1.553
2.825LysGly: 2.825 ± 1.529
4.237LysHis: 4.237 ± 2.293
4.237LysIle: 4.237 ± 2.293
5.65LysLys: 5.65 ± 0.788
8.475LysLeu: 8.475 ± 2.317
4.237LysMet: 4.237 ± 0.024
7.062LysAsn: 7.062 ± 1.553
5.65LysPro: 5.65 ± 1.481
0.0LysGln: 0.0 ± 0.0
5.65LysArg: 5.65 ± 3.057
5.65LysSer: 5.65 ± 0.788
8.475LysThr: 8.475 ± 4.49
4.237LysVal: 4.237 ± 2.293
1.412LysTrp: 1.412 ± 0.764
5.65LysTyr: 5.65 ± 0.788
0.0LysXaa: 0.0 ± 0.0
Leu
4.237LeuAla: 4.237 ± 2.293
0.0LeuCys: 0.0 ± 0.0
4.237LeuAsp: 4.237 ± 2.245
4.237LeuGlu: 4.237 ± 2.293
0.0LeuPhe: 0.0 ± 0.0
1.412LeuGly: 1.412 ± 1.505
1.412LeuHis: 1.412 ± 0.764
11.299LeuIle: 11.299 ± 1.577
7.062LeuLys: 7.062 ± 3.822
2.825LeuLeu: 2.825 ± 0.74
0.0LeuMet: 0.0 ± 0.0
11.299LeuAsn: 11.299 ± 5.23
1.412LeuPro: 1.412 ± 0.764
5.65LeuGln: 5.65 ± 1.481
4.237LeuArg: 4.237 ± 4.514
0.0LeuSer: 0.0 ± 0.0
2.825LeuThr: 2.825 ± 3.009
2.825LeuVal: 2.825 ± 0.74
0.0LeuTrp: 0.0 ± 0.0
1.412LeuTyr: 1.412 ± 0.764
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
1.412MetAsp: 1.412 ± 0.764
2.825MetGlu: 2.825 ± 0.74
2.825MetPhe: 2.825 ± 1.529
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.825MetLys: 2.825 ± 1.529
1.412MetLeu: 1.412 ± 1.505
4.237MetMet: 4.237 ± 0.024
1.412MetAsn: 1.412 ± 1.505
1.412MetPro: 1.412 ± 1.505
1.412MetGln: 1.412 ± 0.764
0.0MetArg: 0.0 ± 0.0
1.412MetSer: 1.412 ± 0.764
4.237MetThr: 4.237 ± 2.293
1.412MetVal: 1.412 ± 0.764
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.825AsnAla: 2.825 ± 3.009
0.0AsnCys: 0.0 ± 0.0
4.237AsnAsp: 4.237 ± 2.245
5.65AsnGlu: 5.65 ± 1.481
4.237AsnPhe: 4.237 ± 0.024
1.412AsnGly: 1.412 ± 0.764
4.237AsnHis: 4.237 ± 2.245
7.062AsnIle: 7.062 ± 1.553
8.475AsnLys: 8.475 ± 2.317
5.65AsnLeu: 5.65 ± 0.788
0.0AsnMet: 0.0 ± 0.0
5.65AsnAsn: 5.65 ± 0.788
0.0AsnPro: 0.0 ± 0.0
7.062AsnGln: 7.062 ± 0.716
5.65AsnArg: 5.65 ± 0.788
5.65AsnSer: 5.65 ± 3.057
2.825AsnThr: 2.825 ± 0.74
0.0AsnVal: 0.0 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
7.062AsnTyr: 7.062 ± 0.716
0.0AsnXaa: 0.0 ± 0.0
Pro
4.237ProAla: 4.237 ± 2.293
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
2.825ProGlu: 2.825 ± 1.529
0.0ProPhe: 0.0 ± 0.0
2.825ProGly: 2.825 ± 0.74
1.412ProHis: 1.412 ± 0.764
1.412ProIle: 1.412 ± 0.764
4.237ProLys: 4.237 ± 0.024
1.412ProLeu: 1.412 ± 0.764
0.0ProMet: 0.0 ± 0.0
1.412ProAsn: 1.412 ± 0.764
1.412ProPro: 1.412 ± 0.764
1.412ProGln: 1.412 ± 1.505
2.825ProArg: 2.825 ± 1.529
4.237ProSer: 4.237 ± 0.024
1.412ProThr: 1.412 ± 0.764
0.0ProVal: 0.0 ± 0.0
2.825ProTrp: 2.825 ± 0.74
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.825GlnAla: 2.825 ± 0.74
0.0GlnCys: 0.0 ± 0.0
2.825GlnAsp: 2.825 ± 1.529
4.237GlnGlu: 4.237 ± 2.245
1.412GlnPhe: 1.412 ± 1.505
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
2.825GlnIle: 2.825 ± 0.74
4.237GlnLys: 4.237 ± 2.293
4.237GlnLeu: 4.237 ± 0.024
1.412GlnMet: 1.412 ± 1.505
1.412GlnAsn: 1.412 ± 1.505
2.825GlnPro: 2.825 ± 1.529
2.825GlnGln: 2.825 ± 0.74
1.412GlnArg: 1.412 ± 1.505
0.0GlnSer: 0.0 ± 0.0
2.825GlnThr: 2.825 ± 1.529
1.412GlnVal: 1.412 ± 0.764
0.0GlnTrp: 0.0 ± 0.0
2.825GlnTyr: 2.825 ± 1.529
0.0GlnXaa: 0.0 ± 0.0
Arg
1.412ArgAla: 1.412 ± 1.505
0.0ArgCys: 0.0 ± 0.0
2.825ArgAsp: 2.825 ± 0.74
2.825ArgGlu: 2.825 ± 1.529
1.412ArgPhe: 1.412 ± 1.505
2.825ArgGly: 2.825 ± 0.74
2.825ArgHis: 2.825 ± 1.529
5.65ArgIle: 5.65 ± 1.481
4.237ArgLys: 4.237 ± 2.293
5.65ArgLeu: 5.65 ± 0.788
1.412ArgMet: 1.412 ± 0.764
2.825ArgAsn: 2.825 ± 0.74
1.412ArgPro: 1.412 ± 1.505
2.825ArgGln: 2.825 ± 1.529
0.0ArgArg: 0.0 ± 0.0
4.237ArgSer: 4.237 ± 2.245
11.299ArgThr: 11.299 ± 0.692
2.825ArgVal: 2.825 ± 1.529
0.0ArgTrp: 0.0 ± 0.0
4.237ArgTyr: 4.237 ± 0.024
0.0ArgXaa: 0.0 ± 0.0
Ser
1.412SerAla: 1.412 ± 1.505
0.0SerCys: 0.0 ± 0.0
2.825SerAsp: 2.825 ± 1.529
1.412SerGlu: 1.412 ± 0.764
1.412SerPhe: 1.412 ± 0.764
4.237SerGly: 4.237 ± 0.024
1.412SerHis: 1.412 ± 0.764
9.887SerIle: 9.887 ± 1.457
4.237SerLys: 4.237 ± 0.024
5.65SerLeu: 5.65 ± 0.788
0.0SerMet: 0.0 ± 0.0
1.412SerAsn: 1.412 ± 0.764
1.412SerPro: 1.412 ± 0.764
0.0SerGln: 0.0 ± 0.0
1.412SerArg: 1.412 ± 0.764
2.825SerSer: 2.825 ± 0.74
4.237SerThr: 4.237 ± 2.245
2.825SerVal: 2.825 ± 1.529
1.412SerTrp: 1.412 ± 0.764
2.825SerTyr: 2.825 ± 0.74
0.0SerXaa: 0.0 ± 0.0
Thr
1.412ThrAla: 1.412 ± 1.505
0.0ThrCys: 0.0 ± 0.0
4.237ThrAsp: 4.237 ± 2.245
5.65ThrGlu: 5.65 ± 3.057
1.412ThrPhe: 1.412 ± 0.764
2.825ThrGly: 2.825 ± 0.74
2.825ThrHis: 2.825 ± 1.529
8.475ThrIle: 8.475 ± 4.49
7.062ThrLys: 7.062 ± 1.553
7.062ThrLeu: 7.062 ± 5.254
2.825ThrMet: 2.825 ± 1.529
1.412ThrAsn: 1.412 ± 0.764
1.412ThrPro: 1.412 ± 0.764
0.0ThrGln: 0.0 ± 0.0
9.887ThrArg: 9.887 ± 0.812
4.237ThrSer: 4.237 ± 0.024
8.475ThrThr: 8.475 ± 4.49
7.062ThrVal: 7.062 ± 0.716
1.412ThrTrp: 1.412 ± 1.505
2.825ThrTyr: 2.825 ± 0.74
0.0ThrXaa: 0.0 ± 0.0
Val
1.412ValAla: 1.412 ± 0.764
0.0ValCys: 0.0 ± 0.0
5.65ValAsp: 5.65 ± 0.788
4.237ValGlu: 4.237 ± 0.024
1.412ValPhe: 1.412 ± 0.764
1.412ValGly: 1.412 ± 0.764
0.0ValHis: 0.0 ± 0.0
2.825ValIle: 2.825 ± 0.74
2.825ValLys: 2.825 ± 1.529
2.825ValLeu: 2.825 ± 0.74
0.0ValMet: 0.0 ± 0.0
5.65ValAsn: 5.65 ± 0.788
1.412ValPro: 1.412 ± 0.764
1.412ValGln: 1.412 ± 0.764
1.412ValArg: 1.412 ± 0.764
0.0ValSer: 0.0 ± 0.0
1.412ValThr: 1.412 ± 0.764
0.0ValVal: 0.0 ± 0.0
1.412ValTrp: 1.412 ± 1.505
2.825ValTyr: 2.825 ± 1.529
0.0ValXaa: 0.0 ± 0.0
Trp
1.412TrpAla: 1.412 ± 1.505
2.825TrpCys: 2.825 ± 3.009
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.412TrpPhe: 1.412 ± 0.764
0.0TrpGly: 0.0 ± 0.0
1.412TrpHis: 1.412 ± 0.764
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.412TrpMet: 1.412 ± 1.505
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
2.825TrpThr: 2.825 ± 1.529
0.0TrpVal: 0.0 ± 0.0
1.412TrpTrp: 1.412 ± 1.505
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.825TyrAla: 2.825 ± 1.529
1.412TyrCys: 1.412 ± 1.505
2.825TyrAsp: 2.825 ± 0.74
1.412TyrGlu: 1.412 ± 1.505
1.412TyrPhe: 1.412 ± 0.764
1.412TyrGly: 1.412 ± 0.764
0.0TyrHis: 0.0 ± 0.0
1.412TyrIle: 1.412 ± 1.505
5.65TyrLys: 5.65 ± 0.788
7.062TyrLeu: 7.062 ± 1.553
0.0TyrMet: 0.0 ± 0.0
2.825TyrAsn: 2.825 ± 1.529
5.65TyrPro: 5.65 ± 3.057
2.825TyrGln: 2.825 ± 1.529
0.0TyrArg: 0.0 ± 0.0
2.825TyrSer: 2.825 ± 1.529
1.412TyrThr: 1.412 ± 1.505
1.412TyrVal: 1.412 ± 0.764
1.412TyrTrp: 1.412 ± 0.764
4.237TyrTyr: 4.237 ± 2.293
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (709 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski