Amino acid dipepetide frequency for Citrus clementina (Clementine) (Citrus deliciosa x Citrus sinensis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.474AlaAla: 6.474 ± 0.034	1.308AlaCys: 1.308 ± 0.011	3.153AlaAsp: 3.153 ± 0.016	4.174AlaGlu: 4.174 ± 0.022	2.853AlaPhe: 2.853 ± 0.017	4.115AlaGly: 4.115 ± 0.022	1.285AlaHis: 1.285 ± 0.009	3.856AlaIle: 3.856 ± 0.021	3.911AlaLys: 3.911 ± 0.021	6.658AlaLeu: 6.658 ± 0.026	1.763AlaMet: 1.763 ± 0.012	2.689AlaAsn: 2.689 ± 0.015	2.701AlaPro: 2.701 ± 0.017	2.088AlaGln: 2.088 ± 0.014	3.339AlaArg: 3.339 ± 0.016	6.048AlaSer: 6.048 ± 0.025	3.576AlaThr: 3.576 ± 0.018	4.827AlaVal: 4.827 ± 0.022	0.772AlaTrp: 0.772 ± 0.008	1.838AlaTyr: 1.838 ± 0.012	0.0AlaXaa: 0.0 ± 0.0
Cys	0.994CysAla: 0.994 ± 0.009	0.565CysCys: 0.565 ± 0.007	0.895CysAsp: 0.895 ± 0.01	0.922CysGlu: 0.922 ± 0.01	0.954CysPhe: 0.954 ± 0.009	1.404CysGly: 1.404 ± 0.013	0.475CysHis: 0.475 ± 0.007	1.053CysIle: 1.053 ± 0.01	1.224CysLys: 1.224 ± 0.013	2.003CysLeu: 2.003 ± 0.014	0.462CysMet: 0.462 ± 0.006	0.906CysAsn: 0.906 ± 0.008	0.958CysPro: 0.958 ± 0.01	0.63CysGln: 0.63 ± 0.006	1.048CysArg: 1.048 ± 0.01	1.863CysSer: 1.863 ± 0.014	0.871CysThr: 0.871 ± 0.008	1.086CysVal: 1.086 ± 0.01	0.267CysTrp: 0.267 ± 0.004	0.58CysTyr: 0.58 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	3.453AspAla: 3.453 ± 0.018	1.004AspCys: 1.004 ± 0.01	3.569AspAsp: 3.569 ± 0.023	3.902AspGlu: 3.902 ± 0.02	2.381AspPhe: 2.381 ± 0.015	3.721AspGly: 3.721 ± 0.021	1.217AspHis: 1.217 ± 0.01	3.05AspIle: 3.05 ± 0.017	2.757AspLys: 2.757 ± 0.014	5.148AspLeu: 5.148 ± 0.024	1.295AspMet: 1.295 ± 0.01	2.154AspAsn: 2.154 ± 0.013	2.48AspPro: 2.48 ± 0.016	1.774AspGln: 1.774 ± 0.012	2.388AspArg: 2.388 ± 0.016	4.128AspSer: 4.128 ± 0.021	2.147AspThr: 2.147 ± 0.011	3.636AspVal: 3.636 ± 0.018	0.72AspTrp: 0.72 ± 0.009	1.592AspTyr: 1.592 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	4.688GluAla: 4.688 ± 0.024	0.949GluCys: 0.949 ± 0.009	3.817GluAsp: 3.817 ± 0.023	5.862GluGlu: 5.862 ± 0.04	2.422GluPhe: 2.422 ± 0.013	3.591GluGly: 3.591 ± 0.019	1.22GluHis: 1.22 ± 0.01	3.898GluIle: 3.898 ± 0.017	4.692GluLys: 4.692 ± 0.029	6.134GluLeu: 6.134 ± 0.026	1.75GluMet: 1.75 ± 0.014	3.158GluAsn: 3.158 ± 0.018	2.07GluPro: 2.07 ± 0.013	2.118GluGln: 2.118 ± 0.014	3.36GluArg: 3.36 ± 0.019	4.607GluSer: 4.607 ± 0.022	3.01GluThr: 3.01 ± 0.017	4.103GluVal: 4.103 ± 0.02	0.735GluTrp: 0.735 ± 0.008	1.641GluTyr: 1.641 ± 0.013	0.0GluXaa: 0.0 ± 0.0
Phe	2.587PheAla: 2.587 ± 0.016	0.979PheCys: 0.979 ± 0.01	2.47PheAsp: 2.47 ± 0.016	2.345PheGlu: 2.345 ± 0.012	2.085PhePhe: 2.085 ± 0.016	3.143PheGly: 3.143 ± 0.021	1.116PheHis: 1.116 ± 0.009	2.214PheIle: 2.214 ± 0.013	2.239PheLys: 2.239 ± 0.013	4.466PheLeu: 4.466 ± 0.02	0.972PheMet: 0.972 ± 0.008	1.909PheAsn: 1.909 ± 0.013	2.075PhePro: 2.075 ± 0.016	1.601PheGln: 1.601 ± 0.011	2.07PheArg: 2.07 ± 0.014	4.271PheSer: 4.271 ± 0.022	2.054PheThr: 2.054 ± 0.013	2.879PheVal: 2.879 ± 0.019	0.589PheTrp: 0.589 ± 0.007	1.351PheTyr: 1.351 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	3.78GlyAla: 3.78 ± 0.021	1.306GlyCys: 1.306 ± 0.011	3.315GlyAsp: 3.315 ± 0.017	3.571GlyGlu: 3.571 ± 0.019	3.206GlyPhe: 3.206 ± 0.018	4.925GlyGly: 4.925 ± 0.029	1.515GlyHis: 1.515 ± 0.013	3.694GlyIle: 3.694 ± 0.018	4.086GlyLys: 4.086 ± 0.016	5.987GlyLeu: 5.987 ± 0.025	1.507GlyMet: 1.507 ± 0.012	3.316GlyAsn: 3.316 ± 0.02	2.416GlyPro: 2.416 ± 0.016	2.118GlyGln: 2.118 ± 0.014	3.439GlyArg: 3.439 ± 0.021	5.896GlySer: 5.896 ± 0.029	3.204GlyThr: 3.204 ± 0.018	4.107GlyVal: 4.107 ± 0.02	0.872GlyTrp: 0.872 ± 0.009	2.079GlyTyr: 2.079 ± 0.017	0.0GlyXaa: 0.0 ± 0.0
His	1.4HisAla: 1.4 ± 0.012	0.548HisCys: 0.548 ± 0.006	1.135HisAsp: 1.135 ± 0.01	1.258HisGlu: 1.258 ± 0.01	1.104HisPhe: 1.104 ± 0.011	1.646HisGly: 1.646 ± 0.013	0.952HisHis: 0.952 ± 0.012	1.239HisIle: 1.239 ± 0.01	1.185HisLys: 1.185 ± 0.01	2.475HisLeu: 2.475 ± 0.016	0.535HisMet: 0.535 ± 0.006	1.017HisAsn: 1.017 ± 0.009	1.307HisPro: 1.307 ± 0.012	1.056HisGln: 1.056 ± 0.009	1.342HisArg: 1.342 ± 0.012	1.921HisSer: 1.921 ± 0.014	0.899HisThr: 0.899 ± 0.009	1.548HisVal: 1.548 ± 0.011	0.301HisTrp: 0.301 ± 0.004	0.72HisTyr: 0.72 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	3.646IleAla: 3.646 ± 0.016	1.183IleCys: 1.183 ± 0.01	2.99IleAsp: 2.99 ± 0.017	3.278IleGlu: 3.278 ± 0.015	2.463IlePhe: 2.463 ± 0.016	3.507IleGly: 3.507 ± 0.021	1.299IleHis: 1.299 ± 0.011	3.009IleIle: 3.009 ± 0.017	3.02IleLys: 3.02 ± 0.018	5.466IleLeu: 5.466 ± 0.022	1.156IleMet: 1.156 ± 0.01	2.362IleAsn: 2.362 ± 0.014	3.168IlePro: 3.168 ± 0.021	1.957IleGln: 1.957 ± 0.014	2.691IleArg: 2.691 ± 0.016	5.015IleSer: 5.015 ± 0.02	2.621IleThr: 2.621 ± 0.013	3.543IleVal: 3.543 ± 0.02	0.736IleTrp: 0.736 ± 0.008	1.558IleTyr: 1.558 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	4.074LysAla: 4.074 ± 0.021	1.026LysCys: 1.026 ± 0.009	3.211LysAsp: 3.211 ± 0.017	4.572LysGlu: 4.572 ± 0.026	2.379LysPhe: 2.379 ± 0.013	3.506LysGly: 3.506 ± 0.019	1.345LysHis: 1.345 ± 0.012	3.461LysIle: 3.461 ± 0.018	4.668LysLys: 4.668 ± 0.027	6.291LysLeu: 6.291 ± 0.022	1.524LysMet: 1.524 ± 0.011	2.822LysAsn: 2.822 ± 0.017	2.721LysPro: 2.721 ± 0.017	2.341LysGln: 2.341 ± 0.014	3.542LysArg: 3.542 ± 0.02	4.712LysSer: 4.712 ± 0.023	2.809LysThr: 2.809 ± 0.016	3.802LysVal: 3.802 ± 0.018	0.815LysTrp: 0.815 ± 0.008	1.666LysTyr: 1.666 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	6.632LeuAla: 6.632 ± 0.026	1.932LeuCys: 1.932 ± 0.015	5.234LeuAsp: 5.234 ± 0.024	6.458LeuGlu: 6.458 ± 0.034	4.055LeuPhe: 4.055 ± 0.024	5.842LeuGly: 5.842 ± 0.028	2.598LeuHis: 2.598 ± 0.015	4.883LeuIle: 4.883 ± 0.023	6.516LeuLys: 6.516 ± 0.028	10.177LeuLeu: 10.177 ± 0.039	2.177LeuMet: 2.177 ± 0.013	4.218LeuAsn: 4.218 ± 0.022	5.218LeuPro: 5.218 ± 0.027	4.433LeuGln: 4.433 ± 0.022	5.454LeuArg: 5.454 ± 0.022	9.0LeuSer: 9.0 ± 0.046	4.57LeuThr: 4.57 ± 0.022	6.401LeuVal: 6.401 ± 0.025	1.179LeuTrp: 1.179 ± 0.011	2.608LeuTyr: 2.608 ± 0.015	0.0LeuXaa: 0.0 ± 0.0
Met	2.103MetAla: 2.103 ± 0.014	0.329MetCys: 0.329 ± 0.006	1.358MetAsp: 1.358 ± 0.01	1.89MetGlu: 1.89 ± 0.013	0.818MetPhe: 0.818 ± 0.008	1.623MetGly: 1.623 ± 0.015	0.56MetHis: 0.56 ± 0.007	1.245MetIle: 1.245 ± 0.011	1.645MetLys: 1.645 ± 0.011	2.181MetLeu: 2.181 ± 0.013	0.686MetMet: 0.686 ± 0.008	1.052MetAsn: 1.052 ± 0.01	1.067MetPro: 1.067 ± 0.01	0.962MetGln: 0.962 ± 0.009	1.166MetArg: 1.166 ± 0.01	1.733MetSer: 1.733 ± 0.011	1.016MetThr: 1.016 ± 0.009	1.55MetVal: 1.55 ± 0.01	0.268MetTrp: 0.268 ± 0.004	0.58MetTyr: 0.58 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.71AsnAla: 2.71 ± 0.017	0.942AsnCys: 0.942 ± 0.01	2.182AsnAsp: 2.182 ± 0.015	2.632AsnGlu: 2.632 ± 0.017	2.188AsnPhe: 2.188 ± 0.016	3.328AsnGly: 3.328 ± 0.017	1.12AsnHis: 1.12 ± 0.01	2.596AsnIle: 2.596 ± 0.016	2.596AsnLys: 2.596 ± 0.014	5.123AsnLeu: 5.123 ± 0.036	1.103AsnMet: 1.103 ± 0.01	2.732AsnAsn: 2.732 ± 0.027	2.338AsnPro: 2.338 ± 0.016	1.806AsnGln: 1.806 ± 0.013	2.088AsnArg: 2.088 ± 0.015	4.07AsnSer: 4.07 ± 0.02	1.924AsnThr: 1.924 ± 0.013	2.858AsnVal: 2.858 ± 0.018	0.583AsnTrp: 0.583 ± 0.008	1.381AsnTyr: 1.381 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	3.03ProAla: 3.03 ± 0.023	0.768ProCys: 0.768 ± 0.008	2.431ProAsp: 2.431 ± 0.014	3.146ProGlu: 3.146 ± 0.016	2.012ProPhe: 2.012 ± 0.013	2.662ProGly: 2.662 ± 0.018	1.098ProHis: 1.098 ± 0.01	2.313ProIle: 2.313 ± 0.014	2.7ProLys: 2.7 ± 0.019	4.263ProLeu: 4.263 ± 0.02	0.921ProMet: 0.921 ± 0.009	2.313ProAsn: 2.313 ± 0.014	3.483ProPro: 3.483 ± 0.039	1.786ProGln: 1.786 ± 0.014	2.292ProArg: 2.292 ± 0.014	4.963ProSer: 4.963 ± 0.024	2.478ProThr: 2.478 ± 0.014	3.099ProVal: 3.099 ± 0.018	0.582ProTrp: 0.582 ± 0.009	1.292ProTyr: 1.292 ± 0.013	0.0ProXaa: 0.0 ± 0.0
Gln	2.353GlnAla: 2.353 ± 0.015	0.584GlnCys: 0.584 ± 0.006	1.65GlnAsp: 1.65 ± 0.012	2.413GlnGlu: 2.413 ± 0.016	1.437GlnPhe: 1.437 ± 0.011	2.072GlnGly: 2.072 ± 0.013	0.944GlnHis: 0.944 ± 0.009	2.07GlnIle: 2.07 ± 0.013	2.335GlnLys: 2.335 ± 0.017	3.833GlnLeu: 3.833 ± 0.019	0.991GlnMet: 0.991 ± 0.009	1.919GlnAsn: 1.919 ± 0.013	1.707GlnPro: 1.707 ± 0.014	2.176GlnGln: 2.176 ± 0.033	2.118GlnArg: 2.118 ± 0.014	2.899GlnSer: 2.899 ± 0.019	1.688GlnThr: 1.688 ± 0.013	2.386GlnVal: 2.386 ± 0.014	0.446GlnTrp: 0.446 ± 0.006	0.931GlnTyr: 0.931 ± 0.009	0.0GlnXaa: 0.0 ± 0.0
Arg	3.236ArgAla: 3.236 ± 0.018	0.947ArgCys: 0.947 ± 0.009	2.632ArgAsp: 2.632 ± 0.018	3.328ArgGlu: 3.328 ± 0.02	2.23ArgPhe: 2.23 ± 0.013	3.114ArgGly: 3.114 ± 0.019	1.287ArgHis: 1.287 ± 0.012	2.928ArgIle: 2.928 ± 0.017	3.67ArgLys: 3.67 ± 0.02	5.083ArgLeu: 5.083 ± 0.021	1.269ArgMet: 1.269 ± 0.01	2.551ArgAsn: 2.551 ± 0.016	2.254ArgPro: 2.254 ± 0.016	1.864ArgGln: 1.864 ± 0.012	3.752ArgArg: 3.752 ± 0.021	4.217ArgSer: 4.217 ± 0.024	2.397ArgThr: 2.397 ± 0.013	3.265ArgVal: 3.265 ± 0.017	0.712ArgTrp: 0.712 ± 0.008	1.445ArgTyr: 1.445 ± 0.011	0.0ArgXaa: 0.0 ± 0.0
Ser	5.452SerAla: 5.452 ± 0.025	1.785SerCys: 1.785 ± 0.014	4.296SerAsp: 4.296 ± 0.022	4.752SerGlu: 4.752 ± 0.028	4.149SerPhe: 4.149 ± 0.023	5.881SerGly: 5.881 ± 0.027	2.025SerHis: 2.025 ± 0.012	4.667SerIle: 4.667 ± 0.021	5.011SerLys: 5.011 ± 0.024	8.991SerLeu: 8.991 ± 0.039	2.052SerMet: 2.052 ± 0.013	4.278SerAsn: 4.278 ± 0.021	4.293SerPro: 4.293 ± 0.026	3.057SerGln: 3.057 ± 0.019	4.435SerArg: 4.435 ± 0.023	10.986SerSer: 10.986 ± 0.054	4.53SerThr: 4.53 ± 0.022	5.328SerVal: 5.328 ± 0.025	1.17SerTrp: 1.17 ± 0.01	2.349SerTyr: 2.349 ± 0.015	0.0SerXaa: 0.0 ± 0.0
Thr	3.451ThrAla: 3.451 ± 0.017	0.942ThrCys: 0.942 ± 0.009	2.245ThrAsp: 2.245 ± 0.012	2.783ThrGlu: 2.783 ± 0.018	2.03ThrPhe: 2.03 ± 0.014	3.248ThrGly: 3.248 ± 0.018	1.033ThrHis: 1.033 ± 0.009	2.725ThrIle: 2.725 ± 0.015	2.626ThrLys: 2.626 ± 0.015	4.633ThrLeu: 4.633 ± 0.022	1.097ThrMet: 1.097 ± 0.01	2.097ThrAsn: 2.097 ± 0.013	2.428ThrPro: 2.428 ± 0.016	1.502ThrGln: 1.502 ± 0.012	2.302ThrArg: 2.302 ± 0.013	4.469ThrSer: 4.469 ± 0.022	2.799ThrThr: 2.799 ± 0.019	3.327ThrVal: 3.327 ± 0.018	0.631ThrTrp: 0.631 ± 0.008	1.36ThrTyr: 1.36 ± 0.011	0.0ThrXaa: 0.0 ± 0.0
Val	4.776ValAla: 4.776 ± 0.025	1.171ValCys: 1.171 ± 0.009	3.69ValAsp: 3.69 ± 0.019	4.179ValGlu: 4.179 ± 0.02	2.746ValPhe: 2.746 ± 0.016	4.145ValGly: 4.145 ± 0.022	1.494ValHis: 1.494 ± 0.012	3.536ValIle: 3.536 ± 0.02	3.907ValLys: 3.907 ± 0.018	6.499ValLeu: 6.499 ± 0.023	1.495ValMet: 1.495 ± 0.012	2.742ValAsn: 2.742 ± 0.015	3.174ValPro: 3.174 ± 0.018	2.274ValGln: 2.274 ± 0.015	3.07ValArg: 3.07 ± 0.017	5.463ValSer: 5.463 ± 0.023	3.244ValThr: 3.244 ± 0.015	4.738ValVal: 4.738 ± 0.023	0.761ValTrp: 0.761 ± 0.009	1.944ValTyr: 1.944 ± 0.014	0.0ValXaa: 0.0 ± 0.0
Trp	0.779TrpAla: 0.779 ± 0.007	0.238TrpCys: 0.238 ± 0.004	0.679TrpAsp: 0.679 ± 0.007	0.771TrpGlu: 0.771 ± 0.008	0.561TrpPhe: 0.561 ± 0.008	0.75TrpGly: 0.75 ± 0.008	0.296TrpHis: 0.296 ± 0.005	0.723TrpIle: 0.723 ± 0.008	0.953TrpLys: 0.953 ± 0.009	1.294TrpLeu: 1.294 ± 0.01	0.337TrpMet: 0.337 ± 0.005	0.699TrpAsn: 0.699 ± 0.009	0.498TrpPro: 0.498 ± 0.005	0.462TrpGln: 0.462 ± 0.006	0.816TrpArg: 0.816 ± 0.008	0.939TrpSer: 0.939 ± 0.009	0.62TrpThr: 0.62 ± 0.007	0.789TrpVal: 0.789 ± 0.008	0.233TrpTrp: 0.233 ± 0.005	0.341TrpTyr: 0.341 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.811TyrAla: 1.811 ± 0.013	0.657TyrCys: 0.657 ± 0.008	1.566TyrAsp: 1.566 ± 0.014	1.586TyrGlu: 1.586 ± 0.012	1.342TyrPhe: 1.342 ± 0.011	2.118TyrGly: 2.118 ± 0.015	0.712TyrHis: 0.712 ± 0.008	1.503TyrIle: 1.503 ± 0.01	1.546TyrLys: 1.546 ± 0.011	2.88TyrLeu: 2.88 ± 0.016	0.74TyrMet: 0.74 ± 0.008	1.364TyrAsn: 1.364 ± 0.011	1.278TyrPro: 1.278 ± 0.01	0.944TyrGln: 0.944 ± 0.008	1.469TyrArg: 1.469 ± 0.012	2.286TyrSer: 2.286 ± 0.014	1.271TyrThr: 1.271 ± 0.011	1.779TyrVal: 1.779 ± 0.014	0.405TyrTrp: 0.405 ± 0.006	0.995TyrTyr: 0.995 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 31273 proteins (12651335 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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