Human papillomavirus 139

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 7

Average proteome isoelectric point is 6.13

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|I6MRE3|I6MRE3_9PAPI Replication protein E1 OS=Human papillomavirus 139 OX=1070412 GN=E1 PE=3 SV=1
MM1 pKa = 7.49HH2 pKa = 7.47GEE4 pKa = 4.01VPDD7 pKa = 3.68IKK9 pKa = 11.03DD10 pKa = 3.46VILEE14 pKa = 4.02NLEE17 pKa = 4.84DD18 pKa = 5.5LILPANLLSDD28 pKa = 3.99EE29 pKa = 4.76DD30 pKa = 4.19LSAEE34 pKa = 4.16AEE36 pKa = 4.23LEE38 pKa = 4.34SAHH41 pKa = 5.35VLYY44 pKa = 10.8RR45 pKa = 11.84IVTYY49 pKa = 6.89CHH51 pKa = 6.63CGTRR55 pKa = 11.84IKK57 pKa = 10.66FSVLASPEE65 pKa = 4.29GIRR68 pKa = 11.84GLEE71 pKa = 3.85LLLLEE76 pKa = 4.73EE77 pKa = 4.77VSFLCTGCSKK87 pKa = 10.94GLNNGRR93 pKa = 3.95

Molecular weight: 10.21 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|I6MRE5|I6MRE5_9PAPI Uncharacterized protein (Fragment) OS=Human papillomavirus 139 OX=1070412 GN=E4 PE=4 SV=1
MM1 pKa = 6.94EE2 pKa = 4.99TLNEE6 pKa = 4.24RR7 pKa = 11.84YY8 pKa = 9.3DD9 pKa = 3.75ALQEE13 pKa = 4.0NLLMLYY19 pKa = 9.85EE20 pKa = 4.8AGSDD24 pKa = 4.08KK25 pKa = 10.79IDD27 pKa = 3.73DD28 pKa = 4.01QIMYY32 pKa = 8.91WDD34 pKa = 3.98IMRR37 pKa = 11.84QEE39 pKa = 4.13NVLFYY44 pKa = 9.99YY45 pKa = 10.48ARR47 pKa = 11.84KK48 pKa = 10.04KK49 pKa = 10.43NIARR53 pKa = 11.84IGLQPVPSLTTSEE66 pKa = 4.88HH67 pKa = 6.17KK68 pKa = 10.68AKK70 pKa = 10.06QAIMMSLQLKK80 pKa = 7.54SLKK83 pKa = 9.52MSAYY87 pKa = 9.9GKK89 pKa = 10.05EE90 pKa = 3.89PWTLQDD96 pKa = 3.25TSFEE100 pKa = 4.48VYY102 pKa = 9.96NAAPFNTFKK111 pKa = 10.87KK112 pKa = 10.42GAFTVDD118 pKa = 2.58VFYY121 pKa = 11.15DD122 pKa = 3.89DD123 pKa = 6.53DD124 pKa = 4.21EE125 pKa = 6.68DD126 pKa = 3.97NYY128 pKa = 11.36YY129 pKa = 10.15PYY131 pKa = 9.83TAWSFIYY138 pKa = 10.56YY139 pKa = 10.32EE140 pKa = 4.35NGDD143 pKa = 3.95GRR145 pKa = 11.84WHH147 pKa = 6.17KK148 pKa = 11.25VEE150 pKa = 4.13GQADD154 pKa = 3.86YY155 pKa = 11.11EE156 pKa = 4.14GLYY159 pKa = 10.48FISHH163 pKa = 7.16DD164 pKa = 3.79NEE166 pKa = 3.49KK167 pKa = 10.79NYY169 pKa = 10.86YY170 pKa = 8.23VTFDD174 pKa = 3.04TDD176 pKa = 3.04APRR179 pKa = 11.84FSRR182 pKa = 11.84TGHH185 pKa = 4.67WTVKK189 pKa = 10.1YY190 pKa = 9.79KK191 pKa = 10.9NHH193 pKa = 6.95TISSTSVTSTSGNPAGDD210 pKa = 3.53PSSRR214 pKa = 11.84EE215 pKa = 3.85GTNTVGQEE223 pKa = 4.32TPVSQTNRR231 pKa = 11.84RR232 pKa = 11.84RR233 pKa = 11.84QRR235 pKa = 11.84EE236 pKa = 4.2SSSSPNRR243 pKa = 11.84RR244 pKa = 11.84TRR246 pKa = 11.84QTTSQSDD253 pKa = 3.62WDD255 pKa = 4.3PDD257 pKa = 3.67SSPSSGEE264 pKa = 3.48RR265 pKa = 11.84LPRR268 pKa = 11.84RR269 pKa = 11.84RR270 pKa = 11.84RR271 pKa = 11.84RR272 pKa = 11.84RR273 pKa = 11.84EE274 pKa = 3.29RR275 pKa = 11.84APAAKK280 pKa = 9.72RR281 pKa = 11.84RR282 pKa = 11.84EE283 pKa = 4.07QRR285 pKa = 11.84KK286 pKa = 6.78STKK289 pKa = 10.42SLVPSPEE296 pKa = 3.95EE297 pKa = 3.35VGRR300 pKa = 11.84RR301 pKa = 11.84HH302 pKa = 6.36KK303 pKa = 10.82LVEE306 pKa = 4.26GKK308 pKa = 10.35GLSRR312 pKa = 11.84LRR314 pKa = 11.84RR315 pKa = 11.84LQEE318 pKa = 4.04EE319 pKa = 4.15AWDD322 pKa = 4.07PPVLLLKK329 pKa = 10.96GPANTLKK336 pKa = 10.55CYY338 pKa = 10.28RR339 pKa = 11.84YY340 pKa = 9.59RR341 pKa = 11.84CKK343 pKa = 10.23PRR345 pKa = 11.84CKK347 pKa = 10.51GLFTRR352 pKa = 11.84MSTVFSWVGEE362 pKa = 3.86GSEE365 pKa = 5.42RR366 pKa = 11.84IGQPRR371 pKa = 11.84MLLAFANNEE380 pKa = 3.84QRR382 pKa = 11.84RR383 pKa = 11.84HH384 pKa = 6.14FINTVHH390 pKa = 6.53LPKK393 pKa = 10.15GTEE396 pKa = 3.88YY397 pKa = 11.24SLGRR401 pKa = 11.84LDD403 pKa = 4.6SLL405 pKa = 4.66

Molecular weight: 46.98 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2426

93

617

346.6

38.93

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.73 ± 0.414

2.102 ± 0.754

6.595 ± 0.404

6.183 ± 0.692

4.534 ± 0.478

5.771 ± 0.621

1.855 ± 0.183

4.864 ± 0.571

5.111 ± 0.94

8.862 ± 0.677

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.649 ± 0.316

5.276 ± 0.38

5.894 ± 0.954

4.122 ± 0.55

5.936 ± 1.161

8.45 ± 0.509

6.183 ± 0.614

6.636 ± 0.721

1.237 ± 0.279

3.009 ± 0.5
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski