Amino acid dipepetide frequency for Wuhan Mosquito Virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.045AlaAla: 6.045 ± 3.525
1.273AlaCys: 1.273 ± 0.603
1.591AlaAsp: 1.591 ± 0.929
5.091AlaGlu: 5.091 ± 1.35
2.227AlaPhe: 2.227 ± 0.22
2.864AlaGly: 2.864 ± 1.271
0.318AlaHis: 0.318 ± 0.18
3.818AlaIle: 3.818 ± 1.326
3.5AlaLys: 3.5 ± 1.292
4.136AlaLeu: 4.136 ± 1.041
1.909AlaMet: 1.909 ± 0.637
0.955AlaAsn: 0.955 ± 0.441
1.273AlaPro: 1.273 ± 0.447
3.182AlaGln: 3.182 ± 0.562
3.182AlaArg: 3.182 ± 0.955
4.136AlaSer: 4.136 ± 1.133
5.091AlaThr: 5.091 ± 0.779
2.864AlaVal: 2.864 ± 1.82
0.318AlaTrp: 0.318 ± 0.18
2.545AlaTyr: 2.545 ± 0.361
0.0AlaXaa: 0.0 ± 0.0
Cys
0.955CysAla: 0.955 ± 0.709
0.0CysCys: 0.0 ± 0.0
2.545CysAsp: 2.545 ± 1.354
0.636CysGlu: 0.636 ± 0.301
0.955CysPhe: 0.955 ± 0.264
0.636CysGly: 0.636 ± 0.301
0.318CysHis: 0.318 ± 0.18
1.591CysIle: 1.591 ± 0.52
2.864CysLys: 2.864 ± 1.135
1.591CysLeu: 1.591 ± 0.471
0.0CysMet: 0.0 ± 0.0
1.273CysAsn: 1.273 ± 0.603
0.318CysPro: 0.318 ± 0.18
0.636CysGln: 0.636 ± 0.301
0.955CysArg: 0.955 ± 0.709
2.545CysSer: 2.545 ± 0.792
1.591CysThr: 1.591 ± 1.544
1.591CysVal: 1.591 ± 0.735
0.636CysTrp: 0.636 ± 0.84
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.5AspAla: 3.5 ± 0.874
0.636AspCys: 0.636 ± 0.503
4.454AspAsp: 4.454 ± 0.519
1.591AspGlu: 1.591 ± 0.899
4.454AspPhe: 4.454 ± 0.849
2.545AspGly: 2.545 ± 0.782
2.227AspHis: 2.227 ± 1.259
4.773AspIle: 4.773 ± 1.915
3.182AspLys: 3.182 ± 0.61
4.773AspLeu: 4.773 ± 0.795
1.909AspMet: 1.909 ± 0.561
4.454AspAsn: 4.454 ± 1.157
2.227AspPro: 2.227 ± 0.22
1.273AspGln: 1.273 ± 0.914
3.182AspArg: 3.182 ± 1.075
3.5AspSer: 3.5 ± 1.311
1.273AspThr: 1.273 ± 0.603
4.454AspVal: 4.454 ± 0.991
0.955AspTrp: 0.955 ± 0.54
1.909AspTyr: 1.909 ± 0.629
0.0AspXaa: 0.0 ± 0.0
Glu
5.409GluAla: 5.409 ± 2.603
0.955GluCys: 0.955 ± 0.264
3.818GluAsp: 3.818 ± 1.051
4.136GluGlu: 4.136 ± 0.856
1.909GluPhe: 1.909 ± 1.079
3.818GluGly: 3.818 ± 1.671
0.636GluHis: 0.636 ± 0.36
2.227GluIle: 2.227 ± 0.22
4.136GluLys: 4.136 ± 1.849
6.045GluLeu: 6.045 ± 1.224
1.909GluMet: 1.909 ± 0.529
2.864GluAsn: 2.864 ± 0.526
2.227GluPro: 2.227 ± 0.946
1.909GluGln: 1.909 ± 0.637
2.864GluArg: 2.864 ± 0.618
6.363GluSer: 6.363 ± 0.977
3.182GluThr: 3.182 ± 1.177
6.363GluVal: 6.363 ± 0.977
0.636GluTrp: 0.636 ± 0.781
1.909GluTyr: 1.909 ± 1.079
0.0GluXaa: 0.0 ± 0.0
Phe
0.955PheAla: 0.955 ± 1.108
1.273PheCys: 1.273 ± 0.337
0.955PheAsp: 0.955 ± 0.54
4.136PheGlu: 4.136 ± 0.357
0.955PhePhe: 0.955 ± 0.441
1.273PheGly: 1.273 ± 1.006
0.318PheHis: 0.318 ± 0.18
3.5PheIle: 3.5 ± 1.494
2.227PheLys: 2.227 ± 0.771
3.818PheLeu: 3.818 ± 1.326
0.955PheMet: 0.955 ± 0.54
1.591PheAsn: 1.591 ± 0.281
1.591PhePro: 1.591 ± 0.471
0.636PheGln: 0.636 ± 0.36
1.273PheArg: 1.273 ± 0.337
3.5PheSer: 3.5 ± 0.361
1.591PheThr: 1.591 ± 0.281
1.273PheVal: 1.273 ± 0.447
0.636PheTrp: 0.636 ± 0.503
0.318PheTyr: 0.318 ± 0.18
0.0PheXaa: 0.0 ± 0.0
Gly
1.909GlyAla: 1.909 ± 0.893
2.545GlyCys: 2.545 ± 2.25
3.818GlyAsp: 3.818 ± 1.011
2.864GlyGlu: 2.864 ± 1.462
2.864GlyPhe: 2.864 ± 0.799
3.5GlyGly: 3.5 ± 0.776
0.636GlyHis: 0.636 ± 0.503
1.591GlyIle: 1.591 ± 0.471
5.091GlyLys: 5.091 ± 0.723
4.454GlyLeu: 4.454 ± 0.441
2.864GlyMet: 2.864 ± 0.526
2.864GlyAsn: 2.864 ± 0.618
0.955GlyPro: 0.955 ± 0.607
3.182GlyGln: 3.182 ± 0.562
2.545GlyArg: 2.545 ± 0.967
4.454GlySer: 4.454 ± 0.762
6.363GlyThr: 6.363 ± 1.529
3.182GlyVal: 3.182 ± 0.489
0.955GlyTrp: 0.955 ± 0.54
1.273GlyTyr: 1.273 ± 1.125
0.0GlyXaa: 0.0 ± 0.0
His
0.955HisAla: 0.955 ± 0.441
0.0HisCys: 0.0 ± 0.0
1.273HisAsp: 1.273 ± 0.437
1.591HisGlu: 1.591 ± 0.281
0.0HisPhe: 0.0 ± 0.0
0.318HisGly: 0.318 ± 0.18
0.636HisHis: 0.636 ± 0.36
1.273HisIle: 1.273 ± 0.447
1.591HisLys: 1.591 ± 0.899
1.909HisLeu: 1.909 ± 1.079
0.318HisMet: 0.318 ± 0.18
2.227HisAsn: 2.227 ± 0.87
0.318HisPro: 0.318 ± 0.18
1.591HisGln: 1.591 ± 0.537
1.273HisArg: 1.273 ± 0.337
1.909HisSer: 1.909 ± 1.079
1.273HisThr: 1.273 ± 0.719
1.591HisVal: 1.591 ± 0.471
0.636HisTrp: 0.636 ± 0.503
1.273HisTyr: 1.273 ± 0.603
0.0HisXaa: 0.0 ± 0.0
Ile
3.5IleAla: 3.5 ± 1.466
0.955IleCys: 0.955 ± 0.709
4.454IleAsp: 4.454 ± 1.377
3.818IleGlu: 3.818 ± 1.671
0.955IlePhe: 0.955 ± 1.26
4.773IleGly: 4.773 ± 0.795
2.864IleHis: 2.864 ± 0.713
4.454IleIle: 4.454 ± 1.377
5.727IleLys: 5.727 ± 1.156
4.773IleLeu: 4.773 ± 1.755
4.454IleMet: 4.454 ± 0.628
3.182IleAsn: 3.182 ± 0.489
1.909IlePro: 1.909 ± 0.629
1.909IleGln: 1.909 ± 0.637
3.5IleArg: 3.5 ± 0.909
6.682IleSer: 6.682 ± 3.126
4.773IleThr: 4.773 ± 1.098
4.136IleVal: 4.136 ± 0.715
0.955IleTrp: 0.955 ± 0.709
3.182IleTyr: 3.182 ± 1.262
0.0IleXaa: 0.0 ± 0.0
Lys
4.136LysAla: 4.136 ± 1.148
1.909LysCys: 1.909 ± 0.557
2.545LysAsp: 2.545 ± 1.364
5.727LysGlu: 5.727 ± 1.611
1.909LysPhe: 1.909 ± 0.557
3.182LysGly: 3.182 ± 0.192
3.5LysHis: 3.5 ± 0.387
3.818LysIle: 3.818 ± 0.784
4.454LysLys: 4.454 ± 2.273
7.318LysLeu: 7.318 ± 0.93
2.227LysMet: 2.227 ± 0.578
3.182LysAsn: 3.182 ± 1.262
2.545LysPro: 2.545 ± 0.674
3.5LysGln: 3.5 ± 1.311
3.818LysArg: 3.818 ± 0.74
4.454LysSer: 4.454 ± 1.742
3.182LysThr: 3.182 ± 0.192
5.091LysVal: 5.091 ± 0.421
0.636LysTrp: 0.636 ± 0.301
4.454LysTyr: 4.454 ± 2.518
0.0LysXaa: 0.0 ± 0.0
Leu
5.409LeuAla: 5.409 ± 0.741
2.227LeuCys: 2.227 ± 0.22
6.363LeuAsp: 6.363 ± 0.374
6.363LeuGlu: 6.363 ± 1.141
2.227LeuPhe: 2.227 ± 1.259
5.409LeuGly: 5.409 ± 0.741
1.909LeuHis: 1.909 ± 0.177
4.454LeuIle: 4.454 ± 0.849
6.045LeuLys: 6.045 ± 2.303
6.363LeuLeu: 6.363 ± 0.851
2.227LeuMet: 2.227 ± 0.22
4.773LeuAsn: 4.773 ± 1.682
4.136LeuPro: 4.136 ± 1.602
2.227LeuGln: 2.227 ± 0.381
4.136LeuArg: 4.136 ± 0.357
4.773LeuSer: 4.773 ± 0.097
4.773LeuThr: 4.773 ± 0.589
2.864LeuVal: 2.864 ± 0.526
0.955LeuTrp: 0.955 ± 0.54
3.5LeuTyr: 3.5 ± 1.051
0.0LeuXaa: 0.0 ± 0.0
Met
1.273MetAla: 1.273 ± 0.603
0.636MetCys: 0.636 ± 0.301
0.955MetAsp: 0.955 ± 0.54
1.273MetGlu: 1.273 ± 0.447
1.909MetPhe: 1.909 ± 0.177
0.955MetGly: 0.955 ± 1.26
0.955MetHis: 0.955 ± 0.54
3.818MetIle: 3.818 ± 0.74
0.955MetLys: 0.955 ± 0.441
3.182MetLeu: 3.182 ± 0.699
1.273MetMet: 1.273 ± 0.337
1.591MetAsn: 1.591 ± 0.281
2.864MetPro: 2.864 ± 0.793
0.318MetGln: 0.318 ± 0.18
1.273MetArg: 1.273 ± 1.006
4.136MetSer: 4.136 ± 1.327
2.545MetThr: 2.545 ± 0.967
2.545MetVal: 2.545 ± 0.967
0.318MetTrp: 0.318 ± 0.42
0.955MetTyr: 0.955 ± 0.709
0.0MetXaa: 0.0 ± 0.0
Asn
2.227AsnAla: 2.227 ± 0.771
1.273AsnCys: 1.273 ± 0.337
3.818AsnAsp: 3.818 ± 1.274
2.545AsnGlu: 2.545 ± 0.211
0.318AsnPhe: 0.318 ± 0.18
5.727AsnGly: 5.727 ± 2.269
0.636AsnHis: 0.636 ± 1.228
2.864AsnIle: 2.864 ± 0.091
4.136AsnLys: 4.136 ± 0.715
4.454AsnLeu: 4.454 ± 0.246
1.591AsnMet: 1.591 ± 0.662
2.864AsnAsn: 2.864 ± 0.713
0.955AsnPro: 0.955 ± 0.709
1.909AsnGln: 1.909 ± 1.115
3.182AsnArg: 3.182 ± 1.262
1.909AsnSer: 1.909 ± 1.079
3.182AsnThr: 3.182 ± 0.834
6.363AsnVal: 6.363 ± 0.782
1.273AsnTrp: 1.273 ± 0.447
3.182AsnTyr: 3.182 ± 0.834
0.0AsnXaa: 0.0 ± 0.0
Pro
0.955ProAla: 0.955 ± 0.54
0.318ProCys: 0.318 ± 0.18
1.273ProAsp: 1.273 ± 0.719
4.773ProGlu: 4.773 ± 1.755
2.227ProPhe: 2.227 ± 0.778
1.591ProGly: 1.591 ± 0.735
0.0ProHis: 0.0 ± 0.0
2.864ProIle: 2.864 ± 0.526
2.545ProLys: 2.545 ± 0.782
1.591ProLeu: 1.591 ± 1.287
0.636ProMet: 0.636 ± 0.36
2.227ProAsn: 2.227 ± 0.22
2.227ProPro: 2.227 ± 1.259
0.318ProGln: 0.318 ± 0.18
1.909ProArg: 1.909 ± 0.529
3.182ProSer: 3.182 ± 0.489
2.545ProThr: 2.545 ± 0.361
2.227ProVal: 2.227 ± 0.381
0.318ProTrp: 0.318 ± 0.18
0.955ProTyr: 0.955 ± 0.264
0.0ProXaa: 0.0 ± 0.0
Gln
2.864GlnAla: 2.864 ± 0.713
0.0GlnCys: 0.0 ± 0.0
2.227GlnAsp: 2.227 ± 0.796
1.273GlnGlu: 1.273 ± 0.437
1.591GlnPhe: 1.591 ± 1.608
3.5GlnGly: 3.5 ± 0.361
0.318GlnHis: 0.318 ± 0.18
2.545GlnIle: 2.545 ± 0.211
1.273GlnLys: 1.273 ± 0.447
2.864GlnLeu: 2.864 ± 1.142
0.318GlnMet: 0.318 ± 0.42
2.864GlnAsn: 2.864 ± 1.462
2.227GlnPro: 2.227 ± 0.87
1.909GlnGln: 1.909 ± 1.079
1.591GlnArg: 1.591 ± 0.52
0.955GlnSer: 0.955 ± 0.264
2.227GlnThr: 2.227 ± 0.578
1.591GlnVal: 1.591 ± 0.899
0.318GlnTrp: 0.318 ± 0.18
2.227GlnTyr: 2.227 ± 0.796
0.0GlnXaa: 0.0 ± 0.0
Arg
1.909ArgAla: 1.909 ± 1.079
0.955ArgCys: 0.955 ± 0.709
2.545ArgAsp: 2.545 ± 0.211
3.818ArgGlu: 3.818 ± 1.051
0.955ArgPhe: 0.955 ± 0.54
2.227ArgGly: 2.227 ± 1.259
1.273ArgHis: 1.273 ± 0.719
5.409ArgIle: 5.409 ± 1.982
3.5ArgLys: 3.5 ± 0.654
4.773ArgLeu: 4.773 ± 0.097
1.273ArgMet: 1.273 ± 0.447
1.591ArgAsn: 1.591 ± 0.537
2.545ArgPro: 2.545 ± 0.933
2.227ArgGln: 2.227 ± 1.259
1.909ArgArg: 1.909 ± 0.177
4.454ArgSer: 4.454 ± 0.628
3.182ArgThr: 3.182 ± 1.879
2.864ArgVal: 2.864 ± 0.793
0.318ArgTrp: 0.318 ± 0.42
1.909ArgTyr: 1.909 ± 0.629
0.0ArgXaa: 0.0 ± 0.0
Ser
3.818SerAla: 3.818 ± 3.283
2.864SerCys: 2.864 ± 2.338
3.182SerAsp: 3.182 ± 0.489
2.864SerGlu: 2.864 ± 0.526
2.864SerPhe: 2.864 ± 0.799
5.409SerGly: 5.409 ± 0.6
0.955SerHis: 0.955 ± 0.54
6.045SerIle: 6.045 ± 0.672
7.318SerLys: 7.318 ± 0.718
5.091SerLeu: 5.091 ± 0.658
2.864SerMet: 2.864 ± 0.799
4.773SerAsn: 4.773 ± 1.243
0.955SerPro: 0.955 ± 0.264
3.182SerGln: 3.182 ± 0.699
3.5SerArg: 3.5 ± 0.434
4.454SerSer: 4.454 ± 1.614
5.727SerThr: 5.727 ± 0.182
4.773SerVal: 4.773 ± 1.727
0.955SerTrp: 0.955 ± 0.264
3.5SerTyr: 3.5 ± 0.776
0.0SerXaa: 0.0 ± 0.0
Thr
1.909ThrAla: 1.909 ± 0.177
0.636ThrCys: 0.636 ± 0.301
5.409ThrAsp: 5.409 ± 0.853
2.864ThrGlu: 2.864 ± 0.526
2.545ThrPhe: 2.545 ± 0.874
2.864ThrGly: 2.864 ± 1.767
1.273ThrHis: 1.273 ± 0.719
6.045ThrIle: 6.045 ± 0.564
4.454ThrLys: 4.454 ± 0.519
6.363ThrLeu: 6.363 ± 2.554
2.864ThrMet: 2.864 ± 0.618
4.454ThrAsn: 4.454 ± 1.739
1.591ThrPro: 1.591 ± 0.52
0.955ThrGln: 0.955 ± 0.54
3.818ThrArg: 3.818 ± 1.274
5.091ThrSer: 5.091 ± 0.993
3.182ThrThr: 3.182 ± 1.317
2.864ThrVal: 2.864 ± 0.953
0.636ThrTrp: 0.636 ± 0.36
1.909ThrTyr: 1.909 ± 0.529
0.0ThrXaa: 0.0 ± 0.0
Val
4.773ValAla: 4.773 ± 1.156
2.227ValCys: 2.227 ± 0.381
2.864ValAsp: 2.864 ± 0.799
4.454ValGlu: 4.454 ± 0.519
1.273ValPhe: 1.273 ± 1.006
3.182ValGly: 3.182 ± 1.506
1.591ValHis: 1.591 ± 0.471
4.773ValIle: 4.773 ± 0.843
4.136ValLys: 4.136 ± 2.276
4.136ValLeu: 4.136 ± 1.555
3.182ValMet: 3.182 ± 0.192
2.545ValAsn: 2.545 ± 0.792
1.273ValPro: 1.273 ± 0.437
1.591ValGln: 1.591 ± 0.929
2.864ValArg: 2.864 ± 1.142
5.727ValSer: 5.727 ± 0.854
2.864ValThr: 2.864 ± 1.142
3.818ValVal: 3.818 ± 1.057
0.955ValTrp: 0.955 ± 0.54
5.727ValTyr: 5.727 ± 1.486
0.0ValXaa: 0.0 ± 0.0
Trp
2.227TrpAla: 2.227 ± 1.259
0.318TrpCys: 0.318 ± 0.18
0.955TrpAsp: 0.955 ± 0.441
0.636TrpGlu: 0.636 ± 0.84
0.0TrpPhe: 0.0 ± 0.0
0.318TrpGly: 0.318 ± 0.18
0.318TrpHis: 0.318 ± 0.42
1.591TrpIle: 1.591 ± 0.537
0.318TrpLys: 0.318 ± 0.614
0.318TrpLeu: 0.318 ± 0.42
0.318TrpMet: 0.318 ± 0.18
1.591TrpAsn: 1.591 ± 0.537
0.318TrpPro: 0.318 ± 0.18
0.318TrpGln: 0.318 ± 0.18
0.636TrpArg: 0.636 ± 0.503
0.0TrpSer: 0.0 ± 0.0
0.955TrpThr: 0.955 ± 0.607
0.955TrpVal: 0.955 ± 0.54
0.0TrpTrp: 0.0 ± 0.0
0.955TrpTyr: 0.955 ± 0.264
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.591TyrAla: 1.591 ± 0.899
0.636TyrCys: 0.636 ± 0.301
2.545TyrAsp: 2.545 ± 0.967
2.864TyrGlu: 2.864 ± 1.142
0.636TyrPhe: 0.636 ± 0.36
3.818TyrGly: 3.818 ± 1.057
1.273TyrHis: 1.273 ± 0.719
3.5TyrIle: 3.5 ± 1.097
4.136TyrLys: 4.136 ± 0.687
3.182TyrLeu: 3.182 ± 1.317
0.318TyrMet: 0.318 ± 0.42
2.545TyrAsn: 2.545 ± 0.782
2.227TyrPro: 2.227 ± 0.578
1.909TyrGln: 1.909 ± 0.629
2.227TyrArg: 2.227 ± 0.578
2.864TyrSer: 2.864 ± 0.091
2.227TyrThr: 2.227 ± 0.22
2.545TyrVal: 2.545 ± 0.792
0.636TyrTrp: 0.636 ± 0.301
2.545TyrTyr: 2.545 ± 0.674
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3144 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski