Amino acid dipepetide frequency for Diplodia scrobiculata RNA virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.082AlaAla: 15.082 ± 4.186
1.311AlaCys: 1.311 ± 1.865
5.246AlaAsp: 5.246 ± 1.512
4.59AlaGlu: 4.59 ± 0.119
3.279AlaPhe: 3.279 ± 0.464
3.934AlaGly: 3.934 ± 2.095
1.311AlaHis: 1.311 ± 0.698
5.902AlaIle: 5.902 ± 0.579
3.934AlaLys: 3.934 ± 0.813
8.525AlaLeu: 8.525 ± 0.587
2.623AlaMet: 2.623 ± 1.397
1.311AlaAsn: 1.311 ± 0.698
5.902AlaPro: 5.902 ± 1.984
2.623AlaGln: 2.623 ± 1.166
9.18AlaArg: 9.18 ± 2.325
12.459AlaSer: 12.459 ± 1.508
11.148AlaThr: 11.148 ± 0.472
4.59AlaVal: 4.59 ± 1.163
1.311AlaTrp: 1.311 ± 0.698
5.902AlaTyr: 5.902 ± 1.861
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.656CysAsp: 0.656 ± 0.932
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.656CysIle: 0.656 ± 0.349
1.311CysLys: 1.311 ± 0.698
0.656CysLeu: 0.656 ± 0.932
0.656CysMet: 0.656 ± 0.349
0.656CysAsn: 0.656 ± 0.349
1.967CysPro: 1.967 ± 1.047
0.0CysGln: 0.0 ± 0.0
1.311CysArg: 1.311 ± 0.583
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.656CysTrp: 0.656 ± 0.932
1.311CysTyr: 1.311 ± 0.698
0.0CysXaa: 0.0 ± 0.0
Asp
7.213AspAla: 7.213 ± 2.559
0.0AspCys: 0.0 ± 0.0
2.623AspAsp: 2.623 ± 1.397
0.0AspGlu: 0.0 ± 0.0
1.967AspPhe: 1.967 ± 0.234
1.311AspGly: 1.311 ± 0.698
1.967AspHis: 1.967 ± 1.047
2.623AspIle: 2.623 ± 1.166
1.311AspLys: 1.311 ± 0.698
6.557AspLeu: 6.557 ± 0.929
0.0AspMet: 0.0 ± 0.0
1.311AspAsn: 1.311 ± 0.583
3.934AspPro: 3.934 ± 0.468
3.279AspGln: 3.279 ± 2.099
2.623AspArg: 2.623 ± 0.115
3.279AspSer: 3.279 ± 0.464
1.967AspThr: 1.967 ± 1.047
3.279AspVal: 3.279 ± 1.746
2.623AspTrp: 2.623 ± 0.115
1.311AspTyr: 1.311 ± 0.698
0.0AspXaa: 0.0 ± 0.0
Glu
5.246GluAla: 5.246 ± 0.23
1.311GluCys: 1.311 ± 0.698
0.656GluAsp: 0.656 ± 0.349
3.934GluGlu: 3.934 ± 4.312
2.623GluPhe: 2.623 ± 0.115
1.311GluGly: 1.311 ± 0.583
0.0GluHis: 0.0 ± 0.0
1.311GluIle: 1.311 ± 1.865
1.967GluLys: 1.967 ± 1.515
5.246GluLeu: 5.246 ± 2.333
1.311GluMet: 1.311 ± 0.583
1.311GluAsn: 1.311 ± 0.698
4.59GluPro: 4.59 ± 0.119
2.623GluGln: 2.623 ± 2.448
2.623GluArg: 2.623 ± 0.115
2.623GluSer: 2.623 ± 1.166
0.656GluThr: 0.656 ± 0.349
3.934GluVal: 3.934 ± 0.813
0.656GluTrp: 0.656 ± 0.932
1.311GluTyr: 1.311 ± 0.698
0.0GluXaa: 0.0 ± 0.0
Phe
5.902PheAla: 5.902 ± 0.579
0.0PheCys: 0.0 ± 0.0
0.656PheAsp: 0.656 ± 0.349
3.279PheGlu: 3.279 ± 1.746
1.967PhePhe: 1.967 ± 1.047
1.311PheGly: 1.311 ± 0.698
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
0.656PheLys: 0.656 ± 0.349
5.246PheLeu: 5.246 ± 2.793
2.623PheMet: 2.623 ± 1.595
1.311PheAsn: 1.311 ± 0.698
3.279PhePro: 3.279 ± 0.817
0.656PheGln: 0.656 ± 0.932
1.311PheArg: 1.311 ± 0.583
4.59PheSer: 4.59 ± 2.444
1.311PheThr: 1.311 ± 1.865
3.279PheVal: 3.279 ± 0.817
0.656PheTrp: 0.656 ± 0.349
1.311PheTyr: 1.311 ± 0.698
0.0PheXaa: 0.0 ± 0.0
Gly
3.934GlyAla: 3.934 ± 2.095
1.311GlyCys: 1.311 ± 0.698
1.967GlyAsp: 1.967 ± 0.234
4.59GlyGlu: 4.59 ± 0.119
1.967GlyPhe: 1.967 ± 1.047
5.246GlyGly: 5.246 ± 2.793
0.0GlyHis: 0.0 ± 0.0
1.967GlyIle: 1.967 ± 1.515
3.934GlyLys: 3.934 ± 0.468
4.59GlyLeu: 4.59 ± 1.163
1.311GlyMet: 1.311 ± 0.698
0.656GlyAsn: 0.656 ± 0.349
1.311GlyPro: 1.311 ± 0.583
1.967GlyGln: 1.967 ± 0.234
5.246GlyArg: 5.246 ± 1.512
3.934GlySer: 3.934 ± 0.468
3.934GlyThr: 3.934 ± 0.468
1.311GlyVal: 1.311 ± 0.698
0.0GlyTrp: 0.0 ± 0.0
2.623GlyTyr: 2.623 ± 1.397
0.0GlyXaa: 0.0 ± 0.0
His
1.311HisAla: 1.311 ± 0.583
0.0HisCys: 0.0 ± 0.0
1.967HisAsp: 1.967 ± 1.047
0.0HisGlu: 0.0 ± 0.0
0.656HisPhe: 0.656 ± 0.349
1.967HisGly: 1.967 ± 1.047
0.656HisHis: 0.656 ± 0.349
0.0HisIle: 0.0 ± 0.0
1.967HisLys: 1.967 ± 1.515
1.967HisLeu: 1.967 ± 0.234
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.311HisPro: 1.311 ± 0.583
1.967HisGln: 1.967 ± 0.234
2.623HisArg: 2.623 ± 0.115
0.656HisSer: 0.656 ± 0.349
1.311HisThr: 1.311 ± 0.698
1.311HisVal: 1.311 ± 0.698
0.0HisTrp: 0.0 ± 0.0
1.311HisTyr: 1.311 ± 0.698
0.0HisXaa: 0.0 ± 0.0
Ile
3.934IleAla: 3.934 ± 0.468
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
1.311IleGlu: 1.311 ± 0.583
1.311IlePhe: 1.311 ± 0.583
1.311IleGly: 1.311 ± 0.583
0.0IleHis: 0.0 ± 0.0
1.311IleIle: 1.311 ± 0.583
0.656IleLys: 0.656 ± 0.932
4.59IleLeu: 4.59 ± 0.119
2.623IleMet: 2.623 ± 0.115
0.656IleAsn: 0.656 ± 0.349
1.967IlePro: 1.967 ± 1.047
0.0IleGln: 0.0 ± 0.0
3.934IleArg: 3.934 ± 0.468
2.623IleSer: 2.623 ± 0.115
4.59IleThr: 4.59 ± 0.119
0.656IleVal: 0.656 ± 0.932
1.311IleTrp: 1.311 ± 0.698
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.59LysAla: 4.59 ± 0.119
0.0LysCys: 0.0 ± 0.0
1.311LysAsp: 1.311 ± 1.865
1.967LysGlu: 1.967 ± 2.797
1.311LysPhe: 1.311 ± 0.698
3.279LysGly: 3.279 ± 2.099
0.656LysHis: 0.656 ± 0.932
2.623LysIle: 2.623 ± 0.115
1.311LysLys: 1.311 ± 0.583
4.59LysLeu: 4.59 ± 1.4
1.311LysMet: 1.311 ± 0.258
1.967LysAsn: 1.967 ± 0.234
2.623LysPro: 2.623 ± 2.448
0.0LysGln: 0.0 ± 0.0
3.279LysArg: 3.279 ± 1.746
0.0LysSer: 0.0 ± 0.0
2.623LysThr: 2.623 ± 2.448
1.311LysVal: 1.311 ± 0.698
1.311LysTrp: 1.311 ± 1.865
1.311LysTyr: 1.311 ± 0.583
0.0LysXaa: 0.0 ± 0.0
Leu
15.738LeuAla: 15.738 ± 4.535
1.311LeuCys: 1.311 ± 0.698
5.246LeuAsp: 5.246 ± 1.512
3.279LeuGlu: 3.279 ± 0.817
4.59LeuPhe: 4.59 ± 2.444
4.59LeuGly: 4.59 ± 1.163
1.967LeuHis: 1.967 ± 0.234
3.934LeuIle: 3.934 ± 1.75
3.279LeuLys: 3.279 ± 2.099
17.049LeuLeu: 17.049 ± 2.455
1.311LeuMet: 1.311 ± 0.698
1.967LeuAsn: 1.967 ± 0.234
10.492LeuPro: 10.492 ± 5.586
7.869LeuGln: 7.869 ± 0.345
9.836LeuArg: 9.836 ± 5.014
7.213LeuSer: 7.213 ± 2.567
3.934LeuThr: 3.934 ± 2.095
4.59LeuVal: 4.59 ± 1.163
1.311LeuTrp: 1.311 ± 0.583
1.967LeuTyr: 1.967 ± 1.515
0.0LeuXaa: 0.0 ± 0.0
Met
1.967MetAla: 1.967 ± 2.797
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.311MetGlu: 1.311 ± 1.865
1.967MetPhe: 1.967 ± 0.234
1.967MetGly: 1.967 ± 1.515
1.311MetHis: 1.311 ± 0.698
0.656MetIle: 0.656 ± 0.932
0.0MetLys: 0.0 ± 0.0
3.279MetLeu: 3.279 ± 1.746
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.967MetPro: 1.967 ± 1.047
1.311MetGln: 1.311 ± 0.698
1.967MetArg: 1.967 ± 0.234
1.967MetSer: 1.967 ± 1.047
0.0MetThr: 0.0 ± 0.0
0.656MetVal: 0.656 ± 0.349
0.656MetTrp: 0.656 ± 0.349
0.656MetTyr: 0.656 ± 0.349
0.0MetXaa: 0.0 ± 0.0
Asn
1.311AsnAla: 1.311 ± 0.698
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.967AsnGlu: 1.967 ± 0.234
0.656AsnPhe: 0.656 ± 0.349
1.311AsnGly: 1.311 ± 0.698
1.311AsnHis: 1.311 ± 0.698
0.656AsnIle: 0.656 ± 0.349
1.311AsnLys: 1.311 ± 0.698
1.967AsnLeu: 1.967 ± 1.515
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
1.311AsnPro: 1.311 ± 1.865
1.311AsnGln: 1.311 ± 1.865
0.656AsnArg: 0.656 ± 0.349
2.623AsnSer: 2.623 ± 0.115
2.623AsnThr: 2.623 ± 1.397
1.311AsnVal: 1.311 ± 0.583
0.656AsnTrp: 0.656 ± 0.349
0.656AsnTyr: 0.656 ± 0.932
0.0AsnXaa: 0.0 ± 0.0
Pro
5.246ProAla: 5.246 ± 0.23
0.656ProCys: 0.656 ± 0.349
4.59ProAsp: 4.59 ± 1.163
2.623ProGlu: 2.623 ± 0.115
1.311ProPhe: 1.311 ± 0.583
3.934ProGly: 3.934 ± 0.468
3.934ProHis: 3.934 ± 0.468
1.311ProIle: 1.311 ± 0.698
1.311ProLys: 1.311 ± 0.583
3.934ProLeu: 3.934 ± 0.468
1.311ProMet: 1.311 ± 0.583
2.623ProAsn: 2.623 ± 0.115
9.18ProPro: 9.18 ± 3.607
3.279ProGln: 3.279 ± 3.38
9.18ProArg: 9.18 ± 1.044
9.18ProSer: 9.18 ± 1.519
5.246ProThr: 5.246 ± 1.051
3.934ProVal: 3.934 ± 2.095
0.656ProTrp: 0.656 ± 0.932
1.311ProTyr: 1.311 ± 0.698
0.0ProXaa: 0.0 ± 0.0
Gln
3.279GlnAla: 3.279 ± 2.099
0.0GlnCys: 0.0 ± 0.0
1.967GlnAsp: 1.967 ± 0.234
3.279GlnGlu: 3.279 ± 0.464
1.311GlnPhe: 1.311 ± 0.698
3.279GlnGly: 3.279 ± 1.746
1.311GlnHis: 1.311 ± 0.583
1.311GlnIle: 1.311 ± 0.583
1.967GlnLys: 1.967 ± 2.797
5.246GlnLeu: 5.246 ± 1.512
2.623GlnMet: 2.623 ± 2.448
0.0GlnAsn: 0.0 ± 0.0
2.623GlnPro: 2.623 ± 1.166
0.656GlnGln: 0.656 ± 0.932
5.246GlnArg: 5.246 ± 1.051
3.934GlnSer: 3.934 ± 0.468
3.934GlnThr: 3.934 ± 0.468
0.0GlnVal: 0.0 ± 0.0
1.311GlnTrp: 1.311 ± 0.583
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
9.836ArgAla: 9.836 ± 2.674
0.656ArgCys: 0.656 ± 0.932
4.59ArgAsp: 4.59 ± 1.163
3.934ArgGlu: 3.934 ± 0.468
2.623ArgPhe: 2.623 ± 1.397
1.967ArgGly: 1.967 ± 0.234
1.967ArgHis: 1.967 ± 0.234
2.623ArgIle: 2.623 ± 1.397
2.623ArgLys: 2.623 ± 2.448
9.18ArgLeu: 9.18 ± 0.238
1.967ArgMet: 1.967 ± 1.515
2.623ArgAsn: 2.623 ± 1.166
5.902ArgPro: 5.902 ± 0.702
4.59ArgGln: 4.59 ± 1.163
9.18ArgArg: 9.18 ± 3.607
9.18ArgSer: 9.18 ± 1.519
2.623ArgThr: 2.623 ± 0.115
5.246ArgVal: 5.246 ± 1.051
1.311ArgTrp: 1.311 ± 1.865
2.623ArgTyr: 2.623 ± 1.397
0.0ArgXaa: 0.0 ± 0.0
Ser
8.525SerAla: 8.525 ± 1.868
0.0SerCys: 0.0 ± 0.0
4.59SerAsp: 4.59 ± 1.163
3.279SerGlu: 3.279 ± 0.464
4.59SerPhe: 4.59 ± 1.163
5.902SerGly: 5.902 ± 0.579
1.311SerHis: 1.311 ± 0.698
3.934SerIle: 3.934 ± 0.813
2.623SerLys: 2.623 ± 1.166
9.836SerLeu: 9.836 ± 1.393
0.656SerMet: 0.656 ± 0.349
1.311SerAsn: 1.311 ± 1.865
5.902SerPro: 5.902 ± 1.984
5.246SerGln: 5.246 ± 1.512
5.902SerArg: 5.902 ± 3.265
7.869SerSer: 7.869 ± 3.499
4.59SerThr: 4.59 ± 1.4
5.246SerVal: 5.246 ± 1.051
1.311SerTrp: 1.311 ± 0.698
0.656SerTyr: 0.656 ± 0.349
0.0SerXaa: 0.0 ± 0.0
Thr
5.246ThrAla: 5.246 ± 1.051
1.311ThrCys: 1.311 ± 0.698
3.934ThrAsp: 3.934 ± 1.75
1.311ThrGlu: 1.311 ± 1.865
1.967ThrPhe: 1.967 ± 1.047
3.934ThrGly: 3.934 ± 0.813
0.656ThrHis: 0.656 ± 0.349
0.0ThrIle: 0.0 ± 0.0
3.279ThrLys: 3.279 ± 2.099
6.557ThrLeu: 6.557 ± 3.491
0.0ThrMet: 0.0 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
5.246ThrPro: 5.246 ± 0.23
3.279ThrGln: 3.279 ± 0.817
3.934ThrArg: 3.934 ± 0.468
3.934ThrSer: 3.934 ± 1.75
4.59ThrThr: 4.59 ± 0.119
7.869ThrVal: 7.869 ± 0.936
1.967ThrTrp: 1.967 ± 1.047
0.656ThrTyr: 0.656 ± 0.349
0.0ThrXaa: 0.0 ± 0.0
Val
6.557ValAla: 6.557 ± 2.21
1.311ValCys: 1.311 ± 0.583
4.59ValAsp: 4.59 ± 1.163
4.59ValGlu: 4.59 ± 1.4
3.934ValPhe: 3.934 ± 0.468
1.311ValGly: 1.311 ± 0.583
0.656ValHis: 0.656 ± 0.349
0.656ValIle: 0.656 ± 0.349
2.623ValLys: 2.623 ± 0.115
7.213ValLeu: 7.213 ± 0.004
0.0ValMet: 0.0 ± 0.0
1.967ValAsn: 1.967 ± 0.234
1.967ValPro: 1.967 ± 1.047
1.311ValGln: 1.311 ± 0.698
4.59ValArg: 4.59 ± 1.163
4.59ValSer: 4.59 ± 0.119
1.967ValThr: 1.967 ± 1.047
2.623ValVal: 2.623 ± 1.166
0.656ValTrp: 0.656 ± 0.349
1.967ValTyr: 1.967 ± 0.234
0.0ValXaa: 0.0 ± 0.0
Trp
0.656TrpAla: 0.656 ± 0.349
0.0TrpCys: 0.0 ± 0.0
2.623TrpAsp: 2.623 ± 1.397
0.0TrpGlu: 0.0 ± 0.0
0.656TrpPhe: 0.656 ± 0.932
1.967TrpGly: 1.967 ± 1.047
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.656TrpLys: 0.656 ± 0.932
3.279TrpLeu: 3.279 ± 0.817
0.0TrpMet: 0.0 ± 0.0
1.311TrpAsn: 1.311 ± 0.583
1.311TrpPro: 1.311 ± 1.865
0.0TrpGln: 0.0 ± 0.0
1.311TrpArg: 1.311 ± 0.583
0.0TrpSer: 0.0 ± 0.0
1.967TrpThr: 1.967 ± 1.515
1.311TrpVal: 1.311 ± 0.698
0.656TrpTrp: 0.656 ± 0.932
1.311TrpTyr: 1.311 ± 0.698
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.59TyrAla: 4.59 ± 2.444
0.656TyrCys: 0.656 ± 0.349
1.967TyrAsp: 1.967 ± 0.234
0.0TyrGlu: 0.0 ± 0.0
1.311TyrPhe: 1.311 ± 0.698
1.967TyrGly: 1.967 ± 1.047
1.967TyrHis: 1.967 ± 0.234
1.311TyrIle: 1.311 ± 0.698
0.656TyrLys: 0.656 ± 0.932
1.967TyrLeu: 1.967 ± 1.047
0.656TyrMet: 0.656 ± 0.932
0.656TyrAsn: 0.656 ± 0.349
1.967TyrPro: 1.967 ± 1.047
1.311TyrGln: 1.311 ± 0.698
1.311TyrArg: 1.311 ± 0.698
2.623TyrSer: 2.623 ± 0.115
0.656TyrThr: 0.656 ± 0.349
2.623TyrVal: 2.623 ± 0.115
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1526 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski