Amino acid dipepetide frequency for Kibdelosporangium phytohabitans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.432AlaAla: 18.432 ± 0.113	1.035AlaCys: 1.035 ± 0.022	8.267AlaAsp: 8.267 ± 0.061	7.974AlaGlu: 7.974 ± 0.066	3.443AlaPhe: 3.443 ± 0.03	12.308AlaGly: 12.308 ± 0.062	2.557AlaHis: 2.557 ± 0.031	4.512AlaIle: 4.512 ± 0.044	3.259AlaLys: 3.259 ± 0.042	12.969AlaLeu: 12.969 ± 0.081	2.656AlaMet: 2.656 ± 0.024	2.593AlaAsn: 2.593 ± 0.032	5.533AlaPro: 5.533 ± 0.051	3.86AlaGln: 3.86 ± 0.038	8.97AlaArg: 8.97 ± 0.062	5.814AlaSer: 5.814 ± 0.045	7.325AlaThr: 7.325 ± 0.052	11.779AlaVal: 11.779 ± 0.074	1.838AlaTrp: 1.838 ± 0.024	2.373AlaTyr: 2.373 ± 0.027	0.0AlaXaa: 0.0 ± 0.0
Cys	1.03CysAla: 1.03 ± 0.019	0.099CysCys: 0.099 ± 0.006	0.474CysAsp: 0.474 ± 0.013	0.405CysGlu: 0.405 ± 0.012	0.217CysPhe: 0.217 ± 0.009	0.914CysGly: 0.914 ± 0.018	0.204CysHis: 0.204 ± 0.008	0.145CysIle: 0.145 ± 0.007	0.127CysLys: 0.127 ± 0.007	0.74CysLeu: 0.74 ± 0.018	0.128CysMet: 0.128 ± 0.007	0.142CysAsn: 0.142 ± 0.007	0.481CysPro: 0.481 ± 0.015	0.225CysGln: 0.225 ± 0.008	0.606CysArg: 0.606 ± 0.014	0.461CysSer: 0.461 ± 0.012	0.504CysThr: 0.504 ± 0.013	0.691CysVal: 0.691 ± 0.015	0.135CysTrp: 0.135 ± 0.007	0.191CysTyr: 0.191 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	7.069AspAla: 7.069 ± 0.056	0.418AspCys: 0.418 ± 0.011	3.656AspAsp: 3.656 ± 0.038	4.013AspGlu: 4.013 ± 0.035	1.682AspPhe: 1.682 ± 0.023	6.058AspGly: 6.058 ± 0.053	1.434AspHis: 1.434 ± 0.021	2.228AspIle: 2.228 ± 0.027	1.467AspLys: 1.467 ± 0.026	6.474AspLeu: 6.474 ± 0.05	0.964AspMet: 0.964 ± 0.017	1.354AspAsn: 1.354 ± 0.022	4.306AspPro: 4.306 ± 0.034	1.927AspGln: 1.927 ± 0.027	4.843AspArg: 4.843 ± 0.037	2.806AspSer: 2.806 ± 0.031	3.236AspThr: 3.236 ± 0.03	5.438AspVal: 5.438 ± 0.044	1.032AspTrp: 1.032 ± 0.015	1.28AspTyr: 1.28 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	5.923GluAla: 5.923 ± 0.05	0.37GluCys: 0.37 ± 0.013	2.467GluAsp: 2.467 ± 0.028	2.356GluGlu: 2.356 ± 0.034	1.752GluPhe: 1.752 ± 0.02	3.062GluGly: 3.062 ± 0.034	1.612GluHis: 1.612 ± 0.021	2.426GluIle: 2.426 ± 0.028	1.217GluLys: 1.217 ± 0.022	6.882GluLeu: 6.882 ± 0.053	0.922GluMet: 0.922 ± 0.017	1.088GluAsn: 1.088 ± 0.018	3.159GluPro: 3.159 ± 0.036	2.415GluGln: 2.415 ± 0.027	4.628GluArg: 4.628 ± 0.042	2.513GluSer: 2.513 ± 0.028	2.699GluThr: 2.699 ± 0.034	4.564GluVal: 4.564 ± 0.043	0.854GluTrp: 0.854 ± 0.017	1.118GluTyr: 1.118 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.872PheAla: 3.872 ± 0.034	0.258PheCys: 0.258 ± 0.009	2.312PheAsp: 2.312 ± 0.028	1.458PheGlu: 1.458 ± 0.023	0.918PhePhe: 0.918 ± 0.021	3.27PheGly: 3.27 ± 0.037	0.668PheHis: 0.668 ± 0.014	0.783PheIle: 0.783 ± 0.017	0.503PheLys: 0.503 ± 0.013	2.511PheLeu: 2.511 ± 0.034	0.425PheMet: 0.425 ± 0.013	0.617PheAsn: 0.617 ± 0.015	1.429PhePro: 1.429 ± 0.02	0.756PheGln: 0.756 ± 0.016	1.853PheArg: 1.853 ± 0.024	1.545PheSer: 1.545 ± 0.026	2.171PheThr: 2.171 ± 0.028	2.588PheVal: 2.588 ± 0.031	0.423PheTrp: 0.423 ± 0.012	0.622PheTyr: 0.622 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	9.418GlyAla: 9.418 ± 0.061	0.823GlyCys: 0.823 ± 0.017	5.135GlyAsp: 5.135 ± 0.043	4.65GlyGlu: 4.65 ± 0.043	2.97GlyPhe: 2.97 ± 0.031	7.808GlyGly: 7.808 ± 0.074	2.215GlyHis: 2.215 ± 0.03	3.76GlyIle: 3.76 ± 0.037	2.848GlyLys: 2.848 ± 0.039	8.901GlyLeu: 8.901 ± 0.062	2.121GlyMet: 2.121 ± 0.028	2.215GlyAsn: 2.215 ± 0.037	4.481GlyPro: 4.481 ± 0.04	2.998GlyGln: 2.998 ± 0.032	6.597GlyArg: 6.597 ± 0.055	5.041GlySer: 5.041 ± 0.042	5.88GlyThr: 5.88 ± 0.043	7.842GlyVal: 7.842 ± 0.055	1.73GlyTrp: 1.73 ± 0.022	2.315GlyTyr: 2.315 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	2.563HisAla: 2.563 ± 0.029	0.216HisCys: 0.216 ± 0.008	1.427HisAsp: 1.427 ± 0.022	1.207HisGlu: 1.207 ± 0.02	0.613HisPhe: 0.613 ± 0.013	2.279HisGly: 2.279 ± 0.031	0.675HisHis: 0.675 ± 0.019	0.71HisIle: 0.71 ± 0.018	0.442HisLys: 0.442 ± 0.01	2.254HisLeu: 2.254 ± 0.025	0.372HisMet: 0.372 ± 0.013	0.492HisAsn: 0.492 ± 0.013	1.628HisPro: 1.628 ± 0.026	0.723HisGln: 0.723 ± 0.016	1.89HisArg: 1.89 ± 0.028	1.104HisSer: 1.104 ± 0.019	1.277HisThr: 1.277 ± 0.022	1.897HisVal: 1.897 ± 0.023	0.358HisTrp: 0.358 ± 0.01	0.498HisTyr: 0.498 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	5.485IleAla: 5.485 ± 0.045	0.299IleCys: 0.299 ± 0.01	2.709IleAsp: 2.709 ± 0.028	2.266IleGlu: 2.266 ± 0.028	0.781IlePhe: 0.781 ± 0.02	4.093IleGly: 4.093 ± 0.041	0.653IleHis: 0.653 ± 0.015	1.025IleIle: 1.025 ± 0.02	0.843IleLys: 0.843 ± 0.016	2.611IleLeu: 2.611 ± 0.035	0.504IleMet: 0.504 ± 0.014	0.869IleAsn: 0.869 ± 0.016	2.083IlePro: 2.083 ± 0.027	0.877IleGln: 0.877 ± 0.018	2.61IleArg: 2.61 ± 0.029	2.021IleSer: 2.021 ± 0.026	2.751IleThr: 2.751 ± 0.033	3.303IleVal: 3.303 ± 0.04	0.46IleTrp: 0.46 ± 0.013	0.615IleTyr: 0.615 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	3.004LysAla: 3.004 ± 0.033	0.141LysCys: 0.141 ± 0.007	1.314LysAsp: 1.314 ± 0.023	1.042LysGlu: 1.042 ± 0.021	0.638LysPhe: 0.638 ± 0.013	1.569LysGly: 1.569 ± 0.027	0.558LysHis: 0.558 ± 0.013	0.991LysIle: 0.991 ± 0.019	0.624LysLys: 0.624 ± 0.018	2.495LysLeu: 2.495 ± 0.03	0.418LysMet: 0.418 ± 0.011	0.477LysAsn: 0.477 ± 0.014	1.724LysPro: 1.724 ± 0.027	0.903LysGln: 0.903 ± 0.018	1.657LysArg: 1.657 ± 0.025	1.23LysSer: 1.23 ± 0.021	1.38LysThr: 1.38 ± 0.027	2.113LysVal: 2.113 ± 0.028	0.353LysTrp: 0.353 ± 0.011	0.505LysTyr: 0.505 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	14.886LeuAla: 14.886 ± 0.09	0.789LeuCys: 0.789 ± 0.018	6.754LeuAsp: 6.754 ± 0.056	4.196LeuGlu: 4.196 ± 0.043	2.688LeuPhe: 2.688 ± 0.033	8.932LeuGly: 8.932 ± 0.066	2.176LeuHis: 2.176 ± 0.03	3.652LeuIle: 3.652 ± 0.042	1.894LeuLys: 1.894 ± 0.028	10.611LeuLeu: 10.611 ± 0.076	1.58LeuMet: 1.58 ± 0.025	1.957LeuAsn: 1.957 ± 0.026	6.113LeuPro: 6.113 ± 0.066	2.081LeuGln: 2.081 ± 0.026	8.658LeuArg: 8.658 ± 0.07	5.694LeuSer: 5.694 ± 0.047	6.847LeuThr: 6.847 ± 0.051	9.531LeuVal: 9.531 ± 0.06	1.304LeuTrp: 1.304 ± 0.027	1.675LeuTyr: 1.675 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.368MetAla: 2.368 ± 0.025	0.137MetCys: 0.137 ± 0.007	0.94MetAsp: 0.94 ± 0.017	0.643MetGlu: 0.643 ± 0.014	0.555MetPhe: 0.555 ± 0.014	1.263MetGly: 1.263 ± 0.022	0.393MetHis: 0.393 ± 0.01	0.865MetIle: 0.865 ± 0.018	0.405MetLys: 0.405 ± 0.011	1.923MetLeu: 1.923 ± 0.025	0.313MetMet: 0.313 ± 0.011	0.443MetAsn: 0.443 ± 0.01	1.212MetPro: 1.212 ± 0.02	0.462MetGln: 0.462 ± 0.011	1.66MetArg: 1.66 ± 0.025	1.331MetSer: 1.331 ± 0.021	1.628MetThr: 1.628 ± 0.022	1.542MetVal: 1.542 ± 0.024	0.242MetTrp: 0.242 ± 0.009	0.313MetTyr: 0.313 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.674AsnAla: 2.674 ± 0.031	0.19AsnCys: 0.19 ± 0.008	1.215AsnAsp: 1.215 ± 0.025	1.003AsnGlu: 1.003 ± 0.018	0.565AsnPhe: 0.565 ± 0.014	2.331AsnGly: 2.331 ± 0.034	0.473AsnHis: 0.473 ± 0.012	0.723AsnIle: 0.723 ± 0.016	0.509AsnLys: 0.509 ± 0.014	2.012AsnLeu: 2.012 ± 0.026	0.316AsnMet: 0.316 ± 0.01	0.582AsnAsn: 0.582 ± 0.017	1.678AsnPro: 1.678 ± 0.025	0.73AsnGln: 0.73 ± 0.013	1.549AsnArg: 1.549 ± 0.022	1.121AsnSer: 1.121 ± 0.021	1.403AsnThr: 1.403 ± 0.023	1.699AsnVal: 1.699 ± 0.025	0.341AsnTrp: 0.341 ± 0.012	0.486AsnTyr: 0.486 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	7.431ProAla: 7.431 ± 0.053	0.359ProCys: 0.359 ± 0.013	4.543ProAsp: 4.543 ± 0.041	3.511ProGlu: 3.511 ± 0.042	1.57ProPhe: 1.57 ± 0.023	6.105ProGly: 6.105 ± 0.05	1.21ProHis: 1.21 ± 0.022	1.808ProIle: 1.808 ± 0.022	1.298ProLys: 1.298 ± 0.021	4.874ProLeu: 4.874 ± 0.042	1.115ProMet: 1.115 ± 0.017	1.24ProAsn: 1.24 ± 0.019	3.497ProPro: 3.497 ± 0.062	1.781ProGln: 1.781 ± 0.027	3.643ProArg: 3.643 ± 0.033	3.177ProSer: 3.177 ± 0.03	3.061ProThr: 3.061 ± 0.031	5.502ProVal: 5.502 ± 0.052	0.877ProTrp: 0.877 ± 0.017	1.164ProTyr: 1.164 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	4.02GlnAla: 4.02 ± 0.034	0.213GlnCys: 0.213 ± 0.009	1.492GlnAsp: 1.492 ± 0.021	1.272GlnGlu: 1.272 ± 0.019	0.897GlnPhe: 0.897 ± 0.019	2.104GlnGly: 2.104 ± 0.024	0.701GlnHis: 0.701 ± 0.015	1.22GlnIle: 1.22 ± 0.02	0.573GlnLys: 0.573 ± 0.016	3.546GlnLeu: 3.546 ± 0.035	0.53GlnMet: 0.53 ± 0.015	0.624GlnAsn: 0.624 ± 0.015	2.104GlnPro: 2.104 ± 0.03	1.484GlnGln: 1.484 ± 0.027	2.815GlnArg: 2.815 ± 0.029	1.488GlnSer: 1.488 ± 0.022	1.481GlnThr: 1.481 ± 0.022	2.848GlnVal: 2.848 ± 0.03	0.55GlnTrp: 0.55 ± 0.013	0.642GlnTyr: 0.642 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	8.868ArgAla: 8.868 ± 0.07	0.61ArgCys: 0.61 ± 0.016	4.515ArgAsp: 4.515 ± 0.041	4.109ArgGlu: 4.109 ± 0.039	2.473ArgPhe: 2.473 ± 0.024	5.405ArgGly: 5.405 ± 0.049	1.926ArgHis: 1.926 ± 0.027	3.319ArgIle: 3.319 ± 0.033	1.93ArgLys: 1.93 ± 0.028	8.376ArgLeu: 8.376 ± 0.066	1.877ArgMet: 1.877 ± 0.024	1.637ArgAsn: 1.637 ± 0.017	4.298ArgPro: 4.298 ± 0.043	2.64ArgGln: 2.64 ± 0.031	6.718ArgArg: 6.718 ± 0.053	3.96ArgSer: 3.96 ± 0.039	4.95ArgThr: 4.95 ± 0.037	6.081ArgVal: 6.081 ± 0.043	1.39ArgTrp: 1.39 ± 0.02	1.86ArgTyr: 1.86 ± 0.026	0.0ArgXaa: 0.0 ± 0.0
Ser	6.753SerAla: 6.753 ± 0.048	0.444SerCys: 0.444 ± 0.013	2.818SerAsp: 2.818 ± 0.033	2.336SerGlu: 2.336 ± 0.026	1.61SerPhe: 1.61 ± 0.021	5.963SerGly: 5.963 ± 0.048	0.986SerHis: 0.986 ± 0.019	1.843SerIle: 1.843 ± 0.028	1.16SerLys: 1.16 ± 0.019	4.996SerLeu: 4.996 ± 0.047	1.236SerMet: 1.236 ± 0.019	1.049SerAsn: 1.049 ± 0.021	3.15SerPro: 3.15 ± 0.032	1.47SerGln: 1.47 ± 0.024	3.806SerArg: 3.806 ± 0.032	3.05SerSer: 3.05 ± 0.039	3.483SerThr: 3.483 ± 0.038	4.595SerVal: 4.595 ± 0.036	0.968SerTrp: 0.968 ± 0.017	1.233SerTyr: 1.233 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	8.288ThrAla: 8.288 ± 0.053	0.469ThrCys: 0.469 ± 0.015	3.558ThrAsp: 3.558 ± 0.033	3.185ThrGlu: 3.185 ± 0.029	1.733ThrPhe: 1.733 ± 0.027	6.58ThrGly: 6.58 ± 0.06	1.213ThrHis: 1.213 ± 0.02	2.237ThrIle: 2.237 ± 0.028	1.426ThrLys: 1.426 ± 0.027	5.555ThrLeu: 5.555 ± 0.037	1.13ThrMet: 1.13 ± 0.019	1.3ThrAsn: 1.3 ± 0.02	3.849ThrPro: 3.849 ± 0.036	1.59ThrGln: 1.59 ± 0.023	4.1ThrArg: 4.1 ± 0.034	3.573ThrSer: 3.573 ± 0.038	4.153ThrThr: 4.153 ± 0.039	6.271ThrVal: 6.271 ± 0.049	1.015ThrTrp: 1.015 ± 0.018	1.383ThrTyr: 1.383 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	11.408ValAla: 11.408 ± 0.064	0.708ValCys: 0.708 ± 0.016	5.873ValAsp: 5.873 ± 0.049	4.642ValGlu: 4.642 ± 0.042	2.65ValPhe: 2.65 ± 0.031	6.704ValGly: 6.704 ± 0.053	2.071ValHis: 2.071 ± 0.024	3.455ValIle: 3.455 ± 0.028	1.894ValLys: 1.894 ± 0.026	10.117ValLeu: 10.117 ± 0.07	1.451ValMet: 1.451 ± 0.02	2.025ValAsn: 2.025 ± 0.025	5.019ValPro: 5.019 ± 0.047	2.275ValGln: 2.275 ± 0.03	7.038ValArg: 7.038 ± 0.058	4.933ValSer: 4.933 ± 0.041	6.076ValThr: 6.076 ± 0.051	8.932ValVal: 8.932 ± 0.072	1.135ValTrp: 1.135 ± 0.02	1.577ValTyr: 1.577 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	1.619TrpAla: 1.619 ± 0.026	0.16TrpCys: 0.16 ± 0.007	0.846TrpAsp: 0.846 ± 0.019	0.675TrpGlu: 0.675 ± 0.016	0.541TrpPhe: 0.541 ± 0.012	1.016TrpGly: 1.016 ± 0.018	0.444TrpHis: 0.444 ± 0.013	0.618TrpIle: 0.618 ± 0.014	0.316TrpLys: 0.316 ± 0.01	1.956TrpLeu: 1.956 ± 0.025	0.313TrpMet: 0.313 ± 0.01	0.424TrpAsn: 0.424 ± 0.012	0.877TrpPro: 0.877 ± 0.017	0.681TrpGln: 0.681 ± 0.016	1.413TrpArg: 1.413 ± 0.023	0.965TrpSer: 0.965 ± 0.018	1.05TrpThr: 1.05 ± 0.021	1.1TrpVal: 1.1 ± 0.019	0.378TrpTrp: 0.378 ± 0.011	0.352TrpTyr: 0.352 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.385TyrAla: 2.385 ± 0.027	0.18TyrCys: 0.18 ± 0.007	1.371TyrAsp: 1.371 ± 0.029	1.082TyrGlu: 1.082 ± 0.018	0.687TyrPhe: 0.687 ± 0.014	1.984TyrGly: 1.984 ± 0.026	0.455TyrHis: 0.455 ± 0.011	0.539TyrIle: 0.539 ± 0.013	0.404TyrLys: 0.404 ± 0.011	2.217TyrLeu: 2.217 ± 0.025	0.268TyrMet: 0.268 ± 0.009	0.471TyrAsn: 0.471 ± 0.013	1.143TyrPro: 1.143 ± 0.019	0.729TyrGln: 0.729 ± 0.015	1.887TyrArg: 1.887 ± 0.024	1.121TyrSer: 1.121 ± 0.019	1.253TyrThr: 1.253 ± 0.023	1.664TyrVal: 1.664 ± 0.025	0.361TyrTrp: 0.361 ± 0.011	0.463TyrTyr: 0.463 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10118 proteins (3331434 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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