Amino acid dipepetide frequency for Rubripirellula obstinata

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.518AlaAla: 10.518 ± 0.101	1.225AlaCys: 1.225 ± 0.037	6.36AlaAsp: 6.36 ± 0.074	5.752AlaGlu: 5.752 ± 0.073	3.299AlaPhe: 3.299 ± 0.041	7.816AlaGly: 7.816 ± 0.101	1.297AlaHis: 1.297 ± 0.032	6.217AlaIle: 6.217 ± 0.06	4.363AlaLys: 4.363 ± 0.081	7.018AlaLeu: 7.018 ± 0.074	2.961AlaMet: 2.961 ± 0.054	3.37AlaAsn: 3.37 ± 0.069	3.429AlaPro: 3.429 ± 0.059	2.663AlaGln: 2.663 ± 0.042	4.677AlaArg: 4.677 ± 0.07	6.951AlaSer: 6.951 ± 0.069	5.938AlaThr: 5.938 ± 0.102	6.672AlaVal: 6.672 ± 0.073	1.238AlaTrp: 1.238 ± 0.029	1.926AlaTyr: 1.926 ± 0.035	0.0AlaXaa: 0.0 ± 0.0
Cys	0.66CysAla: 0.66 ± 0.024	0.233CysCys: 0.233 ± 0.013	0.818CysAsp: 0.818 ± 0.026	0.744CysGlu: 0.744 ± 0.026	0.485CysPhe: 0.485 ± 0.018	1.203CysGly: 1.203 ± 0.045	0.4CysHis: 0.4 ± 0.018	0.547CysIle: 0.547 ± 0.02	0.385CysLys: 0.385 ± 0.017	1.145CysLeu: 1.145 ± 0.031	0.227CysMet: 0.227 ± 0.012	0.378CysAsn: 0.378 ± 0.016	0.677CysPro: 0.677 ± 0.025	0.403CysGln: 0.403 ± 0.015	0.881CysArg: 0.881 ± 0.024	0.763CysSer: 0.763 ± 0.022	0.537CysThr: 0.537 ± 0.021	0.847CysVal: 0.847 ± 0.026	0.174CysTrp: 0.174 ± 0.011	0.291CysTyr: 0.291 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	6.659AspAla: 6.659 ± 0.084	0.736AspCys: 0.736 ± 0.024	4.809AspAsp: 4.809 ± 0.101	4.331AspGlu: 4.331 ± 0.061	2.648AspPhe: 2.648 ± 0.045	5.856AspGly: 5.856 ± 0.14	1.49AspHis: 1.49 ± 0.031	2.616AspIle: 2.616 ± 0.043	1.783AspLys: 1.783 ± 0.044	6.096AspLeu: 6.096 ± 0.071	1.032AspMet: 1.032 ± 0.025	1.894AspAsn: 1.894 ± 0.061	3.608AspPro: 3.608 ± 0.05	3.301AspGln: 3.301 ± 0.046	4.528AspArg: 4.528 ± 0.056	4.622AspSer: 4.622 ± 0.065	2.908AspThr: 2.908 ± 0.1	4.535AspVal: 4.535 ± 0.078	1.128AspTrp: 1.128 ± 0.026	1.637AspTyr: 1.637 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	5.197GluAla: 5.197 ± 0.076	0.499GluCys: 0.499 ± 0.018	3.007GluAsp: 3.007 ± 0.047	3.157GluGlu: 3.157 ± 0.073	2.202GluPhe: 2.202 ± 0.035	3.206GluGly: 3.206 ± 0.044	1.143GluHis: 1.143 ± 0.028	3.612GluIle: 3.612 ± 0.045	2.6GluLys: 2.6 ± 0.058	6.298GluLeu: 6.298 ± 0.073	1.585GluMet: 1.585 ± 0.039	2.135GluAsn: 2.135 ± 0.04	2.566GluPro: 2.566 ± 0.044	2.546GluGln: 2.546 ± 0.041	3.252GluArg: 3.252 ± 0.06	4.882GluSer: 4.882 ± 0.067	3.979GluThr: 3.979 ± 0.046	4.219GluVal: 4.219 ± 0.054	0.521GluTrp: 0.521 ± 0.016	1.163GluTyr: 1.163 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.954PheAla: 3.954 ± 0.048	0.497PheCys: 0.497 ± 0.016	3.224PheAsp: 3.224 ± 0.063	2.149PheGlu: 2.149 ± 0.039	1.571PhePhe: 1.571 ± 0.032	3.43PheGly: 3.43 ± 0.047	0.746PheHis: 0.746 ± 0.02	1.488PheIle: 1.488 ± 0.028	1.086PheLys: 1.086 ± 0.027	3.213PheLeu: 3.213 ± 0.046	0.641PheMet: 0.641 ± 0.018	1.299PheAsn: 1.299 ± 0.034	1.583PhePro: 1.583 ± 0.031	1.374PheGln: 1.374 ± 0.026	2.343PheArg: 2.343 ± 0.037	2.675PheSer: 2.675 ± 0.043	2.069PheThr: 2.069 ± 0.054	2.857PheVal: 2.857 ± 0.04	0.536PheTrp: 0.536 ± 0.017	0.905PheTyr: 0.905 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	5.398GlyAla: 5.398 ± 0.076	1.065GlyCys: 1.065 ± 0.043	5.321GlyAsp: 5.321 ± 0.095	4.398GlyGlu: 4.398 ± 0.057	3.169GlyPhe: 3.169 ± 0.047	6.718GlyGly: 6.718 ± 0.141	1.66GlyHis: 1.66 ± 0.036	4.317GlyIle: 4.317 ± 0.064	3.513GlyLys: 3.513 ± 0.068	6.828GlyLeu: 6.828 ± 0.064	1.981GlyMet: 1.981 ± 0.041	3.022GlyAsn: 3.022 ± 0.094	2.893GlyPro: 2.893 ± 0.043	3.032GlyGln: 3.032 ± 0.051	4.681GlyArg: 4.681 ± 0.073	5.567GlySer: 5.567 ± 0.101	4.559GlyThr: 4.559 ± 0.152	5.381GlyVal: 5.381 ± 0.067	1.207GlyTrp: 1.207 ± 0.029	1.995GlyTyr: 1.995 ± 0.033	0.0GlyXaa: 0.0 ± 0.0
His	1.784HisAla: 1.784 ± 0.036	0.395HisCys: 0.395 ± 0.017	1.293HisAsp: 1.293 ± 0.032	1.044HisGlu: 1.044 ± 0.022	0.938HisPhe: 0.938 ± 0.025	1.612HisGly: 1.612 ± 0.033	0.652HisHis: 0.652 ± 0.022	0.799HisIle: 0.799 ± 0.022	0.474HisLys: 0.474 ± 0.017	2.116HisLeu: 2.116 ± 0.04	0.31HisMet: 0.31 ± 0.013	0.58HisAsn: 0.58 ± 0.018	1.252HisPro: 1.252 ± 0.029	1.067HisGln: 1.067 ± 0.027	1.751HisArg: 1.751 ± 0.038	1.336HisSer: 1.336 ± 0.031	0.873HisThr: 0.873 ± 0.023	1.468HisVal: 1.468 ± 0.029	0.414HisTrp: 0.414 ± 0.014	0.547HisTyr: 0.547 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.561IleAla: 6.561 ± 0.076	0.624IleCys: 0.624 ± 0.019	4.882IleAsp: 4.882 ± 0.063	4.2IleGlu: 4.2 ± 0.048	1.522IlePhe: 1.522 ± 0.032	4.58IleGly: 4.58 ± 0.053	1.085IleHis: 1.085 ± 0.025	2.084IleIle: 2.084 ± 0.037	1.733IleLys: 1.733 ± 0.041	3.929IleLeu: 3.929 ± 0.048	0.748IleMet: 0.748 ± 0.02	1.927IleAsn: 1.927 ± 0.049	2.537IlePro: 2.537 ± 0.045	1.995IleGln: 1.995 ± 0.034	3.583IleArg: 3.583 ± 0.05	3.585IleSer: 3.585 ± 0.057	3.025IleThr: 3.025 ± 0.071	4.081IleVal: 4.081 ± 0.049	0.503IleTrp: 0.503 ± 0.016	1.134IleTyr: 1.134 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	3.189LysAla: 3.189 ± 0.063	0.357LysCys: 0.357 ± 0.017	1.855LysAsp: 1.855 ± 0.04	1.912LysGlu: 1.912 ± 0.047	1.328LysPhe: 1.328 ± 0.03	1.939LysGly: 1.939 ± 0.051	0.891LysHis: 0.891 ± 0.029	2.093LysIle: 2.093 ± 0.045	2.05LysLys: 2.05 ± 0.054	3.919LysLeu: 3.919 ± 0.066	1.002LysMet: 1.002 ± 0.025	1.304LysAsn: 1.304 ± 0.036	2.249LysPro: 2.249 ± 0.048	1.81LysGln: 1.81 ± 0.043	2.69LysArg: 2.69 ± 0.057	2.839LysSer: 2.839 ± 0.062	2.576LysThr: 2.576 ± 0.051	2.517LysVal: 2.517 ± 0.049	0.508LysTrp: 0.508 ± 0.019	0.849LysTyr: 0.849 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	9.613LeuAla: 9.613 ± 0.095	1.158LeuCys: 1.158 ± 0.029	5.919LeuAsp: 5.919 ± 0.075	4.905LeuGlu: 4.905 ± 0.057	3.275LeuPhe: 3.275 ± 0.046	6.839LeuGly: 6.839 ± 0.078	1.943LeuHis: 1.943 ± 0.037	5.12LeuIle: 5.12 ± 0.058	3.459LeuLys: 3.459 ± 0.064	8.664LeuLeu: 8.664 ± 0.099	2.122LeuMet: 2.122 ± 0.042	2.952LeuAsn: 2.952 ± 0.05	5.038LeuPro: 5.038 ± 0.062	3.506LeuGln: 3.506 ± 0.053	6.184LeuArg: 6.184 ± 0.066	6.712LeuSer: 6.712 ± 0.069	5.377LeuThr: 5.377 ± 0.096	6.706LeuVal: 6.706 ± 0.074	1.075LeuTrp: 1.075 ± 0.029	1.817LeuTyr: 1.817 ± 0.034	0.0LeuXaa: 0.0 ± 0.0
Met	2.138MetAla: 2.138 ± 0.043	0.193MetCys: 0.193 ± 0.01	1.185MetAsp: 1.185 ± 0.025	1.071MetGlu: 1.071 ± 0.028	0.79MetPhe: 0.79 ± 0.024	1.467MetGly: 1.467 ± 0.036	0.516MetHis: 0.516 ± 0.02	1.465MetIle: 1.465 ± 0.033	1.052MetLys: 1.052 ± 0.028	2.526MetLeu: 2.526 ± 0.043	0.71MetMet: 0.71 ± 0.021	0.95MetAsn: 0.95 ± 0.024	1.492MetPro: 1.492 ± 0.035	1.067MetGln: 1.067 ± 0.026	1.467MetArg: 1.467 ± 0.031	1.654MetSer: 1.654 ± 0.03	1.643MetThr: 1.643 ± 0.033	1.664MetVal: 1.664 ± 0.037	0.231MetTrp: 0.231 ± 0.011	0.353MetTyr: 0.353 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.25AsnAla: 3.25 ± 0.061	0.371AsnCys: 0.371 ± 0.013	2.4AsnAsp: 2.4 ± 0.084	2.004AsnGlu: 2.004 ± 0.034	1.291AsnPhe: 1.291 ± 0.031	2.683AsnGly: 2.683 ± 0.071	0.841AsnHis: 0.841 ± 0.024	1.369AsnIle: 1.369 ± 0.035	1.033AsnLys: 1.033 ± 0.028	3.143AsnLeu: 3.143 ± 0.047	0.591AsnMet: 0.591 ± 0.017	1.22AsnAsn: 1.22 ± 0.048	2.094AsnPro: 2.094 ± 0.04	1.79AsnGln: 1.79 ± 0.031	2.551AsnArg: 2.551 ± 0.042	2.342AsnSer: 2.342 ± 0.049	1.765AsnThr: 1.765 ± 0.061	2.49AsnVal: 2.49 ± 0.059	0.472AsnTrp: 0.472 ± 0.014	0.843AsnTyr: 0.843 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	4.771ProAla: 4.771 ± 0.067	0.437ProCys: 0.437 ± 0.02	3.34ProAsp: 3.34 ± 0.044	3.316ProGlu: 3.316 ± 0.043	1.609ProPhe: 1.609 ± 0.036	3.668ProGly: 3.668 ± 0.056	0.893ProHis: 0.893 ± 0.027	2.817ProIle: 2.817 ± 0.047	1.97ProLys: 1.97 ± 0.043	3.948ProLeu: 3.948 ± 0.056	1.31ProMet: 1.31 ± 0.032	1.851ProAsn: 1.851 ± 0.038	2.476ProPro: 2.476 ± 0.049	1.68ProGln: 1.68 ± 0.031	2.492ProArg: 2.492 ± 0.05	3.774ProSer: 3.774 ± 0.052	3.365ProThr: 3.365 ± 0.044	3.646ProVal: 3.646 ± 0.052	0.658ProTrp: 0.658 ± 0.021	1.002ProTyr: 1.002 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.667GlnAla: 3.667 ± 0.052	0.478GlnCys: 0.478 ± 0.017	1.828GlnAsp: 1.828 ± 0.03	1.69GlnGlu: 1.69 ± 0.035	1.607GlnPhe: 1.607 ± 0.03	2.156GlnGly: 2.156 ± 0.041	0.919GlnHis: 0.919 ± 0.022	2.364GlnIle: 2.364 ± 0.035	1.484GlnLys: 1.484 ± 0.034	4.014GlnLeu: 4.014 ± 0.055	0.999GlnMet: 0.999 ± 0.026	1.422GlnAsn: 1.422 ± 0.028	2.161GlnPro: 2.161 ± 0.041	2.073GlnGln: 2.073 ± 0.049	2.895GlnArg: 2.895 ± 0.048	3.34GlnSer: 3.34 ± 0.044	2.657GlnThr: 2.657 ± 0.043	2.761GlnVal: 2.761 ± 0.046	0.729GlnTrp: 0.729 ± 0.022	0.931GlnTyr: 0.931 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	4.231ArgAla: 4.231 ± 0.059	0.795ArgCys: 0.795 ± 0.024	3.864ArgAsp: 3.864 ± 0.047	3.515ArgGlu: 3.515 ± 0.064	2.877ArgPhe: 2.877 ± 0.04	4.215ArgGly: 4.215 ± 0.06	1.479ArgHis: 1.479 ± 0.038	3.802ArgIle: 3.802 ± 0.047	2.515ArgLys: 2.515 ± 0.049	6.729ArgLeu: 6.729 ± 0.088	1.84ArgMet: 1.84 ± 0.036	2.12ArgAsn: 2.12 ± 0.037	2.874ArgPro: 2.874 ± 0.052	2.716ArgGln: 2.716 ± 0.047	4.985ArgArg: 4.985 ± 0.089	4.739ArgSer: 4.739 ± 0.062	3.289ArgThr: 3.289 ± 0.056	4.383ArgVal: 4.383 ± 0.056	1.192ArgTrp: 1.192 ± 0.03	1.768ArgTyr: 1.768 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.168SerAla: 6.168 ± 0.07	0.737SerCys: 0.737 ± 0.027	4.948SerAsp: 4.948 ± 0.065	4.257SerGlu: 4.257 ± 0.06	2.707SerPhe: 2.707 ± 0.049	6.339SerGly: 6.339 ± 0.094	1.345SerHis: 1.345 ± 0.029	4.154SerIle: 4.154 ± 0.044	2.688SerLys: 2.688 ± 0.048	6.995SerLeu: 6.995 ± 0.068	1.812SerMet: 1.812 ± 0.034	2.487SerAsn: 2.487 ± 0.046	3.711SerPro: 3.711 ± 0.05	2.71SerGln: 2.71 ± 0.043	4.428SerArg: 4.428 ± 0.068	5.282SerSer: 5.282 ± 0.078	3.94SerThr: 3.94 ± 0.084	5.445SerVal: 5.445 ± 0.064	0.847SerTrp: 0.847 ± 0.027	1.429SerTyr: 1.429 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	5.506ThrAla: 5.506 ± 0.094	0.571ThrCys: 0.571 ± 0.019	3.878ThrAsp: 3.878 ± 0.121	3.283ThrGlu: 3.283 ± 0.048	2.228ThrPhe: 2.228 ± 0.072	4.847ThrGly: 4.847 ± 0.121	1.135ThrHis: 1.135 ± 0.03	3.731ThrIle: 3.731 ± 0.091	2.087ThrLys: 2.087 ± 0.047	5.742ThrLeu: 5.742 ± 0.091	1.249ThrMet: 1.249 ± 0.034	2.061ThrAsn: 2.061 ± 0.068	3.239ThrPro: 3.239 ± 0.055	2.044ThrGln: 2.044 ± 0.035	3.182ThrArg: 3.182 ± 0.062	3.799ThrSer: 3.799 ± 0.067	3.617ThrThr: 3.617 ± 0.084	4.546ThrVal: 4.546 ± 0.13	0.75ThrTrp: 0.75 ± 0.021	1.273ThrTyr: 1.273 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	7.487ValAla: 7.487 ± 0.075	0.951ValCys: 0.951 ± 0.03	5.011ValAsp: 5.011 ± 0.085	4.1ValGlu: 4.1 ± 0.057	2.556ValPhe: 2.556 ± 0.037	5.558ValGly: 5.558 ± 0.073	1.379ValHis: 1.379 ± 0.026	4.004ValIle: 4.004 ± 0.055	2.335ValLys: 2.335 ± 0.048	6.336ValLeu: 6.336 ± 0.069	1.722ValMet: 1.722 ± 0.032	2.33ValAsn: 2.33 ± 0.054	3.431ValPro: 3.431 ± 0.056	2.559ValGln: 2.559 ± 0.038	4.451ValArg: 4.451 ± 0.055	5.188ValSer: 5.188 ± 0.059	4.648ValThr: 4.648 ± 0.133	5.65ValVal: 5.65 ± 0.063	0.907ValTrp: 0.907 ± 0.026	1.63ValTyr: 1.63 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	0.958TrpAla: 0.958 ± 0.027	0.192TrpCys: 0.192 ± 0.011	0.772TrpAsp: 0.772 ± 0.023	0.604TrpGlu: 0.604 ± 0.018	0.541TrpPhe: 0.541 ± 0.015	0.822TrpGly: 0.822 ± 0.022	0.334TrpHis: 0.334 ± 0.014	0.932TrpIle: 0.932 ± 0.023	0.623TrpLys: 0.623 ± 0.021	1.54TrpLeu: 1.54 ± 0.032	0.454TrpMet: 0.454 ± 0.017	0.583TrpAsn: 0.583 ± 0.02	0.567TrpPro: 0.567 ± 0.02	0.681TrpGln: 0.681 ± 0.02	0.866TrpArg: 0.866 ± 0.023	0.928TrpSer: 0.928 ± 0.021	0.858TrpThr: 0.858 ± 0.026	0.869TrpVal: 0.869 ± 0.025	0.253TrpTrp: 0.253 ± 0.012	0.33TrpTyr: 0.33 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.979TyrAla: 1.979 ± 0.03	0.283TyrCys: 0.283 ± 0.014	1.506TyrAsp: 1.506 ± 0.033	1.338TyrGlu: 1.338 ± 0.029	0.998TyrPhe: 0.998 ± 0.024	1.754TyrGly: 1.754 ± 0.032	0.557TyrHis: 0.557 ± 0.02	0.786TyrIle: 0.786 ± 0.021	0.646TyrLys: 0.646 ± 0.024	2.182TyrLeu: 2.182 ± 0.037	0.338TyrMet: 0.338 ± 0.013	0.654TyrAsn: 0.654 ± 0.021	1.146TyrPro: 1.146 ± 0.027	1.159TyrGln: 1.159 ± 0.026	2.043TyrArg: 2.043 ± 0.036	1.451TyrSer: 1.451 ± 0.032	1.146TyrThr: 1.146 ± 0.049	1.494TyrVal: 1.494 ± 0.029	0.364TyrTrp: 0.364 ± 0.015	0.634TyrTyr: 0.634 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5669 proteins (1934098 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---