Amino acid dipepetide frequency for Phialocephala scopiformis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.984AlaAla: 7.984 ± 0.047	1.136AlaCys: 1.136 ± 0.013	3.747AlaAsp: 3.747 ± 0.022	4.766AlaGlu: 4.766 ± 0.031	3.237AlaPhe: 3.237 ± 0.021	5.519AlaGly: 5.519 ± 0.031	1.61AlaHis: 1.61 ± 0.015	4.492AlaIle: 4.492 ± 0.029	4.015AlaLys: 4.015 ± 0.024	7.496AlaLeu: 7.496 ± 0.034	1.914AlaMet: 1.914 ± 0.016	2.939AlaAsn: 2.939 ± 0.019	4.235AlaPro: 4.235 ± 0.029	3.06AlaGln: 3.06 ± 0.024	4.288AlaArg: 4.288 ± 0.029	6.93AlaSer: 6.93 ± 0.037	5.159AlaThr: 5.159 ± 0.032	5.067AlaVal: 5.067 ± 0.028	1.189AlaTrp: 1.189 ± 0.013	2.208AlaTyr: 2.208 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.968CysAla: 0.968 ± 0.01	0.305CysCys: 0.305 ± 0.008	0.69CysAsp: 0.69 ± 0.008	0.642CysGlu: 0.642 ± 0.01	0.626CysPhe: 0.626 ± 0.01	1.053CysGly: 1.053 ± 0.014	0.357CysHis: 0.357 ± 0.007	0.807CysIle: 0.807 ± 0.01	0.608CysLys: 0.608 ± 0.009	1.378CysLeu: 1.378 ± 0.015	0.302CysMet: 0.302 ± 0.006	0.483CysAsn: 0.483 ± 0.008	0.727CysPro: 0.727 ± 0.011	0.508CysGln: 0.508 ± 0.008	0.756CysArg: 0.756 ± 0.011	1.071CysSer: 1.071 ± 0.014	0.801CysThr: 0.801 ± 0.011	0.83CysVal: 0.83 ± 0.011	0.25CysTrp: 0.25 ± 0.006	0.402CysTyr: 0.402 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.201AspAla: 4.201 ± 0.026	0.68AspCys: 0.68 ± 0.01	3.747AspAsp: 3.747 ± 0.034	4.255AspGlu: 4.255 ± 0.03	2.354AspPhe: 2.354 ± 0.017	3.898AspGly: 3.898 ± 0.025	1.188AspHis: 1.188 ± 0.014	3.167AspIle: 3.167 ± 0.022	2.295AspLys: 2.295 ± 0.022	5.043AspLeu: 5.043 ± 0.025	1.26AspMet: 1.26 ± 0.013	1.879AspAsn: 1.879 ± 0.018	3.169AspPro: 3.169 ± 0.025	1.781AspGln: 1.781 ± 0.017	2.685AspArg: 2.685 ± 0.022	3.955AspSer: 3.955 ± 0.023	2.902AspThr: 2.902 ± 0.02	3.556AspVal: 3.556 ± 0.023	0.951AspTrp: 0.951 ± 0.012	1.602AspTyr: 1.602 ± 0.013	0.0AspXaa: 0.0 ± 0.0
Glu	5.04GluAla: 5.04 ± 0.027	0.663GluCys: 0.663 ± 0.01	4.154GluAsp: 4.154 ± 0.026	5.504GluGlu: 5.504 ± 0.042	2.02GluPhe: 2.02 ± 0.016	3.828GluGly: 3.828 ± 0.028	1.359GluHis: 1.359 ± 0.014	3.324GluIle: 3.324 ± 0.024	3.947GluLys: 3.947 ± 0.028	5.134GluLeu: 5.134 ± 0.029	1.558GluMet: 1.558 ± 0.016	2.419GluAsn: 2.419 ± 0.02	2.547GluPro: 2.547 ± 0.022	2.29GluGln: 2.29 ± 0.021	3.796GluArg: 3.796 ± 0.028	4.28GluSer: 4.28 ± 0.026	3.412GluThr: 3.412 ± 0.021	3.778GluVal: 3.778 ± 0.022	0.957GluTrp: 0.957 ± 0.012	1.753GluTyr: 1.753 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.156PheAla: 3.156 ± 0.026	0.645PheCys: 0.645 ± 0.01	2.35PheAsp: 2.35 ± 0.015	2.374PheGlu: 2.374 ± 0.017	1.787PhePhe: 1.787 ± 0.017	3.08PheGly: 3.08 ± 0.024	0.935PheHis: 0.935 ± 0.011	1.964PheIle: 1.964 ± 0.018	1.683PheLys: 1.683 ± 0.015	3.712PheLeu: 3.712 ± 0.026	0.882PheMet: 0.882 ± 0.011	1.552PheAsn: 1.552 ± 0.014	2.082PhePro: 2.082 ± 0.017	1.489PheGln: 1.489 ± 0.013	1.971PheArg: 1.971 ± 0.015	3.227PheSer: 3.227 ± 0.024	2.342PheThr: 2.342 ± 0.017	2.542PheVal: 2.542 ± 0.018	0.745PheTrp: 0.745 ± 0.01	1.166PheTyr: 1.166 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	4.998GlyAla: 4.998 ± 0.036	0.964GlyCys: 0.964 ± 0.012	3.421GlyAsp: 3.421 ± 0.023	3.702GlyGlu: 3.702 ± 0.025	3.002GlyPhe: 3.002 ± 0.021	5.729GlyGly: 5.729 ± 0.045	1.595GlyHis: 1.595 ± 0.015	3.808GlyIle: 3.808 ± 0.023	3.647GlyLys: 3.647 ± 0.025	6.093GlyLeu: 6.093 ± 0.033	1.724GlyMet: 1.724 ± 0.014	2.696GlyAsn: 2.696 ± 0.023	3.165GlyPro: 3.165 ± 0.025	2.341GlyGln: 2.341 ± 0.017	3.773GlyArg: 3.773 ± 0.027	5.642GlySer: 5.642 ± 0.034	4.226GlyThr: 4.226 ± 0.03	4.41GlyVal: 4.41 ± 0.027	1.27GlyTrp: 1.27 ± 0.013	2.227GlyTyr: 2.227 ± 0.019	0.0GlyXaa: 0.0 ± 0.0
His	1.673HisAla: 1.673 ± 0.016	0.369HisCys: 0.369 ± 0.008	1.232HisAsp: 1.232 ± 0.013	1.335HisGlu: 1.335 ± 0.014	0.964HisPhe: 0.964 ± 0.011	1.606HisGly: 1.606 ± 0.014	0.781HisHis: 0.781 ± 0.011	1.24HisIle: 1.24 ± 0.012	0.938HisLys: 0.938 ± 0.011	2.241HisLeu: 2.241 ± 0.02	0.497HisMet: 0.497 ± 0.008	0.864HisAsn: 0.864 ± 0.011	1.517HisPro: 1.517 ± 0.014	0.939HisGln: 0.939 ± 0.01	1.375HisArg: 1.375 ± 0.015	1.781HisSer: 1.781 ± 0.015	1.287HisThr: 1.287 ± 0.012	1.369HisVal: 1.369 ± 0.014	0.357HisTrp: 0.357 ± 0.007	0.691HisTyr: 0.691 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	4.399IleAla: 4.399 ± 0.027	0.86IleCys: 0.86 ± 0.009	2.98IleAsp: 2.98 ± 0.02	3.152IleGlu: 3.152 ± 0.024	2.291IlePhe: 2.291 ± 0.021	3.509IleGly: 3.509 ± 0.027	1.258IleHis: 1.258 ± 0.012	2.903IleIle: 2.903 ± 0.023	2.378IleLys: 2.378 ± 0.018	5.056IleLeu: 5.056 ± 0.032	1.142IleMet: 1.142 ± 0.012	1.979IleAsn: 1.979 ± 0.015	3.244IlePro: 3.244 ± 0.022	2.007IleGln: 2.007 ± 0.016	2.755IleArg: 2.755 ± 0.02	4.327IleSer: 4.327 ± 0.027	3.2IleThr: 3.2 ± 0.024	3.418IleVal: 3.418 ± 0.025	0.859IleTrp: 0.859 ± 0.01	1.585IleTyr: 1.585 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.239LysAla: 4.239 ± 0.028	0.569LysCys: 0.569 ± 0.008	2.924LysAsp: 2.924 ± 0.024	3.59LysGlu: 3.59 ± 0.027	1.629LysPhe: 1.629 ± 0.015	3.139LysGly: 3.139 ± 0.024	1.191LysHis: 1.191 ± 0.012	2.591LysIle: 2.591 ± 0.022	3.515LysLys: 3.515 ± 0.035	4.22LysLeu: 4.22 ± 0.025	1.136LysMet: 1.136 ± 0.012	1.863LysAsn: 1.863 ± 0.016	2.56LysPro: 2.56 ± 0.022	1.795LysGln: 1.795 ± 0.014	3.298LysArg: 3.298 ± 0.024	3.779LysSer: 3.779 ± 0.026	2.995LysThr: 2.995 ± 0.021	3.008LysVal: 3.008 ± 0.021	0.753LysTrp: 0.753 ± 0.01	1.481LysTyr: 1.481 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	7.556LeuAla: 7.556 ± 0.036	1.3LeuCys: 1.3 ± 0.015	5.04LeuAsp: 5.04 ± 0.029	5.611LeuGlu: 5.611 ± 0.032	3.531LeuPhe: 3.531 ± 0.026	6.038LeuGly: 6.038 ± 0.032	2.228LeuHis: 2.228 ± 0.016	4.271LeuIle: 4.271 ± 0.026	4.463LeuLys: 4.463 ± 0.026	8.535LeuLeu: 8.535 ± 0.044	1.883LeuMet: 1.883 ± 0.016	3.333LeuAsn: 3.333 ± 0.021	5.492LeuPro: 5.492 ± 0.027	3.777LeuGln: 3.777 ± 0.024	5.301LeuArg: 5.301 ± 0.034	7.534LeuSer: 7.534 ± 0.038	4.956LeuThr: 4.956 ± 0.029	5.415LeuVal: 5.415 ± 0.028	1.319LeuTrp: 1.319 ± 0.014	2.458LeuTyr: 2.458 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	2.17MetAla: 2.17 ± 0.018	0.271MetCys: 0.271 ± 0.007	1.265MetAsp: 1.265 ± 0.014	1.339MetGlu: 1.339 ± 0.012	0.842MetPhe: 0.842 ± 0.01	1.527MetGly: 1.527 ± 0.015	0.493MetHis: 0.493 ± 0.009	1.164MetIle: 1.164 ± 0.012	1.182MetLys: 1.182 ± 0.013	1.944MetLeu: 1.944 ± 0.016	0.635MetMet: 0.635 ± 0.01	0.9MetAsn: 0.9 ± 0.011	1.249MetPro: 1.249 ± 0.012	0.871MetGln: 0.871 ± 0.013	1.25MetArg: 1.25 ± 0.012	1.968MetSer: 1.968 ± 0.017	1.349MetThr: 1.349 ± 0.012	1.353MetVal: 1.353 ± 0.014	0.302MetTrp: 0.302 ± 0.006	0.575MetTyr: 0.575 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.151AsnAla: 3.151 ± 0.023	0.517AsnCys: 0.517 ± 0.009	1.99AsnAsp: 1.99 ± 0.015	2.102AsnGlu: 2.102 ± 0.017	1.561AsnPhe: 1.561 ± 0.013	3.206AsnGly: 3.206 ± 0.024	0.889AsnHis: 0.889 ± 0.009	2.267AsnIle: 2.267 ± 0.017	1.563AsnLys: 1.563 ± 0.013	3.453AsnLeu: 3.453 ± 0.022	0.888AsnMet: 0.888 ± 0.011	1.599AsnAsn: 1.599 ± 0.017	2.428AsnPro: 2.428 ± 0.021	1.355AsnGln: 1.355 ± 0.013	1.83AsnArg: 1.83 ± 0.015	3.075AsnSer: 3.075 ± 0.025	2.462AsnThr: 2.462 ± 0.02	2.438AsnVal: 2.438 ± 0.02	0.629AsnTrp: 0.629 ± 0.009	1.16AsnTyr: 1.16 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.56ProAla: 4.56 ± 0.028	0.551ProCys: 0.551 ± 0.008	2.905ProAsp: 2.905 ± 0.021	3.635ProGlu: 3.635 ± 0.022	2.079ProPhe: 2.079 ± 0.016	3.571ProGly: 3.571 ± 0.027	1.202ProHis: 1.202 ± 0.012	2.766ProIle: 2.766 ± 0.017	2.713ProLys: 2.713 ± 0.022	4.688ProLeu: 4.688 ± 0.027	1.06ProMet: 1.06 ± 0.013	2.3ProAsn: 2.3 ± 0.018	4.512ProPro: 4.512 ± 0.052	2.26ProGln: 2.26 ± 0.021	3.131ProArg: 3.131 ± 0.025	5.634ProSer: 5.634 ± 0.039	3.959ProThr: 3.959 ± 0.024	3.256ProVal: 3.256 ± 0.022	0.758ProTrp: 0.758 ± 0.011	1.588ProTyr: 1.588 ± 0.014	0.0ProXaa: 0.0 ± 0.0
Gln	3.16GlnAla: 3.16 ± 0.027	0.487GlnCys: 0.487 ± 0.009	2.036GlnAsp: 2.036 ± 0.018	2.289GlnGlu: 2.289 ± 0.02	1.334GlnPhe: 1.334 ± 0.013	2.235GlnGly: 2.235 ± 0.017	0.984GlnHis: 0.984 ± 0.011	2.027GlnIle: 2.027 ± 0.016	2.002GlnLys: 2.002 ± 0.019	3.257GlnLeu: 3.257 ± 0.019	0.904GlnMet: 0.904 ± 0.011	1.638GlnAsn: 1.638 ± 0.017	2.185GlnPro: 2.185 ± 0.02	2.069GlnGln: 2.069 ± 0.029	2.356GlnArg: 2.356 ± 0.019	3.036GlnSer: 3.036 ± 0.025	2.323GlnThr: 2.323 ± 0.019	2.161GlnVal: 2.161 ± 0.015	0.598GlnTrp: 0.598 ± 0.01	1.219GlnTyr: 1.219 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.117ArgAla: 4.117 ± 0.023	0.741ArgCys: 0.741 ± 0.01	3.088ArgAsp: 3.088 ± 0.028	3.606ArgGlu: 3.606 ± 0.025	2.041ArgPhe: 2.041 ± 0.017	3.481ArgGly: 3.481 ± 0.028	1.396ArgHis: 1.396 ± 0.014	2.907ArgIle: 2.907 ± 0.021	3.397ArgLys: 3.397 ± 0.024	5.039ArgLeu: 5.039 ± 0.033	1.283ArgMet: 1.283 ± 0.013	2.22ArgAsn: 2.22 ± 0.018	3.02ArgPro: 3.02 ± 0.024	2.314ArgGln: 2.314 ± 0.02	4.432ArgArg: 4.432 ± 0.036	4.39ArgSer: 4.39 ± 0.031	3.138ArgThr: 3.138 ± 0.022	3.113ArgVal: 3.113 ± 0.023	0.949ArgTrp: 0.949 ± 0.011	1.632ArgTyr: 1.632 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	6.261SerAla: 6.261 ± 0.035	1.039SerCys: 1.039 ± 0.013	4.024SerAsp: 4.024 ± 0.027	4.209SerGlu: 4.209 ± 0.029	3.301SerPhe: 3.301 ± 0.02	5.488SerGly: 5.488 ± 0.033	1.841SerHis: 1.841 ± 0.016	4.52SerIle: 4.52 ± 0.027	4.009SerLys: 4.009 ± 0.026	7.324SerLeu: 7.324 ± 0.035	1.86SerMet: 1.86 ± 0.016	3.317SerAsn: 3.317 ± 0.022	5.223SerPro: 5.223 ± 0.039	3.249SerGln: 3.249 ± 0.024	4.665SerArg: 4.665 ± 0.031	9.315SerSer: 9.315 ± 0.096	6.171SerThr: 6.171 ± 0.04	4.525SerVal: 4.525 ± 0.026	1.225SerTrp: 1.225 ± 0.013	2.251SerTyr: 2.251 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.028ThrAla: 5.028 ± 0.027	0.879ThrCys: 0.879 ± 0.012	2.77ThrAsp: 2.77 ± 0.02	3.083ThrGlu: 3.083 ± 0.024	2.629ThrPhe: 2.629 ± 0.02	4.164ThrGly: 4.164 ± 0.026	1.253ThrHis: 1.253 ± 0.013	3.578ThrIle: 3.578 ± 0.025	2.817ThrLys: 2.817 ± 0.018	5.534ThrLeu: 5.534 ± 0.029	1.302ThrMet: 1.302 ± 0.012	2.377ThrAsn: 2.377 ± 0.018	4.139ThrPro: 4.139 ± 0.031	2.141ThrGln: 2.141 ± 0.016	2.97ThrArg: 2.97 ± 0.02	5.914ThrSer: 5.914 ± 0.036	4.675ThrThr: 4.675 ± 0.036	3.702ThrVal: 3.702 ± 0.023	0.961ThrTrp: 0.961 ± 0.013	1.818ThrTyr: 1.818 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	4.994ValAla: 4.994 ± 0.028	0.867ValCys: 0.867 ± 0.013	3.576ValAsp: 3.576 ± 0.021	4.004ValGlu: 4.004 ± 0.027	2.522ValPhe: 2.522 ± 0.019	4.127ValGly: 4.127 ± 0.025	1.34ValHis: 1.34 ± 0.013	3.08ValIle: 3.08 ± 0.022	3.012ValLys: 3.012 ± 0.02	5.683ValLeu: 5.683 ± 0.03	1.362ValMet: 1.362 ± 0.013	2.247ValAsn: 2.247 ± 0.018	3.459ValPro: 3.459 ± 0.021	2.297ValGln: 2.297 ± 0.017	3.125ValArg: 3.125 ± 0.021	4.595ValSer: 4.595 ± 0.029	3.53ValThr: 3.53 ± 0.025	4.382ValVal: 4.382 ± 0.031	0.975ValTrp: 0.975 ± 0.011	1.752ValTyr: 1.752 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	1.164TrpAla: 1.164 ± 0.012	0.226TrpCys: 0.226 ± 0.005	0.941TrpAsp: 0.941 ± 0.011	0.927TrpGlu: 0.927 ± 0.011	0.621TrpPhe: 0.621 ± 0.011	1.048TrpGly: 1.048 ± 0.012	0.37TrpHis: 0.37 ± 0.006	0.888TrpIle: 0.888 ± 0.012	0.91TrpLys: 0.91 ± 0.011	1.424TrpLeu: 1.424 ± 0.015	0.428TrpMet: 0.428 ± 0.008	0.713TrpAsn: 0.713 ± 0.01	0.643TrpPro: 0.643 ± 0.009	0.594TrpGln: 0.594 ± 0.008	0.98TrpArg: 0.98 ± 0.011	1.154TrpSer: 1.154 ± 0.012	1.056TrpThr: 1.056 ± 0.013	0.958TrpVal: 0.958 ± 0.013	0.307TrpTrp: 0.307 ± 0.007	0.496TrpTyr: 0.496 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.171TyrAla: 2.171 ± 0.019	0.497TyrCys: 0.497 ± 0.008	1.689TyrAsp: 1.689 ± 0.015	1.64TyrGlu: 1.64 ± 0.015	1.311TyrPhe: 1.311 ± 0.014	2.186TyrGly: 2.186 ± 0.021	0.783TyrHis: 0.783 ± 0.011	1.538TyrIle: 1.538 ± 0.016	1.181TyrLys: 1.181 ± 0.013	2.787TyrLeu: 2.787 ± 0.018	0.628TyrMet: 0.628 ± 0.009	1.247TyrAsn: 1.247 ± 0.015	1.53TyrPro: 1.53 ± 0.016	1.167TyrGln: 1.167 ± 0.013	1.567TyrArg: 1.567 ± 0.016	2.209TyrSer: 2.209 ± 0.017	1.79TyrThr: 1.79 ± 0.015	1.648TyrVal: 1.648 ± 0.016	0.493TyrTrp: 0.493 ± 0.01	0.993TyrTyr: 0.993 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 18561 proteins (7937098 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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