Amino acid dipepetide frequency for Hubei picorna-like virus 53

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.567AlaAla: 3.567 ± 0.0
0.238AlaCys: 0.238 ± 0.0
2.854AlaAsp: 2.854 ± 0.0
2.854AlaGlu: 2.854 ± 0.0
3.567AlaPhe: 3.567 ± 0.0
4.281AlaGly: 4.281 ± 0.0
1.902AlaHis: 1.902 ± 0.0
3.567AlaIle: 3.567 ± 0.0
3.092AlaLys: 3.092 ± 0.0
5.232AlaLeu: 5.232 ± 0.0
2.616AlaMet: 2.616 ± 0.0
3.567AlaAsn: 3.567 ± 0.0
1.665AlaPro: 1.665 ± 0.0
1.665AlaGln: 1.665 ± 0.0
2.854AlaArg: 2.854 ± 0.0
5.232AlaSer: 5.232 ± 0.0
4.756AlaThr: 4.756 ± 0.0
4.518AlaVal: 4.518 ± 0.0
0.238AlaTrp: 0.238 ± 0.0
1.902AlaTyr: 1.902 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.713CysAla: 0.713 ± 0.0
0.238CysCys: 0.238 ± 0.0
0.713CysAsp: 0.713 ± 0.0
1.427CysGlu: 1.427 ± 0.0
0.713CysPhe: 0.713 ± 0.0
0.713CysGly: 0.713 ± 0.0
0.238CysHis: 0.238 ± 0.0
0.476CysIle: 0.476 ± 0.0
0.476CysLys: 0.476 ± 0.0
1.189CysLeu: 1.189 ± 0.0
0.476CysMet: 0.476 ± 0.0
0.951CysAsn: 0.951 ± 0.0
0.476CysPro: 0.476 ± 0.0
0.476CysGln: 0.476 ± 0.0
1.427CysArg: 1.427 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.951CysThr: 0.951 ± 0.0
0.951CysVal: 0.951 ± 0.0
0.238CysTrp: 0.238 ± 0.0
0.951CysTyr: 0.951 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.854AspAla: 2.854 ± 0.0
0.951AspCys: 0.951 ± 0.0
3.567AspAsp: 3.567 ± 0.0
3.567AspGlu: 3.567 ± 0.0
2.14AspPhe: 2.14 ± 0.0
2.378AspGly: 2.378 ± 0.0
0.951AspHis: 0.951 ± 0.0
3.092AspIle: 3.092 ± 0.0
4.756AspLys: 4.756 ± 0.0
5.707AspLeu: 5.707 ± 0.0
1.665AspMet: 1.665 ± 0.0
2.378AspAsn: 2.378 ± 0.0
1.902AspPro: 1.902 ± 0.0
2.14AspGln: 2.14 ± 0.0
3.805AspArg: 3.805 ± 0.0
3.092AspSer: 3.092 ± 0.0
2.14AspThr: 2.14 ± 0.0
5.47AspVal: 5.47 ± 0.0
0.0AspTrp: 0.0 ± 0.0
2.616AspTyr: 2.616 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.281GluAla: 4.281 ± 0.0
1.665GluCys: 1.665 ± 0.0
4.281GluAsp: 4.281 ± 0.0
6.421GluGlu: 6.421 ± 0.0
3.567GluPhe: 3.567 ± 0.0
3.092GluGly: 3.092 ± 0.0
0.476GluHis: 0.476 ± 0.0
4.281GluIle: 4.281 ± 0.0
3.092GluLys: 3.092 ± 0.0
4.756GluLeu: 4.756 ± 0.0
0.713GluMet: 0.713 ± 0.0
2.616GluAsn: 2.616 ± 0.0
0.951GluPro: 0.951 ± 0.0
1.902GluGln: 1.902 ± 0.0
1.427GluArg: 1.427 ± 0.0
4.281GluSer: 4.281 ± 0.0
5.707GluThr: 5.707 ± 0.0
4.043GluVal: 4.043 ± 0.0
0.951GluTrp: 0.951 ± 0.0
1.902GluTyr: 1.902 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.616PheAla: 2.616 ± 0.0
0.713PheCys: 0.713 ± 0.0
2.616PheAsp: 2.616 ± 0.0
2.616PheGlu: 2.616 ± 0.0
0.951PhePhe: 0.951 ± 0.0
4.043PheGly: 4.043 ± 0.0
2.14PheHis: 2.14 ± 0.0
1.665PheIle: 1.665 ± 0.0
2.616PheLys: 2.616 ± 0.0
2.854PheLeu: 2.854 ± 0.0
0.713PheMet: 0.713 ± 0.0
2.14PheAsn: 2.14 ± 0.0
0.713PhePro: 0.713 ± 0.0
1.665PheGln: 1.665 ± 0.0
2.854PheArg: 2.854 ± 0.0
3.567PheSer: 3.567 ± 0.0
4.043PheThr: 4.043 ± 0.0
1.665PheVal: 1.665 ± 0.0
0.238PheTrp: 0.238 ± 0.0
3.567PheTyr: 3.567 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.14GlyAla: 2.14 ± 0.0
0.951GlyCys: 0.951 ± 0.0
2.854GlyAsp: 2.854 ± 0.0
2.616GlyGlu: 2.616 ± 0.0
2.616GlyPhe: 2.616 ± 0.0
2.14GlyGly: 2.14 ± 0.0
1.189GlyHis: 1.189 ± 0.0
5.945GlyIle: 5.945 ± 0.0
4.518GlyLys: 4.518 ± 0.0
5.232GlyLeu: 5.232 ± 0.0
0.713GlyMet: 0.713 ± 0.0
1.665GlyAsn: 1.665 ± 0.0
2.14GlyPro: 2.14 ± 0.0
2.14GlyGln: 2.14 ± 0.0
4.281GlyArg: 4.281 ± 0.0
2.616GlySer: 2.616 ± 0.0
3.567GlyThr: 3.567 ± 0.0
2.854GlyVal: 2.854 ± 0.0
1.427GlyTrp: 1.427 ± 0.0
2.14GlyTyr: 2.14 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.189HisAla: 1.189 ± 0.0
0.476HisCys: 0.476 ± 0.0
0.476HisAsp: 0.476 ± 0.0
1.189HisGlu: 1.189 ± 0.0
1.427HisPhe: 1.427 ± 0.0
1.665HisGly: 1.665 ± 0.0
0.713HisHis: 0.713 ± 0.0
0.713HisIle: 0.713 ± 0.0
1.189HisLys: 1.189 ± 0.0
1.665HisLeu: 1.665 ± 0.0
1.665HisMet: 1.665 ± 0.0
0.713HisAsn: 0.713 ± 0.0
1.427HisPro: 1.427 ± 0.0
1.189HisGln: 1.189 ± 0.0
1.665HisArg: 1.665 ± 0.0
1.189HisSer: 1.189 ± 0.0
2.378HisThr: 2.378 ± 0.0
0.713HisVal: 0.713 ± 0.0
0.476HisTrp: 0.476 ± 0.0
1.189HisTyr: 1.189 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.805IleAla: 3.805 ± 0.0
0.713IleCys: 0.713 ± 0.0
1.665IleAsp: 1.665 ± 0.0
5.47IleGlu: 5.47 ± 0.0
3.329IlePhe: 3.329 ± 0.0
3.805IleGly: 3.805 ± 0.0
0.713IleHis: 0.713 ± 0.0
4.281IleIle: 4.281 ± 0.0
3.805IleLys: 3.805 ± 0.0
6.183IleLeu: 6.183 ± 0.0
1.427IleMet: 1.427 ± 0.0
4.994IleAsn: 4.994 ± 0.0
3.092IlePro: 3.092 ± 0.0
2.854IleGln: 2.854 ± 0.0
5.47IleArg: 5.47 ± 0.0
5.232IleSer: 5.232 ± 0.0
6.897IleThr: 6.897 ± 0.0
1.427IleVal: 1.427 ± 0.0
0.476IleTrp: 0.476 ± 0.0
3.329IleTyr: 3.329 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.805LysAla: 3.805 ± 0.0
0.713LysCys: 0.713 ± 0.0
2.616LysAsp: 2.616 ± 0.0
2.14LysGlu: 2.14 ± 0.0
3.567LysPhe: 3.567 ± 0.0
2.378LysGly: 2.378 ± 0.0
3.092LysHis: 3.092 ± 0.0
3.805LysIle: 3.805 ± 0.0
3.567LysLys: 3.567 ± 0.0
5.47LysLeu: 5.47 ± 0.0
2.14LysMet: 2.14 ± 0.0
3.092LysAsn: 3.092 ± 0.0
1.665LysPro: 1.665 ± 0.0
3.092LysGln: 3.092 ± 0.0
3.092LysArg: 3.092 ± 0.0
4.756LysSer: 4.756 ± 0.0
3.329LysThr: 3.329 ± 0.0
4.043LysVal: 4.043 ± 0.0
0.951LysTrp: 0.951 ± 0.0
1.902LysTyr: 1.902 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.421LeuAla: 6.421 ± 0.0
1.427LeuCys: 1.427 ± 0.0
4.756LeuAsp: 4.756 ± 0.0
4.281LeuGlu: 4.281 ± 0.0
2.378LeuPhe: 2.378 ± 0.0
3.567LeuGly: 3.567 ± 0.0
2.616LeuHis: 2.616 ± 0.0
3.805LeuIle: 3.805 ± 0.0
5.232LeuLys: 5.232 ± 0.0
4.281LeuLeu: 4.281 ± 0.0
2.854LeuMet: 2.854 ± 0.0
4.518LeuAsn: 4.518 ± 0.0
5.707LeuPro: 5.707 ± 0.0
3.329LeuGln: 3.329 ± 0.0
4.518LeuArg: 4.518 ± 0.0
7.61LeuSer: 7.61 ± 0.0
5.47LeuThr: 5.47 ± 0.0
4.281LeuVal: 4.281 ± 0.0
1.427LeuTrp: 1.427 ± 0.0
2.378LeuTyr: 2.378 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
0.951MetAla: 0.951 ± 0.0
1.189MetCys: 1.189 ± 0.0
1.427MetAsp: 1.427 ± 0.0
1.902MetGlu: 1.902 ± 0.0
1.427MetPhe: 1.427 ± 0.0
0.476MetGly: 0.476 ± 0.0
0.238MetHis: 0.238 ± 0.0
1.665MetIle: 1.665 ± 0.0
1.189MetLys: 1.189 ± 0.0
1.902MetLeu: 1.902 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.189MetAsn: 1.189 ± 0.0
1.427MetPro: 1.427 ± 0.0
0.476MetGln: 0.476 ± 0.0
1.902MetArg: 1.902 ± 0.0
3.567MetSer: 3.567 ± 0.0
1.189MetThr: 1.189 ± 0.0
1.189MetVal: 1.189 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.951MetTyr: 0.951 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.854AsnAla: 2.854 ± 0.0
0.951AsnCys: 0.951 ± 0.0
2.378AsnAsp: 2.378 ± 0.0
2.378AsnGlu: 2.378 ± 0.0
2.854AsnPhe: 2.854 ± 0.0
2.14AsnGly: 2.14 ± 0.0
0.713AsnHis: 0.713 ± 0.0
4.281AsnIle: 4.281 ± 0.0
2.378AsnLys: 2.378 ± 0.0
4.281AsnLeu: 4.281 ± 0.0
0.713AsnMet: 0.713 ± 0.0
1.189AsnAsn: 1.189 ± 0.0
2.616AsnPro: 2.616 ± 0.0
4.518AsnGln: 4.518 ± 0.0
1.427AsnArg: 1.427 ± 0.0
4.994AsnSer: 4.994 ± 0.0
3.092AsnThr: 3.092 ± 0.0
3.567AsnVal: 3.567 ± 0.0
0.476AsnTrp: 0.476 ± 0.0
3.329AsnTyr: 3.329 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.378ProAla: 2.378 ± 0.0
0.713ProCys: 0.713 ± 0.0
2.378ProAsp: 2.378 ± 0.0
2.854ProGlu: 2.854 ± 0.0
0.713ProPhe: 0.713 ± 0.0
2.854ProGly: 2.854 ± 0.0
1.189ProHis: 1.189 ± 0.0
3.805ProIle: 3.805 ± 0.0
2.14ProLys: 2.14 ± 0.0
1.427ProLeu: 1.427 ± 0.0
1.665ProMet: 1.665 ± 0.0
1.902ProAsn: 1.902 ± 0.0
1.902ProPro: 1.902 ± 0.0
2.14ProGln: 2.14 ± 0.0
0.951ProArg: 0.951 ± 0.0
3.092ProSer: 3.092 ± 0.0
2.378ProThr: 2.378 ± 0.0
1.427ProVal: 1.427 ± 0.0
0.476ProTrp: 0.476 ± 0.0
2.378ProTyr: 2.378 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.854GlnAla: 2.854 ± 0.0
0.0GlnCys: 0.0 ± 0.0
2.616GlnAsp: 2.616 ± 0.0
1.665GlnGlu: 1.665 ± 0.0
2.378GlnPhe: 2.378 ± 0.0
0.951GlnGly: 0.951 ± 0.0
0.951GlnHis: 0.951 ± 0.0
4.043GlnIle: 4.043 ± 0.0
2.616GlnLys: 2.616 ± 0.0
3.092GlnLeu: 3.092 ± 0.0
1.427GlnMet: 1.427 ± 0.0
2.854GlnAsn: 2.854 ± 0.0
1.665GlnPro: 1.665 ± 0.0
0.713GlnGln: 0.713 ± 0.0
1.427GlnArg: 1.427 ± 0.0
4.043GlnSer: 4.043 ± 0.0
2.616GlnThr: 2.616 ± 0.0
2.616GlnVal: 2.616 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
2.616GlnTyr: 2.616 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.616ArgAla: 2.616 ± 0.0
0.713ArgCys: 0.713 ± 0.0
2.616ArgAsp: 2.616 ± 0.0
2.378ArgGlu: 2.378 ± 0.0
2.14ArgPhe: 2.14 ± 0.0
3.092ArgGly: 3.092 ± 0.0
1.427ArgHis: 1.427 ± 0.0
3.092ArgIle: 3.092 ± 0.0
4.994ArgLys: 4.994 ± 0.0
3.567ArgLeu: 3.567 ± 0.0
1.427ArgMet: 1.427 ± 0.0
2.854ArgAsn: 2.854 ± 0.0
2.14ArgPro: 2.14 ± 0.0
2.378ArgGln: 2.378 ± 0.0
2.378ArgArg: 2.378 ± 0.0
3.092ArgSer: 3.092 ± 0.0
4.043ArgThr: 4.043 ± 0.0
3.567ArgVal: 3.567 ± 0.0
1.427ArgTrp: 1.427 ± 0.0
2.14ArgTyr: 2.14 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.616SerAla: 2.616 ± 0.0
0.238SerCys: 0.238 ± 0.0
5.232SerAsp: 5.232 ± 0.0
4.043SerGlu: 4.043 ± 0.0
2.378SerPhe: 2.378 ± 0.0
4.994SerGly: 4.994 ± 0.0
0.951SerHis: 0.951 ± 0.0
8.086SerIle: 8.086 ± 0.0
3.092SerLys: 3.092 ± 0.0
8.323SerLeu: 8.323 ± 0.0
0.951SerMet: 0.951 ± 0.0
4.281SerAsn: 4.281 ± 0.0
2.378SerPro: 2.378 ± 0.0
3.092SerGln: 3.092 ± 0.0
4.043SerArg: 4.043 ± 0.0
7.848SerSer: 7.848 ± 0.0
6.659SerThr: 6.659 ± 0.0
5.707SerVal: 5.707 ± 0.0
0.238SerTrp: 0.238 ± 0.0
4.518SerTyr: 4.518 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
6.421ThrAla: 6.421 ± 0.0
0.476ThrCys: 0.476 ± 0.0
4.994ThrAsp: 4.994 ± 0.0
3.329ThrGlu: 3.329 ± 0.0
2.378ThrPhe: 2.378 ± 0.0
4.518ThrGly: 4.518 ± 0.0
1.665ThrHis: 1.665 ± 0.0
6.659ThrIle: 6.659 ± 0.0
3.805ThrLys: 3.805 ± 0.0
6.183ThrLeu: 6.183 ± 0.0
1.427ThrMet: 1.427 ± 0.0
2.854ThrAsn: 2.854 ± 0.0
2.854ThrPro: 2.854 ± 0.0
2.14ThrGln: 2.14 ± 0.0
2.854ThrArg: 2.854 ± 0.0
8.086ThrSer: 8.086 ± 0.0
4.281ThrThr: 4.281 ± 0.0
3.567ThrVal: 3.567 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
4.756ThrTyr: 4.756 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.567ValAla: 3.567 ± 0.0
0.476ValCys: 0.476 ± 0.0
2.616ValAsp: 2.616 ± 0.0
4.043ValGlu: 4.043 ± 0.0
2.616ValPhe: 2.616 ± 0.0
3.805ValGly: 3.805 ± 0.0
0.951ValHis: 0.951 ± 0.0
4.281ValIle: 4.281 ± 0.0
2.854ValLys: 2.854 ± 0.0
4.281ValLeu: 4.281 ± 0.0
0.476ValMet: 0.476 ± 0.0
4.518ValAsn: 4.518 ± 0.0
2.14ValPro: 2.14 ± 0.0
3.329ValGln: 3.329 ± 0.0
2.14ValArg: 2.14 ± 0.0
3.329ValSer: 3.329 ± 0.0
5.232ValThr: 5.232 ± 0.0
5.232ValVal: 5.232 ± 0.0
0.238ValTrp: 0.238 ± 0.0
4.043ValTyr: 4.043 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.902TrpAla: 1.902 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.189TrpAsp: 1.189 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.951TrpPhe: 0.951 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.476TrpHis: 0.476 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.476TrpLys: 0.476 ± 0.0
0.476TrpLeu: 0.476 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.713TrpAsn: 0.713 ± 0.0
0.476TrpPro: 0.476 ± 0.0
0.476TrpGln: 0.476 ± 0.0
0.476TrpArg: 0.476 ± 0.0
0.951TrpSer: 0.951 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.951TrpVal: 0.951 ± 0.0
0.238TrpTrp: 0.238 ± 0.0
0.476TrpTyr: 0.476 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.616TyrAla: 2.616 ± 0.0
0.951TyrCys: 0.951 ± 0.0
3.329TyrAsp: 3.329 ± 0.0
5.232TyrGlu: 5.232 ± 0.0
1.902TyrPhe: 1.902 ± 0.0
2.854TyrGly: 2.854 ± 0.0
0.713TyrHis: 0.713 ± 0.0
1.427TyrIle: 1.427 ± 0.0
3.329TyrLys: 3.329 ± 0.0
4.756TyrLeu: 4.756 ± 0.0
0.951TyrMet: 0.951 ± 0.0
2.14TyrAsn: 2.14 ± 0.0
1.427TyrPro: 1.427 ± 0.0
1.427TyrGln: 1.427 ± 0.0
3.092TyrArg: 3.092 ± 0.0
3.092TyrSer: 3.092 ± 0.0
4.518TyrThr: 4.518 ± 0.0
2.616TyrVal: 2.616 ± 0.0
0.713TyrTrp: 0.713 ± 0.0
2.616TyrTyr: 2.616 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (4206 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski