Amino acid dipepetide frequency for Tobacco curly shoot virus - [Y41]

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.464AlaAla: 5.464 ± 1.264
1.821AlaCys: 1.821 ± 0.996
0.911AlaAsp: 0.911 ± 0.78
2.732AlaGlu: 2.732 ± 1.415
0.911AlaPhe: 0.911 ± 0.78
1.821AlaGly: 1.821 ± 1.559
2.732AlaHis: 2.732 ± 1.178
1.821AlaIle: 1.821 ± 1.268
3.643AlaLys: 3.643 ± 1.276
7.286AlaLeu: 7.286 ± 2.263
0.0AlaMet: 0.0 ± 0.0
2.732AlaAsn: 2.732 ± 1.025
3.643AlaPro: 3.643 ± 1.105
4.554AlaGln: 4.554 ± 1.396
5.464AlaArg: 5.464 ± 2.097
6.375AlaSer: 6.375 ± 1.593
2.732AlaThr: 2.732 ± 2.339
1.821AlaVal: 1.821 ± 1.454
1.821AlaTrp: 1.821 ± 0.678
0.911AlaTyr: 0.911 ± 0.634
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.821CysCys: 1.821 ± 1.906
0.0CysAsp: 0.0 ± 0.0
1.821CysGlu: 1.821 ± 1.082
0.0CysPhe: 0.0 ± 0.0
1.821CysGly: 1.821 ± 0.967
0.911CysHis: 0.911 ± 0.82
0.0CysIle: 0.0 ± 0.0
1.821CysLys: 1.821 ± 0.678
0.0CysLeu: 0.0 ± 0.0
2.732CysMet: 2.732 ± 1.257
0.911CysAsn: 0.911 ± 0.634
1.821CysPro: 1.821 ± 1.906
0.911CysGln: 0.911 ± 0.634
0.911CysArg: 0.911 ± 0.634
2.732CysSer: 2.732 ± 1.677
0.911CysThr: 0.911 ± 0.78
1.821CysVal: 1.821 ± 1.559
0.0CysTrp: 0.0 ± 0.0
0.911CysTyr: 0.911 ± 1.036
0.0CysXaa: 0.0 ± 0.0
Asp
1.821AspAla: 1.821 ± 1.268
0.0AspCys: 0.0 ± 0.0
1.821AspAsp: 1.821 ± 0.967
2.732AspGlu: 2.732 ± 1.056
2.732AspPhe: 2.732 ± 0.839
2.732AspGly: 2.732 ± 1.902
2.732AspHis: 2.732 ± 1.105
2.732AspIle: 2.732 ± 1.804
0.911AspLys: 0.911 ± 0.78
4.554AspLeu: 4.554 ± 2.085
0.0AspMet: 0.0 ± 0.0
1.821AspAsn: 1.821 ± 0.996
1.821AspPro: 1.821 ± 1.06
2.732AspGln: 2.732 ± 1.196
3.643AspArg: 3.643 ± 1.465
5.464AspSer: 5.464 ± 1.379
0.911AspThr: 0.911 ± 0.953
7.286AspVal: 7.286 ± 1.73
1.821AspTrp: 1.821 ± 0.967
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.554GluAla: 4.554 ± 1.606
0.0GluCys: 0.0 ± 0.0
2.732GluAsp: 2.732 ± 1.196
4.554GluGlu: 4.554 ± 2.561
3.643GluPhe: 3.643 ± 1.532
4.554GluGly: 4.554 ± 1.606
1.821GluHis: 1.821 ± 2.072
0.911GluIle: 0.911 ± 1.036
3.643GluLys: 3.643 ± 1.991
3.643GluLeu: 3.643 ± 1.328
0.0GluMet: 0.0 ± 0.0
4.554GluAsn: 4.554 ± 2.111
2.732GluPro: 2.732 ± 1.134
3.643GluGln: 3.643 ± 1.741
0.911GluArg: 0.911 ± 0.82
2.732GluSer: 2.732 ± 0.839
2.732GluThr: 2.732 ± 1.243
1.821GluVal: 1.821 ± 1.189
1.821GluTrp: 1.821 ± 0.967
0.911GluTyr: 0.911 ± 0.634
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.911PheCys: 0.911 ± 0.78
3.643PheAsp: 3.643 ± 1.357
2.732PheGlu: 2.732 ± 0.915
1.821PhePhe: 1.821 ± 0.678
0.911PheGly: 0.911 ± 0.78
2.732PheHis: 2.732 ± 1.463
1.821PheIle: 1.821 ± 0.967
3.643PheLys: 3.643 ± 2.844
7.286PheLeu: 7.286 ± 1.784
0.911PheMet: 0.911 ± 0.634
2.732PheAsn: 2.732 ± 2.157
0.911PhePro: 0.911 ± 0.953
2.732PheGln: 2.732 ± 1.415
2.732PheArg: 2.732 ± 1.243
0.911PheSer: 0.911 ± 0.992
2.732PheThr: 2.732 ± 1.677
3.643PheVal: 3.643 ± 1.357
0.0PheTrp: 0.0 ± 0.0
0.911PheTyr: 0.911 ± 0.78
0.0PheXaa: 0.0 ± 0.0
Gly
1.821GlyAla: 1.821 ± 1.268
2.732GlyCys: 2.732 ± 0.839
2.732GlyAsp: 2.732 ± 1.415
3.643GlyGlu: 3.643 ± 1.121
1.821GlyPhe: 1.821 ± 1.145
2.732GlyGly: 2.732 ± 1.056
1.821GlyHis: 1.821 ± 1.06
2.732GlyIle: 2.732 ± 1.168
6.375GlyLys: 6.375 ± 2.598
2.732GlyLeu: 2.732 ± 1.311
0.0GlyMet: 0.0 ± 0.0
0.911GlyAsn: 0.911 ± 0.82
3.643GlyPro: 3.643 ± 1.222
0.911GlyGln: 0.911 ± 0.78
1.821GlyArg: 1.821 ± 0.904
2.732GlySer: 2.732 ± 1.415
3.643GlyThr: 3.643 ± 0.901
1.821GlyVal: 1.821 ± 2.072
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.732HisAla: 2.732 ± 1.628
2.732HisCys: 2.732 ± 1.178
2.732HisAsp: 2.732 ± 1.134
2.732HisGlu: 2.732 ± 1.178
2.732HisPhe: 2.732 ± 1.463
2.732HisGly: 2.732 ± 1.178
1.821HisHis: 1.821 ± 1.64
2.732HisIle: 2.732 ± 1.485
0.911HisLys: 0.911 ± 1.036
1.821HisLeu: 1.821 ± 1.268
0.911HisMet: 0.911 ± 0.992
2.732HisAsn: 2.732 ± 1.415
2.732HisPro: 2.732 ± 1.275
1.821HisGln: 1.821 ± 1.454
3.643HisArg: 3.643 ± 1.991
1.821HisSer: 1.821 ± 0.996
1.821HisThr: 1.821 ± 1.189
1.821HisVal: 1.821 ± 0.904
0.0HisTrp: 0.0 ± 0.0
0.911HisTyr: 0.911 ± 0.634
0.0HisXaa: 0.0 ± 0.0
Ile
0.911IleAla: 0.911 ± 0.82
1.821IleCys: 1.821 ± 1.06
1.821IleAsp: 1.821 ± 1.268
2.732IleGlu: 2.732 ± 1.168
3.643IlePhe: 3.643 ± 2.536
0.911IleGly: 0.911 ± 0.78
0.0IleHis: 0.0 ± 0.0
4.554IleIle: 4.554 ± 3.367
4.554IleLys: 4.554 ± 0.851
0.911IleLeu: 0.911 ± 0.634
0.911IleMet: 0.911 ± 0.992
3.643IleAsn: 3.643 ± 1.647
0.911IlePro: 0.911 ± 0.634
6.375IleGln: 6.375 ± 2.521
5.464IleArg: 5.464 ± 1.822
6.375IleSer: 6.375 ± 1.757
1.821IleThr: 1.821 ± 2.072
2.732IleVal: 2.732 ± 0.866
2.732IleTrp: 2.732 ± 2.157
2.732IleTyr: 2.732 ± 1.485
0.0IleXaa: 0.0 ± 0.0
Lys
6.375LysAla: 6.375 ± 1.146
0.911LysCys: 0.911 ± 1.036
2.732LysAsp: 2.732 ± 1.471
6.375LysGlu: 6.375 ± 1.146
3.643LysPhe: 3.643 ± 0.864
2.732LysGly: 2.732 ± 1.677
2.732LysHis: 2.732 ± 1.275
2.732LysIle: 2.732 ± 1.804
2.732LysLys: 2.732 ± 1.311
1.821LysLeu: 1.821 ± 1.082
0.911LysMet: 0.911 ± 0.992
7.286LysAsn: 7.286 ± 2.124
2.732LysPro: 2.732 ± 1.317
0.0LysGln: 0.0 ± 0.0
1.821LysArg: 1.821 ± 1.559
4.554LysSer: 4.554 ± 1.654
7.286LysThr: 7.286 ± 2.054
4.554LysVal: 4.554 ± 1.972
0.911LysTrp: 0.911 ± 0.78
3.643LysTyr: 3.643 ± 1.121
0.0LysXaa: 0.0 ± 0.0
Leu
2.732LeuAla: 2.732 ± 1.749
1.821LeuCys: 1.821 ± 1.268
5.464LeuAsp: 5.464 ± 3.166
3.643LeuGlu: 3.643 ± 1.328
1.821LeuPhe: 1.821 ± 0.967
5.464LeuGly: 5.464 ± 1.882
1.821LeuHis: 1.821 ± 1.268
4.554LeuIle: 4.554 ± 2.063
6.375LeuLys: 6.375 ± 2.163
0.911LeuLeu: 0.911 ± 0.992
2.732LeuMet: 2.732 ± 1.353
3.643LeuAsn: 3.643 ± 0.864
2.732LeuPro: 2.732 ± 1.875
2.732LeuGln: 2.732 ± 1.178
6.375LeuArg: 6.375 ± 1.641
3.643LeuSer: 3.643 ± 1.967
4.554LeuThr: 4.554 ± 1.655
3.643LeuVal: 3.643 ± 2.182
0.911LeuTrp: 0.911 ± 1.036
2.732LeuTyr: 2.732 ± 0.866
0.0LeuXaa: 0.0 ± 0.0
Met
1.821MetAla: 1.821 ± 0.678
0.911MetCys: 0.911 ± 0.78
1.821MetAsp: 1.821 ± 1.247
2.732MetGlu: 2.732 ± 1.977
1.821MetPhe: 1.821 ± 1.559
2.732MetGly: 2.732 ± 1.243
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.821MetLys: 1.821 ± 1.379
3.643MetLeu: 3.643 ± 1.29
0.0MetMet: 0.0 ± 0.0
0.911MetAsn: 0.911 ± 0.78
0.911MetPro: 0.911 ± 0.992
0.0MetGln: 0.0 ± 0.0
0.911MetArg: 0.911 ± 0.82
2.732MetSer: 2.732 ± 1.025
0.911MetThr: 0.911 ± 1.036
0.0MetVal: 0.0 ± 0.0
1.821MetTrp: 1.821 ± 1.06
1.821MetTyr: 1.821 ± 1.559
0.0MetXaa: 0.0 ± 0.0
Asn
2.732AsnAla: 2.732 ± 1.056
0.0AsnCys: 0.0 ± 0.0
1.821AsnAsp: 1.821 ± 1.268
1.821AsnGlu: 1.821 ± 1.082
0.911AsnPhe: 0.911 ± 0.78
0.911AsnGly: 0.911 ± 1.036
3.643AsnHis: 3.643 ± 1.573
3.643AsnIle: 3.643 ± 0.864
1.821AsnLys: 1.821 ± 1.268
5.464AsnLeu: 5.464 ± 1.889
1.821AsnMet: 1.821 ± 1.442
3.643AsnAsn: 3.643 ± 1.785
2.732AsnPro: 2.732 ± 0.866
2.732AsnGln: 2.732 ± 1.056
4.554AsnArg: 4.554 ± 2.129
5.464AsnSer: 5.464 ± 2.206
2.732AsnThr: 2.732 ± 1.415
3.643AsnVal: 3.643 ± 0.864
0.911AsnTrp: 0.911 ± 0.634
4.554AsnTyr: 4.554 ± 1.033
0.0AsnXaa: 0.0 ± 0.0
Pro
2.732ProAla: 2.732 ± 1.589
2.732ProCys: 2.732 ± 1.134
2.732ProAsp: 2.732 ± 1.276
2.732ProGlu: 2.732 ± 1.178
1.821ProPhe: 1.821 ± 0.904
0.911ProGly: 0.911 ± 0.634
4.554ProHis: 4.554 ± 2.567
4.554ProIle: 4.554 ± 1.069
2.732ProLys: 2.732 ± 1.471
4.554ProLeu: 4.554 ± 1.423
1.821ProMet: 1.821 ± 0.678
4.554ProAsn: 4.554 ± 2.339
2.732ProPro: 2.732 ± 1.463
2.732ProGln: 2.732 ± 1.485
3.643ProArg: 3.643 ± 1.711
4.554ProSer: 4.554 ± 1.744
2.732ProThr: 2.732 ± 1.471
2.732ProVal: 2.732 ± 1.317
0.0ProTrp: 0.0 ± 0.0
0.911ProTyr: 0.911 ± 0.78
0.0ProXaa: 0.0 ± 0.0
Gln
3.643GlnAla: 3.643 ± 1.121
0.911GlnCys: 0.911 ± 0.634
3.643GlnAsp: 3.643 ± 1.843
1.821GlnGlu: 1.821 ± 0.678
2.732GlnPhe: 2.732 ± 1.168
1.821GlnGly: 1.821 ± 1.082
1.821GlnHis: 1.821 ± 1.189
3.643GlnIle: 3.643 ± 1.647
1.821GlnLys: 1.821 ± 1.906
2.732GlnLeu: 2.732 ± 1.941
1.821GlnMet: 1.821 ± 1.256
1.821GlnAsn: 1.821 ± 2.072
3.643GlnPro: 3.643 ± 1.67
1.821GlnGln: 1.821 ± 1.189
1.821GlnArg: 1.821 ± 1.268
6.375GlnSer: 6.375 ± 1.157
1.821GlnThr: 1.821 ± 0.904
3.643GlnVal: 3.643 ± 0.93
0.0GlnTrp: 0.0 ± 0.0
0.911GlnTyr: 0.911 ± 0.78
0.0GlnXaa: 0.0 ± 0.0
Arg
4.554ArgAla: 4.554 ± 1.817
0.911ArgCys: 0.911 ± 0.953
3.643ArgAsp: 3.643 ± 1.329
2.732ArgGlu: 2.732 ± 1.471
3.643ArgPhe: 3.643 ± 1.121
3.643ArgGly: 3.643 ± 1.3
2.732ArgHis: 2.732 ± 1.134
4.554ArgIle: 4.554 ± 1.244
2.732ArgLys: 2.732 ± 1.804
2.732ArgLeu: 2.732 ± 1.311
1.821ArgMet: 1.821 ± 1.559
0.911ArgAsn: 0.911 ± 0.953
6.375ArgPro: 6.375 ± 1.739
1.821ArgGln: 1.821 ± 1.242
6.375ArgArg: 6.375 ± 3.572
5.464ArgSer: 5.464 ± 1.62
2.732ArgThr: 2.732 ± 1.196
5.464ArgVal: 5.464 ± 2.62
0.0ArgTrp: 0.0 ± 0.0
1.821ArgTyr: 1.821 ± 1.082
0.0ArgXaa: 0.0 ± 0.0
Ser
5.464SerAla: 5.464 ± 3.166
0.911SerCys: 0.911 ± 0.634
1.821SerAsp: 1.821 ± 0.996
1.821SerGlu: 1.821 ± 0.678
2.732SerPhe: 2.732 ± 0.839
2.732SerGly: 2.732 ± 1.415
1.821SerHis: 1.821 ± 1.256
7.286SerIle: 7.286 ± 4.12
8.197SerLys: 8.197 ± 2.405
3.643SerLeu: 3.643 ± 1.574
1.821SerMet: 1.821 ± 1.853
4.554SerAsn: 4.554 ± 1.655
8.197SerPro: 8.197 ± 1.954
3.643SerGln: 3.643 ± 1.424
5.464SerArg: 5.464 ± 1.403
14.572SerSer: 14.572 ± 6.05
3.643SerThr: 3.643 ± 1.3
4.554SerVal: 4.554 ± 2.333
0.0SerTrp: 0.0 ± 0.0
2.732SerTyr: 2.732 ± 1.105
0.0SerXaa: 0.0 ± 0.0
Thr
3.643ThrAla: 3.643 ± 0.93
0.911ThrCys: 0.911 ± 0.992
0.911ThrAsp: 0.911 ± 0.634
0.911ThrGlu: 0.911 ± 0.992
0.911ThrPhe: 0.911 ± 0.992
3.643ThrGly: 3.643 ± 1.785
4.554ThrHis: 4.554 ± 2.106
1.821ThrIle: 1.821 ± 0.904
4.554ThrLys: 4.554 ± 1.428
2.732ThrLeu: 2.732 ± 0.915
0.911ThrMet: 0.911 ± 0.634
1.821ThrAsn: 1.821 ± 1.559
4.554ThrPro: 4.554 ± 1.606
2.732ThrGln: 2.732 ± 1.545
1.821ThrArg: 1.821 ± 0.678
3.643ThrSer: 3.643 ± 1.328
0.911ThrThr: 0.911 ± 0.992
3.643ThrVal: 3.643 ± 1.573
0.911ThrTrp: 0.911 ± 0.992
2.732ThrTyr: 2.732 ± 1.463
0.0ThrXaa: 0.0 ± 0.0
Val
1.821ValAla: 1.821 ± 1.189
0.0ValCys: 0.0 ± 0.0
4.554ValAsp: 4.554 ± 1.782
1.821ValGlu: 1.821 ± 1.906
2.732ValPhe: 2.732 ± 2.157
0.911ValGly: 0.911 ± 0.78
2.732ValHis: 2.732 ± 1.5
3.643ValIle: 3.643 ± 1.424
6.375ValLys: 6.375 ± 1.765
6.375ValLeu: 6.375 ± 1.609
1.821ValMet: 1.821 ± 1.559
1.821ValAsn: 1.821 ± 1.082
2.732ValPro: 2.732 ± 0.839
4.554ValGln: 4.554 ± 1.654
3.643ValArg: 3.643 ± 3.118
2.732ValSer: 2.732 ± 1.317
3.643ValThr: 3.643 ± 2.055
1.821ValVal: 1.821 ± 0.678
0.0ValTrp: 0.0 ± 0.0
7.286ValTyr: 7.286 ± 3.172
0.0ValXaa: 0.0 ± 0.0
Trp
3.643TrpAla: 3.643 ± 1.605
0.0TrpCys: 0.0 ± 0.0
1.821TrpAsp: 1.821 ± 1.454
0.911TrpGlu: 0.911 ± 1.036
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.911TrpHis: 0.911 ± 0.78
0.0TrpIle: 0.0 ± 0.0
0.911TrpLys: 0.911 ± 0.992
0.0TrpLeu: 0.0 ± 0.0
1.821TrpMet: 1.821 ± 1.247
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.911TrpGln: 0.911 ± 0.634
0.911TrpArg: 0.911 ± 0.82
0.911TrpSer: 0.911 ± 0.82
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.911TrpTyr: 0.911 ± 0.634
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.732TyrAla: 2.732 ± 1.317
0.0TyrCys: 0.0 ± 0.0
0.911TyrAsp: 0.911 ± 0.78
0.911TyrGlu: 0.911 ± 0.78
3.643TyrPhe: 3.643 ± 0.93
0.911TyrGly: 0.911 ± 0.634
0.0TyrHis: 0.0 ± 0.0
1.821TyrIle: 1.821 ± 0.904
0.911TyrLys: 0.911 ± 0.634
5.464TyrLeu: 5.464 ± 1.983
3.643TyrMet: 3.643 ± 0.953
4.554TyrAsn: 4.554 ± 1.033
0.911TyrPro: 0.911 ± 0.634
0.911TyrGln: 0.911 ± 0.78
2.732TyrArg: 2.732 ± 1.804
2.732TyrSer: 2.732 ± 1.292
0.0TyrThr: 0.0 ± 0.0
4.554TyrVal: 4.554 ± 2.484
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1099 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski