Amino acid dipepetide frequency for Beihai charybdis crab virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.271AlaAla: 6.271 ± 11.34
3.377AlaCys: 3.377 ± 1.353
3.859AlaAsp: 3.859 ± 1.664
5.789AlaGlu: 5.789 ± 5.931
3.377AlaPhe: 3.377 ± 1.353
1.447AlaGly: 1.447 ± 0.624
0.965AlaHis: 0.965 ± 0.416
2.412AlaIle: 2.412 ± 1.04
2.894AlaLys: 2.894 ± 1.561
7.236AlaLeu: 7.236 ± 2.498
0.965AlaMet: 0.965 ± 0.416
2.412AlaAsn: 2.412 ± 1.04
2.894AlaPro: 2.894 ± 7.178
1.447AlaGln: 1.447 ± 2.185
6.271AlaArg: 6.271 ± 2.914
6.271AlaSer: 6.271 ± 0.105
3.377AlaThr: 3.377 ± 1.353
2.894AlaVal: 2.894 ± 1.561
0.482AlaTrp: 0.482 ± 0.208
4.342AlaTyr: 4.342 ± 1.872
0.0AlaXaa: 0.0 ± 0.0
Cys
1.447CysAla: 1.447 ± 0.624
0.482CysCys: 0.482 ± 0.208
0.965CysAsp: 0.965 ± 0.416
1.93CysGlu: 1.93 ± 0.832
0.965CysPhe: 0.965 ± 0.416
1.447CysGly: 1.447 ± 2.185
0.482CysHis: 0.482 ± 0.208
1.447CysIle: 1.447 ± 0.624
0.965CysLys: 0.965 ± 0.416
2.894CysLeu: 2.894 ± 1.248
0.482CysMet: 0.482 ± 0.208
0.0CysAsn: 0.0 ± 0.0
0.965CysPro: 0.965 ± 0.416
0.0CysGln: 0.0 ± 0.0
0.965CysArg: 0.965 ± 0.416
1.93CysSer: 1.93 ± 0.832
0.965CysThr: 0.965 ± 0.416
1.447CysVal: 1.447 ± 0.624
0.0CysTrp: 0.0 ± 0.0
0.482CysTyr: 0.482 ± 0.208
0.0CysXaa: 0.0 ± 0.0
Asp
3.859AspAla: 3.859 ± 1.145
0.0AspCys: 0.0 ± 0.0
4.342AspAsp: 4.342 ± 1.872
4.824AspGlu: 4.824 ± 2.08
3.377AspPhe: 3.377 ± 1.456
3.377AspGly: 3.377 ± 1.456
0.965AspHis: 0.965 ± 0.416
2.894AspIle: 2.894 ± 1.248
4.342AspLys: 4.342 ± 1.872
7.718AspLeu: 7.718 ± 3.328
0.482AspMet: 0.482 ± 0.208
3.377AspAsn: 3.377 ± 1.456
2.412AspPro: 2.412 ± 1.04
1.93AspGln: 1.93 ± 0.832
5.306AspArg: 5.306 ± 0.521
3.377AspSer: 3.377 ± 1.456
2.412AspThr: 2.412 ± 1.04
6.271AspVal: 6.271 ± 0.105
0.482AspTrp: 0.482 ± 2.601
1.447AspTyr: 1.447 ± 0.624
0.0AspXaa: 0.0 ± 0.0
Glu
4.824GluAla: 4.824 ± 6.346
2.412GluCys: 2.412 ± 1.04
4.824GluAsp: 4.824 ± 2.08
6.271GluGlu: 6.271 ± 2.914
1.447GluPhe: 1.447 ± 0.624
4.824GluGly: 4.824 ± 2.08
1.447GluHis: 1.447 ± 4.994
4.342GluIle: 4.342 ± 0.937
3.859GluLys: 3.859 ± 1.145
6.271GluLeu: 6.271 ± 2.914
2.412GluMet: 2.412 ± 1.769
3.859GluAsn: 3.859 ± 1.145
3.859GluPro: 3.859 ± 1.664
0.965GluGln: 0.965 ± 0.416
4.824GluArg: 4.824 ± 3.538
2.894GluSer: 2.894 ± 1.248
4.342GluThr: 4.342 ± 1.872
2.412GluVal: 2.412 ± 1.04
0.965GluTrp: 0.965 ± 0.416
1.93GluTyr: 1.93 ± 0.832
0.0GluXaa: 0.0 ± 0.0
Phe
2.894PheAla: 2.894 ± 1.561
1.447PheCys: 1.447 ± 0.624
3.859PheAsp: 3.859 ± 1.664
1.447PheGlu: 1.447 ± 2.185
2.412PhePhe: 2.412 ± 1.04
1.447PheGly: 1.447 ± 2.185
0.965PheHis: 0.965 ± 0.416
2.412PheIle: 2.412 ± 1.04
4.824PheLys: 4.824 ± 2.08
3.377PheLeu: 3.377 ± 1.456
0.965PheMet: 0.965 ± 0.416
1.447PheAsn: 1.447 ± 0.624
2.894PhePro: 2.894 ± 1.561
0.482PheGln: 0.482 ± 0.208
3.859PheArg: 3.859 ± 1.664
5.789PheSer: 5.789 ± 3.122
3.377PheThr: 3.377 ± 1.456
0.965PheVal: 0.965 ± 0.416
1.447PheTrp: 1.447 ± 2.185
1.93PheTyr: 1.93 ± 0.832
0.0PheXaa: 0.0 ± 0.0
Gly
4.824GlyAla: 4.824 ± 2.08
0.482GlyCys: 0.482 ± 0.208
4.342GlyAsp: 4.342 ± 0.937
6.753GlyGlu: 6.753 ± 0.103
2.412GlyPhe: 2.412 ± 1.04
3.377GlyGly: 3.377 ± 1.353
1.93GlyHis: 1.93 ± 4.786
1.447GlyIle: 1.447 ± 0.624
2.894GlyLys: 2.894 ± 1.248
3.377GlyLeu: 3.377 ± 1.353
0.482GlyMet: 0.482 ± 0.208
1.447GlyAsn: 1.447 ± 0.624
1.447GlyPro: 1.447 ± 0.624
0.482GlyGln: 0.482 ± 0.208
2.412GlyArg: 2.412 ± 1.04
1.93GlySer: 1.93 ± 0.832
3.377GlyThr: 3.377 ± 1.456
2.894GlyVal: 2.894 ± 1.248
0.482GlyTrp: 0.482 ± 0.208
2.894GlyTyr: 2.894 ± 1.561
0.0GlyXaa: 0.0 ± 0.0
His
0.482HisAla: 0.482 ± 0.208
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.93HisGlu: 1.93 ± 1.977
0.482HisPhe: 0.482 ± 0.208
0.965HisGly: 0.965 ± 0.416
1.447HisHis: 1.447 ± 0.624
1.93HisIle: 1.93 ± 1.977
0.0HisLys: 0.0 ± 0.0
2.412HisLeu: 2.412 ± 1.769
0.0HisMet: 0.0 ± 0.0
0.965HisAsn: 0.965 ± 0.416
1.447HisPro: 1.447 ± 0.624
0.482HisGln: 0.482 ± 0.208
0.965HisArg: 0.965 ± 0.416
2.412HisSer: 2.412 ± 1.04
2.412HisThr: 2.412 ± 1.04
2.894HisVal: 2.894 ± 1.561
0.0HisTrp: 0.0 ± 0.0
0.482HisTyr: 0.482 ± 0.208
0.0HisXaa: 0.0 ± 0.0
Ile
3.377IleAla: 3.377 ± 1.456
0.482IleCys: 0.482 ± 0.208
4.824IleAsp: 4.824 ± 2.08
3.377IleGlu: 3.377 ± 1.456
0.965IlePhe: 0.965 ± 0.416
1.447IleGly: 1.447 ± 2.185
0.965IleHis: 0.965 ± 0.416
1.447IleIle: 1.447 ± 0.624
4.342IleLys: 4.342 ± 1.872
2.894IleLeu: 2.894 ± 1.248
0.965IleMet: 0.965 ± 0.416
2.894IleAsn: 2.894 ± 1.561
1.93IlePro: 1.93 ± 0.832
0.965IleGln: 0.965 ± 2.393
2.412IleArg: 2.412 ± 1.769
3.859IleSer: 3.859 ± 1.664
5.789IleThr: 5.789 ± 2.496
6.271IleVal: 6.271 ± 0.105
0.0IleTrp: 0.0 ± 0.0
1.447IleTyr: 1.447 ± 0.624
0.0IleXaa: 0.0 ± 0.0
Lys
7.236LysAla: 7.236 ± 0.311
0.965LysCys: 0.965 ± 0.416
3.859LysAsp: 3.859 ± 1.664
3.377LysGlu: 3.377 ± 1.456
3.377LysPhe: 3.377 ± 1.353
3.377LysGly: 3.377 ± 1.456
0.482LysHis: 0.482 ± 0.208
2.894LysIle: 2.894 ± 1.248
3.377LysLys: 3.377 ± 1.456
6.753LysLeu: 6.753 ± 2.912
0.482LysMet: 0.482 ± 2.601
2.894LysAsn: 2.894 ± 4.37
1.93LysPro: 1.93 ± 0.832
2.412LysGln: 2.412 ± 1.04
4.342LysArg: 4.342 ± 1.872
4.824LysSer: 4.824 ± 2.08
1.93LysThr: 1.93 ± 0.832
4.824LysVal: 4.824 ± 2.08
0.0LysTrp: 0.0 ± 0.0
1.447LysTyr: 1.447 ± 0.624
0.0LysXaa: 0.0 ± 0.0
Leu
4.342LeuAla: 4.342 ± 3.746
0.965LeuCys: 0.965 ± 0.416
4.342LeuAsp: 4.342 ± 1.872
5.789LeuGlu: 5.789 ± 0.313
5.789LeuPhe: 5.789 ± 2.496
4.824LeuGly: 4.824 ± 2.08
0.0LeuHis: 0.0 ± 0.0
4.824LeuIle: 4.824 ± 0.729
6.753LeuLys: 6.753 ± 0.103
8.201LeuLeu: 8.201 ± 0.727
2.412LeuMet: 2.412 ± 1.04
3.377LeuAsn: 3.377 ± 1.353
4.342LeuPro: 4.342 ± 0.937
2.894LeuGln: 2.894 ± 1.561
4.342LeuArg: 4.342 ± 1.872
6.753LeuSer: 6.753 ± 2.912
7.718LeuThr: 7.718 ± 2.29
5.789LeuVal: 5.789 ± 2.496
0.0LeuTrp: 0.0 ± 0.0
3.859LeuTyr: 3.859 ± 1.664
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.482MetCys: 0.482 ± 0.208
0.482MetAsp: 0.482 ± 0.208
0.0MetGlu: 0.0 ± 0.0
2.894MetPhe: 2.894 ± 1.248
0.0MetGly: 0.0 ± 0.0
1.447MetHis: 1.447 ± 0.624
1.447MetIle: 1.447 ± 0.624
0.482MetLys: 0.482 ± 0.208
1.447MetLeu: 1.447 ± 4.994
0.482MetMet: 0.482 ± 0.208
0.0MetAsn: 0.0 ± 0.0
0.482MetPro: 0.482 ± 2.601
0.965MetGln: 0.965 ± 0.416
0.965MetArg: 0.965 ± 0.416
2.894MetSer: 2.894 ± 1.248
0.482MetThr: 0.482 ± 0.208
0.482MetVal: 0.482 ± 0.208
0.0MetTrp: 0.0 ± 0.0
1.447MetTyr: 1.447 ± 0.624
0.0MetXaa: 0.0 ± 0.0
Asn
2.412AsnAla: 2.412 ± 1.769
0.482AsnCys: 0.482 ± 0.208
2.894AsnAsp: 2.894 ± 1.561
0.965AsnGlu: 0.965 ± 0.416
2.412AsnPhe: 2.412 ± 1.769
1.93AsnGly: 1.93 ± 1.977
0.965AsnHis: 0.965 ± 0.416
1.93AsnIle: 1.93 ± 1.977
1.93AsnLys: 1.93 ± 0.832
2.894AsnLeu: 2.894 ± 1.248
0.0AsnMet: 0.0 ± 0.0
1.447AsnAsn: 1.447 ± 0.624
0.965AsnPro: 0.965 ± 2.393
0.965AsnGln: 0.965 ± 2.393
1.93AsnArg: 1.93 ± 1.977
5.306AsnSer: 5.306 ± 2.288
4.342AsnThr: 4.342 ± 0.937
4.342AsnVal: 4.342 ± 1.872
0.965AsnTrp: 0.965 ± 2.393
1.447AsnTyr: 1.447 ± 0.624
0.0AsnXaa: 0.0 ± 0.0
Pro
1.93ProAla: 1.93 ± 0.832
0.0ProCys: 0.0 ± 0.0
1.93ProAsp: 1.93 ± 0.832
4.342ProGlu: 4.342 ± 0.937
1.447ProPhe: 1.447 ± 2.185
4.342ProGly: 4.342 ± 0.937
1.447ProHis: 1.447 ± 0.624
2.894ProIle: 2.894 ± 1.248
3.377ProLys: 3.377 ± 1.456
2.894ProLeu: 2.894 ± 1.248
0.965ProMet: 0.965 ± 0.988
1.93ProAsn: 1.93 ± 1.977
3.377ProPro: 3.377 ± 1.456
2.412ProGln: 2.412 ± 1.04
2.894ProArg: 2.894 ± 1.248
3.377ProSer: 3.377 ± 1.456
2.894ProThr: 2.894 ± 1.561
1.93ProVal: 1.93 ± 0.832
0.482ProTrp: 0.482 ± 2.601
2.412ProTyr: 2.412 ± 1.769
0.0ProXaa: 0.0 ± 0.0
Gln
3.859GlnAla: 3.859 ± 6.762
0.482GlnCys: 0.482 ± 0.208
2.412GlnAsp: 2.412 ± 1.04
3.859GlnGlu: 3.859 ± 1.145
1.93GlnPhe: 1.93 ± 1.977
1.93GlnGly: 1.93 ± 0.832
0.0GlnHis: 0.0 ± 0.0
2.412GlnIle: 2.412 ± 1.04
1.93GlnLys: 1.93 ± 0.832
1.447GlnLeu: 1.447 ± 2.185
1.447GlnMet: 1.447 ± 0.624
1.447GlnAsn: 1.447 ± 0.624
0.482GlnPro: 0.482 ± 0.208
0.965GlnGln: 0.965 ± 0.416
3.377GlnArg: 3.377 ± 1.456
0.965GlnSer: 0.965 ± 2.393
1.447GlnThr: 1.447 ± 0.624
1.447GlnVal: 1.447 ± 0.624
0.0GlnTrp: 0.0 ± 0.0
0.482GlnTyr: 0.482 ± 0.208
0.0GlnXaa: 0.0 ± 0.0
Arg
5.789ArgAla: 5.789 ± 5.931
1.93ArgCys: 1.93 ± 0.832
4.824ArgAsp: 4.824 ± 0.729
4.342ArgGlu: 4.342 ± 0.937
3.377ArgPhe: 3.377 ± 1.353
1.447ArgGly: 1.447 ± 0.624
1.93ArgHis: 1.93 ± 0.832
2.412ArgIle: 2.412 ± 1.04
4.342ArgLys: 4.342 ± 1.872
6.271ArgLeu: 6.271 ± 2.704
0.965ArgMet: 0.965 ± 0.416
3.377ArgAsn: 3.377 ± 1.353
2.894ArgPro: 2.894 ± 1.248
3.377ArgGln: 3.377 ± 1.353
5.306ArgArg: 5.306 ± 3.33
5.306ArgSer: 5.306 ± 0.521
2.894ArgThr: 2.894 ± 1.248
4.342ArgVal: 4.342 ± 1.872
1.447ArgTrp: 1.447 ± 2.185
0.482ArgTyr: 0.482 ± 0.208
0.0ArgXaa: 0.0 ± 0.0
Ser
1.93SerAla: 1.93 ± 0.832
1.93SerCys: 1.93 ± 0.832
3.377SerAsp: 3.377 ± 1.456
2.894SerGlu: 2.894 ± 1.248
3.859SerPhe: 3.859 ± 1.145
2.894SerGly: 2.894 ± 1.248
0.965SerHis: 0.965 ± 0.416
3.377SerIle: 3.377 ± 1.353
4.824SerLys: 4.824 ± 2.08
8.683SerLeu: 8.683 ± 3.744
1.447SerMet: 1.447 ± 0.624
3.859SerAsn: 3.859 ± 1.145
4.824SerPro: 4.824 ± 2.08
3.859SerGln: 3.859 ± 1.145
6.753SerArg: 6.753 ± 2.706
9.648SerSer: 9.648 ± 4.16
5.789SerThr: 5.789 ± 2.496
5.306SerVal: 5.306 ± 0.521
0.0SerTrp: 0.0 ± 0.0
2.894SerTyr: 2.894 ± 1.248
0.0SerXaa: 0.0 ± 0.0
Thr
3.859ThrAla: 3.859 ± 1.145
2.894ThrCys: 2.894 ± 1.248
3.377ThrAsp: 3.377 ± 1.456
3.377ThrGlu: 3.377 ± 1.353
2.412ThrPhe: 2.412 ± 1.04
3.859ThrGly: 3.859 ± 1.664
0.965ThrHis: 0.965 ± 0.416
4.824ThrIle: 4.824 ± 2.08
3.859ThrLys: 3.859 ± 1.145
4.342ThrLeu: 4.342 ± 1.872
0.0ThrMet: 0.0 ± 0.0
1.93ThrAsn: 1.93 ± 1.977
2.894ThrPro: 2.894 ± 1.248
2.412ThrGln: 2.412 ± 1.04
4.824ThrArg: 4.824 ± 0.729
3.859ThrSer: 3.859 ± 1.664
5.789ThrThr: 5.789 ± 0.313
5.306ThrVal: 5.306 ± 0.521
0.965ThrTrp: 0.965 ± 2.393
3.859ThrTyr: 3.859 ± 1.664
0.0ThrXaa: 0.0 ± 0.0
Val
6.753ValAla: 6.753 ± 2.912
0.482ValCys: 0.482 ± 0.208
4.342ValAsp: 4.342 ± 1.872
5.306ValGlu: 5.306 ± 3.33
2.412ValPhe: 2.412 ± 1.04
4.824ValGly: 4.824 ± 2.08
2.894ValHis: 2.894 ± 1.248
2.894ValIle: 2.894 ± 1.248
1.447ValLys: 1.447 ± 0.624
5.306ValLeu: 5.306 ± 0.521
0.965ValMet: 0.965 ± 0.416
2.894ValAsn: 2.894 ± 1.248
5.789ValPro: 5.789 ± 0.313
2.412ValGln: 2.412 ± 1.04
3.377ValArg: 3.377 ± 1.456
3.859ValSer: 3.859 ± 1.664
4.342ValThr: 4.342 ± 0.937
2.412ValVal: 2.412 ± 1.04
0.965ValTrp: 0.965 ± 0.416
1.93ValTyr: 1.93 ± 4.786
0.0ValXaa: 0.0 ± 0.0
Trp
0.965TrpAla: 0.965 ± 2.393
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.482TrpPhe: 0.482 ± 0.208
0.482TrpGly: 0.482 ± 2.601
0.0TrpHis: 0.0 ± 0.0
0.965TrpIle: 0.965 ± 0.416
1.447TrpLys: 1.447 ± 0.624
0.482TrpLeu: 0.482 ± 0.208
0.482TrpMet: 0.482 ± 0.208
0.482TrpAsn: 0.482 ± 2.601
0.0TrpPro: 0.0 ± 0.0
0.482TrpGln: 0.482 ± 2.601
0.482TrpArg: 0.482 ± 0.208
0.965TrpSer: 0.965 ± 2.393
0.0TrpThr: 0.0 ± 0.0
0.482TrpVal: 0.482 ± 0.208
0.0TrpTrp: 0.0 ± 0.0
0.482TrpTyr: 0.482 ± 2.601
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.93TyrAla: 1.93 ± 0.832
0.965TyrCys: 0.965 ± 0.416
4.342TyrAsp: 4.342 ± 0.937
2.412TyrGlu: 2.412 ± 1.04
2.412TyrPhe: 2.412 ± 1.04
1.447TyrGly: 1.447 ± 0.624
1.447TyrHis: 1.447 ± 0.624
1.447TyrIle: 1.447 ± 0.624
2.894TyrLys: 2.894 ± 1.561
2.412TyrLeu: 2.412 ± 1.04
0.0TyrMet: 0.0 ± 0.0
0.482TyrAsn: 0.482 ± 0.208
1.93TyrPro: 1.93 ± 0.832
2.412TyrGln: 2.412 ± 1.04
1.447TyrArg: 1.447 ± 0.624
2.894TyrSer: 2.894 ± 1.561
1.93TyrThr: 1.93 ± 1.977
2.894TyrVal: 2.894 ± 1.561
0.0TyrTrp: 0.0 ± 0.0
1.447TyrTyr: 1.447 ± 0.624
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2074 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski