Amino acid dipepetide frequency for Steccherinum ochraceum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.042AlaAla: 9.042 ± 0.058	1.027AlaCys: 1.027 ± 0.013	4.442AlaAsp: 4.442 ± 0.031	5.005AlaGlu: 5.005 ± 0.033	3.432AlaPhe: 3.432 ± 0.024	5.525AlaGly: 5.525 ± 0.039	2.116AlaHis: 2.116 ± 0.019	4.089AlaIle: 4.089 ± 0.031	3.915AlaLys: 3.915 ± 0.032	8.456AlaLeu: 8.456 ± 0.039	1.984AlaMet: 1.984 ± 0.021	2.785AlaAsn: 2.785 ± 0.025	5.565AlaPro: 5.565 ± 0.045	3.472AlaGln: 3.472 ± 0.027	5.19AlaArg: 5.19 ± 0.034	7.999AlaSer: 7.999 ± 0.05	5.355AlaThr: 5.355 ± 0.032	5.84AlaVal: 5.84 ± 0.031	1.146AlaTrp: 1.146 ± 0.016	2.223AlaTyr: 2.223 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	0.921CysAla: 0.921 ± 0.013	0.201CysCys: 0.201 ± 0.006	0.598CysAsp: 0.598 ± 0.011	0.535CysGlu: 0.535 ± 0.01	0.471CysPhe: 0.471 ± 0.009	0.81CysGly: 0.81 ± 0.012	0.307CysHis: 0.307 ± 0.006	0.614CysIle: 0.614 ± 0.011	0.497CysLys: 0.497 ± 0.009	1.163CysLeu: 1.163 ± 0.014	0.265CysMet: 0.265 ± 0.007	0.363CysAsn: 0.363 ± 0.008	0.638CysPro: 0.638 ± 0.009	0.394CysGln: 0.394 ± 0.009	0.694CysArg: 0.694 ± 0.011	0.885CysSer: 0.885 ± 0.014	0.701CysThr: 0.701 ± 0.011	0.753CysVal: 0.753 ± 0.012	0.19CysTrp: 0.19 ± 0.005	0.315CysTyr: 0.315 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.228AspAla: 5.228 ± 0.027	0.58AspCys: 0.58 ± 0.011	4.564AspAsp: 4.564 ± 0.043	4.5AspGlu: 4.5 ± 0.033	2.171AspPhe: 2.171 ± 0.019	3.958AspGly: 3.958 ± 0.026	1.33AspHis: 1.33 ± 0.015	2.998AspIle: 2.998 ± 0.023	2.087AspLys: 2.087 ± 0.02	5.256AspLeu: 5.256 ± 0.034	1.301AspMet: 1.301 ± 0.016	1.604AspAsn: 1.604 ± 0.017	3.609AspPro: 3.609 ± 0.029	1.654AspGln: 1.654 ± 0.015	2.896AspArg: 2.896 ± 0.026	4.151AspSer: 4.151 ± 0.032	3.101AspThr: 3.101 ± 0.022	4.431AspVal: 4.431 ± 0.03	0.915AspTrp: 0.915 ± 0.013	1.442AspTyr: 1.442 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.008GluAla: 5.008 ± 0.031	0.586GluCys: 0.586 ± 0.01	4.542GluAsp: 4.542 ± 0.037	5.377GluGlu: 5.377 ± 0.052	1.84GluPhe: 1.84 ± 0.021	3.534GluGly: 3.534 ± 0.025	1.502GluHis: 1.502 ± 0.017	2.692GluIle: 2.692 ± 0.024	3.092GluLys: 3.092 ± 0.027	5.318GluLeu: 5.318 ± 0.034	1.359GluMet: 1.359 ± 0.015	1.781GluAsn: 1.781 ± 0.019	2.714GluPro: 2.714 ± 0.025	2.185GluGln: 2.185 ± 0.019	3.804GluArg: 3.804 ± 0.036	3.926GluSer: 3.926 ± 0.03	3.015GluThr: 3.015 ± 0.024	3.879GluVal: 3.879 ± 0.032	0.897GluTrp: 0.897 ± 0.012	1.531GluTyr: 1.531 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.293PheAla: 3.293 ± 0.025	0.511PheCys: 0.511 ± 0.01	2.295PheAsp: 2.295 ± 0.021	1.936PheGlu: 1.936 ± 0.023	1.542PhePhe: 1.542 ± 0.02	2.723PheGly: 2.723 ± 0.027	0.944PheHis: 0.944 ± 0.013	1.795PheIle: 1.795 ± 0.02	1.558PheLys: 1.558 ± 0.018	3.494PheLeu: 3.494 ± 0.026	0.801PheMet: 0.801 ± 0.012	1.305PheAsn: 1.305 ± 0.016	2.141PhePro: 2.141 ± 0.02	1.231PheGln: 1.231 ± 0.016	2.032PheArg: 2.032 ± 0.018	3.08PheSer: 3.08 ± 0.023	2.298PheThr: 2.298 ± 0.025	2.625PheVal: 2.625 ± 0.024	0.574PheTrp: 0.574 ± 0.011	1.035PheTyr: 1.035 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	4.962GlyAla: 4.962 ± 0.036	0.753GlyCys: 0.753 ± 0.012	3.426GlyAsp: 3.426 ± 0.025	3.376GlyGlu: 3.376 ± 0.026	2.53GlyPhe: 2.53 ± 0.025	5.371GlyGly: 5.371 ± 0.047	1.66GlyHis: 1.66 ± 0.02	3.008GlyIle: 3.008 ± 0.025	3.096GlyLys: 3.096 ± 0.03	5.616GlyLeu: 5.616 ± 0.029	1.459GlyMet: 1.459 ± 0.018	2.112GlyAsn: 2.112 ± 0.022	3.464GlyPro: 3.464 ± 0.026	2.249GlyGln: 2.249 ± 0.023	3.859GlyArg: 3.859 ± 0.03	5.648GlySer: 5.648 ± 0.039	3.776GlyThr: 3.776 ± 0.033	4.247GlyVal: 4.247 ± 0.034	1.048GlyTrp: 1.048 ± 0.013	1.803GlyTyr: 1.803 ± 0.02	0.0GlyXaa: 0.0 ± 0.0
His	2.228HisAla: 2.228 ± 0.021	0.326HisCys: 0.326 ± 0.008	1.427HisAsp: 1.427 ± 0.017	1.266HisGlu: 1.266 ± 0.013	1.013HisPhe: 1.013 ± 0.013	1.638HisGly: 1.638 ± 0.02	0.902HisHis: 0.902 ± 0.02	1.368HisIle: 1.368 ± 0.016	0.89HisLys: 0.89 ± 0.013	2.691HisLeu: 2.691 ± 0.024	0.5HisMet: 0.5 ± 0.01	0.802HisAsn: 0.802 ± 0.012	1.986HisPro: 1.986 ± 0.018	0.864HisGln: 0.864 ± 0.012	1.629HisArg: 1.629 ± 0.018	2.105HisSer: 2.105 ± 0.022	1.479HisThr: 1.479 ± 0.016	1.742HisVal: 1.742 ± 0.017	0.362HisTrp: 0.362 ± 0.009	0.687HisTyr: 0.687 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.103IleAla: 4.103 ± 0.03	0.643IleCys: 0.643 ± 0.01	2.567IleAsp: 2.567 ± 0.021	2.426IleGlu: 2.426 ± 0.02	1.828IlePhe: 1.828 ± 0.018	2.778IleGly: 2.778 ± 0.025	1.227IleHis: 1.227 ± 0.014	2.186IleIle: 2.186 ± 0.022	1.824IleLys: 1.824 ± 0.021	4.583IleLeu: 4.583 ± 0.034	0.922IleMet: 0.922 ± 0.012	1.431IleAsn: 1.431 ± 0.018	3.369IlePro: 3.369 ± 0.028	1.721IleGln: 1.721 ± 0.017	2.795IleArg: 2.795 ± 0.024	3.701IleSer: 3.701 ± 0.022	2.723IleThr: 2.723 ± 0.022	3.265IleVal: 3.265 ± 0.024	0.703IleTrp: 0.703 ± 0.012	1.222IleTyr: 1.222 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.154LysAla: 4.154 ± 0.036	0.407LysCys: 0.407 ± 0.009	2.527LysAsp: 2.527 ± 0.022	3.014LysGlu: 3.014 ± 0.028	1.389LysPhe: 1.389 ± 0.017	2.648LysGly: 2.648 ± 0.024	1.119LysHis: 1.119 ± 0.014	1.941LysIle: 1.941 ± 0.02	2.876LysLys: 2.876 ± 0.036	3.906LysLeu: 3.906 ± 0.033	0.908LysMet: 0.908 ± 0.013	1.37LysAsn: 1.37 ± 0.016	2.579LysPro: 2.579 ± 0.027	1.62LysGln: 1.62 ± 0.017	3.296LysArg: 3.296 ± 0.027	3.082LysSer: 3.082 ± 0.03	2.584LysThr: 2.584 ± 0.024	2.672LysVal: 2.672 ± 0.024	0.649LysTrp: 0.649 ± 0.011	1.217LysTyr: 1.217 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	8.189LeuAla: 8.189 ± 0.043	1.203LeuCys: 1.203 ± 0.015	5.384LeuAsp: 5.384 ± 0.033	5.45LeuGlu: 5.45 ± 0.045	3.417LeuPhe: 3.417 ± 0.026	5.483LeuGly: 5.483 ± 0.034	2.603LeuHis: 2.603 ± 0.023	3.752LeuIle: 3.752 ± 0.026	4.167LeuLys: 4.167 ± 0.031	8.685LeuLeu: 8.685 ± 0.047	1.711LeuMet: 1.711 ± 0.017	3.03LeuAsn: 3.03 ± 0.023	6.467LeuPro: 6.467 ± 0.039	3.912LeuGln: 3.912 ± 0.03	6.236LeuArg: 6.236 ± 0.039	8.154LeuSer: 8.154 ± 0.043	5.336LeuThr: 5.336 ± 0.038	5.877LeuVal: 5.877 ± 0.035	1.207LeuTrp: 1.207 ± 0.016	2.416LeuTyr: 2.416 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.954MetAla: 1.954 ± 0.017	0.22MetCys: 0.22 ± 0.006	1.288MetAsp: 1.288 ± 0.016	1.159MetGlu: 1.159 ± 0.015	0.808MetPhe: 0.808 ± 0.013	1.224MetGly: 1.224 ± 0.017	0.535MetHis: 0.535 ± 0.01	0.895MetIle: 0.895 ± 0.012	0.956MetLys: 0.956 ± 0.013	1.858MetLeu: 1.858 ± 0.02	0.529MetMet: 0.529 ± 0.01	0.754MetAsn: 0.754 ± 0.011	1.285MetPro: 1.285 ± 0.015	0.872MetGln: 0.872 ± 0.013	1.325MetArg: 1.325 ± 0.015	2.032MetSer: 2.032 ± 0.022	1.23MetThr: 1.23 ± 0.016	1.218MetVal: 1.218 ± 0.014	0.276MetTrp: 0.276 ± 0.007	0.531MetTyr: 0.531 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.191AsnAla: 3.191 ± 0.027	0.342AsnCys: 0.342 ± 0.007	1.728AsnAsp: 1.728 ± 0.019	1.619AsnGlu: 1.619 ± 0.017	1.223AsnPhe: 1.223 ± 0.016	2.596AsnGly: 2.596 ± 0.026	0.773AsnHis: 0.773 ± 0.011	1.737AsnIle: 1.737 ± 0.018	1.184AsnLys: 1.184 ± 0.015	3.064AsnLeu: 3.064 ± 0.023	0.716AsnMet: 0.716 ± 0.012	1.133AsnAsn: 1.133 ± 0.018	2.275AsnPro: 2.275 ± 0.021	1.01AsnGln: 1.01 ± 0.015	1.615AsnArg: 1.615 ± 0.018	2.338AsnSer: 2.338 ± 0.022	2.013AsnThr: 2.013 ± 0.021	2.438AsnVal: 2.438 ± 0.02	0.449AsnTrp: 0.449 ± 0.01	0.824AsnTyr: 0.824 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	5.98ProAla: 5.98 ± 0.039	0.483ProCys: 0.483 ± 0.01	3.344ProAsp: 3.344 ± 0.024	3.831ProGlu: 3.831 ± 0.027	2.251ProPhe: 2.251 ± 0.024	3.81ProGly: 3.81 ± 0.03	1.698ProHis: 1.698 ± 0.02	2.691ProIle: 2.691 ± 0.024	2.505ProLys: 2.505 ± 0.026	5.47ProLeu: 5.47 ± 0.033	1.107ProMet: 1.107 ± 0.014	2.217ProAsn: 2.217 ± 0.022	7.069ProPro: 7.069 ± 0.074	2.574ProGln: 2.574 ± 0.026	3.678ProArg: 3.678 ± 0.029	7.684ProSer: 7.684 ± 0.051	4.752ProThr: 4.752 ± 0.035	4.066ProVal: 4.066 ± 0.03	0.716ProTrp: 0.716 ± 0.011	1.578ProTyr: 1.578 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.466GlnAla: 3.466 ± 0.028	0.433GlnCys: 0.433 ± 0.009	2.127GlnAsp: 2.127 ± 0.018	2.14GlnGlu: 2.14 ± 0.021	1.279GlnPhe: 1.279 ± 0.016	2.036GlnGly: 2.036 ± 0.019	1.087GlnHis: 1.087 ± 0.014	1.686GlnIle: 1.686 ± 0.018	1.581GlnLys: 1.581 ± 0.018	3.415GlnLeu: 3.415 ± 0.021	0.792GlnMet: 0.792 ± 0.011	1.255GlnAsn: 1.255 ± 0.016	2.525GlnPro: 2.525 ± 0.027	1.97GlnGln: 1.97 ± 0.037	2.451GlnArg: 2.451 ± 0.019	3.085GlnSer: 3.085 ± 0.031	2.234GlnThr: 2.234 ± 0.022	2.21GlnVal: 2.21 ± 0.019	0.562GlnTrp: 0.562 ± 0.01	1.096GlnTyr: 1.096 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	5.035ArgAla: 5.035 ± 0.031	0.697ArgCys: 0.697 ± 0.012	3.383ArgAsp: 3.383 ± 0.03	3.702ArgGlu: 3.702 ± 0.028	2.158ArgPhe: 2.158 ± 0.019	3.484ArgGly: 3.484 ± 0.03	1.591ArgHis: 1.591 ± 0.017	2.886ArgIle: 2.886 ± 0.023	3.224ArgLys: 3.224 ± 0.027	5.614ArgLeu: 5.614 ± 0.034	1.386ArgMet: 1.386 ± 0.014	1.993ArgAsn: 1.993 ± 0.019	3.743ArgPro: 3.743 ± 0.031	2.262ArgGln: 2.262 ± 0.022	5.136ArgArg: 5.136 ± 0.036	5.255ArgSer: 5.255 ± 0.033	3.648ArgThr: 3.648 ± 0.029	3.699ArgVal: 3.699 ± 0.026	0.94ArgTrp: 0.94 ± 0.013	1.652ArgTyr: 1.652 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	7.323SerAla: 7.323 ± 0.047	0.836SerCys: 0.836 ± 0.015	4.58SerAsp: 4.58 ± 0.03	4.159SerGlu: 4.159 ± 0.028	3.159SerPhe: 3.159 ± 0.025	5.567SerGly: 5.567 ± 0.039	2.181SerHis: 2.181 ± 0.021	3.751SerIle: 3.751 ± 0.028	3.395SerLys: 3.395 ± 0.026	7.984SerLeu: 7.984 ± 0.041	1.743SerMet: 1.743 ± 0.02	2.73SerAsn: 2.73 ± 0.024	6.708SerPro: 6.708 ± 0.059	3.375SerGln: 3.375 ± 0.027	5.235SerArg: 5.235 ± 0.035	10.65SerSer: 10.65 ± 0.084	6.153SerThr: 6.153 ± 0.04	5.225SerVal: 5.225 ± 0.033	1.079SerTrp: 1.079 ± 0.015	1.992SerTyr: 1.992 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.373ThrAla: 5.373 ± 0.03	0.695ThrCys: 0.695 ± 0.011	2.85ThrAsp: 2.85 ± 0.024	2.854ThrGlu: 2.854 ± 0.021	2.455ThrPhe: 2.455 ± 0.021	3.759ThrGly: 3.759 ± 0.026	1.543ThrHis: 1.543 ± 0.017	2.935ThrIle: 2.935 ± 0.023	2.304ThrLys: 2.304 ± 0.022	5.939ThrLeu: 5.939 ± 0.033	1.195ThrMet: 1.195 ± 0.014	1.926ThrAsn: 1.926 ± 0.019	4.896ThrPro: 4.896 ± 0.042	2.102ThrGln: 2.102 ± 0.018	3.398ThrArg: 3.398 ± 0.024	5.984ThrSer: 5.984 ± 0.042	4.279ThrThr: 4.279 ± 0.035	4.043ThrVal: 4.043 ± 0.027	0.82ThrTrp: 0.82 ± 0.013	1.576ThrTyr: 1.576 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	5.842ValAla: 5.842 ± 0.037	0.821ValCys: 0.821 ± 0.012	4.127ValAsp: 4.127 ± 0.027	4.002ValGlu: 4.002 ± 0.029	2.605ValPhe: 2.605 ± 0.022	3.875ValGly: 3.875 ± 0.031	1.696ValHis: 1.696 ± 0.017	2.982ValIle: 2.982 ± 0.025	3.019ValLys: 3.019 ± 0.027	6.375ValLeu: 6.375 ± 0.037	1.362ValMet: 1.362 ± 0.016	2.148ValAsn: 2.148 ± 0.02	4.269ValPro: 4.269 ± 0.029	2.534ValGln: 2.534 ± 0.021	3.664ValArg: 3.664 ± 0.022	5.002ValSer: 5.002 ± 0.03	3.746ValThr: 3.746 ± 0.026	4.955ValVal: 4.955 ± 0.035	0.937ValTrp: 0.937 ± 0.014	1.814ValTyr: 1.814 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.044TrpAla: 1.044 ± 0.013	0.179TrpCys: 0.179 ± 0.006	0.92TrpAsp: 0.92 ± 0.014	0.834TrpGlu: 0.834 ± 0.012	0.553TrpPhe: 0.553 ± 0.01	0.818TrpGly: 0.818 ± 0.013	0.358TrpHis: 0.358 ± 0.008	0.735TrpIle: 0.735 ± 0.012	0.78TrpLys: 0.78 ± 0.011	1.269TrpLeu: 1.269 ± 0.014	0.362TrpMet: 0.362 ± 0.007	0.586TrpAsn: 0.586 ± 0.011	0.621TrpPro: 0.621 ± 0.011	0.51TrpGln: 0.51 ± 0.009	1.013TrpArg: 1.013 ± 0.013	1.108TrpSer: 1.108 ± 0.015	0.915TrpThr: 0.915 ± 0.015	0.877TrpVal: 0.877 ± 0.013	0.27TrpTrp: 0.27 ± 0.007	0.404TrpTyr: 0.404 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.273TyrAla: 2.273 ± 0.018	0.374TyrCys: 0.374 ± 0.008	1.655TyrAsp: 1.655 ± 0.018	1.396TyrGlu: 1.396 ± 0.015	1.089TyrPhe: 1.089 ± 0.014	1.824TyrGly: 1.824 ± 0.02	0.734TyrHis: 0.734 ± 0.012	1.274TyrIle: 1.274 ± 0.017	1.009TyrLys: 1.009 ± 0.014	2.523TyrLeu: 2.523 ± 0.023	0.548TyrMet: 0.548 ± 0.01	0.945TyrAsn: 0.945 ± 0.014	1.578TyrPro: 1.578 ± 0.023	0.919TyrGln: 0.919 ± 0.015	1.545TyrArg: 1.545 ± 0.017	1.955TyrSer: 1.955 ± 0.02	1.588TyrThr: 1.588 ± 0.017	1.71TyrVal: 1.71 ± 0.015	0.418TyrTrp: 0.418 ± 0.009	0.805TyrTyr: 0.805 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12246 proteins (5899370 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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