Amino acid dipepetide frequency for Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.074AlaAla: 6.074 ± 0.095	0.933AlaCys: 0.933 ± 0.022	3.47AlaAsp: 3.47 ± 0.039	4.474AlaGlu: 4.474 ± 0.054	2.835AlaPhe: 2.835 ± 0.038	3.808AlaGly: 3.808 ± 0.05	1.682AlaHis: 1.682 ± 0.027	3.641AlaIle: 3.641 ± 0.049	4.496AlaLys: 4.496 ± 0.05	6.532AlaLeu: 6.532 ± 0.06	1.454AlaMet: 1.454 ± 0.025	3.054AlaAsn: 3.054 ± 0.04	3.654AlaPro: 3.654 ± 0.074	3.025AlaGln: 3.025 ± 0.035	3.821AlaArg: 3.821 ± 0.052	6.793AlaSer: 6.793 ± 0.067	3.894AlaThr: 3.894 ± 0.051	4.463AlaVal: 4.463 ± 0.045	0.664AlaTrp: 0.664 ± 0.019	1.912AlaTyr: 1.912 ± 0.028	0.0AlaXaa: 0.0 ± 0.0
Cys	0.872CysAla: 0.872 ± 0.019	0.277CysCys: 0.277 ± 0.011	0.692CysAsp: 0.692 ± 0.016	0.603CysGlu: 0.603 ± 0.014	0.72CysPhe: 0.72 ± 0.017	0.943CysGly: 0.943 ± 0.021	0.333CysHis: 0.333 ± 0.014	0.797CysIle: 0.797 ± 0.018	0.624CysLys: 0.624 ± 0.013	1.317CysLeu: 1.317 ± 0.024	0.278CysMet: 0.278 ± 0.01	0.529CysAsn: 0.529 ± 0.014	0.569CysPro: 0.569 ± 0.017	0.4CysGln: 0.4 ± 0.015	0.628CysArg: 0.628 ± 0.017	1.162CysSer: 1.162 ± 0.027	0.694CysThr: 0.694 ± 0.022	0.884CysVal: 0.884 ± 0.019	0.18CysTrp: 0.18 ± 0.009	0.429CysTyr: 0.429 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	3.822AspAla: 3.822 ± 0.043	0.627AspCys: 0.627 ± 0.019	4.013AspAsp: 4.013 ± 0.062	4.528AspGlu: 4.528 ± 0.057	2.772AspPhe: 2.772 ± 0.03	2.973AspGly: 2.973 ± 0.04	1.202AspHis: 1.202 ± 0.022	3.298AspIle: 3.298 ± 0.035	3.073AspLys: 3.073 ± 0.039	5.472AspLeu: 5.472 ± 0.051	1.243AspMet: 1.243 ± 0.023	2.36AspAsn: 2.36 ± 0.028	2.564AspPro: 2.564 ± 0.031	1.709AspGln: 1.709 ± 0.026	2.233AspArg: 2.233 ± 0.031	5.076AspSer: 5.076 ± 0.055	2.861AspThr: 2.861 ± 0.035	3.795AspVal: 3.795 ± 0.04	0.61AspTrp: 0.61 ± 0.017	1.969AspTyr: 1.969 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	4.479GluAla: 4.479 ± 0.051	0.666GluCys: 0.666 ± 0.019	4.132GluAsp: 4.132 ± 0.056	6.06GluGlu: 6.06 ± 0.094	2.487GluPhe: 2.487 ± 0.029	2.828GluGly: 2.828 ± 0.039	1.44GluHis: 1.44 ± 0.026	3.653GluIle: 3.653 ± 0.044	5.424GluLys: 5.424 ± 0.064	5.867GluLeu: 5.867 ± 0.058	1.388GluMet: 1.388 ± 0.023	3.666GluAsn: 3.666 ± 0.045	2.376GluPro: 2.376 ± 0.039	2.591GluGln: 2.591 ± 0.034	3.234GluArg: 3.234 ± 0.045	5.506GluSer: 5.506 ± 0.06	3.755GluThr: 3.755 ± 0.053	3.731GluVal: 3.731 ± 0.047	0.662GluTrp: 0.662 ± 0.016	2.054GluTyr: 2.054 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.026PheAla: 3.026 ± 0.037	0.681PheCys: 0.681 ± 0.017	2.661PheAsp: 2.661 ± 0.034	2.685PheGlu: 2.685 ± 0.037	2.319PhePhe: 2.319 ± 0.035	2.972PheGly: 2.972 ± 0.055	1.094PheHis: 1.094 ± 0.02	2.286PheIle: 2.286 ± 0.035	2.424PheLys: 2.424 ± 0.034	4.237PheLeu: 4.237 ± 0.043	0.919PheMet: 0.919 ± 0.019	2.138PheAsn: 2.138 ± 0.031	1.924PhePro: 1.924 ± 0.028	1.628PheGln: 1.628 ± 0.026	2.005PheArg: 2.005 ± 0.03	4.311PheSer: 4.311 ± 0.052	2.276PheThr: 2.276 ± 0.035	3.08PheVal: 3.08 ± 0.037	0.586PheTrp: 0.586 ± 0.015	1.422PheTyr: 1.422 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	4.04GlyAla: 4.04 ± 0.057	0.78GlyCys: 0.78 ± 0.022	2.988GlyAsp: 2.988 ± 0.043	3.147GlyGlu: 3.147 ± 0.044	2.598GlyPhe: 2.598 ± 0.035	3.699GlyGly: 3.699 ± 0.066	1.394GlyHis: 1.394 ± 0.026	3.0GlyIle: 3.0 ± 0.038	3.46GlyLys: 3.46 ± 0.035	4.82GlyLeu: 4.82 ± 0.05	1.066GlyMet: 1.066 ± 0.023	2.544GlyAsn: 2.544 ± 0.031	2.194GlyPro: 2.194 ± 0.036	1.95GlyGln: 1.95 ± 0.029	2.767GlyArg: 2.767 ± 0.043	5.284GlySer: 5.284 ± 0.102	3.085GlyThr: 3.085 ± 0.051	3.761GlyVal: 3.761 ± 0.048	0.652GlyTrp: 0.652 ± 0.017	1.803GlyTyr: 1.803 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	1.488HisAla: 1.488 ± 0.025	0.329HisCys: 0.329 ± 0.012	1.233HisAsp: 1.233 ± 0.023	1.472HisGlu: 1.472 ± 0.028	1.172HisPhe: 1.172 ± 0.021	1.408HisGly: 1.408 ± 0.025	0.799HisHis: 0.799 ± 0.026	1.335HisIle: 1.335 ± 0.023	1.356HisLys: 1.356 ± 0.024	2.354HisLeu: 2.354 ± 0.031	0.513HisMet: 0.513 ± 0.014	1.078HisAsn: 1.078 ± 0.019	1.202HisPro: 1.202 ± 0.023	1.011HisGln: 1.011 ± 0.025	1.228HisArg: 1.228 ± 0.026	2.165HisSer: 2.165 ± 0.036	1.234HisThr: 1.234 ± 0.022	1.638HisVal: 1.638 ± 0.027	0.273HisTrp: 0.273 ± 0.01	0.817HisTyr: 0.817 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	3.571IleAla: 3.571 ± 0.037	0.772IleCys: 0.772 ± 0.02	3.304IleAsp: 3.304 ± 0.037	3.415IleGlu: 3.415 ± 0.039	2.43IlePhe: 2.43 ± 0.035	2.79IleGly: 2.79 ± 0.04	1.268IleHis: 1.268 ± 0.019	2.813IleIle: 2.813 ± 0.042	3.122IleLys: 3.122 ± 0.042	4.946IleLeu: 4.946 ± 0.057	1.09IleMet: 1.09 ± 0.02	2.511IleAsn: 2.511 ± 0.032	2.692IlePro: 2.692 ± 0.035	1.895IleGln: 1.895 ± 0.027	2.562IleArg: 2.562 ± 0.029	4.93IleSer: 4.93 ± 0.056	2.897IleThr: 2.897 ± 0.033	3.61IleVal: 3.61 ± 0.042	0.573IleTrp: 0.573 ± 0.015	1.675IleTyr: 1.675 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	4.057LysAla: 4.057 ± 0.055	0.699LysCys: 0.699 ± 0.017	3.479LysAsp: 3.479 ± 0.039	4.635LysGlu: 4.635 ± 0.059	2.544LysPhe: 2.544 ± 0.034	2.709LysGly: 2.709 ± 0.031	1.507LysHis: 1.507 ± 0.024	3.492LysIle: 3.492 ± 0.039	5.332LysLys: 5.332 ± 0.078	5.922LysLeu: 5.922 ± 0.055	1.34LysMet: 1.34 ± 0.026	3.118LysAsn: 3.118 ± 0.042	2.894LysPro: 2.894 ± 0.044	2.483LysGln: 2.483 ± 0.031	3.576LysArg: 3.576 ± 0.045	5.268LysSer: 5.268 ± 0.057	3.514LysThr: 3.514 ± 0.041	3.83LysVal: 3.83 ± 0.04	0.701LysTrp: 0.701 ± 0.017	2.238LysTyr: 2.238 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	7.051LeuAla: 7.051 ± 0.058	1.333LeuCys: 1.333 ± 0.024	5.197LeuAsp: 5.197 ± 0.051	5.771LeuGlu: 5.771 ± 0.059	4.001LeuPhe: 4.001 ± 0.041	5.093LeuGly: 5.093 ± 0.051	2.302LeuHis: 2.302 ± 0.028	4.543LeuIle: 4.543 ± 0.055	5.713LeuLys: 5.713 ± 0.052	8.884LeuLeu: 8.884 ± 0.086	1.847LeuMet: 1.847 ± 0.028	4.254LeuAsn: 4.254 ± 0.042	4.443LeuPro: 4.443 ± 0.052	3.866LeuGln: 3.866 ± 0.045	4.933LeuArg: 4.933 ± 0.046	8.835LeuSer: 8.835 ± 0.073	4.661LeuThr: 4.661 ± 0.047	6.31LeuVal: 6.31 ± 0.06	0.962LeuTrp: 0.962 ± 0.02	2.711LeuTyr: 2.711 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	1.711MetAla: 1.711 ± 0.028	0.29MetCys: 0.29 ± 0.01	1.241MetAsp: 1.241 ± 0.022	1.273MetGlu: 1.273 ± 0.023	0.88MetPhe: 0.88 ± 0.018	1.174MetGly: 1.174 ± 0.024	0.419MetHis: 0.419 ± 0.013	1.009MetIle: 1.009 ± 0.018	1.344MetLys: 1.344 ± 0.025	1.759MetLeu: 1.759 ± 0.028	0.512MetMet: 0.512 ± 0.015	0.978MetAsn: 0.978 ± 0.024	0.954MetPro: 0.954 ± 0.024	0.711MetGln: 0.711 ± 0.016	1.06MetArg: 1.06 ± 0.02	2.213MetSer: 2.213 ± 0.033	1.031MetThr: 1.031 ± 0.019	1.31MetVal: 1.31 ± 0.025	0.209MetTrp: 0.209 ± 0.01	0.647MetTyr: 0.647 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.048AsnAla: 3.048 ± 0.036	0.54AsnCys: 0.54 ± 0.013	2.708AsnAsp: 2.708 ± 0.037	3.095AsnGlu: 3.095 ± 0.035	2.162AsnPhe: 2.162 ± 0.031	2.962AsnGly: 2.962 ± 0.04	1.125AsnHis: 1.125 ± 0.019	2.691AsnIle: 2.691 ± 0.032	2.69AsnLys: 2.69 ± 0.033	4.263AsnLeu: 4.263 ± 0.047	1.031AsnMet: 1.031 ± 0.02	2.338AsnAsn: 2.338 ± 0.05	2.257AsnPro: 2.257 ± 0.03	1.742AsnGln: 1.742 ± 0.034	1.926AsnArg: 1.926 ± 0.029	4.229AsnSer: 4.229 ± 0.051	2.561AsnThr: 2.561 ± 0.036	3.147AsnVal: 3.147 ± 0.037	0.545AsnTrp: 0.545 ± 0.016	1.661AsnTyr: 1.661 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	3.321ProAla: 3.321 ± 0.051	0.442ProCys: 0.442 ± 0.013	2.424ProAsp: 2.424 ± 0.03	3.537ProGlu: 3.537 ± 0.038	1.988ProPhe: 1.988 ± 0.03	2.434ProGly: 2.434 ± 0.057	1.194ProHis: 1.194 ± 0.025	2.292ProIle: 2.292 ± 0.03	2.947ProLys: 2.947 ± 0.042	4.005ProLeu: 4.005 ± 0.039	0.879ProMet: 0.879 ± 0.019	2.124ProAsn: 2.124 ± 0.034	2.978ProPro: 2.978 ± 0.084	2.258ProGln: 2.258 ± 0.038	2.227ProArg: 2.227 ± 0.047	4.846ProSer: 4.846 ± 0.076	2.721ProThr: 2.721 ± 0.045	3.208ProVal: 3.208 ± 0.041	0.453ProTrp: 0.453 ± 0.015	1.362ProTyr: 1.362 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	2.59GlnAla: 2.59 ± 0.037	0.433GlnCys: 0.433 ± 0.014	1.857GlnAsp: 1.857 ± 0.032	2.576GlnGlu: 2.576 ± 0.034	1.598GlnPhe: 1.598 ± 0.027	1.812GlnGly: 1.812 ± 0.029	0.957GlnHis: 0.957 ± 0.023	2.089GlnIle: 2.089 ± 0.029	2.695GlnLys: 2.695 ± 0.032	3.807GlnLeu: 3.807 ± 0.044	0.945GlnMet: 0.945 ± 0.025	2.022GlnAsn: 2.022 ± 0.033	1.783GlnPro: 1.783 ± 0.037	2.33GlnGln: 2.33 ± 0.08	2.069GlnArg: 2.069 ± 0.036	3.233GlnSer: 3.233 ± 0.047	2.161GlnThr: 2.161 ± 0.034	2.396GlnVal: 2.396 ± 0.033	0.418GlnTrp: 0.418 ± 0.012	1.263GlnTyr: 1.263 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	3.559ArgAla: 3.559 ± 0.05	0.665ArgCys: 0.665 ± 0.017	2.499ArgAsp: 2.499 ± 0.032	3.052ArgGlu: 3.052 ± 0.044	2.285ArgPhe: 2.285 ± 0.032	2.474ArgGly: 2.474 ± 0.033	1.341ArgHis: 1.341 ± 0.027	2.629ArgIle: 2.629 ± 0.032	3.567ArgLys: 3.567 ± 0.044	4.837ArgLeu: 4.837 ± 0.056	1.081ArgMet: 1.081 ± 0.024	2.364ArgAsn: 2.364 ± 0.033	2.234ArgPro: 2.234 ± 0.041	2.058ArgGln: 2.058 ± 0.034	3.676ArgArg: 3.676 ± 0.069	4.368ArgSer: 4.368 ± 0.051	2.517ArgThr: 2.517 ± 0.032	2.963ArgVal: 2.963 ± 0.039	0.55ArgTrp: 0.55 ± 0.013	1.478ArgTyr: 1.478 ± 0.025	0.0ArgXaa: 0.0 ± 0.0
Ser	6.675SerAla: 6.675 ± 0.078	1.058SerCys: 1.058 ± 0.023	5.112SerAsp: 5.112 ± 0.055	5.665SerGlu: 5.665 ± 0.067	4.269SerPhe: 4.269 ± 0.051	5.464SerGly: 5.464 ± 0.075	2.255SerHis: 2.255 ± 0.035	4.799SerIle: 4.799 ± 0.055	5.582SerLys: 5.582 ± 0.061	8.614SerLeu: 8.614 ± 0.083	1.88SerMet: 1.88 ± 0.031	4.212SerAsn: 4.212 ± 0.05	4.716SerPro: 4.716 ± 0.082	3.542SerGln: 3.542 ± 0.045	4.589SerArg: 4.589 ± 0.047	11.434SerSer: 11.434 ± 0.234	5.762SerThr: 5.762 ± 0.081	6.022SerVal: 6.022 ± 0.066	0.97SerTrp: 0.97 ± 0.02	2.511SerTyr: 2.511 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	3.635ThrAla: 3.635 ± 0.049	0.729ThrCys: 0.729 ± 0.022	2.744ThrAsp: 2.744 ± 0.037	3.347ThrGlu: 3.347 ± 0.05	2.458ThrPhe: 2.458 ± 0.038	3.265ThrGly: 3.265 ± 0.055	1.218ThrHis: 1.218 ± 0.025	3.011ThrIle: 3.011 ± 0.039	3.394ThrLys: 3.394 ± 0.046	4.856ThrLeu: 4.856 ± 0.047	1.068ThrMet: 1.068 ± 0.019	2.607ThrAsn: 2.607 ± 0.036	3.074ThrPro: 3.074 ± 0.047	1.966ThrGln: 1.966 ± 0.028	2.543ThrArg: 2.543 ± 0.035	5.502ThrSer: 5.502 ± 0.087	3.471ThrThr: 3.471 ± 0.099	3.555ThrVal: 3.555 ± 0.06	0.588ThrTrp: 0.588 ± 0.017	1.643ThrTyr: 1.643 ± 0.027	0.0ThrXaa: 0.0 ± 0.0
Val	4.942ValAla: 4.942 ± 0.05	0.976ValCys: 0.976 ± 0.019	3.911ValAsp: 3.911 ± 0.039	4.158ValGlu: 4.158 ± 0.05	3.082ValPhe: 3.082 ± 0.036	3.723ValGly: 3.723 ± 0.049	1.563ValHis: 1.563 ± 0.028	3.172ValIle: 3.172 ± 0.041	3.543ValLys: 3.543 ± 0.041	6.086ValLeu: 6.086 ± 0.055	1.263ValMet: 1.263 ± 0.024	2.711ValAsn: 2.711 ± 0.039	3.398ValPro: 3.398 ± 0.052	2.34ValGln: 2.34 ± 0.032	3.09ValArg: 3.09 ± 0.04	6.372ValSer: 6.372 ± 0.068	3.377ValThr: 3.377 ± 0.051	4.862ValVal: 4.862 ± 0.07	0.744ValTrp: 0.744 ± 0.016	1.975ValTyr: 1.975 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	0.764TrpAla: 0.764 ± 0.018	0.231TrpCys: 0.231 ± 0.01	0.647TrpAsp: 0.647 ± 0.015	0.575TrpGlu: 0.575 ± 0.015	0.52TrpPhe: 0.52 ± 0.015	0.608TrpGly: 0.608 ± 0.018	0.243TrpHis: 0.243 ± 0.01	0.598TrpIle: 0.598 ± 0.017	0.741TrpLys: 0.741 ± 0.021	1.03TrpLeu: 1.03 ± 0.023	0.237TrpMet: 0.237 ± 0.009	0.585TrpAsn: 0.585 ± 0.014	0.401TrpPro: 0.401 ± 0.014	0.353TrpGln: 0.353 ± 0.011	0.661TrpArg: 0.661 ± 0.018	0.907TrpSer: 0.907 ± 0.019	0.567TrpThr: 0.567 ± 0.017	0.682TrpVal: 0.682 ± 0.017	0.187TrpTrp: 0.187 ± 0.01	0.368TrpTyr: 0.368 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.957TyrAla: 1.957 ± 0.028	0.47TyrCys: 0.47 ± 0.013	1.888TyrAsp: 1.888 ± 0.028	1.93TyrGlu: 1.93 ± 0.024	1.555TyrPhe: 1.555 ± 0.027	1.893TyrGly: 1.893 ± 0.036	0.769TyrHis: 0.769 ± 0.017	1.722TyrIle: 1.722 ± 0.031	1.808TyrLys: 1.808 ± 0.027	3.101TyrLeu: 3.101 ± 0.04	0.693TyrMet: 0.693 ± 0.016	1.526TyrAsn: 1.526 ± 0.025	1.334TyrPro: 1.334 ± 0.026	1.173TyrGln: 1.173 ± 0.022	1.369TyrArg: 1.369 ± 0.021	2.693TyrSer: 2.693 ± 0.035	1.636TyrThr: 1.636 ± 0.032	2.039TyrVal: 2.039 ± 0.028	0.381TyrTrp: 0.381 ± 0.012	1.216TyrTyr: 1.216 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5932 proteins (2742050 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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