Amino acid dipepetide frequency for Carlito syrichta (Philippine tarsier) (Tarsius syrichta)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.2AlaAla: 6.2 ± 0.037	1.367AlaCys: 1.367 ± 0.012	2.874AlaAsp: 2.874 ± 0.016	4.636AlaGlu: 4.636 ± 0.029	2.684AlaPhe: 2.684 ± 0.017	4.483AlaGly: 4.483 ± 0.027	1.527AlaHis: 1.527 ± 0.011	2.833AlaIle: 2.833 ± 0.015	3.446AlaLys: 3.446 ± 0.024	6.911AlaLeu: 6.911 ± 0.032	1.531AlaMet: 1.531 ± 0.01	1.999AlaAsn: 1.999 ± 0.009	3.898AlaPro: 3.898 ± 0.027	3.171AlaGln: 3.171 ± 0.021	3.559AlaArg: 3.559 ± 0.018	5.637AlaSer: 5.637 ± 0.027	3.59AlaThr: 3.59 ± 0.018	4.694AlaVal: 4.694 ± 0.021	0.777AlaTrp: 0.777 ± 0.009	1.529AlaTyr: 1.529 ± 0.012	0.01AlaXaa: 0.01 ± 0.001
Cys	1.206CysAla: 1.206 ± 0.011	0.663CysCys: 0.663 ± 0.013	1.009CysAsp: 1.009 ± 0.013	1.265CysGlu: 1.265 ± 0.013	0.838CysPhe: 0.838 ± 0.008	1.805CysGly: 1.805 ± 0.022	0.659CysHis: 0.659 ± 0.008	0.95CysIle: 0.95 ± 0.01	1.181CysLys: 1.181 ± 0.012	2.133CysLeu: 2.133 ± 0.016	0.422CysMet: 0.422 ± 0.005	0.836CysAsn: 0.836 ± 0.011	1.313CysPro: 1.313 ± 0.017	1.07CysGln: 1.07 ± 0.011	1.259CysArg: 1.259 ± 0.01	1.955CysSer: 1.955 ± 0.017	1.071CysThr: 1.071 ± 0.011	1.301CysVal: 1.301 ± 0.011	0.279CysTrp: 0.279 ± 0.005	0.578CysTyr: 0.578 ± 0.008	0.003CysXaa: 0.003 ± 0.0
Asp	2.859AspAla: 2.859 ± 0.017	1.044AspCys: 1.044 ± 0.011	2.679AspAsp: 2.679 ± 0.018	3.465AspGlu: 3.465 ± 0.023	2.145AspPhe: 2.145 ± 0.013	3.263AspGly: 3.263 ± 0.027	1.15AspHis: 1.15 ± 0.008	2.626AspIle: 2.626 ± 0.015	2.598AspLys: 2.598 ± 0.016	5.063AspLeu: 5.063 ± 0.024	1.128AspMet: 1.128 ± 0.009	1.702AspAsn: 1.702 ± 0.012	2.905AspPro: 2.905 ± 0.017	1.841AspGln: 1.841 ± 0.012	2.459AspArg: 2.459 ± 0.015	4.192AspSer: 4.192 ± 0.026	2.472AspThr: 2.472 ± 0.014	3.099AspVal: 3.099 ± 0.02	0.627AspTrp: 0.627 ± 0.007	1.454AspTyr: 1.454 ± 0.011	0.005AspXaa: 0.005 ± 0.001
Glu	5.113GluAla: 5.113 ± 0.031	1.566GluCys: 1.566 ± 0.024	4.449GluAsp: 4.449 ± 0.021	8.047GluGlu: 8.047 ± 0.045	2.084GluPhe: 2.084 ± 0.015	4.135GluGly: 4.135 ± 0.022	1.536GluHis: 1.536 ± 0.011	3.221GluIle: 3.221 ± 0.021	5.667GluLys: 5.667 ± 0.036	6.382GluLeu: 6.382 ± 0.036	1.727GluMet: 1.727 ± 0.014	3.172GluAsn: 3.172 ± 0.019	3.192GluPro: 3.192 ± 0.024	3.171GluGln: 3.171 ± 0.022	4.006GluArg: 4.006 ± 0.023	4.471GluSer: 4.471 ± 0.025	3.416GluThr: 3.416 ± 0.018	4.212GluVal: 4.212 ± 0.029	0.698GluTrp: 0.698 ± 0.007	1.651GluTyr: 1.651 ± 0.019	0.008GluXaa: 0.008 ± 0.001
Phe	1.993PheAla: 1.993 ± 0.014	0.95PheCys: 0.95 ± 0.009	1.724PheAsp: 1.724 ± 0.012	2.035PheGlu: 2.035 ± 0.011	1.626PhePhe: 1.626 ± 0.013	2.229PheGly: 2.229 ± 0.018	1.047PheHis: 1.047 ± 0.01	1.854PheIle: 1.854 ± 0.014	1.812PheLys: 1.812 ± 0.013	4.093PheLeu: 4.093 ± 0.026	0.793PheMet: 0.793 ± 0.008	1.356PheAsn: 1.356 ± 0.01	1.998PhePro: 1.998 ± 0.014	1.81PheGln: 1.81 ± 0.012	2.043PheArg: 2.043 ± 0.018	3.489PheSer: 3.489 ± 0.019	2.029PheThr: 2.029 ± 0.015	2.175PheVal: 2.175 ± 0.014	0.49PheTrp: 0.49 ± 0.007	1.177PheTyr: 1.177 ± 0.01	0.006PheXaa: 0.006 ± 0.001
Gly	4.193GlyAla: 4.193 ± 0.026	1.238GlyCys: 1.238 ± 0.012	3.101GlyAsp: 3.101 ± 0.02	4.213GlyGlu: 4.213 ± 0.029	2.436GlyPhe: 2.436 ± 0.019	4.715GlyGly: 4.715 ± 0.034	1.681GlyHis: 1.681 ± 0.014	2.783GlyIle: 2.783 ± 0.016	3.963GlyLys: 3.963 ± 0.026	5.83GlyLeu: 5.83 ± 0.031	1.341GlyMet: 1.341 ± 0.013	2.379GlyAsn: 2.379 ± 0.015	4.065GlyPro: 4.065 ± 0.047	2.757GlyGln: 2.757 ± 0.022	3.717GlyArg: 3.717 ± 0.022	5.705GlySer: 5.705 ± 0.033	3.546GlyThr: 3.546 ± 0.022	3.531GlyVal: 3.531 ± 0.021	0.771GlyTrp: 0.771 ± 0.009	1.727GlyTyr: 1.727 ± 0.017	0.013GlyXaa: 0.013 ± 0.001
His	1.318HisAla: 1.318 ± 0.01	0.692HisCys: 0.692 ± 0.009	0.896HisAsp: 0.896 ± 0.008	1.349HisGlu: 1.349 ± 0.01	1.086HisPhe: 1.086 ± 0.009	1.539HisGly: 1.539 ± 0.014	0.901HisHis: 0.901 ± 0.011	1.256HisIle: 1.256 ± 0.01	1.296HisLys: 1.296 ± 0.01	2.903HisLeu: 2.903 ± 0.015	0.617HisMet: 0.617 ± 0.007	0.877HisAsn: 0.877 ± 0.009	1.623HisPro: 1.623 ± 0.011	1.45HisGln: 1.45 ± 0.017	1.605HisArg: 1.605 ± 0.012	2.324HisSer: 2.324 ± 0.017	1.665HisThr: 1.665 ± 0.02	1.504HisVal: 1.504 ± 0.011	0.342HisTrp: 0.342 ± 0.005	0.811HisTyr: 0.811 ± 0.007	0.004HisXaa: 0.004 ± 0.001
Ile	2.595IleAla: 2.595 ± 0.015	1.094IleCys: 1.094 ± 0.009	2.071IleAsp: 2.071 ± 0.013	2.656IleGlu: 2.656 ± 0.021	1.92IlePhe: 1.92 ± 0.015	2.223IleGly: 2.223 ± 0.013	1.481IleHis: 1.481 ± 0.015	2.407IleIle: 2.407 ± 0.015	2.682IleLys: 2.682 ± 0.025	4.646IleLeu: 4.646 ± 0.023	1.029IleMet: 1.029 ± 0.008	1.804IleAsn: 1.804 ± 0.012	2.662IlePro: 2.662 ± 0.017	2.331IleGln: 2.331 ± 0.014	2.395IleArg: 2.395 ± 0.013	3.765IleSer: 3.765 ± 0.02	2.587IleThr: 2.587 ± 0.025	2.532IleVal: 2.532 ± 0.017	0.51IleTrp: 0.51 ± 0.006	1.382IleTyr: 1.382 ± 0.011	0.005IleXaa: 0.005 ± 0.0
Lys	4.082LysAla: 4.082 ± 0.025	1.203LysCys: 1.203 ± 0.013	3.253LysAsp: 3.253 ± 0.022	5.251LysGlu: 5.251 ± 0.032	1.766LysPhe: 1.766 ± 0.014	3.246LysGly: 3.246 ± 0.026	1.424LysHis: 1.424 ± 0.012	2.85LysIle: 2.85 ± 0.018	4.912LysLys: 4.912 ± 0.037	5.23LysLeu: 5.23 ± 0.027	1.496LysMet: 1.496 ± 0.013	2.467LysAsn: 2.467 ± 0.018	3.287LysPro: 3.287 ± 0.031	2.656LysGln: 2.656 ± 0.019	3.337LysArg: 3.337 ± 0.018	4.075LysSer: 4.075 ± 0.024	3.284LysThr: 3.284 ± 0.018	3.523LysVal: 3.523 ± 0.027	0.606LysTrp: 0.606 ± 0.009	1.59LysTyr: 1.59 ± 0.014	0.006LysXaa: 0.006 ± 0.001
Leu	6.698LeuAla: 6.698 ± 0.035	2.135LeuCys: 2.135 ± 0.016	4.744LeuAsp: 4.744 ± 0.021	7.189LeuGlu: 7.189 ± 0.041	3.363LeuPhe: 3.363 ± 0.019	5.812LeuGly: 5.812 ± 0.03	2.722LeuHis: 2.722 ± 0.015	3.955LeuIle: 3.955 ± 0.024	5.898LeuLys: 5.898 ± 0.034	10.582LeuLeu: 10.582 ± 0.056	2.063LeuMet: 2.063 ± 0.015	3.536LeuAsn: 3.536 ± 0.018	5.893LeuPro: 5.893 ± 0.03	5.721LeuGln: 5.721 ± 0.034	5.793LeuArg: 5.793 ± 0.028	7.957LeuSer: 7.957 ± 0.029	5.118LeuThr: 5.118 ± 0.021	5.532LeuVal: 5.532 ± 0.024	1.131LeuTrp: 1.131 ± 0.01	2.52LeuTyr: 2.52 ± 0.017	0.016LeuXaa: 0.016 ± 0.001
Met	1.972MetAla: 1.972 ± 0.013	0.408MetCys: 0.408 ± 0.006	1.291MetAsp: 1.291 ± 0.011	1.891MetGlu: 1.891 ± 0.012	0.76MetPhe: 0.76 ± 0.008	1.312MetGly: 1.312 ± 0.011	0.475MetHis: 0.475 ± 0.006	0.87MetIle: 0.87 ± 0.008	1.486MetLys: 1.486 ± 0.011	2.008MetLeu: 2.008 ± 0.014	0.6MetMet: 0.6 ± 0.007	0.923MetAsn: 0.923 ± 0.009	1.12MetPro: 1.12 ± 0.014	0.941MetGln: 0.941 ± 0.009	1.089MetArg: 1.089 ± 0.008	1.623MetSer: 1.623 ± 0.011	1.175MetThr: 1.175 ± 0.011	1.44MetVal: 1.44 ± 0.01	0.244MetTrp: 0.244 ± 0.004	0.594MetTyr: 0.594 ± 0.007	0.002MetXaa: 0.002 ± 0.0
Asn	2.062AsnAla: 2.062 ± 0.012	0.825AsnCys: 0.825 ± 0.009	1.542AsnAsp: 1.542 ± 0.012	2.267AsnGlu: 2.267 ± 0.017	1.498AsnPhe: 1.498 ± 0.013	2.407AsnGly: 2.407 ± 0.019	0.954AsnHis: 0.954 ± 0.008	2.121AsnIle: 2.121 ± 0.015	2.259AsnLys: 2.259 ± 0.014	3.775AsnLeu: 3.775 ± 0.02	0.94AsnMet: 0.94 ± 0.008	1.526AsnAsn: 1.526 ± 0.01	2.202AsnPro: 2.202 ± 0.013	1.683AsnGln: 1.683 ± 0.012	1.826AsnArg: 1.826 ± 0.012	3.179AsnSer: 3.179 ± 0.018	1.964AsnThr: 1.964 ± 0.011	2.215AsnVal: 2.215 ± 0.014	0.452AsnTrp: 0.452 ± 0.006	1.126AsnTyr: 1.126 ± 0.009	0.004AsnXaa: 0.004 ± 0.001
Pro	4.586ProAla: 4.586 ± 0.026	1.088ProCys: 1.088 ± 0.013	2.757ProAsp: 2.757 ± 0.018	4.404ProGlu: 4.404 ± 0.025	1.952ProPhe: 1.952 ± 0.012	5.094ProGly: 5.094 ± 0.064	1.401ProHis: 1.401 ± 0.01	1.931ProIle: 1.931 ± 0.019	2.833ProLys: 2.833 ± 0.025	5.142ProLeu: 5.142 ± 0.023	1.09ProMet: 1.09 ± 0.009	1.827ProAsn: 1.827 ± 0.013	5.805ProPro: 5.805 ± 0.055	2.776ProGln: 2.776 ± 0.021	3.269ProArg: 3.269 ± 0.02	5.678ProSer: 5.678 ± 0.03	3.104ProThr: 3.104 ± 0.018	3.842ProVal: 3.842 ± 0.022	0.673ProTrp: 0.673 ± 0.008	1.623ProTyr: 1.623 ± 0.018	0.014ProXaa: 0.014 ± 0.001
Gln	3.433GlnAla: 3.433 ± 0.023	0.915GlnCys: 0.915 ± 0.009	2.313GlnAsp: 2.313 ± 0.014	3.915GlnGlu: 3.915 ± 0.023	1.39GlnPhe: 1.39 ± 0.011	2.837GlnGly: 2.837 ± 0.018	1.32GlnHis: 1.32 ± 0.011	1.995GlnIle: 1.995 ± 0.011	3.054GlnLys: 3.054 ± 0.021	4.748GlnLeu: 4.748 ± 0.024	1.166GlnMet: 1.166 ± 0.01	1.86GlnAsn: 1.86 ± 0.012	2.758GlnPro: 2.758 ± 0.023	3.075GlnGln: 3.075 ± 0.036	3.009GlnArg: 3.009 ± 0.022	3.184GlnSer: 3.184 ± 0.019	2.33GlnThr: 2.33 ± 0.014	2.838GlnVal: 2.838 ± 0.015	0.534GlnTrp: 0.534 ± 0.006	1.167GlnTyr: 1.167 ± 0.009	0.005GlnXaa: 0.005 ± 0.001
Arg	3.682ArgAla: 3.682 ± 0.021	1.144ArgCys: 1.144 ± 0.013	2.74ArgAsp: 2.74 ± 0.014	4.029ArgGlu: 4.029 ± 0.023	1.857ArgPhe: 1.857 ± 0.011	3.546ArgGly: 3.546 ± 0.028	1.561ArgHis: 1.561 ± 0.013	2.499ArgIle: 2.499 ± 0.016	3.72ArgLys: 3.72 ± 0.021	5.338ArgLeu: 5.338 ± 0.026	1.212ArgMet: 1.212 ± 0.01	2.142ArgAsn: 2.142 ± 0.013	3.192ArgPro: 3.192 ± 0.018	2.588ArgGln: 2.588 ± 0.018	4.284ArgArg: 4.284 ± 0.028	4.327ArgSer: 4.327 ± 0.033	2.829ArgThr: 2.829 ± 0.015	3.212ArgVal: 3.212 ± 0.022	0.683ArgTrp: 0.683 ± 0.007	1.446ArgTyr: 1.446 ± 0.01	0.01ArgXaa: 0.01 ± 0.001
Ser	5.229SerAla: 5.229 ± 0.025	1.848SerCys: 1.848 ± 0.018	3.937SerAsp: 3.937 ± 0.022	5.285SerGlu: 5.285 ± 0.025	3.064SerPhe: 3.064 ± 0.016	5.587SerGly: 5.587 ± 0.034	2.17SerHis: 2.17 ± 0.015	3.258SerIle: 3.258 ± 0.015	4.211SerLys: 4.211 ± 0.024	8.19SerLeu: 8.19 ± 0.033	1.649SerMet: 1.649 ± 0.013	2.709SerAsn: 2.709 ± 0.016	5.948SerPro: 5.948 ± 0.036	3.975SerGln: 3.975 ± 0.025	4.586SerArg: 4.586 ± 0.028	9.414SerSer: 9.414 ± 0.061	4.482SerThr: 4.482 ± 0.028	4.918SerVal: 4.918 ± 0.023	1.071SerTrp: 1.071 ± 0.011	2.097SerTyr: 2.097 ± 0.014	0.012SerXaa: 0.012 ± 0.001
Thr	3.707ThrAla: 3.707 ± 0.018	1.276ThrCys: 1.276 ± 0.015	2.466ThrAsp: 2.466 ± 0.013	3.588ThrGlu: 3.588 ± 0.018	2.145ThrPhe: 2.145 ± 0.013	3.696ThrGly: 3.696 ± 0.028	1.382ThrHis: 1.382 ± 0.012	2.43ThrIle: 2.43 ± 0.018	2.72ThrLys: 2.72 ± 0.019	5.34ThrLeu: 5.34 ± 0.02	1.143ThrMet: 1.143 ± 0.009	1.747ThrAsn: 1.747 ± 0.013	3.551ThrPro: 3.551 ± 0.019	2.315ThrGln: 2.315 ± 0.014	2.519ThrArg: 2.519 ± 0.015	4.654ThrSer: 4.654 ± 0.031	3.012ThrThr: 3.012 ± 0.03	3.883ThrVal: 3.883 ± 0.023	0.691ThrTrp: 0.691 ± 0.009	1.403ThrTyr: 1.403 ± 0.011	0.007ThrXaa: 0.007 ± 0.001
Val	4.26ValAla: 4.26 ± 0.02	1.427ValCys: 1.427 ± 0.014	2.977ValAsp: 2.977 ± 0.017	3.849ValGlu: 3.849 ± 0.025	2.431ValPhe: 2.431 ± 0.016	3.371ValGly: 3.371 ± 0.019	1.593ValHis: 1.593 ± 0.012	2.993ValIle: 2.993 ± 0.016	3.47ValLys: 3.47 ± 0.026	6.231ValLeu: 6.231 ± 0.03	1.365ValMet: 1.365 ± 0.011	2.299ValAsn: 2.299 ± 0.016	3.658ValPro: 3.658 ± 0.026	2.712ValGln: 2.712 ± 0.015	2.991ValArg: 2.991 ± 0.019	4.947ValSer: 4.947 ± 0.025	3.842ValThr: 3.842 ± 0.031	4.033ValVal: 4.033 ± 0.023	0.707ValTrp: 0.707 ± 0.008	1.616ValTyr: 1.616 ± 0.011	0.007ValXaa: 0.007 ± 0.001
Trp	0.767TrpAla: 0.767 ± 0.008	0.242TrpCys: 0.242 ± 0.004	0.66TrpAsp: 0.66 ± 0.007	0.816TrpGlu: 0.816 ± 0.009	0.447TrpPhe: 0.447 ± 0.007	0.708TrpGly: 0.708 ± 0.007	0.313TrpHis: 0.313 ± 0.005	0.545TrpIle: 0.545 ± 0.006	0.807TrpLys: 0.807 ± 0.008	1.18TrpLeu: 1.18 ± 0.009	0.309TrpMet: 0.309 ± 0.004	0.547TrpAsn: 0.547 ± 0.007	0.506TrpPro: 0.506 ± 0.006	0.526TrpGln: 0.526 ± 0.006	0.714TrpArg: 0.714 ± 0.009	0.852TrpSer: 0.852 ± 0.01	0.674TrpThr: 0.674 ± 0.009	0.684TrpVal: 0.684 ± 0.008	0.188TrpTrp: 0.188 ± 0.004	0.341TrpTyr: 0.341 ± 0.006	0.002TrpXaa: 0.002 ± 0.0
Tyr	1.394TyrAla: 1.394 ± 0.01	0.666TyrCys: 0.666 ± 0.007	1.292TyrAsp: 1.292 ± 0.012	1.771TyrGlu: 1.771 ± 0.014	1.229TyrPhe: 1.229 ± 0.01	1.685TyrGly: 1.685 ± 0.015	0.757TyrHis: 0.757 ± 0.008	1.393TyrIle: 1.393 ± 0.012	1.522TyrLys: 1.522 ± 0.02	2.637TyrLeu: 2.637 ± 0.014	0.602TyrMet: 0.602 ± 0.006	1.113TyrAsn: 1.113 ± 0.011	1.296TyrPro: 1.296 ± 0.01	1.271TyrGln: 1.271 ± 0.009	1.575TyrArg: 1.575 ± 0.012	2.202TyrSer: 2.202 ± 0.014	1.477TyrThr: 1.477 ± 0.012	1.604TyrVal: 1.604 ± 0.013	0.348TyrTrp: 0.348 ± 0.006	0.938TyrTyr: 0.938 ± 0.009	0.003TyrXaa: 0.003 ± 0.0
Xaa	0.011XaaAla: 0.011 ± 0.001	0.003XaaCys: 0.003 ± 0.0	0.004XaaAsp: 0.004 ± 0.001	0.008XaaGlu: 0.008 ± 0.001	0.005XaaPhe: 0.005 ± 0.001	0.012XaaGly: 0.012 ± 0.001	0.005XaaHis: 0.005 ± 0.001	0.006XaaIle: 0.006 ± 0.001	0.008XaaLys: 0.008 ± 0.001	0.014XaaLeu: 0.014 ± 0.001	0.003XaaMet: 0.003 ± 0.0	0.004XaaAsn: 0.004 ± 0.001	0.015XaaPro: 0.015 ± 0.001	0.006XaaGln: 0.006 ± 0.001	0.009XaaArg: 0.009 ± 0.001	0.01XaaSer: 0.01 ± 0.001	0.006XaaThr: 0.006 ± 0.001	0.007XaaVal: 0.007 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.003XaaTyr: 0.003 ± 0.0	0.289XaaXaa: 0.289 ± 0.021

Statistics based on 30311 proteins (16244683 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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