Amino acid dipepetide frequency for Alligator sinensis (Chinese alligator)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.065AlaAla: 6.065 ± 0.03	1.313AlaCys: 1.313 ± 0.01	2.938AlaAsp: 2.938 ± 0.012	4.753AlaGlu: 4.753 ± 0.022	2.341AlaPhe: 2.341 ± 0.013	4.194AlaGly: 4.194 ± 0.019	1.417AlaHis: 1.417 ± 0.008	2.846AlaIle: 2.846 ± 0.014	3.86AlaLys: 3.86 ± 0.027	6.506AlaLeu: 6.506 ± 0.022	1.526AlaMet: 1.526 ± 0.009	2.195AlaAsn: 2.195 ± 0.011	3.535AlaPro: 3.535 ± 0.026	3.036AlaGln: 3.036 ± 0.014	3.197AlaArg: 3.197 ± 0.016	5.63AlaSer: 5.63 ± 0.021	3.533AlaThr: 3.533 ± 0.017	4.684AlaVal: 4.684 ± 0.018	0.749AlaTrp: 0.749 ± 0.007	1.547AlaTyr: 1.547 ± 0.012	0.008AlaXaa: 0.008 ± 0.001
Cys	1.146CysAla: 1.146 ± 0.01	0.589CysCys: 0.589 ± 0.006	0.992CysAsp: 0.992 ± 0.012	1.294CysGlu: 1.294 ± 0.014	0.821CysPhe: 0.821 ± 0.007	1.533CysGly: 1.533 ± 0.015	0.643CysHis: 0.643 ± 0.008	1.062CysIle: 1.062 ± 0.009	1.239CysLys: 1.239 ± 0.009	2.084CysLeu: 2.084 ± 0.015	0.444CysMet: 0.444 ± 0.004	0.855CysAsn: 0.855 ± 0.008	1.274CysPro: 1.274 ± 0.012	1.041CysGln: 1.041 ± 0.012	1.167CysArg: 1.167 ± 0.01	2.039CysSer: 2.039 ± 0.016	1.181CysThr: 1.181 ± 0.011	1.222CysVal: 1.222 ± 0.011	0.27CysTrp: 0.27 ± 0.003	0.607CysTyr: 0.607 ± 0.006	0.002CysXaa: 0.002 ± 0.0
Asp	3.037AspAla: 3.037 ± 0.015	1.101AspCys: 1.101 ± 0.01	2.746AspAsp: 2.746 ± 0.015	3.567AspGlu: 3.567 ± 0.019	2.09AspPhe: 2.09 ± 0.01	3.245AspGly: 3.245 ± 0.019	1.139AspHis: 1.139 ± 0.008	2.823AspIle: 2.823 ± 0.018	2.849AspLys: 2.849 ± 0.017	5.013AspLeu: 5.013 ± 0.018	1.206AspMet: 1.206 ± 0.009	1.841AspAsn: 1.841 ± 0.01	2.707AspPro: 2.707 ± 0.014	1.952AspGln: 1.952 ± 0.01	2.363AspArg: 2.363 ± 0.014	4.381AspSer: 4.381 ± 0.021	2.619AspThr: 2.619 ± 0.016	3.076AspVal: 3.076 ± 0.016	0.601AspTrp: 0.601 ± 0.006	1.579AspTyr: 1.579 ± 0.013	0.003AspXaa: 0.003 ± 0.0
Glu	4.898GluAla: 4.898 ± 0.02	1.31GluCys: 1.31 ± 0.012	4.55GluAsp: 4.55 ± 0.022	8.245GluGlu: 8.245 ± 0.042	2.041GluPhe: 2.041 ± 0.012	4.093GluGly: 4.093 ± 0.019	1.607GluHis: 1.607 ± 0.01	3.481GluIle: 3.481 ± 0.019	5.956GluLys: 5.956 ± 0.038	6.503GluLeu: 6.503 ± 0.03	1.904GluMet: 1.904 ± 0.01	3.394GluAsn: 3.394 ± 0.017	2.988GluPro: 2.988 ± 0.017	3.4GluGln: 3.4 ± 0.018	3.993GluArg: 3.993 ± 0.023	4.736GluSer: 4.736 ± 0.023	3.748GluThr: 3.748 ± 0.018	4.217GluVal: 4.217 ± 0.019	0.71GluTrp: 0.71 ± 0.008	1.731GluTyr: 1.731 ± 0.014	0.005GluXaa: 0.005 ± 0.0
Phe	1.915PheAla: 1.915 ± 0.012	0.911PheCys: 0.911 ± 0.008	1.715PheAsp: 1.715 ± 0.013	1.981PheGlu: 1.981 ± 0.01	1.521PhePhe: 1.521 ± 0.012	2.042PheGly: 2.042 ± 0.014	1.016PheHis: 1.016 ± 0.008	1.852PheIle: 1.852 ± 0.012	1.823PheLys: 1.823 ± 0.013	3.765PheLeu: 3.765 ± 0.021	0.773PheMet: 0.773 ± 0.007	1.404PheAsn: 1.404 ± 0.01	1.878PhePro: 1.878 ± 0.011	1.719PheGln: 1.719 ± 0.01	1.72PheArg: 1.72 ± 0.01	3.227PheSer: 3.227 ± 0.014	2.131PheThr: 2.131 ± 0.014	2.007PheVal: 2.007 ± 0.011	0.455PheTrp: 0.455 ± 0.005	1.138PheTyr: 1.138 ± 0.009	0.004PheXaa: 0.004 ± 0.0
Gly	3.806GlyAla: 3.806 ± 0.021	1.217GlyCys: 1.217 ± 0.011	2.982GlyAsp: 2.982 ± 0.017	4.041GlyGlu: 4.041 ± 0.027	2.266GlyPhe: 2.266 ± 0.017	4.053GlyGly: 4.053 ± 0.029	1.557GlyHis: 1.557 ± 0.011	2.892GlyIle: 2.892 ± 0.013	4.006GlyLys: 4.006 ± 0.021	5.205GlyLeu: 5.205 ± 0.03	1.33GlyMet: 1.33 ± 0.009	2.473GlyAsn: 2.473 ± 0.013	3.316GlyPro: 3.316 ± 0.045	2.739GlyGln: 2.739 ± 0.016	3.296GlyArg: 3.296 ± 0.018	5.482GlySer: 5.482 ± 0.024	3.572GlyThr: 3.572 ± 0.018	3.287GlyVal: 3.287 ± 0.02	0.766GlyTrp: 0.766 ± 0.009	1.782GlyTyr: 1.782 ± 0.013	0.008GlyXaa: 0.008 ± 0.001
His	1.392HisAla: 1.392 ± 0.009	0.731HisCys: 0.731 ± 0.008	0.965HisAsp: 0.965 ± 0.009	1.395HisGlu: 1.395 ± 0.009	1.042HisPhe: 1.042 ± 0.007	1.512HisGly: 1.512 ± 0.012	0.898HisHis: 0.898 ± 0.008	1.355HisIle: 1.355 ± 0.011	1.398HisLys: 1.398 ± 0.009	2.839HisLeu: 2.839 ± 0.014	0.606HisMet: 0.606 ± 0.006	0.968HisAsn: 0.968 ± 0.008	1.575HisPro: 1.575 ± 0.01	1.422HisGln: 1.422 ± 0.013	1.499HisArg: 1.499 ± 0.01	2.271HisSer: 2.271 ± 0.013	1.476HisThr: 1.476 ± 0.01	1.498HisVal: 1.498 ± 0.01	0.336HisTrp: 0.336 ± 0.004	0.853HisTyr: 0.853 ± 0.007	0.002HisXaa: 0.002 ± 0.0
Ile	2.801IleAla: 2.801 ± 0.014	1.128IleCys: 1.128 ± 0.008	2.163IleAsp: 2.163 ± 0.012	2.804IleGlu: 2.804 ± 0.014	1.863IlePhe: 1.863 ± 0.012	2.33IleGly: 2.33 ± 0.014	1.419IleHis: 1.419 ± 0.011	2.581IleIle: 2.581 ± 0.013	2.928IleLys: 2.928 ± 0.017	4.594IleLeu: 4.594 ± 0.02	1.051IleMet: 1.051 ± 0.008	2.047IleAsn: 2.047 ± 0.01	2.762IlePro: 2.762 ± 0.013	2.527IleGln: 2.527 ± 0.012	2.351IleArg: 2.351 ± 0.011	4.123IleSer: 4.123 ± 0.017	2.868IleThr: 2.868 ± 0.015	2.629IleVal: 2.629 ± 0.013	0.509IleTrp: 0.509 ± 0.005	1.435IleTyr: 1.435 ± 0.01	0.004IleXaa: 0.004 ± 0.0
Lys	4.107LysAla: 4.107 ± 0.022	1.163LysCys: 1.163 ± 0.01	3.531LysAsp: 3.531 ± 0.02	5.825LysGlu: 5.825 ± 0.035	1.79LysPhe: 1.79 ± 0.013	3.476LysGly: 3.476 ± 0.028	1.586LysHis: 1.586 ± 0.012	2.981LysIle: 2.981 ± 0.016	5.337LysLys: 5.337 ± 0.037	5.51LysLeu: 5.51 ± 0.023	1.629LysMet: 1.629 ± 0.012	2.697LysAsn: 2.697 ± 0.014	3.431LysPro: 3.431 ± 0.026	3.092LysGln: 3.092 ± 0.018	3.521LysArg: 3.521 ± 0.017	4.421LysSer: 4.421 ± 0.023	3.44LysThr: 3.44 ± 0.02	3.654LysVal: 3.654 ± 0.021	0.653LysTrp: 0.653 ± 0.007	1.778LysTyr: 1.778 ± 0.021	0.004LysXaa: 0.004 ± 0.0
Leu	6.314LeuAla: 6.314 ± 0.022	2.01LeuCys: 2.01 ± 0.012	4.676LeuAsp: 4.676 ± 0.016	7.165LeuGlu: 7.165 ± 0.034	3.104LeuPhe: 3.104 ± 0.02	5.155LeuGly: 5.155 ± 0.023	2.769LeuHis: 2.769 ± 0.016	3.945LeuIle: 3.945 ± 0.017	6.164LeuLys: 6.164 ± 0.026	9.661LeuLeu: 9.661 ± 0.043	2.0LeuMet: 2.0 ± 0.01	3.704LeuAsn: 3.704 ± 0.015	5.595LeuPro: 5.595 ± 0.022	5.77LeuGln: 5.77 ± 0.025	5.216LeuArg: 5.216 ± 0.02	7.907LeuSer: 7.907 ± 0.025	4.894LeuThr: 4.894 ± 0.017	5.145LeuVal: 5.145 ± 0.018	1.012LeuTrp: 1.012 ± 0.009	2.586LeuTyr: 2.586 ± 0.015	0.01LeuXaa: 0.01 ± 0.001
Met	1.739MetAla: 1.739 ± 0.01	0.405MetCys: 0.405 ± 0.005	1.303MetAsp: 1.303 ± 0.008	2.03MetGlu: 2.03 ± 0.011	0.768MetPhe: 0.768 ± 0.007	1.282MetGly: 1.282 ± 0.01	0.548MetHis: 0.548 ± 0.005	0.907MetIle: 0.907 ± 0.007	1.606MetLys: 1.606 ± 0.01	2.058MetLeu: 2.058 ± 0.013	0.616MetMet: 0.616 ± 0.006	0.995MetAsn: 0.995 ± 0.008	1.192MetPro: 1.192 ± 0.012	1.142MetGln: 1.142 ± 0.008	1.077MetArg: 1.077 ± 0.008	1.667MetSer: 1.667 ± 0.009	1.156MetThr: 1.156 ± 0.007	1.406MetVal: 1.406 ± 0.008	0.247MetTrp: 0.247 ± 0.004	0.635MetTyr: 0.635 ± 0.006	0.001MetXaa: 0.001 ± 0.0
Asn	2.277AsnAla: 2.277 ± 0.011	0.883AsnCys: 0.883 ± 0.009	1.681AsnAsp: 1.681 ± 0.01	2.548AsnGlu: 2.548 ± 0.014	1.468AsnPhe: 1.468 ± 0.009	2.626AsnGly: 2.626 ± 0.019	0.996AsnHis: 0.996 ± 0.007	2.347AsnIle: 2.347 ± 0.014	2.548AsnLys: 2.548 ± 0.015	3.896AsnLeu: 3.896 ± 0.018	1.021AsnMet: 1.021 ± 0.008	1.752AsnAsn: 1.752 ± 0.011	2.185AsnPro: 2.185 ± 0.013	1.846AsnGln: 1.846 ± 0.011	1.918AsnArg: 1.918 ± 0.01	3.408AsnSer: 3.408 ± 0.016	2.22AsnThr: 2.22 ± 0.011	2.335AsnVal: 2.335 ± 0.012	0.454AsnTrp: 0.454 ± 0.004	1.188AsnTyr: 1.188 ± 0.009	0.003AsnXaa: 0.003 ± 0.0
Pro	4.352ProAla: 4.352 ± 0.024	1.048ProCys: 1.048 ± 0.011	2.802ProAsp: 2.802 ± 0.02	4.095ProGlu: 4.095 ± 0.021	1.821ProPhe: 1.821 ± 0.012	4.422ProGly: 4.422 ± 0.06	1.417ProHis: 1.417 ± 0.009	2.062ProIle: 2.062 ± 0.012	2.91ProLys: 2.91 ± 0.025	4.773ProLeu: 4.773 ± 0.019	1.07ProMet: 1.07 ± 0.008	1.871ProAsn: 1.871 ± 0.012	5.161ProPro: 5.161 ± 0.046	2.752ProGln: 2.752 ± 0.019	2.735ProArg: 2.735 ± 0.015	5.507ProSer: 5.507 ± 0.03	2.995ProThr: 2.995 ± 0.017	3.922ProVal: 3.922 ± 0.019	0.586ProTrp: 0.586 ± 0.006	1.404ProTyr: 1.404 ± 0.01	0.008ProXaa: 0.008 ± 0.001
Gln	3.399GlnAla: 3.399 ± 0.016	1.034GlnCys: 1.034 ± 0.011	2.368GlnAsp: 2.368 ± 0.011	4.015GlnGlu: 4.015 ± 0.017	1.401GlnPhe: 1.401 ± 0.009	2.759GlnGly: 2.759 ± 0.017	1.438GlnHis: 1.438 ± 0.009	2.138GlnIle: 2.138 ± 0.013	3.287GlnLys: 3.287 ± 0.016	4.762GlnLeu: 4.762 ± 0.021	1.19GlnMet: 1.19 ± 0.008	2.119GlnAsn: 2.119 ± 0.011	2.698GlnPro: 2.698 ± 0.018	3.472GlnGln: 3.472 ± 0.028	2.856GlnArg: 2.856 ± 0.015	3.467GlnSer: 3.467 ± 0.015	2.478GlnThr: 2.478 ± 0.012	2.777GlnVal: 2.777 ± 0.013	0.545GlnTrp: 0.545 ± 0.006	1.337GlnTyr: 1.337 ± 0.012	0.004GlnXaa: 0.004 ± 0.0
Arg	3.229ArgAla: 3.229 ± 0.013	1.114ArgCys: 1.114 ± 0.011	2.616ArgAsp: 2.616 ± 0.013	3.825ArgGlu: 3.825 ± 0.021	1.702ArgPhe: 1.702 ± 0.011	3.118ArgGly: 3.118 ± 0.021	1.508ArgHis: 1.508 ± 0.011	2.472ArgIle: 2.472 ± 0.014	3.754ArgLys: 3.754 ± 0.017	4.796ArgLeu: 4.796 ± 0.02	1.188ArgMet: 1.188 ± 0.008	2.128ArgAsn: 2.128 ± 0.01	2.697ArgPro: 2.697 ± 0.013	2.571ArgGln: 2.571 ± 0.012	3.826ArgArg: 3.826 ± 0.023	4.167ArgSer: 4.167 ± 0.027	2.764ArgThr: 2.764 ± 0.013	2.898ArgVal: 2.898 ± 0.014	0.616ArgTrp: 0.616 ± 0.006	1.544ArgTyr: 1.544 ± 0.012	0.007ArgXaa: 0.007 ± 0.001
Ser	5.328SerAla: 5.328 ± 0.021	1.83SerCys: 1.83 ± 0.014	4.219SerAsp: 4.219 ± 0.028	5.419SerGlu: 5.419 ± 0.024	3.147SerPhe: 3.147 ± 0.019	5.15SerGly: 5.15 ± 0.023	2.171SerHis: 2.171 ± 0.013	3.56SerIle: 3.56 ± 0.015	4.588SerLys: 4.588 ± 0.023	8.095SerLeu: 8.095 ± 0.027	1.722SerMet: 1.722 ± 0.009	3.099SerAsn: 3.099 ± 0.014	5.758SerPro: 5.758 ± 0.033	3.993SerGln: 3.993 ± 0.017	4.294SerArg: 4.294 ± 0.023	9.916SerSer: 9.916 ± 0.053	4.919SerThr: 4.919 ± 0.025	5.038SerVal: 5.038 ± 0.018	1.044SerTrp: 1.044 ± 0.012	2.178SerTyr: 2.178 ± 0.011	0.007SerXaa: 0.007 ± 0.001
Thr	3.984ThrAla: 3.984 ± 0.021	1.37ThrCys: 1.37 ± 0.016	2.732ThrAsp: 2.732 ± 0.013	3.99ThrGlu: 3.99 ± 0.016	1.966ThrPhe: 1.966 ± 0.011	3.572ThrGly: 3.572 ± 0.017	1.291ThrHis: 1.291 ± 0.012	2.589ThrIle: 2.589 ± 0.014	2.966ThrLys: 2.966 ± 0.015	5.101ThrLeu: 5.101 ± 0.017	1.184ThrMet: 1.184 ± 0.006	1.958ThrAsn: 1.958 ± 0.01	3.575ThrPro: 3.575 ± 0.024	2.312ThrGln: 2.312 ± 0.012	2.378ThrArg: 2.378 ± 0.011	4.955ThrSer: 4.955 ± 0.024	3.275ThrThr: 3.275 ± 0.032	4.137ThrVal: 4.137 ± 0.03	0.683ThrTrp: 0.683 ± 0.006	1.449ThrTyr: 1.449 ± 0.009	0.005ThrXaa: 0.005 ± 0.001
Val	3.981ValAla: 3.981 ± 0.016	1.418ValCys: 1.418 ± 0.011	2.954ValAsp: 2.954 ± 0.016	3.976ValGlu: 3.976 ± 0.017	2.246ValPhe: 2.246 ± 0.013	3.137ValGly: 3.137 ± 0.017	1.565ValHis: 1.565 ± 0.009	2.979ValIle: 2.979 ± 0.014	3.72ValLys: 3.72 ± 0.023	5.896ValLeu: 5.896 ± 0.019	1.342ValMet: 1.342 ± 0.009	2.396ValAsn: 2.396 ± 0.013	3.678ValPro: 3.678 ± 0.026	2.932ValGln: 2.932 ± 0.016	2.795ValArg: 2.795 ± 0.015	4.943ValSer: 4.943 ± 0.021	3.886ValThr: 3.886 ± 0.023	3.825ValVal: 3.825 ± 0.017	0.653ValTrp: 0.653 ± 0.005	1.617ValTyr: 1.617 ± 0.01	0.005ValXaa: 0.005 ± 0.0
Trp	0.673TrpAla: 0.673 ± 0.007	0.243TrpCys: 0.243 ± 0.004	0.613TrpAsp: 0.613 ± 0.005	0.802TrpGlu: 0.802 ± 0.007	0.397TrpPhe: 0.397 ± 0.005	0.649TrpGly: 0.649 ± 0.009	0.294TrpHis: 0.294 ± 0.004	0.566TrpIle: 0.566 ± 0.006	0.839TrpLys: 0.839 ± 0.007	1.159TrpLeu: 1.159 ± 0.009	0.32TrpMet: 0.32 ± 0.004	0.517TrpAsn: 0.517 ± 0.006	0.444TrpPro: 0.444 ± 0.005	0.522TrpGln: 0.522 ± 0.005	0.664TrpArg: 0.664 ± 0.007	0.859TrpSer: 0.859 ± 0.009	0.703TrpThr: 0.703 ± 0.011	0.625TrpVal: 0.625 ± 0.006	0.168TrpTrp: 0.168 ± 0.003	0.342TrpTyr: 0.342 ± 0.005	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.424TyrAla: 1.424 ± 0.009	0.686TyrCys: 0.686 ± 0.006	1.388TyrAsp: 1.388 ± 0.012	1.735TyrGlu: 1.735 ± 0.012	1.198TyrPhe: 1.198 ± 0.008	1.721TyrGly: 1.721 ± 0.016	0.753TyrHis: 0.753 ± 0.007	1.474TyrIle: 1.474 ± 0.01	1.845TyrLys: 1.845 ± 0.032	2.576TyrLeu: 2.576 ± 0.014	0.655TyrMet: 0.655 ± 0.005	1.186TyrAsn: 1.186 ± 0.009	1.258TyrPro: 1.258 ± 0.01	1.3TyrGln: 1.3 ± 0.008	1.667TyrArg: 1.667 ± 0.016	2.362TyrSer: 2.362 ± 0.012	1.607TyrThr: 1.607 ± 0.013	1.555TyrVal: 1.555 ± 0.011	0.342TyrTrp: 0.342 ± 0.006	0.992TyrTyr: 0.992 ± 0.007	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.007XaaAla: 0.007 ± 0.001	0.002XaaCys: 0.002 ± 0.0	0.002XaaAsp: 0.002 ± 0.0	0.006XaaGlu: 0.006 ± 0.0	0.003XaaPhe: 0.003 ± 0.0	0.007XaaGly: 0.007 ± 0.001	0.002XaaHis: 0.002 ± 0.0	0.004XaaIle: 0.004 ± 0.0	0.004XaaLys: 0.004 ± 0.0	0.01XaaLeu: 0.01 ± 0.001	0.002XaaMet: 0.002 ± 0.0	0.003XaaAsn: 0.003 ± 0.0	0.007XaaPro: 0.007 ± 0.001	0.005XaaGln: 0.005 ± 0.0	0.007XaaArg: 0.007 ± 0.001	0.007XaaSer: 0.007 ± 0.001	0.003XaaThr: 0.003 ± 0.0	0.004XaaVal: 0.004 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.002XaaTyr: 0.002 ± 0.0	0.44XaaXaa: 0.44 ± 0.017

Statistics based on 34942 proteins (23347094 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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