Amino acid dipepetide frequency for Hansschlegelia zhihuaiae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.592AlaAla: 21.592 ± 0.213	1.132AlaCys: 1.132 ± 0.032	7.52AlaAsp: 7.52 ± 0.094	9.002AlaGlu: 9.002 ± 0.109	5.048AlaPhe: 5.048 ± 0.082	11.748AlaGly: 11.748 ± 0.121	2.273AlaHis: 2.273 ± 0.046	6.385AlaIle: 6.385 ± 0.093	4.497AlaLys: 4.497 ± 0.073	15.073AlaLeu: 15.073 ± 0.137	3.311AlaMet: 3.311 ± 0.044	2.574AlaAsn: 2.574 ± 0.049	7.325AlaPro: 7.325 ± 0.104	3.7AlaGln: 3.7 ± 0.055	10.886AlaArg: 10.886 ± 0.109	6.943AlaSer: 6.943 ± 0.095	6.424AlaThr: 6.424 ± 0.071	9.615AlaVal: 9.615 ± 0.098	1.558AlaTrp: 1.558 ± 0.038	2.618AlaTyr: 2.618 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.063CysAla: 1.063 ± 0.032	0.11CysCys: 0.11 ± 0.009	0.492CysAsp: 0.492 ± 0.019	0.448CysGlu: 0.448 ± 0.019	0.287CysPhe: 0.287 ± 0.016	0.905CysGly: 0.905 ± 0.026	0.203CysHis: 0.203 ± 0.013	0.262CysIle: 0.262 ± 0.016	0.158CysLys: 0.158 ± 0.011	0.693CysLeu: 0.693 ± 0.026	0.143CysMet: 0.143 ± 0.01	0.156CysAsn: 0.156 ± 0.011	0.455CysPro: 0.455 ± 0.021	0.172CysGln: 0.172 ± 0.013	0.633CysArg: 0.633 ± 0.024	0.45CysSer: 0.45 ± 0.02	0.275CysThr: 0.275 ± 0.015	0.655CysVal: 0.655 ± 0.024	0.107CysTrp: 0.107 ± 0.009	0.154CysTyr: 0.154 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	8.155AspAla: 8.155 ± 0.092	0.453AspCys: 0.453 ± 0.02	3.907AspAsp: 3.907 ± 0.091	3.907AspGlu: 3.907 ± 0.057	2.174AspPhe: 2.174 ± 0.046	6.095AspGly: 6.095 ± 0.087	1.225AspHis: 1.225 ± 0.031	2.277AspIle: 2.277 ± 0.044	1.583AspLys: 1.583 ± 0.034	6.14AspLeu: 6.14 ± 0.073	1.155AspMet: 1.155 ± 0.029	1.07AspAsn: 1.07 ± 0.036	3.748AspPro: 3.748 ± 0.055	1.582AspGln: 1.582 ± 0.042	5.154AspArg: 5.154 ± 0.072	1.87AspSer: 1.87 ± 0.041	2.11AspThr: 2.11 ± 0.066	5.028AspVal: 5.028 ± 0.067	0.944AspTrp: 0.944 ± 0.025	1.348AspTyr: 1.348 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	9.042GluAla: 9.042 ± 0.104	0.318GluCys: 0.318 ± 0.017	2.961GluAsp: 2.961 ± 0.053	3.169GluGlu: 3.169 ± 0.062	1.724GluPhe: 1.724 ± 0.036	4.843GluGly: 4.843 ± 0.064	1.144GluHis: 1.144 ± 0.029	3.62GluIle: 3.62 ± 0.057	2.165GluLys: 2.165 ± 0.049	5.734GluLeu: 5.734 ± 0.057	1.361GluMet: 1.361 ± 0.034	1.331GluAsn: 1.331 ± 0.031	3.215GluPro: 3.215 ± 0.063	1.87GluGln: 1.87 ± 0.044	5.816GluArg: 5.816 ± 0.081	2.312GluSer: 2.312 ± 0.041	3.833GluThr: 3.833 ± 0.053	3.968GluVal: 3.968 ± 0.057	0.673GluTrp: 0.673 ± 0.024	0.812GluTyr: 0.812 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	4.99PheAla: 4.99 ± 0.071	0.36PheCys: 0.36 ± 0.02	2.741PheAsp: 2.741 ± 0.048	2.344PheGlu: 2.344 ± 0.042	1.379PhePhe: 1.379 ± 0.04	3.873PheGly: 3.873 ± 0.059	0.644PheHis: 0.644 ± 0.022	1.293PheIle: 1.293 ± 0.032	0.96PheLys: 0.96 ± 0.024	3.162PheLeu: 3.162 ± 0.059	0.665PheMet: 0.665 ± 0.024	0.862PheAsn: 0.862 ± 0.03	1.656PhePro: 1.656 ± 0.039	0.902PheGln: 0.902 ± 0.027	2.627PheArg: 2.627 ± 0.055	2.041PheSer: 2.041 ± 0.04	1.687PheThr: 1.687 ± 0.04	3.024PheVal: 3.024 ± 0.058	0.516PheTrp: 0.516 ± 0.023	0.804PheTyr: 0.804 ± 0.027	0.001PheXaa: 0.001 ± 0.001
Gly	11.777GlyAla: 11.777 ± 0.115	0.794GlyCys: 0.794 ± 0.025	5.313GlyAsp: 5.313 ± 0.119	5.399GlyGlu: 5.399 ± 0.073	3.772GlyPhe: 3.772 ± 0.05	8.652GlyGly: 8.652 ± 0.173	1.753GlyHis: 1.753 ± 0.04	2.896GlyIle: 2.896 ± 0.057	2.97GlyLys: 2.97 ± 0.061	9.261GlyLeu: 9.261 ± 0.093	2.016GlyMet: 2.016 ± 0.042	1.522GlyAsn: 1.522 ± 0.042	4.18GlyPro: 4.18 ± 0.059	2.479GlyGln: 2.479 ± 0.047	7.577GlyArg: 7.577 ± 0.089	4.705GlySer: 4.705 ± 0.078	3.409GlyThr: 3.409 ± 0.054	7.732GlyVal: 7.732 ± 0.086	1.425GlyTrp: 1.425 ± 0.042	2.149GlyTyr: 2.149 ± 0.046	0.002GlyXaa: 0.002 ± 0.001
His	2.289HisAla: 2.289 ± 0.045	0.21HisCys: 0.21 ± 0.014	1.186HisAsp: 1.186 ± 0.034	1.006HisGlu: 1.006 ± 0.033	0.71HisPhe: 0.71 ± 0.022	1.912HisGly: 1.912 ± 0.041	0.459HisHis: 0.459 ± 0.024	0.688HisIle: 0.688 ± 0.022	0.425HisLys: 0.425 ± 0.018	1.849HisLeu: 1.849 ± 0.042	0.404HisMet: 0.404 ± 0.018	0.362HisAsn: 0.362 ± 0.018	1.239HisPro: 1.239 ± 0.033	0.479HisGln: 0.479 ± 0.022	1.317HisArg: 1.317 ± 0.036	0.747HisSer: 0.747 ± 0.025	0.621HisThr: 0.621 ± 0.025	1.56HisVal: 1.56 ± 0.03	0.286HisTrp: 0.286 ± 0.015	0.42HisTyr: 0.42 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	6.77IleAla: 6.77 ± 0.071	0.397IleCys: 0.397 ± 0.019	3.373IleAsp: 3.373 ± 0.055	3.456IleGlu: 3.456 ± 0.057	1.44IlePhe: 1.44 ± 0.036	4.472IleGly: 4.472 ± 0.058	0.783IleHis: 0.783 ± 0.024	1.37IleIle: 1.37 ± 0.037	1.191IleLys: 1.191 ± 0.032	3.661IleLeu: 3.661 ± 0.059	0.755IleMet: 0.755 ± 0.025	1.004IleAsn: 1.004 ± 0.027	1.905IlePro: 1.905 ± 0.035	0.937IleGln: 0.937 ± 0.032	3.089IleArg: 3.089 ± 0.054	2.262IleSer: 2.262 ± 0.051	1.948IleThr: 1.948 ± 0.046	4.14IleVal: 4.14 ± 0.06	0.476IleTrp: 0.476 ± 0.021	0.97IleTyr: 0.97 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	4.374LysAla: 4.374 ± 0.08	0.145LysCys: 0.145 ± 0.011	1.817LysAsp: 1.817 ± 0.044	1.521LysGlu: 1.521 ± 0.037	0.817LysPhe: 0.817 ± 0.026	2.706LysGly: 2.706 ± 0.053	0.515LysHis: 0.515 ± 0.022	1.641LysIle: 1.641 ± 0.034	1.237LysLys: 1.237 ± 0.042	3.169LysLeu: 3.169 ± 0.05	0.606LysMet: 0.606 ± 0.02	0.765LysAsn: 0.765 ± 0.022	2.133LysPro: 2.133 ± 0.045	0.847LysGln: 0.847 ± 0.028	2.549LysArg: 2.549 ± 0.048	1.793LysSer: 1.793 ± 0.039	1.953LysThr: 1.953 ± 0.042	2.387LysVal: 2.387 ± 0.05	0.322LysTrp: 0.322 ± 0.017	0.546LysTyr: 0.546 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	14.998LeuAla: 14.998 ± 0.147	0.801LeuCys: 0.801 ± 0.028	6.4LeuAsp: 6.4 ± 0.083	5.337LeuGlu: 5.337 ± 0.075	3.44LeuPhe: 3.44 ± 0.057	8.641LeuGly: 8.641 ± 0.103	1.661LeuHis: 1.661 ± 0.039	4.463LeuIle: 4.463 ± 0.071	3.826LeuLys: 3.826 ± 0.062	8.509LeuLeu: 8.509 ± 0.122	1.977LeuMet: 1.977 ± 0.04	2.169LeuAsn: 2.169 ± 0.039	5.188LeuPro: 5.188 ± 0.064	2.258LeuGln: 2.258 ± 0.045	6.867LeuArg: 6.867 ± 0.07	6.058LeuSer: 6.058 ± 0.075	5.257LeuThr: 5.257 ± 0.067	7.81LeuVal: 7.81 ± 0.085	1.151LeuTrp: 1.151 ± 0.027	1.87LeuTyr: 1.87 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.772MetAla: 2.772 ± 0.046	0.137MetCys: 0.137 ± 0.011	0.935MetAsp: 0.935 ± 0.028	0.915MetGlu: 0.915 ± 0.027	0.613MetPhe: 0.613 ± 0.024	1.539MetGly: 1.539 ± 0.034	0.347MetHis: 0.347 ± 0.018	1.162MetIle: 1.162 ± 0.034	0.812MetLys: 0.812 ± 0.022	2.123MetLeu: 2.123 ± 0.039	0.505MetMet: 0.505 ± 0.02	0.568MetAsn: 0.568 ± 0.021	1.292MetPro: 1.292 ± 0.035	0.558MetGln: 0.558 ± 0.02	1.829MetArg: 1.829 ± 0.037	1.593MetSer: 1.593 ± 0.033	1.826MetThr: 1.826 ± 0.04	1.36MetVal: 1.36 ± 0.035	0.167MetTrp: 0.167 ± 0.011	0.239MetTyr: 0.239 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.809AsnAla: 2.809 ± 0.047	0.192AsnCys: 0.192 ± 0.012	1.281AsnAsp: 1.281 ± 0.04	1.061AsnGlu: 1.061 ± 0.028	0.812AsnPhe: 0.812 ± 0.025	1.995AsnGly: 1.995 ± 0.044	0.438AsnHis: 0.438 ± 0.017	0.903AsnIle: 0.903 ± 0.029	0.592AsnLys: 0.592 ± 0.024	2.104AsnLeu: 2.104 ± 0.043	0.431AsnMet: 0.431 ± 0.018	0.488AsnAsn: 0.488 ± 0.021	1.512AsnPro: 1.512 ± 0.036	0.576AsnGln: 0.576 ± 0.021	1.567AsnArg: 1.567 ± 0.039	0.922AsnSer: 0.922 ± 0.029	0.835AsnThr: 0.835 ± 0.025	1.92AsnVal: 1.92 ± 0.042	0.32AsnTrp: 0.32 ± 0.016	0.534AsnTyr: 0.534 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	7.181ProAla: 7.181 ± 0.107	0.324ProCys: 0.324 ± 0.014	3.875ProAsp: 3.875 ± 0.057	3.938ProGlu: 3.938 ± 0.06	2.023ProPhe: 2.023 ± 0.043	4.782ProGly: 4.782 ± 0.071	1.022ProHis: 1.022 ± 0.027	2.37ProIle: 2.37 ± 0.046	2.003ProLys: 2.003 ± 0.041	4.776ProLeu: 4.776 ± 0.061	1.055ProMet: 1.055 ± 0.025	1.298ProAsn: 1.298 ± 0.031	3.073ProPro: 3.073 ± 0.065	1.52ProGln: 1.52 ± 0.04	3.509ProArg: 3.509 ± 0.062	3.072ProSer: 3.072 ± 0.052	2.656ProThr: 2.656 ± 0.051	4.024ProVal: 4.024 ± 0.054	0.7ProTrp: 0.7 ± 0.023	1.119ProTyr: 1.119 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.643GlnAla: 3.643 ± 0.067	0.174GlnCys: 0.174 ± 0.012	1.29GlnAsp: 1.29 ± 0.03	1.243GlnGlu: 1.243 ± 0.033	0.932GlnPhe: 0.932 ± 0.028	2.165GlnGly: 2.165 ± 0.038	0.463GlnHis: 0.463 ± 0.02	1.563GlnIle: 1.563 ± 0.037	0.905GlnLys: 0.905 ± 0.031	2.305GlnLeu: 2.305 ± 0.046	0.655GlnMet: 0.655 ± 0.024	0.718GlnAsn: 0.718 ± 0.024	1.541GlnPro: 1.541 ± 0.037	0.836GlnGln: 0.836 ± 0.034	2.035GlnArg: 2.035 ± 0.04	1.534GlnSer: 1.534 ± 0.031	1.464GlnThr: 1.464 ± 0.034	1.861GlnVal: 1.861 ± 0.034	0.302GlnTrp: 0.302 ± 0.015	0.451GlnTyr: 0.451 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	9.922ArgAla: 9.922 ± 0.102	0.545ArgCys: 0.545 ± 0.022	4.533ArgAsp: 4.533 ± 0.061	4.746ArgGlu: 4.746 ± 0.059	3.125ArgPhe: 3.125 ± 0.049	5.769ArgGly: 5.769 ± 0.067	1.603ArgHis: 1.603 ± 0.034	3.879ArgIle: 3.879 ± 0.057	2.273ArgLys: 2.273 ± 0.048	8.923ArgLeu: 8.923 ± 0.095	1.828ArgMet: 1.828 ± 0.036	1.629ArgAsn: 1.629 ± 0.039	4.547ArgPro: 4.547 ± 0.077	2.161ArgGln: 2.161 ± 0.044	7.49ArgArg: 7.49 ± 0.115	4.278ArgSer: 4.278 ± 0.061	3.521ArgThr: 3.521 ± 0.056	5.461ArgVal: 5.461 ± 0.064	1.086ArgTrp: 1.086 ± 0.028	1.593ArgTyr: 1.593 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	6.72SerAla: 6.72 ± 0.084	0.397SerCys: 0.397 ± 0.019	2.995SerAsp: 2.995 ± 0.057	2.793SerGlu: 2.793 ± 0.046	2.175SerPhe: 2.175 ± 0.039	5.591SerGly: 5.591 ± 0.083	0.931SerHis: 0.931 ± 0.022	2.427SerIle: 2.427 ± 0.049	1.561SerLys: 1.561 ± 0.04	5.063SerLeu: 5.063 ± 0.071	1.116SerMet: 1.116 ± 0.031	1.145SerAsn: 1.145 ± 0.031	3.0SerPro: 3.0 ± 0.048	1.389SerGln: 1.389 ± 0.035	3.98SerArg: 3.98 ± 0.053	2.896SerSer: 2.896 ± 0.057	2.416SerThr: 2.416 ± 0.048	3.818SerVal: 3.818 ± 0.056	0.681SerTrp: 0.681 ± 0.025	1.168SerTyr: 1.168 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	5.955ThrAla: 5.955 ± 0.075	0.385ThrCys: 0.385 ± 0.018	2.524ThrAsp: 2.524 ± 0.039	2.484ThrGlu: 2.484 ± 0.044	1.929ThrPhe: 1.929 ± 0.04	4.775ThrGly: 4.775 ± 0.067	0.858ThrHis: 0.858 ± 0.026	2.575ThrIle: 2.575 ± 0.046	1.307ThrLys: 1.307 ± 0.033	5.704ThrLeu: 5.704 ± 0.072	0.93ThrMet: 0.93 ± 0.028	1.053ThrAsn: 1.053 ± 0.03	3.327ThrPro: 3.327 ± 0.057	1.124ThrGln: 1.124 ± 0.03	3.308ThrArg: 3.308 ± 0.051	2.569ThrSer: 2.569 ± 0.049	2.452ThrThr: 2.452 ± 0.05	4.135ThrVal: 4.135 ± 0.054	0.562ThrTrp: 0.562 ± 0.022	1.008ThrTyr: 1.008 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	11.364ValAla: 11.364 ± 0.108	0.635ValCys: 0.635 ± 0.022	4.764ValAsp: 4.764 ± 0.056	5.314ValGlu: 5.314 ± 0.07	2.786ValPhe: 2.786 ± 0.048	6.419ValGly: 6.419 ± 0.074	1.25ValHis: 1.25 ± 0.034	3.415ValIle: 3.415 ± 0.053	2.418ValLys: 2.418 ± 0.049	6.896ValLeu: 6.896 ± 0.086	1.714ValMet: 1.714 ± 0.037	1.754ValAsn: 1.754 ± 0.041	3.326ValPro: 3.326 ± 0.054	1.768ValGln: 1.768 ± 0.043	5.6ValArg: 5.6 ± 0.065	4.371ValSer: 4.371 ± 0.057	4.697ValThr: 4.697 ± 0.065	6.849ValVal: 6.849 ± 0.087	0.993ValTrp: 0.993 ± 0.027	1.476ValTyr: 1.476 ± 0.031	0.001ValXaa: 0.001 ± 0.001
Trp	1.327TrpAla: 1.327 ± 0.03	0.115TrpCys: 0.115 ± 0.009	0.604TrpAsp: 0.604 ± 0.019	0.543TrpGlu: 0.543 ± 0.02	0.519TrpPhe: 0.519 ± 0.019	0.861TrpGly: 0.861 ± 0.026	0.237TrpHis: 0.237 ± 0.013	0.635TrpIle: 0.635 ± 0.024	0.411TrpLys: 0.411 ± 0.017	1.52TrpLeu: 1.52 ± 0.037	0.314TrpMet: 0.314 ± 0.016	0.367TrpAsn: 0.367 ± 0.019	0.71TrpPro: 0.71 ± 0.027	0.36TrpGln: 0.36 ± 0.018	1.409TrpArg: 1.409 ± 0.034	0.888TrpSer: 0.888 ± 0.028	0.828TrpThr: 0.828 ± 0.026	0.734TrpVal: 0.734 ± 0.026	0.213TrpTrp: 0.213 ± 0.013	0.223TrpTyr: 0.223 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.483TyrAla: 2.483 ± 0.04	0.198TyrCys: 0.198 ± 0.012	1.414TyrAsp: 1.414 ± 0.037	1.285TyrGlu: 1.285 ± 0.035	0.824TyrPhe: 0.824 ± 0.023	2.041TyrGly: 2.041 ± 0.041	0.359TyrHis: 0.359 ± 0.016	0.574TyrIle: 0.574 ± 0.021	0.549TyrLys: 0.549 ± 0.023	2.019TyrLeu: 2.019 ± 0.047	0.35TyrMet: 0.35 ± 0.019	0.457TyrAsn: 0.457 ± 0.02	0.949TyrPro: 0.949 ± 0.031	0.557TyrGln: 0.557 ± 0.019	1.667TyrArg: 1.667 ± 0.036	0.959TyrSer: 0.959 ± 0.028	0.752TyrThr: 0.752 ± 0.021	1.728TyrVal: 1.728 ± 0.035	0.336TyrTrp: 0.336 ± 0.019	0.462TyrTyr: 0.462 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.001	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 4190 proteins (1307744 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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