Sindbis virus (SINV)

Taxonomy: Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes; Martellivirales; Togaviridae; Alphavirus

Average proteome isoelectric point is 7.87

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

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* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>sp|P0DOK0|POLSF_SINDV Frameshifted structural polyprotein OS=Sindbis virus OX=11034 PE=1 SV=1
MM1 pKa = 7.72EE2 pKa = 5.16KK3 pKa = 10.36PVVNVDD9 pKa = 3.55VDD11 pKa = 3.8PQSPFVVQLQKK22 pKa = 10.91SFPQFEE28 pKa = 4.3VVAQQVTPNDD38 pKa = 3.7HH39 pKa = 6.5ANARR43 pKa = 11.84AFSHH47 pKa = 6.73LASKK51 pKa = 10.66LIEE54 pKa = 4.34LEE56 pKa = 4.24VPTTATILDD65 pKa = 3.91IGSAPARR72 pKa = 11.84RR73 pKa = 11.84MFSEE77 pKa = 3.95HH78 pKa = 6.48QYY80 pKa = 11.0HH81 pKa = 6.21CVCPMRR87 pKa = 11.84SPEE90 pKa = 4.49DD91 pKa = 3.74PDD93 pKa = 5.82RR94 pKa = 11.84MMKK97 pKa = 10.19YY98 pKa = 10.39ASKK101 pKa = 10.39LAEE104 pKa = 4.27KK105 pKa = 10.33ACKK108 pKa = 8.53ITNKK112 pKa = 9.95NLHH115 pKa = 6.16EE116 pKa = 4.92KK117 pKa = 10.31IKK119 pKa = 10.52DD120 pKa = 3.38LRR122 pKa = 11.84TVLDD126 pKa = 3.86TPDD129 pKa = 4.09AEE131 pKa = 4.61TPSLCFHH138 pKa = 7.15NDD140 pKa = 2.81VTCNMRR146 pKa = 11.84AEE148 pKa = 4.15YY149 pKa = 10.86SVMQDD154 pKa = 2.8VYY156 pKa = 11.01INAPGTIYY164 pKa = 9.96HH165 pKa = 5.99QAMKK169 pKa = 10.47GVRR172 pKa = 11.84TLYY175 pKa = 10.12WIGFDD180 pKa = 3.11TTQFMFSAMAGSYY193 pKa = 9.07PAYY196 pKa = 7.79NTNWADD202 pKa = 3.65EE203 pKa = 4.37KK204 pKa = 11.35VLEE207 pKa = 4.32ARR209 pKa = 11.84NIGLCSTKK217 pKa = 10.36LSEE220 pKa = 4.29GRR222 pKa = 11.84TGKK225 pKa = 10.54LSIMRR230 pKa = 11.84KK231 pKa = 9.41KK232 pKa = 9.84EE233 pKa = 3.98LKK235 pKa = 9.75PGSRR239 pKa = 11.84VYY241 pKa = 10.45FSVGSTLYY249 pKa = 9.65PEE251 pKa = 5.07HH252 pKa = 6.99RR253 pKa = 11.84ASLQSWHH260 pKa = 6.65LPSVFHH266 pKa = 7.13LNGKK270 pKa = 8.35QSYY273 pKa = 7.41TCRR276 pKa = 11.84CDD278 pKa = 3.42TVVSCEE284 pKa = 4.1GYY286 pKa = 9.01VVKK289 pKa = 10.66KK290 pKa = 9.12ITISPGITGEE300 pKa = 4.34TVGYY304 pKa = 10.42AVTHH308 pKa = 5.8NSEE311 pKa = 4.17GFLLCKK317 pKa = 9.9VTDD320 pKa = 3.8TVKK323 pKa = 10.81GEE325 pKa = 3.94RR326 pKa = 11.84VSFPVCTYY334 pKa = 10.44IPATICDD341 pKa = 3.64QMTGIMATDD350 pKa = 3.97ISPDD354 pKa = 3.64DD355 pKa = 3.87AQKK358 pKa = 11.47LLVGLNQRR366 pKa = 11.84IVINGRR372 pKa = 11.84TNRR375 pKa = 11.84NTNTMQNYY383 pKa = 9.03LLPIIAQGFSKK394 pKa = 9.89WAKK397 pKa = 8.56EE398 pKa = 4.29RR399 pKa = 11.84KK400 pKa = 9.48DD401 pKa = 4.09DD402 pKa = 4.78LDD404 pKa = 3.76NEE406 pKa = 4.34KK407 pKa = 10.09MLGTRR412 pKa = 11.84EE413 pKa = 3.8RR414 pKa = 11.84KK415 pKa = 8.18LTYY418 pKa = 9.51GCLWAFRR425 pKa = 11.84TKK427 pKa = 10.08KK428 pKa = 9.33VHH430 pKa = 5.82SFYY433 pKa = 10.65RR434 pKa = 11.84PPGTQTCVKK443 pKa = 9.98VPASFSAFPMSSVWTTSLPMSLRR466 pKa = 11.84QKK468 pKa = 10.76LKK470 pKa = 10.79LALQPKK476 pKa = 9.77KK477 pKa = 10.25EE478 pKa = 4.05EE479 pKa = 4.11KK480 pKa = 10.22LLQVSEE486 pKa = 4.32EE487 pKa = 4.12LVMEE491 pKa = 4.99AKK493 pKa = 10.43AAFEE497 pKa = 4.28DD498 pKa = 3.98AQEE501 pKa = 3.89EE502 pKa = 4.09ARR504 pKa = 11.84AEE506 pKa = 4.22KK507 pKa = 10.42LRR509 pKa = 11.84EE510 pKa = 4.04ALPPLVADD518 pKa = 4.49KK519 pKa = 11.06GIEE522 pKa = 3.72AAAEE526 pKa = 4.38VVCEE530 pKa = 4.13VEE532 pKa = 5.49GLQADD537 pKa = 3.74IGAALVEE544 pKa = 4.59TPRR547 pKa = 11.84GHH549 pKa = 6.52VRR551 pKa = 11.84IIPQANDD558 pKa = 3.06RR559 pKa = 11.84MIGQYY564 pKa = 10.1IVVSPNSVLKK574 pKa = 10.23NAKK577 pKa = 9.25LAPAHH582 pKa = 6.41PLADD586 pKa = 3.27QVKK589 pKa = 8.92IITHH593 pKa = 5.45SGRR596 pKa = 11.84SGRR599 pKa = 11.84YY600 pKa = 8.54AVEE603 pKa = 4.49PYY605 pKa = 9.73DD606 pKa = 4.86AKK608 pKa = 11.48VLMPAGGAVPWPEE621 pKa = 3.62FLALSEE627 pKa = 4.41SATLVYY633 pKa = 10.62NEE635 pKa = 4.48RR636 pKa = 11.84EE637 pKa = 3.96FVNRR641 pKa = 11.84KK642 pKa = 8.8LYY644 pKa = 10.23HH645 pKa = 6.21IAMHH649 pKa = 6.59GPAKK653 pKa = 9.7NTEE656 pKa = 3.82EE657 pKa = 4.03EE658 pKa = 4.36QYY660 pKa = 11.29KK661 pKa = 7.93VTKK664 pKa = 10.78AEE666 pKa = 4.01LAEE669 pKa = 4.08TEE671 pKa = 4.47YY672 pKa = 11.54VFDD675 pKa = 3.78VDD677 pKa = 5.55KK678 pKa = 11.05KK679 pKa = 9.27RR680 pKa = 11.84CVKK683 pKa = 10.56KK684 pKa = 10.72EE685 pKa = 3.86EE686 pKa = 3.97ASGLVLSGEE695 pKa = 4.33LTNPPYY701 pKa = 10.61HH702 pKa = 6.54EE703 pKa = 4.86LALEE707 pKa = 4.2GLKK710 pKa = 9.13TRR712 pKa = 11.84PAVPYY717 pKa = 9.35KK718 pKa = 10.69VEE720 pKa = 4.32TIGVIGTPGSGKK732 pKa = 10.05SAIIKK737 pKa = 8.3STVTARR743 pKa = 11.84DD744 pKa = 3.39LVTSGKK750 pKa = 10.09KK751 pKa = 9.07EE752 pKa = 3.66NCRR755 pKa = 11.84EE756 pKa = 3.69IEE758 pKa = 3.95ADD760 pKa = 3.68VLRR763 pKa = 11.84LRR765 pKa = 11.84GMQITSKK772 pKa = 9.67TVDD775 pKa = 2.95SVMLNGCHH783 pKa = 6.7KK784 pKa = 10.35AVEE787 pKa = 4.07VLYY790 pKa = 10.82VDD792 pKa = 4.26EE793 pKa = 6.01AFACHH798 pKa = 6.59AGALLALIAIVRR810 pKa = 11.84PRR812 pKa = 11.84KK813 pKa = 9.81KK814 pKa = 10.5VVLCGDD820 pKa = 4.14PMQCGFFNMMQLKK833 pKa = 9.36VHH835 pKa = 6.75FNHH838 pKa = 7.25PEE840 pKa = 3.53KK841 pKa = 10.89DD842 pKa = 3.03ICTKK846 pKa = 10.02TFYY849 pKa = 10.72KK850 pKa = 10.43YY851 pKa = 10.16ISRR854 pKa = 11.84RR855 pKa = 11.84CTQPVTAIVSTLHH868 pKa = 6.52YY869 pKa = 9.5DD870 pKa = 3.82GKK872 pKa = 10.63MKK874 pKa = 8.36TTNPCKK880 pKa = 10.42KK881 pKa = 10.09NIEE884 pKa = 3.9IDD886 pKa = 2.98ITGATKK892 pKa = 10.11PKK894 pKa = 9.82PGDD897 pKa = 3.67IILTCFRR904 pKa = 11.84GWVKK908 pKa = 10.14QLQIDD913 pKa = 4.35YY914 pKa = 9.37PGHH917 pKa = 5.77EE918 pKa = 4.85VMTAAASQGLTRR930 pKa = 11.84KK931 pKa = 9.35GVYY934 pKa = 9.7AVRR937 pKa = 11.84QKK939 pKa = 11.2VNEE942 pKa = 4.06NPLYY946 pKa = 10.62AITSEE951 pKa = 4.24HH952 pKa = 6.19VNVLLTRR959 pKa = 11.84TEE961 pKa = 4.6DD962 pKa = 3.39RR963 pKa = 11.84LVWKK967 pKa = 8.2TLQGDD972 pKa = 3.71PWIKK976 pKa = 10.53QPTNIPKK983 pKa = 10.69GNFQATIEE991 pKa = 4.09DD992 pKa = 3.85WEE994 pKa = 4.59AEE996 pKa = 4.19HH997 pKa = 6.96KK998 pKa = 11.01GIIAAINSPTPRR1010 pKa = 11.84ANPFSCKK1017 pKa = 10.06TNVCWAKK1024 pKa = 10.71ALEE1027 pKa = 5.15PILATAGIVLTGCQWSEE1044 pKa = 4.4LFPQFADD1051 pKa = 4.35DD1052 pKa = 4.58KK1053 pKa = 9.14PHH1055 pKa = 5.84SAIYY1059 pKa = 10.33ALDD1062 pKa = 3.91VICIKK1067 pKa = 10.62FFGMDD1072 pKa = 3.43LTSGLFSKK1080 pKa = 10.7QSIPLTYY1087 pKa = 10.3HH1088 pKa = 6.7PADD1091 pKa = 3.37SARR1094 pKa = 11.84PVAHH1098 pKa = 7.49WDD1100 pKa = 3.38NSPGTRR1106 pKa = 11.84KK1107 pKa = 10.03YY1108 pKa = 10.95GYY1110 pKa = 9.51DD1111 pKa = 3.12HH1112 pKa = 7.55AIAAEE1117 pKa = 4.23LSRR1120 pKa = 11.84RR1121 pKa = 11.84FPVFQLAGKK1130 pKa = 7.91GTQLDD1135 pKa = 4.21LQTGRR1140 pKa = 11.84TRR1142 pKa = 11.84VISAQHH1148 pKa = 5.9NLVPVNRR1155 pKa = 11.84NLPHH1159 pKa = 6.94ALVPEE1164 pKa = 4.41YY1165 pKa = 10.49KK1166 pKa = 9.69EE1167 pKa = 4.07KK1168 pKa = 10.98QPGPVKK1174 pKa = 10.63KK1175 pKa = 10.32FLNQFKK1181 pKa = 9.21HH1182 pKa = 6.1HH1183 pKa = 6.29SVLVVSEE1190 pKa = 4.4EE1191 pKa = 4.15KK1192 pKa = 10.41IEE1194 pKa = 4.1APRR1197 pKa = 11.84KK1198 pKa = 8.24RR1199 pKa = 11.84IEE1201 pKa = 4.0WIAPIGIAGADD1212 pKa = 3.4KK1213 pKa = 10.9NYY1215 pKa = 10.65NLAFGFPPQARR1226 pKa = 11.84YY1227 pKa = 10.33DD1228 pKa = 3.63LVFINIGTKK1237 pKa = 9.66YY1238 pKa = 9.97RR1239 pKa = 11.84NHH1241 pKa = 7.09HH1242 pKa = 5.45FQQCEE1247 pKa = 3.68DD1248 pKa = 3.39HH1249 pKa = 6.9AATLKK1254 pKa = 9.72TLSRR1258 pKa = 11.84SALNCLNPGGTLVVKK1273 pKa = 10.44SYY1275 pKa = 10.95GYY1277 pKa = 11.13ADD1279 pKa = 4.14RR1280 pKa = 11.84NSEE1283 pKa = 4.28DD1284 pKa = 3.42VVTALARR1291 pKa = 11.84KK1292 pKa = 8.52FVRR1295 pKa = 11.84VSAARR1300 pKa = 11.84PDD1302 pKa = 3.96CVSSNTEE1309 pKa = 3.41MYY1311 pKa = 10.76LIFRR1315 pKa = 11.84QLDD1318 pKa = 3.41NSRR1321 pKa = 11.84TRR1323 pKa = 11.84QFTPHH1328 pKa = 6.98HH1329 pKa = 6.37LNCVISSVYY1338 pKa = 10.22EE1339 pKa = 3.92GTRR1342 pKa = 11.84DD1343 pKa = 3.54GVGAAPSYY1351 pKa = 8.36RR1352 pKa = 11.84TKK1354 pKa = 10.76RR1355 pKa = 11.84EE1356 pKa = 3.94NIADD1360 pKa = 3.98CQEE1363 pKa = 4.05EE1364 pKa = 4.52AVVNAANPLGRR1375 pKa = 11.84PGEE1378 pKa = 4.44GVCRR1382 pKa = 11.84AIYY1385 pKa = 9.8KK1386 pKa = 9.88RR1387 pKa = 11.84WPTSFTDD1394 pKa = 3.33SATEE1398 pKa = 3.83TGTARR1403 pKa = 11.84MTVCLGKK1410 pKa = 10.46KK1411 pKa = 9.27VIHH1414 pKa = 6.45AVGPDD1419 pKa = 3.7FRR1421 pKa = 11.84KK1422 pKa = 10.32HH1423 pKa = 5.96PEE1425 pKa = 3.8AEE1427 pKa = 4.05ALKK1430 pKa = 10.2LLQNAYY1436 pKa = 10.01HH1437 pKa = 6.82AVADD1441 pKa = 4.48LVNEE1445 pKa = 4.15HH1446 pKa = 6.65NIKK1449 pKa = 10.49SVAIPLLSTGIYY1461 pKa = 10.22AAGKK1465 pKa = 9.98DD1466 pKa = 3.53RR1467 pKa = 11.84LEE1469 pKa = 4.05VSLNCLTTALDD1480 pKa = 3.58RR1481 pKa = 11.84TDD1483 pKa = 4.1ADD1485 pKa = 3.64VTIYY1489 pKa = 11.03CLDD1492 pKa = 3.86KK1493 pKa = 10.56KK1494 pKa = 9.83WKK1496 pKa = 9.61EE1497 pKa = 4.13RR1498 pKa = 11.84IDD1500 pKa = 3.42AALQLKK1506 pKa = 10.37EE1507 pKa = 4.51SVTEE1511 pKa = 4.6LKK1513 pKa = 11.03DD1514 pKa = 3.18EE1515 pKa = 4.59DD1516 pKa = 4.09MEE1518 pKa = 6.49IDD1520 pKa = 5.44DD1521 pKa = 4.45EE1522 pKa = 4.75LVWIHH1527 pKa = 7.19PDD1529 pKa = 2.88SCLKK1533 pKa = 9.98GRR1535 pKa = 11.84KK1536 pKa = 9.11GFSTTKK1542 pKa = 10.27GKK1544 pKa = 10.53LYY1546 pKa = 10.7SYY1548 pKa = 11.16FEE1550 pKa = 4.15GTKK1553 pKa = 9.96FHH1555 pKa = 6.59QAAKK1559 pKa = 10.7DD1560 pKa = 3.37MAEE1563 pKa = 4.0IKK1565 pKa = 10.77VLFPNDD1571 pKa = 3.44QEE1573 pKa = 5.34SNEE1576 pKa = 3.92QLCAYY1581 pKa = 9.59ILGEE1585 pKa = 3.91TMEE1588 pKa = 5.58AIRR1591 pKa = 11.84EE1592 pKa = 4.1KK1593 pKa = 11.05CPVDD1597 pKa = 3.88HH1598 pKa = 6.91NPSSSPPKK1606 pKa = 9.68TLPCLCMYY1614 pKa = 11.25AMTPEE1619 pKa = 4.05RR1620 pKa = 11.84VHH1622 pKa = 7.02RR1623 pKa = 11.84LRR1625 pKa = 11.84SNNVKK1630 pKa = 10.08EE1631 pKa = 4.17VTVCSSTPLPKK1642 pKa = 10.38HH1643 pKa = 6.32KK1644 pKa = 10.06IKK1646 pKa = 10.75NVQKK1650 pKa = 8.68VQCTKK1655 pKa = 10.13VVLFNPHH1662 pKa = 5.41TPAFVPARR1670 pKa = 11.84KK1671 pKa = 9.71YY1672 pKa = 10.7IEE1674 pKa = 4.72VPEE1677 pKa = 4.26QPTAPPAQAEE1687 pKa = 4.16EE1688 pKa = 4.2APEE1691 pKa = 4.32VVATPSPSTADD1702 pKa = 3.38NTSLDD1707 pKa = 3.67VTDD1710 pKa = 5.01ISLDD1714 pKa = 3.44MDD1716 pKa = 4.39DD1717 pKa = 4.72SSEE1720 pKa = 4.08GSLFSSFSGSDD1731 pKa = 3.42NSITSMDD1738 pKa = 3.49SWSSGPSSLEE1748 pKa = 3.56IVDD1751 pKa = 3.61RR1752 pKa = 11.84RR1753 pKa = 11.84QVVVADD1759 pKa = 3.57VHH1761 pKa = 6.74AVQEE1765 pKa = 4.32PAPIPPPRR1773 pKa = 11.84LKK1775 pKa = 10.85KK1776 pKa = 9.49MARR1779 pKa = 11.84LAAARR1784 pKa = 11.84KK1785 pKa = 9.17EE1786 pKa = 4.19PTPPASNSSEE1796 pKa = 4.07SLHH1799 pKa = 7.19LSFGGVSMSLGSIFDD1814 pKa = 4.01GEE1816 pKa = 4.52TARR1819 pKa = 11.84QAAVQPLATGPTDD1832 pKa = 3.19VPMSFGSFSDD1842 pKa = 4.12GEE1844 pKa = 3.92IDD1846 pKa = 3.47EE1847 pKa = 4.44LSRR1850 pKa = 11.84RR1851 pKa = 11.84VTEE1854 pKa = 4.1SEE1856 pKa = 3.87PVLFGSFEE1864 pKa = 4.34PGEE1867 pKa = 4.24VNSIISSRR1875 pKa = 11.84SAVSFPLRR1883 pKa = 11.84KK1884 pKa = 8.62QRR1886 pKa = 11.84RR1887 pKa = 11.84RR1888 pKa = 11.84RR1889 pKa = 11.84RR1890 pKa = 11.84SRR1892 pKa = 11.84RR1893 pKa = 11.84TEE1895 pKa = 3.58YY1896 pKa = 10.15XLTGVGGYY1904 pKa = 9.52IFSTDD1909 pKa = 3.24TGPGHH1914 pKa = 6.02LQKK1917 pKa = 10.91KK1918 pKa = 9.82SVLQNQLTEE1927 pKa = 4.08PTLEE1931 pKa = 4.02RR1932 pKa = 11.84NVLEE1936 pKa = 5.15RR1937 pKa = 11.84IHH1939 pKa = 7.66APVLDD1944 pKa = 3.97TSKK1947 pKa = 11.23EE1948 pKa = 3.98EE1949 pKa = 4.01QLKK1952 pKa = 10.47LRR1954 pKa = 11.84YY1955 pKa = 10.32QMMPTEE1961 pKa = 4.57ANKK1964 pKa = 10.19SRR1966 pKa = 11.84YY1967 pKa = 7.24QSRR1970 pKa = 11.84KK1971 pKa = 9.46VEE1973 pKa = 3.98NQKK1976 pKa = 11.15AITTEE1981 pKa = 3.91RR1982 pKa = 11.84LLSGLRR1988 pKa = 11.84LYY1990 pKa = 11.18NSATDD1995 pKa = 3.43QPEE1998 pKa = 4.59CYY2000 pKa = 9.98KK2001 pKa = 9.58ITYY2004 pKa = 7.4PKK2006 pKa = 9.58PLYY2009 pKa = 10.33SSSVPANYY2017 pKa = 9.96SDD2019 pKa = 3.61PQFAVAVCNNYY2030 pKa = 9.82LHH2032 pKa = 6.84EE2033 pKa = 4.96NYY2035 pKa = 7.51PTVASYY2041 pKa = 10.99QITDD2045 pKa = 3.64EE2046 pKa = 4.04YY2047 pKa = 11.39DD2048 pKa = 3.05AYY2050 pKa = 11.62LDD2052 pKa = 3.85MVDD2055 pKa = 3.95GTVACLDD2062 pKa = 3.67TATFCPAKK2070 pKa = 10.32LRR2072 pKa = 11.84SYY2074 pKa = 9.7PKK2076 pKa = 8.49KK2077 pKa = 10.08HH2078 pKa = 6.51EE2079 pKa = 3.83YY2080 pKa = 9.47RR2081 pKa = 11.84APNIRR2086 pKa = 11.84SAVPSAMQNTLQNVLIAATKK2106 pKa = 9.7RR2107 pKa = 11.84NCNVTQMRR2115 pKa = 11.84EE2116 pKa = 4.06LPTLDD2121 pKa = 3.17SATFNVEE2128 pKa = 3.75CFRR2131 pKa = 11.84KK2132 pKa = 9.61YY2133 pKa = 10.96ACNDD2137 pKa = 3.43EE2138 pKa = 4.2YY2139 pKa = 10.86WEE2141 pKa = 4.14EE2142 pKa = 4.25FARR2145 pKa = 11.84KK2146 pKa = 8.73PIRR2149 pKa = 11.84ITTEE2153 pKa = 3.43FVTAYY2158 pKa = 9.55VARR2161 pKa = 11.84LKK2163 pKa = 10.79GPKK2166 pKa = 9.27AAALFAKK2173 pKa = 9.47TYY2175 pKa = 10.9NLVPLQEE2182 pKa = 4.11VPMDD2186 pKa = 4.04RR2187 pKa = 11.84FVMDD2191 pKa = 3.5MKK2193 pKa = 10.69RR2194 pKa = 11.84DD2195 pKa = 3.73VKK2197 pKa = 9.74VTPGTKK2203 pKa = 8.49HH2204 pKa = 4.48TEE2206 pKa = 3.91EE2207 pKa = 4.12RR2208 pKa = 11.84PKK2210 pKa = 10.92VQVIQAAEE2218 pKa = 3.99PLATAYY2224 pKa = 10.83LCGIHH2229 pKa = 6.74RR2230 pKa = 11.84EE2231 pKa = 4.06LVRR2234 pKa = 11.84RR2235 pKa = 11.84LTAVLLPNIHH2245 pKa = 6.28TLFDD2249 pKa = 3.49MSAEE2253 pKa = 4.19DD2254 pKa = 3.72FDD2256 pKa = 6.6AIIAEE2261 pKa = 4.46HH2262 pKa = 6.66FKK2264 pKa = 11.04QGDD2267 pKa = 3.76PVLEE2271 pKa = 3.88TDD2273 pKa = 3.41IASFDD2278 pKa = 3.73KK2279 pKa = 11.41SQDD2282 pKa = 3.16DD2283 pKa = 3.8AMALTGLMILEE2294 pKa = 4.9DD2295 pKa = 4.25LGVDD2299 pKa = 4.08QPLLDD2304 pKa = 5.55LIEE2307 pKa = 4.44CAFGEE2312 pKa = 4.32ISSTHH2317 pKa = 6.38LPTGTRR2323 pKa = 11.84FKK2325 pKa = 10.46FGAMMKK2331 pKa = 10.15SGMFLTLFVNTVLNVVIASRR2351 pKa = 11.84VLEE2354 pKa = 4.11EE2355 pKa = 3.79RR2356 pKa = 11.84LKK2358 pKa = 10.25TSRR2361 pKa = 11.84CAAFIGDD2368 pKa = 4.22DD2369 pKa = 4.09NIIHH2373 pKa = 6.18GVVSDD2378 pKa = 3.71KK2379 pKa = 11.32EE2380 pKa = 4.1MAEE2383 pKa = 4.74RR2384 pKa = 11.84CATWLNMEE2392 pKa = 4.45VKK2394 pKa = 10.3IIDD2397 pKa = 3.63AVIGEE2402 pKa = 4.48RR2403 pKa = 11.84PPYY2406 pKa = 9.78FCGGFILQDD2415 pKa = 3.62SVTSTACRR2423 pKa = 11.84VADD2426 pKa = 3.69PLKK2429 pKa = 10.79RR2430 pKa = 11.84LFKK2433 pKa = 10.56LGKK2436 pKa = 8.8PLPADD2441 pKa = 4.04DD2442 pKa = 4.96EE2443 pKa = 4.26QDD2445 pKa = 3.19EE2446 pKa = 4.23DD2447 pKa = 4.13RR2448 pKa = 11.84RR2449 pKa = 11.84RR2450 pKa = 11.84ALLDD2454 pKa = 3.1EE2455 pKa = 4.28TKK2457 pKa = 10.21AWFRR2461 pKa = 11.84VGITGTLAVAVTTRR2475 pKa = 11.84YY2476 pKa = 9.67EE2477 pKa = 3.96VDD2479 pKa = 3.4NITPVLLALRR2489 pKa = 11.84TFAQSKK2495 pKa = 9.88RR2496 pKa = 11.84AFQAIRR2502 pKa = 11.84GEE2504 pKa = 4.16IKK2506 pKa = 10.33HH2507 pKa = 6.51LYY2509 pKa = 9.61GGPKK2513 pKa = 9.74

Molecular weight:
279.55 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>sp|P0DOK0|POLSF_SINDV Frameshifted structural polyprotein OS=Sindbis virus OX=11034 PE=1 SV=1
MM1 pKa = 7.29NRR3 pKa = 11.84GFFNMLGRR11 pKa = 11.84RR12 pKa = 11.84PFPAPTAMWRR22 pKa = 11.84PRR24 pKa = 11.84RR25 pKa = 11.84RR26 pKa = 11.84RR27 pKa = 11.84QAAPMPARR35 pKa = 11.84NGLASQIQQLTTAVSALVIGQATRR59 pKa = 11.84PQPPRR64 pKa = 11.84PRR66 pKa = 11.84PPPRR70 pKa = 11.84QKK72 pKa = 10.51KK73 pKa = 8.51QAPKK77 pKa = 10.33QPPKK81 pKa = 9.85PKK83 pKa = 10.1KK84 pKa = 10.04PKK86 pKa = 8.26TQEE89 pKa = 3.89KK90 pKa = 10.27KK91 pKa = 10.25KK92 pKa = 10.32KK93 pKa = 9.98QPAKK97 pKa = 9.39PKK99 pKa = 8.21PGKK102 pKa = 8.08RR103 pKa = 11.84QRR105 pKa = 11.84MALKK109 pKa = 10.74LEE111 pKa = 4.2ADD113 pKa = 3.7RR114 pKa = 11.84LFDD117 pKa = 4.42VKK119 pKa = 11.26NEE121 pKa = 4.16DD122 pKa = 3.5GDD124 pKa = 4.49VIGHH128 pKa = 6.77ALAMEE133 pKa = 4.57GKK135 pKa = 9.79VMKK138 pKa = 9.36PLHH141 pKa = 5.77VKK143 pKa = 8.99GTIDD147 pKa = 4.07HH148 pKa = 6.94PVLSKK153 pKa = 11.28LKK155 pKa = 8.22FTKK158 pKa = 10.41SSAYY162 pKa = 10.5DD163 pKa = 3.26MEE165 pKa = 4.75FAQLPVNMRR174 pKa = 11.84SEE176 pKa = 4.3AFTYY180 pKa = 9.92TSEE183 pKa = 4.23HH184 pKa = 6.97PEE186 pKa = 3.86GFYY189 pKa = 10.62NWHH192 pKa = 6.8HH193 pKa = 6.43GAVQYY198 pKa = 11.02SGGRR202 pKa = 11.84FTIPRR207 pKa = 11.84GVGGRR212 pKa = 11.84GDD214 pKa = 3.55SGRR217 pKa = 11.84PIMDD221 pKa = 3.08NSGRR225 pKa = 11.84VVAIVLGGADD235 pKa = 3.5EE236 pKa = 4.5GTRR239 pKa = 11.84TALSVVTWNSKK250 pKa = 9.73GKK252 pKa = 8.43TIKK255 pKa = 7.46TTPEE259 pKa = 3.81GTEE262 pKa = 3.86EE263 pKa = 3.75WSAAPLVTAMCLLGNVSFPCDD284 pKa = 3.82RR285 pKa = 11.84PPTCYY290 pKa = 9.68TRR292 pKa = 11.84EE293 pKa = 3.88PSRR296 pKa = 11.84ALDD299 pKa = 3.26ILEE302 pKa = 4.24EE303 pKa = 4.31NVNHH307 pKa = 6.43EE308 pKa = 5.05AYY310 pKa = 7.87DD311 pKa = 3.74TLLNAILRR319 pKa = 11.84CGSSGRR325 pKa = 11.84SKK327 pKa = 10.8RR328 pKa = 11.84SVIDD332 pKa = 4.41DD333 pKa = 3.76FTLTSPYY340 pKa = 10.6LGTCSYY346 pKa = 10.57CHH348 pKa = 5.93HH349 pKa = 6.83TVPCFSPVKK358 pKa = 10.18IEE360 pKa = 4.08QVWDD364 pKa = 3.52EE365 pKa = 4.67ADD367 pKa = 3.72DD368 pKa = 3.73NTIRR372 pKa = 11.84IQTSAQFGYY381 pKa = 9.75DD382 pKa = 3.22QSGAASANKK391 pKa = 8.57YY392 pKa = 10.55RR393 pKa = 11.84YY394 pKa = 8.77MSLKK398 pKa = 9.67QDD400 pKa = 3.39HH401 pKa = 5.49TVKK404 pKa = 10.51EE405 pKa = 4.27GTMDD409 pKa = 4.86DD410 pKa = 3.74IKK412 pKa = 10.86ISTSGPCRR420 pKa = 11.84RR421 pKa = 11.84LSYY424 pKa = 10.36KK425 pKa = 10.65GYY427 pKa = 10.26FLLAKK432 pKa = 9.5CPPGDD437 pKa = 3.72SVTVSIVSSNSATSCTLARR456 pKa = 11.84KK457 pKa = 9.42IKK459 pKa = 9.12PKK461 pKa = 10.1FVGRR465 pKa = 11.84EE466 pKa = 3.99KK467 pKa = 11.08YY468 pKa = 10.24DD469 pKa = 3.44LPPVHH474 pKa = 6.62GKK476 pKa = 10.26KK477 pKa = 9.83IPCTVYY483 pKa = 10.84DD484 pKa = 3.87RR485 pKa = 11.84LKK487 pKa = 9.51EE488 pKa = 4.17TTAGYY493 pKa = 8.51ITMHH497 pKa = 7.11RR498 pKa = 11.84PRR500 pKa = 11.84PHH502 pKa = 7.23AYY504 pKa = 8.47TSYY507 pKa = 11.03LEE509 pKa = 4.11EE510 pKa = 4.73SSGKK514 pKa = 10.42VYY516 pKa = 10.8AKK518 pKa = 10.26PPSGKK523 pKa = 10.26NITYY527 pKa = 8.85EE528 pKa = 4.52CKK530 pKa = 10.56CGDD533 pKa = 4.03YY534 pKa = 9.56KK535 pKa = 11.0TGTVSTRR542 pKa = 11.84TEE544 pKa = 3.67ITGCTAIKK552 pKa = 10.26QCVAYY557 pKa = 9.88KK558 pKa = 10.25SDD560 pKa = 3.31QTKK563 pKa = 8.75WVFNSPDD570 pKa = 4.07LIRR573 pKa = 11.84HH574 pKa = 6.77DD575 pKa = 4.26DD576 pKa = 3.34HH577 pKa = 6.53TAQGKK582 pKa = 8.54LHH584 pKa = 6.94LPFKK588 pKa = 10.32LIPSTCMVPVAHH600 pKa = 7.04APNVIHH606 pKa = 6.42GFKK609 pKa = 10.4HH610 pKa = 6.41ISLQLDD616 pKa = 3.59TDD618 pKa = 4.03HH619 pKa = 6.9LTLLTTRR626 pKa = 11.84RR627 pKa = 11.84LGANPEE633 pKa = 4.19PTTEE637 pKa = 4.23WIVGKK642 pKa = 7.11TVRR645 pKa = 11.84NFTVDD650 pKa = 3.35RR651 pKa = 11.84DD652 pKa = 3.56GLEE655 pKa = 4.46YY656 pKa = 10.06IWGNHH661 pKa = 4.5EE662 pKa = 3.95PVRR665 pKa = 11.84VYY667 pKa = 10.69AQEE670 pKa = 4.06SAPGDD675 pKa = 3.53PHH677 pKa = 6.83GWPHH681 pKa = 7.28EE682 pKa = 4.31IVQHH686 pKa = 5.6YY687 pKa = 6.7YY688 pKa = 10.03HH689 pKa = 7.27RR690 pKa = 11.84HH691 pKa = 4.77PVYY694 pKa = 10.32TILAVASATVAMMIGVTVAVLCACKK719 pKa = 10.1ARR721 pKa = 11.84RR722 pKa = 11.84EE723 pKa = 4.17CLTPYY728 pKa = 10.97ALAPNAVIPTSLALLCCVRR747 pKa = 11.84SANAEE752 pKa = 4.23TFTEE756 pKa = 4.39TMSYY760 pKa = 10.22LWSNSQPFFWVQLCIPLAAFIVLMRR785 pKa = 11.84CCSCCLPFLSGCRR798 pKa = 11.84RR799 pKa = 11.84LPGEE803 pKa = 3.84GRR805 pKa = 11.84RR806 pKa = 11.84LRR808 pKa = 11.84TCDD811 pKa = 3.39HH812 pKa = 6.82CSKK815 pKa = 10.66CATDD819 pKa = 3.7TVV821 pKa = 3.73

Molecular weight:
91.21 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3

0

3

4579

821

2513

1526.3

169.18

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.539 ± 0.246

2.861 ± 0.401

4.739 ± 0.257

5.482 ± 0.724

3.385 ± 0.132

5.744 ± 0.414

2.795 ± 0.239

4.761 ± 0.155

6.486 ± 0.114

7.6 ± 0.435

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.293 ± 0.018

3.516 ± 0.254

6.836 ± 0.498

3.472 ± 0.08

5.569 ± 0.357

6.748 ± 0.339

7.425 ± 0.338

7.316 ± 0.277

1.048 ± 0.127

3.363 ± 0.161

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski