Amino acid dipepetide frequency for Caballeronia telluris

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
17.063AlaAla: 17.063 ± 0.14
1.341AlaCys: 1.341 ± 0.027
6.662AlaAsp: 6.662 ± 0.062
6.098AlaGlu: 6.098 ± 0.063
4.507AlaPhe: 4.507 ± 0.054
10.15AlaGly: 10.15 ± 0.08
2.837AlaHis: 2.837 ± 0.038
5.975AlaIle: 5.975 ± 0.059
4.21AlaLys: 4.21 ± 0.053
14.397AlaLeu: 14.397 ± 0.11
3.337AlaMet: 3.337 ± 0.04
3.391AlaAsn: 3.391 ± 0.048
5.954AlaPro: 5.954 ± 0.076
4.989AlaGln: 4.989 ± 0.056
9.367AlaArg: 9.367 ± 0.089
7.89AlaSer: 7.89 ± 0.073
6.435AlaThr: 6.435 ± 0.061
8.685AlaVal: 8.685 ± 0.076
1.642AlaTrp: 1.642 ± 0.031
2.704AlaTyr: 2.704 ± 0.037
0.0AlaXaa: 0.0 ± 0.0
Cys
1.253CysAla: 1.253 ± 0.026
0.136CysCys: 0.136 ± 0.008
0.574CysAsp: 0.574 ± 0.02
0.511CysGlu: 0.511 ± 0.016
0.343CysPhe: 0.343 ± 0.014
1.005CysGly: 1.005 ± 0.026
0.254CysHis: 0.254 ± 0.014
0.429CysIle: 0.429 ± 0.017
0.224CysLys: 0.224 ± 0.011
0.765CysLeu: 0.765 ± 0.017
0.206CysMet: 0.206 ± 0.009
0.245CysAsn: 0.245 ± 0.012
0.443CysPro: 0.443 ± 0.016
0.214CysGln: 0.214 ± 0.011
0.632CysArg: 0.632 ± 0.017
0.499CysSer: 0.499 ± 0.016
0.467CysThr: 0.467 ± 0.015
0.793CysVal: 0.793 ± 0.018
0.122CysTrp: 0.122 ± 0.008
0.222CysTyr: 0.222 ± 0.012
0.0CysXaa: 0.0 ± 0.0
Asp
8.156AspAla: 8.156 ± 0.094
0.453AspCys: 0.453 ± 0.016
3.44AspAsp: 3.44 ± 0.046
3.634AspGlu: 3.634 ± 0.045
2.083AspPhe: 2.083 ± 0.03
4.56AspGly: 4.56 ± 0.056
1.168AspHis: 1.168 ± 0.025
2.613AspIle: 2.613 ± 0.044
1.643AspLys: 1.643 ± 0.029
5.215AspLeu: 5.215 ± 0.062
1.187AspMet: 1.187 ± 0.023
1.263AspAsn: 1.263 ± 0.026
3.025AspPro: 3.025 ± 0.044
1.505AspGln: 1.505 ± 0.029
3.487AspArg: 3.487 ± 0.045
2.589AspSer: 2.589 ± 0.04
2.822AspThr: 2.822 ± 0.039
4.446AspVal: 4.446 ± 0.048
0.932AspTrp: 0.932 ± 0.024
1.511AspTyr: 1.511 ± 0.025
0.0AspXaa: 0.0 ± 0.0
Glu
6.773GluAla: 6.773 ± 0.075
0.403GluCys: 0.403 ± 0.014
2.14GluAsp: 2.14 ± 0.031
2.543GluGlu: 2.543 ± 0.046
1.831GluPhe: 1.831 ± 0.028
3.578GluGly: 3.578 ± 0.047
1.437GluHis: 1.437 ± 0.029
2.756GluIle: 2.756 ± 0.041
1.955GluLys: 1.955 ± 0.041
5.376GluLeu: 5.376 ± 0.056
1.218GluMet: 1.218 ± 0.029
1.425GluAsn: 1.425 ± 0.028
2.588GluPro: 2.588 ± 0.037
2.229GluGln: 2.229 ± 0.038
5.2GluArg: 5.2 ± 0.057
2.77GluSer: 2.77 ± 0.043
3.01GluThr: 3.01 ± 0.039
3.413GluVal: 3.413 ± 0.052
0.744GluTrp: 0.744 ± 0.019
1.13GluTyr: 1.13 ± 0.026
0.0GluXaa: 0.0 ± 0.0
Phe
4.86PheAla: 4.86 ± 0.056
0.444PheCys: 0.444 ± 0.016
2.819PheAsp: 2.819 ± 0.038
2.169PheGlu: 2.169 ± 0.034
1.546PhePhe: 1.546 ± 0.034
3.739PheGly: 3.739 ± 0.052
0.743PheHis: 0.743 ± 0.021
1.667PheIle: 1.667 ± 0.03
1.058PheLys: 1.058 ± 0.024
3.057PheLeu: 3.057 ± 0.042
0.785PheMet: 0.785 ± 0.017
1.145PheAsn: 1.145 ± 0.025
1.612PhePro: 1.612 ± 0.03
0.976PheGln: 0.976 ± 0.025
2.008PheArg: 2.008 ± 0.034
2.278PheSer: 2.278 ± 0.031
1.973PheThr: 1.973 ± 0.031
3.208PheVal: 3.208 ± 0.049
0.519PheTrp: 0.519 ± 0.019
0.971PheTyr: 0.971 ± 0.026
0.0PheXaa: 0.0 ± 0.0
Gly
9.522GlyAla: 9.522 ± 0.083
0.845GlyCys: 0.845 ± 0.02
4.009GlyAsp: 4.009 ± 0.048
4.345GlyGlu: 4.345 ± 0.044
3.443GlyPhe: 3.443 ± 0.047
6.699GlyGly: 6.699 ± 0.075
1.884GlyHis: 1.884 ± 0.03
4.354GlyIle: 4.354 ± 0.058
3.171GlyLys: 3.171 ± 0.045
7.736GlyLeu: 7.736 ± 0.065
2.22GlyMet: 2.22 ± 0.034
2.276GlyAsn: 2.276 ± 0.05
2.877GlyPro: 2.877 ± 0.039
2.542GlyGln: 2.542 ± 0.043
5.38GlyArg: 5.38 ± 0.059
4.49GlySer: 4.49 ± 0.054
4.538GlyThr: 4.538 ± 0.062
6.739GlyVal: 6.739 ± 0.063
1.33GlyTrp: 1.33 ± 0.029
2.334GlyTyr: 2.334 ± 0.038
0.0GlyXaa: 0.0 ± 0.0
His
3.052HisAla: 3.052 ± 0.044
0.26HisCys: 0.26 ± 0.011
1.39HisAsp: 1.39 ± 0.025
1.268HisGlu: 1.268 ± 0.029
0.914HisPhe: 0.914 ± 0.023
2.131HisGly: 2.131 ± 0.035
0.652HisHis: 0.652 ± 0.019
0.923HisIle: 0.923 ± 0.022
0.571HisLys: 0.571 ± 0.018
2.127HisLeu: 2.127 ± 0.036
0.502HisMet: 0.502 ± 0.016
0.508HisAsn: 0.508 ± 0.015
1.421HisPro: 1.421 ± 0.027
0.621HisGln: 0.621 ± 0.017
1.557HisArg: 1.557 ± 0.035
1.084HisSer: 1.084 ± 0.021
1.052HisThr: 1.052 ± 0.023
1.714HisVal: 1.714 ± 0.032
0.405HisTrp: 0.405 ± 0.013
0.671HisTyr: 0.671 ± 0.018
0.0HisXaa: 0.0 ± 0.0
Ile
7.286IleAla: 7.286 ± 0.067
0.44IleCys: 0.44 ± 0.015
3.781IleAsp: 3.781 ± 0.05
3.379IleGlu: 3.379 ± 0.048
1.493IlePhe: 1.493 ± 0.031
4.916IleGly: 4.916 ± 0.056
0.922IleHis: 0.922 ± 0.023
1.604IleIle: 1.604 ± 0.031
1.37IleLys: 1.37 ± 0.031
3.417IleLeu: 3.417 ± 0.045
0.757IleMet: 0.757 ± 0.021
1.36IleAsn: 1.36 ± 0.027
2.057IlePro: 2.057 ± 0.04
1.192IleGln: 1.192 ± 0.024
2.797IleArg: 2.797 ± 0.044
2.434IleSer: 2.434 ± 0.035
2.279IleThr: 2.279 ± 0.039
4.604IleVal: 4.604 ± 0.054
0.516IleTrp: 0.516 ± 0.015
1.039IleTyr: 1.039 ± 0.023
0.0IleXaa: 0.0 ± 0.0
Lys
3.683LysAla: 3.683 ± 0.052
0.188LysCys: 0.188 ± 0.01
1.55LysAsp: 1.55 ± 0.032
1.585LysGlu: 1.585 ± 0.033
0.952LysPhe: 0.952 ± 0.026
2.31LysGly: 2.31 ± 0.044
0.791LysHis: 0.791 ± 0.023
1.658LysIle: 1.658 ± 0.032
1.469LysLys: 1.469 ± 0.04
3.494LysLeu: 3.494 ± 0.055
0.861LysMet: 0.861 ± 0.023
0.945LysAsn: 0.945 ± 0.02
2.098LysPro: 2.098 ± 0.033
1.292LysGln: 1.292 ± 0.026
2.593LysArg: 2.593 ± 0.041
2.002LysSer: 2.002 ± 0.033
2.064LysThr: 2.064 ± 0.031
2.37LysVal: 2.37 ± 0.041
0.403LysTrp: 0.403 ± 0.014
0.737LysTyr: 0.737 ± 0.02
0.0LysXaa: 0.0 ± 0.0
Leu
14.013LeuAla: 14.013 ± 0.112
1.024LeuCys: 1.024 ± 0.024
6.154LeuAsp: 6.154 ± 0.057
4.762LeuGlu: 4.762 ± 0.059
3.672LeuPhe: 3.672 ± 0.047
7.925LeuGly: 7.925 ± 0.074
2.202LeuHis: 2.202 ± 0.038
4.727LeuIle: 4.727 ± 0.058
3.538LeuLys: 3.538 ± 0.041
9.687LeuLeu: 9.687 ± 0.093
2.253LeuMet: 2.253 ± 0.038
2.748LeuAsn: 2.748 ± 0.036
5.507LeuPro: 5.507 ± 0.054
3.149LeuGln: 3.149 ± 0.038
6.886LeuArg: 6.886 ± 0.068
6.081LeuSer: 6.081 ± 0.057
5.526LeuThr: 5.526 ± 0.057
7.525LeuVal: 7.525 ± 0.064
1.128LeuTrp: 1.128 ± 0.025
2.143LeuTyr: 2.143 ± 0.034
0.0LeuXaa: 0.0 ± 0.0
Met
2.473MetAla: 2.473 ± 0.039
0.186MetCys: 0.186 ± 0.009
0.924MetAsp: 0.924 ± 0.023
0.955MetGlu: 0.955 ± 0.021
0.782MetPhe: 0.782 ± 0.022
1.52MetGly: 1.52 ± 0.027
0.554MetHis: 0.554 ± 0.014
1.196MetIle: 1.196 ± 0.025
1.116MetLys: 1.116 ± 0.024
2.737MetLeu: 2.737 ± 0.041
0.604MetMet: 0.604 ± 0.019
0.99MetAsn: 0.99 ± 0.021
1.509MetPro: 1.509 ± 0.029
1.021MetGln: 1.021 ± 0.024
1.85MetArg: 1.85 ± 0.03
1.817MetSer: 1.817 ± 0.027
1.692MetThr: 1.692 ± 0.027
1.409MetVal: 1.409 ± 0.03
0.223MetTrp: 0.223 ± 0.01
0.399MetTyr: 0.399 ± 0.013
0.0MetXaa: 0.0 ± 0.0
Asn
3.701AsnAla: 3.701 ± 0.052
0.251AsnCys: 0.251 ± 0.012
1.506AsnAsp: 1.506 ± 0.025
1.397AsnGlu: 1.397 ± 0.028
1.002AsnPhe: 1.002 ± 0.027
2.57AsnGly: 2.57 ± 0.04
0.548AsnHis: 0.548 ± 0.016
1.229AsnIle: 1.229 ± 0.028
0.762AsnLys: 0.762 ± 0.02
2.666AsnLeu: 2.666 ± 0.036
0.549AsnMet: 0.549 ± 0.02
0.815AsnAsn: 0.815 ± 0.021
1.83AsnPro: 1.83 ± 0.035
0.905AsnGln: 0.905 ± 0.023
1.868AsnArg: 1.868 ± 0.035
1.352AsnSer: 1.352 ± 0.027
1.447AsnThr: 1.447 ± 0.037
2.344AsnVal: 2.344 ± 0.04
0.427AsnTrp: 0.427 ± 0.015
0.695AsnTyr: 0.695 ± 0.018
0.0AsnXaa: 0.0 ± 0.0
Pro
6.523ProAla: 6.523 ± 0.078
0.374ProCys: 0.374 ± 0.013
3.263ProAsp: 3.263 ± 0.042
2.962ProGlu: 2.962 ± 0.037
1.98ProPhe: 1.98 ± 0.035
4.097ProGly: 4.097 ± 0.048
1.216ProHis: 1.216 ± 0.027
1.988ProIle: 1.988 ± 0.031
1.618ProLys: 1.618 ± 0.029
5.028ProLeu: 5.028 ± 0.054
1.155ProMet: 1.155 ± 0.026
1.489ProAsn: 1.489 ± 0.029
2.492ProPro: 2.492 ± 0.04
1.792ProGln: 1.792 ± 0.034
2.922ProArg: 2.922 ± 0.04
2.979ProSer: 2.979 ± 0.043
2.484ProThr: 2.484 ± 0.037
4.214ProVal: 4.214 ± 0.046
0.665ProTrp: 0.665 ± 0.017
1.171ProTyr: 1.171 ± 0.024
0.0ProXaa: 0.0 ± 0.0
Gln
4.16GlnAla: 4.16 ± 0.051
0.28GlnCys: 0.28 ± 0.011
1.322GlnAsp: 1.322 ± 0.025
1.362GlnGlu: 1.362 ± 0.027
1.263GlnPhe: 1.263 ± 0.027
2.3GlnGly: 2.3 ± 0.041
0.873GlnHis: 0.873 ± 0.023
1.872GlnIle: 1.872 ± 0.033
1.218GlnLys: 1.218 ± 0.03
3.499GlnLeu: 3.499 ± 0.055
0.992GlnMet: 0.992 ± 0.024
0.913GlnAsn: 0.913 ± 0.023
1.864GlnPro: 1.864 ± 0.035
1.68GlnGln: 1.68 ± 0.04
2.721GlnArg: 2.721 ± 0.038
2.041GlnSer: 2.041 ± 0.036
1.997GlnThr: 1.997 ± 0.035
2.409GlnVal: 2.409 ± 0.034
0.546GlnTrp: 0.546 ± 0.017
0.871GlnTyr: 0.871 ± 0.02
0.0GlnXaa: 0.0 ± 0.0
Arg
8.653ArgAla: 8.653 ± 0.085
0.605ArgCys: 0.605 ± 0.019
4.073ArgAsp: 4.073 ± 0.054
4.453ArgGlu: 4.453 ± 0.055
3.025ArgPhe: 3.025 ± 0.042
4.713ArgGly: 4.713 ± 0.051
1.822ArgHis: 1.822 ± 0.032
3.619ArgIle: 3.619 ± 0.051
2.147ArgLys: 2.147 ± 0.037
7.232ArgLeu: 7.232 ± 0.077
1.876ArgMet: 1.876 ± 0.034
1.907ArgAsn: 1.907 ± 0.03
3.115ArgPro: 3.115 ± 0.042
2.385ArgGln: 2.385 ± 0.03
5.507ArgArg: 5.507 ± 0.066
3.506ArgSer: 3.506 ± 0.047
3.441ArgThr: 3.441 ± 0.05
5.436ArgVal: 5.436 ± 0.053
1.056ArgTrp: 1.056 ± 0.025
1.948ArgTyr: 1.948 ± 0.036
0.0ArgXaa: 0.0 ± 0.0
Ser
7.045SerAla: 7.045 ± 0.07
0.46SerCys: 0.46 ± 0.017
2.934SerAsp: 2.934 ± 0.046
2.671SerGlu: 2.671 ± 0.041
2.225SerPhe: 2.225 ± 0.033
5.312SerGly: 5.312 ± 0.059
1.226SerHis: 1.226 ± 0.024
2.871SerIle: 2.871 ± 0.039
1.821SerLys: 1.821 ± 0.034
5.732SerLeu: 5.732 ± 0.061
1.498SerMet: 1.498 ± 0.023
1.665SerAsn: 1.665 ± 0.029
2.853SerPro: 2.853 ± 0.042
1.852SerGln: 1.852 ± 0.033
3.753SerArg: 3.753 ± 0.044
3.387SerSer: 3.387 ± 0.055
3.24SerThr: 3.24 ± 0.051
4.475SerVal: 4.475 ± 0.047
0.706SerTrp: 0.706 ± 0.017
1.295SerTyr: 1.295 ± 0.029
0.0SerXaa: 0.0 ± 0.0
Thr
5.96ThrAla: 5.96 ± 0.068
0.418ThrCys: 0.418 ± 0.016
2.793ThrAsp: 2.793 ± 0.048
2.331ThrGlu: 2.331 ± 0.034
1.975ThrPhe: 1.975 ± 0.029
4.719ThrGly: 4.719 ± 0.06
1.25ThrHis: 1.25 ± 0.03
2.669ThrIle: 2.669 ± 0.038
1.462ThrLys: 1.462 ± 0.027
6.442ThrLeu: 6.442 ± 0.057
1.255ThrMet: 1.255 ± 0.026
1.424ThrAsn: 1.424 ± 0.031
3.453ThrPro: 3.453 ± 0.046
1.937ThrGln: 1.937 ± 0.039
3.651ThrArg: 3.651 ± 0.045
3.016ThrSer: 3.016 ± 0.052
2.935ThrThr: 2.935 ± 0.05
4.306ThrVal: 4.306 ± 0.05
0.648ThrTrp: 0.648 ± 0.019
1.22ThrTyr: 1.22 ± 0.032
0.0ThrXaa: 0.0 ± 0.0
Val
9.581ValAla: 9.581 ± 0.077
0.834ValCys: 0.834 ± 0.023
4.35ValAsp: 4.35 ± 0.053
4.376ValGlu: 4.376 ± 0.064
2.915ValPhe: 2.915 ± 0.04
5.5ValGly: 5.5 ± 0.069
1.551ValHis: 1.551 ± 0.03
3.882ValIle: 3.882 ± 0.049
2.598ValLys: 2.598 ± 0.038
7.715ValLeu: 7.715 ± 0.073
1.874ValMet: 1.874 ± 0.035
2.26ValAsn: 2.26 ± 0.035
3.883ValPro: 3.883 ± 0.043
2.437ValGln: 2.437 ± 0.033
5.159ValArg: 5.159 ± 0.049
4.707ValSer: 4.707 ± 0.049
4.496ValThr: 4.496 ± 0.056
6.365ValVal: 6.365 ± 0.07
0.965ValTrp: 0.965 ± 0.025
1.724ValTyr: 1.724 ± 0.033
0.0ValXaa: 0.0 ± 0.0
Trp
1.145TrpAla: 1.145 ± 0.028
0.132TrpCys: 0.132 ± 0.008
0.638TrpAsp: 0.638 ± 0.02
0.507TrpGlu: 0.507 ± 0.016
0.582TrpPhe: 0.582 ± 0.017
0.843TrpGly: 0.843 ± 0.022
0.411TrpHis: 0.411 ± 0.017
0.725TrpIle: 0.725 ± 0.02
0.436TrpLys: 0.436 ± 0.015
1.878TrpLeu: 1.878 ± 0.037
0.371TrpMet: 0.371 ± 0.014
0.472TrpAsn: 0.472 ± 0.016
0.643TrpPro: 0.643 ± 0.02
0.635TrpGln: 0.635 ± 0.02
1.22TrpArg: 1.22 ± 0.028
0.794TrpSer: 0.794 ± 0.02
0.748TrpThr: 0.748 ± 0.019
0.883TrpVal: 0.883 ± 0.02
0.221TrpTrp: 0.221 ± 0.012
0.307TrpTyr: 0.307 ± 0.011
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.729TyrAla: 2.729 ± 0.031
0.266TyrCys: 0.266 ± 0.012
1.409TyrAsp: 1.409 ± 0.051
1.209TyrGlu: 1.209 ± 0.025
1.043TyrPhe: 1.043 ± 0.023
2.144TyrGly: 2.144 ± 0.039
0.481TyrHis: 0.481 ± 0.015
0.889TyrIle: 0.889 ± 0.023
0.657TyrLys: 0.657 ± 0.02
2.449TyrLeu: 2.449 ± 0.041
0.456TyrMet: 0.456 ± 0.018
0.623TyrAsn: 0.623 ± 0.018
1.189TyrPro: 1.189 ± 0.024
0.832TyrGln: 0.832 ± 0.022
1.963TyrArg: 1.963 ± 0.033
1.304TyrSer: 1.304 ± 0.026
1.221TyrThr: 1.221 ± 0.029
1.836TyrVal: 1.836 ± 0.032
0.394TyrTrp: 0.394 ± 0.013
0.63TyrTyr: 0.63 ± 0.02
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6225 proteins (1965106 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski