Amino acid dipepetide frequency for Dictyoglomus turgidum (strain DSM 6724 / Z-1310)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	2.405AlaAla: 2.405 ± 0.092	0.436AlaCys: 0.436 ± 0.029	2.113AlaAsp: 2.113 ± 0.063	3.586AlaGlu: 3.586 ± 0.09	2.55AlaPhe: 2.55 ± 0.069	3.771AlaGly: 3.771 ± 0.092	0.904AlaHis: 0.904 ± 0.041	5.269AlaIle: 5.269 ± 0.103	4.672AlaLys: 4.672 ± 0.101	6.553AlaLeu: 6.553 ± 0.123	1.133AlaMet: 1.133 ± 0.043	1.933AlaAsn: 1.933 ± 0.064	1.693AlaPro: 1.693 ± 0.058	1.637AlaGln: 1.637 ± 0.051	2.353AlaArg: 2.353 ± 0.069	2.741AlaSer: 2.741 ± 0.081	2.241AlaThr: 2.241 ± 0.065	3.56AlaVal: 3.56 ± 0.096	0.581AlaTrp: 0.581 ± 0.031	2.09AlaTyr: 2.09 ± 0.065	0.0AlaXaa: 0.0 ± 0.0
Cys	0.385CysAla: 0.385 ± 0.023	0.063CysCys: 0.063 ± 0.011	0.345CysAsp: 0.345 ± 0.025	0.486CysGlu: 0.486 ± 0.033	0.32CysPhe: 0.32 ± 0.025	0.812CysGly: 0.812 ± 0.048	0.17CysHis: 0.17 ± 0.017	0.53CysIle: 0.53 ± 0.032	0.488CysLys: 0.488 ± 0.031	0.502CysLeu: 0.502 ± 0.033	0.126CysMet: 0.126 ± 0.014	0.301CysAsn: 0.301 ± 0.023	0.499CysPro: 0.499 ± 0.041	0.136CysGln: 0.136 ± 0.017	0.301CysArg: 0.301 ± 0.026	0.381CysSer: 0.381 ± 0.025	0.308CysThr: 0.308 ± 0.025	0.408CysVal: 0.408 ± 0.028	0.098CysTrp: 0.098 ± 0.013	0.262CysTyr: 0.262 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	2.167AspAla: 2.167 ± 0.064	0.285AspCys: 0.285 ± 0.024	1.774AspAsp: 1.774 ± 0.064	3.763AspGlu: 3.763 ± 0.091	3.065AspPhe: 3.065 ± 0.085	3.131AspGly: 3.131 ± 0.076	0.663AspHis: 0.663 ± 0.036	5.186AspIle: 5.186 ± 0.094	4.037AspLys: 4.037 ± 0.084	6.017AspLeu: 6.017 ± 0.106	0.985AspMet: 0.985 ± 0.043	1.821AspAsn: 1.821 ± 0.064	2.584AspPro: 2.584 ± 0.072	0.841AspGln: 0.841 ± 0.044	1.887AspArg: 1.887 ± 0.058	2.11AspSer: 2.11 ± 0.067	1.805AspThr: 1.805 ± 0.054	3.248AspVal: 3.248 ± 0.079	0.633AspTrp: 0.633 ± 0.036	2.465AspTyr: 2.465 ± 0.071	0.0AspXaa: 0.0 ± 0.0
Glu	4.298GluAla: 4.298 ± 0.099	0.38GluCys: 0.38 ± 0.027	4.56GluAsp: 4.56 ± 0.1	9.057GluGlu: 9.057 ± 0.186	3.283GluPhe: 3.283 ± 0.08	4.943GluGly: 4.943 ± 0.107	0.873GluHis: 0.873 ± 0.04	9.071GluIle: 9.071 ± 0.146	9.47GluLys: 9.47 ± 0.163	6.911GluLeu: 6.911 ± 0.121	1.746GluMet: 1.746 ± 0.053	4.802GluAsn: 4.802 ± 0.109	1.957GluPro: 1.957 ± 0.065	1.133GluGln: 1.133 ± 0.045	4.446GluArg: 4.446 ± 0.099	3.042GluSer: 3.042 ± 0.065	2.725GluThr: 2.725 ± 0.06	5.841GluVal: 5.841 ± 0.106	0.703GluTrp: 0.703 ± 0.037	2.93GluTyr: 2.93 ± 0.075	0.0GluXaa: 0.0 ± 0.0
Phe	2.409PheAla: 2.409 ± 0.072	0.402PheCys: 0.402 ± 0.029	2.5PheAsp: 2.5 ± 0.078	3.227PheGlu: 3.227 ± 0.067	2.584PhePhe: 2.584 ± 0.089	3.08PheGly: 3.08 ± 0.074	0.71PheHis: 0.71 ± 0.038	4.711PheIle: 4.711 ± 0.113	3.598PheLys: 3.598 ± 0.075	6.318PheLeu: 6.318 ± 0.145	1.065PheMet: 1.065 ± 0.047	2.246PheAsn: 2.246 ± 0.066	2.216PhePro: 2.216 ± 0.066	1.191PheGln: 1.191 ± 0.051	1.779PheArg: 1.779 ± 0.066	3.944PheSer: 3.944 ± 0.106	2.267PheThr: 2.267 ± 0.067	3.257PheVal: 3.257 ± 0.081	0.652PheTrp: 0.652 ± 0.036	2.538PheTyr: 2.538 ± 0.073	0.0PheXaa: 0.0 ± 0.0
Gly	3.71GlyAla: 3.71 ± 0.099	0.638GlyCys: 0.638 ± 0.043	3.208GlyAsp: 3.208 ± 0.085	5.29GlyGlu: 5.29 ± 0.1	3.397GlyPhe: 3.397 ± 0.081	4.781GlyGly: 4.781 ± 0.124	1.011GlyHis: 1.011 ± 0.046	7.056GlyIle: 7.056 ± 0.125	6.021GlyLys: 6.021 ± 0.112	5.736GlyLeu: 5.736 ± 0.105	1.436GlyMet: 1.436 ± 0.047	2.779GlyAsn: 2.779 ± 0.081	1.782GlyPro: 1.782 ± 0.061	1.293GlyGln: 1.293 ± 0.044	3.233GlyArg: 3.233 ± 0.079	3.255GlySer: 3.255 ± 0.089	3.024GlyThr: 3.024 ± 0.077	5.027GlyVal: 5.027 ± 0.118	0.822GlyTrp: 0.822 ± 0.035	3.278GlyTyr: 3.278 ± 0.081	0.0GlyXaa: 0.0 ± 0.0
His	0.735HisAla: 0.735 ± 0.04	0.138HisCys: 0.138 ± 0.015	0.537HisAsp: 0.537 ± 0.036	0.822HisGlu: 0.822 ± 0.039	0.712HisPhe: 0.712 ± 0.036	0.95HisGly: 0.95 ± 0.038	0.317HisHis: 0.317 ± 0.026	1.328HisIle: 1.328 ± 0.042	0.876HisLys: 0.876 ± 0.041	1.455HisLeu: 1.455 ± 0.054	0.297HisMet: 0.297 ± 0.024	0.661HisAsn: 0.661 ± 0.033	0.964HisPro: 0.964 ± 0.046	0.39HisGln: 0.39 ± 0.026	0.659HisArg: 0.659 ± 0.035	0.74HisSer: 0.74 ± 0.039	0.675HisThr: 0.675 ± 0.036	0.761HisVal: 0.761 ± 0.038	0.164HisTrp: 0.164 ± 0.019	0.577HisTyr: 0.577 ± 0.033	0.0HisXaa: 0.0 ± 0.0
Ile	5.435IleAla: 5.435 ± 0.116	0.668IleCys: 0.668 ± 0.035	4.816IleAsp: 4.816 ± 0.092	7.466IleGlu: 7.466 ± 0.134	5.204IlePhe: 5.204 ± 0.113	6.113IleGly: 6.113 ± 0.106	1.237IleHis: 1.237 ± 0.05	8.575IleIle: 8.575 ± 0.144	7.917IleLys: 7.917 ± 0.126	10.962IleLeu: 10.962 ± 0.178	1.67IleMet: 1.67 ± 0.061	4.576IleAsn: 4.576 ± 0.096	4.828IlePro: 4.828 ± 0.09	1.992IleGln: 1.992 ± 0.07	3.831IleArg: 3.831 ± 0.091	6.567IleSer: 6.567 ± 0.125	4.391IleThr: 4.391 ± 0.09	6.059IleVal: 6.059 ± 0.125	0.962IleTrp: 0.962 ± 0.045	4.088IleTyr: 4.088 ± 0.089	0.0IleXaa: 0.0 ± 0.0
Lys	4.331LysAla: 4.331 ± 0.096	0.471LysCys: 0.471 ± 0.034	5.358LysAsp: 5.358 ± 0.114	10.044LysGlu: 10.044 ± 0.188	2.996LysPhe: 2.996 ± 0.082	5.382LysGly: 5.382 ± 0.091	0.855LysHis: 0.855 ± 0.038	9.183LysIle: 9.183 ± 0.165	7.473LysLys: 7.473 ± 0.126	7.167LysLeu: 7.167 ± 0.115	1.66LysMet: 1.66 ± 0.057	5.015LysAsn: 5.015 ± 0.084	2.571LysPro: 2.571 ± 0.076	1.286LysGln: 1.286 ± 0.048	4.27LysArg: 4.27 ± 0.082	3.659LysSer: 3.659 ± 0.084	3.446LysThr: 3.446 ± 0.085	6.294LysVal: 6.294 ± 0.13	0.78LysTrp: 0.78 ± 0.038	3.525LysTyr: 3.525 ± 0.09	0.0LysXaa: 0.0 ± 0.0
Leu	5.578LeuAla: 5.578 ± 0.105	0.651LeuCys: 0.651 ± 0.035	4.768LeuAsp: 4.768 ± 0.097	8.256LeuGlu: 8.256 ± 0.121	4.991LeuPhe: 4.991 ± 0.106	7.334LeuGly: 7.334 ± 0.133	1.293LeuHis: 1.293 ± 0.047	9.524LeuIle: 9.524 ± 0.157	9.598LeuLys: 9.598 ± 0.156	10.394LeuLeu: 10.394 ± 0.154	1.926LeuMet: 1.926 ± 0.058	4.982LeuAsn: 4.982 ± 0.098	4.342LeuPro: 4.342 ± 0.089	2.276LeuGln: 2.276 ± 0.075	5.06LeuArg: 5.06 ± 0.093	7.828LeuSer: 7.828 ± 0.149	4.663LeuThr: 4.663 ± 0.1	5.786LeuVal: 5.786 ± 0.097	1.119LeuTrp: 1.119 ± 0.049	3.895LeuTyr: 3.895 ± 0.096	0.0LeuXaa: 0.0 ± 0.0
Met	1.392MetAla: 1.392 ± 0.049	0.115MetCys: 0.115 ± 0.015	1.032MetAsp: 1.032 ± 0.045	1.816MetGlu: 1.816 ± 0.059	0.742MetPhe: 0.742 ± 0.034	1.587MetGly: 1.587 ± 0.057	0.262MetHis: 0.262 ± 0.019	1.492MetIle: 1.492 ± 0.048	1.859MetLys: 1.859 ± 0.059	1.681MetLeu: 1.681 ± 0.057	0.406MetMet: 0.406 ± 0.023	0.934MetAsn: 0.934 ± 0.039	0.798MetPro: 0.798 ± 0.035	0.434MetGln: 0.434 ± 0.028	1.165MetArg: 1.165 ± 0.048	1.116MetSer: 1.116 ± 0.043	0.764MetThr: 0.764 ± 0.038	1.335MetVal: 1.335 ± 0.046	0.168MetTrp: 0.168 ± 0.015	0.631MetTyr: 0.631 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	2.183AsnAla: 2.183 ± 0.067	0.346AsnCys: 0.346 ± 0.026	1.611AsnAsp: 1.611 ± 0.051	2.57AsnGlu: 2.57 ± 0.074	3.038AsnPhe: 3.038 ± 0.082	2.512AsnGly: 2.512 ± 0.085	0.593AsnHis: 0.593 ± 0.035	5.251AsnIle: 5.251 ± 0.104	3.67AsnLys: 3.67 ± 0.077	6.29AsnLeu: 6.29 ± 0.134	0.962AsnMet: 0.962 ± 0.045	2.309AsnAsn: 2.309 ± 0.077	2.731AsnPro: 2.731 ± 0.085	1.037AsnGln: 1.037 ± 0.045	1.681AsnArg: 1.681 ± 0.044	2.561AsnSer: 2.561 ± 0.074	1.999AsnThr: 1.999 ± 0.062	3.016AsnVal: 3.016 ± 0.082	0.637AsnTrp: 0.637 ± 0.033	2.239AsnTyr: 2.239 ± 0.065	0.0AsnXaa: 0.0 ± 0.0
Pro	1.768ProAla: 1.768 ± 0.052	0.252ProCys: 0.252 ± 0.02	2.024ProAsp: 2.024 ± 0.057	3.687ProGlu: 3.687 ± 0.088	2.206ProPhe: 2.206 ± 0.062	2.468ProGly: 2.468 ± 0.071	0.7ProHis: 0.7 ± 0.034	3.434ProIle: 3.434 ± 0.08	3.094ProLys: 3.094 ± 0.068	4.049ProLeu: 4.049 ± 0.089	0.64ProMet: 0.64 ± 0.03	1.935ProAsn: 1.935 ± 0.056	1.562ProPro: 1.562 ± 0.059	1.315ProGln: 1.315 ± 0.042	1.364ProArg: 1.364 ± 0.055	2.351ProSer: 2.351 ± 0.065	1.975ProThr: 1.975 ± 0.063	2.573ProVal: 2.573 ± 0.069	0.565ProTrp: 0.565 ± 0.033	2.174ProTyr: 2.174 ± 0.07	0.0ProXaa: 0.0 ± 0.0
Gln	1.317GlnAla: 1.317 ± 0.05	0.135GlnCys: 0.135 ± 0.014	1.06GlnAsp: 1.06 ± 0.044	2.057GlnGlu: 2.057 ± 0.061	0.855GlnPhe: 0.855 ± 0.037	1.574GlnGly: 1.574 ± 0.061	0.304GlnHis: 0.304 ± 0.026	2.138GlnIle: 2.138 ± 0.063	2.269GlnLys: 2.269 ± 0.069	1.676GlnLeu: 1.676 ± 0.056	0.427GlnMet: 0.427 ± 0.03	1.286GlnAsn: 1.286 ± 0.047	0.644GlnPro: 0.644 ± 0.037	0.551GlnGln: 0.551 ± 0.045	1.249GlnArg: 1.249 ± 0.052	0.915GlnSer: 0.915 ± 0.045	0.969GlnThr: 0.969 ± 0.046	1.392GlnVal: 1.392 ± 0.053	0.215GlnTrp: 0.215 ± 0.02	0.756GlnTyr: 0.756 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.384ArgAla: 2.384 ± 0.079	0.306ArgCys: 0.306 ± 0.028	2.377ArgAsp: 2.377 ± 0.066	4.66ArgGlu: 4.66 ± 0.106	2.124ArgPhe: 2.124 ± 0.056	2.928ArgGly: 2.928 ± 0.069	0.535ArgHis: 0.535 ± 0.035	4.562ArgIle: 4.562 ± 0.092	3.707ArgLys: 3.707 ± 0.086	4.151ArgLeu: 4.151 ± 0.088	0.969ArgMet: 0.969 ± 0.039	2.138ArgAsn: 2.138 ± 0.065	1.251ArgPro: 1.251 ± 0.049	0.883ArgGln: 0.883 ± 0.044	2.498ArgArg: 2.498 ± 0.078	1.971ArgSer: 1.971 ± 0.061	1.665ArgThr: 1.665 ± 0.057	3.143ArgVal: 3.143 ± 0.065	0.521ArgTrp: 0.521 ± 0.03	1.84ArgTyr: 1.84 ± 0.059	0.0ArgXaa: 0.0 ± 0.0
Ser	2.981SerAla: 2.981 ± 0.07	0.488SerCys: 0.488 ± 0.03	2.44SerAsp: 2.44 ± 0.069	3.659SerGlu: 3.659 ± 0.086	3.796SerPhe: 3.796 ± 0.101	3.937SerGly: 3.937 ± 0.079	0.871SerHis: 0.871 ± 0.04	5.2SerIle: 5.2 ± 0.097	4.282SerLys: 4.282 ± 0.099	6.936SerLeu: 6.936 ± 0.127	1.161SerMet: 1.161 ± 0.042	2.218SerAsn: 2.218 ± 0.067	2.461SerPro: 2.461 ± 0.066	1.581SerGln: 1.581 ± 0.051	1.982SerArg: 1.982 ± 0.06	3.481SerSer: 3.481 ± 0.099	2.41SerThr: 2.41 ± 0.073	2.958SerVal: 2.958 ± 0.076	0.722SerTrp: 0.722 ± 0.039	2.601SerTyr: 2.601 ± 0.068	0.0SerXaa: 0.0 ± 0.0
Thr	2.304ThrAla: 2.304 ± 0.058	0.299ThrCys: 0.299 ± 0.021	1.753ThrAsp: 1.753 ± 0.057	2.549ThrGlu: 2.549 ± 0.069	2.37ThrPhe: 2.37 ± 0.069	3.212ThrGly: 3.212 ± 0.082	0.775ThrHis: 0.775 ± 0.04	3.668ThrIle: 3.668 ± 0.085	2.939ThrLys: 2.939 ± 0.081	5.038ThrLeu: 5.038 ± 0.102	0.715ThrMet: 0.715 ± 0.036	1.784ThrAsn: 1.784 ± 0.052	2.326ThrPro: 2.326 ± 0.057	1.109ThrGln: 1.109 ± 0.045	1.504ThrArg: 1.504 ± 0.056	2.501ThrSer: 2.501 ± 0.064	2.143ThrThr: 2.143 ± 0.07	2.69ThrVal: 2.69 ± 0.089	0.443ThrTrp: 0.443 ± 0.026	2.019ThrTyr: 2.019 ± 0.073	0.0ThrXaa: 0.0 ± 0.0
Val	3.609ValAla: 3.609 ± 0.087	0.455ValCys: 0.455 ± 0.033	3.472ValAsp: 3.472 ± 0.086	5.106ValGlu: 5.106 ± 0.097	3.404ValPhe: 3.404 ± 0.082	4.448ValGly: 4.448 ± 0.108	0.81ValHis: 0.81 ± 0.039	6.523ValIle: 6.523 ± 0.124	5.379ValLys: 5.379 ± 0.103	6.775ValLeu: 6.775 ± 0.124	1.328ValMet: 1.328 ± 0.046	2.834ValAsn: 2.834 ± 0.075	2.648ValPro: 2.648 ± 0.074	1.291ValGln: 1.291 ± 0.053	2.928ValArg: 2.928 ± 0.075	3.768ValSer: 3.768 ± 0.095	2.335ValThr: 2.335 ± 0.073	4.606ValVal: 4.606 ± 0.099	0.682ValTrp: 0.682 ± 0.042	2.87ValTyr: 2.87 ± 0.075	0.0ValXaa: 0.0 ± 0.0
Trp	0.623TrpAla: 0.623 ± 0.035	0.082TrpCys: 0.082 ± 0.012	0.663TrpAsp: 0.663 ± 0.037	1.13TrpGlu: 1.13 ± 0.046	0.455TrpPhe: 0.455 ± 0.032	0.978TrpGly: 0.978 ± 0.051	0.205TrpHis: 0.205 ± 0.02	0.852TrpIle: 0.852 ± 0.039	0.999TrpLys: 0.999 ± 0.047	0.826TrpLeu: 0.826 ± 0.039	0.243TrpMet: 0.243 ± 0.022	0.638TrpAsn: 0.638 ± 0.033	0.259TrpPro: 0.259 ± 0.026	0.343TrpGln: 0.343 ± 0.023	0.568TrpArg: 0.568 ± 0.032	0.574TrpSer: 0.574 ± 0.031	0.465TrpThr: 0.465 ± 0.034	0.614TrpVal: 0.614 ± 0.036	0.205TrpTrp: 0.205 ± 0.022	0.446TrpTyr: 0.446 ± 0.031	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.208TyrAla: 2.208 ± 0.069	0.31TyrCys: 0.31 ± 0.025	2.057TyrAsp: 2.057 ± 0.065	2.942TyrGlu: 2.942 ± 0.077	2.605TyrPhe: 2.605 ± 0.073	2.835TyrGly: 2.835 ± 0.075	0.672TyrHis: 0.672 ± 0.035	3.803TyrIle: 3.803 ± 0.099	3.418TyrLys: 3.418 ± 0.081	4.831TyrLeu: 4.831 ± 0.103	0.831TyrMet: 0.831 ± 0.039	2.045TyrAsn: 2.045 ± 0.064	2.022TyrPro: 2.022 ± 0.054	1.067TyrGln: 1.067 ± 0.041	1.854TyrArg: 1.854 ± 0.059	2.662TyrSer: 2.662 ± 0.077	1.868TyrThr: 1.868 ± 0.063	2.703TyrVal: 2.703 ± 0.07	0.493TyrTrp: 0.493 ± 0.031	2.125TyrTyr: 2.125 ± 0.073	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 1743 proteins (571687 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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