Amino acid dipepetide frequency for Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.204AlaAla: 8.204 ± 0.067
1.123AlaCys: 1.123 ± 0.016
4.095AlaAsp: 4.095 ± 0.029
4.876AlaGlu: 4.876 ± 0.042
3.047AlaPhe: 3.047 ± 0.025
5.41AlaGly: 5.41 ± 0.042
1.653AlaHis: 1.653 ± 0.018
4.414AlaIle: 4.414 ± 0.031
4.159AlaLys: 4.159 ± 0.032
7.261AlaLeu: 7.261 ± 0.041
2.023AlaMet: 2.023 ± 0.02
2.928AlaAsn: 2.928 ± 0.024
4.619AlaPro: 4.619 ± 0.047
3.307AlaGln: 3.307 ± 0.025
4.423AlaArg: 4.423 ± 0.029
6.999AlaSer: 6.999 ± 0.041
5.164AlaThr: 5.164 ± 0.034
5.14AlaVal: 5.14 ± 0.03
1.159AlaTrp: 1.159 ± 0.016
2.09AlaTyr: 2.09 ± 0.02
0.0AlaXaa: 0.0 ± 0.0
Cys
0.946CysAla: 0.946 ± 0.013
0.282CysCys: 0.282 ± 0.009
0.731CysAsp: 0.731 ± 0.011
0.642CysGlu: 0.642 ± 0.012
0.596CysPhe: 0.596 ± 0.009
0.968CysGly: 0.968 ± 0.017
0.361CysHis: 0.361 ± 0.008
0.779CysIle: 0.779 ± 0.011
0.604CysLys: 0.604 ± 0.01
1.313CysLeu: 1.313 ± 0.016
0.304CysMet: 0.304 ± 0.007
0.502CysAsn: 0.502 ± 0.009
0.699CysPro: 0.699 ± 0.014
0.515CysGln: 0.515 ± 0.01
0.795CysArg: 0.795 ± 0.013
0.977CysSer: 0.977 ± 0.014
0.765CysThr: 0.765 ± 0.013
0.845CysVal: 0.845 ± 0.015
0.225CysTrp: 0.225 ± 0.007
0.401CysTyr: 0.401 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
4.641AspAla: 4.641 ± 0.031
0.692AspCys: 0.692 ± 0.012
4.625AspAsp: 4.625 ± 0.038
4.641AspGlu: 4.641 ± 0.038
2.268AspPhe: 2.268 ± 0.023
4.073AspGly: 4.073 ± 0.029
1.274AspHis: 1.274 ± 0.015
3.274AspIle: 3.274 ± 0.023
2.826AspLys: 2.826 ± 0.021
5.06AspLeu: 5.06 ± 0.035
1.424AspMet: 1.424 ± 0.016
2.189AspAsn: 2.189 ± 0.021
3.264AspPro: 3.264 ± 0.024
2.0AspGln: 2.0 ± 0.019
3.015AspArg: 3.015 ± 0.029
4.281AspSer: 4.281 ± 0.028
3.183AspThr: 3.183 ± 0.023
3.726AspVal: 3.726 ± 0.024
0.941AspTrp: 0.941 ± 0.012
1.655AspTyr: 1.655 ± 0.017
0.0AspXaa: 0.0 ± 0.0
Glu
5.335GluAla: 5.335 ± 0.045
0.687GluCys: 0.687 ± 0.012
4.228GluAsp: 4.228 ± 0.03
5.239GluGlu: 5.239 ± 0.06
1.99GluPhe: 1.99 ± 0.016
3.579GluGly: 3.579 ± 0.028
1.414GluHis: 1.414 ± 0.016
3.115GluIle: 3.115 ± 0.023
3.767GluLys: 3.767 ± 0.031
5.083GluLeu: 5.083 ± 0.035
1.494GluMet: 1.494 ± 0.016
2.375GluAsn: 2.375 ± 0.021
2.958GluPro: 2.958 ± 0.037
2.454GluGln: 2.454 ± 0.023
3.693GluArg: 3.693 ± 0.034
4.389GluSer: 4.389 ± 0.034
3.852GluThr: 3.852 ± 0.033
3.506GluVal: 3.506 ± 0.025
0.912GluTrp: 0.912 ± 0.012
1.67GluTyr: 1.67 ± 0.017
0.0GluXaa: 0.0 ± 0.0
Phe
2.953PheAla: 2.953 ± 0.021
0.595PheCys: 0.595 ± 0.011
2.346PheAsp: 2.346 ± 0.019
2.184PheGlu: 2.184 ± 0.02
1.655PhePhe: 1.655 ± 0.02
2.843PheGly: 2.843 ± 0.026
0.918PheHis: 0.918 ± 0.014
1.941PheIle: 1.941 ± 0.019
1.669PheLys: 1.669 ± 0.018
3.377PheLeu: 3.377 ± 0.027
0.85PheMet: 0.85 ± 0.01
1.55PheAsn: 1.55 ± 0.015
1.883PhePro: 1.883 ± 0.017
1.43PheGln: 1.43 ± 0.016
1.869PheArg: 1.869 ± 0.017
2.99PheSer: 2.99 ± 0.022
2.223PheThr: 2.223 ± 0.022
2.42PheVal: 2.42 ± 0.02
0.669PheTrp: 0.669 ± 0.01
1.124PheTyr: 1.124 ± 0.014
0.0PheXaa: 0.0 ± 0.0
Gly
4.951GlyAla: 4.951 ± 0.037
0.935GlyCys: 0.935 ± 0.012
3.701GlyAsp: 3.701 ± 0.032
3.481GlyGlu: 3.481 ± 0.03
2.797GlyPhe: 2.797 ± 0.024
5.353GlyGly: 5.353 ± 0.054
1.685GlyHis: 1.685 ± 0.017
3.599GlyIle: 3.599 ± 0.028
3.443GlyLys: 3.443 ± 0.032
5.923GlyLeu: 5.923 ± 0.04
1.598GlyMet: 1.598 ± 0.018
2.699GlyAsn: 2.699 ± 0.024
3.252GlyPro: 3.252 ± 0.032
2.608GlyGln: 2.608 ± 0.023
3.898GlyArg: 3.898 ± 0.026
5.645GlySer: 5.645 ± 0.036
3.992GlyThr: 3.992 ± 0.04
4.174GlyVal: 4.174 ± 0.033
1.169GlyTrp: 1.169 ± 0.015
2.144GlyTyr: 2.144 ± 0.021
0.0GlyXaa: 0.0 ± 0.0
His
1.731HisAla: 1.731 ± 0.02
0.351HisCys: 0.351 ± 0.007
1.447HisAsp: 1.447 ± 0.016
1.36HisGlu: 1.36 ± 0.016
0.906HisPhe: 0.906 ± 0.012
1.719HisGly: 1.719 ± 0.019
0.851HisHis: 0.851 ± 0.019
1.251HisIle: 1.251 ± 0.015
1.007HisLys: 1.007 ± 0.013
2.179HisLeu: 2.179 ± 0.022
0.534HisMet: 0.534 ± 0.01
0.913HisAsn: 0.913 ± 0.014
1.524HisPro: 1.524 ± 0.018
1.058HisGln: 1.058 ± 0.017
1.463HisArg: 1.463 ± 0.016
1.794HisSer: 1.794 ± 0.016
1.214HisThr: 1.214 ± 0.014
1.455HisVal: 1.455 ± 0.013
0.356HisTrp: 0.356 ± 0.008
0.722HisTyr: 0.722 ± 0.013
0.0HisXaa: 0.0 ± 0.0
Ile
4.256IleAla: 4.256 ± 0.028
0.803IleCys: 0.803 ± 0.013
3.047IleAsp: 3.047 ± 0.023
3.052IleGlu: 3.052 ± 0.025
2.044IlePhe: 2.044 ± 0.02
3.277IleGly: 3.277 ± 0.026
1.227IleHis: 1.227 ± 0.013
2.711IleIle: 2.711 ± 0.025
2.448IleLys: 2.448 ± 0.022
4.594IleLeu: 4.594 ± 0.032
1.133IleMet: 1.133 ± 0.012
1.995IleAsn: 1.995 ± 0.02
3.082IlePro: 3.082 ± 0.019
1.978IleGln: 1.978 ± 0.017
2.784IleArg: 2.784 ± 0.021
3.965IleSer: 3.965 ± 0.025
3.035IleThr: 3.035 ± 0.033
3.335IleVal: 3.335 ± 0.027
0.802IleTrp: 0.802 ± 0.014
1.451IleTyr: 1.451 ± 0.017
0.0IleXaa: 0.0 ± 0.0
Lys
4.327LysAla: 4.327 ± 0.033
0.575LysCys: 0.575 ± 0.013
3.176LysAsp: 3.176 ± 0.023
3.463LysGlu: 3.463 ± 0.028
1.545LysPhe: 1.545 ± 0.018
3.101LysGly: 3.101 ± 0.027
1.214LysHis: 1.214 ± 0.018
2.392LysIle: 2.392 ± 0.023
3.587LysLys: 3.587 ± 0.041
4.185LysLeu: 4.185 ± 0.029
1.117LysMet: 1.117 ± 0.014
1.973LysAsn: 1.973 ± 0.019
2.97LysPro: 2.97 ± 0.032
1.978LysGln: 1.978 ± 0.02
3.367LysArg: 3.367 ± 0.031
3.73LysSer: 3.73 ± 0.028
3.223LysThr: 3.223 ± 0.022
2.981LysVal: 2.981 ± 0.026
0.732LysTrp: 0.732 ± 0.011
1.439LysTyr: 1.439 ± 0.018
0.0LysXaa: 0.0 ± 0.0
Leu
7.387LeuAla: 7.387 ± 0.042
1.265LeuCys: 1.265 ± 0.017
5.144LeuAsp: 5.144 ± 0.034
5.372LeuGlu: 5.372 ± 0.035
3.316LeuPhe: 3.316 ± 0.026
5.734LeuGly: 5.734 ± 0.038
2.114LeuHis: 2.114 ± 0.021
4.072LeuIle: 4.072 ± 0.035
4.283LeuLys: 4.283 ± 0.031
7.849LeuLeu: 7.849 ± 0.056
1.863LeuMet: 1.863 ± 0.018
3.217LeuAsn: 3.217 ± 0.022
5.196LeuPro: 5.196 ± 0.031
3.666LeuGln: 3.666 ± 0.031
5.304LeuArg: 5.304 ± 0.038
7.179LeuSer: 7.179 ± 0.04
4.746LeuThr: 4.746 ± 0.03
5.42LeuVal: 5.42 ± 0.038
1.232LeuTrp: 1.232 ± 0.016
2.322LeuTyr: 2.322 ± 0.023
0.0LeuXaa: 0.0 ± 0.0
Met
2.313MetAla: 2.313 ± 0.019
0.281MetCys: 0.281 ± 0.006
1.338MetAsp: 1.338 ± 0.014
1.322MetGlu: 1.322 ± 0.016
0.801MetPhe: 0.801 ± 0.012
1.53MetGly: 1.53 ± 0.017
0.505MetHis: 0.505 ± 0.009
1.094MetIle: 1.094 ± 0.014
1.094MetLys: 1.094 ± 0.014
1.851MetLeu: 1.851 ± 0.018
0.649MetMet: 0.649 ± 0.011
0.87MetAsn: 0.87 ± 0.012
1.366MetPro: 1.366 ± 0.016
0.857MetGln: 0.857 ± 0.014
1.279MetArg: 1.279 ± 0.014
2.12MetSer: 2.12 ± 0.02
1.455MetThr: 1.455 ± 0.016
1.368MetVal: 1.368 ± 0.015
0.282MetTrp: 0.282 ± 0.006
0.554MetTyr: 0.554 ± 0.01
0.0MetXaa: 0.0 ± 0.0
Asn
3.097AsnAla: 3.097 ± 0.023
0.503AsnCys: 0.503 ± 0.01
2.248AsnAsp: 2.248 ± 0.02
2.159AsnGlu: 2.159 ± 0.018
1.411AsnPhe: 1.411 ± 0.015
3.045AsnGly: 3.045 ± 0.028
0.913AsnHis: 0.913 ± 0.011
2.18AsnIle: 2.18 ± 0.02
1.886AsnLys: 1.886 ± 0.019
3.329AsnLeu: 3.329 ± 0.024
0.977AsnMet: 0.977 ± 0.013
1.735AsnAsn: 1.735 ± 0.021
2.426AsnPro: 2.426 ± 0.019
1.428AsnGln: 1.428 ± 0.019
1.984AsnArg: 1.984 ± 0.02
2.921AsnSer: 2.921 ± 0.025
2.341AsnThr: 2.341 ± 0.02
2.373AsnVal: 2.373 ± 0.021
0.595AsnTrp: 0.595 ± 0.011
1.12AsnTyr: 1.12 ± 0.013
0.0AsnXaa: 0.0 ± 0.0
Pro
4.808ProAla: 4.808 ± 0.044
0.584ProCys: 0.584 ± 0.011
3.256ProAsp: 3.256 ± 0.022
3.935ProGlu: 3.935 ± 0.028
2.041ProPhe: 2.041 ± 0.016
3.839ProGly: 3.839 ± 0.048
1.274ProHis: 1.274 ± 0.016
2.571ProIle: 2.571 ± 0.021
2.865ProLys: 2.865 ± 0.027
4.475ProLeu: 4.475 ± 0.029
1.162ProMet: 1.162 ± 0.015
2.207ProAsn: 2.207 ± 0.017
4.616ProPro: 4.616 ± 0.065
2.508ProGln: 2.508 ± 0.029
3.222ProArg: 3.222 ± 0.031
5.677ProSer: 5.677 ± 0.048
3.984ProThr: 3.984 ± 0.041
3.625ProVal: 3.625 ± 0.032
0.774ProTrp: 0.774 ± 0.014
1.499ProTyr: 1.499 ± 0.018
0.0ProXaa: 0.0 ± 0.0
Gln
3.395GlnAla: 3.395 ± 0.027
0.474GlnCys: 0.474 ± 0.009
2.32GlnAsp: 2.32 ± 0.021
2.449GlnGlu: 2.449 ± 0.024
1.303GlnPhe: 1.303 ± 0.014
2.54GlnGly: 2.54 ± 0.021
1.08GlnHis: 1.08 ± 0.015
1.89GlnIle: 1.89 ± 0.018
2.006GlnLys: 2.006 ± 0.019
3.352GlnLeu: 3.352 ± 0.025
0.918GlnMet: 0.918 ± 0.015
1.633GlnAsn: 1.633 ± 0.019
2.573GlnPro: 2.573 ± 0.033
2.467GlnGln: 2.467 ± 0.05
2.52GlnArg: 2.52 ± 0.023
3.129GlnSer: 3.129 ± 0.026
2.36GlnThr: 2.36 ± 0.021
2.284GlnVal: 2.284 ± 0.018
0.603GlnTrp: 0.603 ± 0.01
1.17GlnTyr: 1.17 ± 0.015
0.0GlnXaa: 0.0 ± 0.0
Arg
4.192ArgAla: 4.192 ± 0.027
0.742ArgCys: 0.742 ± 0.012
3.416ArgAsp: 3.416 ± 0.031
3.526ArgGlu: 3.526 ± 0.033
2.077ArgPhe: 2.077 ± 0.019
3.503ArgGly: 3.503 ± 0.028
1.54ArgHis: 1.54 ± 0.016
2.835ArgIle: 2.835 ± 0.02
3.288ArgLys: 3.288 ± 0.027
5.202ArgLeu: 5.202 ± 0.036
1.319ArgMet: 1.319 ± 0.015
2.273ArgAsn: 2.273 ± 0.018
3.382ArgPro: 3.382 ± 0.033
2.552ArgGln: 2.552 ± 0.026
4.706ArgArg: 4.706 ± 0.041
4.572ArgSer: 4.572 ± 0.038
3.117ArgThr: 3.117 ± 0.025
3.254ArgVal: 3.254 ± 0.023
0.918ArgTrp: 0.918 ± 0.011
1.656ArgTyr: 1.656 ± 0.018
0.0ArgXaa: 0.0 ± 0.0
Ser
6.174SerAla: 6.174 ± 0.035
0.976SerCys: 0.976 ± 0.015
4.473SerAsp: 4.473 ± 0.03
4.253SerGlu: 4.253 ± 0.032
3.124SerPhe: 3.124 ± 0.024
5.436SerGly: 5.436 ± 0.041
1.993SerHis: 1.993 ± 0.021
4.223SerIle: 4.223 ± 0.031
3.988SerLys: 3.988 ± 0.028
7.052SerLeu: 7.052 ± 0.04
1.829SerMet: 1.829 ± 0.019
3.179SerAsn: 3.179 ± 0.024
5.221SerPro: 5.221 ± 0.041
3.371SerGln: 3.371 ± 0.027
4.858SerArg: 4.858 ± 0.036
8.323SerSer: 8.323 ± 0.061
5.575SerThr: 5.575 ± 0.045
4.631SerVal: 4.631 ± 0.03
1.2SerTrp: 1.2 ± 0.013
2.157SerTyr: 2.157 ± 0.018
0.0SerXaa: 0.0 ± 0.0
Thr
5.046ThrAla: 5.046 ± 0.03
0.828ThrCys: 0.828 ± 0.012
3.04ThrAsp: 3.04 ± 0.021
3.42ThrGlu: 3.42 ± 0.032
2.292ThrPhe: 2.292 ± 0.02
4.133ThrGly: 4.133 ± 0.037
1.271ThrHis: 1.271 ± 0.015
3.348ThrIle: 3.348 ± 0.037
2.982ThrLys: 2.982 ± 0.024
5.169ThrLeu: 5.169 ± 0.029
1.289ThrMet: 1.289 ± 0.015
2.265ThrAsn: 2.265 ± 0.02
4.222ThrPro: 4.222 ± 0.037
2.203ThrGln: 2.203 ± 0.022
3.131ThrArg: 3.131 ± 0.027
5.418ThrSer: 5.418 ± 0.043
4.675ThrThr: 4.675 ± 0.076
3.917ThrVal: 3.917 ± 0.051
0.929ThrTrp: 0.929 ± 0.013
1.65ThrTyr: 1.65 ± 0.021
0.0ThrXaa: 0.0 ± 0.0
Val
5.127ValAla: 5.127 ± 0.033
0.879ValCys: 0.879 ± 0.013
3.785ValAsp: 3.785 ± 0.028
3.896ValGlu: 3.896 ± 0.033
2.5ValPhe: 2.5 ± 0.019
3.907ValGly: 3.907 ± 0.032
1.384ValHis: 1.384 ± 0.016
3.091ValIle: 3.091 ± 0.028
3.076ValLys: 3.076 ± 0.024
5.426ValLeu: 5.426 ± 0.033
1.392ValMet: 1.392 ± 0.015
2.292ValAsn: 2.292 ± 0.018
3.559ValPro: 3.559 ± 0.027
2.35ValGln: 2.35 ± 0.019
3.24ValArg: 3.24 ± 0.025
4.753ValSer: 4.753 ± 0.029
3.717ValThr: 3.717 ± 0.046
4.311ValVal: 4.311 ± 0.033
0.873ValTrp: 0.873 ± 0.012
1.742ValTyr: 1.742 ± 0.017
0.0ValXaa: 0.0 ± 0.0
Trp
1.141TrpAla: 1.141 ± 0.015
0.219TrpCys: 0.219 ± 0.005
0.946TrpAsp: 0.946 ± 0.015
0.876TrpGlu: 0.876 ± 0.012
0.584TrpPhe: 0.584 ± 0.01
0.976TrpGly: 0.976 ± 0.014
0.374TrpHis: 0.374 ± 0.008
0.826TrpIle: 0.826 ± 0.012
0.858TrpLys: 0.858 ± 0.014
1.399TrpLeu: 1.399 ± 0.017
0.392TrpMet: 0.392 ± 0.008
0.679TrpAsn: 0.679 ± 0.011
0.633TrpPro: 0.633 ± 0.01
0.592TrpGln: 0.592 ± 0.01
0.916TrpArg: 0.916 ± 0.013
1.111TrpSer: 1.111 ± 0.013
0.962TrpThr: 0.962 ± 0.012
0.91TrpVal: 0.91 ± 0.013
0.292TrpTrp: 0.292 ± 0.007
0.457TrpTyr: 0.457 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.071TyrAla: 2.071 ± 0.019
0.458TyrCys: 0.458 ± 0.009
1.689TyrAsp: 1.689 ± 0.02
1.592TyrGlu: 1.592 ± 0.019
1.192TyrPhe: 1.192 ± 0.015
2.084TyrGly: 2.084 ± 0.02
0.79TyrHis: 0.79 ± 0.013
1.413TyrIle: 1.413 ± 0.016
1.239TyrLys: 1.239 ± 0.016
2.601TyrLeu: 2.601 ± 0.026
0.662TyrMet: 0.662 ± 0.01
1.194TyrAsn: 1.194 ± 0.015
1.475TyrPro: 1.475 ± 0.018
1.146TyrGln: 1.146 ± 0.014
1.604TyrArg: 1.604 ± 0.016
2.061TyrSer: 2.061 ± 0.018
1.649TyrThr: 1.649 ± 0.02
1.622TyrVal: 1.622 ± 0.018
0.478TyrTrp: 0.478 ± 0.009
0.932TyrTyr: 0.932 ± 0.013
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 14163 proteins (6396450 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski