Amino acid dipepetide frequency for Blyttiomyces helicus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.692AlaAla: 12.692 ± 0.1	1.377AlaCys: 1.377 ± 0.02	4.975AlaAsp: 4.975 ± 0.045	5.555AlaGlu: 5.555 ± 0.059	3.241AlaPhe: 3.241 ± 0.029	6.995AlaGly: 6.995 ± 0.047	2.113AlaHis: 2.113 ± 0.022	4.198AlaIle: 4.198 ± 0.034	4.005AlaLys: 4.005 ± 0.034	8.664AlaLeu: 8.664 ± 0.053	1.861AlaMet: 1.861 ± 0.025	2.815AlaAsn: 2.815 ± 0.031	7.2AlaPro: 7.2 ± 0.065	3.021AlaGln: 3.021 ± 0.037	6.419AlaArg: 6.419 ± 0.049	8.488AlaSer: 8.488 ± 0.058	6.093AlaThr: 6.093 ± 0.05	6.54AlaVal: 6.54 ± 0.047	1.115AlaTrp: 1.115 ± 0.019	1.841AlaTyr: 1.841 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	1.25CysAla: 1.25 ± 0.017	0.333CysCys: 0.333 ± 0.009	0.686CysAsp: 0.686 ± 0.013	0.737CysGlu: 0.737 ± 0.013	0.579CysPhe: 0.579 ± 0.012	1.203CysGly: 1.203 ± 0.019	0.363CysHis: 0.363 ± 0.009	0.688CysIle: 0.688 ± 0.013	0.576CysLys: 0.576 ± 0.011	1.394CysLeu: 1.394 ± 0.016	0.289CysMet: 0.289 ± 0.008	0.451CysAsn: 0.451 ± 0.011	1.027CysPro: 1.027 ± 0.019	0.447CysGln: 0.447 ± 0.009	1.017CysArg: 1.017 ± 0.016	1.209CysSer: 1.209 ± 0.014	0.845CysThr: 0.845 ± 0.015	0.932CysVal: 0.932 ± 0.017	0.244CysTrp: 0.244 ± 0.007	0.318CysTyr: 0.318 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.481AspAla: 5.481 ± 0.043	0.691AspCys: 0.691 ± 0.014	3.927AspAsp: 3.927 ± 0.049	3.897AspGlu: 3.897 ± 0.04	1.955AspPhe: 1.955 ± 0.024	4.222AspGly: 4.222 ± 0.038	1.196AspHis: 1.196 ± 0.02	2.507AspIle: 2.507 ± 0.028	1.774AspLys: 1.774 ± 0.026	4.989AspLeu: 4.989 ± 0.041	1.023AspMet: 1.023 ± 0.015	1.456AspAsn: 1.456 ± 0.023	3.805AspPro: 3.805 ± 0.037	1.471AspGln: 1.471 ± 0.019	3.434AspArg: 3.434 ± 0.042	3.89AspSer: 3.89 ± 0.038	2.508AspThr: 2.508 ± 0.024	3.86AspVal: 3.86 ± 0.038	0.74AspTrp: 0.74 ± 0.013	1.213AspTyr: 1.213 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.52GluAla: 5.52 ± 0.059	0.682GluCys: 0.682 ± 0.011	3.701GluAsp: 3.701 ± 0.036	5.14GluGlu: 5.14 ± 0.063	1.776GluPhe: 1.776 ± 0.023	4.209GluGly: 4.209 ± 0.036	1.184GluHis: 1.184 ± 0.017	2.752GluIle: 2.752 ± 0.031	3.147GluLys: 3.147 ± 0.038	4.976GluLeu: 4.976 ± 0.05	1.373GluMet: 1.373 ± 0.017	1.914GluAsn: 1.914 ± 0.024	2.821GluPro: 2.821 ± 0.037	1.835GluGln: 1.835 ± 0.027	4.395GluArg: 4.395 ± 0.053	3.981GluSer: 3.981 ± 0.036	3.145GluThr: 3.145 ± 0.03	3.817GluVal: 3.817 ± 0.042	0.805GluTrp: 0.805 ± 0.016	1.225GluTyr: 1.225 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.342PheAla: 3.342 ± 0.036	0.615PheCys: 0.615 ± 0.012	2.129PheAsp: 2.129 ± 0.023	2.041PheGlu: 2.041 ± 0.024	1.521PhePhe: 1.521 ± 0.023	2.626PheGly: 2.626 ± 0.031	0.876PheHis: 0.876 ± 0.017	1.548PheIle: 1.548 ± 0.022	1.35PheLys: 1.35 ± 0.019	3.415PheLeu: 3.415 ± 0.031	0.683PheMet: 0.683 ± 0.014	1.237PheAsn: 1.237 ± 0.019	2.12PhePro: 2.12 ± 0.023	1.097PheGln: 1.097 ± 0.016	2.059PheArg: 2.059 ± 0.023	2.843PheSer: 2.843 ± 0.026	1.931PheThr: 1.931 ± 0.024	2.388PheVal: 2.388 ± 0.025	0.529PheTrp: 0.529 ± 0.012	0.92PheTyr: 0.92 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	6.565GlyAla: 6.565 ± 0.044	1.12GlyCys: 1.12 ± 0.019	3.794GlyAsp: 3.794 ± 0.038	4.092GlyGlu: 4.092 ± 0.035	2.499GlyPhe: 2.499 ± 0.03	7.724GlyGly: 7.724 ± 0.08	1.531GlyHis: 1.531 ± 0.022	3.089GlyIle: 3.089 ± 0.032	3.281GlyLys: 3.281 ± 0.032	5.436GlyLeu: 5.436 ± 0.036	1.465GlyMet: 1.465 ± 0.02	2.248GlyAsn: 2.248 ± 0.033	3.871GlyPro: 3.871 ± 0.036	2.03GlyGln: 2.03 ± 0.024	5.123GlyArg: 5.123 ± 0.042	6.008GlySer: 6.008 ± 0.043	4.002GlyThr: 4.002 ± 0.043	4.89GlyVal: 4.89 ± 0.043	1.156GlyTrp: 1.156 ± 0.018	1.593GlyTyr: 1.593 ± 0.029	0.0GlyXaa: 0.0 ± 0.0
His	2.13HisAla: 2.13 ± 0.027	0.387HisCys: 0.387 ± 0.01	1.159HisAsp: 1.159 ± 0.015	1.164HisGlu: 1.164 ± 0.019	0.91HisPhe: 0.91 ± 0.015	1.569HisGly: 1.569 ± 0.021	0.929HisHis: 0.929 ± 0.021	1.111HisIle: 1.111 ± 0.017	0.805HisLys: 0.805 ± 0.015	2.455HisLeu: 2.455 ± 0.026	0.4HisMet: 0.4 ± 0.009	0.693HisAsn: 0.693 ± 0.013	2.137HisPro: 2.137 ± 0.029	0.899HisGln: 0.899 ± 0.017	1.793HisArg: 1.793 ± 0.022	1.8HisSer: 1.8 ± 0.024	1.194HisThr: 1.194 ± 0.017	1.537HisVal: 1.537 ± 0.02	0.29HisTrp: 0.29 ± 0.008	0.55HisTyr: 0.55 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.391IleAla: 4.391 ± 0.035	0.754IleCys: 0.754 ± 0.013	2.652IleAsp: 2.652 ± 0.027	2.608IleGlu: 2.608 ± 0.028	1.764IlePhe: 1.764 ± 0.025	2.958IleGly: 2.958 ± 0.031	1.051IleHis: 1.051 ± 0.017	2.028IleIle: 2.028 ± 0.025	1.897IleLys: 1.897 ± 0.025	4.222IleLeu: 4.222 ± 0.031	0.842IleMet: 0.842 ± 0.015	1.526IleAsn: 1.526 ± 0.018	3.022IlePro: 3.022 ± 0.031	1.421IleGln: 1.421 ± 0.018	2.619IleArg: 2.619 ± 0.022	3.521IleSer: 3.521 ± 0.031	2.506IleThr: 2.506 ± 0.03	3.229IleVal: 3.229 ± 0.029	0.587IleTrp: 0.587 ± 0.013	1.046IleTyr: 1.046 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	3.722LysAla: 3.722 ± 0.045	0.547LysCys: 0.547 ± 0.011	2.201LysAsp: 2.201 ± 0.027	2.921LysGlu: 2.921 ± 0.036	1.325LysPhe: 1.325 ± 0.018	2.824LysGly: 2.824 ± 0.029	0.944LysHis: 0.944 ± 0.016	2.147LysIle: 2.147 ± 0.024	2.989LysLys: 2.989 ± 0.04	3.709LysLeu: 3.709 ± 0.034	0.984LysMet: 0.984 ± 0.017	1.506LysAsn: 1.506 ± 0.018	2.319LysPro: 2.319 ± 0.034	1.432LysGln: 1.432 ± 0.022	3.193LysArg: 3.193 ± 0.035	2.972LysSer: 2.972 ± 0.03	2.522LysThr: 2.522 ± 0.028	2.635LysVal: 2.635 ± 0.026	0.572LysTrp: 0.572 ± 0.012	1.052LysTyr: 1.052 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	9.058LeuAla: 9.058 ± 0.055	1.377LeuCys: 1.377 ± 0.018	4.905LeuAsp: 4.905 ± 0.034	5.27LeuGlu: 5.27 ± 0.054	3.258LeuPhe: 3.258 ± 0.035	5.571LeuGly: 5.571 ± 0.038	2.42LeuHis: 2.42 ± 0.025	3.641LeuIle: 3.641 ± 0.029	3.848LeuLys: 3.848 ± 0.037	8.853LeuLeu: 8.853 ± 0.057	1.678LeuMet: 1.678 ± 0.021	2.862LeuAsn: 2.862 ± 0.03	6.648LeuPro: 6.648 ± 0.05	3.328LeuGln: 3.328 ± 0.034	6.381LeuArg: 6.381 ± 0.049	7.163LeuSer: 7.163 ± 0.042	5.07LeuThr: 5.07 ± 0.038	5.956LeuVal: 5.956 ± 0.05	1.078LeuTrp: 1.078 ± 0.017	1.863LeuTyr: 1.863 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.744MetAla: 1.744 ± 0.02	0.276MetCys: 0.276 ± 0.009	1.11MetAsp: 1.11 ± 0.016	1.238MetGlu: 1.238 ± 0.016	0.689MetPhe: 0.689 ± 0.014	1.318MetGly: 1.318 ± 0.019	0.474MetHis: 0.474 ± 0.01	0.84MetIle: 0.84 ± 0.014	0.918MetLys: 0.918 ± 0.016	1.718MetLeu: 1.718 ± 0.02	0.468MetMet: 0.468 ± 0.011	0.684MetAsn: 0.684 ± 0.014	1.132MetPro: 1.132 ± 0.016	0.776MetGln: 0.776 ± 0.013	1.354MetArg: 1.354 ± 0.019	1.616MetSer: 1.616 ± 0.018	1.159MetThr: 1.159 ± 0.016	1.207MetVal: 1.207 ± 0.018	0.255MetTrp: 0.255 ± 0.008	0.452MetTyr: 0.452 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.935AsnAla: 2.935 ± 0.033	0.47AsnCys: 0.47 ± 0.01	1.574AsnAsp: 1.574 ± 0.02	1.593AsnGlu: 1.593 ± 0.021	1.213AsnPhe: 1.213 ± 0.017	2.331AsnGly: 2.331 ± 0.033	0.719AsnHis: 0.719 ± 0.012	1.738AsnIle: 1.738 ± 0.026	1.204AsnLys: 1.204 ± 0.016	3.112AsnLeu: 3.112 ± 0.03	0.693AsnMet: 0.693 ± 0.012	1.118AsnAsn: 1.118 ± 0.028	2.372AsnPro: 2.372 ± 0.029	1.015AsnGln: 1.015 ± 0.018	1.839AsnArg: 1.839 ± 0.022	2.38AsnSer: 2.38 ± 0.032	1.776AsnThr: 1.776 ± 0.023	2.247AsnVal: 2.247 ± 0.025	0.386AsnTrp: 0.386 ± 0.009	0.8AsnTyr: 0.8 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	7.75ProAla: 7.75 ± 0.07	0.797ProCys: 0.797 ± 0.014	3.344ProAsp: 3.344 ± 0.031	3.372ProGlu: 3.372 ± 0.037	2.194ProPhe: 2.194 ± 0.026	3.947ProGly: 3.947 ± 0.034	1.852ProHis: 1.852 ± 0.023	2.81ProIle: 2.81 ± 0.029	2.37ProLys: 2.37 ± 0.029	6.112ProLeu: 6.112 ± 0.044	1.048ProMet: 1.048 ± 0.018	2.094ProAsn: 2.094 ± 0.024	8.136ProPro: 8.136 ± 0.1	2.315ProGln: 2.315 ± 0.027	4.444ProArg: 4.444 ± 0.047	7.235ProSer: 7.235 ± 0.058	5.087ProThr: 5.087 ± 0.048	4.261ProVal: 4.261 ± 0.039	0.686ProTrp: 0.686 ± 0.017	1.258ProTyr: 1.258 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	2.837GlnAla: 2.837 ± 0.035	0.452GlnCys: 0.452 ± 0.009	1.462GlnAsp: 1.462 ± 0.019	1.779GlnGlu: 1.779 ± 0.027	1.077GlnPhe: 1.077 ± 0.013	1.959GlnGly: 1.959 ± 0.026	0.871GlnHis: 0.871 ± 0.016	1.634GlnIle: 1.634 ± 0.022	1.551GlnLys: 1.551 ± 0.021	3.072GlnLeu: 3.072 ± 0.029	0.761GlnMet: 0.761 ± 0.013	1.187GlnAsn: 1.187 ± 0.018	2.293GlnPro: 2.293 ± 0.03	1.876GlnGln: 1.876 ± 0.062	2.353GlnArg: 2.353 ± 0.028	2.445GlnSer: 2.445 ± 0.023	2.026GlnThr: 2.026 ± 0.022	1.884GlnVal: 1.884 ± 0.023	0.428GlnTrp: 0.428 ± 0.01	0.771GlnTyr: 0.771 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	6.252ArgAla: 6.252 ± 0.053	1.012ArgCys: 1.012 ± 0.015	3.471ArgAsp: 3.471 ± 0.042	4.17ArgGlu: 4.17 ± 0.049	2.383ArgPhe: 2.383 ± 0.024	4.846ArgGly: 4.846 ± 0.05	1.641ArgHis: 1.641 ± 0.02	3.05ArgIle: 3.05 ± 0.029	3.344ArgLys: 3.344 ± 0.032	5.984ArgLeu: 5.984 ± 0.046	1.393ArgMet: 1.393 ± 0.019	2.05ArgAsn: 2.05 ± 0.022	4.334ArgPro: 4.334 ± 0.048	2.214ArgGln: 2.214 ± 0.025	6.286ArgArg: 6.286 ± 0.055	5.429ArgSer: 5.429 ± 0.049	3.683ArgThr: 3.683 ± 0.03	4.185ArgVal: 4.185 ± 0.033	0.996ArgTrp: 0.996 ± 0.018	1.372ArgTyr: 1.372 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	7.923SerAla: 7.923 ± 0.052	1.15SerCys: 1.15 ± 0.019	4.131SerAsp: 4.131 ± 0.034	3.804SerGlu: 3.804 ± 0.037	2.939SerPhe: 2.939 ± 0.025	5.778SerGly: 5.778 ± 0.054	1.927SerHis: 1.927 ± 0.023	3.658SerIle: 3.658 ± 0.038	3.129SerLys: 3.129 ± 0.031	7.399SerLeu: 7.399 ± 0.046	1.45SerMet: 1.45 ± 0.016	2.536SerAsn: 2.536 ± 0.031	6.793SerPro: 6.793 ± 0.056	2.553SerGln: 2.553 ± 0.026	5.33SerArg: 5.33 ± 0.045	9.015SerSer: 9.015 ± 0.073	5.778SerThr: 5.778 ± 0.049	4.912SerVal: 4.912 ± 0.044	1.013SerTrp: 1.013 ± 0.017	1.644SerTyr: 1.644 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	5.829ThrAla: 5.829 ± 0.047	0.891ThrCys: 0.891 ± 0.014	2.765ThrAsp: 2.765 ± 0.028	2.75ThrGlu: 2.75 ± 0.028	2.225ThrPhe: 2.225 ± 0.026	3.913ThrGly: 3.913 ± 0.041	1.379ThrHis: 1.379 ± 0.019	2.84ThrIle: 2.84 ± 0.031	2.131ThrLys: 2.131 ± 0.026	5.715ThrLeu: 5.715 ± 0.038	1.041ThrMet: 1.041 ± 0.016	1.852ThrAsn: 1.852 ± 0.028	4.975ThrPro: 4.975 ± 0.043	1.7ThrGln: 1.7 ± 0.019	3.433ThrArg: 3.433 ± 0.034	5.488ThrSer: 5.488 ± 0.048	4.725ThrThr: 4.725 ± 0.141	3.895ThrVal: 3.895 ± 0.041	0.732ThrTrp: 0.732 ± 0.012	1.321ThrTyr: 1.321 ± 0.023	0.0ThrXaa: 0.0 ± 0.0
Val	6.881ValAla: 6.881 ± 0.045	1.049ValCys: 1.049 ± 0.018	4.04ValAsp: 4.04 ± 0.036	4.325ValGlu: 4.325 ± 0.045	2.348ValPhe: 2.348 ± 0.024	4.943ValGly: 4.943 ± 0.039	1.576ValHis: 1.576 ± 0.023	2.726ValIle: 2.726 ± 0.027	2.702ValLys: 2.702 ± 0.026	5.731ValLeu: 5.731 ± 0.039	1.211ValMet: 1.211 ± 0.017	2.016ValAsn: 2.016 ± 0.028	4.212ValPro: 4.212 ± 0.034	2.12ValGln: 2.12 ± 0.024	4.212ValArg: 4.212 ± 0.036	4.766ValSer: 4.766 ± 0.034	3.529ValThr: 3.529 ± 0.037	5.151ValVal: 5.151 ± 0.045	0.838ValTrp: 0.838 ± 0.016	1.406ValTyr: 1.406 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.105TrpAla: 1.105 ± 0.018	0.212TrpCys: 0.212 ± 0.007	0.781TrpAsp: 0.781 ± 0.014	0.774TrpGlu: 0.774 ± 0.015	0.475TrpPhe: 0.475 ± 0.011	0.966TrpGly: 0.966 ± 0.018	0.28TrpHis: 0.28 ± 0.009	0.638TrpIle: 0.638 ± 0.013	0.66TrpLys: 0.66 ± 0.015	1.08TrpLeu: 1.08 ± 0.019	0.325TrpMet: 0.325 ± 0.009	0.502TrpAsn: 0.502 ± 0.012	0.571TrpPro: 0.571 ± 0.012	0.417TrpGln: 0.417 ± 0.009	1.007TrpArg: 1.007 ± 0.016	0.998TrpSer: 0.998 ± 0.017	0.854TrpThr: 0.854 ± 0.013	0.841TrpVal: 0.841 ± 0.013	0.249TrpTrp: 0.249 ± 0.008	0.274TrpTyr: 0.274 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.8TyrAla: 1.8 ± 0.022	0.397TyrCys: 0.397 ± 0.01	1.231TyrAsp: 1.231 ± 0.021	1.168TyrGlu: 1.168 ± 0.019	0.902TyrPhe: 0.902 ± 0.016	1.614TyrGly: 1.614 ± 0.029	0.584TyrHis: 0.584 ± 0.013	1.001TyrIle: 1.001 ± 0.015	0.834TyrLys: 0.834 ± 0.015	2.192TyrLeu: 2.192 ± 0.022	0.441TyrMet: 0.441 ± 0.01	0.764TyrAsn: 0.764 ± 0.014	1.324TyrPro: 1.324 ± 0.019	0.752TyrGln: 0.752 ± 0.015	1.403TyrArg: 1.403 ± 0.018	1.616TyrSer: 1.616 ± 0.022	1.167TyrThr: 1.167 ± 0.022	1.417TyrVal: 1.417 ± 0.022	0.313TyrTrp: 0.313 ± 0.009	0.648TyrTyr: 0.648 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12137 proteins (4355336 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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