Amino acid dipepetide frequency for Potato leafroll virus (strain Potato/Scotland/strain 1/1984) (PLrV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.707AlaAla: 7.707 ± 1.208
0.266AlaCys: 0.266 ± 0.35
3.189AlaAsp: 3.189 ± 0.786
5.581AlaGlu: 5.581 ± 1.249
2.392AlaPhe: 2.392 ± 0.647
3.72AlaGly: 3.72 ± 0.552
1.86AlaHis: 1.86 ± 0.504
3.189AlaIle: 3.189 ± 1.086
4.252AlaLys: 4.252 ± 0.586
5.315AlaLeu: 5.315 ± 1.655
1.063AlaMet: 1.063 ± 0.483
1.86AlaAsn: 1.86 ± 0.438
5.049AlaPro: 5.049 ± 1.445
1.86AlaGln: 1.86 ± 0.869
4.518AlaArg: 4.518 ± 0.896
5.049AlaSer: 5.049 ± 1.082
7.175AlaThr: 7.175 ± 1.623
4.783AlaVal: 4.783 ± 1.149
0.531AlaTrp: 0.531 ± 0.406
3.986AlaTyr: 3.986 ± 0.784
0.0AlaXaa: 0.0 ± 0.0
Cys
0.266CysAla: 0.266 ± 0.203
0.0CysCys: 0.0 ± 0.0
0.266CysAsp: 0.266 ± 0.203
0.797CysGlu: 0.797 ± 0.493
0.0CysPhe: 0.0 ± 0.0
1.063CysGly: 1.063 ± 0.654
1.063CysHis: 1.063 ± 0.276
1.329CysIle: 1.329 ± 0.628
1.063CysLys: 1.063 ± 0.738
2.392CysLeu: 2.392 ± 0.929
0.0CysMet: 0.0 ± 0.0
1.063CysAsn: 1.063 ± 0.488
0.797CysPro: 0.797 ± 0.359
0.797CysGln: 0.797 ± 0.398
0.797CysArg: 0.797 ± 0.467
1.329CysSer: 1.329 ± 0.778
0.0CysThr: 0.0 ± 0.0
0.266CysVal: 0.266 ± 0.203
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.252AspAla: 4.252 ± 1.307
1.329AspCys: 1.329 ± 0.442
2.392AspAsp: 2.392 ± 0.385
3.189AspGlu: 3.189 ± 0.704
0.797AspPhe: 0.797 ± 0.378
4.783AspGly: 4.783 ± 1.729
0.797AspHis: 0.797 ± 0.493
1.594AspIle: 1.594 ± 0.41
1.594AspLys: 1.594 ± 0.731
1.594AspLeu: 1.594 ± 0.529
1.86AspMet: 1.86 ± 0.387
1.063AspAsn: 1.063 ± 0.538
2.126AspPro: 2.126 ± 0.629
2.126AspGln: 2.126 ± 0.629
2.657AspArg: 2.657 ± 0.548
3.72AspSer: 3.72 ± 1.136
0.266AspThr: 0.266 ± 0.203
1.063AspVal: 1.063 ± 0.642
1.86AspTrp: 1.86 ± 0.598
2.392AspTyr: 2.392 ± 0.488
0.0AspXaa: 0.0 ± 0.0
Glu
8.238GluAla: 8.238 ± 1.972
1.594GluCys: 1.594 ± 0.644
3.986GluAsp: 3.986 ± 0.649
5.049GluGlu: 5.049 ± 1.557
2.126GluPhe: 2.126 ± 1.177
6.378GluGly: 6.378 ± 1.07
2.392GluHis: 2.392 ± 0.566
1.063GluIle: 1.063 ± 0.276
4.252GluLys: 4.252 ± 0.992
6.644GluLeu: 6.644 ± 1.419
0.797GluMet: 0.797 ± 0.32
4.518GluAsn: 4.518 ± 1.362
1.86GluPro: 1.86 ± 0.869
1.86GluGln: 1.86 ± 0.546
4.518GluArg: 4.518 ± 0.906
1.594GluSer: 1.594 ± 0.464
1.329GluThr: 1.329 ± 0.461
1.594GluVal: 1.594 ± 0.718
1.329GluTrp: 1.329 ± 0.407
2.657GluTyr: 2.657 ± 0.682
0.0GluXaa: 0.0 ± 0.0
Phe
1.594PheAla: 1.594 ± 0.579
0.266PheCys: 0.266 ± 0.203
1.329PheAsp: 1.329 ± 0.348
1.594PheGlu: 1.594 ± 0.422
1.594PhePhe: 1.594 ± 0.41
2.126PheGly: 2.126 ± 0.505
0.531PheHis: 0.531 ± 0.321
1.063PheIle: 1.063 ± 0.276
3.189PheLys: 3.189 ± 0.482
3.72PheLeu: 3.72 ± 1.16
1.063PheMet: 1.063 ± 0.488
1.594PheAsn: 1.594 ± 0.464
2.126PhePro: 2.126 ± 0.927
2.126PheGln: 2.126 ± 0.605
2.392PheArg: 2.392 ± 0.387
4.518PheSer: 4.518 ± 0.973
2.126PheThr: 2.126 ± 0.757
2.657PheVal: 2.657 ± 1.056
0.531PheTrp: 0.531 ± 0.244
0.531PheTyr: 0.531 ± 0.244
0.0PheXaa: 0.0 ± 0.0
Gly
4.518GlyAla: 4.518 ± 1.389
0.797GlyCys: 0.797 ± 0.398
2.126GlyAsp: 2.126 ± 0.65
2.657GlyGlu: 2.657 ± 1.004
4.252GlyPhe: 4.252 ± 1.889
4.783GlyGly: 4.783 ± 1.418
1.594GlyHis: 1.594 ± 0.496
1.86GlyIle: 1.86 ± 0.438
2.126GlyLys: 2.126 ± 0.683
4.252GlyLeu: 4.252 ± 1.571
1.063GlyMet: 1.063 ± 0.669
5.315GlyAsn: 5.315 ± 1.364
3.455GlyPro: 3.455 ± 0.713
2.657GlyGln: 2.657 ± 0.663
5.581GlyArg: 5.581 ± 0.727
8.504GlySer: 8.504 ± 2.622
5.315GlyThr: 5.315 ± 1.209
4.783GlyVal: 4.783 ± 1.16
0.797GlyTrp: 0.797 ± 0.493
3.189GlyTyr: 3.189 ± 0.506
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.329HisCys: 1.329 ± 0.442
1.063HisAsp: 1.063 ± 0.435
2.392HisGlu: 2.392 ± 0.585
1.86HisPhe: 1.86 ± 0.442
0.797HisGly: 0.797 ± 0.271
0.797HisHis: 0.797 ± 0.398
0.531HisIle: 0.531 ± 0.406
0.797HisLys: 0.797 ± 0.61
2.923HisLeu: 2.923 ± 0.662
0.266HisMet: 0.266 ± 0.192
0.0HisAsn: 0.0 ± 0.0
2.923HisPro: 2.923 ± 0.464
1.329HisGln: 1.329 ± 0.665
0.531HisArg: 0.531 ± 0.376
1.329HisSer: 1.329 ± 0.729
0.531HisThr: 0.531 ± 0.321
0.797HisVal: 0.797 ± 0.374
0.0HisTrp: 0.0 ± 0.0
0.266HisTyr: 0.266 ± 0.35
0.0HisXaa: 0.0 ± 0.0
Ile
4.783IleAla: 4.783 ± 1.928
0.531IleCys: 0.531 ± 0.7
0.531IleAsp: 0.531 ± 0.244
2.923IleGlu: 2.923 ± 0.556
0.797IlePhe: 0.797 ± 0.398
1.86IleGly: 1.86 ± 0.651
0.266IleHis: 0.266 ± 0.203
2.392IleIle: 2.392 ± 0.663
1.329IleLys: 1.329 ± 0.625
3.189IleLeu: 3.189 ± 1.11
0.266IleMet: 0.266 ± 0.203
1.86IleAsn: 1.86 ± 0.544
4.252IlePro: 4.252 ± 0.817
3.189IleGln: 3.189 ± 1.18
2.392IleArg: 2.392 ± 0.582
3.189IleSer: 3.189 ± 0.942
4.252IleThr: 4.252 ± 1.067
1.063IleVal: 1.063 ± 1.015
1.063IleTrp: 1.063 ± 0.488
1.594IleTyr: 1.594 ± 0.806
0.0IleXaa: 0.0 ± 0.0
Lys
4.252LysAla: 4.252 ± 0.958
0.531LysCys: 0.531 ± 0.406
1.86LysAsp: 1.86 ± 0.915
3.72LysGlu: 3.72 ± 0.879
1.594LysPhe: 1.594 ± 0.524
6.112LysGly: 6.112 ± 1.714
0.531LysHis: 0.531 ± 0.321
2.392LysIle: 2.392 ± 0.63
2.126LysLys: 2.126 ± 0.797
5.315LysLeu: 5.315 ± 1.527
2.126LysMet: 2.126 ± 0.675
2.923LysAsn: 2.923 ± 0.866
5.049LysPro: 5.049 ± 1.345
1.594LysGln: 1.594 ± 0.663
4.252LysArg: 4.252 ± 0.988
4.252LysSer: 4.252 ± 0.758
5.846LysThr: 5.846 ± 0.884
2.126LysVal: 2.126 ± 0.708
0.531LysTrp: 0.531 ± 0.406
1.594LysTyr: 1.594 ± 0.846
0.0LysXaa: 0.0 ± 0.0
Leu
2.126LeuAla: 2.126 ± 1.167
3.189LeuCys: 3.189 ± 1.506
3.455LeuAsp: 3.455 ± 1.166
9.833LeuGlu: 9.833 ± 1.138
3.986LeuPhe: 3.986 ± 0.984
3.986LeuGly: 3.986 ± 0.741
1.86LeuHis: 1.86 ± 0.984
3.189LeuIle: 3.189 ± 0.677
5.315LeuLys: 5.315 ± 0.851
8.504LeuLeu: 8.504 ± 3.542
1.329LeuMet: 1.329 ± 1.233
2.923LeuAsn: 2.923 ± 0.945
2.657LeuPro: 2.657 ± 0.941
7.175LeuGln: 7.175 ± 2.204
4.518LeuArg: 4.518 ± 1.305
4.252LeuSer: 4.252 ± 1.155
7.175LeuThr: 7.175 ± 1.305
4.518LeuVal: 4.518 ± 1.109
2.923LeuTrp: 2.923 ± 0.403
2.126LeuTyr: 2.126 ± 0.818
0.0LeuXaa: 0.0 ± 0.0
Met
1.063MetAla: 1.063 ± 0.355
0.531MetCys: 0.531 ± 0.244
0.266MetAsp: 0.266 ± 0.207
1.329MetGlu: 1.329 ± 0.508
0.531MetPhe: 0.531 ± 0.244
0.531MetGly: 0.531 ± 0.376
0.0MetHis: 0.0 ± 0.0
1.329MetIle: 1.329 ± 0.538
0.531MetLys: 0.531 ± 0.321
2.923MetLeu: 2.923 ± 0.707
0.0MetMet: 0.0 ± 0.0
0.531MetAsn: 0.531 ± 0.244
0.266MetPro: 0.266 ± 0.443
0.531MetGln: 0.531 ± 0.321
1.594MetArg: 1.594 ± 1.078
4.518MetSer: 4.518 ± 1.314
0.797MetThr: 0.797 ± 0.494
1.594MetVal: 1.594 ± 0.717
0.0MetTrp: 0.0 ± 0.0
0.531MetTyr: 0.531 ± 0.321
0.0MetXaa: 0.0 ± 0.0
Asn
2.657AsnAla: 2.657 ± 0.646
1.063AsnCys: 1.063 ± 0.446
1.594AsnAsp: 1.594 ± 0.547
0.531AsnGlu: 0.531 ± 0.244
1.594AsnPhe: 1.594 ± 0.6
3.455AsnGly: 3.455 ± 1.054
0.531AsnHis: 0.531 ± 0.376
1.329AsnIle: 1.329 ± 0.468
4.252AsnLys: 4.252 ± 0.86
2.392AsnLeu: 2.392 ± 0.718
0.0AsnMet: 0.0 ± 0.0
0.531AsnAsn: 0.531 ± 0.378
2.657AsnPro: 2.657 ± 0.782
1.594AsnGln: 1.594 ± 0.483
3.455AsnArg: 3.455 ± 0.875
5.049AsnSer: 5.049 ± 1.302
2.657AsnThr: 2.657 ± 0.648
2.923AsnVal: 2.923 ± 0.959
1.594AsnTrp: 1.594 ± 0.41
3.189AsnTyr: 3.189 ± 0.506
0.0AsnXaa: 0.0 ± 0.0
Pro
5.581ProAla: 5.581 ± 0.878
0.0ProCys: 0.0 ± 0.0
1.063ProAsp: 1.063 ± 0.494
3.189ProGlu: 3.189 ± 0.806
1.329ProPhe: 1.329 ± 0.654
3.455ProGly: 3.455 ± 0.79
1.329ProHis: 1.329 ± 0.461
1.86ProIle: 1.86 ± 0.539
3.189ProLys: 3.189 ± 0.828
4.783ProLeu: 4.783 ± 1.37
2.126ProMet: 2.126 ± 0.711
2.126ProAsn: 2.126 ± 0.576
9.567ProPro: 9.567 ± 2.46
3.189ProGln: 3.189 ± 0.996
5.315ProArg: 5.315 ± 1.721
7.175ProSer: 7.175 ± 0.977
5.315ProThr: 5.315 ± 1.521
2.657ProVal: 2.657 ± 0.372
0.0ProTrp: 0.0 ± 0.0
0.266ProTyr: 0.266 ± 0.203
0.0ProXaa: 0.0 ± 0.0
Gln
3.986GlnAla: 3.986 ± 0.661
0.531GlnCys: 0.531 ± 0.368
1.063GlnAsp: 1.063 ± 0.276
2.392GlnGlu: 2.392 ± 0.951
1.329GlnPhe: 1.329 ± 0.442
2.657GlnGly: 2.657 ± 0.925
1.063GlnHis: 1.063 ± 0.655
1.86GlnIle: 1.86 ± 0.694
3.986GlnLys: 3.986 ± 0.832
2.392GlnLeu: 2.392 ± 0.944
0.266GlnMet: 0.266 ± 0.529
2.923GlnAsn: 2.923 ± 0.693
5.315GlnPro: 5.315 ± 2.004
2.126GlnGln: 2.126 ± 1.666
2.923GlnArg: 2.923 ± 1.988
3.72GlnSer: 3.72 ± 0.759
4.518GlnThr: 4.518 ± 0.829
1.063GlnVal: 1.063 ± 0.501
2.126GlnTrp: 2.126 ± 0.672
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.189ArgAla: 3.189 ± 0.829
0.0ArgCys: 0.0 ± 0.0
1.86ArgAsp: 1.86 ± 0.895
5.315ArgGlu: 5.315 ± 0.804
2.392ArgPhe: 2.392 ± 0.376
4.518ArgGly: 4.518 ± 0.896
2.392ArgHis: 2.392 ± 0.738
3.455ArgIle: 3.455 ± 0.804
3.986ArgLys: 3.986 ± 1.991
5.846ArgLeu: 5.846 ± 1.219
1.86ArgMet: 1.86 ± 0.885
3.455ArgAsn: 3.455 ± 0.555
1.86ArgPro: 1.86 ± 1.373
2.126ArgGln: 2.126 ± 0.66
8.238ArgArg: 8.238 ± 4.384
4.783ArgSer: 4.783 ± 1.772
2.126ArgThr: 2.126 ± 0.477
4.252ArgVal: 4.252 ± 0.572
0.266ArgTrp: 0.266 ± 0.203
0.797ArgTyr: 0.797 ± 0.61
0.0ArgXaa: 0.0 ± 0.0
Ser
7.175SerAla: 7.175 ± 2.353
1.329SerCys: 1.329 ± 0.731
6.112SerAsp: 6.112 ± 1.798
6.112SerGlu: 6.112 ± 1.047
3.189SerPhe: 3.189 ± 0.957
7.441SerGly: 7.441 ± 0.575
0.797SerHis: 0.797 ± 0.398
5.315SerIle: 5.315 ± 1.076
4.783SerLys: 4.783 ± 0.649
11.427SerLeu: 11.427 ± 1.029
1.594SerMet: 1.594 ± 0.881
1.063SerAsn: 1.063 ± 0.301
4.252SerPro: 4.252 ± 1.071
2.657SerGln: 2.657 ± 1.304
2.657SerArg: 2.657 ± 1.112
10.896SerSer: 10.896 ± 2.601
6.378SerThr: 6.378 ± 0.995
5.846SerVal: 5.846 ± 2.058
2.657SerTrp: 2.657 ± 0.88
2.923SerTyr: 2.923 ± 0.455
0.0SerXaa: 0.0 ± 0.0
Thr
6.378ThrAla: 6.378 ± 1.935
0.0ThrCys: 0.0 ± 0.0
4.783ThrAsp: 4.783 ± 1.104
1.594ThrGlu: 1.594 ± 0.904
2.923ThrPhe: 2.923 ± 0.849
4.252ThrGly: 4.252 ± 0.716
0.531ThrHis: 0.531 ± 0.582
4.518ThrIle: 4.518 ± 1.328
2.392ThrLys: 2.392 ± 0.788
5.846ThrLeu: 5.846 ± 1.412
0.797ThrMet: 0.797 ± 0.38
3.455ThrAsn: 3.455 ± 0.943
4.518ThrPro: 4.518 ± 1.709
4.252ThrGln: 4.252 ± 0.566
0.531ThrArg: 0.531 ± 0.406
9.035ThrSer: 9.035 ± 1.336
2.923ThrThr: 2.923 ± 0.658
3.986ThrVal: 3.986 ± 0.877
0.531ThrTrp: 0.531 ± 0.244
2.126ThrTyr: 2.126 ± 1.103
0.0ThrXaa: 0.0 ± 0.0
Val
1.86ValAla: 1.86 ± 0.553
0.0ValCys: 0.0 ± 0.0
2.657ValAsp: 2.657 ± 1.105
2.923ValGlu: 2.923 ± 0.785
2.392ValPhe: 2.392 ± 0.827
4.783ValGly: 4.783 ± 0.875
0.266ValHis: 0.266 ± 0.203
2.392ValIle: 2.392 ± 0.944
4.783ValLys: 4.783 ± 0.827
3.189ValLeu: 3.189 ± 0.956
1.329ValMet: 1.329 ± 0.442
2.392ValAsn: 2.392 ± 0.981
3.986ValPro: 3.986 ± 0.585
2.657ValGln: 2.657 ± 0.85
1.86ValArg: 1.86 ± 0.746
6.644ValSer: 6.644 ± 0.905
2.923ValThr: 2.923 ± 0.773
2.657ValVal: 2.657 ± 1.21
0.266ValTrp: 0.266 ± 0.529
0.797ValTyr: 0.797 ± 0.958
0.0ValXaa: 0.0 ± 0.0
Trp
2.657TrpAla: 2.657 ± 1.096
0.0TrpCys: 0.0 ± 0.0
0.531TrpAsp: 0.531 ± 0.321
0.531TrpGlu: 0.531 ± 0.244
0.531TrpPhe: 0.531 ± 0.244
1.063TrpGly: 1.063 ± 0.752
0.531TrpHis: 0.531 ± 0.368
0.0TrpIle: 0.0 ± 0.0
1.329TrpLys: 1.329 ± 0.677
1.86TrpLeu: 1.86 ± 0.606
0.797TrpMet: 0.797 ± 0.398
1.063TrpAsn: 1.063 ± 0.276
0.797TrpPro: 0.797 ± 0.271
0.0TrpGln: 0.0 ± 0.0
2.392TrpArg: 2.392 ± 0.865
1.594TrpSer: 1.594 ± 0.341
1.86TrpThr: 1.86 ± 0.404
0.266TrpVal: 0.266 ± 0.203
0.0TrpTrp: 0.0 ± 0.0
0.797TrpTyr: 0.797 ± 0.591
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.063TyrAla: 1.063 ± 0.488
0.0TyrCys: 0.0 ± 0.0
1.329TyrAsp: 1.329 ± 0.427
2.126TyrGlu: 2.126 ± 0.615
1.063TyrPhe: 1.063 ± 0.397
1.86TyrGly: 1.86 ± 0.387
1.329TyrHis: 1.329 ± 0.448
1.063TyrIle: 1.063 ± 0.301
3.72TyrLys: 3.72 ± 1.509
0.531TyrLeu: 0.531 ± 0.376
0.531TyrMet: 0.531 ± 0.321
2.392TyrAsn: 2.392 ± 0.673
0.0TyrPro: 0.0 ± 0.0
2.392TyrGln: 2.392 ± 1.044
1.594TyrArg: 1.594 ± 0.601
3.455TyrSer: 3.455 ± 0.757
1.86TyrThr: 1.86 ± 0.506
1.86TyrVal: 1.86 ± 0.388
1.594TyrTrp: 1.594 ± 0.478
1.86TyrTyr: 1.86 ± 0.506
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (3764 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski