Amino acid dipepetide frequency for Wenling tombus-like virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.03AlaAla: 10.03 ± 3.61
1.003AlaCys: 1.003 ± 0.99
0.0AlaAsp: 0.0 ± 0.0
4.012AlaGlu: 4.012 ± 1.448
2.006AlaPhe: 2.006 ± 0.672
1.003AlaGly: 1.003 ± 0.99
6.018AlaHis: 6.018 ± 1.586
2.006AlaIle: 2.006 ± 0.672
7.021AlaLys: 7.021 ± 0.412
8.024AlaLeu: 8.024 ± 1.762
0.0AlaMet: 0.0 ± 0.565
0.0AlaAsn: 0.0 ± 0.0
1.003AlaPro: 1.003 ± 0.874
2.006AlaGln: 2.006 ± 0.741
4.012AlaArg: 4.012 ± 1.602
10.03AlaSer: 10.03 ± 2.468
4.012AlaThr: 4.012 ± 1.251
2.006AlaVal: 2.006 ± 1.385
0.0AlaTrp: 0.0 ± 0.0
4.012AlaTyr: 4.012 ± 1.645
0.0AlaXaa: 0.0 ± 0.0
Cys
1.003CysAla: 1.003 ± 0.99
1.003CysCys: 1.003 ± 0.99
0.0CysAsp: 0.0 ± 0.0
1.003CysGlu: 1.003 ± 0.99
1.003CysPhe: 1.003 ± 0.693
6.018CysGly: 6.018 ± 5.94
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.003CysLys: 1.003 ± 0.693
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.003CysAsn: 1.003 ± 0.99
1.003CysPro: 1.003 ± 0.99
1.003CysGln: 1.003 ± 0.693
3.009CysArg: 3.009 ± 2.97
1.003CysSer: 1.003 ± 0.693
2.006CysThr: 2.006 ± 1.98
4.012CysVal: 4.012 ± 0.176
0.0CysTrp: 0.0 ± 0.0
1.003CysTyr: 1.003 ± 0.693
0.0CysXaa: 0.0 ± 0.0
Asp
7.021AspAla: 7.021 ± 2.459
2.006AspCys: 2.006 ± 0.741
5.015AspAsp: 5.015 ± 0.714
3.009AspGlu: 3.009 ± 0.542
2.006AspPhe: 2.006 ± 1.385
6.018AspGly: 6.018 ± 2.076
2.006AspHis: 2.006 ± 0.741
3.009AspIle: 3.009 ± 1.048
1.003AspLys: 1.003 ± 0.99
3.009AspLeu: 3.009 ± 1.396
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
1.003AspPro: 1.003 ± 0.693
3.009AspGln: 3.009 ± 1.892
4.012AspArg: 4.012 ± 0.176
6.018AspSer: 6.018 ± 1.544
2.006AspThr: 2.006 ± 1.231
5.015AspVal: 5.015 ± 0.714
1.003AspTrp: 1.003 ± 0.693
5.015AspTyr: 5.015 ± 2.297
0.0AspXaa: 0.0 ± 0.0
Glu
1.003GluAla: 1.003 ± 0.693
1.003GluCys: 1.003 ± 0.693
4.012GluAsp: 4.012 ± 1.448
3.009GluGlu: 3.009 ± 2.057
2.006GluPhe: 2.006 ± 1.385
1.003GluGly: 1.003 ± 0.99
1.003GluHis: 1.003 ± 0.693
3.009GluIle: 3.009 ± 2.621
4.012GluLys: 4.012 ± 0.176
6.018GluLeu: 6.018 ± 0.842
1.003GluMet: 1.003 ± 0.874
2.006GluAsn: 2.006 ± 1.385
2.006GluPro: 2.006 ± 0.672
0.0GluGln: 0.0 ± 0.0
5.015GluArg: 5.015 ± 0.853
2.006GluSer: 2.006 ± 1.385
3.009GluThr: 3.009 ± 0.542
3.009GluVal: 3.009 ± 1.892
1.003GluTrp: 1.003 ± 0.874
1.003GluTyr: 1.003 ± 0.693
0.0GluXaa: 0.0 ± 0.0
Phe
4.012PheAla: 4.012 ± 1.645
4.012PheCys: 4.012 ± 1.482
1.003PheAsp: 1.003 ± 0.693
1.003PheGlu: 1.003 ± 0.693
0.0PhePhe: 0.0 ± 0.0
3.009PheGly: 3.009 ± 1.048
2.006PheHis: 2.006 ± 1.747
2.006PheIle: 2.006 ± 0.672
1.003PheLys: 1.003 ± 0.693
6.018PheLeu: 6.018 ± 2.016
1.003PheMet: 1.003 ± 0.693
2.006PheAsn: 2.006 ± 0.672
1.003PhePro: 1.003 ± 0.693
1.003PheGln: 1.003 ± 0.874
5.015PheArg: 5.015 ± 2.421
5.015PheSer: 5.015 ± 2.297
0.0PheThr: 0.0 ± 0.0
5.015PheVal: 5.015 ± 3.463
2.006PheTrp: 2.006 ± 0.672
1.003PheTyr: 1.003 ± 0.693
0.0PheXaa: 0.0 ± 0.0
Gly
3.009GlyAla: 3.009 ± 0.542
4.012GlyCys: 4.012 ± 1.482
5.015GlyAsp: 5.015 ± 1.666
1.003GlyGlu: 1.003 ± 0.693
2.006GlyPhe: 2.006 ± 1.385
4.012GlyGly: 4.012 ± 2.984
2.006GlyHis: 2.006 ± 0.741
4.012GlyIle: 4.012 ± 0.176
3.009GlyLys: 3.009 ± 2.97
5.015GlyLeu: 5.015 ± 0.853
1.003GlyMet: 1.003 ± 0.99
4.012GlyAsn: 4.012 ± 1.602
4.012GlyPro: 4.012 ± 2.463
2.006GlyGln: 2.006 ± 1.231
7.021GlyArg: 7.021 ± 1.206
6.018GlySer: 6.018 ± 3.212
4.012GlyThr: 4.012 ± 1.251
4.012GlyVal: 4.012 ± 2.23
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
4.012HisAla: 4.012 ± 1.482
0.0HisCys: 0.0 ± 0.0
2.006HisAsp: 2.006 ± 1.747
1.003HisGlu: 1.003 ± 0.693
2.006HisPhe: 2.006 ± 0.741
4.012HisGly: 4.012 ± 1.645
2.006HisHis: 2.006 ± 0.672
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.006HisLeu: 2.006 ± 0.741
1.003HisMet: 1.003 ± 0.693
2.006HisAsn: 2.006 ± 0.672
0.0HisPro: 0.0 ± 0.0
1.003HisGln: 1.003 ± 0.99
7.021HisArg: 7.021 ± 0.412
5.015HisSer: 5.015 ± 3.942
2.006HisThr: 2.006 ± 1.747
1.003HisVal: 1.003 ± 0.99
1.003HisTrp: 1.003 ± 0.693
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.012IleAla: 4.012 ± 1.344
1.003IleCys: 1.003 ± 0.874
0.0IleAsp: 0.0 ± 0.0
6.018IleGlu: 6.018 ± 2.967
0.0IlePhe: 0.0 ± 0.0
0.0IleGly: 0.0 ± 0.0
1.003IleHis: 1.003 ± 0.99
1.003IleIle: 1.003 ± 0.99
0.0IleLys: 0.0 ± 0.0
5.015IleLeu: 5.015 ± 1.666
1.003IleMet: 1.003 ± 0.693
4.012IleAsn: 4.012 ± 0.176
5.015IlePro: 5.015 ± 1.619
2.006IleGln: 2.006 ± 0.672
2.006IleArg: 2.006 ± 0.741
4.012IleSer: 4.012 ± 0.176
1.003IleThr: 1.003 ± 0.874
2.006IleVal: 2.006 ± 1.385
1.003IleTrp: 1.003 ± 0.693
2.006IleTyr: 2.006 ± 1.231
0.0IleXaa: 0.0 ± 0.0
Lys
2.006LysAla: 2.006 ± 1.231
0.0LysCys: 0.0 ± 0.0
5.015LysAsp: 5.015 ± 0.853
1.003LysGlu: 1.003 ± 0.99
5.015LysPhe: 5.015 ± 0.853
3.009LysGly: 3.009 ± 2.078
0.0LysHis: 0.0 ± 0.0
1.003LysIle: 1.003 ± 0.693
4.012LysLys: 4.012 ± 1.251
4.012LysLeu: 4.012 ± 1.645
0.0LysMet: 0.0 ± 0.0
1.003LysAsn: 1.003 ± 0.874
4.012LysPro: 4.012 ± 0.176
2.006LysGln: 2.006 ± 0.672
2.006LysArg: 2.006 ± 0.672
3.009LysSer: 3.009 ± 1.606
4.012LysThr: 4.012 ± 2.463
2.006LysVal: 2.006 ± 1.385
0.0LysTrp: 0.0 ± 0.0
2.006LysTyr: 2.006 ± 1.385
0.0LysXaa: 0.0 ± 0.0
Leu
6.018LeuAla: 6.018 ± 2.076
1.003LeuCys: 1.003 ± 0.99
6.018LeuAsp: 6.018 ± 1.586
4.012LeuGlu: 4.012 ± 1.645
6.018LeuPhe: 6.018 ± 0.644
6.018LeuGly: 6.018 ± 1.544
3.009LeuHis: 3.009 ± 1.048
5.015LeuIle: 5.015 ± 2.239
2.006LeuLys: 2.006 ± 0.741
7.021LeuLeu: 7.021 ± 2.671
2.006LeuMet: 2.006 ± 0.672
7.021LeuAsn: 7.021 ± 3.645
2.006LeuPro: 2.006 ± 0.741
2.006LeuGln: 2.006 ± 1.231
6.018LeuArg: 6.018 ± 2.016
9.027LeuSer: 9.027 ± 1.018
3.009LeuThr: 3.009 ± 0.542
4.012LeuVal: 4.012 ± 0.176
0.0LeuTrp: 0.0 ± 0.0
2.006LeuTyr: 2.006 ± 1.385
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
2.006MetAsp: 2.006 ± 0.741
0.0MetGlu: 0.0 ± 0.0
4.012MetPhe: 4.012 ± 2.771
1.003MetGly: 1.003 ± 0.874
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.006MetLys: 2.006 ± 1.747
3.009MetLeu: 3.009 ± 1.396
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
3.009MetPro: 3.009 ± 2.621
0.0MetGln: 0.0 ± 0.0
2.006MetArg: 2.006 ± 0.672
1.003MetSer: 1.003 ± 0.693
2.006MetThr: 2.006 ± 0.672
2.006MetVal: 2.006 ± 0.741
1.003MetTrp: 1.003 ± 0.693
1.003MetTyr: 1.003 ± 0.693
0.0MetXaa: 0.0 ± 0.0
Asn
1.003AsnAla: 1.003 ± 0.693
1.003AsnCys: 1.003 ± 0.693
2.006AsnAsp: 2.006 ± 0.672
1.003AsnGlu: 1.003 ± 0.693
0.0AsnPhe: 0.0 ± 0.0
1.003AsnGly: 1.003 ± 0.99
1.003AsnHis: 1.003 ± 0.693
2.006AsnIle: 2.006 ± 0.741
1.003AsnLys: 1.003 ± 0.693
3.009AsnLeu: 3.009 ± 1.038
1.003AsnMet: 1.003 ± 0.693
1.003AsnAsn: 1.003 ± 0.693
3.009AsnPro: 3.009 ± 1.396
1.003AsnGln: 1.003 ± 0.874
7.021AsnArg: 7.021 ± 2.236
2.006AsnSer: 2.006 ± 0.741
2.006AsnThr: 2.006 ± 1.385
1.003AsnVal: 1.003 ± 0.99
3.009AsnTrp: 3.009 ± 1.396
2.006AsnTyr: 2.006 ± 1.747
0.0AsnXaa: 0.0 ± 0.0
Pro
3.009ProAla: 3.009 ± 0.542
0.0ProCys: 0.0 ± 0.0
3.009ProAsp: 3.009 ± 1.048
2.006ProGlu: 2.006 ± 0.672
1.003ProPhe: 1.003 ± 0.693
3.009ProGly: 3.009 ± 2.057
1.003ProHis: 1.003 ± 0.874
4.012ProIle: 4.012 ± 1.251
2.006ProLys: 2.006 ± 0.672
4.012ProLeu: 4.012 ± 0.176
1.003ProMet: 1.003 ± 0.874
2.006ProAsn: 2.006 ± 0.672
3.009ProPro: 3.009 ± 2.078
0.0ProGln: 0.0 ± 0.0
7.021ProArg: 7.021 ± 3.003
3.009ProSer: 3.009 ± 0.542
2.006ProThr: 2.006 ± 1.747
8.024ProVal: 8.024 ± 2.688
0.0ProTrp: 0.0 ± 0.0
3.009ProTyr: 3.009 ± 2.078
0.0ProXaa: 0.0 ± 0.0
Gln
2.006GlnAla: 2.006 ± 0.672
0.0GlnCys: 0.0 ± 0.0
3.009GlnAsp: 3.009 ± 1.396
1.003GlnGlu: 1.003 ± 0.874
1.003GlnPhe: 1.003 ± 0.874
1.003GlnGly: 1.003 ± 0.874
1.003GlnHis: 1.003 ± 0.693
0.0GlnIle: 0.0 ± 0.0
1.003GlnLys: 1.003 ± 0.874
2.006GlnLeu: 2.006 ± 0.741
1.003GlnMet: 1.003 ± 0.693
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
5.015GlnArg: 5.015 ± 3.505
5.015GlnSer: 5.015 ± 4.95
0.0GlnThr: 0.0 ± 0.0
1.003GlnVal: 1.003 ± 0.874
0.0GlnTrp: 0.0 ± 0.0
1.003GlnTyr: 1.003 ± 0.693
0.0GlnXaa: 0.0 ± 0.0
Arg
4.012ArgAla: 4.012 ± 2.771
5.015ArgCys: 5.015 ± 4.95
4.012ArgAsp: 4.012 ± 1.482
4.012ArgGlu: 4.012 ± 1.251
6.018ArgPhe: 6.018 ± 1.084
5.015ArgGly: 5.015 ± 0.961
7.021ArgHis: 7.021 ± 2.931
4.012ArgIle: 4.012 ± 1.344
3.009ArgLys: 3.009 ± 1.048
5.015ArgLeu: 5.015 ± 2.239
5.015ArgMet: 5.015 ± 0.974
1.003ArgAsn: 1.003 ± 0.99
4.012ArgPro: 4.012 ± 2.23
3.009ArgGln: 3.009 ± 1.396
13.039ArgArg: 13.039 ± 1.486
5.015ArgSer: 5.015 ± 0.714
9.027ArgThr: 9.027 ± 0.963
5.015ArgVal: 5.015 ± 0.714
2.006ArgTrp: 2.006 ± 0.672
4.012ArgTyr: 4.012 ± 1.602
0.0ArgXaa: 0.0 ± 0.0
Ser
3.009SerAla: 3.009 ± 1.606
4.012SerCys: 4.012 ± 3.96
8.024SerAsp: 8.024 ± 1.777
3.009SerGlu: 3.009 ± 1.606
5.015SerPhe: 5.015 ± 2.01
11.033SerGly: 11.033 ± 4.335
2.006SerHis: 2.006 ± 0.741
5.015SerIle: 5.015 ± 1.666
3.009SerLys: 3.009 ± 2.078
5.015SerLeu: 5.015 ± 2.297
3.009SerMet: 3.009 ± 1.179
2.006SerAsn: 2.006 ± 1.98
8.024SerPro: 8.024 ± 1.305
1.003SerGln: 1.003 ± 0.99
8.024SerArg: 8.024 ± 2.675
4.012SerSer: 4.012 ± 1.448
2.006SerThr: 2.006 ± 1.98
6.018SerVal: 6.018 ± 2.39
1.003SerTrp: 1.003 ± 0.99
2.006SerTyr: 2.006 ± 1.385
0.0SerXaa: 0.0 ± 0.0
Thr
5.015ThrAla: 5.015 ± 3.086
0.0ThrCys: 0.0 ± 0.0
1.003ThrAsp: 1.003 ± 0.99
3.009ThrGlu: 3.009 ± 0.542
1.003ThrPhe: 1.003 ± 0.693
2.006ThrGly: 2.006 ± 0.672
2.006ThrHis: 2.006 ± 1.98
1.003ThrIle: 1.003 ± 0.693
5.015ThrLys: 5.015 ± 0.714
6.018ThrLeu: 6.018 ± 1.586
0.0ThrMet: 0.0 ± 0.0
2.006ThrAsn: 2.006 ± 0.672
4.012ThrPro: 4.012 ± 2.984
1.003ThrGln: 1.003 ± 0.874
3.009ThrArg: 3.009 ± 2.057
3.009ThrSer: 3.009 ± 2.057
1.003ThrThr: 1.003 ± 0.99
2.006ThrVal: 2.006 ± 0.672
2.006ThrTrp: 2.006 ± 1.747
1.003ThrTyr: 1.003 ± 0.99
0.0ThrXaa: 0.0 ± 0.0
Val
5.015ValAla: 5.015 ± 0.714
0.0ValCys: 0.0 ± 0.0
6.018ValAsp: 6.018 ± 2.792
7.021ValGlu: 7.021 ± 2.652
2.006ValPhe: 2.006 ± 1.385
5.015ValGly: 5.015 ± 0.714
3.009ValHis: 3.009 ± 0.542
4.012ValIle: 4.012 ± 1.602
2.006ValLys: 2.006 ± 1.385
5.015ValLeu: 5.015 ± 0.961
2.006ValMet: 2.006 ± 0.672
1.003ValAsn: 1.003 ± 0.874
6.018ValPro: 6.018 ± 2.097
1.003ValGln: 1.003 ± 0.99
1.003ValArg: 1.003 ± 0.874
6.018ValSer: 6.018 ± 2.223
1.003ValThr: 1.003 ± 0.874
2.006ValVal: 2.006 ± 0.741
1.003ValTrp: 1.003 ± 0.693
2.006ValTyr: 2.006 ± 1.385
0.0ValXaa: 0.0 ± 0.0
Trp
1.003TrpAla: 1.003 ± 0.99
0.0TrpCys: 0.0 ± 0.0
3.009TrpAsp: 3.009 ± 2.078
0.0TrpGlu: 0.0 ± 0.0
3.009TrpPhe: 3.009 ± 1.396
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.003TrpLys: 1.003 ± 0.693
1.003TrpLeu: 1.003 ± 0.693
2.006TrpMet: 2.006 ± 0.672
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
2.006TrpGln: 2.006 ± 0.672
0.0TrpArg: 0.0 ± 0.0
2.006TrpSer: 2.006 ± 1.747
1.003TrpThr: 1.003 ± 0.874
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.009TyrAla: 3.009 ± 1.606
0.0TyrCys: 0.0 ± 0.0
1.003TyrAsp: 1.003 ± 0.693
0.0TyrGlu: 0.0 ± 0.0
2.006TyrPhe: 2.006 ± 0.672
2.006TyrGly: 2.006 ± 1.385
1.003TyrHis: 1.003 ± 0.693
1.003TyrIle: 1.003 ± 0.693
2.006TyrLys: 2.006 ± 1.385
3.009TyrLeu: 3.009 ± 2.078
1.003TyrMet: 1.003 ± 0.874
4.012TyrAsn: 4.012 ± 1.645
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
7.021TyrArg: 7.021 ± 1.131
4.012TyrSer: 4.012 ± 2.771
0.0TyrThr: 0.0 ± 0.0
3.009TyrVal: 3.009 ± 2.078
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (998 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski