Amino acid dipepetide frequency for Elsinoe australis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.496AlaAla: 9.496 ± 0.065	0.983AlaCys: 0.983 ± 0.017	4.422AlaAsp: 4.422 ± 0.035	5.255AlaGlu: 5.255 ± 0.042	3.118AlaPhe: 3.118 ± 0.033	6.458AlaGly: 6.458 ± 0.043	1.73AlaHis: 1.73 ± 0.02	4.109AlaIle: 4.109 ± 0.036	4.334AlaLys: 4.334 ± 0.038	7.626AlaLeu: 7.626 ± 0.051	1.995AlaMet: 1.995 ± 0.023	3.097AlaAsn: 3.097 ± 0.027	5.28AlaPro: 5.28 ± 0.056	3.708AlaGln: 3.708 ± 0.032	5.133AlaArg: 5.133 ± 0.036	7.66AlaSer: 7.66 ± 0.065	5.571AlaThr: 5.571 ± 0.049	5.532AlaVal: 5.532 ± 0.044	1.138AlaTrp: 1.138 ± 0.017	2.144AlaTyr: 2.144 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.891CysAla: 0.891 ± 0.016	0.184CysCys: 0.184 ± 0.006	0.577CysAsp: 0.577 ± 0.011	0.506CysGlu: 0.506 ± 0.012	0.477CysPhe: 0.477 ± 0.009	0.864CysGly: 0.864 ± 0.016	0.276CysHis: 0.276 ± 0.008	0.612CysIle: 0.612 ± 0.012	0.479CysLys: 0.479 ± 0.011	1.053CysLeu: 1.053 ± 0.017	0.231CysMet: 0.231 ± 0.007	0.378CysAsn: 0.378 ± 0.01	0.586CysPro: 0.586 ± 0.012	0.371CysGln: 0.371 ± 0.009	0.605CysArg: 0.605 ± 0.012	0.742CysSer: 0.742 ± 0.013	0.635CysThr: 0.635 ± 0.013	0.694CysVal: 0.694 ± 0.013	0.167CysTrp: 0.167 ± 0.008	0.303CysTyr: 0.303 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.946AspAla: 4.946 ± 0.034	0.569AspCys: 0.569 ± 0.013	4.194AspAsp: 4.194 ± 0.041	4.675AspGlu: 4.675 ± 0.044	2.247AspPhe: 2.247 ± 0.024	4.174AspGly: 4.174 ± 0.035	1.188AspHis: 1.188 ± 0.018	2.798AspIle: 2.798 ± 0.028	2.543AspLys: 2.543 ± 0.027	5.064AspLeu: 5.064 ± 0.035	1.334AspMet: 1.334 ± 0.018	1.827AspAsn: 1.827 ± 0.02	3.312AspPro: 3.312 ± 0.027	1.967AspGln: 1.967 ± 0.022	3.154AspArg: 3.154 ± 0.034	4.108AspSer: 4.108 ± 0.036	3.038AspThr: 3.038 ± 0.026	3.825AspVal: 3.825 ± 0.034	0.891AspTrp: 0.891 ± 0.015	1.593AspTyr: 1.593 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.412GluAla: 5.412 ± 0.04	0.517GluCys: 0.517 ± 0.011	4.388GluAsp: 4.388 ± 0.04	5.941GluGlu: 5.941 ± 0.06	1.724GluPhe: 1.724 ± 0.019	4.467GluGly: 4.467 ± 0.039	1.349GluHis: 1.349 ± 0.019	2.768GluIle: 2.768 ± 0.026	3.893GluLys: 3.893 ± 0.04	4.898GluLeu: 4.898 ± 0.045	1.542GluMet: 1.542 ± 0.019	2.012GluAsn: 2.012 ± 0.021	2.567GluPro: 2.567 ± 0.032	2.615GluGln: 2.615 ± 0.028	4.286GluArg: 4.286 ± 0.043	4.034GluSer: 4.034 ± 0.038	3.293GluThr: 3.293 ± 0.034	3.916GluVal: 3.916 ± 0.033	0.867GluTrp: 0.867 ± 0.013	1.58GluTyr: 1.58 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.154PheAla: 3.154 ± 0.031	0.482PheCys: 0.482 ± 0.011	2.266PheAsp: 2.266 ± 0.022	2.106PheGlu: 2.106 ± 0.024	1.534PhePhe: 1.534 ± 0.022	2.871PheGly: 2.871 ± 0.033	0.788PheHis: 0.788 ± 0.016	1.626PheIle: 1.626 ± 0.021	1.523PheLys: 1.523 ± 0.018	3.208PheLeu: 3.208 ± 0.032	0.747PheMet: 0.747 ± 0.013	1.402PheAsn: 1.402 ± 0.02	1.784PhePro: 1.784 ± 0.022	1.275PheGln: 1.275 ± 0.019	1.824PheArg: 1.824 ± 0.022	2.898PheSer: 2.898 ± 0.03	2.198PheThr: 2.198 ± 0.022	2.329PheVal: 2.329 ± 0.029	0.605PheTrp: 0.605 ± 0.012	1.06PheTyr: 1.06 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	5.803GlyAla: 5.803 ± 0.051	0.794GlyCys: 0.794 ± 0.014	3.76GlyAsp: 3.76 ± 0.035	4.144GlyGlu: 4.144 ± 0.036	2.804GlyPhe: 2.804 ± 0.029	6.645GlyGly: 6.645 ± 0.084	1.585GlyHis: 1.585 ± 0.023	3.398GlyIle: 3.398 ± 0.033	3.966GlyLys: 3.966 ± 0.032	6.15GlyLeu: 6.15 ± 0.041	1.844GlyMet: 1.844 ± 0.025	2.583GlyAsn: 2.583 ± 0.029	3.409GlyPro: 3.409 ± 0.03	3.015GlyGln: 3.015 ± 0.032	4.612GlyArg: 4.612 ± 0.039	5.975GlySer: 5.975 ± 0.051	4.332GlyThr: 4.332 ± 0.042	4.582GlyVal: 4.582 ± 0.038	1.219GlyTrp: 1.219 ± 0.019	2.181GlyTyr: 2.181 ± 0.027	0.0GlyXaa: 0.0 ± 0.0
His	1.84HisAla: 1.84 ± 0.021	0.265HisCys: 0.265 ± 0.009	1.331HisAsp: 1.331 ± 0.02	1.301HisGlu: 1.301 ± 0.016	0.884HisPhe: 0.884 ± 0.014	1.622HisGly: 1.622 ± 0.022	0.785HisHis: 0.785 ± 0.016	1.103HisIle: 1.103 ± 0.018	0.919HisLys: 0.919 ± 0.014	2.086HisLeu: 2.086 ± 0.025	0.456HisMet: 0.456 ± 0.01	0.82HisAsn: 0.82 ± 0.014	1.51HisPro: 1.51 ± 0.017	0.903HisGln: 0.903 ± 0.016	1.362HisArg: 1.362 ± 0.019	1.718HisSer: 1.718 ± 0.023	1.199HisThr: 1.199 ± 0.017	1.379HisVal: 1.379 ± 0.017	0.312HisTrp: 0.312 ± 0.008	0.638HisTyr: 0.638 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	4.155IleAla: 4.155 ± 0.034	0.643IleCys: 0.643 ± 0.012	2.802IleAsp: 2.802 ± 0.027	2.694IleGlu: 2.694 ± 0.026	1.799IlePhe: 1.799 ± 0.022	3.078IleGly: 3.078 ± 0.031	1.077IleHis: 1.077 ± 0.016	2.27IleIle: 2.27 ± 0.029	2.229IleLys: 2.229 ± 0.025	4.008IleLeu: 4.008 ± 0.042	0.98IleMet: 0.98 ± 0.016	1.762IleAsn: 1.762 ± 0.021	2.799IlePro: 2.799 ± 0.027	1.725IleGln: 1.725 ± 0.021	2.637IleArg: 2.637 ± 0.029	3.658IleSer: 3.658 ± 0.032	2.833IleThr: 2.833 ± 0.026	2.931IleVal: 2.931 ± 0.029	0.66IleTrp: 0.66 ± 0.013	1.294IleTyr: 1.294 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.533LysAla: 4.533 ± 0.038	0.446LysCys: 0.446 ± 0.011	3.063LysAsp: 3.063 ± 0.028	3.57LysGlu: 3.57 ± 0.038	1.41LysPhe: 1.41 ± 0.019	3.411LysGly: 3.411 ± 0.032	1.119LysHis: 1.119 ± 0.016	2.167LysIle: 2.167 ± 0.024	3.591LysLys: 3.591 ± 0.052	3.909LysLeu: 3.909 ± 0.034	1.046LysMet: 1.046 ± 0.016	1.684LysAsn: 1.684 ± 0.022	2.821LysPro: 2.821 ± 0.035	2.064LysGln: 2.064 ± 0.026	3.683LysArg: 3.683 ± 0.038	3.729LysSer: 3.729 ± 0.034	2.967LysThr: 2.967 ± 0.033	3.039LysVal: 3.039 ± 0.033	0.686LysTrp: 0.686 ± 0.013	1.34LysTyr: 1.34 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.589LeuAla: 7.589 ± 0.054	1.023LeuCys: 1.023 ± 0.017	5.096LeuAsp: 5.096 ± 0.036	5.137LeuGlu: 5.137 ± 0.04	3.098LeuPhe: 3.098 ± 0.033	5.834LeuGly: 5.834 ± 0.046	2.052LeuHis: 2.052 ± 0.019	3.629LeuIle: 3.629 ± 0.03	4.088LeuLys: 4.088 ± 0.035	7.812LeuLeu: 7.812 ± 0.055	1.684LeuMet: 1.684 ± 0.019	3.048LeuAsn: 3.048 ± 0.025	5.325LeuPro: 5.325 ± 0.042	3.624LeuGln: 3.624 ± 0.036	5.417LeuArg: 5.417 ± 0.042	7.086LeuSer: 7.086 ± 0.047	4.886LeuThr: 4.886 ± 0.041	5.19LeuVal: 5.19 ± 0.043	1.078LeuTrp: 1.078 ± 0.019	2.217LeuTyr: 2.217 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.219MetAla: 2.219 ± 0.021	0.211MetCys: 0.211 ± 0.007	1.287MetAsp: 1.287 ± 0.017	1.294MetGlu: 1.294 ± 0.018	0.709MetPhe: 0.709 ± 0.013	1.556MetGly: 1.556 ± 0.021	0.489MetHis: 0.489 ± 0.011	0.932MetIle: 0.932 ± 0.014	1.025MetLys: 1.025 ± 0.015	1.824MetLeu: 1.824 ± 0.023	0.566MetMet: 0.566 ± 0.012	0.816MetAsn: 0.816 ± 0.014	1.312MetPro: 1.312 ± 0.017	0.921MetGln: 0.921 ± 0.019	1.322MetArg: 1.322 ± 0.015	1.973MetSer: 1.973 ± 0.021	1.328MetThr: 1.328 ± 0.019	1.287MetVal: 1.287 ± 0.017	0.252MetTrp: 0.252 ± 0.007	0.538MetTyr: 0.538 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.336AsnAla: 3.336 ± 0.027	0.359AsnCys: 0.359 ± 0.008	1.994AsnAsp: 1.994 ± 0.024	2.004AsnGlu: 2.004 ± 0.024	1.37AsnPhe: 1.37 ± 0.019	3.204AsnGly: 3.204 ± 0.033	0.779AsnHis: 0.779 ± 0.015	1.885AsnIle: 1.885 ± 0.022	1.613AsnLys: 1.613 ± 0.02	3.106AsnLeu: 3.106 ± 0.031	0.813AsnMet: 0.813 ± 0.015	1.446AsnAsn: 1.446 ± 0.025	2.395AsnPro: 2.395 ± 0.024	1.358AsnGln: 1.358 ± 0.019	1.846AsnArg: 1.846 ± 0.021	2.658AsnSer: 2.658 ± 0.026	2.265AsnThr: 2.265 ± 0.022	2.326AsnVal: 2.326 ± 0.024	0.523AsnTrp: 0.523 ± 0.011	1.037AsnTyr: 1.037 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	5.556ProAla: 5.556 ± 0.053	0.436ProCys: 0.436 ± 0.011	3.161ProAsp: 3.161 ± 0.027	3.577ProGlu: 3.577 ± 0.03	1.969ProPhe: 1.969 ± 0.023	4.06ProGly: 4.06 ± 0.045	1.32ProHis: 1.32 ± 0.018	2.395ProIle: 2.395 ± 0.024	2.704ProLys: 2.704 ± 0.027	4.495ProLeu: 4.495 ± 0.033	1.047ProMet: 1.047 ± 0.015	2.22ProAsn: 2.22 ± 0.025	5.187ProPro: 5.187 ± 0.088	2.587ProGln: 2.587 ± 0.034	3.321ProArg: 3.321 ± 0.034	6.362ProSer: 6.362 ± 0.057	4.337ProThr: 4.337 ± 0.046	3.477ProVal: 3.477 ± 0.04	0.668ProTrp: 0.668 ± 0.012	1.493ProTyr: 1.493 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.679GlnAla: 3.679 ± 0.03	0.414GlnCys: 0.414 ± 0.011	2.22GlnAsp: 2.22 ± 0.021	2.388GlnGlu: 2.388 ± 0.027	1.184GlnPhe: 1.184 ± 0.017	2.789GlnGly: 2.789 ± 0.029	1.051GlnHis: 1.051 ± 0.019	1.891GlnIle: 1.891 ± 0.026	2.049GlnLys: 2.049 ± 0.025	3.305GlnLeu: 3.305 ± 0.029	0.938GlnMet: 0.938 ± 0.019	1.618GlnAsn: 1.618 ± 0.021	2.542GlnPro: 2.542 ± 0.035	2.705GlnGln: 2.705 ± 0.056	2.733GlnArg: 2.733 ± 0.028	3.388GlnSer: 3.388 ± 0.03	2.539GlnThr: 2.539 ± 0.027	2.237GlnVal: 2.237 ± 0.022	0.562GlnTrp: 0.562 ± 0.012	1.189GlnTyr: 1.189 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.809ArgAla: 4.809 ± 0.032	0.6ArgCys: 0.6 ± 0.012	3.396ArgAsp: 3.396 ± 0.035	3.985ArgGlu: 3.985 ± 0.043	2.099ArgPhe: 2.099 ± 0.023	4.043ArgGly: 4.043 ± 0.043	1.454ArgHis: 1.454 ± 0.021	2.805ArgIle: 2.805 ± 0.031	3.684ArgLys: 3.684 ± 0.035	5.201ArgLeu: 5.201 ± 0.039	1.418ArgMet: 1.418 ± 0.021	2.232ArgAsn: 2.232 ± 0.028	3.633ArgPro: 3.633 ± 0.038	2.733ArgGln: 2.733 ± 0.028	5.093ArgArg: 5.093 ± 0.05	4.857ArgSer: 4.857 ± 0.046	3.52ArgThr: 3.52 ± 0.028	3.285ArgVal: 3.285 ± 0.025	0.873ArgTrp: 0.873 ± 0.015	1.597ArgTyr: 1.597 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	7.245SerAla: 7.245 ± 0.061	0.729SerCys: 0.729 ± 0.014	4.329SerAsp: 4.329 ± 0.037	4.109SerGlu: 4.109 ± 0.032	2.935SerPhe: 2.935 ± 0.026	5.894SerGly: 5.894 ± 0.048	1.819SerHis: 1.819 ± 0.021	3.796SerIle: 3.796 ± 0.033	3.88SerLys: 3.88 ± 0.035	6.895SerLeu: 6.895 ± 0.048	1.725SerMet: 1.725 ± 0.02	3.111SerAsn: 3.111 ± 0.026	5.76SerPro: 5.76 ± 0.06	3.409SerGln: 3.409 ± 0.035	4.989SerArg: 4.989 ± 0.046	9.03SerSer: 9.03 ± 0.132	6.046SerThr: 6.046 ± 0.074	4.554SerVal: 4.554 ± 0.035	1.013SerTrp: 1.013 ± 0.015	2.042SerTyr: 2.042 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.615ThrAla: 5.615 ± 0.04	0.709ThrCys: 0.709 ± 0.015	2.954ThrAsp: 2.954 ± 0.026	3.076ThrGlu: 3.076 ± 0.029	2.312ThrPhe: 2.312 ± 0.025	4.473ThrGly: 4.473 ± 0.039	1.261ThrHis: 1.261 ± 0.016	3.088ThrIle: 3.088 ± 0.031	2.777ThrLys: 2.777 ± 0.03	5.128ThrLeu: 5.128 ± 0.038	1.191ThrMet: 1.191 ± 0.014	2.301ThrAsn: 2.301 ± 0.022	4.562ThrPro: 4.562 ± 0.048	2.226ThrGln: 2.226 ± 0.027	3.132ThrArg: 3.132 ± 0.027	5.99ThrSer: 5.99 ± 0.073	5.322ThrThr: 5.322 ± 0.116	3.772ThrVal: 3.772 ± 0.036	0.825ThrTrp: 0.825 ± 0.013	1.674ThrTyr: 1.674 ± 0.023	0.0ThrXaa: 0.0 ± 0.0
Val	5.264ValAla: 5.264 ± 0.04	0.716ValCys: 0.716 ± 0.013	3.68ValAsp: 3.68 ± 0.03	4.054ValGlu: 4.054 ± 0.034	2.33ValPhe: 2.33 ± 0.028	4.275ValGly: 4.275 ± 0.038	1.302ValHis: 1.302 ± 0.017	2.748ValIle: 2.748 ± 0.023	3.16ValLys: 3.16 ± 0.03	5.403ValLeu: 5.403 ± 0.042	1.333ValMet: 1.333 ± 0.018	2.251ValAsn: 2.251 ± 0.023	3.553ValPro: 3.553 ± 0.033	2.502ValGln: 2.502 ± 0.025	3.665ValArg: 3.665 ± 0.033	4.504ValSer: 4.504 ± 0.036	3.533ValThr: 3.533 ± 0.038	4.423ValVal: 4.423 ± 0.038	0.858ValTrp: 0.858 ± 0.014	1.627ValTyr: 1.627 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.051TrpAla: 1.051 ± 0.016	0.172TrpCys: 0.172 ± 0.006	0.848TrpAsp: 0.848 ± 0.016	0.787TrpGlu: 0.787 ± 0.014	0.52TrpPhe: 0.52 ± 0.012	0.935TrpGly: 0.935 ± 0.015	0.309TrpHis: 0.309 ± 0.009	0.726TrpIle: 0.726 ± 0.013	0.739TrpLys: 0.739 ± 0.013	1.261TrpLeu: 1.261 ± 0.021	0.366TrpMet: 0.366 ± 0.008	0.593TrpAsn: 0.593 ± 0.013	0.565TrpPro: 0.565 ± 0.012	0.577TrpGln: 0.577 ± 0.012	0.958TrpArg: 0.958 ± 0.015	1.054TrpSer: 1.054 ± 0.018	0.92TrpThr: 0.92 ± 0.014	0.814TrpVal: 0.814 ± 0.015	0.252TrpTrp: 0.252 ± 0.007	0.423TrpTyr: 0.423 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.195TyrAla: 2.195 ± 0.025	0.379TyrCys: 0.379 ± 0.009	1.679TyrAsp: 1.679 ± 0.02	1.465TyrGlu: 1.465 ± 0.017	1.156TyrPhe: 1.156 ± 0.017	2.148TyrGly: 2.148 ± 0.027	0.701TyrHis: 0.701 ± 0.014	1.289TyrIle: 1.289 ± 0.021	1.082TyrLys: 1.082 ± 0.015	2.483TyrLeu: 2.483 ± 0.028	0.603TyrMet: 0.603 ± 0.012	1.116TyrAsn: 1.116 ± 0.016	1.471TyrPro: 1.471 ± 0.021	1.136TyrGln: 1.136 ± 0.018	1.544TyrArg: 1.544 ± 0.02	1.887TyrSer: 1.887 ± 0.022	1.624TyrThr: 1.624 ± 0.023	1.588TyrVal: 1.588 ± 0.019	0.424TyrTrp: 0.424 ± 0.011	0.922TyrTyr: 0.922 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9222 proteins (4626512 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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