Amino acid dipepetide frequency for Changjiang tombus-like virus 15

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.883AlaAla: 10.883 ± 2.788
1.209AlaCys: 1.209 ± 1.074
1.209AlaAsp: 1.209 ± 0.646
2.418AlaGlu: 2.418 ± 0.428
4.837AlaPhe: 4.837 ± 0.857
10.883AlaGly: 10.883 ± 6.227
1.209AlaHis: 1.209 ± 0.646
4.837AlaIle: 4.837 ± 0.857
9.674AlaLys: 9.674 ± 1.714
8.464AlaLeu: 8.464 ± 1.08
1.209AlaMet: 1.209 ± 1.074
1.209AlaAsn: 1.209 ± 1.074
1.209AlaPro: 1.209 ± 0.646
0.0AlaGln: 0.0 ± 0.0
4.837AlaArg: 4.837 ± 0.863
3.628AlaSer: 3.628 ± 1.502
3.628AlaThr: 3.628 ± 3.222
8.464AlaVal: 8.464 ± 0.639
1.209AlaTrp: 1.209 ± 0.646
1.209AlaTyr: 1.209 ± 0.646
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
3.628CysPhe: 3.628 ± 1.937
2.418CysGly: 2.418 ± 0.428
2.418CysHis: 2.418 ± 1.291
1.209CysIle: 1.209 ± 1.074
2.418CysLys: 2.418 ± 0.428
3.628CysLeu: 3.628 ± 0.217
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.209CysGln: 1.209 ± 0.646
1.209CysArg: 1.209 ± 0.646
2.418CysSer: 2.418 ± 0.428
1.209CysThr: 1.209 ± 1.074
1.209CysVal: 1.209 ± 0.646
0.0CysTrp: 0.0 ± 0.0
1.209CysTyr: 1.209 ± 0.646
0.0CysXaa: 0.0 ± 0.0
Asp
2.418AspAla: 2.418 ± 1.291
1.209AspCys: 1.209 ± 0.646
4.837AspAsp: 4.837 ± 0.863
3.628AspGlu: 3.628 ± 1.937
0.0AspPhe: 0.0 ± 0.0
4.837AspGly: 4.837 ± 2.583
1.209AspHis: 1.209 ± 0.646
0.0AspIle: 0.0 ± 0.0
0.0AspLys: 0.0 ± 0.0
3.628AspLeu: 3.628 ± 0.217
2.418AspMet: 2.418 ± 1.291
1.209AspAsn: 1.209 ± 1.074
2.418AspPro: 2.418 ± 0.428
2.418AspGln: 2.418 ± 1.291
0.0AspArg: 0.0 ± 0.0
4.837AspSer: 4.837 ± 0.857
2.418AspThr: 2.418 ± 0.428
2.418AspVal: 2.418 ± 0.428
1.209AspTrp: 1.209 ± 0.646
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.628GluAla: 3.628 ± 1.937
2.418GluCys: 2.418 ± 0.428
0.0GluAsp: 0.0 ± 0.0
3.628GluGlu: 3.628 ± 1.937
2.418GluPhe: 2.418 ± 1.291
1.209GluGly: 1.209 ± 0.646
4.837GluHis: 4.837 ± 2.583
3.628GluIle: 3.628 ± 0.217
1.209GluLys: 1.209 ± 0.646
4.837GluLeu: 4.837 ± 0.863
0.0GluMet: 0.0 ± 0.539
1.209GluAsn: 1.209 ± 0.646
3.628GluPro: 3.628 ± 1.937
3.628GluGln: 3.628 ± 0.217
6.046GluArg: 6.046 ± 3.228
1.209GluSer: 1.209 ± 0.646
3.628GluThr: 3.628 ± 1.502
1.209GluVal: 1.209 ± 0.646
1.209GluTrp: 1.209 ± 1.074
2.418GluTyr: 2.418 ± 1.291
0.0GluXaa: 0.0 ± 0.0
Phe
1.209PheAla: 1.209 ± 1.074
1.209PheCys: 1.209 ± 0.646
3.628PheAsp: 3.628 ± 0.217
2.418PheGlu: 2.418 ± 1.291
0.0PhePhe: 0.0 ± 0.0
2.418PheGly: 2.418 ± 1.291
1.209PheHis: 1.209 ± 1.074
2.418PheIle: 2.418 ± 1.291
1.209PheLys: 1.209 ± 0.646
2.418PheLeu: 2.418 ± 0.428
2.418PheMet: 2.418 ± 1.291
4.837PheAsn: 4.837 ± 2.583
2.418PhePro: 2.418 ± 1.291
0.0PheGln: 0.0 ± 0.0
1.209PheArg: 1.209 ± 1.074
2.418PheSer: 2.418 ± 0.428
3.628PheThr: 3.628 ± 0.217
4.837PheVal: 4.837 ± 0.857
1.209PheTrp: 1.209 ± 0.646
2.418PheTyr: 2.418 ± 1.291
0.0PheXaa: 0.0 ± 0.0
Gly
7.255GlyAla: 7.255 ± 4.725
3.628GlyCys: 3.628 ± 1.937
4.837GlyAsp: 4.837 ± 0.863
7.255GlyGlu: 7.255 ± 0.435
2.418GlyPhe: 2.418 ± 1.291
6.046GlyGly: 6.046 ± 1.931
1.209GlyHis: 1.209 ± 0.646
4.837GlyIle: 4.837 ± 0.857
2.418GlyLys: 2.418 ± 0.428
16.929GlyLeu: 16.929 ± 2.161
0.0GlyMet: 0.0 ± 0.0
4.837GlyAsn: 4.837 ± 2.577
3.628GlyPro: 3.628 ± 1.502
1.209GlyGln: 1.209 ± 1.074
4.837GlyArg: 4.837 ± 0.863
3.628GlySer: 3.628 ± 3.222
3.628GlyThr: 3.628 ± 0.217
4.837GlyVal: 4.837 ± 0.857
1.209GlyTrp: 1.209 ± 1.074
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.209HisAsp: 1.209 ± 0.646
1.209HisGlu: 1.209 ± 1.074
0.0HisPhe: 0.0 ± 0.0
2.418HisGly: 2.418 ± 0.428
1.209HisHis: 1.209 ± 0.646
0.0HisIle: 0.0 ± 0.0
3.628HisLys: 3.628 ± 1.937
4.837HisLeu: 4.837 ± 0.863
0.0HisMet: 0.0 ± 0.0
2.418HisAsn: 2.418 ± 0.428
3.628HisPro: 3.628 ± 0.217
0.0HisGln: 0.0 ± 0.0
2.418HisArg: 2.418 ± 1.291
4.837HisSer: 4.837 ± 2.583
0.0HisThr: 0.0 ± 0.0
2.418HisVal: 2.418 ± 1.291
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.837IleAla: 4.837 ± 2.577
1.209IleCys: 1.209 ± 1.074
1.209IleAsp: 1.209 ± 0.646
3.628IleGlu: 3.628 ± 1.937
2.418IlePhe: 2.418 ± 0.428
1.209IleGly: 1.209 ± 1.074
1.209IleHis: 1.209 ± 0.646
0.0IleIle: 0.0 ± 0.0
6.046IleLys: 6.046 ± 1.509
3.628IleLeu: 3.628 ± 1.502
1.209IleMet: 1.209 ± 0.646
2.418IleAsn: 2.418 ± 0.428
1.209IlePro: 1.209 ± 1.074
0.0IleGln: 0.0 ± 0.0
2.418IleArg: 2.418 ± 1.291
1.209IleSer: 1.209 ± 0.646
4.837IleThr: 4.837 ± 0.857
2.418IleVal: 2.418 ± 0.428
0.0IleTrp: 0.0 ± 0.0
2.418IleTyr: 2.418 ± 0.428
0.0IleXaa: 0.0 ± 0.0
Lys
7.255LysAla: 7.255 ± 0.435
0.0LysCys: 0.0 ± 0.0
2.418LysAsp: 2.418 ± 1.291
3.628LysGlu: 3.628 ± 1.937
0.0LysPhe: 0.0 ± 0.0
4.837LysGly: 4.837 ± 0.863
3.628LysHis: 3.628 ± 0.217
0.0LysIle: 0.0 ± 0.0
2.418LysLys: 2.418 ± 0.428
3.628LysLeu: 3.628 ± 1.937
3.628LysMet: 3.628 ± 1.502
1.209LysAsn: 1.209 ± 1.074
3.628LysPro: 3.628 ± 1.937
2.418LysGln: 2.418 ± 1.291
3.628LysArg: 3.628 ± 0.217
4.837LysSer: 4.837 ± 2.577
1.209LysThr: 1.209 ± 1.074
2.418LysVal: 2.418 ± 0.428
1.209LysTrp: 1.209 ± 0.646
1.209LysTyr: 1.209 ± 0.646
0.0LysXaa: 0.0 ± 0.0
Leu
4.837LeuAla: 4.837 ± 4.296
2.418LeuCys: 2.418 ± 1.291
3.628LeuAsp: 3.628 ± 1.937
7.255LeuGlu: 7.255 ± 3.874
7.255LeuPhe: 7.255 ± 0.435
8.464LeuGly: 8.464 ± 1.08
0.0LeuHis: 0.0 ± 0.0
4.837LeuIle: 4.837 ± 2.583
0.0LeuLys: 0.0 ± 0.0
10.883LeuLeu: 10.883 ± 2.788
2.418LeuMet: 2.418 ± 0.445
6.046LeuAsn: 6.046 ± 1.931
4.837LeuPro: 4.837 ± 0.863
4.837LeuGln: 4.837 ± 0.857
7.255LeuArg: 7.255 ± 3.874
7.255LeuSer: 7.255 ± 0.435
6.046LeuThr: 6.046 ± 5.37
3.628LeuVal: 3.628 ± 1.937
1.209LeuTrp: 1.209 ± 1.074
3.628LeuTyr: 3.628 ± 0.217
0.0LeuXaa: 0.0 ± 0.0
Met
1.209MetAla: 1.209 ± 1.074
1.209MetCys: 1.209 ± 0.646
1.209MetAsp: 1.209 ± 0.646
2.418MetGlu: 2.418 ± 1.291
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.418MetLys: 2.418 ± 1.291
1.209MetLeu: 1.209 ± 0.646
1.209MetMet: 1.209 ± 0.646
1.209MetAsn: 1.209 ± 0.646
3.628MetPro: 3.628 ± 0.217
0.0MetGln: 0.0 ± 0.0
1.209MetArg: 1.209 ± 1.074
1.209MetSer: 1.209 ± 0.646
1.209MetThr: 1.209 ± 0.646
3.628MetVal: 3.628 ± 1.502
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.418AsnAla: 2.418 ± 2.148
2.418AsnCys: 2.418 ± 0.428
4.837AsnAsp: 4.837 ± 0.857
0.0AsnGlu: 0.0 ± 0.0
4.837AsnPhe: 4.837 ± 0.863
2.418AsnGly: 2.418 ± 0.428
1.209AsnHis: 1.209 ± 0.646
4.837AsnIle: 4.837 ± 0.857
1.209AsnLys: 1.209 ± 1.074
1.209AsnLeu: 1.209 ± 1.074
1.209AsnMet: 1.209 ± 0.646
2.418AsnAsn: 2.418 ± 0.428
2.418AsnPro: 2.418 ± 2.148
1.209AsnGln: 1.209 ± 0.646
0.0AsnArg: 0.0 ± 0.0
4.837AsnSer: 4.837 ± 0.863
3.628AsnThr: 3.628 ± 1.502
2.418AsnVal: 2.418 ± 2.148
0.0AsnTrp: 0.0 ± 0.0
2.418AsnTyr: 2.418 ± 0.428
0.0AsnXaa: 0.0 ± 0.0
Pro
8.464ProAla: 8.464 ± 0.639
1.209ProCys: 1.209 ± 1.074
0.0ProAsp: 0.0 ± 0.0
2.418ProGlu: 2.418 ± 1.291
0.0ProPhe: 0.0 ± 0.0
3.628ProGly: 3.628 ± 1.502
1.209ProHis: 1.209 ± 0.646
3.628ProIle: 3.628 ± 0.217
4.837ProLys: 4.837 ± 0.863
2.418ProLeu: 2.418 ± 1.291
1.209ProMet: 1.209 ± 1.074
3.628ProAsn: 3.628 ± 0.217
3.628ProPro: 3.628 ± 1.937
1.209ProGln: 1.209 ± 1.074
4.837ProArg: 4.837 ± 2.583
3.628ProSer: 3.628 ± 0.217
4.837ProThr: 4.837 ± 0.863
2.418ProVal: 2.418 ± 1.291
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.209GlnAla: 1.209 ± 1.074
1.209GlnCys: 1.209 ± 0.646
0.0GlnAsp: 0.0 ± 0.0
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
2.418GlnGly: 2.418 ± 0.428
1.209GlnHis: 1.209 ± 0.646
1.209GlnIle: 1.209 ± 0.646
2.418GlnLys: 2.418 ± 0.428
3.628GlnLeu: 3.628 ± 1.502
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.209GlnPro: 1.209 ± 0.646
0.0GlnGln: 0.0 ± 0.0
3.628GlnArg: 3.628 ± 0.217
2.418GlnSer: 2.418 ± 0.428
0.0GlnThr: 0.0 ± 0.0
4.837GlnVal: 4.837 ± 2.577
2.418GlnTrp: 2.418 ± 1.291
1.209GlnTyr: 1.209 ± 0.646
0.0GlnXaa: 0.0 ± 0.0
Arg
3.628ArgAla: 3.628 ± 1.937
0.0ArgCys: 0.0 ± 0.0
1.209ArgAsp: 1.209 ± 0.646
2.418ArgGlu: 2.418 ± 1.291
2.418ArgPhe: 2.418 ± 0.428
8.464ArgGly: 8.464 ± 1.08
2.418ArgHis: 2.418 ± 1.291
2.418ArgIle: 2.418 ± 0.428
4.837ArgLys: 4.837 ± 0.857
7.255ArgLeu: 7.255 ± 0.435
1.209ArgMet: 1.209 ± 0.646
2.418ArgAsn: 2.418 ± 1.291
2.418ArgPro: 2.418 ± 0.428
2.418ArgGln: 2.418 ± 0.428
2.418ArgArg: 2.418 ± 1.291
2.418ArgSer: 2.418 ± 0.428
3.628ArgThr: 3.628 ± 1.937
1.209ArgVal: 1.209 ± 0.646
0.0ArgTrp: 0.0 ± 0.0
3.628ArgTyr: 3.628 ± 0.217
0.0ArgXaa: 0.0 ± 0.0
Ser
4.837SerAla: 4.837 ± 2.577
0.0SerCys: 0.0 ± 0.0
4.837SerAsp: 4.837 ± 0.857
1.209SerGlu: 1.209 ± 0.646
2.418SerPhe: 2.418 ± 1.291
6.046SerGly: 6.046 ± 0.211
2.418SerHis: 2.418 ± 2.148
6.046SerIle: 6.046 ± 1.931
4.837SerLys: 4.837 ± 0.863
7.255SerLeu: 7.255 ± 0.435
0.0SerMet: 0.0 ± 0.0
3.628SerAsn: 3.628 ± 3.222
7.255SerPro: 7.255 ± 2.154
2.418SerGln: 2.418 ± 0.428
4.837SerArg: 4.837 ± 0.857
3.628SerSer: 3.628 ± 1.502
3.628SerThr: 3.628 ± 1.502
6.046SerVal: 6.046 ± 1.931
1.209SerTrp: 1.209 ± 0.646
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.837ThrAla: 4.837 ± 0.857
1.209ThrCys: 1.209 ± 1.074
3.628ThrAsp: 3.628 ± 0.217
0.0ThrGlu: 0.0 ± 0.0
3.628ThrPhe: 3.628 ± 0.217
7.255ThrGly: 7.255 ± 3.005
2.418ThrHis: 2.418 ± 1.291
1.209ThrIle: 1.209 ± 0.646
1.209ThrLys: 1.209 ± 0.646
3.628ThrLeu: 3.628 ± 3.222
1.209ThrMet: 1.209 ± 0.646
1.209ThrAsn: 1.209 ± 1.074
2.418ThrPro: 2.418 ± 0.428
1.209ThrGln: 1.209 ± 1.074
2.418ThrArg: 2.418 ± 0.428
7.255ThrSer: 7.255 ± 4.725
8.464ThrThr: 8.464 ± 4.079
4.837ThrVal: 4.837 ± 0.857
0.0ThrTrp: 0.0 ± 0.0
2.418ThrTyr: 2.418 ± 1.291
0.0ThrXaa: 0.0 ± 0.0
Val
8.464ValAla: 8.464 ± 1.08
2.418ValCys: 2.418 ± 1.291
1.209ValAsp: 1.209 ± 0.646
4.837ValGlu: 4.837 ± 0.857
6.046ValPhe: 6.046 ± 1.509
7.255ValGly: 7.255 ± 1.285
0.0ValHis: 0.0 ± 0.0
2.418ValIle: 2.418 ± 2.148
1.209ValLys: 1.209 ± 0.646
3.628ValLeu: 3.628 ± 0.217
2.418ValMet: 2.418 ± 1.291
2.418ValAsn: 2.418 ± 2.148
3.628ValPro: 3.628 ± 0.217
2.418ValGln: 2.418 ± 2.148
2.418ValArg: 2.418 ± 2.148
6.046ValSer: 6.046 ± 1.931
1.209ValThr: 1.209 ± 0.646
4.837ValVal: 4.837 ± 2.577
2.418ValTrp: 2.418 ± 1.291
1.209ValTyr: 1.209 ± 1.074
0.0ValXaa: 0.0 ± 0.0
Trp
1.209TrpAla: 1.209 ± 0.646
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.209TrpGlu: 1.209 ± 0.646
1.209TrpPhe: 1.209 ± 0.646
1.209TrpGly: 1.209 ± 0.646
1.209TrpHis: 1.209 ± 1.074
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
3.628TrpAsn: 3.628 ± 0.217
0.0TrpPro: 0.0 ± 0.0
1.209TrpGln: 1.209 ± 0.646
0.0TrpArg: 0.0 ± 0.0
1.209TrpSer: 1.209 ± 0.646
2.418TrpThr: 2.418 ± 0.428
0.0TrpVal: 0.0 ± 0.0
1.209TrpTrp: 1.209 ± 1.074
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.628TyrAla: 3.628 ± 0.217
1.209TyrCys: 1.209 ± 0.646
1.209TyrAsp: 1.209 ± 0.646
3.628TyrGlu: 3.628 ± 0.217
0.0TyrPhe: 0.0 ± 0.0
1.209TyrGly: 1.209 ± 1.074
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
1.209TyrLys: 1.209 ± 0.646
3.628TyrLeu: 3.628 ± 1.937
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
0.0TyrPro: 0.0 ± 0.0
1.209TyrGln: 1.209 ± 0.646
1.209TyrArg: 1.209 ± 1.074
3.628TyrSer: 3.628 ± 0.217
1.209TyrThr: 1.209 ± 0.646
2.418TyrVal: 2.418 ± 1.291
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (828 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski