Amino acid dipepetide frequency for Hubei tombus-like virus 36

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.415AlaAla: 5.415 ± 3.553
2.708AlaCys: 2.708 ± 0.966
4.513AlaAsp: 4.513 ± 0.218
1.805AlaGlu: 1.805 ± 1.558
2.708AlaPhe: 2.708 ± 0.405
0.903AlaGly: 0.903 ± 0.592
2.708AlaHis: 2.708 ± 0.966
5.415AlaIle: 5.415 ± 0.561
7.22AlaLys: 7.22 ± 1.995
4.513AlaLeu: 4.513 ± 1.153
0.903AlaMet: 0.903 ± 0.592
2.708AlaAsn: 2.708 ± 0.405
5.415AlaPro: 5.415 ± 2.182
0.903AlaGln: 0.903 ± 0.592
10.83AlaArg: 10.83 ± 2.992
0.903AlaSer: 0.903 ± 0.779
4.513AlaThr: 4.513 ± 1.153
2.708AlaVal: 2.708 ± 1.776
0.903AlaTrp: 0.903 ± 0.592
9.025AlaTyr: 9.025 ± 1.808
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.708CysAsp: 2.708 ± 0.405
0.903CysGlu: 0.903 ± 0.779
0.903CysPhe: 0.903 ± 0.592
1.805CysGly: 1.805 ± 1.558
0.903CysHis: 0.903 ± 0.592
0.903CysIle: 0.903 ± 0.592
0.0CysLys: 0.0 ± 0.0
1.805CysLeu: 1.805 ± 1.184
0.0CysMet: 0.0 ± 0.491
0.903CysAsn: 0.903 ± 0.592
0.903CysPro: 0.903 ± 0.779
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.903CysSer: 0.903 ± 0.592
1.805CysThr: 1.805 ± 1.558
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.903CysTyr: 0.903 ± 0.779
0.0CysXaa: 0.0 ± 0.0
Asp
6.318AspAla: 6.318 ± 0.032
0.0AspCys: 0.0 ± 0.0
1.805AspAsp: 1.805 ± 0.187
4.513AspGlu: 4.513 ± 2.524
1.805AspPhe: 1.805 ± 0.187
1.805AspGly: 1.805 ± 1.558
1.805AspHis: 1.805 ± 1.184
0.903AspIle: 0.903 ± 0.592
6.318AspLys: 6.318 ± 0.032
1.805AspLeu: 1.805 ± 1.184
2.708AspMet: 2.708 ± 0.966
3.61AspAsn: 3.61 ± 0.374
2.708AspPro: 2.708 ± 1.776
1.805AspGln: 1.805 ± 0.187
4.513AspArg: 4.513 ± 1.153
2.708AspSer: 2.708 ± 0.966
6.318AspThr: 6.318 ± 0.032
3.61AspVal: 3.61 ± 2.368
0.903AspTrp: 0.903 ± 0.592
2.708AspTyr: 2.708 ± 0.966
0.0AspXaa: 0.0 ± 0.0
Glu
5.415GluAla: 5.415 ± 1.932
2.708GluCys: 2.708 ± 0.966
4.513GluAsp: 4.513 ± 0.218
9.025GluGlu: 9.025 ± 1.808
2.708GluPhe: 2.708 ± 0.966
4.513GluGly: 4.513 ± 0.218
2.708GluHis: 2.708 ± 0.405
0.903GluIle: 0.903 ± 0.779
5.415GluLys: 5.415 ± 0.811
10.83GluLeu: 10.83 ± 2.492
1.805GluMet: 1.805 ± 1.558
1.805GluAsn: 1.805 ± 0.187
4.513GluPro: 4.513 ± 2.961
0.903GluGln: 0.903 ± 0.779
2.708GluArg: 2.708 ± 2.337
3.61GluSer: 3.61 ± 0.997
1.805GluThr: 1.805 ± 1.184
0.0GluVal: 0.0 ± 0.0
1.805GluTrp: 1.805 ± 0.187
1.805GluTyr: 1.805 ± 0.187
0.0GluXaa: 0.0 ± 0.0
Phe
2.708PheAla: 2.708 ± 0.405
0.903PheCys: 0.903 ± 0.779
2.708PheAsp: 2.708 ± 0.405
2.708PheGlu: 2.708 ± 0.966
5.415PhePhe: 5.415 ± 0.811
1.805PheGly: 1.805 ± 1.558
0.0PheHis: 0.0 ± 0.0
3.61PheIle: 3.61 ± 0.374
4.513PheLys: 4.513 ± 3.895
6.318PheLeu: 6.318 ± 1.403
2.708PheMet: 2.708 ± 2.337
1.805PheAsn: 1.805 ± 1.184
0.0PhePro: 0.0 ± 0.0
1.805PheGln: 1.805 ± 1.184
2.708PheArg: 2.708 ± 0.966
0.903PheSer: 0.903 ± 0.779
2.708PheThr: 2.708 ± 0.966
2.708PheVal: 2.708 ± 0.966
0.903PheTrp: 0.903 ± 0.592
2.708PheTyr: 2.708 ± 0.405
0.0PheXaa: 0.0 ± 0.0
Gly
3.61GlyAla: 3.61 ± 2.368
1.805GlyCys: 1.805 ± 1.558
2.708GlyAsp: 2.708 ± 0.405
2.708GlyGlu: 2.708 ± 0.966
2.708GlyPhe: 2.708 ± 0.966
6.318GlyGly: 6.318 ± 2.774
0.0GlyHis: 0.0 ± 0.0
3.61GlyIle: 3.61 ± 0.374
4.513GlyLys: 4.513 ± 0.218
4.513GlyLeu: 4.513 ± 0.218
0.0GlyMet: 0.0 ± 0.0
3.61GlyAsn: 3.61 ± 0.374
3.61GlyPro: 3.61 ± 0.374
2.708GlyGln: 2.708 ± 0.405
4.513GlyArg: 4.513 ± 0.218
2.708GlySer: 2.708 ± 0.405
0.903GlyThr: 0.903 ± 0.592
2.708GlyVal: 2.708 ± 0.966
0.903GlyTrp: 0.903 ± 0.779
0.903GlyTyr: 0.903 ± 0.779
0.0GlyXaa: 0.0 ± 0.0
His
0.903HisAla: 0.903 ± 0.779
0.0HisCys: 0.0 ± 0.0
0.903HisAsp: 0.903 ± 0.592
3.61HisGlu: 3.61 ± 0.374
1.805HisPhe: 1.805 ± 0.187
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.903HisIle: 0.903 ± 0.592
2.708HisLys: 2.708 ± 0.966
4.513HisLeu: 4.513 ± 2.524
0.903HisMet: 0.903 ± 0.592
0.903HisAsn: 0.903 ± 0.592
0.903HisPro: 0.903 ± 0.592
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
5.415HisSer: 5.415 ± 2.182
0.903HisThr: 0.903 ± 0.592
0.0HisVal: 0.0 ± 0.0
2.708HisTrp: 2.708 ± 0.966
0.903HisTyr: 0.903 ± 0.779
0.0HisXaa: 0.0 ± 0.0
Ile
2.708IleAla: 2.708 ± 0.405
2.708IleCys: 2.708 ± 1.776
3.61IleAsp: 3.61 ± 0.374
2.708IleGlu: 2.708 ± 2.337
0.903IlePhe: 0.903 ± 0.779
2.708IleGly: 2.708 ± 0.966
0.903IleHis: 0.903 ± 0.779
2.708IleIle: 2.708 ± 0.405
4.513IleLys: 4.513 ± 0.218
2.708IleLeu: 2.708 ± 1.776
1.805IleMet: 1.805 ± 0.187
3.61IleAsn: 3.61 ± 0.997
1.805IlePro: 1.805 ± 0.187
0.903IleGln: 0.903 ± 0.779
0.903IleArg: 0.903 ± 0.592
3.61IleSer: 3.61 ± 2.368
2.708IleThr: 2.708 ± 0.966
0.903IleVal: 0.903 ± 0.779
0.903IleTrp: 0.903 ± 0.592
0.903IleTyr: 0.903 ± 0.592
0.0IleXaa: 0.0 ± 0.0
Lys
6.318LysAla: 6.318 ± 0.032
0.0LysCys: 0.0 ± 0.0
4.513LysAsp: 4.513 ± 1.153
4.513LysGlu: 4.513 ± 1.153
3.61LysPhe: 3.61 ± 1.745
5.415LysGly: 5.415 ± 2.182
4.513LysHis: 4.513 ± 2.524
4.513LysIle: 4.513 ± 1.153
5.415LysLys: 5.415 ± 0.811
8.123LysLeu: 8.123 ± 0.155
0.0LysMet: 0.0 ± 0.0
3.61LysAsn: 3.61 ± 0.997
3.61LysPro: 3.61 ± 0.374
4.513LysGln: 4.513 ± 2.961
5.415LysArg: 5.415 ± 0.811
3.61LysSer: 3.61 ± 0.997
4.513LysThr: 4.513 ± 0.218
1.805LysVal: 1.805 ± 1.184
1.805LysTrp: 1.805 ± 0.187
3.61LysTyr: 3.61 ± 0.374
0.0LysXaa: 0.0 ± 0.0
Leu
6.318LeuAla: 6.318 ± 1.34
1.805LeuCys: 1.805 ± 1.184
6.318LeuAsp: 6.318 ± 2.711
3.61LeuGlu: 3.61 ± 1.745
8.123LeuPhe: 8.123 ± 4.269
4.513LeuGly: 4.513 ± 0.218
1.805LeuHis: 1.805 ± 1.184
3.61LeuIle: 3.61 ± 0.997
4.513LeuLys: 4.513 ± 1.153
5.415LeuLeu: 5.415 ± 0.561
1.805LeuMet: 1.805 ± 0.187
0.903LeuAsn: 0.903 ± 0.592
2.708LeuPro: 2.708 ± 0.966
2.708LeuGln: 2.708 ± 0.405
4.513LeuArg: 4.513 ± 1.153
9.025LeuSer: 9.025 ± 0.934
8.123LeuThr: 8.123 ± 1.216
5.415LeuVal: 5.415 ± 0.561
2.708LeuTrp: 2.708 ± 1.776
6.318LeuTyr: 6.318 ± 1.403
0.0LeuXaa: 0.0 ± 0.0
Met
0.903MetAla: 0.903 ± 0.779
0.0MetCys: 0.0 ± 0.0
1.805MetAsp: 1.805 ± 1.558
3.61MetGlu: 3.61 ± 0.997
0.0MetPhe: 0.0 ± 0.0
0.903MetGly: 0.903 ± 0.592
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.805MetLys: 1.805 ± 0.187
0.903MetLeu: 0.903 ± 0.779
0.903MetMet: 0.903 ± 0.421
1.805MetAsn: 1.805 ± 0.187
1.805MetPro: 1.805 ± 0.187
0.0MetGln: 0.0 ± 0.0
1.805MetArg: 1.805 ± 0.187
1.805MetSer: 1.805 ± 1.558
2.708MetThr: 2.708 ± 0.405
0.903MetVal: 0.903 ± 0.592
1.805MetTrp: 1.805 ± 1.558
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.61AsnAla: 3.61 ± 2.368
0.0AsnCys: 0.0 ± 0.0
3.61AsnAsp: 3.61 ± 0.374
0.903AsnGlu: 0.903 ± 0.592
0.903AsnPhe: 0.903 ± 0.779
3.61AsnGly: 3.61 ± 1.745
1.805AsnHis: 1.805 ± 0.187
1.805AsnIle: 1.805 ± 1.184
1.805AsnLys: 1.805 ± 1.184
5.415AsnLeu: 5.415 ± 0.561
1.805AsnMet: 1.805 ± 0.187
0.903AsnAsn: 0.903 ± 0.779
0.903AsnPro: 0.903 ± 0.779
0.0AsnGln: 0.0 ± 0.0
0.903AsnArg: 0.903 ± 0.779
3.61AsnSer: 3.61 ± 0.997
2.708AsnThr: 2.708 ± 0.405
4.513AsnVal: 4.513 ± 1.153
0.903AsnTrp: 0.903 ± 0.592
4.513AsnTyr: 4.513 ± 3.895
0.0AsnXaa: 0.0 ± 0.0
Pro
1.805ProAla: 1.805 ± 0.187
0.0ProCys: 0.0 ± 0.0
1.805ProAsp: 1.805 ± 0.187
6.318ProGlu: 6.318 ± 2.774
0.903ProPhe: 0.903 ± 0.592
4.513ProGly: 4.513 ± 1.153
0.903ProHis: 0.903 ± 0.592
0.0ProIle: 0.0 ± 0.0
5.415ProLys: 5.415 ± 2.182
2.708ProLeu: 2.708 ± 0.966
0.0ProMet: 0.0 ± 0.0
3.61ProAsn: 3.61 ± 1.745
1.805ProPro: 1.805 ± 1.184
0.0ProGln: 0.0 ± 0.0
3.61ProArg: 3.61 ± 2.368
0.903ProSer: 0.903 ± 0.592
2.708ProThr: 2.708 ± 0.966
4.513ProVal: 4.513 ± 2.524
1.805ProTrp: 1.805 ± 1.558
0.903ProTyr: 0.903 ± 0.592
0.0ProXaa: 0.0 ± 0.0
Gln
0.903GlnAla: 0.903 ± 0.592
0.0GlnCys: 0.0 ± 0.0
3.61GlnAsp: 3.61 ± 2.368
1.805GlnGlu: 1.805 ± 0.187
1.805GlnPhe: 1.805 ± 0.187
3.61GlnGly: 3.61 ± 2.368
0.903GlnHis: 0.903 ± 0.779
1.805GlnIle: 1.805 ± 1.184
0.0GlnLys: 0.0 ± 0.0
2.708GlnLeu: 2.708 ± 0.405
0.0GlnMet: 0.0 ± 0.0
0.903GlnAsn: 0.903 ± 0.779
1.805GlnPro: 1.805 ± 1.184
2.708GlnGln: 2.708 ± 0.405
1.805GlnArg: 1.805 ± 1.184
2.708GlnSer: 2.708 ± 1.776
1.805GlnThr: 1.805 ± 0.187
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
2.708GlnTyr: 2.708 ± 0.966
0.0GlnXaa: 0.0 ± 0.0
Arg
9.025ArgAla: 9.025 ± 0.437
2.708ArgCys: 2.708 ± 0.405
1.805ArgAsp: 1.805 ± 1.184
2.708ArgGlu: 2.708 ± 0.405
1.805ArgPhe: 1.805 ± 1.558
0.903ArgGly: 0.903 ± 0.592
3.61ArgHis: 3.61 ± 0.374
0.903ArgIle: 0.903 ± 0.592
6.318ArgLys: 6.318 ± 2.774
4.513ArgLeu: 4.513 ± 2.524
3.61ArgMet: 3.61 ± 0.997
4.513ArgAsn: 4.513 ± 1.153
4.513ArgPro: 4.513 ± 1.153
3.61ArgGln: 3.61 ± 2.368
1.805ArgArg: 1.805 ± 0.187
6.318ArgSer: 6.318 ± 0.032
1.805ArgThr: 1.805 ± 1.558
1.805ArgVal: 1.805 ± 0.187
0.0ArgTrp: 0.0 ± 0.0
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
8.123SerAla: 8.123 ± 5.329
0.0SerCys: 0.0 ± 0.0
2.708SerAsp: 2.708 ± 0.405
2.708SerGlu: 2.708 ± 1.776
2.708SerPhe: 2.708 ± 0.966
3.61SerGly: 3.61 ± 0.374
0.903SerHis: 0.903 ± 0.779
5.415SerIle: 5.415 ± 0.811
4.513SerLys: 4.513 ± 0.218
7.22SerLeu: 7.22 ± 0.747
0.903SerMet: 0.903 ± 0.592
1.805SerAsn: 1.805 ± 0.187
0.0SerPro: 0.0 ± 0.0
0.903SerGln: 0.903 ± 0.779
2.708SerArg: 2.708 ± 0.966
3.61SerSer: 3.61 ± 0.997
0.903SerThr: 0.903 ± 0.592
3.61SerVal: 3.61 ± 0.997
0.903SerTrp: 0.903 ± 0.779
2.708SerTyr: 2.708 ± 1.776
0.0SerXaa: 0.0 ± 0.0
Thr
7.22ThrAla: 7.22 ± 1.995
0.0ThrCys: 0.0 ± 0.0
4.513ThrAsp: 4.513 ± 2.524
2.708ThrGlu: 2.708 ± 0.966
4.513ThrPhe: 4.513 ± 0.218
2.708ThrGly: 2.708 ± 0.966
0.0ThrHis: 0.0 ± 0.0
2.708ThrIle: 2.708 ± 0.966
5.415ThrLys: 5.415 ± 0.811
3.61ThrLeu: 3.61 ± 0.997
0.0ThrMet: 0.0 ± 0.0
4.513ThrAsn: 4.513 ± 2.524
2.708ThrPro: 2.708 ± 2.337
3.61ThrGln: 3.61 ± 0.997
6.318ThrArg: 6.318 ± 1.403
1.805ThrSer: 1.805 ± 0.187
4.513ThrThr: 4.513 ± 0.218
3.61ThrVal: 3.61 ± 0.374
0.903ThrTrp: 0.903 ± 0.592
0.903ThrTyr: 0.903 ± 0.592
0.0ThrXaa: 0.0 ± 0.0
Val
0.903ValAla: 0.903 ± 0.592
0.903ValCys: 0.903 ± 0.779
1.805ValAsp: 1.805 ± 0.187
9.025ValGlu: 9.025 ± 0.437
2.708ValPhe: 2.708 ± 1.776
3.61ValGly: 3.61 ± 0.374
0.903ValHis: 0.903 ± 0.592
0.903ValIle: 0.903 ± 0.779
4.513ValLys: 4.513 ± 0.218
2.708ValLeu: 2.708 ± 0.966
0.903ValMet: 0.903 ± 0.779
0.903ValAsn: 0.903 ± 0.779
1.805ValPro: 1.805 ± 1.184
1.805ValGln: 1.805 ± 1.184
2.708ValArg: 2.708 ± 0.966
1.805ValSer: 1.805 ± 1.184
2.708ValThr: 2.708 ± 0.966
0.903ValVal: 0.903 ± 0.779
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.903TrpAla: 0.903 ± 0.592
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.805TrpGlu: 1.805 ± 0.187
0.903TrpPhe: 0.903 ± 0.779
0.903TrpGly: 0.903 ± 0.592
0.0TrpHis: 0.0 ± 0.0
0.903TrpIle: 0.903 ± 0.592
0.903TrpLys: 0.903 ± 0.779
5.415TrpLeu: 5.415 ± 0.561
0.0TrpMet: 0.0 ± 0.0
0.903TrpAsn: 0.903 ± 0.779
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.903TrpArg: 0.903 ± 0.592
0.0TrpSer: 0.0 ± 0.0
3.61TrpThr: 3.61 ± 0.374
0.903TrpVal: 0.903 ± 0.592
0.903TrpTrp: 0.903 ± 0.592
2.708TrpTyr: 2.708 ± 0.405
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.61TyrAla: 3.61 ± 3.116
0.0TyrCys: 0.0 ± 0.0
2.708TyrAsp: 2.708 ± 1.776
1.805TyrGlu: 1.805 ± 1.184
2.708TyrPhe: 2.708 ± 1.776
0.903TyrGly: 0.903 ± 0.592
3.61TyrHis: 3.61 ± 0.997
2.708TyrIle: 2.708 ± 0.966
3.61TyrLys: 3.61 ± 3.116
4.513TyrLeu: 4.513 ± 0.218
1.805TyrMet: 1.805 ± 0.187
0.903TyrAsn: 0.903 ± 0.592
2.708TyrPro: 2.708 ± 2.337
2.708TyrGln: 2.708 ± 0.405
3.61TyrArg: 3.61 ± 0.374
0.0TyrSer: 0.0 ± 0.0
4.513TyrThr: 4.513 ± 0.218
0.903TyrVal: 0.903 ± 0.592
0.903TyrTrp: 0.903 ± 0.592
1.805TyrTyr: 1.805 ± 0.187
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1109 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski