Amino acid dipepetide frequency for Alteripontixanthobacter maritimus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.378AlaAla: 17.378 ± 0.25	0.994AlaCys: 0.994 ± 0.038	7.943AlaAsp: 7.943 ± 0.115	7.894AlaGlu: 7.894 ± 0.12	4.118AlaPhe: 4.118 ± 0.077	10.766AlaGly: 10.766 ± 0.131	2.092AlaHis: 2.092 ± 0.059	6.82AlaIle: 6.82 ± 0.1	4.639AlaLys: 4.639 ± 0.09	12.908AlaLeu: 12.908 ± 0.174	4.093AlaMet: 4.093 ± 0.081	3.509AlaAsn: 3.509 ± 0.07	5.817AlaPro: 5.817 ± 0.099	4.693AlaGln: 4.693 ± 0.09	8.775AlaArg: 8.775 ± 0.137	6.63AlaSer: 6.63 ± 0.104	6.157AlaThr: 6.157 ± 0.094	8.092AlaVal: 8.092 ± 0.115	1.378AlaTrp: 1.378 ± 0.051	2.451AlaTyr: 2.451 ± 0.068	0.0AlaXaa: 0.0 ± 0.0
Cys	1.022CysAla: 1.022 ± 0.035	0.077CysCys: 0.077 ± 0.01	0.589CysAsp: 0.589 ± 0.028	0.527CysGlu: 0.527 ± 0.026	0.279CysPhe: 0.279 ± 0.018	0.839CysGly: 0.839 ± 0.03	0.197CysHis: 0.197 ± 0.018	0.391CysIle: 0.391 ± 0.024	0.197CysLys: 0.197 ± 0.017	0.642CysLeu: 0.642 ± 0.026	0.142CysMet: 0.142 ± 0.013	0.222CysAsn: 0.222 ± 0.017	0.39CysPro: 0.39 ± 0.024	0.199CysGln: 0.199 ± 0.017	0.5CysArg: 0.5 ± 0.025	0.469CysSer: 0.469 ± 0.025	0.371CysThr: 0.371 ± 0.021	0.524CysVal: 0.524 ± 0.026	0.097CysTrp: 0.097 ± 0.011	0.166CysTyr: 0.166 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	8.215AspAla: 8.215 ± 0.109	0.501AspCys: 0.501 ± 0.026	4.119AspAsp: 4.119 ± 0.094	4.019AspGlu: 4.019 ± 0.077	2.286AspPhe: 2.286 ± 0.06	6.275AspGly: 6.275 ± 0.094	1.267AspHis: 1.267 ± 0.04	3.339AspIle: 3.339 ± 0.073	1.983AspLys: 1.983 ± 0.061	5.816AspLeu: 5.816 ± 0.083	1.723AspMet: 1.723 ± 0.046	1.747AspAsn: 1.747 ± 0.051	3.59AspPro: 3.59 ± 0.076	1.688AspGln: 1.688 ± 0.052	5.013AspArg: 5.013 ± 0.084	2.622AspSer: 2.622 ± 0.058	3.604AspThr: 3.604 ± 0.081	4.178AspVal: 4.178 ± 0.073	1.111AspTrp: 1.111 ± 0.034	1.668AspTyr: 1.668 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	7.822GluAla: 7.822 ± 0.103	0.447GluCys: 0.447 ± 0.021	3.389GluAsp: 3.389 ± 0.067	3.513GluGlu: 3.513 ± 0.075	1.827GluPhe: 1.827 ± 0.05	4.706GluGly: 4.706 ± 0.087	1.205GluHis: 1.205 ± 0.039	3.006GluIle: 3.006 ± 0.068	2.198GluLys: 2.198 ± 0.057	5.785GluLeu: 5.785 ± 0.098	1.683GluMet: 1.683 ± 0.043	1.752GluAsn: 1.752 ± 0.048	2.819GluPro: 2.819 ± 0.072	2.356GluGln: 2.356 ± 0.051	4.92GluArg: 4.92 ± 0.089	2.448GluSer: 2.448 ± 0.053	3.614GluThr: 3.614 ± 0.08	3.717GluVal: 3.717 ± 0.084	0.872GluTrp: 0.872 ± 0.03	1.183GluTyr: 1.183 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	4.99PheAla: 4.99 ± 0.087	0.336PheCys: 0.336 ± 0.021	2.788PheAsp: 2.788 ± 0.063	2.154PheGlu: 2.154 ± 0.051	1.307PhePhe: 1.307 ± 0.045	3.745PheGly: 3.745 ± 0.08	0.617PheHis: 0.617 ± 0.028	1.53PheIle: 1.53 ± 0.043	0.949PheLys: 0.949 ± 0.034	2.998PheLeu: 2.998 ± 0.067	0.756PheMet: 0.756 ± 0.03	0.96PheAsn: 0.96 ± 0.039	1.43PhePro: 1.43 ± 0.046	0.916PheGln: 0.916 ± 0.034	2.03PheArg: 2.03 ± 0.05	1.981PheSer: 1.981 ± 0.054	2.139PheThr: 2.139 ± 0.045	2.573PheVal: 2.573 ± 0.057	0.496PheTrp: 0.496 ± 0.026	0.914PheTyr: 0.914 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	9.593GlyAla: 9.593 ± 0.126	0.802GlyCys: 0.802 ± 0.036	5.262GlyAsp: 5.262 ± 0.079	5.462GlyGlu: 5.462 ± 0.079	3.62GlyPhe: 3.62 ± 0.078	8.215GlyGly: 8.215 ± 0.15	1.727GlyHis: 1.727 ± 0.053	4.398GlyIle: 4.398 ± 0.08	3.638GlyLys: 3.638 ± 0.086	8.255GlyLeu: 8.255 ± 0.117	2.477GlyMet: 2.477 ± 0.061	2.568GlyAsn: 2.568 ± 0.075	3.583GlyPro: 3.583 ± 0.067	2.976GlyGln: 2.976 ± 0.072	6.025GlyArg: 6.025 ± 0.093	5.156GlySer: 5.156 ± 0.092	5.039GlyThr: 5.039 ± 0.08	5.911GlyVal: 5.911 ± 0.107	1.53GlyTrp: 1.53 ± 0.047	2.173GlyTyr: 2.173 ± 0.058	0.0GlyXaa: 0.0 ± 0.0
His	2.102HisAla: 2.102 ± 0.06	0.237HisCys: 0.237 ± 0.017	1.248HisAsp: 1.248 ± 0.042	1.031HisGlu: 1.031 ± 0.034	0.745HisPhe: 0.745 ± 0.033	1.857HisGly: 1.857 ± 0.046	0.517HisHis: 0.517 ± 0.028	0.915HisIle: 0.915 ± 0.035	0.474HisLys: 0.474 ± 0.026	1.676HisLeu: 1.676 ± 0.047	0.454HisMet: 0.454 ± 0.024	0.494HisAsn: 0.494 ± 0.029	1.218HisPro: 1.218 ± 0.041	0.496HisGln: 0.496 ± 0.027	1.39HisArg: 1.39 ± 0.045	1.015HisSer: 1.015 ± 0.038	0.865HisThr: 0.865 ± 0.037	1.16HisVal: 1.16 ± 0.043	0.319HisTrp: 0.319 ± 0.019	0.516HisTyr: 0.516 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	7.616IleAla: 7.616 ± 0.126	0.465IleCys: 0.465 ± 0.025	3.818IleAsp: 3.818 ± 0.064	3.608IleGlu: 3.608 ± 0.078	1.558IlePhe: 1.558 ± 0.049	5.207IleGly: 5.207 ± 0.094	0.849IleHis: 0.849 ± 0.038	2.197IleIle: 2.197 ± 0.058	1.27IleLys: 1.27 ± 0.047	3.837IleLeu: 3.837 ± 0.076	1.05IleMet: 1.05 ± 0.036	1.246IleAsn: 1.246 ± 0.045	2.303IlePro: 2.303 ± 0.054	1.088IleGln: 1.088 ± 0.038	3.049IleArg: 3.049 ± 0.062	2.514IleSer: 2.514 ± 0.06	2.704IleThr: 2.704 ± 0.062	4.05IleVal: 4.05 ± 0.08	0.627IleTrp: 0.627 ± 0.028	1.028IleTyr: 1.028 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	4.1LysAla: 4.1 ± 0.092	0.184LysCys: 0.184 ± 0.015	1.866LysAsp: 1.866 ± 0.057	1.452LysGlu: 1.452 ± 0.041	0.99LysPhe: 0.99 ± 0.036	2.681LysGly: 2.681 ± 0.07	0.661LysHis: 0.661 ± 0.035	1.526LysIle: 1.526 ± 0.045	1.352LysLys: 1.352 ± 0.061	3.438LysLeu: 3.438 ± 0.068	0.849LysMet: 0.849 ± 0.036	0.897LysAsn: 0.897 ± 0.033	2.097LysPro: 2.097 ± 0.059	1.093LysGln: 1.093 ± 0.041	2.573LysArg: 2.573 ± 0.062	1.807LysSer: 1.807 ± 0.06	1.873LysThr: 1.873 ± 0.052	2.286LysVal: 2.286 ± 0.065	0.45LysTrp: 0.45 ± 0.027	0.672LysTyr: 0.672 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	13.619LeuAla: 13.619 ± 0.174	0.732LeuCys: 0.732 ± 0.033	6.433LeuAsp: 6.433 ± 0.102	5.266LeuGlu: 5.266 ± 0.1	3.423LeuPhe: 3.423 ± 0.08	8.001LeuGly: 8.001 ± 0.101	1.726LeuHis: 1.726 ± 0.055	4.205LeuIle: 4.205 ± 0.069	2.983LeuLys: 2.983 ± 0.074	9.043LeuLeu: 9.043 ± 0.153	2.232LeuMet: 2.232 ± 0.054	2.237LeuAsn: 2.237 ± 0.052	5.416LeuPro: 5.416 ± 0.08	2.632LeuGln: 2.632 ± 0.063	6.488LeuArg: 6.488 ± 0.101	5.775LeuSer: 5.775 ± 0.088	5.527LeuThr: 5.527 ± 0.086	7.207LeuVal: 7.207 ± 0.118	1.098LeuTrp: 1.098 ± 0.04	1.802LeuTyr: 1.802 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	3.334MetAla: 3.334 ± 0.066	0.149MetCys: 0.149 ± 0.015	1.435MetAsp: 1.435 ± 0.045	1.383MetGlu: 1.383 ± 0.044	0.691MetPhe: 0.691 ± 0.033	2.118MetGly: 2.118 ± 0.054	0.454MetHis: 0.454 ± 0.025	1.257MetIle: 1.257 ± 0.041	0.986MetLys: 0.986 ± 0.037	2.837MetLeu: 2.837 ± 0.064	0.692MetMet: 0.692 ± 0.031	0.832MetAsn: 0.832 ± 0.031	1.525MetPro: 1.525 ± 0.041	0.889MetGln: 0.889 ± 0.037	1.935MetArg: 1.935 ± 0.051	1.487MetSer: 1.487 ± 0.043	1.902MetThr: 1.902 ± 0.049	1.79MetVal: 1.79 ± 0.048	0.211MetTrp: 0.211 ± 0.018	0.27MetTyr: 0.27 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.497AsnAla: 3.497 ± 0.068	0.232AsnCys: 0.232 ± 0.017	1.627AsnAsp: 1.627 ± 0.041	1.34AsnGlu: 1.34 ± 0.042	1.032AsnPhe: 1.032 ± 0.041	2.583AsnGly: 2.583 ± 0.068	0.532AsnHis: 0.532 ± 0.025	1.448AsnIle: 1.448 ± 0.045	0.732AsnLys: 0.732 ± 0.029	2.514AsnLeu: 2.514 ± 0.063	0.606AsnMet: 0.606 ± 0.028	0.694AsnAsn: 0.694 ± 0.033	1.88AsnPro: 1.88 ± 0.059	0.767AsnGln: 0.767 ± 0.03	2.012AsnArg: 2.012 ± 0.051	1.451AsnSer: 1.451 ± 0.05	1.371AsnThr: 1.371 ± 0.043	1.942AsnVal: 1.942 ± 0.059	0.404AsnTrp: 0.404 ± 0.026	0.73AsnTyr: 0.73 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	6.362ProAla: 6.362 ± 0.108	0.321ProCys: 0.321 ± 0.021	4.183ProAsp: 4.183 ± 0.08	3.668ProGlu: 3.668 ± 0.065	1.87ProPhe: 1.87 ± 0.049	4.443ProGly: 4.443 ± 0.084	0.946ProHis: 0.946 ± 0.039	2.396ProIle: 2.396 ± 0.063	1.648ProLys: 1.648 ± 0.055	4.529ProLeu: 4.529 ± 0.084	1.258ProMet: 1.258 ± 0.04	1.286ProAsn: 1.286 ± 0.043	2.544ProPro: 2.544 ± 0.096	1.722ProGln: 1.722 ± 0.045	2.742ProArg: 2.742 ± 0.054	2.633ProSer: 2.633 ± 0.06	2.596ProThr: 2.596 ± 0.061	4.175ProVal: 4.175 ± 0.08	0.599ProTrp: 0.599 ± 0.029	1.098ProTyr: 1.098 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.922GlnAla: 3.922 ± 0.076	0.224GlnCys: 0.224 ± 0.019	1.84GlnAsp: 1.84 ± 0.047	1.537GlnGlu: 1.537 ± 0.048	1.205GlnPhe: 1.205 ± 0.044	2.321GlnGly: 2.321 ± 0.061	0.602GlnHis: 0.602 ± 0.032	1.785GlnIle: 1.785 ± 0.047	0.952GlnLys: 0.952 ± 0.032	3.235GlnLeu: 3.235 ± 0.07	0.857GlnMet: 0.857 ± 0.035	0.904GlnAsn: 0.904 ± 0.032	1.787GlnPro: 1.787 ± 0.062	1.36GlnGln: 1.36 ± 0.048	2.453GlnArg: 2.453 ± 0.049	1.847GlnSer: 1.847 ± 0.048	1.89GlnThr: 1.89 ± 0.056	2.253GlnVal: 2.253 ± 0.053	0.411GlnTrp: 0.411 ± 0.023	0.7GlnTyr: 0.7 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	7.941ArgAla: 7.941 ± 0.118	0.439ArgCys: 0.439 ± 0.026	4.388ArgAsp: 4.388 ± 0.084	4.339ArgGlu: 4.339 ± 0.077	2.943ArgPhe: 2.943 ± 0.067	4.98ArgGly: 4.98 ± 0.089	1.462ArgHis: 1.462 ± 0.048	4.086ArgIle: 4.086 ± 0.076	2.541ArgLys: 2.541 ± 0.055	7.207ArgLeu: 7.207 ± 0.133	2.099ArgMet: 2.099 ± 0.059	2.001ArgAsn: 2.001 ± 0.046	3.2ArgPro: 3.2 ± 0.069	2.411ArgGln: 2.411 ± 0.06	5.16ArgArg: 5.16 ± 0.106	3.749ArgSer: 3.749 ± 0.069	3.517ArgThr: 3.517 ± 0.066	4.534ArgVal: 4.534 ± 0.072	1.102ArgTrp: 1.102 ± 0.037	1.662ArgTyr: 1.662 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.457SerAla: 6.457 ± 0.096	0.44SerCys: 0.44 ± 0.025	3.603SerAsp: 3.603 ± 0.063	2.958SerGlu: 2.958 ± 0.062	2.136SerPhe: 2.136 ± 0.052	5.72SerGly: 5.72 ± 0.08	0.932SerHis: 0.932 ± 0.039	2.678SerIle: 2.678 ± 0.059	1.598SerLys: 1.598 ± 0.05	4.956SerLeu: 4.956 ± 0.069	1.262SerMet: 1.262 ± 0.043	1.515SerAsn: 1.515 ± 0.045	2.704SerPro: 2.704 ± 0.055	1.782SerGln: 1.782 ± 0.049	3.555SerArg: 3.555 ± 0.062	2.896SerSer: 2.896 ± 0.067	2.678SerThr: 2.678 ± 0.059	3.638SerVal: 3.638 ± 0.066	0.774SerTrp: 0.774 ± 0.029	1.246SerTyr: 1.246 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	6.77ThrAla: 6.77 ± 0.109	0.379ThrCys: 0.379 ± 0.024	3.448ThrAsp: 3.448 ± 0.069	2.786ThrGlu: 2.786 ± 0.072	1.847ThrPhe: 1.847 ± 0.047	5.611ThrGly: 5.611 ± 0.095	0.924ThrHis: 0.924 ± 0.037	2.994ThrIle: 2.994 ± 0.059	1.602ThrLys: 1.602 ± 0.046	5.62ThrLeu: 5.62 ± 0.087	1.377ThrMet: 1.377 ± 0.041	1.518ThrAsn: 1.518 ± 0.059	3.314ThrPro: 3.314 ± 0.072	1.671ThrGln: 1.671 ± 0.049	3.49ThrArg: 3.49 ± 0.071	2.892ThrSer: 2.892 ± 0.061	2.894ThrThr: 2.894 ± 0.07	4.136ThrVal: 4.136 ± 0.077	0.541ThrTrp: 0.541 ± 0.028	1.252ThrTyr: 1.252 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	8.653ValAla: 8.653 ± 0.115	0.542ValCys: 0.542 ± 0.024	4.35ValAsp: 4.35 ± 0.086	4.486ValGlu: 4.486 ± 0.079	2.302ValPhe: 2.302 ± 0.065	5.389ValGly: 5.389 ± 0.087	1.216ValHis: 1.216 ± 0.04	3.577ValIle: 3.577 ± 0.073	2.107ValLys: 2.107 ± 0.059	6.812ValLeu: 6.812 ± 0.119	1.821ValMet: 1.821 ± 0.051	1.92ValAsn: 1.92 ± 0.058	3.767ValPro: 3.767 ± 0.068	2.058ValGln: 2.058 ± 0.048	4.599ValArg: 4.599 ± 0.082	4.084ValSer: 4.084 ± 0.076	4.535ValThr: 4.535 ± 0.088	5.011ValVal: 5.011 ± 0.086	0.831ValTrp: 0.831 ± 0.032	1.28ValTyr: 1.28 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.278TrpAla: 1.278 ± 0.048	0.125TrpCys: 0.125 ± 0.013	0.732TrpAsp: 0.732 ± 0.028	0.609TrpGlu: 0.609 ± 0.027	0.587TrpPhe: 0.587 ± 0.029	0.905TrpGly: 0.905 ± 0.034	0.341TrpHis: 0.341 ± 0.024	0.601TrpIle: 0.601 ± 0.032	0.421TrpLys: 0.421 ± 0.027	1.76TrpLeu: 1.76 ± 0.054	0.359TrpMet: 0.359 ± 0.022	0.479TrpAsn: 0.479 ± 0.026	0.65TrpPro: 0.65 ± 0.028	0.654TrpGln: 0.654 ± 0.03	1.187TrpArg: 1.187 ± 0.036	0.811TrpSer: 0.811 ± 0.033	0.677TrpThr: 0.677 ± 0.028	0.761TrpVal: 0.761 ± 0.028	0.254TrpTrp: 0.254 ± 0.02	0.257TrpTyr: 0.257 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.477TyrAla: 2.477 ± 0.061	0.215TyrCys: 0.215 ± 0.014	1.705TyrAsp: 1.705 ± 0.06	1.23TyrGlu: 1.23 ± 0.036	0.844TyrPhe: 0.844 ± 0.03	2.049TyrGly: 2.049 ± 0.046	0.46TyrHis: 0.46 ± 0.025	0.937TyrIle: 0.937 ± 0.033	0.576TyrLys: 0.576 ± 0.029	1.978TyrLeu: 1.978 ± 0.053	0.384TyrMet: 0.384 ± 0.022	0.615TyrAsn: 0.615 ± 0.027	0.984TyrPro: 0.984 ± 0.043	0.634TyrGln: 0.634 ± 0.027	1.865TyrArg: 1.865 ± 0.048	1.262TyrSer: 1.262 ± 0.041	1.112TyrThr: 1.112 ± 0.044	1.402TyrVal: 1.402 ± 0.044	0.342TyrTrp: 0.342 ± 0.022	0.574TyrTyr: 0.574 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2539 proteins (800198 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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