Amino acid dipepetide frequency for Tomato severe leaf curl virus-[Guatemala 96-1]

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.855AlaAla: 5.855 ± 4.098
1.171AlaCys: 1.171 ± 0.935
3.513AlaAsp: 3.513 ± 1.609
3.513AlaGlu: 3.513 ± 1.557
0.0AlaPhe: 0.0 ± 0.0
4.684AlaGly: 4.684 ± 1.684
1.171AlaHis: 1.171 ± 0.935
2.342AlaIle: 2.342 ± 0.842
4.684AlaLys: 4.684 ± 2.234
5.855AlaLeu: 5.855 ± 1.659
1.171AlaMet: 1.171 ± 0.734
3.513AlaAsn: 3.513 ± 1.615
2.342AlaPro: 2.342 ± 0.842
2.342AlaGln: 2.342 ± 1.639
4.684AlaArg: 4.684 ± 3.279
5.855AlaSer: 5.855 ± 1.244
3.513AlaThr: 3.513 ± 2.034
3.513AlaVal: 3.513 ± 1.609
2.342AlaTrp: 2.342 ± 1.869
1.171AlaTyr: 1.171 ± 1.355
0.0AlaXaa: 0.0 ± 0.0
Cys
1.171CysAla: 1.171 ± 1.37
0.0CysCys: 0.0 ± 0.0
1.171CysAsp: 1.171 ± 0.82
2.342CysGlu: 2.342 ± 0.842
0.0CysPhe: 0.0 ± 0.0
2.342CysGly: 2.342 ± 2.74
0.0CysHis: 0.0 ± 0.0
2.342CysIle: 2.342 ± 1.453
2.342CysLys: 2.342 ± 0.842
1.171CysLeu: 1.171 ± 0.82
0.0CysMet: 0.0 ± 0.0
1.171CysAsn: 1.171 ± 0.82
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.171CysArg: 1.171 ± 1.37
1.171CysSer: 1.171 ± 1.37
1.171CysThr: 1.171 ± 0.935
1.171CysVal: 1.171 ± 0.935
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.513AspAla: 3.513 ± 1.374
1.171AspCys: 1.171 ± 1.37
5.855AspAsp: 5.855 ± 2.773
3.513AspGlu: 3.513 ± 1.374
2.342AspPhe: 2.342 ± 0.842
1.171AspGly: 1.171 ± 0.82
0.0AspHis: 0.0 ± 0.0
7.026AspIle: 7.026 ± 2.219
1.171AspLys: 1.171 ± 0.935
4.684AspLeu: 4.684 ± 2.265
0.0AspMet: 0.0 ± 0.0
2.342AspAsn: 2.342 ± 1.478
2.342AspPro: 2.342 ± 1.241
1.171AspGln: 1.171 ± 1.355
3.513AspArg: 3.513 ± 2.034
2.342AspSer: 2.342 ± 1.453
1.171AspThr: 1.171 ± 0.82
3.513AspVal: 3.513 ± 1.579
2.342AspTrp: 2.342 ± 1.639
2.342AspTyr: 2.342 ± 1.639
0.0AspXaa: 0.0 ± 0.0
Glu
4.684GluAla: 4.684 ± 2.1
0.0GluCys: 0.0 ± 0.0
1.171GluAsp: 1.171 ± 1.355
2.342GluGlu: 2.342 ± 1.639
1.171GluPhe: 1.171 ± 1.37
5.855GluGly: 5.855 ± 1.671
2.342GluHis: 2.342 ± 1.254
0.0GluIle: 0.0 ± 0.0
1.171GluLys: 1.171 ± 0.82
1.171GluLeu: 1.171 ± 0.82
2.342GluMet: 2.342 ± 1.639
7.026GluAsn: 7.026 ± 2.803
2.342GluPro: 2.342 ± 0.842
2.342GluGln: 2.342 ± 1.869
2.342GluArg: 2.342 ± 1.639
4.684GluSer: 4.684 ± 1.58
0.0GluThr: 0.0 ± 0.0
1.171GluVal: 1.171 ± 1.355
1.171GluTrp: 1.171 ± 0.82
1.171GluTyr: 1.171 ± 0.82
0.0GluXaa: 0.0 ± 0.0
Phe
1.171PheAla: 1.171 ± 1.355
1.171PheCys: 1.171 ± 0.935
3.513PheAsp: 3.513 ± 1.579
0.0PheGlu: 0.0 ± 0.0
1.171PhePhe: 1.171 ± 0.82
2.342PheGly: 2.342 ± 0.842
2.342PheHis: 2.342 ± 1.254
3.513PheIle: 3.513 ± 1.609
2.342PheLys: 2.342 ± 2.709
3.513PheLeu: 3.513 ± 2.459
0.0PheMet: 0.0 ± 0.0
3.513PheAsn: 3.513 ± 0.991
2.342PhePro: 2.342 ± 1.639
1.171PheGln: 1.171 ± 0.82
2.342PheArg: 2.342 ± 1.254
0.0PheSer: 0.0 ± 0.0
3.513PheThr: 3.513 ± 1.557
0.0PheVal: 0.0 ± 0.0
3.513PheTrp: 3.513 ± 2.059
5.855PheTyr: 5.855 ± 3.059
0.0PheXaa: 0.0 ± 0.0
Gly
3.513GlyAla: 3.513 ± 1.615
2.342GlyCys: 2.342 ± 1.478
2.342GlyAsp: 2.342 ± 1.639
5.855GlyGlu: 5.855 ± 1.978
2.342GlyPhe: 2.342 ± 1.254
4.684GlyGly: 4.684 ± 1.116
1.171GlyHis: 1.171 ± 0.82
2.342GlyIle: 2.342 ± 0.842
9.368GlyLys: 9.368 ± 3.917
0.0GlyLeu: 0.0 ± 0.0
0.0GlyMet: 0.0 ± 0.0
1.171GlyAsn: 1.171 ± 0.935
4.684GlyPro: 4.684 ± 1.504
3.513GlyGln: 3.513 ± 1.579
2.342GlyArg: 2.342 ± 1.254
1.171GlySer: 1.171 ± 1.37
7.026GlyThr: 7.026 ± 2.073
1.171GlyVal: 1.171 ± 1.355
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
3.513HisAla: 3.513 ± 1.579
2.342HisCys: 2.342 ± 1.254
2.342HisAsp: 2.342 ± 1.478
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.171HisGly: 1.171 ± 1.37
1.171HisHis: 1.171 ± 1.37
2.342HisIle: 2.342 ± 1.923
3.513HisLys: 3.513 ± 1.847
2.342HisLeu: 2.342 ± 1.639
0.0HisMet: 0.0 ± 0.0
5.855HisAsn: 5.855 ± 2.952
3.513HisPro: 3.513 ± 1.615
2.342HisGln: 2.342 ± 1.478
2.342HisArg: 2.342 ± 1.478
1.171HisSer: 1.171 ± 1.355
2.342HisThr: 2.342 ± 1.869
3.513HisVal: 3.513 ± 2.034
1.171HisTrp: 1.171 ± 0.82
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.171IleAla: 1.171 ± 1.37
1.171IleCys: 1.171 ± 1.355
3.513IleAsp: 3.513 ± 2.495
3.513IleGlu: 3.513 ± 2.459
2.342IlePhe: 2.342 ± 1.639
1.171IleGly: 1.171 ± 0.82
0.0IleHis: 0.0 ± 0.0
4.684IleIle: 4.684 ± 2.232
5.855IleLys: 5.855 ± 0.733
1.171IleLeu: 1.171 ± 0.935
0.0IleMet: 0.0 ± 0.0
2.342IleAsn: 2.342 ± 2.709
3.513IlePro: 3.513 ± 1.615
2.342IleGln: 2.342 ± 1.241
7.026IleArg: 7.026 ± 1.87
4.684IleSer: 4.684 ± 1.504
4.684IleThr: 4.684 ± 1.093
3.513IleVal: 3.513 ± 1.374
3.513IleTrp: 3.513 ± 2.65
4.684IleTyr: 4.684 ± 2.907
0.0IleXaa: 0.0 ± 0.0
Lys
7.026LysAla: 7.026 ± 2.182
0.0LysCys: 0.0 ± 0.0
7.026LysAsp: 7.026 ± 4.918
3.513LysGlu: 3.513 ± 2.459
5.855LysPhe: 5.855 ± 2.349
1.171LysGly: 1.171 ± 0.82
2.342LysHis: 2.342 ± 1.254
3.513LysIle: 3.513 ± 2.059
0.0LysLys: 0.0 ± 0.0
1.171LysLeu: 1.171 ± 0.935
2.342LysMet: 2.342 ± 1.062
2.342LysAsn: 2.342 ± 0.842
4.684LysPro: 4.684 ± 1.116
0.0LysGln: 0.0 ± 0.0
4.684LysArg: 4.684 ± 2.836
7.026LysSer: 7.026 ± 2.219
3.513LysThr: 3.513 ± 1.374
5.855LysVal: 5.855 ± 3.362
0.0LysTrp: 0.0 ± 0.0
3.513LysTyr: 3.513 ± 0.991
0.0LysXaa: 0.0 ± 0.0
Leu
1.171LeuAla: 1.171 ± 0.82
1.171LeuCys: 1.171 ± 0.82
4.684LeuAsp: 4.684 ± 1.58
2.342LeuGlu: 2.342 ± 1.241
3.513LeuPhe: 3.513 ± 1.615
4.684LeuGly: 4.684 ± 1.141
3.513LeuHis: 3.513 ± 1.609
2.342LeuIle: 2.342 ± 1.639
5.855LeuLys: 5.855 ± 1.276
4.684LeuLeu: 4.684 ± 2.207
1.171LeuMet: 1.171 ± 0.935
4.684LeuAsn: 4.684 ± 1.141
3.513LeuPro: 3.513 ± 2.495
2.342LeuGln: 2.342 ± 1.254
2.342LeuArg: 2.342 ± 1.453
5.855LeuSer: 5.855 ± 2.754
2.342LeuThr: 2.342 ± 1.639
2.342LeuVal: 2.342 ± 1.453
0.0LeuTrp: 0.0 ± 0.0
4.684LeuTyr: 4.684 ± 2.219
0.0LeuXaa: 0.0 ± 0.0
Met
2.342MetAla: 2.342 ± 1.869
1.171MetCys: 1.171 ± 0.935
3.513MetAsp: 3.513 ± 2.034
0.0MetGlu: 0.0 ± 0.0
2.342MetPhe: 2.342 ± 1.869
0.0MetGly: 0.0 ± 0.0
1.171MetHis: 1.171 ± 0.935
0.0MetIle: 0.0 ± 0.0
1.171MetLys: 1.171 ± 0.82
1.171MetLeu: 1.171 ± 0.82
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.342MetPro: 2.342 ± 0.842
2.342MetGln: 2.342 ± 1.254
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.171MetTrp: 1.171 ± 0.82
1.171MetTyr: 1.171 ± 0.935
0.0MetXaa: 0.0 ± 0.0
Asn
7.026AsnAla: 7.026 ± 3.673
2.342AsnCys: 2.342 ± 1.254
0.0AsnAsp: 0.0 ± 0.0
3.513AsnGlu: 3.513 ± 1.579
1.171AsnPhe: 1.171 ± 0.82
1.171AsnGly: 1.171 ± 0.935
8.197AsnHis: 8.197 ± 4.017
4.684AsnIle: 4.684 ± 2.1
2.342AsnLys: 2.342 ± 1.639
5.855AsnLeu: 5.855 ± 2.482
1.171AsnMet: 1.171 ± 1.657
2.342AsnAsn: 2.342 ± 1.453
4.684AsnPro: 4.684 ± 1.093
2.342AsnGln: 2.342 ± 1.478
2.342AsnArg: 2.342 ± 1.453
5.855AsnSer: 5.855 ± 0.733
2.342AsnThr: 2.342 ± 1.923
5.855AsnVal: 5.855 ± 2.754
0.0AsnTrp: 0.0 ± 0.0
3.513AsnTyr: 3.513 ± 1.609
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
1.171ProCys: 1.171 ± 0.935
2.342ProAsp: 2.342 ± 0.842
2.342ProGlu: 2.342 ± 1.639
1.171ProPhe: 1.171 ± 0.82
1.171ProGly: 1.171 ± 0.82
3.513ProHis: 3.513 ± 1.615
2.342ProIle: 2.342 ± 1.241
7.026ProLys: 7.026 ± 1.939
3.513ProLeu: 3.513 ± 1.557
2.342ProMet: 2.342 ± 1.869
7.026ProAsn: 7.026 ± 3.684
2.342ProPro: 2.342 ± 1.254
5.855ProGln: 5.855 ± 3.704
5.855ProArg: 5.855 ± 2.352
3.513ProSer: 3.513 ± 1.022
1.171ProThr: 1.171 ± 0.82
2.342ProVal: 2.342 ± 0.842
3.513ProTrp: 3.513 ± 1.374
1.171ProTyr: 1.171 ± 0.935
0.0ProXaa: 0.0 ± 0.0
Gln
5.855GlnAla: 5.855 ± 2.042
2.342GlnCys: 2.342 ± 1.254
1.171GlnAsp: 1.171 ± 1.37
3.513GlnGlu: 3.513 ± 1.022
0.0GlnPhe: 0.0 ± 0.0
0.0GlnGly: 0.0 ± 0.0
2.342GlnHis: 2.342 ± 2.74
3.513GlnIle: 3.513 ± 2.465
2.342GlnLys: 2.342 ± 1.639
2.342GlnLeu: 2.342 ± 1.254
0.0GlnMet: 0.0 ± 0.0
3.513GlnAsn: 3.513 ± 1.615
2.342GlnPro: 2.342 ± 2.74
1.171GlnGln: 1.171 ± 1.37
1.171GlnArg: 1.171 ± 0.935
4.684GlnSer: 4.684 ± 1.504
0.0GlnThr: 0.0 ± 0.0
2.342GlnVal: 2.342 ± 1.869
0.0GlnTrp: 0.0 ± 0.0
3.513GlnTyr: 3.513 ± 1.374
0.0GlnXaa: 0.0 ± 0.0
Arg
4.684ArgAla: 4.684 ± 1.093
0.0ArgCys: 0.0 ± 0.0
4.684ArgAsp: 4.684 ± 2.455
2.342ArgGlu: 2.342 ± 1.254
8.197ArgPhe: 8.197 ± 3.501
4.684ArgGly: 4.684 ± 2.957
1.171ArgHis: 1.171 ± 0.935
5.855ArgIle: 5.855 ± 3.059
3.513ArgLys: 3.513 ± 1.847
4.684ArgLeu: 4.684 ± 1.093
0.0ArgMet: 0.0 ± 0.0
1.171ArgAsn: 1.171 ± 0.82
4.684ArgPro: 4.684 ± 1.684
0.0ArgGln: 0.0 ± 0.0
3.513ArgArg: 3.513 ± 1.022
3.513ArgSer: 3.513 ± 0.991
4.684ArgThr: 4.684 ± 1.473
4.684ArgVal: 4.684 ± 1.684
0.0ArgTrp: 0.0 ± 0.0
1.171ArgTyr: 1.171 ± 0.935
0.0ArgXaa: 0.0 ± 0.0
Ser
2.342SerAla: 2.342 ± 1.639
0.0SerCys: 0.0 ± 0.0
1.171SerAsp: 1.171 ± 0.935
0.0SerGlu: 0.0 ± 0.0
4.684SerPhe: 4.684 ± 2.507
7.026SerGly: 7.026 ± 2.583
2.342SerHis: 2.342 ± 1.453
5.855SerIle: 5.855 ± 2.46
0.0SerLys: 0.0 ± 0.0
2.342SerLeu: 2.342 ± 1.923
0.0SerMet: 0.0 ± 0.0
9.368SerAsn: 9.368 ± 2.182
2.342SerPro: 2.342 ± 1.478
0.0SerGln: 0.0 ± 0.0
7.026SerArg: 7.026 ± 1.87
8.197SerSer: 8.197 ± 6.318
4.684SerThr: 4.684 ± 2.265
7.026SerVal: 7.026 ± 2.803
0.0SerTrp: 0.0 ± 0.0
4.684SerTyr: 4.684 ± 1.093
0.0SerXaa: 0.0 ± 0.0
Thr
2.342ThrAla: 2.342 ± 1.453
0.0ThrCys: 0.0 ± 0.0
1.171ThrAsp: 1.171 ± 0.935
1.171ThrGlu: 1.171 ± 0.935
1.171ThrPhe: 1.171 ± 0.82
5.855ThrGly: 5.855 ± 2.26
4.684ThrHis: 4.684 ± 1.504
1.171ThrIle: 1.171 ± 1.355
3.513ThrLys: 3.513 ± 1.615
3.513ThrLeu: 3.513 ± 1.374
1.171ThrMet: 1.171 ± 0.82
4.684ThrAsn: 4.684 ± 1.093
5.855ThrPro: 5.855 ± 2.287
1.171ThrGln: 1.171 ± 1.37
2.342ThrArg: 2.342 ± 1.453
1.171ThrSer: 1.171 ± 1.355
2.342ThrThr: 2.342 ± 2.709
2.342ThrVal: 2.342 ± 1.478
0.0ThrTrp: 0.0 ± 0.0
3.513ThrTyr: 3.513 ± 1.609
0.0ThrXaa: 0.0 ± 0.0
Val
1.171ValAla: 1.171 ± 0.82
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
1.171ValGlu: 1.171 ± 1.355
2.342ValPhe: 2.342 ± 1.453
2.342ValGly: 2.342 ± 1.869
0.0ValHis: 0.0 ± 0.0
3.513ValIle: 3.513 ± 2.465
5.855ValLys: 5.855 ± 2.352
4.684ValLeu: 4.684 ± 2.219
3.513ValMet: 3.513 ± 2.804
3.513ValAsn: 3.513 ± 1.579
4.684ValPro: 4.684 ± 1.093
5.855ValGln: 5.855 ± 0.733
2.342ValArg: 2.342 ± 1.453
4.684ValSer: 4.684 ± 1.093
2.342ValThr: 2.342 ± 1.869
2.342ValVal: 2.342 ± 0.842
0.0ValTrp: 0.0 ± 0.0
5.855ValTyr: 5.855 ± 2.352
0.0ValXaa: 0.0 ± 0.0
Trp
2.342TrpAla: 2.342 ± 1.639
0.0TrpCys: 0.0 ± 0.0
1.171TrpAsp: 1.171 ± 1.37
1.171TrpGlu: 1.171 ± 1.355
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.171TrpLys: 1.171 ± 0.82
1.171TrpLeu: 1.171 ± 0.935
1.171TrpMet: 1.171 ± 0.935
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.171TrpGln: 1.171 ± 0.82
3.513TrpArg: 3.513 ± 2.804
1.171TrpSer: 1.171 ± 0.82
2.342TrpThr: 2.342 ± 1.241
2.342TrpVal: 2.342 ± 0.842
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.342TyrAla: 2.342 ± 1.869
1.171TyrCys: 1.171 ± 0.82
1.171TyrAsp: 1.171 ± 0.935
2.342TyrGlu: 2.342 ± 1.869
3.513TyrPhe: 3.513 ± 0.991
3.513TyrGly: 3.513 ± 1.579
3.513TyrHis: 3.513 ± 1.609
3.513TyrIle: 3.513 ± 1.374
2.342TyrLys: 2.342 ± 1.639
8.197TyrLeu: 8.197 ± 4.917
2.342TyrMet: 2.342 ± 1.237
2.342TyrAsn: 2.342 ± 0.842
1.171TyrPro: 1.171 ± 0.82
4.684TyrGln: 4.684 ± 1.141
2.342TyrArg: 2.342 ± 1.869
2.342TyrSer: 2.342 ± 1.241
0.0TyrThr: 0.0 ± 0.0
1.171TyrVal: 1.171 ± 1.355
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (855 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski