Simian-Human immunodeficiency virus

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus; Primate lentivirus group; unclassified Primate lentivirus group

Average proteome isoelectric point is 7.06

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 9 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q77Y21|Q77Y21_9PLVG Protein Rev OS=Simian-Human immunodeficiency virus OX=57667 GN=rev PE=3 SV=1
MM1 pKa = 7.23QPIQIAIVALVVAIIIAIVVWSIVIIEE28 pKa = 3.96YY29 pKa = 10.52RR30 pKa = 11.84KK31 pKa = 9.52ILRR34 pKa = 11.84QRR36 pKa = 11.84KK37 pKa = 8.02IDD39 pKa = 3.69RR40 pKa = 11.84LIDD43 pKa = 3.54RR44 pKa = 11.84LIEE47 pKa = 4.08RR48 pKa = 11.84AEE50 pKa = 4.06DD51 pKa = 3.39SGNEE55 pKa = 4.05SEE57 pKa = 5.18GEE59 pKa = 3.65ISALVEE65 pKa = 3.91MGVEE69 pKa = 4.38MGHH72 pKa = 6.17HH73 pKa = 6.54APWDD77 pKa = 3.7VDD79 pKa = 3.84DD80 pKa = 4.78LL81 pKa = 4.6

Molecular weight: 9.17 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q77Y31|Q77Y31_9PLVG Vpx OS=Simian-Human immunodeficiency virus OX=57667 GN=vpx PE=4 SV=1
MM1 pKa = 7.59EE2 pKa = 4.69EE3 pKa = 3.94EE4 pKa = 4.36KK5 pKa = 10.69RR6 pKa = 11.84WIAVPTWRR14 pKa = 11.84IPEE17 pKa = 4.05RR18 pKa = 11.84LEE20 pKa = 3.78RR21 pKa = 11.84WHH23 pKa = 7.58SLIKK27 pKa = 9.52YY28 pKa = 9.28LKK30 pKa = 10.09YY31 pKa = 9.27KK32 pKa = 10.34TKK34 pKa = 10.64DD35 pKa = 3.51LQKK38 pKa = 10.04VCYY41 pKa = 9.65VPHH44 pKa = 6.74FKK46 pKa = 10.94VGWAWWTCSRR56 pKa = 11.84VIFPLQEE63 pKa = 4.15GSHH66 pKa = 7.43LEE68 pKa = 4.16VQGYY72 pKa = 6.63WHH74 pKa = 6.92LTPEE78 pKa = 4.54KK79 pKa = 10.18GWLSTYY85 pKa = 10.32AVRR88 pKa = 11.84ITWYY92 pKa = 10.65SKK94 pKa = 11.12NFWTDD99 pKa = 2.63VTPNYY104 pKa = 11.03ADD106 pKa = 3.6ILLHH110 pKa = 5.64STYY113 pKa = 9.94FPCFTAGEE121 pKa = 4.14VRR123 pKa = 11.84RR124 pKa = 11.84AIRR127 pKa = 11.84GEE129 pKa = 3.83QLLSCCRR136 pKa = 11.84FPRR139 pKa = 11.84AHH141 pKa = 7.46KK142 pKa = 10.04YY143 pKa = 7.97QVPSLQYY150 pKa = 10.06LALKK154 pKa = 9.88VVSDD158 pKa = 3.84VRR160 pKa = 11.84SQGEE164 pKa = 4.06NPTWKK169 pKa = 9.28QWRR172 pKa = 11.84RR173 pKa = 11.84DD174 pKa = 3.27NRR176 pKa = 11.84RR177 pKa = 11.84GLRR180 pKa = 11.84MAKK183 pKa = 9.78QNSRR187 pKa = 11.84GDD189 pKa = 3.48KK190 pKa = 10.07QRR192 pKa = 11.84GGKK195 pKa = 9.37PPTKK199 pKa = 10.0GANFPGLAKK208 pKa = 10.7VLGILAA214 pKa = 4.45

Molecular weight: 25.27 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9

0

9

2542

81

1059

282.4

32.13

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.94 ± 0.449

1.849 ± 0.474

4.249 ± 0.482

8.104 ± 0.655

2.478 ± 0.419

8.104 ± 0.394

2.518 ± 0.279

5.901 ± 0.891

7.12 ± 0.937

8.143 ± 0.513

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.4 ± 0.215

3.541 ± 0.353

6.491 ± 0.767

5.665 ± 0.583

6.491 ± 1.151

4.721 ± 0.54

4.721 ± 0.589

5.94 ± 0.604

2.675 ± 0.35

2.95 ± 0.474
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski