Amino acid dipepetide frequency for Sulfitobacter donghicola DSW-25 = KCTC 12864 = JCM 14565

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.034AlaAla: 15.034 ± 0.2
1.055AlaCys: 1.055 ± 0.033
6.702AlaAsp: 6.702 ± 0.083
7.608AlaGlu: 7.608 ± 0.091
4.227AlaPhe: 4.227 ± 0.072
9.568AlaGly: 9.568 ± 0.111
2.255AlaHis: 2.255 ± 0.054
5.804AlaIle: 5.804 ± 0.086
4.652AlaLys: 4.652 ± 0.086
12.517AlaLeu: 12.517 ± 0.122
3.625AlaMet: 3.625 ± 0.068
2.97AlaAsn: 2.97 ± 0.052
5.324AlaPro: 5.324 ± 0.089
4.942AlaGln: 4.942 ± 0.074
7.065AlaArg: 7.065 ± 0.102
5.786AlaSer: 5.786 ± 0.073
5.901AlaThr: 5.901 ± 0.093
7.834AlaVal: 7.834 ± 0.105
1.315AlaTrp: 1.315 ± 0.039
2.512AlaTyr: 2.512 ± 0.05
0.0AlaXaa: 0.0 ± 0.0
Cys
1.03CysAla: 1.03 ± 0.032
0.09CysCys: 0.09 ± 0.009
0.626CysAsp: 0.626 ± 0.027
0.477CysGlu: 0.477 ± 0.023
0.371CysPhe: 0.371 ± 0.018
0.9CysGly: 0.9 ± 0.034
0.246CysHis: 0.246 ± 0.016
0.483CysIle: 0.483 ± 0.021
0.301CysLys: 0.301 ± 0.017
0.793CysLeu: 0.793 ± 0.028
0.173CysMet: 0.173 ± 0.013
0.241CysAsn: 0.241 ± 0.015
0.486CysPro: 0.486 ± 0.023
0.229CysGln: 0.229 ± 0.018
0.443CysArg: 0.443 ± 0.021
0.498CysSer: 0.498 ± 0.024
0.497CysThr: 0.497 ± 0.026
0.616CysVal: 0.616 ± 0.022
0.118CysTrp: 0.118 ± 0.011
0.216CysTyr: 0.216 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
7.217AspAla: 7.217 ± 0.087
0.502AspCys: 0.502 ± 0.025
3.588AspAsp: 3.588 ± 0.093
3.745AspGlu: 3.745 ± 0.068
2.329AspPhe: 2.329 ± 0.045
5.504AspGly: 5.504 ± 0.116
1.39AspHis: 1.39 ± 0.041
3.431AspIle: 3.431 ± 0.052
1.941AspLys: 1.941 ± 0.042
6.156AspLeu: 6.156 ± 0.084
1.803AspMet: 1.803 ± 0.045
1.509AspAsn: 1.509 ± 0.046
3.347AspPro: 3.347 ± 0.071
2.181AspGln: 2.181 ± 0.038
3.617AspArg: 3.617 ± 0.062
2.279AspSer: 2.279 ± 0.052
3.218AspThr: 3.218 ± 0.077
4.616AspVal: 4.616 ± 0.081
1.08AspTrp: 1.08 ± 0.03
1.503AspTyr: 1.503 ± 0.035
0.0AspXaa: 0.0 ± 0.0
Glu
7.732GluAla: 7.732 ± 0.106
0.363GluCys: 0.363 ± 0.018
3.369GluAsp: 3.369 ± 0.067
3.793GluGlu: 3.793 ± 0.073
1.956GluPhe: 1.956 ± 0.047
5.048GluGly: 5.048 ± 0.078
1.206GluHis: 1.206 ± 0.036
3.819GluIle: 3.819 ± 0.067
2.658GluLys: 2.658 ± 0.055
5.302GluLeu: 5.302 ± 0.078
1.998GluMet: 1.998 ± 0.046
2.154GluAsn: 2.154 ± 0.049
2.344GluPro: 2.344 ± 0.059
2.306GluGln: 2.306 ± 0.054
3.929GluArg: 3.929 ± 0.072
2.131GluSer: 2.131 ± 0.043
4.193GluThr: 4.193 ± 0.063
4.455GluVal: 4.455 ± 0.068
0.768GluTrp: 0.768 ± 0.028
1.226GluTyr: 1.226 ± 0.036
0.0GluXaa: 0.0 ± 0.0
Phe
4.396PheAla: 4.396 ± 0.071
0.429PheCys: 0.429 ± 0.019
2.994PheAsp: 2.994 ± 0.054
2.453PheGlu: 2.453 ± 0.043
1.497PhePhe: 1.497 ± 0.043
3.819PheGly: 3.819 ± 0.063
0.768PheHis: 0.768 ± 0.029
1.799PheIle: 1.799 ± 0.041
1.213PheLys: 1.213 ± 0.038
3.377PheLeu: 3.377 ± 0.063
0.932PheMet: 0.932 ± 0.032
1.207PheAsn: 1.207 ± 0.035
1.448PhePro: 1.448 ± 0.041
1.136PheGln: 1.136 ± 0.035
1.919PheArg: 1.919 ± 0.044
2.302PheSer: 2.302 ± 0.045
2.211PheThr: 2.211 ± 0.056
2.754PheVal: 2.754 ± 0.051
0.573PheTrp: 0.573 ± 0.025
0.938PheTyr: 0.938 ± 0.033
0.0PheXaa: 0.0 ± 0.0
Gly
9.231GlyAla: 9.231 ± 0.113
0.815GlyCys: 0.815 ± 0.033
4.789GlyAsp: 4.789 ± 0.088
4.773GlyGlu: 4.773 ± 0.077
3.732GlyPhe: 3.732 ± 0.065
7.325GlyGly: 7.325 ± 0.125
1.857GlyHis: 1.857 ± 0.047
4.621GlyIle: 4.621 ± 0.072
3.55GlyLys: 3.55 ± 0.066
8.458GlyLeu: 8.458 ± 0.099
2.595GlyMet: 2.595 ± 0.054
2.428GlyAsn: 2.428 ± 0.073
3.277GlyPro: 3.277 ± 0.047
3.118GlyGln: 3.118 ± 0.054
4.956GlyArg: 4.956 ± 0.075
4.313GlySer: 4.313 ± 0.071
4.583GlyThr: 4.583 ± 0.091
6.308GlyVal: 6.308 ± 0.079
1.405GlyTrp: 1.405 ± 0.038
2.233GlyTyr: 2.233 ± 0.046
0.0GlyXaa: 0.0 ± 0.0
His
2.257HisAla: 2.257 ± 0.044
0.228HisCys: 0.228 ± 0.017
1.238HisAsp: 1.238 ± 0.037
1.099HisGlu: 1.099 ± 0.03
0.822HisPhe: 0.822 ± 0.028
1.858HisGly: 1.858 ± 0.043
0.531HisHis: 0.531 ± 0.025
1.101HisIle: 1.101 ± 0.031
0.649HisLys: 0.649 ± 0.025
2.072HisLeu: 2.072 ± 0.047
0.582HisMet: 0.582 ± 0.024
0.572HisAsn: 0.572 ± 0.023
1.295HisPro: 1.295 ± 0.041
0.643HisGln: 0.643 ± 0.025
1.176HisArg: 1.176 ± 0.035
1.041HisSer: 1.041 ± 0.029
0.912HisThr: 0.912 ± 0.032
1.461HisVal: 1.461 ± 0.041
0.316HisTrp: 0.316 ± 0.019
0.594HisTyr: 0.594 ± 0.019
0.0HisXaa: 0.0 ± 0.0
Ile
6.921IleAla: 6.921 ± 0.097
0.658IleCys: 0.658 ± 0.024
3.608IleAsp: 3.608 ± 0.068
3.803IleGlu: 3.803 ± 0.061
1.877IlePhe: 1.877 ± 0.042
4.901IleGly: 4.901 ± 0.065
1.013IleHis: 1.013 ± 0.035
2.741IleIle: 2.741 ± 0.058
1.972IleLys: 1.972 ± 0.044
4.806IleLeu: 4.806 ± 0.075
1.229IleMet: 1.229 ± 0.035
1.702IleAsn: 1.702 ± 0.043
2.442IlePro: 2.442 ± 0.05
1.383IleGln: 1.383 ± 0.033
2.952IleArg: 2.952 ± 0.053
3.566IleSer: 3.566 ± 0.056
3.322IleThr: 3.322 ± 0.062
3.812IleVal: 3.812 ± 0.07
0.809IleTrp: 0.809 ± 0.032
1.207IleTyr: 1.207 ± 0.036
0.0IleXaa: 0.0 ± 0.0
Lys
4.436LysAla: 4.436 ± 0.087
0.216LysCys: 0.216 ± 0.015
2.105LysAsp: 2.105 ± 0.045
2.164LysGlu: 2.164 ± 0.05
1.176LysPhe: 1.176 ± 0.034
3.199LysGly: 3.199 ± 0.06
0.788LysHis: 0.788 ± 0.026
2.103LysIle: 2.103 ± 0.055
1.598LysLys: 1.598 ± 0.05
3.486LysLeu: 3.486 ± 0.062
1.187LysMet: 1.187 ± 0.038
1.114LysAsn: 1.114 ± 0.033
2.055LysPro: 2.055 ± 0.05
1.243LysGln: 1.243 ± 0.034
2.635LysArg: 2.635 ± 0.054
2.323LysSer: 2.323 ± 0.049
2.47LysThr: 2.47 ± 0.043
2.595LysVal: 2.595 ± 0.055
0.463LysTrp: 0.463 ± 0.022
0.794LysTyr: 0.794 ± 0.027
0.0LysXaa: 0.0 ± 0.0
Leu
11.433LeuAla: 11.433 ± 0.116
0.946LeuCys: 0.946 ± 0.031
5.856LeuAsp: 5.856 ± 0.084
5.742LeuGlu: 5.742 ± 0.082
3.527LeuPhe: 3.527 ± 0.072
7.959LeuGly: 7.959 ± 0.089
1.876LeuHis: 1.876 ± 0.039
5.331LeuIle: 5.331 ± 0.076
3.722LeuLys: 3.722 ± 0.057
8.363LeuLeu: 8.363 ± 0.119
2.715LeuMet: 2.715 ± 0.056
2.996LeuAsn: 2.996 ± 0.06
5.16LeuPro: 5.16 ± 0.072
2.906LeuGln: 2.906 ± 0.054
6.315LeuArg: 6.315 ± 0.084
6.811LeuSer: 6.811 ± 0.082
5.745LeuThr: 5.745 ± 0.084
6.31LeuVal: 6.31 ± 0.088
1.227LeuTrp: 1.227 ± 0.038
1.875LeuTyr: 1.875 ± 0.042
0.0LeuXaa: 0.0 ± 0.0
Met
3.406MetAla: 3.406 ± 0.06
0.214MetCys: 0.214 ± 0.014
1.507MetAsp: 1.507 ± 0.037
1.455MetGlu: 1.455 ± 0.038
0.909MetPhe: 0.909 ± 0.034
2.454MetGly: 2.454 ± 0.053
0.505MetHis: 0.505 ± 0.022
1.732MetIle: 1.732 ± 0.036
1.254MetLys: 1.254 ± 0.035
2.617MetLeu: 2.617 ± 0.051
0.882MetMet: 0.882 ± 0.031
0.981MetAsn: 0.981 ± 0.031
1.511MetPro: 1.511 ± 0.034
1.092MetGln: 1.092 ± 0.029
1.934MetArg: 1.934 ± 0.043
1.948MetSer: 1.948 ± 0.04
1.96MetThr: 1.96 ± 0.043
1.859MetVal: 1.859 ± 0.042
0.268MetTrp: 0.268 ± 0.017
0.376MetTyr: 0.376 ± 0.017
0.0MetXaa: 0.0 ± 0.0
Asn
3.605AsnAla: 3.605 ± 0.061
0.303AsnCys: 0.303 ± 0.017
1.796AsnAsp: 1.796 ± 0.059
1.428AsnGlu: 1.428 ± 0.037
1.123AsnPhe: 1.123 ± 0.035
2.759AsnGly: 2.759 ± 0.065
0.622AsnHis: 0.622 ± 0.024
1.685AsnIle: 1.685 ± 0.041
0.936AsnLys: 0.936 ± 0.032
2.818AsnLeu: 2.818 ± 0.056
0.771AsnMet: 0.771 ± 0.026
0.922AsnAsn: 0.922 ± 0.036
1.981AsnPro: 1.981 ± 0.038
0.909AsnGln: 0.909 ± 0.031
1.779AsnArg: 1.779 ± 0.043
1.457AsnSer: 1.457 ± 0.041
1.618AsnThr: 1.618 ± 0.055
2.065AsnVal: 2.065 ± 0.059
0.504AsnTrp: 0.504 ± 0.019
0.747AsnTyr: 0.747 ± 0.028
0.0AsnXaa: 0.0 ± 0.0
Pro
5.172ProAla: 5.172 ± 0.092
0.334ProCys: 0.334 ± 0.018
3.69ProAsp: 3.69 ± 0.065
3.825ProGlu: 3.825 ± 0.065
1.987ProPhe: 1.987 ± 0.04
2.838ProGly: 2.838 ± 0.052
1.029ProHis: 1.029 ± 0.035
2.408ProIle: 2.408 ± 0.043
2.101ProLys: 2.101 ± 0.056
4.43ProLeu: 4.43 ± 0.073
1.288ProMet: 1.288 ± 0.039
1.61ProAsn: 1.61 ± 0.041
1.904ProPro: 1.904 ± 0.053
1.856ProGln: 1.856 ± 0.043
2.375ProArg: 2.375 ± 0.053
2.725ProSer: 2.725 ± 0.053
2.554ProThr: 2.554 ± 0.055
3.77ProVal: 3.77 ± 0.069
0.592ProTrp: 0.592 ± 0.026
1.182ProTyr: 1.182 ± 0.038
0.0ProXaa: 0.0 ± 0.0
Gln
4.066GlnAla: 4.066 ± 0.064
0.226GlnCys: 0.226 ± 0.015
1.782GlnAsp: 1.782 ± 0.044
1.987GlnGlu: 1.987 ± 0.044
1.234GlnPhe: 1.234 ± 0.036
2.718GlnGly: 2.718 ± 0.049
0.651GlnHis: 0.651 ± 0.025
2.281GlnIle: 2.281 ± 0.045
1.34GlnLys: 1.34 ± 0.037
3.148GlnLeu: 3.148 ± 0.05
1.269GlnMet: 1.269 ± 0.033
1.149GlnAsn: 1.149 ± 0.033
1.618GlnPro: 1.618 ± 0.042
1.324GlnGln: 1.324 ± 0.041
2.225GlnArg: 2.225 ± 0.05
2.136GlnSer: 2.136 ± 0.042
2.159GlnThr: 2.159 ± 0.051
2.432GlnVal: 2.432 ± 0.045
0.445GlnTrp: 0.445 ± 0.021
0.668GlnTyr: 0.668 ± 0.028
0.0GlnXaa: 0.0 ± 0.0
Arg
6.855ArgAla: 6.855 ± 0.092
0.419ArgCys: 0.419 ± 0.02
3.885ArgAsp: 3.885 ± 0.066
3.52ArgGlu: 3.52 ± 0.06
2.449ArgPhe: 2.449 ± 0.05
4.192ArgGly: 4.192 ± 0.071
1.295ArgHis: 1.295 ± 0.043
3.452ArgIle: 3.452 ± 0.055
2.559ArgLys: 2.559 ± 0.054
6.079ArgLeu: 6.079 ± 0.09
1.851ArgMet: 1.851 ± 0.043
1.82ArgAsn: 1.82 ± 0.042
2.667ArgPro: 2.667 ± 0.048
2.108ArgGln: 2.108 ± 0.042
3.948ArgArg: 3.948 ± 0.067
3.296ArgSer: 3.296 ± 0.058
2.741ArgThr: 2.741 ± 0.049
4.182ArgVal: 4.182 ± 0.068
0.845ArgTrp: 0.845 ± 0.025
1.408ArgTyr: 1.408 ± 0.037
0.0ArgXaa: 0.0 ± 0.0
Ser
5.932SerAla: 5.932 ± 0.069
0.477SerCys: 0.477 ± 0.026
3.673SerAsp: 3.673 ± 0.084
3.322SerGlu: 3.322 ± 0.054
2.472SerPhe: 2.472 ± 0.054
5.562SerGly: 5.562 ± 0.078
1.15SerHis: 1.15 ± 0.035
2.871SerIle: 2.871 ± 0.045
2.124SerLys: 2.124 ± 0.047
5.28SerLeu: 5.28 ± 0.074
1.524SerMet: 1.524 ± 0.038
1.618SerAsn: 1.618 ± 0.041
2.452SerPro: 2.452 ± 0.054
1.881SerGln: 1.881 ± 0.044
3.104SerArg: 3.104 ± 0.062
2.972SerSer: 2.972 ± 0.06
2.839SerThr: 2.839 ± 0.059
3.966SerVal: 3.966 ± 0.053
0.68SerTrp: 0.68 ± 0.026
1.467SerTyr: 1.467 ± 0.038
0.0SerXaa: 0.0 ± 0.0
Thr
6.307ThrAla: 6.307 ± 0.122
0.528ThrCys: 0.528 ± 0.033
3.277ThrAsp: 3.277 ± 0.085
2.986ThrGlu: 2.986 ± 0.064
2.08ThrPhe: 2.08 ± 0.046
5.187ThrGly: 5.187 ± 0.094
1.162ThrHis: 1.162 ± 0.032
2.978ThrIle: 2.978 ± 0.08
1.816ThrLys: 1.816 ± 0.043
6.256ThrLeu: 6.256 ± 0.107
1.392ThrMet: 1.392 ± 0.034
1.578ThrAsn: 1.578 ± 0.05
3.451ThrPro: 3.451 ± 0.059
1.928ThrGln: 1.928 ± 0.045
3.084ThrArg: 3.084 ± 0.054
3.168ThrSer: 3.168 ± 0.062
3.042ThrThr: 3.042 ± 0.072
4.217ThrVal: 4.217 ± 0.098
0.625ThrTrp: 0.625 ± 0.023
1.395ThrTyr: 1.395 ± 0.06
0.0ThrXaa: 0.0 ± 0.0
Val
7.942ValAla: 7.942 ± 0.1
0.639ValCys: 0.639 ± 0.027
4.088ValAsp: 4.088 ± 0.066
4.547ValGlu: 4.547 ± 0.081
2.833ValPhe: 2.833 ± 0.052
5.402ValGly: 5.402 ± 0.077
1.263ValHis: 1.263 ± 0.041
4.342ValIle: 4.342 ± 0.067
2.556ValLys: 2.556 ± 0.058
7.065ValLeu: 7.065 ± 0.089
2.118ValMet: 2.118 ± 0.051
2.105ValAsn: 2.105 ± 0.046
3.232ValPro: 3.232 ± 0.053
2.311ValGln: 2.311 ± 0.039
3.663ValArg: 3.663 ± 0.063
4.552ValSer: 4.552 ± 0.071
4.627ValThr: 4.627 ± 0.134
5.586ValVal: 5.586 ± 0.089
0.939ValTrp: 0.939 ± 0.028
1.461ValTyr: 1.461 ± 0.035
0.0ValXaa: 0.0 ± 0.0
Trp
1.327TrpAla: 1.327 ± 0.039
0.156TrpCys: 0.156 ± 0.013
0.794TrpAsp: 0.794 ± 0.031
0.681TrpGlu: 0.681 ± 0.022
0.575TrpPhe: 0.575 ± 0.025
1.024TrpGly: 1.024 ± 0.036
0.313TrpHis: 0.313 ± 0.019
0.756TrpIle: 0.756 ± 0.029
0.468TrpLys: 0.468 ± 0.021
1.525TrpLeu: 1.525 ± 0.041
0.421TrpMet: 0.421 ± 0.018
0.454TrpAsn: 0.454 ± 0.022
0.599TrpPro: 0.599 ± 0.026
0.596TrpGln: 0.596 ± 0.024
1.011TrpArg: 1.011 ± 0.032
0.772TrpSer: 0.772 ± 0.027
0.664TrpThr: 0.664 ± 0.024
0.907TrpVal: 0.907 ± 0.032
0.218TrpTrp: 0.218 ± 0.015
0.272TrpTyr: 0.272 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.394TyrAla: 2.394 ± 0.051
0.238TyrCys: 0.238 ± 0.015
1.592TyrAsp: 1.592 ± 0.04
1.344TyrGlu: 1.344 ± 0.037
0.989TyrPhe: 0.989 ± 0.031
2.148TyrGly: 2.148 ± 0.045
0.526TyrHis: 0.526 ± 0.021
0.986TyrIle: 0.986 ± 0.03
0.739TyrLys: 0.739 ± 0.027
2.268TyrLeu: 2.268 ± 0.048
0.507TyrMet: 0.507 ± 0.022
0.699TyrAsn: 0.699 ± 0.025
1.078TyrPro: 1.078 ± 0.034
0.766TyrGln: 0.766 ± 0.028
1.442TyrArg: 1.442 ± 0.039
1.289TyrSer: 1.289 ± 0.035
1.202TyrThr: 1.202 ± 0.06
1.528TyrVal: 1.528 ± 0.038
0.341TyrTrp: 0.341 ± 0.018
0.603TyrTyr: 0.603 ± 0.024
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3416 proteins (1055224 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski