Human papillomavirus type 96

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Betapapillomavirus; Betapapillomavirus 5

Average proteome isoelectric point is 6.21

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q6TY29|Q6TY29_9PAPI Protein E6 OS=Human papillomavirus type 96 OX=247269 GN=E6 PE=3 SV=1
MM1 pKa = 7.4IGKK4 pKa = 8.54EE5 pKa = 3.77ATIPDD10 pKa = 4.08IKK12 pKa = 11.16LEE14 pKa = 4.12LQDD17 pKa = 4.36LVLPIDD23 pKa = 3.66LHH25 pKa = 7.99CDD27 pKa = 3.25EE28 pKa = 5.54EE29 pKa = 4.48LTEE32 pKa = 4.13EE33 pKa = 3.99QSEE36 pKa = 4.28NLSEE40 pKa = 4.27STVAEE45 pKa = 4.25VEE47 pKa = 4.29PQRR50 pKa = 11.84TLYY53 pKa = 10.52KK54 pKa = 10.15IVVPCGGCDD63 pKa = 3.32SRR65 pKa = 11.84LKK67 pKa = 10.31IYY69 pKa = 10.89VSATQFGIRR78 pKa = 11.84SLEE81 pKa = 3.96DD82 pKa = 3.46LLLEE86 pKa = 4.66EE87 pKa = 5.46PSLLCPACRR96 pKa = 11.84NGRR99 pKa = 3.65

Molecular weight: 11.03 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q6TY27|Q6TY27_9PAPI Replication protein E1 OS=Human papillomavirus type 96 OX=247269 GN=E1 PE=3 SV=1
MM1 pKa = 7.45EE2 pKa = 5.84ALNQRR7 pKa = 11.84FNALEE12 pKa = 4.25DD13 pKa = 3.52QLMDD17 pKa = 3.57IYY19 pKa = 11.1EE20 pKa = 4.13QGSDD24 pKa = 3.87KK25 pKa = 11.53LEE27 pKa = 4.2DD28 pKa = 4.38QIKK31 pKa = 9.52HH32 pKa = 4.5WNFLRR37 pKa = 11.84KK38 pKa = 8.89EE39 pKa = 4.1QILLHH44 pKa = 4.74YY45 pKa = 9.87ARR47 pKa = 11.84RR48 pKa = 11.84RR49 pKa = 11.84GIMRR53 pKa = 11.84LGYY56 pKa = 9.04TPVPSLAASEE66 pKa = 4.44TKK68 pKa = 10.65AKK70 pKa = 10.62DD71 pKa = 3.47VIYY74 pKa = 10.05MVLQLEE80 pKa = 4.49KK81 pKa = 10.98LRR83 pKa = 11.84DD84 pKa = 3.63SPYY87 pKa = 10.73KK88 pKa = 10.39DD89 pKa = 4.02EE90 pKa = 4.84PWTLINTSLEE100 pKa = 4.27TYY102 pKa = 9.33RR103 pKa = 11.84APPVNCFKK111 pKa = 10.91KK112 pKa = 10.28GPQNVEE118 pKa = 4.18VIFDD122 pKa = 4.36ADD124 pKa = 3.67PEE126 pKa = 4.43NIMLYY131 pKa = 9.67TSWQFIYY138 pKa = 10.94FEE140 pKa = 4.79DD141 pKa = 5.33TDD143 pKa = 3.96GHH145 pKa = 4.56WQKK148 pKa = 9.74TEE150 pKa = 3.52GRR152 pKa = 11.84IDD154 pKa = 3.71YY155 pKa = 10.88AGLYY159 pKa = 9.04YY160 pKa = 10.84LEE162 pKa = 4.51GQLRR166 pKa = 11.84HH167 pKa = 6.02YY168 pKa = 10.36YY169 pKa = 10.63VEE171 pKa = 4.34FKK173 pKa = 10.9VDD175 pKa = 2.95ARR177 pKa = 11.84RR178 pKa = 11.84FGTSGEE184 pKa = 3.98WEE186 pKa = 3.94VRR188 pKa = 11.84FNGEE192 pKa = 4.02TIFAPVTSSSPSSYY206 pKa = 10.69EE207 pKa = 3.73EE208 pKa = 3.55VRR210 pKa = 11.84EE211 pKa = 3.99RR212 pKa = 11.84AEE214 pKa = 4.19PPDD217 pKa = 3.62VPEE220 pKa = 4.74VGTAPDD226 pKa = 3.67SGTLQTGRR234 pKa = 11.84PGTEE238 pKa = 3.47TAKK241 pKa = 10.17GRR243 pKa = 11.84RR244 pKa = 11.84YY245 pKa = 9.71GRR247 pKa = 11.84KK248 pKa = 8.69EE249 pKa = 3.69SSPTVASLRR258 pKa = 11.84VRR260 pKa = 11.84QKK262 pKa = 10.33VSRR265 pKa = 11.84STTRR269 pKa = 11.84KK270 pKa = 8.9AEE272 pKa = 4.1EE273 pKa = 3.83RR274 pKa = 11.84RR275 pKa = 11.84SRR277 pKa = 11.84SPSSGTEE284 pKa = 3.53QAGARR289 pKa = 11.84GRR291 pKa = 11.84GQRR294 pKa = 11.84GTRR297 pKa = 11.84ARR299 pKa = 11.84SRR301 pKa = 11.84TRR303 pKa = 11.84SRR305 pKa = 11.84SRR307 pKa = 11.84RR308 pKa = 11.84RR309 pKa = 11.84SRR311 pKa = 11.84SSSRR315 pKa = 11.84ARR317 pKa = 11.84SRR319 pKa = 11.84RR320 pKa = 11.84ARR322 pKa = 11.84EE323 pKa = 3.72HH324 pKa = 5.92SEE326 pKa = 3.71SRR328 pKa = 11.84GGRR331 pKa = 11.84GRR333 pKa = 11.84GAYY336 pKa = 7.47ATRR339 pKa = 11.84SRR341 pKa = 11.84SRR343 pKa = 11.84SAEE346 pKa = 3.75CRR348 pKa = 11.84SIDD351 pKa = 3.36QCGIPASQVGRR362 pKa = 11.84SVQSVGRR369 pKa = 11.84NNSSRR374 pKa = 11.84LKK376 pKa = 10.57RR377 pKa = 11.84LLDD380 pKa = 3.72EE381 pKa = 5.55ALDD384 pKa = 3.89PPVILLRR391 pKa = 11.84GEE393 pKa = 4.3PNTLKK398 pKa = 10.56CYY400 pKa = 10.27RR401 pKa = 11.84YY402 pKa = 9.37RR403 pKa = 11.84VKK405 pKa = 10.96DD406 pKa = 3.44KK407 pKa = 11.29LRR409 pKa = 11.84GSFDD413 pKa = 4.0KK414 pKa = 10.91ISTTWSWVASQGNTRR429 pKa = 11.84IGRR432 pKa = 11.84ARR434 pKa = 11.84MLLSFVSEE442 pKa = 4.09DD443 pKa = 3.44QRR445 pKa = 11.84EE446 pKa = 4.02KK447 pKa = 10.76FINVMKK453 pKa = 10.44LPKK456 pKa = 10.49GVDD459 pKa = 2.93WSFGSFDD466 pKa = 3.63SLL468 pKa = 4.27

Molecular weight: 53.62 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2645

99

608

377.9

42.69

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.444 ± 0.176

2.193 ± 0.632

5.822 ± 0.617

7.07 ± 0.619

4.008 ± 0.544

7.032 ± 0.631

1.853 ± 0.279

4.839 ± 0.76

5.104 ± 0.782

8.96 ± 0.995

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.626 ± 0.35

4.159 ± 0.771

6.276 ± 0.971

4.461 ± 0.193

7.221 ± 1.42

7.183 ± 0.829

6.011 ± 0.864

5.898 ± 0.74

1.361 ± 0.373

3.478 ± 0.236
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski