Amino acid dipepetide frequency for Beihai astro-like virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.828AlaAla: 6.828 ± 1.882
2.101AlaCys: 2.101 ± 0.849
1.576AlaAsp: 1.576 ± 0.85
2.626AlaGlu: 2.626 ± 0.994
2.626AlaPhe: 2.626 ± 0.431
5.252AlaGly: 5.252 ± 2.38
2.626AlaHis: 2.626 ± 1.076
4.202AlaIle: 4.202 ± 1.699
5.252AlaLys: 5.252 ± 0.882
7.353AlaLeu: 7.353 ± 1.546
2.101AlaMet: 2.101 ± 0.849
3.676AlaAsn: 3.676 ± 2.258
4.727AlaPro: 4.727 ± 0.589
3.151AlaGln: 3.151 ± 1.051
3.676AlaArg: 3.676 ± 0.512
3.676AlaSer: 3.676 ± 1.354
7.353AlaThr: 7.353 ± 1.898
4.202AlaVal: 4.202 ± 0.838
0.525AlaTrp: 0.525 ± 0.334
3.676AlaTyr: 3.676 ± 1.607
0.0AlaXaa: 0.0 ± 0.0
Cys
2.626CysAla: 2.626 ± 0.817
0.525CysCys: 0.525 ± 0.334
1.05CysAsp: 1.05 ± 0.538
1.05CysGlu: 1.05 ± 0.668
0.525CysPhe: 0.525 ± 0.397
3.676CysGly: 3.676 ± 0.8
0.0CysHis: 0.0 ± 0.0
1.05CysIle: 1.05 ± 0.668
1.576CysLys: 1.576 ± 1.002
1.05CysLeu: 1.05 ± 0.538
1.05CysMet: 1.05 ± 0.653
0.525CysAsn: 0.525 ± 0.334
2.626CysPro: 2.626 ± 1.164
1.05CysGln: 1.05 ± 0.653
1.05CysArg: 1.05 ± 0.35
1.576CysSer: 1.576 ± 0.597
2.101CysThr: 2.101 ± 1.336
0.525CysVal: 0.525 ± 0.334
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.202AspAla: 4.202 ± 0.981
2.101AspCys: 2.101 ± 1.076
3.676AspAsp: 3.676 ± 1.0
4.202AspGlu: 4.202 ± 1.402
2.101AspPhe: 2.101 ± 0.701
5.777AspGly: 5.777 ± 1.302
0.525AspHis: 0.525 ± 0.334
0.0AspIle: 0.0 ± 0.0
1.576AspLys: 1.576 ± 0.557
2.626AspLeu: 2.626 ± 1.505
0.0AspMet: 0.0 ± 0.0
2.101AspAsn: 2.101 ± 0.523
3.676AspPro: 3.676 ± 0.797
3.151AspGln: 3.151 ± 1.115
1.576AspArg: 1.576 ± 0.85
1.576AspSer: 1.576 ± 1.26
1.05AspThr: 1.05 ± 0.35
4.727AspVal: 4.727 ± 0.146
2.101AspTrp: 2.101 ± 1.008
1.576AspTyr: 1.576 ± 0.597
0.0AspXaa: 0.0 ± 0.0
Glu
5.777GluAla: 5.777 ± 0.816
0.525GluCys: 0.525 ± 0.334
4.202GluAsp: 4.202 ± 0.839
5.252GluGlu: 5.252 ± 0.882
0.525GluPhe: 0.525 ± 0.397
2.626GluGly: 2.626 ± 0.817
1.05GluHis: 1.05 ± 0.538
2.626GluIle: 2.626 ± 0.215
4.202GluLys: 4.202 ± 0.466
5.777GluLeu: 5.777 ± 1.689
1.576GluMet: 1.576 ± 0.351
3.676GluAsn: 3.676 ± 1.689
1.576GluPro: 1.576 ± 0.557
4.727GluGln: 4.727 ± 1.054
3.676GluArg: 3.676 ± 0.8
3.151GluSer: 3.151 ± 0.703
3.151GluThr: 3.151 ± 0.737
4.202GluVal: 4.202 ± 0.536
1.05GluTrp: 1.05 ± 0.538
2.626GluTyr: 2.626 ± 1.086
0.0GluXaa: 0.0 ± 0.0
Phe
1.05PheAla: 1.05 ± 0.653
0.525PheCys: 0.525 ± 0.668
0.0PheAsp: 0.0 ± 0.0
1.576PheGlu: 1.576 ± 1.166
0.525PhePhe: 0.525 ± 0.334
1.576PheGly: 1.576 ± 0.597
0.525PheHis: 0.525 ± 0.334
1.05PheIle: 1.05 ± 0.35
1.576PheLys: 1.576 ± 0.557
2.626PheLeu: 2.626 ± 0.994
0.525PheMet: 0.525 ± 0.334
1.576PheAsn: 1.576 ± 0.351
2.101PhePro: 2.101 ± 1.823
1.576PheGln: 1.576 ± 1.192
1.576PheArg: 1.576 ± 1.166
1.05PheSer: 1.05 ± 0.538
5.252PheThr: 5.252 ± 1.738
2.101PheVal: 2.101 ± 0.849
0.525PheTrp: 0.525 ± 0.334
1.05PheTyr: 1.05 ± 0.35
0.0PheXaa: 0.0 ± 0.0
Gly
4.202GlyAla: 4.202 ± 1.397
0.525GlyCys: 0.525 ± 0.334
3.676GlyAsp: 3.676 ± 1.0
4.727GlyGlu: 4.727 ± 0.146
2.626GlyPhe: 2.626 ± 1.076
5.777GlyGly: 5.777 ± 1.503
2.101GlyHis: 2.101 ± 0.701
3.151GlyIle: 3.151 ± 0.604
2.101GlyLys: 2.101 ± 1.336
4.727GlyLeu: 4.727 ± 1.17
5.777GlyMet: 5.777 ± 1.826
4.727GlyAsn: 4.727 ± 0.726
3.151GlyPro: 3.151 ± 1.051
4.202GlyGln: 4.202 ± 0.416
4.202GlyArg: 4.202 ± 1.046
4.202GlySer: 4.202 ± 0.838
3.676GlyThr: 3.676 ± 0.797
4.202GlyVal: 4.202 ± 1.397
1.576GlyTrp: 1.576 ± 0.351
2.626GlyTyr: 2.626 ± 0.431
0.0GlyXaa: 0.0 ± 0.0
His
1.576HisAla: 1.576 ± 1.192
2.101HisCys: 2.101 ± 1.336
2.101HisAsp: 2.101 ± 1.307
2.101HisGlu: 2.101 ± 0.208
0.525HisPhe: 0.525 ± 0.397
1.576HisGly: 1.576 ± 0.557
0.0HisHis: 0.0 ± 0.0
1.05HisIle: 1.05 ± 0.668
1.05HisLys: 1.05 ± 0.538
1.05HisLeu: 1.05 ± 0.668
0.525HisMet: 0.525 ± 0.668
0.525HisAsn: 0.525 ± 0.334
0.525HisPro: 0.525 ± 0.668
1.05HisGln: 1.05 ± 0.35
0.0HisArg: 0.0 ± 0.0
0.525HisSer: 0.525 ± 0.397
3.151HisThr: 3.151 ± 2.332
2.101HisVal: 2.101 ± 0.803
0.0HisTrp: 0.0 ± 0.0
2.626HisTyr: 2.626 ± 0.869
0.0HisXaa: 0.0 ± 0.0
Ile
4.727IleAla: 4.727 ± 2.332
1.576IleCys: 1.576 ± 0.557
0.525IleAsp: 0.525 ± 0.668
2.101IleGlu: 2.101 ± 1.008
0.0IlePhe: 0.0 ± 0.0
1.576IleGly: 1.576 ± 0.671
1.05IleHis: 1.05 ± 0.653
2.626IleIle: 2.626 ± 0.215
2.101IleLys: 2.101 ± 0.701
3.676IleLeu: 3.676 ± 0.471
0.0IleMet: 0.0 ± 0.0
1.05IleAsn: 1.05 ± 0.35
2.101IlePro: 2.101 ± 1.008
1.576IleGln: 1.576 ± 0.351
0.525IleArg: 0.525 ± 0.397
1.576IleSer: 1.576 ± 0.557
3.151IleThr: 3.151 ± 1.478
5.777IleVal: 5.777 ± 0.547
0.525IleTrp: 0.525 ± 0.334
3.151IleTyr: 3.151 ± 0.206
0.0IleXaa: 0.0 ± 0.0
Lys
2.626LysAla: 2.626 ± 0.869
2.626LysCys: 2.626 ± 1.164
1.576LysAsp: 1.576 ± 1.192
3.676LysGlu: 3.676 ± 0.471
1.576LysPhe: 1.576 ± 0.85
3.676LysGly: 3.676 ± 1.398
2.101LysHis: 2.101 ± 1.307
3.676LysIle: 3.676 ± 0.8
4.727LysLys: 4.727 ± 1.17
4.202LysLeu: 4.202 ± 1.137
2.626LysMet: 2.626 ± 0.379
2.101LysAsn: 2.101 ± 1.076
3.676LysPro: 3.676 ± 0.512
1.576LysGln: 1.576 ± 0.351
3.676LysArg: 3.676 ± 0.471
1.576LysSer: 1.576 ± 0.351
4.727LysThr: 4.727 ± 0.764
4.727LysVal: 4.727 ± 0.146
1.05LysTrp: 1.05 ± 0.35
1.05LysTyr: 1.05 ± 0.653
0.0LysXaa: 0.0 ± 0.0
Leu
5.777LeuAla: 5.777 ± 1.135
2.101LeuCys: 2.101 ± 0.803
3.676LeuAsp: 3.676 ± 1.354
6.303LeuGlu: 6.303 ± 1.209
2.101LeuPhe: 2.101 ± 0.523
2.626LeuGly: 2.626 ± 0.817
2.101LeuHis: 2.101 ± 0.701
4.727LeuIle: 4.727 ± 0.146
4.727LeuLys: 4.727 ± 0.589
6.828LeuLeu: 6.828 ± 2.055
3.151LeuMet: 3.151 ± 0.743
4.202LeuAsn: 4.202 ± 0.838
5.777LeuPro: 5.777 ± 1.971
3.151LeuGln: 3.151 ± 1.233
3.676LeuArg: 3.676 ± 2.219
5.252LeuSer: 5.252 ± 1.738
5.777LeuThr: 5.777 ± 2.257
4.202LeuVal: 4.202 ± 1.402
2.101LeuTrp: 2.101 ± 0.523
1.576LeuTyr: 1.576 ± 0.597
0.0LeuXaa: 0.0 ± 0.0
Met
1.576MetAla: 1.576 ± 2.004
0.0MetCys: 0.0 ± 0.0
2.101MetAsp: 2.101 ± 1.156
1.576MetGlu: 1.576 ± 0.671
2.626MetPhe: 2.626 ± 1.086
1.576MetGly: 1.576 ± 0.557
1.05MetHis: 1.05 ± 0.668
1.576MetIle: 1.576 ± 0.597
1.576MetLys: 1.576 ± 0.351
2.626MetLeu: 2.626 ± 0.431
0.525MetMet: 0.525 ± 0.334
1.576MetAsn: 1.576 ± 0.557
1.576MetPro: 1.576 ± 0.671
0.0MetGln: 0.0 ± 0.0
1.05MetArg: 1.05 ± 0.35
3.151MetSer: 3.151 ± 0.206
2.626MetThr: 2.626 ± 0.431
4.727MetVal: 4.727 ± 1.729
0.525MetTrp: 0.525 ± 0.668
0.525MetTyr: 0.525 ± 0.397
0.0MetXaa: 0.0 ± 0.0
Asn
3.676AsnAla: 3.676 ± 0.464
4.202AsnCys: 4.202 ± 1.273
2.101AsnAsp: 2.101 ± 0.803
4.727AsnGlu: 4.727 ± 1.227
0.0AsnPhe: 0.0 ± 0.0
1.576AsnGly: 1.576 ± 0.557
0.525AsnHis: 0.525 ± 0.668
1.05AsnIle: 1.05 ± 0.653
2.626AsnLys: 2.626 ± 0.817
1.576AsnLeu: 1.576 ± 0.671
3.151AsnMet: 3.151 ± 1.051
2.101AsnAsn: 2.101 ± 0.701
3.676AsnPro: 3.676 ± 1.372
2.626AsnGln: 2.626 ± 0.869
3.151AsnArg: 3.151 ± 0.206
2.626AsnSer: 2.626 ± 1.432
3.151AsnThr: 3.151 ± 0.206
3.151AsnVal: 3.151 ± 1.478
1.05AsnTrp: 1.05 ± 0.35
1.576AsnTyr: 1.576 ± 1.192
0.0AsnXaa: 0.0 ± 0.0
Pro
4.727ProAla: 4.727 ± 0.764
1.05ProCys: 1.05 ± 0.653
3.676ProAsp: 3.676 ± 0.512
3.151ProGlu: 3.151 ± 1.193
1.05ProPhe: 1.05 ± 0.668
6.303ProGly: 6.303 ± 0.879
1.05ProHis: 1.05 ± 0.668
2.101ProIle: 2.101 ± 0.701
4.202ProLys: 4.202 ± 0.466
5.777ProLeu: 5.777 ± 0.816
1.05ProMet: 1.05 ± 0.35
3.151ProAsn: 3.151 ± 0.604
3.676ProPro: 3.676 ± 0.464
2.101ProGln: 2.101 ± 1.59
2.626ProArg: 2.626 ± 0.994
0.525ProSer: 0.525 ± 0.668
6.303ProThr: 6.303 ± 1.287
4.727ProVal: 4.727 ± 0.793
1.576ProTrp: 1.576 ± 0.671
0.525ProTyr: 0.525 ± 0.334
0.0ProXaa: 0.0 ± 0.0
Gln
3.151GlnAla: 3.151 ± 1.115
0.525GlnCys: 0.525 ± 0.668
2.101GlnAsp: 2.101 ± 1.045
0.525GlnGlu: 0.525 ± 0.397
2.626GlnPhe: 2.626 ± 0.215
2.626GlnGly: 2.626 ± 0.994
0.0GlnHis: 0.0 ± 0.0
1.05GlnIle: 1.05 ± 0.653
4.727GlnLys: 4.727 ± 1.794
3.151GlnLeu: 3.151 ± 0.206
2.101GlnMet: 2.101 ± 1.045
2.101GlnAsn: 2.101 ± 0.523
2.626GlnPro: 2.626 ± 0.994
2.626GlnGln: 2.626 ± 1.432
2.101GlnArg: 2.101 ± 0.849
1.05GlnSer: 1.05 ± 0.35
4.727GlnThr: 4.727 ± 0.793
1.576GlnVal: 1.576 ± 1.002
0.0GlnTrp: 0.0 ± 0.0
1.576GlnTyr: 1.576 ± 2.004
0.0GlnXaa: 0.0 ± 0.0
Arg
3.676ArgAla: 3.676 ± 0.797
0.0ArgCys: 0.0 ± 0.0
4.727ArgAsp: 4.727 ± 1.227
2.626ArgGlu: 2.626 ± 0.215
4.202ArgPhe: 4.202 ± 0.839
5.252ArgGly: 5.252 ± 0.882
0.525ArgHis: 0.525 ± 0.334
2.626ArgIle: 2.626 ± 0.817
2.626ArgLys: 2.626 ± 1.464
5.252ArgLeu: 5.252 ± 1.962
1.576ArgMet: 1.576 ± 0.597
2.626ArgAsn: 2.626 ± 0.817
1.576ArgPro: 1.576 ± 0.671
0.0ArgGln: 0.0 ± 0.0
4.202ArgArg: 4.202 ± 1.397
2.101ArgSer: 2.101 ± 0.523
2.626ArgThr: 2.626 ± 1.464
2.626ArgVal: 2.626 ± 0.869
1.05ArgTrp: 1.05 ± 0.538
2.626ArgTyr: 2.626 ± 1.674
0.0ArgXaa: 0.0 ± 0.0
Ser
5.252SerAla: 5.252 ± 0.805
0.525SerCys: 0.525 ± 0.397
3.676SerAsp: 3.676 ± 1.0
2.626SerGlu: 2.626 ± 1.689
0.525SerPhe: 0.525 ± 0.668
3.676SerGly: 3.676 ± 1.0
2.101SerHis: 2.101 ± 1.076
1.576SerIle: 1.576 ± 0.85
0.525SerLys: 0.525 ± 0.397
5.777SerLeu: 5.777 ± 2.016
1.05SerMet: 1.05 ± 0.668
1.05SerAsn: 1.05 ± 0.795
3.676SerPro: 3.676 ± 1.0
1.05SerGln: 1.05 ± 0.538
3.151SerArg: 3.151 ± 1.115
4.202SerSer: 4.202 ± 3.179
3.151SerThr: 3.151 ± 0.206
3.151SerVal: 3.151 ± 0.737
0.525SerTrp: 0.525 ± 0.397
2.626SerTyr: 2.626 ± 0.215
0.0SerXaa: 0.0 ± 0.0
Thr
7.878ThrAla: 7.878 ± 2.607
0.525ThrCys: 0.525 ± 0.334
2.626ThrAsp: 2.626 ± 1.164
7.353ThrGlu: 7.353 ± 1.802
1.05ThrPhe: 1.05 ± 0.538
4.727ThrGly: 4.727 ± 0.146
1.576ThrHis: 1.576 ± 1.26
2.101ThrIle: 2.101 ± 1.008
5.777ThrLys: 5.777 ± 1.813
4.727ThrLeu: 4.727 ± 1.227
0.525ThrMet: 0.525 ± 0.668
2.626ThrAsn: 2.626 ± 1.164
7.878ThrPro: 7.878 ± 0.945
2.101ThrGln: 2.101 ± 0.701
4.202ThrArg: 4.202 ± 2.016
3.676ThrSer: 3.676 ± 0.464
8.403ThrThr: 8.403 ± 2.155
6.828ThrVal: 6.828 ± 0.635
0.525ThrTrp: 0.525 ± 0.397
2.101ThrTyr: 2.101 ± 0.208
0.0ThrXaa: 0.0 ± 0.0
Val
5.777ValAla: 5.777 ± 2.245
1.05ValCys: 1.05 ± 0.35
2.101ValAsp: 2.101 ± 0.208
3.151ValGlu: 3.151 ± 1.478
2.626ValPhe: 2.626 ± 0.817
7.878ValGly: 7.878 ± 0.651
2.101ValHis: 2.101 ± 0.803
1.576ValIle: 1.576 ± 0.597
3.676ValLys: 3.676 ± 0.471
6.303ValLeu: 6.303 ± 2.102
3.676ValMet: 3.676 ± 1.431
4.727ValAsn: 4.727 ± 0.764
1.05ValPro: 1.05 ± 0.668
2.626ValGln: 2.626 ± 0.817
3.676ValArg: 3.676 ± 0.471
4.727ValSer: 4.727 ± 0.726
3.151ValThr: 3.151 ± 0.604
4.727ValVal: 4.727 ± 0.589
1.576ValTrp: 1.576 ± 1.192
4.727ValTyr: 4.727 ± 0.793
0.0ValXaa: 0.0 ± 0.0
Trp
0.525TrpAla: 0.525 ± 0.334
0.0TrpCys: 0.0 ± 0.0
1.05TrpAsp: 1.05 ± 0.795
1.05TrpGlu: 1.05 ± 0.668
0.0TrpPhe: 0.0 ± 0.0
1.05TrpGly: 1.05 ± 0.653
2.101TrpHis: 2.101 ± 0.701
1.05TrpIle: 1.05 ± 0.538
1.576TrpLys: 1.576 ± 0.671
0.525TrpLeu: 0.525 ± 0.668
0.0TrpMet: 0.0 ± 0.0
1.05TrpAsn: 1.05 ± 0.795
0.0TrpPro: 0.0 ± 0.0
1.05TrpGln: 1.05 ± 0.35
0.0TrpArg: 0.0 ± 0.0
1.05TrpSer: 1.05 ± 0.795
1.05TrpThr: 1.05 ± 1.336
1.05TrpVal: 1.05 ± 0.653
0.525TrpTrp: 0.525 ± 0.334
2.101TrpTyr: 2.101 ± 0.803
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.576TyrAla: 1.576 ± 0.351
1.05TyrCys: 1.05 ± 0.668
2.101TyrAsp: 2.101 ± 1.076
1.576TyrGlu: 1.576 ± 0.597
0.525TyrPhe: 0.525 ± 0.397
3.151TyrGly: 3.151 ± 1.376
1.05TyrHis: 1.05 ± 0.795
0.525TyrIle: 0.525 ± 0.334
1.05TyrLys: 1.05 ± 1.336
4.202TyrLeu: 4.202 ± 0.416
1.05TyrMet: 1.05 ± 1.336
3.151TyrAsn: 3.151 ± 0.604
3.676TyrPro: 3.676 ± 0.8
1.576TyrGln: 1.576 ± 0.671
4.727TyrArg: 4.727 ± 1.294
2.626TyrSer: 2.626 ± 0.994
2.626TyrThr: 2.626 ± 0.994
2.101TyrVal: 2.101 ± 0.208
0.0TyrTrp: 0.0 ± 0.0
1.05TyrTyr: 1.05 ± 1.336
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1905 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski