Amino acid dipepetide frequency for Torque teno virus 15

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.396AlaAla: 4.396 ± 0.98
1.099AlaCys: 1.099 ± 2.6
5.495AlaAsp: 5.495 ± 3.58
1.099AlaGlu: 1.099 ± 2.6
0.0AlaPhe: 0.0 ± 0.0
3.297AlaGly: 3.297 ± 1.52
0.0AlaHis: 0.0 ± 0.0
1.099AlaIle: 1.099 ± 0.54
4.396AlaLys: 4.396 ± 0.98
3.297AlaLeu: 3.297 ± 4.66
0.0AlaMet: 0.0 ± 0.0
5.495AlaAsn: 5.495 ± 0.44
2.198AlaPro: 2.198 ± 5.2
2.198AlaGln: 2.198 ± 1.08
2.198AlaArg: 2.198 ± 1.08
1.099AlaSer: 1.099 ± 0.54
3.297AlaThr: 3.297 ± 1.52
1.099AlaVal: 1.099 ± 2.6
2.198AlaTrp: 2.198 ± 1.08
2.198AlaTyr: 2.198 ± 1.08
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.099CysAsp: 1.099 ± 0.54
1.099CysGlu: 1.099 ± 2.6
1.099CysPhe: 1.099 ± 2.6
2.198CysGly: 2.198 ± 2.06
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
3.297CysLys: 3.297 ± 1.62
2.198CysLeu: 2.198 ± 2.06
0.0CysMet: 0.0 ± 0.0
1.099CysAsn: 1.099 ± 2.6
1.099CysPro: 1.099 ± 0.54
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.099CysSer: 1.099 ± 0.54
2.198CysThr: 2.198 ± 1.08
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.099AspAla: 1.099 ± 2.6
0.0AspCys: 0.0 ± 0.0
1.099AspAsp: 1.099 ± 0.54
3.297AspGlu: 3.297 ± 1.52
3.297AspPhe: 3.297 ± 1.52
2.198AspGly: 2.198 ± 2.06
2.198AspHis: 2.198 ± 1.08
2.198AspIle: 2.198 ± 1.08
4.396AspLys: 4.396 ± 2.16
6.593AspLeu: 6.593 ± 0.1
1.099AspMet: 1.099 ± 0.54
1.099AspAsn: 1.099 ± 0.54
1.099AspPro: 1.099 ± 2.6
3.297AspGln: 3.297 ± 1.62
1.099AspArg: 1.099 ± 0.54
6.593AspSer: 6.593 ± 3.24
3.297AspThr: 3.297 ± 1.62
4.396AspVal: 4.396 ± 2.16
0.0AspTrp: 0.0 ± 0.0
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.198GluAla: 2.198 ± 1.08
0.0GluCys: 0.0 ± 0.0
4.396GluAsp: 4.396 ± 7.26
3.297GluGlu: 3.297 ± 4.66
1.099GluPhe: 1.099 ± 0.54
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
1.099GluIle: 1.099 ± 0.54
6.593GluLys: 6.593 ± 3.24
2.198GluLeu: 2.198 ± 1.08
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
0.0GluPro: 0.0 ± 0.0
5.495GluGln: 5.495 ± 3.58
4.396GluArg: 4.396 ± 4.12
3.297GluSer: 3.297 ± 1.52
2.198GluThr: 2.198 ± 1.08
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
2.198GluTyr: 2.198 ± 1.08
0.0GluXaa: 0.0 ± 0.0
Phe
3.297PheAla: 3.297 ± 1.62
2.198PheCys: 2.198 ± 2.06
2.198PheAsp: 2.198 ± 2.06
4.396PheGlu: 4.396 ± 0.98
0.0PhePhe: 0.0 ± 0.0
4.396PheGly: 4.396 ± 2.16
1.099PheHis: 1.099 ± 0.54
2.198PheIle: 2.198 ± 1.08
2.198PheLys: 2.198 ± 1.08
1.099PheLeu: 1.099 ± 0.54
0.0PheMet: 0.0 ± 0.0
6.593PheAsn: 6.593 ± 3.04
2.198PhePro: 2.198 ± 1.08
4.396PheGln: 4.396 ± 2.16
3.297PheArg: 3.297 ± 1.62
3.297PheSer: 3.297 ± 1.52
2.198PheThr: 2.198 ± 1.08
3.297PheVal: 3.297 ± 1.62
0.0PheTrp: 0.0 ± 0.0
2.198PheTyr: 2.198 ± 1.08
0.0PheXaa: 0.0 ± 0.0
Gly
2.198GlyAla: 2.198 ± 2.06
2.198GlyCys: 2.198 ± 2.06
2.198GlyAsp: 2.198 ± 1.08
3.297GlyGlu: 3.297 ± 7.8
1.099GlyPhe: 1.099 ± 0.54
7.692GlyGly: 7.692 ± 5.64
1.099GlyHis: 1.099 ± 0.54
1.099GlyIle: 1.099 ± 0.54
1.099GlyLys: 1.099 ± 0.54
4.396GlyLeu: 4.396 ± 2.16
3.297GlyMet: 3.297 ± 1.62
2.198GlyAsn: 2.198 ± 1.08
5.495GlyPro: 5.495 ± 0.44
1.099GlyGln: 1.099 ± 0.54
3.297GlyArg: 3.297 ± 1.52
3.297GlySer: 3.297 ± 1.52
0.0GlyThr: 0.0 ± 0.0
0.0GlyVal: 0.0 ± 0.0
3.297GlyTrp: 3.297 ± 1.62
5.495GlyTyr: 5.495 ± 2.7
0.0GlyXaa: 0.0 ± 0.0
His
2.198HisAla: 2.198 ± 2.06
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.099HisGlu: 1.099 ± 0.54
3.297HisPhe: 3.297 ± 4.66
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.099HisIle: 1.099 ± 0.54
0.0HisLys: 0.0 ± 0.0
5.495HisLeu: 5.495 ± 2.7
1.099HisMet: 1.099 ± 0.54
0.0HisAsn: 0.0 ± 0.0
3.297HisPro: 3.297 ± 1.62
2.198HisGln: 2.198 ± 1.08
0.0HisArg: 0.0 ± 0.0
2.198HisSer: 2.198 ± 1.08
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
1.099HisTrp: 1.099 ± 0.54
1.099HisTyr: 1.099 ± 0.54
0.0HisXaa: 0.0 ± 0.0
Ile
1.099IleAla: 1.099 ± 2.6
2.198IleCys: 2.198 ± 2.06
1.099IleAsp: 1.099 ± 0.54
0.0IleGlu: 0.0 ± 0.0
2.198IlePhe: 2.198 ± 1.08
2.198IleGly: 2.198 ± 1.08
1.099IleHis: 1.099 ± 2.6
1.099IleIle: 1.099 ± 0.54
1.099IleLys: 1.099 ± 0.54
2.198IleLeu: 2.198 ± 1.08
1.099IleMet: 1.099 ± 0.54
4.396IleAsn: 4.396 ± 2.16
4.396IlePro: 4.396 ± 2.16
1.099IleGln: 1.099 ± 0.54
3.297IleArg: 3.297 ± 1.62
1.099IleSer: 1.099 ± 0.54
1.099IleThr: 1.099 ± 2.6
2.198IleVal: 2.198 ± 1.08
0.0IleTrp: 0.0 ± 0.0
2.198IleTyr: 2.198 ± 1.08
0.0IleXaa: 0.0 ± 0.0
Lys
1.099LysAla: 1.099 ± 0.54
1.099LysCys: 1.099 ± 0.54
2.198LysAsp: 2.198 ± 1.08
2.198LysGlu: 2.198 ± 1.08
4.396LysPhe: 4.396 ± 2.16
3.297LysGly: 3.297 ± 1.62
1.099LysHis: 1.099 ± 0.54
4.396LysIle: 4.396 ± 0.98
6.593LysLys: 6.593 ± 0.1
5.495LysLeu: 5.495 ± 0.44
0.0LysMet: 0.0 ± 0.0
3.297LysAsn: 3.297 ± 1.52
2.198LysPro: 2.198 ± 1.08
3.297LysGln: 3.297 ± 1.62
7.692LysArg: 7.692 ± 0.64
0.0LysSer: 0.0 ± 0.0
3.297LysThr: 3.297 ± 1.62
1.099LysVal: 1.099 ± 0.54
2.198LysTrp: 2.198 ± 1.08
1.099LysTyr: 1.099 ± 0.54
0.0LysXaa: 0.0 ± 0.0
Leu
3.297LeuAla: 3.297 ± 1.52
1.099LeuCys: 1.099 ± 0.54
1.099LeuAsp: 1.099 ± 0.54
0.0LeuGlu: 0.0 ± 0.0
6.593LeuPhe: 6.593 ± 3.24
3.297LeuGly: 3.297 ± 1.62
1.099LeuHis: 1.099 ± 0.54
3.297LeuIle: 3.297 ± 1.62
4.396LeuLys: 4.396 ± 2.16
3.297LeuLeu: 3.297 ± 4.66
2.198LeuMet: 2.198 ± 2.06
4.396LeuAsn: 4.396 ± 0.98
5.495LeuPro: 5.495 ± 6.72
8.791LeuGln: 8.791 ± 1.18
9.89LeuArg: 9.89 ± 1.42
2.198LeuSer: 2.198 ± 1.08
5.495LeuThr: 5.495 ± 2.7
5.495LeuVal: 5.495 ± 2.7
1.099LeuTrp: 1.099 ± 0.54
2.198LeuTyr: 2.198 ± 1.08
0.0LeuXaa: 0.0 ± 0.0
Met
2.198MetAla: 2.198 ± 2.06
1.099MetCys: 1.099 ± 0.54
1.099MetAsp: 1.099 ± 0.54
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
2.198MetGly: 2.198 ± 1.08
2.198MetHis: 2.198 ± 2.06
1.099MetIle: 1.099 ± 0.54
1.099MetLys: 1.099 ± 0.54
2.198MetLeu: 2.198 ± 1.08
0.0MetMet: 0.0 ± 0.0
1.099MetAsn: 1.099 ± 0.54
0.0MetPro: 0.0 ± 0.0
1.099MetGln: 1.099 ± 0.54
0.0MetArg: 0.0 ± 0.0
2.198MetSer: 2.198 ± 2.06
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
2.198MetTyr: 2.198 ± 1.08
0.0MetXaa: 0.0 ± 0.0
Asn
3.297AsnAla: 3.297 ± 1.52
0.0AsnCys: 0.0 ± 0.0
3.297AsnAsp: 3.297 ± 1.62
0.0AsnGlu: 0.0 ± 0.0
2.198AsnPhe: 2.198 ± 1.08
2.198AsnGly: 2.198 ± 1.08
1.099AsnHis: 1.099 ± 0.54
3.297AsnIle: 3.297 ± 1.52
0.0AsnLys: 0.0 ± 0.0
3.297AsnLeu: 3.297 ± 1.62
1.099AsnMet: 1.099 ± 0.449
3.297AsnAsn: 3.297 ± 4.66
9.89AsnPro: 9.89 ± 1.42
2.198AsnGln: 2.198 ± 5.2
3.297AsnArg: 3.297 ± 1.62
2.198AsnSer: 2.198 ± 1.08
4.396AsnThr: 4.396 ± 2.16
1.099AsnVal: 1.099 ± 2.6
2.198AsnTrp: 2.198 ± 2.06
3.297AsnTyr: 3.297 ± 1.52
0.0AsnXaa: 0.0 ± 0.0
Pro
4.396ProAla: 4.396 ± 7.26
2.198ProCys: 2.198 ± 1.08
3.297ProAsp: 3.297 ± 1.62
2.198ProGlu: 2.198 ± 1.08
4.396ProPhe: 4.396 ± 2.16
2.198ProGly: 2.198 ± 2.06
1.099ProHis: 1.099 ± 0.54
3.297ProIle: 3.297 ± 1.52
3.297ProLys: 3.297 ± 1.62
7.692ProLeu: 7.692 ± 2.5
2.198ProMet: 2.198 ± 1.08
3.297ProAsn: 3.297 ± 1.62
10.989ProPro: 10.989 ± 10.3
6.593ProGln: 6.593 ± 3.04
5.495ProArg: 5.495 ± 2.7
4.396ProSer: 4.396 ± 4.12
4.396ProThr: 4.396 ± 4.12
4.396ProVal: 4.396 ± 4.12
1.099ProTrp: 1.099 ± 2.6
1.099ProTyr: 1.099 ± 0.54
0.0ProXaa: 0.0 ± 0.0
Gln
4.396GlnAla: 4.396 ± 0.98
1.099GlnCys: 1.099 ± 0.54
3.297GlnAsp: 3.297 ± 1.62
2.198GlnGlu: 2.198 ± 1.08
2.198GlnPhe: 2.198 ± 1.08
0.0GlnGly: 0.0 ± 0.0
1.099GlnHis: 1.099 ± 0.54
3.297GlnIle: 3.297 ± 1.62
4.396GlnLys: 4.396 ± 2.16
7.692GlnLeu: 7.692 ± 3.78
0.0GlnMet: 0.0 ± 1.339
3.297GlnAsn: 3.297 ± 4.66
5.495GlnPro: 5.495 ± 0.44
5.495GlnGln: 5.495 ± 2.7
5.495GlnArg: 5.495 ± 3.58
0.0GlnSer: 0.0 ± 0.0
5.495GlnThr: 5.495 ± 0.44
4.396GlnVal: 4.396 ± 2.16
2.198GlnTrp: 2.198 ± 1.08
4.396GlnTyr: 4.396 ± 2.16
0.0GlnXaa: 0.0 ± 0.0
Arg
3.297ArgAla: 3.297 ± 1.52
1.099ArgCys: 1.099 ± 0.54
4.396ArgAsp: 4.396 ± 2.16
2.198ArgGlu: 2.198 ± 1.08
5.495ArgPhe: 5.495 ± 0.44
5.495ArgGly: 5.495 ± 0.44
1.099ArgHis: 1.099 ± 0.54
0.0ArgIle: 0.0 ± 0.0
6.593ArgLys: 6.593 ± 3.04
7.692ArgLeu: 7.692 ± 0.64
1.099ArgMet: 1.099 ± 0.54
1.099ArgAsn: 1.099 ± 2.6
5.495ArgPro: 5.495 ± 6.72
3.297ArgGln: 3.297 ± 1.62
28.571ArgArg: 28.571 ± 14.041
3.297ArgSer: 3.297 ± 4.66
4.396ArgThr: 4.396 ± 0.98
3.297ArgVal: 3.297 ± 1.62
4.396ArgTrp: 4.396 ± 2.16
3.297ArgTyr: 3.297 ± 1.62
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
1.099SerCys: 1.099 ± 2.6
2.198SerAsp: 2.198 ± 1.08
2.198SerGlu: 2.198 ± 1.08
4.396SerPhe: 4.396 ± 2.16
5.495SerGly: 5.495 ± 3.58
1.099SerHis: 1.099 ± 2.6
1.099SerIle: 1.099 ± 0.54
1.099SerLys: 1.099 ± 2.6
1.099SerLeu: 1.099 ± 0.54
1.099SerMet: 1.099 ± 0.54
3.297SerAsn: 3.297 ± 1.62
3.297SerPro: 3.297 ± 1.62
5.495SerGln: 5.495 ± 0.44
3.297SerArg: 3.297 ± 4.66
7.692SerSer: 7.692 ± 0.64
8.791SerThr: 8.791 ± 4.32
0.0SerVal: 0.0 ± 0.0
3.297SerTrp: 3.297 ± 1.52
2.198SerTyr: 2.198 ± 1.08
0.0SerXaa: 0.0 ± 0.0
Thr
4.396ThrAla: 4.396 ± 0.98
0.0ThrCys: 0.0 ± 0.0
3.297ThrAsp: 3.297 ± 1.62
5.495ThrGlu: 5.495 ± 2.7
5.495ThrPhe: 5.495 ± 2.7
1.099ThrGly: 1.099 ± 0.54
4.396ThrHis: 4.396 ± 2.16
2.198ThrIle: 2.198 ± 1.08
2.198ThrLys: 2.198 ± 1.08
1.099ThrLeu: 1.099 ± 0.54
2.198ThrMet: 2.198 ± 2.06
2.198ThrAsn: 2.198 ± 1.08
2.198ThrPro: 2.198 ± 1.08
6.593ThrGln: 6.593 ± 3.24
5.495ThrArg: 5.495 ± 6.72
4.396ThrSer: 4.396 ± 2.16
4.396ThrThr: 4.396 ± 0.98
6.593ThrVal: 6.593 ± 0.1
1.099ThrTrp: 1.099 ± 0.54
5.495ThrTyr: 5.495 ± 2.7
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
4.396ValGlu: 4.396 ± 0.98
1.099ValPhe: 1.099 ± 0.54
2.198ValGly: 2.198 ± 2.06
1.099ValHis: 1.099 ± 0.54
2.198ValIle: 2.198 ± 2.06
1.099ValLys: 1.099 ± 0.54
4.396ValLeu: 4.396 ± 2.16
1.099ValMet: 1.099 ± 0.54
0.0ValAsn: 0.0 ± 0.0
8.791ValPro: 8.791 ± 1.96
3.297ValGln: 3.297 ± 1.62
3.297ValArg: 3.297 ± 1.62
1.099ValSer: 1.099 ± 0.54
5.495ValThr: 5.495 ± 2.7
2.198ValVal: 2.198 ± 1.08
1.099ValTrp: 1.099 ± 0.54
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.099TrpAla: 1.099 ± 0.54
0.0TrpCys: 0.0 ± 0.0
1.099TrpAsp: 1.099 ± 0.54
0.0TrpGlu: 0.0 ± 0.0
2.198TrpPhe: 2.198 ± 2.06
2.198TrpGly: 2.198 ± 1.08
1.099TrpHis: 1.099 ± 0.54
0.0TrpIle: 0.0 ± 0.0
1.099TrpLys: 1.099 ± 0.54
2.198TrpLeu: 2.198 ± 1.08
0.0TrpMet: 0.0 ± 0.0
1.099TrpAsn: 1.099 ± 0.54
1.099TrpPro: 1.099 ± 2.6
0.0TrpGln: 0.0 ± 0.0
3.297TrpArg: 3.297 ± 1.62
3.297TrpSer: 3.297 ± 1.52
3.297TrpThr: 3.297 ± 1.62
0.0TrpVal: 0.0 ± 0.0
1.099TrpTrp: 1.099 ± 0.54
4.396TrpTyr: 4.396 ± 2.16
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.198TyrAla: 2.198 ± 1.08
0.0TyrCys: 0.0 ± 0.0
5.495TyrAsp: 5.495 ± 2.7
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
2.198TyrGly: 2.198 ± 1.08
2.198TyrHis: 2.198 ± 1.08
1.099TyrIle: 1.099 ± 0.54
1.099TyrLys: 1.099 ± 0.54
1.099TyrLeu: 1.099 ± 2.6
1.099TyrMet: 1.099 ± 0.54
4.396TyrAsn: 4.396 ± 2.16
3.297TyrPro: 3.297 ± 1.62
1.099TyrGln: 1.099 ± 0.54
2.198TyrArg: 2.198 ± 1.08
5.495TyrSer: 5.495 ± 2.7
6.593TyrThr: 6.593 ± 3.24
3.297TyrVal: 3.297 ± 1.62
2.198TyrTrp: 2.198 ± 1.08
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (911 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski