Human papillomavirus 73

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 11

Average proteome isoelectric point is 6.72

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 8 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q82009|Q82009_HPV73 Minor capsid protein L2 OS=Human papillomavirus 73 OX=51033 GN=L2 PE=3 SV=1
MM1 pKa = 7.4HH2 pKa = 7.31GKK4 pKa = 8.13KK5 pKa = 6.97TTLQDD10 pKa = 2.74ITLDD14 pKa = 3.83LKK16 pKa = 10.13PTTEE20 pKa = 4.3IDD22 pKa = 3.57LTCYY26 pKa = 10.45EE27 pKa = 4.53SLDD30 pKa = 3.63NSEE33 pKa = 5.89DD34 pKa = 3.66EE35 pKa = 5.64DD36 pKa = 3.99EE37 pKa = 4.71TDD39 pKa = 3.39SHH41 pKa = 7.9LDD43 pKa = 3.2RR44 pKa = 11.84QAEE47 pKa = 4.21RR48 pKa = 11.84EE49 pKa = 4.34CYY51 pKa = 10.18RR52 pKa = 11.84IVTDD56 pKa = 4.27CTKK59 pKa = 10.51CQCTVCLAIEE69 pKa = 4.29SNKK72 pKa = 10.18ADD74 pKa = 3.3LRR76 pKa = 11.84VIEE79 pKa = 4.33EE80 pKa = 4.59LLMGTLGIVCPNCSRR95 pKa = 11.84NLL97 pKa = 3.55

Molecular weight: 10.97 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0P0ELC3|A0A0P0ELC3_HPV73 Replication protein E1 OS=Human papillomavirus 73 OX=51033 GN=E1 PE=3 SV=1
YYY2 pKa = 10.19VLLYYY7 pKa = 9.74APVKKK12 pKa = 11.0YY13 pKa = 10.09FLKKK17 pKa = 10.77LTHHH21 pKa = 6.75TPQPPTPPPPAPTLTPVCHHH41 pKa = 6.7HH42 pKa = 6.84NGKKK46 pKa = 10.38DD47 pKa = 3.16VTRR50 pKa = 11.84TRR52 pKa = 11.84GPWSVCITYYY62 pKa = 9.91PPQSPVPSVLHHH74 pKa = 5.91MLRR77 pKa = 11.84Q

Molecular weight: 8.64 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

8

0

8

2375

74

650

296.9

33.41

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.547 ± 0.422

3.158 ± 0.906

5.853 ± 0.481

4.589 ± 0.641

3.747 ± 0.47

5.6 ± 0.575

2.4 ± 0.545

5.684 ± 0.637

5.6 ± 0.481

8.8 ± 0.705

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.811 ± 0.314

4.379 ± 0.589

6.316 ± 1.039

4.547 ± 0.282

4.547 ± 0.385

7.705 ± 0.822

8.589 ± 0.955

6.568 ± 0.59

1.516 ± 0.343

4.042 ± 0.299
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski