Amino acid dipepetide frequency for Capsaspora owczarzaki (strain ATCC 30864)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.014AlaAla: 20.014 ± 0.157	1.349AlaCys: 1.349 ± 0.025	5.338AlaAsp: 5.338 ± 0.03	5.659AlaGlu: 5.659 ± 0.051	3.543AlaPhe: 3.543 ± 0.031	6.921AlaGly: 6.921 ± 0.049	2.343AlaHis: 2.343 ± 0.025	4.473AlaIle: 4.473 ± 0.032	4.042AlaLys: 4.042 ± 0.036	10.087AlaLeu: 10.087 ± 0.065	2.283AlaMet: 2.283 ± 0.019	3.752AlaAsn: 3.752 ± 0.03	6.975AlaPro: 6.975 ± 0.061	4.823AlaGln: 4.823 ± 0.036	5.939AlaArg: 5.939 ± 0.046	12.803AlaSer: 12.803 ± 0.123	7.954AlaThr: 7.954 ± 0.046	7.256AlaVal: 7.256 ± 0.048	0.92AlaTrp: 0.92 ± 0.014	1.73AlaTyr: 1.73 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	1.222CysAla: 1.222 ± 0.028	0.329CysCys: 0.329 ± 0.009	0.753CysAsp: 0.753 ± 0.015	0.601CysGlu: 0.601 ± 0.012	0.567CysPhe: 0.567 ± 0.011	0.906CysGly: 0.906 ± 0.017	0.336CysHis: 0.336 ± 0.009	0.676CysIle: 0.676 ± 0.013	0.503CysLys: 0.503 ± 0.01	1.294CysLeu: 1.294 ± 0.018	0.307CysMet: 0.307 ± 0.007	0.568CysAsn: 0.568 ± 0.016	0.714CysPro: 0.714 ± 0.02	0.49CysGln: 0.49 ± 0.014	0.739CysArg: 0.739 ± 0.012	1.207CysSer: 1.207 ± 0.035	0.979CysThr: 0.979 ± 0.049	1.033CysVal: 1.033 ± 0.022	0.18CysTrp: 0.18 ± 0.005	0.342CysTyr: 0.342 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	6.399AspAla: 6.399 ± 0.04	0.662AspCys: 0.662 ± 0.014	5.335AspAsp: 5.335 ± 0.075	3.982AspGlu: 3.982 ± 0.04	1.958AspPhe: 1.958 ± 0.016	3.445AspGly: 3.445 ± 0.03	1.194AspHis: 1.194 ± 0.015	2.09AspIle: 2.09 ± 0.016	1.903AspLys: 1.903 ± 0.022	4.631AspLeu: 4.631 ± 0.028	1.14AspMet: 1.14 ± 0.014	1.824AspAsn: 1.824 ± 0.021	2.623AspPro: 2.623 ± 0.023	1.923AspGln: 1.923 ± 0.019	2.735AspArg: 2.735 ± 0.027	4.209AspSer: 4.209 ± 0.031	2.688AspThr: 2.688 ± 0.02	3.605AspVal: 3.605 ± 0.025	0.604AspTrp: 0.604 ± 0.012	1.166AspTyr: 1.166 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	5.45GluAla: 5.45 ± 0.051	0.677GluCys: 0.677 ± 0.011	3.088GluAsp: 3.088 ± 0.034	3.387GluGlu: 3.387 ± 0.036	1.834GluPhe: 1.834 ± 0.02	2.329GluGly: 2.329 ± 0.023	1.416GluHis: 1.416 ± 0.02	2.086GluIle: 2.086 ± 0.023	1.99GluLys: 1.99 ± 0.026	5.556GluLeu: 5.556 ± 0.039	1.176GluMet: 1.176 ± 0.014	1.663GluAsn: 1.663 ± 0.02	2.364GluPro: 2.364 ± 0.026	2.754GluGln: 2.754 ± 0.026	3.469GluArg: 3.469 ± 0.031	3.851GluSer: 3.851 ± 0.034	2.879GluThr: 2.879 ± 0.025	2.862GluVal: 2.862 ± 0.027	0.527GluTrp: 0.527 ± 0.01	1.177GluTyr: 1.177 ± 0.014	0.0GluXaa: 0.0 ± 0.0
Phe	3.75PheAla: 3.75 ± 0.029	0.597PheCys: 0.597 ± 0.011	2.293PheAsp: 2.293 ± 0.023	1.926PheGlu: 1.926 ± 0.02	1.476PhePhe: 1.476 ± 0.02	2.709PheGly: 2.709 ± 0.034	0.884PheHis: 0.884 ± 0.011	1.405PheIle: 1.405 ± 0.015	1.305PheLys: 1.305 ± 0.016	3.146PheLeu: 3.146 ± 0.026	0.745PheMet: 0.745 ± 0.011	1.332PheAsn: 1.332 ± 0.016	1.604PhePro: 1.604 ± 0.017	1.311PheGln: 1.311 ± 0.016	1.848PheArg: 1.848 ± 0.02	2.867PheSer: 2.867 ± 0.024	2.009PheThr: 2.009 ± 0.022	2.893PheVal: 2.893 ± 0.027	0.398PheTrp: 0.398 ± 0.008	0.886PheTyr: 0.886 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	6.592GlyAla: 6.592 ± 0.055	0.783GlyCys: 0.783 ± 0.017	3.278GlyAsp: 3.278 ± 0.027	2.537GlyGlu: 2.537 ± 0.021	2.216GlyPhe: 2.216 ± 0.025	4.958GlyGly: 4.958 ± 0.052	1.459GlyHis: 1.459 ± 0.02	2.384GlyIle: 2.384 ± 0.026	2.378GlyLys: 2.378 ± 0.029	5.355GlyLeu: 5.355 ± 0.044	1.31GlyMet: 1.31 ± 0.016	2.307GlyAsn: 2.307 ± 0.024	2.36GlyPro: 2.36 ± 0.021	2.19GlyGln: 2.19 ± 0.019	3.289GlyArg: 3.289 ± 0.03	5.994GlySer: 5.994 ± 0.046	3.614GlyThr: 3.614 ± 0.031	3.936GlyVal: 3.936 ± 0.031	0.677GlyTrp: 0.677 ± 0.011	1.39GlyTyr: 1.39 ± 0.02	0.0GlyXaa: 0.0 ± 0.0
His	2.597HisAla: 2.597 ± 0.025	0.37HisCys: 0.37 ± 0.007	1.348HisAsp: 1.348 ± 0.018	1.222HisGlu: 1.222 ± 0.015	0.939HisPhe: 0.939 ± 0.014	1.572HisGly: 1.572 ± 0.019	1.258HisHis: 1.258 ± 0.029	1.017HisIle: 1.017 ± 0.013	0.743HisLys: 0.743 ± 0.012	2.368HisLeu: 2.368 ± 0.021	0.472HisMet: 0.472 ± 0.009	0.837HisAsn: 0.837 ± 0.011	1.686HisPro: 1.686 ± 0.019	1.33HisGln: 1.33 ± 0.021	1.534HisArg: 1.534 ± 0.016	2.16HisSer: 2.16 ± 0.028	1.27HisThr: 1.27 ± 0.015	1.675HisVal: 1.675 ± 0.018	0.25HisTrp: 0.25 ± 0.007	0.597HisTyr: 0.597 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.766IleAla: 4.766 ± 0.036	0.586IleCys: 0.586 ± 0.01	2.376IleAsp: 2.376 ± 0.023	2.232IleGlu: 2.232 ± 0.021	1.366IlePhe: 1.366 ± 0.017	2.596IleGly: 2.596 ± 0.033	0.95IleHis: 0.95 ± 0.013	1.582IleIle: 1.582 ± 0.019	1.558IleLys: 1.558 ± 0.02	3.427IleLeu: 3.427 ± 0.026	0.752IleMet: 0.752 ± 0.011	1.394IleAsn: 1.394 ± 0.017	2.309IlePro: 2.309 ± 0.021	1.578IleGln: 1.578 ± 0.017	2.231IleArg: 2.231 ± 0.02	3.105IleSer: 3.105 ± 0.024	2.266IleThr: 2.266 ± 0.026	3.12IleVal: 3.12 ± 0.025	0.381IleTrp: 0.381 ± 0.008	0.888IleTyr: 0.888 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	3.672LysAla: 3.672 ± 0.039	0.46LysCys: 0.46 ± 0.01	1.84LysAsp: 1.84 ± 0.028	1.969LysGlu: 1.969 ± 0.024	1.298LysPhe: 1.298 ± 0.017	1.738LysGly: 1.738 ± 0.021	1.018LysHis: 1.018 ± 0.013	1.47LysIle: 1.47 ± 0.018	2.136LysLys: 2.136 ± 0.036	3.705LysLeu: 3.705 ± 0.03	0.788LysMet: 0.788 ± 0.014	1.275LysAsn: 1.275 ± 0.015	2.294LysPro: 2.294 ± 0.028	1.903LysGln: 1.903 ± 0.022	2.641LysArg: 2.641 ± 0.028	2.905LysSer: 2.905 ± 0.026	2.234LysThr: 2.234 ± 0.022	2.237LysVal: 2.237 ± 0.024	0.383LysTrp: 0.383 ± 0.008	0.876LysTyr: 0.876 ± 0.011	0.0LysXaa: 0.0 ± 0.0
Leu	10.066LeuAla: 10.066 ± 0.063	1.407LeuCys: 1.407 ± 0.018	5.187LeuAsp: 5.187 ± 0.028	4.959LeuGlu: 4.959 ± 0.037	3.479LeuPhe: 3.479 ± 0.026	5.107LeuGly: 5.107 ± 0.034	2.565LeuHis: 2.565 ± 0.026	3.361LeuIle: 3.361 ± 0.027	3.653LeuLys: 3.653 ± 0.03	9.897LeuLeu: 9.897 ± 0.065	1.758LeuMet: 1.758 ± 0.018	3.19LeuAsn: 3.19 ± 0.026	5.695LeuPro: 5.695 ± 0.041	4.78LeuGln: 4.78 ± 0.041	5.755LeuArg: 5.755 ± 0.041	7.852LeuSer: 7.852 ± 0.039	5.521LeuThr: 5.521 ± 0.04	6.547LeuVal: 6.547 ± 0.045	0.886LeuTrp: 0.886 ± 0.012	2.132LeuTyr: 2.132 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.082MetAla: 2.082 ± 0.018	0.279MetCys: 0.279 ± 0.006	1.136MetAsp: 1.136 ± 0.014	0.994MetGlu: 0.994 ± 0.012	0.736MetPhe: 0.736 ± 0.011	1.022MetGly: 1.022 ± 0.015	0.586MetHis: 0.586 ± 0.009	0.773MetIle: 0.773 ± 0.012	0.63MetLys: 0.63 ± 0.011	2.243MetLeu: 2.243 ± 0.022	0.572MetMet: 0.572 ± 0.01	0.685MetAsn: 0.685 ± 0.012	1.242MetPro: 1.242 ± 0.016	1.089MetGln: 1.089 ± 0.012	1.249MetArg: 1.249 ± 0.015	1.905MetSer: 1.905 ± 0.019	1.322MetThr: 1.322 ± 0.018	1.158MetVal: 1.158 ± 0.016	0.188MetTrp: 0.188 ± 0.005	0.505MetTyr: 0.505 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.989AsnAla: 3.989 ± 0.033	0.559AsnCys: 0.559 ± 0.014	1.886AsnAsp: 1.886 ± 0.017	1.751AsnGlu: 1.751 ± 0.019	1.205AsnPhe: 1.205 ± 0.018	2.373AsnGly: 2.373 ± 0.024	0.803AsnHis: 0.803 ± 0.012	1.462AsnIle: 1.462 ± 0.017	1.421AsnLys: 1.421 ± 0.018	2.994AsnLeu: 2.994 ± 0.023	0.735AsnMet: 0.735 ± 0.011	1.811AsnAsn: 1.811 ± 0.026	2.25AsnPro: 2.25 ± 0.021	1.564AsnGln: 1.564 ± 0.021	1.737AsnArg: 1.737 ± 0.018	2.922AsnSer: 2.922 ± 0.029	2.121AsnThr: 2.121 ± 0.026	2.386AsnVal: 2.386 ± 0.022	0.38AsnTrp: 0.38 ± 0.009	0.827AsnTyr: 0.827 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	7.836ProAla: 7.836 ± 0.063	0.547ProCys: 0.547 ± 0.012	2.528ProAsp: 2.528 ± 0.021	2.769ProGlu: 2.769 ± 0.025	1.986ProPhe: 1.986 ± 0.018	3.08ProGly: 3.08 ± 0.03	1.288ProHis: 1.288 ± 0.017	2.081ProIle: 2.081 ± 0.02	1.871ProLys: 1.871 ± 0.023	4.833ProLeu: 4.833 ± 0.036	1.129ProMet: 1.129 ± 0.015	1.926ProAsn: 1.926 ± 0.02	4.83ProPro: 4.83 ± 0.068	2.471ProGln: 2.471 ± 0.033	2.948ProArg: 2.948 ± 0.027	6.573ProSer: 6.573 ± 0.045	4.103ProThr: 4.103 ± 0.033	4.035ProVal: 4.035 ± 0.031	0.432ProTrp: 0.432 ± 0.011	1.057ProTyr: 1.057 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	4.742GlnAla: 4.742 ± 0.04	0.575GlnCys: 0.575 ± 0.021	1.823GlnAsp: 1.823 ± 0.02	2.055GlnGlu: 2.055 ± 0.024	1.544GlnPhe: 1.544 ± 0.018	1.891GlnGly: 1.891 ± 0.021	1.655GlnHis: 1.655 ± 0.024	1.791GlnIle: 1.791 ± 0.02	1.322GlnLys: 1.322 ± 0.017	5.083GlnLeu: 5.083 ± 0.04	0.914GlnMet: 0.914 ± 0.012	1.308GlnAsn: 1.308 ± 0.017	3.257GlnPro: 3.257 ± 0.034	6.413GlnGln: 6.413 ± 0.149	3.049GlnArg: 3.049 ± 0.028	3.645GlnSer: 3.645 ± 0.031	2.406GlnThr: 2.406 ± 0.02	2.573GlnVal: 2.573 ± 0.025	0.427GlnTrp: 0.427 ± 0.008	0.98GlnTyr: 0.98 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	5.652ArgAla: 5.652 ± 0.036	0.784ArgCys: 0.784 ± 0.015	2.973ArgAsp: 2.973 ± 0.03	3.032ArgGlu: 3.032 ± 0.031	2.179ArgPhe: 2.179 ± 0.022	3.025ArgGly: 3.025 ± 0.028	1.577ArgHis: 1.577 ± 0.019	2.49ArgIle: 2.49 ± 0.025	2.515ArgLys: 2.515 ± 0.024	5.775ArgLeu: 5.775 ± 0.04	1.282ArgMet: 1.282 ± 0.015	2.0ArgAsn: 2.0 ± 0.018	3.072ArgPro: 3.072 ± 0.029	2.869ArgGln: 2.869 ± 0.029	4.617ArgArg: 4.617 ± 0.043	4.781ArgSer: 4.781 ± 0.037	3.141ArgThr: 3.141 ± 0.024	3.758ArgVal: 3.758 ± 0.03	0.625ArgTrp: 0.625 ± 0.011	1.173ArgTyr: 1.173 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	11.467SerAla: 11.467 ± 0.084	1.12SerCys: 1.12 ± 0.034	4.609SerAsp: 4.609 ± 0.031	3.9SerGlu: 3.9 ± 0.031	3.043SerPhe: 3.043 ± 0.028	6.028SerGly: 6.028 ± 0.043	2.088SerHis: 2.088 ± 0.024	3.663SerIle: 3.663 ± 0.03	3.189SerLys: 3.189 ± 0.027	7.825SerLeu: 7.825 ± 0.041	1.781SerMet: 1.781 ± 0.021	3.472SerAsn: 3.472 ± 0.03	5.457SerPro: 5.457 ± 0.049	3.547SerGln: 3.547 ± 0.032	4.764SerArg: 4.764 ± 0.037	14.419SerSer: 14.419 ± 0.121	6.881SerThr: 6.881 ± 0.054	5.841SerVal: 5.841 ± 0.053	0.799SerTrp: 0.799 ± 0.013	1.587SerTyr: 1.587 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	7.446ThrAla: 7.446 ± 0.048	0.998ThrCys: 0.998 ± 0.041	2.761ThrAsp: 2.761 ± 0.023	2.624ThrGlu: 2.624 ± 0.021	2.179ThrPhe: 2.179 ± 0.023	3.731ThrGly: 3.731 ± 0.03	1.34ThrHis: 1.34 ± 0.016	2.637ThrIle: 2.637 ± 0.028	2.07ThrLys: 2.07 ± 0.018	5.988ThrLeu: 5.988 ± 0.04	1.154ThrMet: 1.154 ± 0.014	2.113ThrAsn: 2.113 ± 0.024	4.445ThrPro: 4.445 ± 0.046	2.227ThrGln: 2.227 ± 0.023	3.113ThrArg: 3.113 ± 0.024	6.381ThrSer: 6.381 ± 0.053	5.505ThrThr: 5.505 ± 0.049	4.073ThrVal: 4.073 ± 0.03	0.577ThrTrp: 0.577 ± 0.01	1.236ThrTyr: 1.236 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	7.798ValAla: 7.798 ± 0.047	1.087ValCys: 1.087 ± 0.019	3.781ValAsp: 3.781 ± 0.029	3.386ValGlu: 3.386 ± 0.033	2.51ValPhe: 2.51 ± 0.025	3.71ValGly: 3.71 ± 0.029	1.641ValHis: 1.641 ± 0.017	2.62ValIle: 2.62 ± 0.022	2.435ValLys: 2.435 ± 0.025	6.337ValLeu: 6.337 ± 0.041	1.294ValMet: 1.294 ± 0.016	2.393ValAsn: 2.393 ± 0.029	3.822ValPro: 3.822 ± 0.029	2.816ValGln: 2.816 ± 0.027	3.757ValArg: 3.757 ± 0.028	5.453ValSer: 5.453 ± 0.044	3.875ValThr: 3.875 ± 0.035	5.222ValVal: 5.222 ± 0.034	0.671ValTrp: 0.671 ± 0.011	1.544ValTyr: 1.544 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	0.723TrpAla: 0.723 ± 0.011	0.18TrpCys: 0.18 ± 0.005	0.528TrpAsp: 0.528 ± 0.01	0.452TrpGlu: 0.452 ± 0.009	0.394TrpPhe: 0.394 ± 0.007	0.445TrpGly: 0.445 ± 0.01	0.272TrpHis: 0.272 ± 0.008	0.473TrpIle: 0.473 ± 0.009	0.413TrpLys: 0.413 ± 0.01	1.086TrpLeu: 1.086 ± 0.014	0.307TrpMet: 0.307 ± 0.008	0.439TrpAsn: 0.439 ± 0.009	0.406TrpPro: 0.406 ± 0.009	0.476TrpGln: 0.476 ± 0.011	0.67TrpArg: 0.67 ± 0.012	0.845TrpSer: 0.845 ± 0.013	0.642TrpThr: 0.642 ± 0.011	0.557TrpVal: 0.557 ± 0.011	0.17TrpTrp: 0.17 ± 0.006	0.258TrpTyr: 0.258 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.943TyrAla: 1.943 ± 0.021	0.399TyrCys: 0.399 ± 0.01	1.258TyrAsp: 1.258 ± 0.018	1.098TyrGlu: 1.098 ± 0.015	0.933TyrPhe: 0.933 ± 0.013	1.417TyrGly: 1.417 ± 0.019	0.572TyrHis: 0.572 ± 0.012	0.929TyrIle: 0.929 ± 0.014	0.765TyrLys: 0.765 ± 0.013	2.163TyrLeu: 2.163 ± 0.023	0.496TyrMet: 0.496 ± 0.009	0.89TyrAsn: 0.89 ± 0.013	0.919TyrPro: 0.919 ± 0.016	0.9TyrGln: 0.9 ± 0.015	1.236TyrArg: 1.236 ± 0.016	1.605TyrSer: 1.605 ± 0.022	1.185TyrThr: 1.185 ± 0.015	1.387TyrVal: 1.387 ± 0.016	0.259TyrTrp: 0.259 ± 0.007	0.678TyrTyr: 0.678 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9794 proteins (6129802 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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