Amino acid dipepetide frequency for Rosavirus A2 (isolate Human/Gambia/GA7403/2008)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.702AlaAla: 7.702 ± 0.0
0.811AlaCys: 0.811 ± 0.0
3.648AlaAsp: 3.648 ± 0.0
3.243AlaGlu: 3.243 ± 0.0
3.243AlaPhe: 3.243 ± 0.0
5.27AlaGly: 5.27 ± 0.0
1.216AlaHis: 1.216 ± 0.0
2.027AlaIle: 2.027 ± 0.0
4.054AlaLys: 4.054 ± 0.0
6.891AlaLeu: 6.891 ± 0.0
3.648AlaMet: 3.648 ± 0.0
3.243AlaAsn: 3.243 ± 0.0
6.486AlaPro: 6.486 ± 0.0
2.837AlaGln: 2.837 ± 0.0
6.486AlaArg: 6.486 ± 0.0
5.675AlaSer: 5.675 ± 0.0
5.675AlaThr: 5.675 ± 0.0
6.08AlaVal: 6.08 ± 0.0
1.216AlaTrp: 1.216 ± 0.0
4.459AlaTyr: 4.459 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.216CysAla: 1.216 ± 0.0
0.811CysCys: 0.811 ± 0.0
0.811CysAsp: 0.811 ± 0.0
1.216CysGlu: 1.216 ± 0.0
2.027CysPhe: 2.027 ± 0.0
1.621CysGly: 1.621 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.811CysIle: 0.811 ± 0.0
0.405CysLys: 0.405 ± 0.0
1.216CysLeu: 1.216 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.621CysAsn: 1.621 ± 0.0
1.216CysPro: 1.216 ± 0.0
1.216CysGln: 1.216 ± 0.0
1.216CysArg: 1.216 ± 0.0
2.837CysSer: 2.837 ± 0.0
0.405CysThr: 0.405 ± 0.0
2.837CysVal: 2.837 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.216CysTyr: 1.216 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.459AspAla: 4.459 ± 0.0
1.621AspCys: 1.621 ± 0.0
1.621AspAsp: 1.621 ± 0.0
2.837AspGlu: 2.837 ± 0.0
3.648AspPhe: 3.648 ± 0.0
7.702AspGly: 7.702 ± 0.0
0.811AspHis: 0.811 ± 0.0
2.432AspIle: 2.432 ± 0.0
1.621AspLys: 1.621 ± 0.0
4.459AspLeu: 4.459 ± 0.0
1.621AspMet: 1.621 ± 0.0
2.027AspAsn: 2.027 ± 0.0
5.675AspPro: 5.675 ± 0.0
1.216AspGln: 1.216 ± 0.0
2.432AspArg: 2.432 ± 0.0
2.432AspSer: 2.432 ± 0.0
2.837AspThr: 2.837 ± 0.0
2.432AspVal: 2.432 ± 0.0
1.216AspTrp: 1.216 ± 0.0
1.621AspTyr: 1.621 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
6.08GluAla: 6.08 ± 0.0
0.811GluCys: 0.811 ± 0.0
1.621GluAsp: 1.621 ± 0.0
2.432GluGlu: 2.432 ± 0.0
1.216GluPhe: 1.216 ± 0.0
3.648GluGly: 3.648 ± 0.0
0.405GluHis: 0.405 ± 0.0
1.621GluIle: 1.621 ± 0.0
1.621GluLys: 1.621 ± 0.0
2.837GluLeu: 2.837 ± 0.0
0.0GluMet: 0.0 ± 0.0
2.432GluAsn: 2.432 ± 0.0
3.243GluPro: 3.243 ± 0.0
2.432GluGln: 2.432 ± 0.0
1.621GluArg: 1.621 ± 0.0
3.243GluSer: 3.243 ± 0.0
3.648GluThr: 3.648 ± 0.0
2.837GluVal: 2.837 ± 0.0
0.811GluTrp: 0.811 ± 0.0
1.216GluTyr: 1.216 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
4.459PheAla: 4.459 ± 0.0
2.027PheCys: 2.027 ± 0.0
2.837PheAsp: 2.837 ± 0.0
2.027PheGlu: 2.027 ± 0.0
2.027PhePhe: 2.027 ± 0.0
1.216PheGly: 1.216 ± 0.0
2.027PheHis: 2.027 ± 0.0
1.216PheIle: 1.216 ± 0.0
2.027PheLys: 2.027 ± 0.0
2.432PheLeu: 2.432 ± 0.0
0.0PheMet: 0.0 ± 0.0
2.837PheAsn: 2.837 ± 0.0
4.864PhePro: 4.864 ± 0.0
1.621PheGln: 1.621 ± 0.0
1.216PheArg: 1.216 ± 0.0
5.675PheSer: 5.675 ± 0.0
3.648PheThr: 3.648 ± 0.0
3.243PheVal: 3.243 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.811PheTyr: 0.811 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.675GlyAla: 5.675 ± 0.0
2.837GlyCys: 2.837 ± 0.0
5.27GlyAsp: 5.27 ± 0.0
3.243GlyGlu: 3.243 ± 0.0
2.432GlyPhe: 2.432 ± 0.0
3.243GlyGly: 3.243 ± 0.0
0.811GlyHis: 0.811 ± 0.0
3.243GlyIle: 3.243 ± 0.0
2.837GlyLys: 2.837 ± 0.0
8.512GlyLeu: 8.512 ± 0.0
0.811GlyMet: 0.811 ± 0.0
1.621GlyAsn: 1.621 ± 0.0
3.243GlyPro: 3.243 ± 0.0
2.432GlyGln: 2.432 ± 0.0
2.837GlyArg: 2.837 ± 0.0
4.459GlySer: 4.459 ± 0.0
6.08GlyThr: 6.08 ± 0.0
4.459GlyVal: 4.459 ± 0.0
0.405GlyTrp: 0.405 ± 0.0
2.837GlyTyr: 2.837 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.216HisAla: 1.216 ± 0.0
0.405HisCys: 0.405 ± 0.0
0.405HisAsp: 0.405 ± 0.0
0.405HisGlu: 0.405 ± 0.0
1.216HisPhe: 1.216 ± 0.0
2.027HisGly: 2.027 ± 0.0
0.811HisHis: 0.811 ± 0.0
1.216HisIle: 1.216 ± 0.0
0.811HisLys: 0.811 ± 0.0
1.216HisLeu: 1.216 ± 0.0
0.811HisMet: 0.811 ± 0.0
1.216HisAsn: 1.216 ± 0.0
1.621HisPro: 1.621 ± 0.0
0.405HisGln: 0.405 ± 0.0
0.811HisArg: 0.811 ± 0.0
1.621HisSer: 1.621 ± 0.0
1.621HisThr: 1.621 ± 0.0
1.621HisVal: 1.621 ± 0.0
1.621HisTrp: 1.621 ± 0.0
0.405HisTyr: 0.405 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.864IleAla: 4.864 ± 0.0
1.621IleCys: 1.621 ± 0.0
3.648IleAsp: 3.648 ± 0.0
0.0IleGlu: 0.0 ± 0.0
0.811IlePhe: 0.811 ± 0.0
2.027IleGly: 2.027 ± 0.0
1.216IleHis: 1.216 ± 0.0
1.216IleIle: 1.216 ± 0.0
0.811IleLys: 0.811 ± 0.0
1.621IleLeu: 1.621 ± 0.0
0.0IleMet: 0.0 ± 0.0
2.837IleAsn: 2.837 ± 0.0
6.08IlePro: 6.08 ± 0.0
1.216IleGln: 1.216 ± 0.0
0.405IleArg: 0.405 ± 0.0
4.054IleSer: 4.054 ± 0.0
2.027IleThr: 2.027 ± 0.0
2.027IleVal: 2.027 ± 0.0
0.405IleTrp: 0.405 ± 0.0
0.811IleTyr: 0.811 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.432LysAla: 2.432 ± 0.0
0.0LysCys: 0.0 ± 0.0
2.432LysAsp: 2.432 ± 0.0
2.837LysGlu: 2.837 ± 0.0
2.432LysPhe: 2.432 ± 0.0
1.621LysGly: 1.621 ± 0.0
1.216LysHis: 1.216 ± 0.0
2.027LysIle: 2.027 ± 0.0
3.243LysLys: 3.243 ± 0.0
4.864LysLeu: 4.864 ± 0.0
0.0LysMet: 0.0 ± 0.0
1.216LysAsn: 1.216 ± 0.0
2.432LysPro: 2.432 ± 0.0
0.405LysGln: 0.405 ± 0.0
0.811LysArg: 0.811 ± 0.0
3.648LysSer: 3.648 ± 0.0
4.054LysThr: 4.054 ± 0.0
4.459LysVal: 4.459 ± 0.0
0.405LysTrp: 0.405 ± 0.0
1.216LysTyr: 1.216 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.486LeuAla: 6.486 ± 0.0
1.621LeuCys: 1.621 ± 0.0
4.864LeuAsp: 4.864 ± 0.0
3.648LeuGlu: 3.648 ± 0.0
3.648LeuPhe: 3.648 ± 0.0
5.675LeuGly: 5.675 ± 0.0
0.405LeuHis: 0.405 ± 0.0
2.027LeuIle: 2.027 ± 0.0
4.864LeuLys: 4.864 ± 0.0
9.728LeuLeu: 9.728 ± 0.0
1.216LeuMet: 1.216 ± 0.0
1.216LeuAsn: 1.216 ± 0.0
5.27LeuPro: 5.27 ± 0.0
2.432LeuGln: 2.432 ± 0.0
5.27LeuArg: 5.27 ± 0.0
6.891LeuSer: 6.891 ± 0.0
4.459LeuThr: 4.459 ± 0.0
8.107LeuVal: 8.107 ± 0.0
1.216LeuTrp: 1.216 ± 0.0
1.621LeuTyr: 1.621 ± 0.0
0.405LeuXaa: 0.405 ± 0.0
Met
2.027MetAla: 2.027 ± 0.0
1.216MetCys: 1.216 ± 0.0
1.216MetAsp: 1.216 ± 0.0
0.405MetGlu: 0.405 ± 0.0
0.405MetPhe: 0.405 ± 0.0
2.027MetGly: 2.027 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.811MetIle: 0.811 ± 0.0
1.216MetLys: 1.216 ± 0.0
1.621MetLeu: 1.621 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.405MetAsn: 0.405 ± 0.0
1.621MetPro: 1.621 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.621MetSer: 1.621 ± 0.0
0.811MetThr: 0.811 ± 0.0
1.216MetVal: 1.216 ± 0.0
0.405MetTrp: 0.405 ± 0.0
0.811MetTyr: 0.811 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.243AsnAla: 3.243 ± 0.0
1.216AsnCys: 1.216 ± 0.0
1.621AsnAsp: 1.621 ± 0.0
0.405AsnGlu: 0.405 ± 0.0
3.243AsnPhe: 3.243 ± 0.0
2.837AsnGly: 2.837 ± 0.0
0.811AsnHis: 0.811 ± 0.0
2.027AsnIle: 2.027 ± 0.0
0.811AsnLys: 0.811 ± 0.0
4.054AsnLeu: 4.054 ± 0.0
1.216AsnMet: 1.216 ± 0.0
1.216AsnAsn: 1.216 ± 0.0
3.243AsnPro: 3.243 ± 0.0
1.216AsnGln: 1.216 ± 0.0
0.811AsnArg: 0.811 ± 0.0
3.648AsnSer: 3.648 ± 0.0
1.621AsnThr: 1.621 ± 0.0
3.243AsnVal: 3.243 ± 0.0
0.811AsnTrp: 0.811 ± 0.0
2.027AsnTyr: 2.027 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.459ProAla: 4.459 ± 0.0
0.811ProCys: 0.811 ± 0.0
3.648ProAsp: 3.648 ± 0.0
3.648ProGlu: 3.648 ± 0.0
3.648ProPhe: 3.648 ± 0.0
6.486ProGly: 6.486 ± 0.0
2.027ProHis: 2.027 ± 0.0
2.837ProIle: 2.837 ± 0.0
2.432ProLys: 2.432 ± 0.0
4.864ProLeu: 4.864 ± 0.0
0.0ProMet: 0.0 ± 0.0
2.837ProAsn: 2.837 ± 0.0
3.648ProPro: 3.648 ± 0.0
2.432ProGln: 2.432 ± 0.0
2.837ProArg: 2.837 ± 0.0
5.675ProSer: 5.675 ± 0.0
9.323ProThr: 9.323 ± 0.0
6.486ProVal: 6.486 ± 0.0
0.405ProTrp: 0.405 ± 0.0
2.837ProTyr: 2.837 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
6.08GlnAla: 6.08 ± 0.0
0.0GlnCys: 0.0 ± 0.0
2.432GlnAsp: 2.432 ± 0.0
1.621GlnGlu: 1.621 ± 0.0
2.432GlnPhe: 2.432 ± 0.0
1.216GlnGly: 1.216 ± 0.0
0.405GlnHis: 0.405 ± 0.0
2.837GlnIle: 2.837 ± 0.0
2.027GlnLys: 2.027 ± 0.0
0.811GlnLeu: 0.811 ± 0.0
0.811GlnMet: 0.811 ± 0.0
0.405GlnAsn: 0.405 ± 0.0
2.432GlnPro: 2.432 ± 0.0
1.216GlnGln: 1.216 ± 0.0
1.216GlnArg: 1.216 ± 0.0
3.243GlnSer: 3.243 ± 0.0
2.027GlnThr: 2.027 ± 0.0
2.027GlnVal: 2.027 ± 0.0
1.621GlnTrp: 1.621 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.243ArgAla: 3.243 ± 0.0
0.405ArgCys: 0.405 ± 0.0
3.243ArgAsp: 3.243 ± 0.0
2.027ArgGlu: 2.027 ± 0.0
2.027ArgPhe: 2.027 ± 0.0
2.837ArgGly: 2.837 ± 0.0
1.621ArgHis: 1.621 ± 0.0
0.405ArgIle: 0.405 ± 0.0
3.648ArgLys: 3.648 ± 0.0
4.054ArgLeu: 4.054 ± 0.0
1.216ArgMet: 1.216 ± 0.0
1.621ArgAsn: 1.621 ± 0.0
1.216ArgPro: 1.216 ± 0.0
1.621ArgGln: 1.621 ± 0.0
1.621ArgArg: 1.621 ± 0.0
2.837ArgSer: 2.837 ± 0.0
3.243ArgThr: 3.243 ± 0.0
5.27ArgVal: 5.27 ± 0.0
1.621ArgTrp: 1.621 ± 0.0
2.432ArgTyr: 2.432 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
7.702SerAla: 7.702 ± 0.0
0.811SerCys: 0.811 ± 0.0
4.864SerAsp: 4.864 ± 0.0
4.054SerGlu: 4.054 ± 0.0
2.432SerPhe: 2.432 ± 0.0
3.648SerGly: 3.648 ± 0.0
1.216SerHis: 1.216 ± 0.0
3.243SerIle: 3.243 ± 0.0
2.432SerLys: 2.432 ± 0.0
7.702SerLeu: 7.702 ± 0.0
1.621SerMet: 1.621 ± 0.0
2.837SerAsn: 2.837 ± 0.0
5.675SerPro: 5.675 ± 0.0
4.864SerGln: 4.864 ± 0.0
3.648SerArg: 3.648 ± 0.0
7.296SerSer: 7.296 ± 0.0
4.459SerThr: 4.459 ± 0.0
11.35SerVal: 11.35 ± 0.0
1.621SerTrp: 1.621 ± 0.0
1.621SerTyr: 1.621 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
2.837ThrAla: 2.837 ± 0.0
0.405ThrCys: 0.405 ± 0.0
2.837ThrAsp: 2.837 ± 0.0
2.432ThrGlu: 2.432 ± 0.0
4.054ThrPhe: 4.054 ± 0.0
5.27ThrGly: 5.27 ± 0.0
2.432ThrHis: 2.432 ± 0.0
2.837ThrIle: 2.837 ± 0.0
1.621ThrLys: 1.621 ± 0.0
6.08ThrLeu: 6.08 ± 0.0
1.621ThrMet: 1.621 ± 0.0
2.432ThrAsn: 2.432 ± 0.0
6.891ThrPro: 6.891 ± 0.0
1.216ThrGln: 1.216 ± 0.0
3.243ThrArg: 3.243 ± 0.0
6.891ThrSer: 6.891 ± 0.0
5.27ThrThr: 5.27 ± 0.0
5.675ThrVal: 5.675 ± 0.0
1.621ThrTrp: 1.621 ± 0.0
2.837ThrTyr: 2.837 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
6.891ValAla: 6.891 ± 0.0
3.648ValCys: 3.648 ± 0.0
5.675ValAsp: 5.675 ± 0.0
2.837ValGlu: 2.837 ± 0.0
3.648ValPhe: 3.648 ± 0.0
4.459ValGly: 4.459 ± 0.0
2.432ValHis: 2.432 ± 0.0
2.027ValIle: 2.027 ± 0.0
4.054ValLys: 4.054 ± 0.0
5.675ValLeu: 5.675 ± 0.0
2.027ValMet: 2.027 ± 0.0
4.054ValAsn: 4.054 ± 0.0
4.054ValPro: 4.054 ± 0.0
3.648ValGln: 3.648 ± 0.0
6.08ValArg: 6.08 ± 0.0
7.296ValSer: 7.296 ± 0.0
4.054ValThr: 4.054 ± 0.0
6.891ValVal: 6.891 ± 0.0
1.216ValTrp: 1.216 ± 0.0
4.054ValTyr: 4.054 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.405TrpAla: 0.405 ± 0.0
0.405TrpCys: 0.405 ± 0.0
0.405TrpAsp: 0.405 ± 0.0
0.811TrpGlu: 0.811 ± 0.0
0.405TrpPhe: 0.405 ± 0.0
1.216TrpGly: 1.216 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.811TrpIle: 0.811 ± 0.0
0.811TrpLys: 0.811 ± 0.0
1.216TrpLeu: 1.216 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.811TrpAsn: 0.811 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.216TrpGln: 1.216 ± 0.0
2.027TrpArg: 2.027 ± 0.0
2.027TrpSer: 2.027 ± 0.0
1.216TrpThr: 1.216 ± 0.0
2.027TrpVal: 2.027 ± 0.0
0.811TrpTrp: 0.811 ± 0.0
1.621TrpTyr: 1.621 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.432TyrAla: 2.432 ± 0.0
1.216TyrCys: 1.216 ± 0.0
1.621TyrAsp: 1.621 ± 0.0
3.648TyrGlu: 3.648 ± 0.0
1.216TyrPhe: 1.216 ± 0.0
2.837TyrGly: 2.837 ± 0.0
1.621TyrHis: 1.621 ± 0.0
2.027TyrIle: 2.027 ± 0.0
0.405TyrLys: 0.405 ± 0.0
1.216TyrLeu: 1.216 ± 0.0
0.811TyrMet: 0.811 ± 0.0
2.432TyrAsn: 2.432 ± 0.0
2.432TyrPro: 2.432 ± 0.0
1.621TyrGln: 1.621 ± 0.0
1.621TyrArg: 1.621 ± 0.0
2.027TyrSer: 2.027 ± 0.0
2.027TyrThr: 2.027 ± 0.0
2.432TyrVal: 2.432 ± 0.0
0.811TyrTrp: 0.811 ± 0.0
0.405TyrTyr: 0.405 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.405XaaGly: 0.405 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2468 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski