Amino acid dipepetide frequency for Mesorhizobium phage Cp1R7A-A1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.509AlaAla: 11.509 ± 0.893
0.813AlaCys: 0.813 ± 0.122
6.58AlaAsp: 6.58 ± 0.423
6.816AlaGlu: 6.816 ± 0.551
3.644AlaPhe: 3.644 ± 0.282
7.0AlaGly: 7.0 ± 0.5
1.861AlaHis: 1.861 ± 0.255
5.532AlaIle: 5.532 ± 0.406
6.554AlaLys: 6.554 ± 0.557
7.918AlaLeu: 7.918 ± 0.531
3.906AlaMet: 3.906 ± 0.307
3.644AlaAsn: 3.644 ± 0.347
4.116AlaPro: 4.116 ± 0.539
3.67AlaGln: 3.67 ± 0.36
5.06AlaArg: 5.06 ± 0.361
5.139AlaSer: 5.139 ± 0.438
5.689AlaThr: 5.689 ± 0.551
6.423AlaVal: 6.423 ± 0.473
1.573AlaTrp: 1.573 ± 0.213
2.622AlaTyr: 2.622 ± 0.294
0.0AlaXaa: 0.0 ± 0.0
Cys
0.918CysAla: 0.918 ± 0.139
0.131CysCys: 0.131 ± 0.061
0.708CysAsp: 0.708 ± 0.136
0.524CysGlu: 0.524 ± 0.11
0.577CysPhe: 0.577 ± 0.126
0.577CysGly: 0.577 ± 0.121
0.236CysHis: 0.236 ± 0.104
0.524CysIle: 0.524 ± 0.126
0.472CysLys: 0.472 ± 0.112
0.76CysLeu: 0.76 ± 0.168
0.105CysMet: 0.105 ± 0.062
0.341CysAsn: 0.341 ± 0.108
0.524CysPro: 0.524 ± 0.117
0.131CysGln: 0.131 ± 0.057
0.655CysArg: 0.655 ± 0.148
0.524CysSer: 0.524 ± 0.124
0.629CysThr: 0.629 ± 0.133
0.813CysVal: 0.813 ± 0.129
0.157CysTrp: 0.157 ± 0.063
0.157CysTyr: 0.157 ± 0.058
0.0CysXaa: 0.0 ± 0.0
Asp
6.79AspAla: 6.79 ± 0.427
0.734AspCys: 0.734 ± 0.13
4.745AspAsp: 4.745 ± 0.389
4.588AspGlu: 4.588 ± 0.366
3.094AspPhe: 3.094 ± 0.307
5.479AspGly: 5.479 ± 0.413
1.599AspHis: 1.599 ± 0.206
3.513AspIle: 3.513 ± 0.393
2.727AspLys: 2.727 ± 0.29
5.27AspLeu: 5.27 ± 0.375
1.861AspMet: 1.861 ± 0.237
2.36AspAsn: 2.36 ± 0.265
4.064AspPro: 4.064 ± 0.395
1.809AspGln: 1.809 ± 0.2
3.985AspArg: 3.985 ± 0.334
3.461AspSer: 3.461 ± 0.282
3.277AspThr: 3.277 ± 0.312
3.906AspVal: 3.906 ± 0.398
1.599AspTrp: 1.599 ± 0.199
1.966AspTyr: 1.966 ± 0.207
0.0AspXaa: 0.0 ± 0.0
Glu
6.056GluAla: 6.056 ± 0.431
0.603GluCys: 0.603 ± 0.132
4.037GluAsp: 4.037 ± 0.425
4.404GluGlu: 4.404 ± 0.444
2.307GluPhe: 2.307 ± 0.226
3.854GluGly: 3.854 ± 0.365
1.573GluHis: 1.573 ± 0.164
4.142GluIle: 4.142 ± 0.331
3.697GluLys: 3.697 ± 0.395
5.165GluLeu: 5.165 ± 0.419
1.757GluMet: 1.757 ± 0.247
2.071GluAsn: 2.071 ± 0.216
2.307GluPro: 2.307 ± 0.28
2.307GluGln: 2.307 ± 0.242
3.566GluArg: 3.566 ± 0.389
3.015GluSer: 3.015 ± 0.332
3.644GluThr: 3.644 ± 0.324
4.903GluVal: 4.903 ± 0.343
1.39GluTrp: 1.39 ± 0.169
1.547GluTyr: 1.547 ± 0.212
0.0GluXaa: 0.0 ± 0.0
Phe
3.854PheAla: 3.854 ± 0.348
0.341PheCys: 0.341 ± 0.111
3.094PheAsp: 3.094 ± 0.282
2.7PheGlu: 2.7 ± 0.31
1.363PhePhe: 1.363 ± 0.158
3.198PheGly: 3.198 ± 0.294
0.708PheHis: 0.708 ± 0.146
1.94PheIle: 1.94 ± 0.207
1.993PheLys: 1.993 ± 0.24
2.543PheLeu: 2.543 ± 0.282
0.918PheMet: 0.918 ± 0.163
1.625PheAsn: 1.625 ± 0.211
1.888PhePro: 1.888 ± 0.223
1.18PheGln: 1.18 ± 0.197
2.412PheArg: 2.412 ± 0.286
2.464PheSer: 2.464 ± 0.26
2.307PheThr: 2.307 ± 0.266
2.648PheVal: 2.648 ± 0.26
0.682PheTrp: 0.682 ± 0.124
0.891PheTyr: 0.891 ± 0.163
0.0PheXaa: 0.0 ± 0.0
Gly
6.554GlyAla: 6.554 ± 0.473
0.76GlyCys: 0.76 ± 0.159
4.745GlyAsp: 4.745 ± 0.32
4.09GlyGlu: 4.09 ± 0.359
3.356GlyPhe: 3.356 ± 0.285
6.004GlyGly: 6.004 ± 0.615
1.442GlyHis: 1.442 ± 0.221
3.225GlyIle: 3.225 ± 0.323
5.348GlyLys: 5.348 ± 0.317
6.476GlyLeu: 6.476 ± 0.547
2.438GlyMet: 2.438 ± 0.296
2.727GlyAsn: 2.727 ± 0.305
2.595GlyPro: 2.595 ± 0.276
2.753GlyGln: 2.753 ± 0.3
4.798GlyArg: 4.798 ± 0.348
5.348GlySer: 5.348 ± 0.459
5.191GlyThr: 5.191 ± 0.536
5.427GlyVal: 5.427 ± 0.358
1.075GlyTrp: 1.075 ± 0.156
2.386GlyTyr: 2.386 ± 0.256
0.0GlyXaa: 0.0 ± 0.0
His
1.94HisAla: 1.94 ± 0.217
0.367HisCys: 0.367 ± 0.088
1.835HisAsp: 1.835 ± 0.208
1.049HisGlu: 1.049 ± 0.173
0.996HisPhe: 0.996 ± 0.162
1.652HisGly: 1.652 ± 0.232
0.472HisHis: 0.472 ± 0.114
0.734HisIle: 0.734 ± 0.169
1.127HisLys: 1.127 ± 0.186
1.573HisLeu: 1.573 ± 0.171
0.603HisMet: 0.603 ± 0.117
0.97HisAsn: 0.97 ± 0.164
1.206HisPro: 1.206 ± 0.191
0.629HisGln: 0.629 ± 0.147
1.311HisArg: 1.311 ± 0.199
0.97HisSer: 0.97 ± 0.171
0.813HisThr: 0.813 ± 0.18
1.573HisVal: 1.573 ± 0.213
0.262HisTrp: 0.262 ± 0.08
0.682HisTyr: 0.682 ± 0.144
0.0HisXaa: 0.0 ± 0.0
Ile
5.479IleAla: 5.479 ± 0.447
0.498IleCys: 0.498 ± 0.134
4.195IleAsp: 4.195 ± 0.318
4.169IleGlu: 4.169 ± 0.346
1.573IlePhe: 1.573 ± 0.219
4.195IleGly: 4.195 ± 0.349
1.075IleHis: 1.075 ± 0.163
2.595IleIle: 2.595 ± 0.258
2.517IleLys: 2.517 ± 0.302
3.251IleLeu: 3.251 ± 0.297
0.944IleMet: 0.944 ± 0.151
1.966IleAsn: 1.966 ± 0.265
2.019IlePro: 2.019 ± 0.224
1.521IleGln: 1.521 ± 0.203
3.513IleArg: 3.513 ± 0.319
3.303IleSer: 3.303 ± 0.338
3.566IleThr: 3.566 ± 0.443
4.483IleVal: 4.483 ± 0.389
0.787IleTrp: 0.787 ± 0.155
0.839IleTyr: 0.839 ± 0.15
0.0IleXaa: 0.0 ± 0.0
Lys
6.213LysAla: 6.213 ± 0.567
0.393LysCys: 0.393 ± 0.101
3.644LysAsp: 3.644 ± 0.295
3.146LysGlu: 3.146 ± 0.329
1.73LysPhe: 1.73 ± 0.212
3.513LysGly: 3.513 ± 0.284
1.022LysHis: 1.022 ± 0.189
2.543LysIle: 2.543 ± 0.199
3.146LysLys: 3.146 ± 0.342
5.689LysLeu: 5.689 ± 0.357
1.311LysMet: 1.311 ± 0.191
1.547LysAsn: 1.547 ± 0.212
2.674LysPro: 2.674 ± 0.355
1.573LysGln: 1.573 ± 0.181
3.382LysArg: 3.382 ± 0.363
3.146LysSer: 3.146 ± 0.309
3.356LysThr: 3.356 ± 0.316
3.854LysVal: 3.854 ± 0.304
0.97LysTrp: 0.97 ± 0.175
1.206LysTyr: 1.206 ± 0.154
0.0LysXaa: 0.0 ± 0.0
Leu
7.603LeuAla: 7.603 ± 0.457
0.787LeuCys: 0.787 ± 0.145
5.112LeuAsp: 5.112 ± 0.46
4.981LeuGlu: 4.981 ± 0.403
3.015LeuPhe: 3.015 ± 0.314
6.423LeuGly: 6.423 ± 0.43
1.547LeuHis: 1.547 ± 0.182
4.431LeuIle: 4.431 ± 0.364
3.566LeuLys: 3.566 ± 0.346
5.715LeuLeu: 5.715 ± 0.396
1.861LeuMet: 1.861 ± 0.264
3.172LeuAsn: 3.172 ± 0.315
4.457LeuPro: 4.457 ± 0.351
2.071LeuGln: 2.071 ± 0.269
5.375LeuArg: 5.375 ± 0.396
4.798LeuSer: 4.798 ± 0.373
6.318LeuThr: 6.318 ± 0.474
4.798LeuVal: 4.798 ± 0.381
1.154LeuTrp: 1.154 ± 0.171
2.071LeuTyr: 2.071 ± 0.215
0.0LeuXaa: 0.0 ± 0.0
Met
2.884MetAla: 2.884 ± 0.306
0.184MetCys: 0.184 ± 0.072
1.494MetAsp: 1.494 ± 0.178
1.258MetGlu: 1.258 ± 0.216
1.232MetPhe: 1.232 ± 0.174
1.704MetGly: 1.704 ± 0.211
0.629MetHis: 0.629 ± 0.132
1.337MetIle: 1.337 ± 0.182
1.835MetLys: 1.835 ± 0.219
2.255MetLeu: 2.255 ± 0.231
0.865MetMet: 0.865 ± 0.187
1.049MetAsn: 1.049 ± 0.179
1.468MetPro: 1.468 ± 0.212
0.944MetGln: 0.944 ± 0.147
1.861MetArg: 1.861 ± 0.24
2.097MetSer: 2.097 ± 0.236
2.228MetThr: 2.228 ± 0.267
1.704MetVal: 1.704 ± 0.2
0.315MetTrp: 0.315 ± 0.094
0.577MetTyr: 0.577 ± 0.128
0.0MetXaa: 0.0 ± 0.0
Asn
4.195AsnAla: 4.195 ± 0.569
0.419AsnCys: 0.419 ± 0.097
2.15AsnAsp: 2.15 ± 0.226
1.783AsnGlu: 1.783 ± 0.278
0.996AsnPhe: 0.996 ± 0.147
3.854AsnGly: 3.854 ± 0.408
0.865AsnHis: 0.865 ± 0.15
1.39AsnIle: 1.39 ± 0.176
1.547AsnLys: 1.547 ± 0.263
2.884AsnLeu: 2.884 ± 0.263
0.996AsnMet: 0.996 ± 0.187
1.652AsnAsn: 1.652 ± 0.238
2.307AsnPro: 2.307 ± 0.224
1.101AsnGln: 1.101 ± 0.158
2.097AsnArg: 2.097 ± 0.244
1.861AsnSer: 1.861 ± 0.189
1.861AsnThr: 1.861 ± 0.254
2.255AsnVal: 2.255 ± 0.219
0.918AsnTrp: 0.918 ± 0.165
0.97AsnTyr: 0.97 ± 0.177
0.0AsnXaa: 0.0 ± 0.0
Pro
5.139ProAla: 5.139 ± 0.451
0.393ProCys: 0.393 ± 0.107
3.172ProAsp: 3.172 ± 0.333
3.356ProGlu: 3.356 ± 0.334
1.757ProPhe: 1.757 ± 0.244
3.67ProGly: 3.67 ± 0.347
1.206ProHis: 1.206 ± 0.187
2.464ProIle: 2.464 ± 0.294
2.831ProLys: 2.831 ± 0.427
3.067ProLeu: 3.067 ± 0.298
1.258ProMet: 1.258 ± 0.185
1.494ProAsn: 1.494 ± 0.217
1.993ProPro: 1.993 ± 0.286
1.18ProGln: 1.18 ± 0.176
1.888ProArg: 1.888 ± 0.247
3.041ProSer: 3.041 ± 0.375
3.198ProThr: 3.198 ± 0.298
3.933ProVal: 3.933 ± 0.399
0.551ProTrp: 0.551 ± 0.125
1.835ProTyr: 1.835 ± 0.222
0.0ProXaa: 0.0 ± 0.0
Gln
3.198GlnAla: 3.198 ± 0.304
0.157GlnCys: 0.157 ± 0.051
1.521GlnAsp: 1.521 ± 0.164
1.573GlnGlu: 1.573 ± 0.196
1.337GlnPhe: 1.337 ± 0.192
1.783GlnGly: 1.783 ± 0.188
0.419GlnHis: 0.419 ± 0.106
2.386GlnIle: 2.386 ± 0.242
1.757GlnLys: 1.757 ± 0.248
2.15GlnLeu: 2.15 ± 0.244
1.022GlnMet: 1.022 ± 0.156
1.049GlnAsn: 1.049 ± 0.177
1.704GlnPro: 1.704 ± 0.234
1.127GlnGln: 1.127 ± 0.211
2.36GlnArg: 2.36 ± 0.304
1.914GlnSer: 1.914 ± 0.198
2.307GlnThr: 2.307 ± 0.299
2.281GlnVal: 2.281 ± 0.177
0.944GlnTrp: 0.944 ± 0.197
1.049GlnTyr: 1.049 ± 0.154
0.0GlnXaa: 0.0 ± 0.0
Arg
5.61ArgAla: 5.61 ± 0.435
0.551ArgCys: 0.551 ± 0.112
3.487ArgAsp: 3.487 ± 0.29
3.487ArgGlu: 3.487 ± 0.404
2.858ArgPhe: 2.858 ± 0.275
3.959ArgGly: 3.959 ± 0.265
1.337ArgHis: 1.337 ± 0.183
3.487ArgIle: 3.487 ± 0.311
3.067ArgLys: 3.067 ± 0.291
5.243ArgLeu: 5.243 ± 0.39
1.547ArgMet: 1.547 ± 0.213
2.464ArgAsn: 2.464 ± 0.257
2.779ArgPro: 2.779 ± 0.284
2.543ArgGln: 2.543 ± 0.31
3.985ArgArg: 3.985 ± 0.432
3.461ArgSer: 3.461 ± 0.273
3.041ArgThr: 3.041 ± 0.31
4.457ArgVal: 4.457 ± 0.354
1.258ArgTrp: 1.258 ± 0.205
1.888ArgTyr: 1.888 ± 0.241
0.0ArgXaa: 0.0 ± 0.0
Ser
6.004SerAla: 6.004 ± 0.467
0.393SerCys: 0.393 ± 0.099
3.749SerAsp: 3.749 ± 0.321
3.094SerGlu: 3.094 ± 0.323
2.412SerPhe: 2.412 ± 0.251
5.584SerGly: 5.584 ± 0.597
1.258SerHis: 1.258 ± 0.174
3.487SerIle: 3.487 ± 0.347
2.491SerLys: 2.491 ± 0.284
4.614SerLeu: 4.614 ± 0.322
1.625SerMet: 1.625 ± 0.185
2.228SerAsn: 2.228 ± 0.363
2.464SerPro: 2.464 ± 0.258
2.019SerGln: 2.019 ± 0.198
3.723SerArg: 3.723 ± 0.337
2.989SerSer: 2.989 ± 0.261
3.225SerThr: 3.225 ± 0.316
3.644SerVal: 3.644 ± 0.316
0.97SerTrp: 0.97 ± 0.16
1.625SerTyr: 1.625 ± 0.247
0.0SerXaa: 0.0 ± 0.0
Thr
6.266ThrAla: 6.266 ± 0.659
0.682ThrCys: 0.682 ± 0.143
4.116ThrAsp: 4.116 ± 0.325
3.88ThrGlu: 3.88 ± 0.298
2.438ThrPhe: 2.438 ± 0.295
5.873ThrGly: 5.873 ± 0.517
0.996ThrHis: 0.996 ± 0.164
3.277ThrIle: 3.277 ± 0.359
3.172ThrLys: 3.172 ± 0.28
4.876ThrLeu: 4.876 ± 0.406
1.494ThrMet: 1.494 ± 0.205
2.097ThrAsn: 2.097 ± 0.333
3.88ThrPro: 3.88 ± 0.356
1.547ThrGln: 1.547 ± 0.197
2.963ThrArg: 2.963 ± 0.262
2.805ThrSer: 2.805 ± 0.343
4.3ThrThr: 4.3 ± 0.473
4.85ThrVal: 4.85 ± 0.47
0.813ThrTrp: 0.813 ± 0.181
2.36ThrTyr: 2.36 ± 0.477
0.0ThrXaa: 0.0 ± 0.0
Val
6.109ValAla: 6.109 ± 0.452
0.524ValCys: 0.524 ± 0.134
5.27ValAsp: 5.27 ± 0.358
4.798ValGlu: 4.798 ± 0.338
2.333ValPhe: 2.333 ± 0.237
4.614ValGly: 4.614 ± 0.392
1.363ValHis: 1.363 ± 0.21
3.303ValIle: 3.303 ± 0.298
4.011ValLys: 4.011 ± 0.253
5.663ValLeu: 5.663 ± 0.359
2.124ValMet: 2.124 ± 0.25
2.176ValAsn: 2.176 ± 0.298
3.303ValPro: 3.303 ± 0.286
2.464ValGln: 2.464 ± 0.244
4.037ValArg: 4.037 ± 0.372
4.772ValSer: 4.772 ± 0.386
5.086ValThr: 5.086 ± 0.626
4.352ValVal: 4.352 ± 0.316
1.39ValTrp: 1.39 ± 0.214
1.888ValTyr: 1.888 ± 0.22
0.0ValXaa: 0.0 ± 0.0
Trp
1.547TrpAla: 1.547 ± 0.189
0.21TrpCys: 0.21 ± 0.071
1.258TrpAsp: 1.258 ± 0.179
1.049TrpGlu: 1.049 ± 0.164
0.813TrpPhe: 0.813 ± 0.121
1.154TrpGly: 1.154 ± 0.146
0.315TrpHis: 0.315 ± 0.096
1.022TrpIle: 1.022 ± 0.184
0.813TrpLys: 0.813 ± 0.141
1.914TrpLeu: 1.914 ± 0.228
0.367TrpMet: 0.367 ± 0.105
0.787TrpAsn: 0.787 ± 0.172
0.551TrpPro: 0.551 ± 0.124
0.551TrpGln: 0.551 ± 0.102
1.258TrpArg: 1.258 ± 0.196
1.101TrpSer: 1.101 ± 0.157
0.97TrpThr: 0.97 ± 0.141
1.232TrpVal: 1.232 ± 0.193
0.393TrpTrp: 0.393 ± 0.091
0.446TrpTyr: 0.446 ± 0.106
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.202TyrAla: 2.202 ± 0.243
0.524TyrCys: 0.524 ± 0.112
1.914TyrAsp: 1.914 ± 0.217
1.599TyrGlu: 1.599 ± 0.238
0.918TyrPhe: 0.918 ± 0.158
2.674TyrGly: 2.674 ± 0.308
0.839TyrHis: 0.839 ± 0.137
1.154TyrIle: 1.154 ± 0.188
1.39TyrLys: 1.39 ± 0.2
2.228TyrLeu: 2.228 ± 0.247
0.891TyrMet: 0.891 ± 0.169
0.682TyrAsn: 0.682 ± 0.149
1.127TyrPro: 1.127 ± 0.175
0.918TyrGln: 0.918 ± 0.142
2.281TyrArg: 2.281 ± 0.278
1.39TyrSer: 1.39 ± 0.2
1.678TyrThr: 1.678 ± 0.304
2.045TyrVal: 2.045 ± 0.229
0.551TyrTrp: 0.551 ± 0.133
0.629TyrTyr: 0.629 ± 0.161
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 210 proteins (38144 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski