Amino acid dipepetide frequency for Zunongwangia atlantica 22II14-10F7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.472AlaAla: 4.472 ± 0.07	0.469AlaCys: 0.469 ± 0.019	3.267AlaAsp: 3.267 ± 0.056	5.167AlaGlu: 5.167 ± 0.066	3.159AlaPhe: 3.159 ± 0.059	4.252AlaGly: 4.252 ± 0.054	1.056AlaHis: 1.056 ± 0.028	5.202AlaIle: 5.202 ± 0.07	4.764AlaLys: 4.764 ± 0.075	5.84AlaLeu: 5.84 ± 0.068	1.593AlaMet: 1.593 ± 0.034	3.477AlaAsn: 3.477 ± 0.054	1.899AlaPro: 1.899 ± 0.04	2.479AlaGln: 2.479 ± 0.048	2.08AlaArg: 2.08 ± 0.043	4.333AlaSer: 4.333 ± 0.068	3.312AlaThr: 3.312 ± 0.065	4.018AlaVal: 4.018 ± 0.067	0.666AlaTrp: 0.666 ± 0.024	2.566AlaTyr: 2.566 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	0.389CysAla: 0.389 ± 0.018	0.109CysCys: 0.109 ± 0.01	0.362CysAsp: 0.362 ± 0.015	0.431CysGlu: 0.431 ± 0.019	0.394CysPhe: 0.394 ± 0.018	0.551CysGly: 0.551 ± 0.021	0.141CysHis: 0.141 ± 0.01	0.509CysIle: 0.509 ± 0.02	0.431CysLys: 0.431 ± 0.017	0.586CysLeu: 0.586 ± 0.02	0.116CysMet: 0.116 ± 0.008	0.318CysAsn: 0.318 ± 0.014	0.262CysPro: 0.262 ± 0.017	0.177CysGln: 0.177 ± 0.011	0.195CysArg: 0.195 ± 0.011	0.483CysSer: 0.483 ± 0.018	0.339CysThr: 0.339 ± 0.017	0.369CysVal: 0.369 ± 0.018	0.06CysTrp: 0.06 ± 0.006	0.265CysTyr: 0.265 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.707AspAla: 3.707 ± 0.062	0.356AspCys: 0.356 ± 0.017	3.051AspAsp: 3.051 ± 0.049	4.131AspGlu: 4.131 ± 0.063	3.889AspPhe: 3.889 ± 0.06	3.868AspGly: 3.868 ± 0.063	1.181AspHis: 1.181 ± 0.029	4.354AspIle: 4.354 ± 0.062	3.948AspLys: 3.948 ± 0.063	5.64AspLeu: 5.64 ± 0.061	1.126AspMet: 1.126 ± 0.03	2.942AspAsn: 2.942 ± 0.052	2.042AspPro: 2.042 ± 0.037	1.962AspGln: 1.962 ± 0.038	2.235AspArg: 2.235 ± 0.039	3.285AspSer: 3.285 ± 0.053	2.562AspThr: 2.562 ± 0.043	3.259AspVal: 3.259 ± 0.057	0.872AspTrp: 0.872 ± 0.026	3.105AspTyr: 3.105 ± 0.057	0.0AspXaa: 0.0 ± 0.0
Glu	5.028GluAla: 5.028 ± 0.073	0.32GluCys: 0.32 ± 0.016	4.685GluAsp: 4.685 ± 0.052	6.295GluGlu: 6.295 ± 0.086	3.4GluPhe: 3.4 ± 0.055	4.218GluGly: 4.218 ± 0.055	1.188GluHis: 1.188 ± 0.03	6.368GluIle: 6.368 ± 0.074	6.337GluLys: 6.337 ± 0.089	6.368GluLeu: 6.368 ± 0.075	1.805GluMet: 1.805 ± 0.04	5.69GluAsn: 5.69 ± 0.075	1.724GluPro: 1.724 ± 0.035	2.357GluGln: 2.357 ± 0.042	2.7GluArg: 2.7 ± 0.052	3.593GluSer: 3.593 ± 0.051	3.778GluThr: 3.778 ± 0.045	4.605GluVal: 4.605 ± 0.063	0.725GluTrp: 0.725 ± 0.023	2.744GluTyr: 2.744 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	2.951PheAla: 2.951 ± 0.051	0.403PheCys: 0.403 ± 0.017	3.234PheAsp: 3.234 ± 0.053	3.586PheGlu: 3.586 ± 0.053	2.63PhePhe: 2.63 ± 0.061	3.572PheGly: 3.572 ± 0.067	0.832PheHis: 0.832 ± 0.023	3.767PheIle: 3.767 ± 0.058	3.772PheLys: 3.772 ± 0.058	4.855PheLeu: 4.855 ± 0.072	1.165PheMet: 1.165 ± 0.03	3.22PheAsn: 3.22 ± 0.051	1.785PhePro: 1.785 ± 0.035	1.812PheGln: 1.812 ± 0.033	1.849PheArg: 1.849 ± 0.039	4.293PheSer: 4.293 ± 0.071	2.995PheThr: 2.995 ± 0.043	2.779PheVal: 2.779 ± 0.045	0.652PheTrp: 0.652 ± 0.023	2.336PheTyr: 2.336 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	4.039GlyAla: 4.039 ± 0.069	0.49GlyCys: 0.49 ± 0.018	3.607GlyAsp: 3.607 ± 0.05	4.2GlyGlu: 4.2 ± 0.062	3.568GlyPhe: 3.568 ± 0.054	4.5GlyGly: 4.5 ± 0.081	1.129GlyHis: 1.129 ± 0.029	5.39GlyIle: 5.39 ± 0.061	4.808GlyLys: 4.808 ± 0.067	5.619GlyLeu: 5.619 ± 0.063	1.605GlyMet: 1.605 ± 0.034	3.739GlyAsn: 3.739 ± 0.063	1.326GlyPro: 1.326 ± 0.032	1.866GlyGln: 1.866 ± 0.038	2.223GlyArg: 2.223 ± 0.052	4.053GlySer: 4.053 ± 0.061	3.651GlyThr: 3.651 ± 0.062	4.201GlyVal: 4.201 ± 0.068	0.842GlyTrp: 0.842 ± 0.028	2.915GlyTyr: 2.915 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	0.895HisAla: 0.895 ± 0.028	0.151HisCys: 0.151 ± 0.011	0.833HisAsp: 0.833 ± 0.025	0.988HisGlu: 0.988 ± 0.029	1.127HisPhe: 1.127 ± 0.027	1.063HisGly: 1.063 ± 0.026	0.466HisHis: 0.466 ± 0.018	1.316HisIle: 1.316 ± 0.032	1.128HisLys: 1.128 ± 0.033	1.789HisLeu: 1.789 ± 0.04	0.309HisMet: 0.309 ± 0.016	0.899HisAsn: 0.899 ± 0.025	0.903HisPro: 0.903 ± 0.026	0.807HisGln: 0.807 ± 0.024	0.699HisArg: 0.699 ± 0.022	1.073HisSer: 1.073 ± 0.023	0.855HisThr: 0.855 ± 0.027	0.84HisVal: 0.84 ± 0.023	0.243HisTrp: 0.243 ± 0.016	0.819HisTyr: 0.819 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.42IleAla: 5.42 ± 0.063	0.558IleCys: 0.558 ± 0.023	4.892IleAsp: 4.892 ± 0.053	5.743IleGlu: 5.743 ± 0.071	3.835IlePhe: 3.835 ± 0.057	4.846IleGly: 4.846 ± 0.063	1.247IleHis: 1.247 ± 0.031	5.606IleIle: 5.606 ± 0.078	5.498IleLys: 5.498 ± 0.073	7.191IleLeu: 7.191 ± 0.089	1.314IleMet: 1.314 ± 0.032	4.413IleAsn: 4.413 ± 0.069	3.252IlePro: 3.252 ± 0.05	2.569IleGln: 2.569 ± 0.043	2.599IleArg: 2.599 ± 0.041	5.893IleSer: 5.893 ± 0.073	4.417IleThr: 4.417 ± 0.055	4.158IleVal: 4.158 ± 0.064	0.77IleTrp: 0.77 ± 0.023	2.938IleTyr: 2.938 ± 0.05	0.0IleXaa: 0.0 ± 0.0
Lys	4.814LysAla: 4.814 ± 0.076	0.292LysCys: 0.292 ± 0.014	4.584LysAsp: 4.584 ± 0.073	6.381LysGlu: 6.381 ± 0.095	3.111LysPhe: 3.111 ± 0.048	3.99LysGly: 3.99 ± 0.055	1.257LysHis: 1.257 ± 0.03	6.27LysIle: 6.27 ± 0.075	6.548LysLys: 6.548 ± 0.08	6.694LysLeu: 6.694 ± 0.086	1.941LysMet: 1.941 ± 0.046	5.228LysAsn: 5.228 ± 0.079	2.406LysPro: 2.406 ± 0.049	2.606LysGln: 2.606 ± 0.049	2.897LysArg: 2.897 ± 0.05	4.476LysSer: 4.476 ± 0.063	4.339LysThr: 4.339 ± 0.058	4.341LysVal: 4.341 ± 0.062	0.797LysTrp: 0.797 ± 0.024	2.975LysTyr: 2.975 ± 0.053	0.0LysXaa: 0.0 ± 0.0
Leu	5.883LeuAla: 5.883 ± 0.081	0.657LeuCys: 0.657 ± 0.023	5.391LeuAsp: 5.391 ± 0.071	6.556LeuGlu: 6.556 ± 0.078	4.649LeuPhe: 4.649 ± 0.062	5.737LeuGly: 5.737 ± 0.073	1.54LeuHis: 1.54 ± 0.036	6.736LeuIle: 6.736 ± 0.09	7.953LeuLys: 7.953 ± 0.089	8.161LeuLeu: 8.161 ± 0.104	2.007LeuMet: 2.007 ± 0.046	5.755LeuAsn: 5.755 ± 0.071	3.6LeuPro: 3.6 ± 0.057	3.616LeuGln: 3.616 ± 0.053	3.334LeuArg: 3.334 ± 0.048	6.764LeuSer: 6.764 ± 0.088	4.402LeuThr: 4.402 ± 0.063	5.141LeuVal: 5.141 ± 0.062	0.857LeuTrp: 0.857 ± 0.028	3.205LeuTyr: 3.205 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	1.623MetAla: 1.623 ± 0.035	0.119MetCys: 0.119 ± 0.01	1.176MetAsp: 1.176 ± 0.029	1.474MetGlu: 1.474 ± 0.031	0.848MetPhe: 0.848 ± 0.025	1.408MetGly: 1.408 ± 0.031	0.384MetHis: 0.384 ± 0.02	1.561MetIle: 1.561 ± 0.04	2.071MetLys: 2.071 ± 0.046	2.055MetLeu: 2.055 ± 0.037	0.57MetMet: 0.57 ± 0.026	1.322MetAsn: 1.322 ± 0.032	0.894MetPro: 0.894 ± 0.023	0.906MetGln: 0.906 ± 0.028	0.923MetArg: 0.923 ± 0.026	1.313MetSer: 1.313 ± 0.031	0.993MetThr: 0.993 ± 0.023	1.285MetVal: 1.285 ± 0.032	0.188MetTrp: 0.188 ± 0.011	0.711MetTyr: 0.711 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.748AsnAla: 3.748 ± 0.053	0.368AsnCys: 0.368 ± 0.017	3.208AsnAsp: 3.208 ± 0.052	3.988AsnGlu: 3.988 ± 0.064	3.455AsnPhe: 3.455 ± 0.058	3.908AsnGly: 3.908 ± 0.068	1.024AsnHis: 1.024 ± 0.029	4.798AsnIle: 4.798 ± 0.074	3.984AsnLys: 3.984 ± 0.06	5.655AsnLeu: 5.655 ± 0.075	1.234AsnMet: 1.234 ± 0.029	3.573AsnAsn: 3.573 ± 0.06	2.717AsnPro: 2.717 ± 0.045	2.251AsnGln: 2.251 ± 0.045	2.367AsnArg: 2.367 ± 0.043	4.05AsnSer: 4.05 ± 0.068	3.319AsnThr: 3.319 ± 0.054	3.237AsnVal: 3.237 ± 0.05	0.881AsnTrp: 0.881 ± 0.025	3.044AsnTyr: 3.044 ± 0.057	0.0AsnXaa: 0.0 ± 0.0
Pro	1.98ProAla: 1.98 ± 0.036	0.168ProCys: 0.168 ± 0.012	2.187ProAsp: 2.187 ± 0.044	3.527ProGlu: 3.527 ± 0.045	1.817ProPhe: 1.817 ± 0.038	2.204ProGly: 2.204 ± 0.041	0.584ProHis: 0.584 ± 0.023	2.504ProIle: 2.504 ± 0.047	2.563ProLys: 2.563 ± 0.047	2.9ProLeu: 2.9 ± 0.051	0.699ProMet: 0.699 ± 0.025	2.075ProAsn: 2.075 ± 0.043	0.798ProPro: 0.798 ± 0.03	1.271ProGln: 1.271 ± 0.03	0.988ProArg: 0.988 ± 0.026	2.197ProSer: 2.197 ± 0.038	1.69ProThr: 1.69 ± 0.035	2.526ProVal: 2.526 ± 0.04	0.398ProTrp: 0.398 ± 0.015	1.452ProTyr: 1.452 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	2.049GlnAla: 2.049 ± 0.045	0.147GlnCys: 0.147 ± 0.01	1.966GlnAsp: 1.966 ± 0.039	2.756GlnGlu: 2.756 ± 0.046	1.79GlnPhe: 1.79 ± 0.036	1.797GlnGly: 1.797 ± 0.036	0.621GlnHis: 0.621 ± 0.021	2.632GlnIle: 2.632 ± 0.043	2.946GlnLys: 2.946 ± 0.048	3.72GlnLeu: 3.72 ± 0.056	0.81GlnMet: 0.81 ± 0.025	2.428GlnAsn: 2.428 ± 0.047	1.173GlnPro: 1.173 ± 0.032	1.826GlnGln: 1.826 ± 0.043	1.371GlnArg: 1.371 ± 0.031	2.053GlnSer: 2.053 ± 0.039	1.791GlnThr: 1.791 ± 0.039	1.989GlnVal: 1.989 ± 0.042	0.398GlnTrp: 0.398 ± 0.018	1.38GlnTyr: 1.38 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	2.189ArgAla: 2.189 ± 0.045	0.188ArgCys: 0.188 ± 0.012	1.956ArgAsp: 1.956 ± 0.039	2.566ArgGlu: 2.566 ± 0.041	2.029ArgPhe: 2.029 ± 0.043	2.092ArgGly: 2.092 ± 0.048	0.633ArgHis: 0.633 ± 0.022	2.977ArgIle: 2.977 ± 0.04	3.022ArgLys: 3.022 ± 0.048	3.427ArgLeu: 3.427 ± 0.051	0.877ArgMet: 0.877 ± 0.025	2.351ArgAsn: 2.351 ± 0.041	1.146ArgPro: 1.146 ± 0.03	1.225ArgGln: 1.225 ± 0.03	1.48ArgArg: 1.48 ± 0.035	2.172ArgSer: 2.172 ± 0.043	1.82ArgThr: 1.82 ± 0.037	1.991ArgVal: 1.991 ± 0.04	0.466ArgTrp: 0.466 ± 0.021	1.636ArgTyr: 1.636 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	4.07SerAla: 4.07 ± 0.056	0.616SerCys: 0.616 ± 0.019	3.492SerAsp: 3.492 ± 0.054	4.986SerGlu: 4.986 ± 0.063	3.903SerPhe: 3.903 ± 0.06	4.673SerGly: 4.673 ± 0.058	1.046SerHis: 1.046 ± 0.026	5.136SerIle: 5.136 ± 0.066	4.738SerLys: 4.738 ± 0.061	6.345SerLeu: 6.345 ± 0.076	1.316SerMet: 1.316 ± 0.031	3.632SerAsn: 3.632 ± 0.052	2.139SerPro: 2.139 ± 0.043	2.117SerGln: 2.117 ± 0.044	2.33SerArg: 2.33 ± 0.042	4.375SerSer: 4.375 ± 0.06	3.377SerThr: 3.377 ± 0.058	4.02SerVal: 4.02 ± 0.06	0.821SerTrp: 0.821 ± 0.024	2.869SerTyr: 2.869 ± 0.046	0.0SerXaa: 0.0 ± 0.0
Thr	3.621ThrAla: 3.621 ± 0.057	0.286ThrCys: 0.286 ± 0.015	2.987ThrAsp: 2.987 ± 0.042	3.817ThrGlu: 3.817 ± 0.055	2.529ThrPhe: 2.529 ± 0.045	4.039ThrGly: 4.039 ± 0.064	0.863ThrHis: 0.863 ± 0.026	4.043ThrIle: 4.043 ± 0.059	3.524ThrLys: 3.524 ± 0.056	4.594ThrLeu: 4.594 ± 0.058	0.91ThrMet: 0.91 ± 0.024	2.966ThrAsn: 2.966 ± 0.054	2.313ThrPro: 2.313 ± 0.042	1.74ThrGln: 1.74 ± 0.034	1.744ThrArg: 1.744 ± 0.034	3.761ThrSer: 3.761 ± 0.06	2.981ThrThr: 2.981 ± 0.052	3.03ThrVal: 3.03 ± 0.054	0.506ThrTrp: 0.506 ± 0.021	2.363ThrTyr: 2.363 ± 0.046	0.0ThrXaa: 0.0 ± 0.0
Val	3.919ValAla: 3.919 ± 0.067	0.415ValCys: 0.415 ± 0.018	3.417ValAsp: 3.417 ± 0.05	4.024ValGlu: 4.024 ± 0.062	3.179ValPhe: 3.179 ± 0.051	3.536ValGly: 3.536 ± 0.054	0.96ValHis: 0.96 ± 0.026	4.57ValIle: 4.57 ± 0.061	4.091ValLys: 4.091 ± 0.06	5.533ValLeu: 5.533 ± 0.066	1.319ValMet: 1.319 ± 0.033	3.398ValAsn: 3.398 ± 0.054	2.132ValPro: 2.132 ± 0.042	1.759ValGln: 1.759 ± 0.034	1.941ValArg: 1.941 ± 0.042	4.252ValSer: 4.252 ± 0.055	3.056ValThr: 3.056 ± 0.05	3.638ValVal: 3.638 ± 0.068	0.624ValTrp: 0.624 ± 0.02	2.402ValTyr: 2.402 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	0.688TrpAla: 0.688 ± 0.023	0.093TrpCys: 0.093 ± 0.008	0.724TrpAsp: 0.724 ± 0.025	0.804TrpGlu: 0.804 ± 0.028	0.588TrpPhe: 0.588 ± 0.022	0.734TrpGly: 0.734 ± 0.022	0.229TrpHis: 0.229 ± 0.014	0.805TrpIle: 0.805 ± 0.027	0.823TrpLys: 0.823 ± 0.027	1.037TrpLeu: 1.037 ± 0.027	0.327TrpMet: 0.327 ± 0.014	0.769TrpAsn: 0.769 ± 0.023	0.324TrpPro: 0.324 ± 0.015	0.489TrpGln: 0.489 ± 0.019	0.469TrpArg: 0.469 ± 0.021	0.692TrpSer: 0.692 ± 0.023	0.567TrpThr: 0.567 ± 0.022	0.633TrpVal: 0.633 ± 0.023	0.182TrpTrp: 0.182 ± 0.012	0.496TrpTyr: 0.496 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.586TyrAla: 2.586 ± 0.047	0.283TyrCys: 0.283 ± 0.014	2.497TyrAsp: 2.497 ± 0.042	2.505TyrGlu: 2.505 ± 0.044	2.588TyrPhe: 2.588 ± 0.05	2.785TyrGly: 2.785 ± 0.053	0.821TyrHis: 0.821 ± 0.027	2.615TyrIle: 2.615 ± 0.042	2.998TyrLys: 2.998 ± 0.057	3.938TyrLeu: 3.938 ± 0.056	0.777TyrMet: 0.777 ± 0.023	2.614TyrAsn: 2.614 ± 0.056	1.692TyrPro: 1.692 ± 0.037	1.805TyrGln: 1.805 ± 0.035	1.823TyrArg: 1.823 ± 0.038	2.891TyrSer: 2.891 ± 0.054	2.373TyrThr: 2.373 ± 0.046	2.104TyrVal: 2.104 ± 0.044	0.526TyrTrp: 0.526 ± 0.02	1.965TyrTyr: 1.965 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4100 proteins (1425727 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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