Amino acid dipepetide frequency for Ribes americanum virus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.16AlaAla: 4.16 ± 1.446
0.416AlaCys: 0.416 ± 0.207
5.408AlaAsp: 5.408 ± 2.033
2.912AlaGlu: 2.912 ± 1.041
4.16AlaPhe: 4.16 ± 2.796
4.576AlaGly: 4.576 ± 2.279
0.416AlaHis: 0.416 ± 0.207
2.08AlaIle: 2.08 ± 1.222
5.408AlaLys: 5.408 ± 1.372
7.072AlaLeu: 7.072 ± 3.797
0.0AlaMet: 0.0 ± 0.0
2.912AlaAsn: 2.912 ± 0.888
0.416AlaPro: 0.416 ± 0.207
0.832AlaGln: 0.832 ± 0.659
3.328AlaArg: 3.328 ± 2.713
5.408AlaSer: 5.408 ± 3.597
1.248AlaThr: 1.248 ± 1.176
3.744AlaVal: 3.744 ± 1.237
0.832AlaTrp: 0.832 ± 0.659
0.832AlaTyr: 0.832 ± 1.354
0.0AlaXaa: 0.0 ± 0.0
Cys
1.248CysAla: 1.248 ± 1.438
0.832CysCys: 0.832 ± 0.659
0.0CysAsp: 0.0 ± 0.0
0.416CysGlu: 0.416 ± 0.207
0.416CysPhe: 0.416 ± 0.207
2.08CysGly: 2.08 ± 0.86
0.416CysHis: 0.416 ± 0.788
2.08CysIle: 2.08 ± 0.624
3.328CysLys: 3.328 ± 1.128
2.496CysLeu: 2.496 ± 1.278
0.416CysMet: 0.416 ± 0.207
0.832CysAsn: 0.832 ± 1.549
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.248CysArg: 1.248 ± 0.621
0.832CysSer: 0.832 ± 0.659
2.496CysThr: 2.496 ± 1.155
2.08CysVal: 2.08 ± 3.459
0.0CysTrp: 0.0 ± 0.0
2.08CysTyr: 2.08 ± 1.918
0.0CysXaa: 0.0 ± 0.0
Asp
4.16AspAla: 4.16 ± 0.794
0.832AspCys: 0.832 ± 0.414
2.08AspAsp: 2.08 ± 1.036
4.16AspGlu: 4.16 ± 2.072
6.24AspPhe: 6.24 ± 1.302
2.912AspGly: 2.912 ± 2.76
1.664AspHis: 1.664 ± 0.829
1.664AspIle: 1.664 ± 0.564
2.08AspLys: 2.08 ± 1.814
7.903AspLeu: 7.903 ± 2.675
3.744AspMet: 3.744 ± 1.237
2.08AspAsn: 2.08 ± 1.036
3.328AspPro: 3.328 ± 1.657
0.416AspGln: 0.416 ± 0.788
4.16AspArg: 4.16 ± 1.72
7.488AspSer: 7.488 ± 2.651
1.664AspThr: 1.664 ± 1.318
4.16AspVal: 4.16 ± 1.541
0.416AspTrp: 0.416 ± 0.207
3.744AspTyr: 3.744 ± 1.864
0.0AspXaa: 0.0 ± 0.0
Glu
5.824GluAla: 5.824 ± 2.211
0.416GluCys: 0.416 ± 0.207
3.328GluAsp: 3.328 ± 1.056
4.16GluGlu: 4.16 ± 1.694
2.496GluPhe: 2.496 ± 0.935
5.824GluGly: 5.824 ± 1.445
1.248GluHis: 1.248 ± 0.621
4.576GluIle: 4.576 ± 4.969
2.912GluLys: 2.912 ± 1.123
4.992GluLeu: 4.992 ± 1.477
2.496GluMet: 2.496 ± 1.155
4.16GluAsn: 4.16 ± 2.58
0.416GluPro: 0.416 ± 0.788
1.664GluGln: 1.664 ± 0.829
4.992GluArg: 4.992 ± 1.478
4.16GluSer: 4.16 ± 1.247
2.912GluThr: 2.912 ± 0.888
6.24GluVal: 6.24 ± 1.871
0.0GluTrp: 0.0 ± 0.0
0.416GluTyr: 0.416 ± 1.059
0.0GluXaa: 0.0 ± 0.0
Phe
2.496PheAla: 2.496 ± 1.243
2.912PheCys: 2.912 ± 1.634
3.744PheAsp: 3.744 ± 1.602
5.824PheGlu: 5.824 ± 1.445
2.496PhePhe: 2.496 ± 0.739
2.496PheGly: 2.496 ± 0.739
1.664PheHis: 1.664 ± 0.564
2.08PheIle: 2.08 ± 1.398
3.744PheLys: 3.744 ± 1.831
5.824PheLeu: 5.824 ± 1.092
2.08PheMet: 2.08 ± 1.537
2.912PheAsn: 2.912 ± 3.112
3.328PhePro: 3.328 ± 1.657
1.664PheGln: 1.664 ± 0.846
1.664PheArg: 1.664 ± 0.564
3.744PheSer: 3.744 ± 1.325
2.08PheThr: 2.08 ± 0.624
4.16PheVal: 4.16 ± 2.031
0.832PheTrp: 0.832 ± 0.659
2.496PheTyr: 2.496 ± 0.935
0.0PheXaa: 0.0 ± 0.0
Gly
2.496GlyAla: 2.496 ± 0.739
1.664GlyCys: 1.664 ± 0.564
5.824GlyAsp: 5.824 ± 2.081
2.496GlyGlu: 2.496 ± 1.155
2.496GlyPhe: 2.496 ± 1.243
3.744GlyGly: 3.744 ± 2.625
2.496GlyHis: 2.496 ± 1.243
3.328GlyIle: 3.328 ± 1.966
3.744GlyLys: 3.744 ± 0.694
7.072GlyLeu: 7.072 ± 1.435
0.832GlyMet: 0.832 ± 0.414
1.248GlyAsn: 1.248 ± 0.621
2.496GlyPro: 2.496 ± 1.243
2.08GlyGln: 2.08 ± 2.948
3.744GlyArg: 3.744 ± 1.171
4.992GlySer: 4.992 ± 1.396
2.496GlyThr: 2.496 ± 0.935
5.408GlyVal: 5.408 ± 2.011
1.248GlyTrp: 1.248 ± 0.621
2.08GlyTyr: 2.08 ± 0.86
0.0GlyXaa: 0.0 ± 0.0
His
0.832HisAla: 0.832 ± 0.414
0.832HisCys: 0.832 ± 0.659
0.832HisAsp: 0.832 ± 0.414
1.248HisGlu: 1.248 ± 0.577
0.832HisPhe: 0.832 ± 2.119
2.08HisGly: 2.08 ± 0.624
1.248HisHis: 1.248 ± 0.621
0.832HisIle: 0.832 ± 0.414
1.248HisLys: 1.248 ± 0.621
2.496HisLeu: 2.496 ± 0.739
0.832HisMet: 0.832 ± 0.414
0.0HisAsn: 0.0 ± 0.0
0.416HisPro: 0.416 ± 0.207
0.416HisGln: 0.416 ± 0.207
1.248HisArg: 1.248 ± 0.621
2.912HisSer: 2.912 ± 0.888
0.0HisThr: 0.0 ± 0.0
0.832HisVal: 0.832 ± 0.659
0.0HisTrp: 0.0 ± 0.0
0.416HisTyr: 0.416 ± 0.207
0.0HisXaa: 0.0 ± 0.0
Ile
2.496IleAla: 2.496 ± 2.238
1.248IleCys: 1.248 ± 1.663
1.664IleAsp: 1.664 ± 2.146
4.992IleGlu: 4.992 ± 2.31
2.496IlePhe: 2.496 ± 0.739
4.576IleGly: 4.576 ± 1.856
0.832IleHis: 0.832 ± 0.414
1.248IleIle: 1.248 ± 2.179
2.912IleLys: 2.912 ± 2.576
8.735IleLeu: 8.735 ± 1.745
2.08IleMet: 2.08 ± 1.075
2.08IleAsn: 2.08 ± 0.624
1.664IlePro: 1.664 ± 0.564
0.832IleGln: 0.832 ± 0.414
2.496IleArg: 2.496 ± 0.739
4.576IleSer: 4.576 ± 1.617
0.0IleThr: 0.0 ± 0.0
1.664IleVal: 1.664 ± 1.009
0.832IleTrp: 0.832 ± 0.414
3.328IleTyr: 3.328 ± 2.997
0.0IleXaa: 0.0 ± 0.0
Lys
4.576LysAla: 4.576 ± 1.59
2.08LysCys: 2.08 ± 0.624
5.408LysAsp: 5.408 ± 1.416
3.744LysGlu: 3.744 ± 1.171
2.08LysPhe: 2.08 ± 1.036
4.576LysGly: 4.576 ± 0.931
0.832LysHis: 0.832 ± 0.659
4.16LysIle: 4.16 ± 2.517
4.992LysLys: 4.992 ± 3.256
7.488LysLeu: 7.488 ± 2.501
3.744LysMet: 3.744 ± 1.171
3.328LysAsn: 3.328 ± 1.056
0.416LysPro: 0.416 ± 0.207
0.0LysGln: 0.0 ± 0.0
5.408LysArg: 5.408 ± 1.906
2.496LysSer: 2.496 ± 3.889
3.328LysThr: 3.328 ± 1.173
4.576LysVal: 4.576 ± 1.681
0.832LysTrp: 0.832 ± 0.414
0.832LysTyr: 0.832 ± 0.949
0.0LysXaa: 0.0 ± 0.0
Leu
4.576LeuAla: 4.576 ± 3.032
2.08LeuCys: 2.08 ± 2.094
7.903LeuAsp: 7.903 ± 2.411
5.824LeuGlu: 5.824 ± 1.79
7.072LeuPhe: 7.072 ± 2.418
5.824LeuGly: 5.824 ± 1.775
2.08LeuHis: 2.08 ± 0.868
6.656LeuIle: 6.656 ± 3.114
9.567LeuLys: 9.567 ± 1.905
12.479LeuLeu: 12.479 ± 4.907
2.496LeuMet: 2.496 ± 1.243
2.496LeuAsn: 2.496 ± 1.278
3.744LeuPro: 3.744 ± 0.997
2.496LeuGln: 2.496 ± 0.739
8.319LeuArg: 8.319 ± 2.506
5.824LeuSer: 5.824 ± 1.546
5.824LeuThr: 5.824 ± 2.657
10.399LeuVal: 10.399 ± 3.444
0.416LeuTrp: 0.416 ± 0.788
2.912LeuTyr: 2.912 ± 3.054
0.0LeuXaa: 0.0 ± 0.0
Met
4.16MetAla: 4.16 ± 0.794
1.248MetCys: 1.248 ± 1.471
2.496MetAsp: 2.496 ± 0.739
1.664MetGlu: 1.664 ± 1.318
1.664MetPhe: 1.664 ± 0.829
1.664MetGly: 1.664 ± 0.829
0.0MetHis: 0.0 ± 0.0
1.248MetIle: 1.248 ± 0.621
1.664MetLys: 1.664 ± 0.564
2.496MetLeu: 2.496 ± 0.935
0.0MetMet: 0.0 ± 0.0
0.832MetAsn: 0.832 ± 2.038
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
2.912MetArg: 2.912 ± 1.123
2.08MetSer: 2.08 ± 1.222
2.08MetThr: 2.08 ± 0.624
2.912MetVal: 2.912 ± 0.888
0.416MetTrp: 0.416 ± 0.207
1.664MetTyr: 1.664 ± 0.846
0.0MetXaa: 0.0 ± 0.0
Asn
0.832AsnAla: 0.832 ± 0.949
1.248AsnCys: 1.248 ± 0.875
3.328AsnAsp: 3.328 ± 1.657
2.912AsnGlu: 2.912 ± 2.76
3.328AsnPhe: 3.328 ± 2.99
2.496AsnGly: 2.496 ± 1.416
1.664AsnHis: 1.664 ± 0.564
1.248AsnIle: 1.248 ± 0.875
1.664AsnLys: 1.664 ± 0.846
2.496AsnLeu: 2.496 ± 1.278
1.664AsnMet: 1.664 ± 0.846
0.832AsnAsn: 0.832 ± 0.949
1.248AsnPro: 1.248 ± 0.577
0.832AsnGln: 0.832 ± 0.414
2.496AsnArg: 2.496 ± 1.243
5.408AsnSer: 5.408 ± 2.248
0.416AsnThr: 0.416 ± 0.207
2.912AsnVal: 2.912 ± 1.776
1.664AsnTrp: 1.664 ± 0.829
0.416AsnTyr: 0.416 ± 0.207
0.0AsnXaa: 0.0 ± 0.0
Pro
2.08ProAla: 2.08 ± 1.036
0.0ProCys: 0.0 ± 0.0
2.08ProAsp: 2.08 ± 1.036
2.496ProGlu: 2.496 ± 0.739
2.496ProPhe: 2.496 ± 0.739
0.832ProGly: 0.832 ± 0.414
0.0ProHis: 0.0 ± 0.0
4.16ProIle: 4.16 ± 1.425
1.248ProLys: 1.248 ± 0.577
4.16ProLeu: 4.16 ± 1.694
0.832ProMet: 0.832 ± 0.414
1.664ProAsn: 1.664 ± 0.829
0.416ProPro: 0.416 ± 0.207
0.416ProGln: 0.416 ± 0.207
2.08ProArg: 2.08 ± 1.036
3.744ProSer: 3.744 ± 1.864
0.832ProThr: 0.832 ± 0.414
1.248ProVal: 1.248 ± 0.577
0.416ProTrp: 0.416 ± 0.207
1.664ProTyr: 1.664 ± 0.829
0.0ProXaa: 0.0 ± 0.0
Gln
0.416GlnAla: 0.416 ± 0.207
0.0GlnCys: 0.0 ± 0.0
1.248GlnAsp: 1.248 ± 0.577
0.832GlnGlu: 0.832 ± 1.354
0.832GlnPhe: 0.832 ± 0.414
1.248GlnGly: 1.248 ± 0.875
0.0GlnHis: 0.0 ± 0.0
2.08GlnIle: 2.08 ± 0.868
1.248GlnLys: 1.248 ± 0.621
0.832GlnLeu: 0.832 ± 0.414
1.664GlnMet: 1.664 ± 0.829
0.416GlnAsn: 0.416 ± 1.059
1.248GlnPro: 1.248 ± 0.577
0.0GlnGln: 0.0 ± 0.0
2.08GlnArg: 2.08 ± 2.529
0.832GlnSer: 0.832 ± 0.414
1.664GlnThr: 1.664 ± 0.846
0.832GlnVal: 0.832 ± 0.949
0.416GlnTrp: 0.416 ± 0.788
1.248GlnTyr: 1.248 ± 0.621
0.0GlnXaa: 0.0 ± 0.0
Arg
2.08ArgAla: 2.08 ± 0.868
0.416ArgCys: 0.416 ± 0.207
4.16ArgAsp: 4.16 ± 1.446
3.744ArgGlu: 3.744 ± 1.732
3.328ArgPhe: 3.328 ± 1.173
2.08ArgGly: 2.08 ± 0.86
2.496ArgHis: 2.496 ± 0.739
2.912ArgIle: 2.912 ± 0.888
3.744ArgLys: 3.744 ± 1.864
10.815ArgLeu: 10.815 ± 2.605
1.664ArgMet: 1.664 ± 1.975
3.744ArgAsn: 3.744 ± 1.513
2.496ArgPro: 2.496 ± 0.739
2.912ArgGln: 2.912 ± 2.124
5.408ArgArg: 5.408 ± 2.107
4.576ArgSer: 4.576 ± 1.974
3.744ArgThr: 3.744 ± 2.717
2.496ArgVal: 2.496 ± 0.739
0.832ArgTrp: 0.832 ± 0.414
2.496ArgTyr: 2.496 ± 0.935
0.0ArgXaa: 0.0 ± 0.0
Ser
5.824SerAla: 5.824 ± 2.122
2.912SerCys: 2.912 ± 1.123
4.16SerAsp: 4.16 ± 1.735
4.992SerGlu: 4.992 ± 1.813
8.319SerPhe: 8.319 ± 3.309
6.24SerGly: 6.24 ± 2.416
0.832SerHis: 0.832 ± 0.414
3.328SerIle: 3.328 ± 1.056
7.072SerLys: 7.072 ± 2.072
9.151SerLeu: 9.151 ± 2.007
2.08SerMet: 2.08 ± 0.624
1.664SerAsn: 1.664 ± 0.829
3.744SerPro: 3.744 ± 1.864
1.664SerGln: 1.664 ± 0.846
2.08SerArg: 2.08 ± 1.387
7.488SerSer: 7.488 ± 4.612
3.328SerThr: 3.328 ± 1.116
6.24SerVal: 6.24 ± 2.04
1.248SerTrp: 1.248 ± 0.621
2.912SerTyr: 2.912 ± 2.115
0.0SerXaa: 0.0 ± 0.0
Thr
1.664ThrAla: 1.664 ± 0.564
0.416ThrCys: 0.416 ± 0.788
2.496ThrAsp: 2.496 ± 2.292
2.912ThrGlu: 2.912 ± 1.717
2.08ThrPhe: 2.08 ± 1.036
2.08ThrGly: 2.08 ± 1.222
0.832ThrHis: 0.832 ± 0.414
1.664ThrIle: 1.664 ± 1.517
3.328ThrLys: 3.328 ± 1.056
3.328ThrLeu: 3.328 ± 1.128
0.416ThrMet: 0.416 ± 0.207
2.08ThrAsn: 2.08 ± 0.624
1.664ThrPro: 1.664 ± 0.829
0.416ThrGln: 0.416 ± 0.207
3.328ThrArg: 3.328 ± 1.605
2.912ThrSer: 2.912 ± 1.258
0.832ThrThr: 0.832 ± 0.659
4.576ThrVal: 4.576 ± 1.351
0.0ThrTrp: 0.0 ± 0.0
1.664ThrTyr: 1.664 ± 1.42
0.0ThrXaa: 0.0 ± 0.0
Val
4.576ValAla: 4.576 ± 4.23
1.248ValCys: 1.248 ± 2.27
5.824ValAsp: 5.824 ± 1.445
4.992ValGlu: 4.992 ± 1.693
4.16ValPhe: 4.16 ± 1.699
4.16ValGly: 4.16 ± 1.699
0.416ValHis: 0.416 ± 0.207
3.328ValIle: 3.328 ± 1.056
3.328ValLys: 3.328 ± 1.128
5.824ValLeu: 5.824 ± 4.342
3.328ValMet: 3.328 ± 1.517
3.744ValAsn: 3.744 ± 1.237
3.744ValPro: 3.744 ± 1.237
1.248ValGln: 1.248 ± 0.621
4.16ValArg: 4.16 ± 2.072
9.151ValSer: 9.151 ± 2.063
0.832ValThr: 0.832 ± 0.659
4.992ValVal: 4.992 ± 2.486
0.416ValTrp: 0.416 ± 0.207
1.248ValTyr: 1.248 ± 0.621
0.0ValXaa: 0.0 ± 0.0
Trp
0.416TrpAla: 0.416 ± 0.207
0.416TrpCys: 0.416 ± 0.207
0.416TrpAsp: 0.416 ± 0.207
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.416TrpIle: 0.416 ± 0.207
0.832TrpLys: 0.832 ± 0.659
1.248TrpLeu: 1.248 ± 0.577
0.416TrpMet: 0.416 ± 0.207
0.416TrpAsn: 0.416 ± 0.788
0.416TrpPro: 0.416 ± 0.207
0.0TrpGln: 0.0 ± 0.0
1.664TrpArg: 1.664 ± 0.564
2.08TrpSer: 2.08 ± 1.036
1.248TrpThr: 1.248 ± 0.621
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.832TrpTyr: 0.832 ± 0.414
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.248TyrAla: 1.248 ± 0.621
2.08TyrCys: 2.08 ± 1.387
2.496TyrAsp: 2.496 ± 1.407
2.912TyrGlu: 2.912 ± 1.45
1.248TyrPhe: 1.248 ± 0.577
2.496TyrGly: 2.496 ± 1.75
0.416TyrHis: 0.416 ± 0.788
2.08TyrIle: 2.08 ± 3.37
0.832TyrLys: 0.832 ± 0.414
2.08TyrLeu: 2.08 ± 1.906
0.0TyrMet: 0.0 ± 0.0
1.664TyrAsn: 1.664 ± 3.058
1.664TyrPro: 1.664 ± 0.829
1.248TyrGln: 1.248 ± 0.875
3.328TyrArg: 3.328 ± 1.951
4.576TyrSer: 4.576 ± 1.146
1.664TyrThr: 1.664 ± 0.829
1.248TyrVal: 1.248 ± 0.621
0.0TyrTrp: 0.0 ± 0.0
0.832TyrTyr: 0.832 ± 0.414
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2405 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski