Amino acid dipepetide frequency for Antricoccus suffuscus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.379AlaAla: 17.379 ± 0.184	0.944AlaCys: 0.944 ± 0.026	8.057AlaAsp: 8.057 ± 0.094	6.753AlaGlu: 6.753 ± 0.081	3.326AlaPhe: 3.326 ± 0.049	11.003AlaGly: 11.003 ± 0.098	2.522AlaHis: 2.522 ± 0.04	6.215AlaIle: 6.215 ± 0.071	3.76AlaLys: 3.76 ± 0.067	12.25AlaLeu: 12.25 ± 0.11	2.95AlaMet: 2.95 ± 0.043	2.571AlaAsn: 2.571 ± 0.044	5.698AlaPro: 5.698 ± 0.076	4.161AlaGln: 4.161 ± 0.066	7.996AlaArg: 7.996 ± 0.074	6.923AlaSer: 6.923 ± 0.078	7.32AlaThr: 7.32 ± 0.075	10.352AlaVal: 10.352 ± 0.098	1.44AlaTrp: 1.44 ± 0.034	2.693AlaTyr: 2.693 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.98CysAla: 0.98 ± 0.029	0.082CysCys: 0.082 ± 0.008	0.526CysAsp: 0.526 ± 0.02	0.391CysGlu: 0.391 ± 0.017	0.216CysPhe: 0.216 ± 0.012	0.894CysGly: 0.894 ± 0.025	0.192CysHis: 0.192 ± 0.01	0.338CysIle: 0.338 ± 0.014	0.171CysLys: 0.171 ± 0.012	0.649CysLeu: 0.649 ± 0.022	0.136CysMet: 0.136 ± 0.01	0.159CysAsn: 0.159 ± 0.01	0.386CysPro: 0.386 ± 0.018	0.2CysGln: 0.2 ± 0.012	0.494CysArg: 0.494 ± 0.019	0.46CysSer: 0.46 ± 0.018	0.505CysThr: 0.505 ± 0.02	0.624CysVal: 0.624 ± 0.021	0.092CysTrp: 0.092 ± 0.009	0.183CysTyr: 0.183 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.557AspAla: 7.557 ± 0.083	0.415AspCys: 0.415 ± 0.016	4.179AspAsp: 4.179 ± 0.068	4.245AspGlu: 4.245 ± 0.068	1.75AspPhe: 1.75 ± 0.03	5.941AspGly: 5.941 ± 0.065	1.346AspHis: 1.346 ± 0.032	2.839AspIle: 2.839 ± 0.044	1.794AspLys: 1.794 ± 0.035	6.468AspLeu: 6.468 ± 0.066	1.09AspMet: 1.09 ± 0.026	1.351AspAsn: 1.351 ± 0.033	4.264AspPro: 4.264 ± 0.059	1.92AspGln: 1.92 ± 0.037	4.545AspArg: 4.545 ± 0.065	3.177AspSer: 3.177 ± 0.048	3.099AspThr: 3.099 ± 0.055	5.483AspVal: 5.483 ± 0.06	0.881AspTrp: 0.881 ± 0.026	1.393AspTyr: 1.393 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	5.972GluAla: 5.972 ± 0.071	0.37GluCys: 0.37 ± 0.018	2.737GluAsp: 2.737 ± 0.049	2.627GluGlu: 2.627 ± 0.051	1.683GluPhe: 1.683 ± 0.035	3.447GluGly: 3.447 ± 0.056	1.389GluHis: 1.389 ± 0.032	2.901GluIle: 2.901 ± 0.052	1.577GluLys: 1.577 ± 0.038	5.882GluLeu: 5.882 ± 0.083	1.1GluMet: 1.1 ± 0.033	1.06GluAsn: 1.06 ± 0.027	2.754GluPro: 2.754 ± 0.053	2.21GluGln: 2.21 ± 0.044	4.415GluArg: 4.415 ± 0.068	3.257GluSer: 3.257 ± 0.045	2.77GluThr: 2.77 ± 0.049	4.441GluVal: 4.441 ± 0.065	0.745GluTrp: 0.745 ± 0.026	1.192GluTyr: 1.192 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	3.883PheAla: 3.883 ± 0.052	0.3PheCys: 0.3 ± 0.013	2.268PheAsp: 2.268 ± 0.045	1.593PheGlu: 1.593 ± 0.035	0.943PhePhe: 0.943 ± 0.027	3.358PheGly: 3.358 ± 0.051	0.578PheHis: 0.578 ± 0.02	1.231PheIle: 1.231 ± 0.028	0.657PheLys: 0.657 ± 0.026	2.513PheLeu: 2.513 ± 0.045	0.538PheMet: 0.538 ± 0.021	0.787PheAsn: 0.787 ± 0.024	1.357PhePro: 1.357 ± 0.036	0.684PheGln: 0.684 ± 0.024	1.578PheArg: 1.578 ± 0.033	1.756PheSer: 1.756 ± 0.036	1.884PheThr: 1.884 ± 0.035	2.559PheVal: 2.559 ± 0.045	0.441PheTrp: 0.441 ± 0.02	0.644PheTyr: 0.644 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	10.055GlyAla: 10.055 ± 0.102	0.793GlyCys: 0.793 ± 0.024	4.972GlyAsp: 4.972 ± 0.06	4.341GlyGlu: 4.341 ± 0.062	3.08GlyPhe: 3.08 ± 0.051	7.666GlyGly: 7.666 ± 0.103	1.881GlyHis: 1.881 ± 0.042	4.631GlyIle: 4.631 ± 0.059	2.969GlyLys: 2.969 ± 0.051	8.746GlyLeu: 8.746 ± 0.09	2.176GlyMet: 2.176 ± 0.037	2.104GlyAsn: 2.104 ± 0.046	4.054GlyPro: 4.054 ± 0.058	2.832GlyGln: 2.832 ± 0.049	5.783GlyArg: 5.783 ± 0.069	5.509GlySer: 5.509 ± 0.071	5.44GlyThr: 5.44 ± 0.072	7.484GlyVal: 7.484 ± 0.08	1.524GlyTrp: 1.524 ± 0.037	2.419GlyTyr: 2.419 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	2.358HisAla: 2.358 ± 0.04	0.167HisCys: 0.167 ± 0.012	1.393HisAsp: 1.393 ± 0.03	1.15HisGlu: 1.15 ± 0.025	0.639HisPhe: 0.639 ± 0.019	1.936HisGly: 1.936 ± 0.041	0.586HisHis: 0.586 ± 0.02	0.904HisIle: 0.904 ± 0.025	0.448HisLys: 0.448 ± 0.017	2.148HisLeu: 2.148 ± 0.041	0.363HisMet: 0.363 ± 0.018	0.483HisAsn: 0.483 ± 0.02	1.49HisPro: 1.49 ± 0.031	0.651HisGln: 0.651 ± 0.022	1.59HisArg: 1.59 ± 0.033	1.096HisSer: 1.096 ± 0.031	1.138HisThr: 1.138 ± 0.032	1.685HisVal: 1.685 ± 0.033	0.313HisTrp: 0.313 ± 0.015	0.487HisTyr: 0.487 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	7.281IleAla: 7.281 ± 0.078	0.45IleCys: 0.45 ± 0.019	3.738IleAsp: 3.738 ± 0.049	3.016IleGlu: 3.016 ± 0.052	1.353IlePhe: 1.353 ± 0.037	5.193IleGly: 5.193 ± 0.063	0.806IleHis: 0.806 ± 0.023	2.045IleIle: 2.045 ± 0.039	1.235IleLys: 1.235 ± 0.031	3.703IleLeu: 3.703 ± 0.054	0.779IleMet: 0.779 ± 0.023	1.346IleAsn: 1.346 ± 0.031	2.381IlePro: 2.381 ± 0.041	1.072IleGln: 1.072 ± 0.027	2.721IleArg: 2.721 ± 0.049	2.81IleSer: 2.81 ± 0.041	3.027IleThr: 3.027 ± 0.048	4.583IleVal: 4.583 ± 0.06	0.526IleTrp: 0.526 ± 0.019	0.993IleTyr: 0.993 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	3.231LysAla: 3.231 ± 0.052	0.164LysCys: 0.164 ± 0.011	1.672LysAsp: 1.672 ± 0.041	1.317LysGlu: 1.317 ± 0.035	0.842LysPhe: 0.842 ± 0.026	1.967LysGly: 1.967 ± 0.045	0.592LysHis: 0.592 ± 0.02	1.52LysIle: 1.52 ± 0.041	1.209LysLys: 1.209 ± 0.042	2.541LysLeu: 2.541 ± 0.046	0.731LysMet: 0.731 ± 0.025	0.681LysAsn: 0.681 ± 0.022	1.636LysPro: 1.636 ± 0.033	0.923LysGln: 0.923 ± 0.027	1.795LysArg: 1.795 ± 0.032	1.943LysSer: 1.943 ± 0.037	1.721LysThr: 1.721 ± 0.041	2.398LysVal: 2.398 ± 0.047	0.4LysTrp: 0.4 ± 0.015	0.734LysTyr: 0.734 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	12.968LeuAla: 12.968 ± 0.112	0.827LeuCys: 0.827 ± 0.024	6.437LeuAsp: 6.437 ± 0.072	4.618LeuGlu: 4.618 ± 0.074	2.522LeuPhe: 2.522 ± 0.049	8.755LeuGly: 8.755 ± 0.094	1.993LeuHis: 1.993 ± 0.04	4.763LeuIle: 4.763 ± 0.064	2.316LeuLys: 2.316 ± 0.045	9.333LeuLeu: 9.333 ± 0.114	1.901LeuMet: 1.901 ± 0.039	2.059LeuAsn: 2.059 ± 0.038	5.157LeuPro: 5.157 ± 0.063	2.628LeuGln: 2.628 ± 0.046	6.866LeuArg: 6.866 ± 0.076	5.922LeuSer: 5.922 ± 0.068	6.235LeuThr: 6.235 ± 0.069	8.25LeuVal: 8.25 ± 0.078	1.055LeuTrp: 1.055 ± 0.029	1.752LeuTyr: 1.752 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	2.425MetAla: 2.425 ± 0.037	0.201MetCys: 0.201 ± 0.012	0.99MetAsp: 0.99 ± 0.028	0.73MetGlu: 0.73 ± 0.026	0.632MetPhe: 0.632 ± 0.02	1.524MetGly: 1.524 ± 0.035	0.463MetHis: 0.463 ± 0.017	1.096MetIle: 1.096 ± 0.028	0.575MetLys: 0.575 ± 0.018	2.163MetLeu: 2.163 ± 0.043	0.461MetMet: 0.461 ± 0.017	0.545MetAsn: 0.545 ± 0.018	1.312MetPro: 1.312 ± 0.03	0.686MetGln: 0.686 ± 0.022	1.631MetArg: 1.631 ± 0.033	1.855MetSer: 1.855 ± 0.038	1.962MetThr: 1.962 ± 0.039	1.506MetVal: 1.506 ± 0.03	0.26MetTrp: 0.26 ± 0.014	0.448MetTyr: 0.448 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	2.81AsnAla: 2.81 ± 0.048	0.173AsnCys: 0.173 ± 0.011	1.424AsnAsp: 1.424 ± 0.03	1.126AsnGlu: 1.126 ± 0.031	0.693AsnPhe: 0.693 ± 0.023	2.213AsnGly: 2.213 ± 0.041	0.449AsnHis: 0.449 ± 0.017	1.012AsnIle: 1.012 ± 0.028	0.642AsnLys: 0.642 ± 0.021	2.123AsnLeu: 2.123 ± 0.038	0.441AsnMet: 0.441 ± 0.02	0.644AsnAsn: 0.644 ± 0.034	1.788AsnPro: 1.788 ± 0.037	0.708AsnGln: 0.708 ± 0.043	1.435AsnArg: 1.435 ± 0.036	1.298AsnSer: 1.298 ± 0.032	1.201AsnThr: 1.201 ± 0.029	1.876AsnVal: 1.876 ± 0.038	0.315AsnTrp: 0.315 ± 0.014	0.57AsnTyr: 0.57 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	6.47ProAla: 6.47 ± 0.07	0.272ProCys: 0.272 ± 0.016	4.227ProAsp: 4.227 ± 0.062	3.307ProGlu: 3.307 ± 0.052	1.391ProPhe: 1.391 ± 0.035	4.975ProGly: 4.975 ± 0.07	1.187ProHis: 1.187 ± 0.031	2.454ProIle: 2.454 ± 0.047	1.651ProLys: 1.651 ± 0.036	4.415ProLeu: 4.415 ± 0.054	1.24ProMet: 1.24 ± 0.032	1.278ProAsn: 1.278 ± 0.037	2.764ProPro: 2.764 ± 0.067	1.755ProGln: 1.755 ± 0.039	3.145ProArg: 3.145 ± 0.058	3.382ProSer: 3.382 ± 0.058	3.552ProThr: 3.552 ± 0.054	4.293ProVal: 4.293 ± 0.059	0.746ProTrp: 0.746 ± 0.025	1.23ProTyr: 1.23 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	3.447GlnAla: 3.447 ± 0.05	0.19GlnCys: 0.19 ± 0.012	1.402GlnAsp: 1.402 ± 0.033	1.199GlnGlu: 1.199 ± 0.027	0.973GlnPhe: 0.973 ± 0.028	2.054GlnGly: 2.054 ± 0.04	0.733GlnHis: 0.733 ± 0.021	1.966GlnIle: 1.966 ± 0.035	0.881GlnLys: 0.881 ± 0.027	3.314GlnLeu: 3.314 ± 0.052	0.793GlnMet: 0.793 ± 0.021	0.671GlnAsn: 0.671 ± 0.022	1.759GlnPro: 1.759 ± 0.043	1.398GlnGln: 1.398 ± 0.047	2.456GlnArg: 2.456 ± 0.045	1.846GlnSer: 1.846 ± 0.037	1.803GlnThr: 1.803 ± 0.043	2.554GlnVal: 2.554 ± 0.044	0.486GlnTrp: 0.486 ± 0.019	0.724GlnTyr: 0.724 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	7.751ArgAla: 7.751 ± 0.071	0.475ArgCys: 0.475 ± 0.02	4.184ArgAsp: 4.184 ± 0.063	3.943ArgGlu: 3.943 ± 0.062	2.073ArgPhe: 2.073 ± 0.041	4.916ArgGly: 4.916 ± 0.065	1.552ArgHis: 1.552 ± 0.032	3.453ArgIle: 3.453 ± 0.047	1.857ArgLys: 1.857 ± 0.033	6.761ArgLeu: 6.761 ± 0.089	1.669ArgMet: 1.669 ± 0.031	1.558ArgAsn: 1.558 ± 0.033	3.6ArgPro: 3.6 ± 0.064	2.149ArgGln: 2.149 ± 0.041	6.184ArgArg: 6.184 ± 0.078	4.098ArgSer: 4.098 ± 0.057	4.134ArgThr: 4.134 ± 0.056	5.091ArgVal: 5.091 ± 0.061	1.113ArgTrp: 1.113 ± 0.03	1.664ArgTyr: 1.664 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	7.371SerAla: 7.371 ± 0.087	0.402SerCys: 0.402 ± 0.017	3.672SerAsp: 3.672 ± 0.045	2.921SerGlu: 2.921 ± 0.05	1.88SerPhe: 1.88 ± 0.038	6.385SerGly: 6.385 ± 0.079	1.113SerHis: 1.113 ± 0.03	2.791SerIle: 2.791 ± 0.049	1.623SerLys: 1.623 ± 0.036	5.431SerLeu: 5.431 ± 0.067	1.49SerMet: 1.49 ± 0.037	1.374SerAsn: 1.374 ± 0.036	3.137SerPro: 3.137 ± 0.048	1.624SerGln: 1.624 ± 0.035	3.704SerArg: 3.704 ± 0.057	3.935SerSer: 3.935 ± 0.073	3.942SerThr: 3.942 ± 0.057	4.825SerVal: 4.825 ± 0.062	0.863SerTrp: 0.863 ± 0.027	1.468SerTyr: 1.468 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	7.515ThrAla: 7.515 ± 0.076	0.393ThrCys: 0.393 ± 0.02	3.893ThrAsp: 3.893 ± 0.066	3.074ThrGlu: 3.074 ± 0.05	1.843ThrPhe: 1.843 ± 0.037	5.783ThrGly: 5.783 ± 0.08	1.227ThrHis: 1.227 ± 0.027	2.975ThrIle: 2.975 ± 0.048	1.738ThrLys: 1.738 ± 0.04	5.469ThrLeu: 5.469 ± 0.067	1.298ThrMet: 1.298 ± 0.034	1.487ThrAsn: 1.487 ± 0.04	3.909ThrPro: 3.909 ± 0.058	1.603ThrGln: 1.603 ± 0.034	3.515ThrArg: 3.515 ± 0.048	3.823ThrSer: 3.823 ± 0.052	4.308ThrThr: 4.308 ± 0.081	5.39ThrVal: 5.39 ± 0.073	0.843ThrTrp: 0.843 ± 0.024	1.436ThrTyr: 1.436 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	10.638ValAla: 10.638 ± 0.109	0.68ValCys: 0.68 ± 0.02	5.435ValAsp: 5.435 ± 0.065	4.528ValGlu: 4.528 ± 0.058	2.47ValPhe: 2.47 ± 0.044	7.237ValGly: 7.237 ± 0.081	1.704ValHis: 1.704 ± 0.036	4.437ValIle: 4.437 ± 0.057	1.999ValLys: 1.999 ± 0.04	8.515ValLeu: 8.515 ± 0.092	1.64ValMet: 1.64 ± 0.036	1.898ValAsn: 1.898 ± 0.039	4.452ValPro: 4.452 ± 0.06	2.234ValGln: 2.234 ± 0.035	5.733ValArg: 5.733 ± 0.071	4.783ValSer: 4.783 ± 0.059	5.437ValThr: 5.437 ± 0.067	8.512ValVal: 8.512 ± 0.086	0.923ValTrp: 0.923 ± 0.027	1.547ValTyr: 1.547 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.404TrpAla: 1.404 ± 0.034	0.137TrpCys: 0.137 ± 0.011	0.765TrpAsp: 0.765 ± 0.024	0.558TrpGlu: 0.558 ± 0.02	0.447TrpPhe: 0.447 ± 0.019	0.977TrpGly: 0.977 ± 0.028	0.332TrpHis: 0.332 ± 0.015	0.694TrpIle: 0.694 ± 0.023	0.351TrpLys: 0.351 ± 0.016	1.61TrpLeu: 1.61 ± 0.036	0.346TrpMet: 0.346 ± 0.017	0.377TrpAsn: 0.377 ± 0.017	0.666TrpPro: 0.666 ± 0.024	0.521TrpGln: 0.521 ± 0.021	1.046TrpArg: 1.046 ± 0.026	0.897TrpSer: 0.897 ± 0.026	0.85TrpThr: 0.85 ± 0.022	1.024TrpVal: 1.024 ± 0.031	0.293TrpTrp: 0.293 ± 0.014	0.307TrpTyr: 0.307 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.816TyrAla: 2.816 ± 0.048	0.243TyrCys: 0.243 ± 0.013	1.766TyrAsp: 1.766 ± 0.034	1.09TyrGlu: 1.09 ± 0.03	0.797TyrPhe: 0.797 ± 0.025	2.235TyrGly: 2.235 ± 0.039	0.38TyrHis: 0.38 ± 0.018	0.792TyrIle: 0.792 ± 0.022	0.562TyrLys: 0.562 ± 0.023	2.324TyrLeu: 2.324 ± 0.045	0.321TyrMet: 0.321 ± 0.014	0.512TyrAsn: 0.512 ± 0.022	1.17TyrPro: 1.17 ± 0.029	0.692TyrGln: 0.692 ± 0.024	1.593TyrArg: 1.593 ± 0.028	1.179TyrSer: 1.179 ± 0.027	1.192TyrThr: 1.192 ± 0.033	1.875TyrVal: 1.875 ± 0.039	0.342TyrTrp: 0.342 ± 0.017	0.506TyrTyr: 0.506 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4340 proteins (1423240 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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