Talpa europaea papillomavirus 1

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Dyophipapillomavirus; Dyophipapillomavirus 1

Average proteome isoelectric point is 6.1

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|R9RYS7|R9RYS7_9PAPI Minor capsid protein L2 OS=Talpa europaea papillomavirus 1 OX=1338506 GN=L2 PE=3 SV=1
MM1 pKa = 7.65IGPEE5 pKa = 4.18PTLKK9 pKa = 10.63DD10 pKa = 3.2ITLDD14 pKa = 3.67TPDD17 pKa = 5.43SIDD20 pKa = 3.63LNCYY24 pKa = 6.56EE25 pKa = 4.06TFEE28 pKa = 4.3IEE30 pKa = 4.25EE31 pKa = 4.46EE32 pKa = 4.18EE33 pKa = 4.45VPPLGQPIKK42 pKa = 9.99VLCYY46 pKa = 10.24CGLCKK51 pKa = 10.06RR52 pKa = 11.84RR53 pKa = 11.84IKK55 pKa = 9.8VTVVSDD61 pKa = 3.65RR62 pKa = 11.84ASLISLEE69 pKa = 4.07SLLVDD74 pKa = 3.52SSLRR78 pKa = 11.84FVCCSCGRR86 pKa = 11.84RR87 pKa = 11.84YY88 pKa = 10.45GRR90 pKa = 4.21

Molecular weight:
10.1 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|R9RZM2|R9RZM2_9PAPI Regulatory protein E2 OS=Talpa europaea papillomavirus 1 OX=1338506 GN=E2 PE=3 SV=1
MM1 pKa = 7.14EE2 pKa = 4.63TLKK5 pKa = 10.56QRR7 pKa = 11.84LDD9 pKa = 3.44SLQNEE14 pKa = 4.42LLSLYY19 pKa = 10.33EE20 pKa = 4.53KK21 pKa = 10.56DD22 pKa = 3.79SNDD25 pKa = 2.84IRR27 pKa = 11.84DD28 pKa = 4.87QILHH32 pKa = 6.0WNLNRR37 pKa = 11.84RR38 pKa = 11.84EE39 pKa = 4.03QALLHH44 pKa = 5.75YY45 pKa = 10.38ARR47 pKa = 11.84QQGLNRR53 pKa = 11.84LGMQMVPALTVSQSRR68 pKa = 11.84AKK70 pKa = 10.58GAIEE74 pKa = 4.15MEE76 pKa = 4.27LMLTSLSTSRR86 pKa = 11.84FGNEE90 pKa = 2.99GWTLQEE96 pKa = 3.87TSRR99 pKa = 11.84EE100 pKa = 4.18LFNTAPKK107 pKa = 9.0HH108 pKa = 4.5TFKK111 pKa = 10.84KK112 pKa = 10.42GPRR115 pKa = 11.84HH116 pKa = 6.45LDD118 pKa = 3.19MIFDD122 pKa = 4.28GNSNNTVHH130 pKa = 6.26VPFWQYY136 pKa = 10.73IYY138 pKa = 10.89YY139 pKa = 9.86QDD141 pKa = 5.49EE142 pKa = 3.78RR143 pKa = 11.84DD144 pKa = 3.12EE145 pKa = 4.22WHH147 pKa = 7.02RR148 pKa = 11.84SNSDD152 pKa = 2.85VDD154 pKa = 4.07SVGIYY159 pKa = 10.52YY160 pKa = 8.27MQGTIKK166 pKa = 10.5VYY168 pKa = 7.4YY169 pKa = 10.05TKK171 pKa = 10.57FQSEE175 pKa = 3.77ASKK178 pKa = 11.14YY179 pKa = 10.38GFRR182 pKa = 11.84TWQVSHH188 pKa = 7.38DD189 pKa = 4.07NKK191 pKa = 10.06PLHH194 pKa = 6.68SSSSVGSRR202 pKa = 11.84GPSPHH207 pKa = 6.69SKK209 pKa = 10.68APSTPIRR216 pKa = 11.84RR217 pKa = 11.84GGGRR221 pKa = 11.84RR222 pKa = 11.84APRR225 pKa = 11.84RR226 pKa = 11.84RR227 pKa = 11.84SPSTFSRR234 pKa = 11.84SHH236 pKa = 6.69KK237 pKa = 9.39EE238 pKa = 3.6ASGSSGRR245 pKa = 11.84GEE247 pKa = 4.43TPPSARR253 pKa = 11.84DD254 pKa = 3.32VGRR257 pKa = 11.84STEE260 pKa = 4.04TPPRR264 pKa = 11.84GNQSRR269 pKa = 11.84LRR271 pKa = 11.84SLLHH275 pKa = 6.17EE276 pKa = 4.76ARR278 pKa = 11.84DD279 pKa = 3.88PPLLVLKK286 pKa = 10.9GPANTLKK293 pKa = 10.6CLRR296 pKa = 11.84YY297 pKa = 8.76RR298 pKa = 11.84LKK300 pKa = 11.11GRR302 pKa = 11.84FSHH305 pKa = 6.22TFCNVTSTWHH315 pKa = 4.85WTLPTGTEE323 pKa = 3.86KK324 pKa = 10.66CVRR327 pKa = 11.84SCGSRR332 pKa = 11.84MIVTFSSTEE341 pKa = 3.7QRR343 pKa = 11.84NLFCTKK349 pKa = 10.01VPLPSSVTAFTGSFNGEE366 pKa = 3.63

Molecular weight:
41.62 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2265

90

608

323.6

36.69

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.901 ± 0.575

1.987 ± 0.548

5.563 ± 0.576

7.285 ± 0.591

4.812 ± 0.443

5.916 ± 0.823

1.987 ± 0.332

4.989 ± 0.745

5.21 ± 0.825

9.36 ± 0.844

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.943 ± 0.458

4.459 ± 0.717

5.916 ± 1.017

4.194 ± 0.407

6.446 ± 0.885

8.079 ± 1.282

6.313 ± 0.569

6.269 ± 0.582

1.369 ± 0.304

3.002 ± 0.265

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski