Aquamavirus A (isolate Phoca hispida/Canada/HO.02.21/2002)

Taxonomy: Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Picornavirales; Picornaviridae; Aquamavirus; Aquamavirus A

Average proteome isoelectric point is 5.85

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

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* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A8D7N3|A8D7N3_AQUAV Capsid protein VP0 OS=Aquamavirus A (isolate Phoca hispida/Canada/HO.02.21/2002) OX=1554492 GN=SPV1gp1 PE=4 SV=1
MM1 pKa = 7.55EE2 pKa = 5.2SFVEE6 pKa = 4.58TVTKK10 pKa = 10.27SLPVVGPMVSAAEE23 pKa = 4.05TAVTNMLNPAGPSAPQAISAQEE45 pKa = 3.81QVQPQQIPEE54 pKa = 4.23PKK56 pKa = 8.86PVTVAMPNATYY67 pKa = 7.62TTSSDD72 pKa = 3.33VSFGPRR78 pKa = 11.84PPLGSDD84 pKa = 2.72IALSNAAAANTGALNQLKK102 pKa = 9.57FVEE105 pKa = 4.55VQQFVLRR112 pKa = 11.84NNTNPFTGIASFALPKK128 pKa = 10.15SYY130 pKa = 11.01YY131 pKa = 9.78SNKK134 pKa = 9.74EE135 pKa = 3.49FPQYY139 pKa = 10.9GNARR143 pKa = 11.84FFSMVRR149 pKa = 11.84SGFVAQLQVNVAPGSSGLYY168 pKa = 9.95LLAWCPPTQKK178 pKa = 10.69DD179 pKa = 4.55LSKK182 pKa = 10.92LDD184 pKa = 3.32YY185 pKa = 10.37RR186 pKa = 11.84AIGNFPSVLMDD197 pKa = 3.3ISRR200 pKa = 11.84MTTATLDD207 pKa = 3.04IPYY210 pKa = 9.88ISDD213 pKa = 3.35TNYY216 pKa = 10.39VKK218 pKa = 10.11IDD220 pKa = 3.98SDD222 pKa = 3.76DD223 pKa = 3.1QGYY226 pKa = 10.19ILVVPIAPYY235 pKa = 10.37NAGPQTDD242 pKa = 4.21SEE244 pKa = 4.69VLATMFVAARR254 pKa = 11.84EE255 pKa = 4.2GDD257 pKa = 4.08LQCPTPYY264 pKa = 10.12RR265 pKa = 11.84EE266 pKa = 4.29GFVKK270 pKa = 10.71PEE272 pKa = 4.18TYY274 pKa = 10.34PIMNIQNPPGAINLASFEE292 pKa = 4.37TALNAPSLALAGEE305 pKa = 4.16GHH307 pKa = 7.71LIDD310 pKa = 3.48THH312 pKa = 5.98TPGGYY317 pKa = 10.56APISDD322 pKa = 5.71LIDD325 pKa = 4.02LSHH328 pKa = 6.89IPSMVTNDD336 pKa = 3.18TTDD339 pKa = 3.0YY340 pKa = 11.13HH341 pKa = 7.47YY342 pKa = 11.06FDD344 pKa = 4.07WTDD347 pKa = 3.16TTNKK351 pKa = 10.64DD352 pKa = 3.46EE353 pKa = 5.63IIGKK357 pKa = 9.73FNFKK361 pKa = 10.56LNSVPNSAILANSYY375 pKa = 11.1SFFRR379 pKa = 11.84GPIIFHH385 pKa = 6.38VIAAASTMHH394 pKa = 7.16RR395 pKa = 11.84GRR397 pKa = 11.84LRR399 pKa = 11.84VCFRR403 pKa = 11.84PNSNQEE409 pKa = 3.55YY410 pKa = 10.07SAPQSMAVYY419 pKa = 10.15YY420 pKa = 10.5SLLDD424 pKa = 3.42ISQSNCCTLAVPFNSEE440 pKa = 2.89TWMRR444 pKa = 11.84STDD447 pKa = 3.6DD448 pKa = 3.19VLGRR452 pKa = 11.84LQIFVNNQLAANRR465 pKa = 11.84TAANHH470 pKa = 5.8VYY472 pKa = 10.5VYY474 pKa = 8.67VTASLGPDD482 pKa = 2.77AAFYY486 pKa = 10.54CPRR489 pKa = 11.84SGKK492 pKa = 9.62IEE494 pKa = 3.98FTDD497 pKa = 3.15QGNFEE502 pKa = 4.48SFLRR506 pKa = 11.84PPPPEE511 pKa = 4.0YY512 pKa = 9.78PVNAIPQKK520 pKa = 9.63TEE522 pKa = 3.72LFGEE526 pKa = 4.18SHH528 pKa = 6.58TLVKK532 pKa = 10.54HH533 pKa = 5.13LFGRR537 pKa = 11.84FTYY540 pKa = 10.42LGYY543 pKa = 8.83YY544 pKa = 9.15TPDD547 pKa = 2.9SGGWKK552 pKa = 9.62KK553 pKa = 10.56VALNIPKK560 pKa = 10.15RR561 pKa = 11.84GVVNLMRR568 pKa = 11.84AFCYY572 pKa = 9.68WSGEE576 pKa = 3.87AVLCITNNDD585 pKa = 3.91DD586 pKa = 3.72APVEE590 pKa = 4.12ITHH593 pKa = 6.46TFFDD597 pKa = 4.06QPDD600 pKa = 3.79EE601 pKa = 4.03LVDD604 pKa = 3.83MSSHH608 pKa = 6.37GSVLVPGKK616 pKa = 10.35SSVVTAVPFYY626 pKa = 10.88SLTPVRR632 pKa = 11.84SLSKK636 pKa = 9.94PDD638 pKa = 3.71PFGFLYY644 pKa = 10.07IAALGTSRR652 pKa = 11.84KK653 pKa = 9.45VVVHH657 pKa = 5.83LAFRR661 pKa = 11.84NLRR664 pKa = 11.84LYY666 pKa = 10.63LFSGFPILDD675 pKa = 3.52YY676 pKa = 11.49SKK678 pKa = 10.73LQSGCFCPLPNVYY691 pKa = 9.81VPPTHH696 pKa = 6.76NVLLDD701 pKa = 3.54GDD703 pKa = 4.38VEE705 pKa = 5.08SNPGPLYY712 pKa = 10.81VCSQPGKK719 pKa = 9.91CDD721 pKa = 3.41PFPPVLGKK729 pKa = 10.67YY730 pKa = 9.38YY731 pKa = 10.92AFASNYY737 pKa = 8.76VQDD740 pKa = 4.45HH741 pKa = 5.73VCSCFLPKK749 pKa = 10.46VIVEE753 pKa = 3.94ARR755 pKa = 11.84VLIKK759 pKa = 7.88PTPICFMCYY768 pKa = 9.44FSHH771 pKa = 7.89KK772 pKa = 10.18IRR774 pKa = 11.84DD775 pKa = 3.69FTEE778 pKa = 3.41ARR780 pKa = 11.84IICHH784 pKa = 6.14GSCEE788 pKa = 4.04RR789 pKa = 11.84HH790 pKa = 6.34SIDD793 pKa = 4.81YY794 pKa = 8.66EE795 pKa = 4.39PPCKK799 pKa = 9.72RR800 pKa = 11.84RR801 pKa = 11.84LVLDD805 pKa = 3.62VEE807 pKa = 4.73EE808 pKa = 4.17QGFMDD813 pKa = 3.83VVCRR817 pKa = 11.84MFSATYY823 pKa = 9.15HH824 pKa = 6.52DD825 pKa = 4.67KK826 pKa = 11.08VLRR829 pKa = 11.84DD830 pKa = 3.46HH831 pKa = 7.02KK832 pKa = 11.14NYY834 pKa = 10.2IIRR837 pKa = 11.84SCLNMLALSMSNDD850 pKa = 3.09KK851 pKa = 10.82CVSAIVAAAITYY863 pKa = 7.5DD864 pKa = 3.5TVTVVPPAEE873 pKa = 4.17LKK875 pKa = 10.94YY876 pKa = 10.99LITLLVAQTYY886 pKa = 10.7DD887 pKa = 3.28VFVNALSLVFGRR899 pKa = 11.84LPRR902 pKa = 11.84NVYY905 pKa = 10.07DD906 pKa = 3.26VARR909 pKa = 11.84RR910 pKa = 11.84VFSSRR915 pKa = 11.84PTQQGFASFTSALRR929 pKa = 11.84ACEE932 pKa = 3.73WWIKK936 pKa = 9.69TIAKK940 pKa = 8.92FVSWVKK946 pKa = 7.01TTCFSNPLVGEE957 pKa = 4.23ARR959 pKa = 11.84DD960 pKa = 3.66QLSEE964 pKa = 4.1LLAAAEE970 pKa = 3.92QLVLDD975 pKa = 4.44VVNLAIPRR983 pKa = 11.84EE984 pKa = 4.22VIEE987 pKa = 4.21ARR989 pKa = 11.84RR990 pKa = 11.84SNILDD995 pKa = 3.41KK996 pKa = 11.24LSYY999 pKa = 10.53AKK1001 pKa = 10.22KK1002 pKa = 10.06LSVNIPEE1009 pKa = 5.24LDD1011 pKa = 3.42ALVNKK1016 pKa = 10.46ASLALRR1022 pKa = 11.84KK1023 pKa = 10.0VPATYY1028 pKa = 8.43VTPSHH1033 pKa = 6.65PRR1035 pKa = 11.84VEE1037 pKa = 4.23PLGVWLRR1044 pKa = 11.84GAPGSGKK1051 pKa = 10.41SILMCKK1057 pKa = 10.09LARR1060 pKa = 11.84DD1061 pKa = 3.47VSLIKK1066 pKa = 10.61NSSVFYY1072 pKa = 10.68HH1073 pKa = 5.53PTGSNFFSGYY1083 pKa = 8.77HH1084 pKa = 4.92GQYY1087 pKa = 8.99VHH1089 pKa = 7.3CIDD1092 pKa = 6.05DD1093 pKa = 4.28LGQNKK1098 pKa = 9.79DD1099 pKa = 3.63EE1100 pKa = 4.99KK1101 pKa = 10.68DD1102 pKa = 3.0ISLICQCISSSHH1114 pKa = 5.24FTAPMANIEE1123 pKa = 4.47DD1124 pKa = 4.08KK1125 pKa = 11.39AMQYY1129 pKa = 10.94SSNLVIATTNMTSFRR1144 pKa = 11.84TYY1146 pKa = 10.86TLTTPAALEE1155 pKa = 3.82RR1156 pKa = 11.84RR1157 pKa = 11.84FPLVCDD1163 pKa = 3.97IVPKK1167 pKa = 10.0YY1168 pKa = 10.61SKK1170 pKa = 10.92PNGTLNLNFDD1180 pKa = 4.3PHH1182 pKa = 6.94DD1183 pKa = 3.83CWKK1186 pKa = 8.89ITCNGQEE1193 pKa = 4.15MCYY1196 pKa = 9.59MDD1198 pKa = 5.47LFNLVLEE1205 pKa = 4.54RR1206 pKa = 11.84LTEE1209 pKa = 4.03RR1210 pKa = 11.84EE1211 pKa = 4.0KK1212 pKa = 11.23LHH1214 pKa = 9.08ADD1216 pKa = 3.08MCRR1219 pKa = 11.84QNNEE1223 pKa = 4.18LDD1225 pKa = 3.86DD1226 pKa = 5.68LEE1228 pKa = 6.17IDD1230 pKa = 3.49DD1231 pKa = 6.23DD1232 pKa = 3.94IRR1234 pKa = 11.84AKK1236 pKa = 10.43ISLPFHH1242 pKa = 6.34TPFDD1246 pKa = 5.66DD1247 pKa = 3.63IVQMQCPYY1255 pKa = 9.37TVEE1258 pKa = 3.84RR1259 pKa = 11.84KK1260 pKa = 9.69KK1261 pKa = 11.06FYY1263 pKa = 10.8DD1264 pKa = 3.73RR1265 pKa = 11.84YY1266 pKa = 10.18LSSIKK1271 pKa = 9.92SDD1273 pKa = 3.59KK1274 pKa = 10.64LSHH1277 pKa = 6.17TATLVIGMLCGASLFTLATHH1297 pKa = 7.07AFSFVSNCFSHH1308 pKa = 7.64GEE1310 pKa = 4.11DD1311 pKa = 4.06PPGPGPDD1318 pKa = 3.22CVRR1321 pKa = 11.84LPEE1324 pKa = 4.18SAYY1327 pKa = 9.97EE1328 pKa = 4.34GCSTRR1333 pKa = 11.84KK1334 pKa = 7.61TARR1337 pKa = 11.84QLARR1341 pKa = 11.84SVVGEE1346 pKa = 3.88GAYY1349 pKa = 10.51DD1350 pKa = 3.68GNVKK1354 pKa = 9.08RR1355 pKa = 11.84TTARR1359 pKa = 11.84EE1360 pKa = 4.09LARR1363 pKa = 11.84KK1364 pKa = 9.22AIPSEE1369 pKa = 3.96QGPSDD1374 pKa = 3.46VSEE1377 pKa = 4.42FVHH1380 pKa = 6.72LLKK1383 pKa = 10.78FCAYY1387 pKa = 10.15VEE1389 pKa = 4.63TPSGPVFGVILGGRR1403 pKa = 11.84KK1404 pKa = 8.62MYY1406 pKa = 10.76FNTHH1410 pKa = 4.98YY1411 pKa = 11.12ASVILDD1417 pKa = 3.5KK1418 pKa = 11.11DD1419 pKa = 3.94VTVCTPNKK1427 pKa = 10.3KK1428 pKa = 10.29YY1429 pKa = 8.5FTRR1432 pKa = 11.84LTKK1435 pKa = 10.51VSSNYY1440 pKa = 9.37DD1441 pKa = 3.39TMIVQLDD1448 pKa = 3.83IPEE1451 pKa = 4.76LLPSISKK1458 pKa = 10.05YY1459 pKa = 10.41VSSSVPADD1467 pKa = 3.26ALLLYY1472 pKa = 7.97FTGKK1476 pKa = 10.3GFYY1479 pKa = 9.31SQSVSQVSYY1488 pKa = 10.44LPCLEE1493 pKa = 4.16VRR1495 pKa = 11.84EE1496 pKa = 4.5GMHH1499 pKa = 6.02GASYY1503 pKa = 10.68AYY1505 pKa = 7.13TTRR1508 pKa = 11.84TQKK1511 pKa = 10.82GMCGGLLVGKK1521 pKa = 10.14IDD1523 pKa = 4.02GAFKK1527 pKa = 11.04ALGFHH1532 pKa = 6.98AAGSLEE1538 pKa = 4.01RR1539 pKa = 11.84GFANAFNSVPPLSTVPDD1556 pKa = 4.43FPEE1559 pKa = 4.62SINLSGLFSNDD1570 pKa = 2.63VEE1572 pKa = 4.51GVVVGQFEE1580 pKa = 4.7GEE1582 pKa = 4.01MLHH1585 pKa = 7.43RR1586 pKa = 11.84SIRR1589 pKa = 11.84TKK1591 pKa = 10.45FRR1593 pKa = 11.84PTDD1596 pKa = 3.73LQNKK1600 pKa = 8.58IVPEE1604 pKa = 4.23LEE1606 pKa = 3.98PAVLSASDD1614 pKa = 3.95PRR1616 pKa = 11.84LKK1618 pKa = 10.9VQIDD1622 pKa = 3.76GDD1624 pKa = 4.38LPDD1627 pKa = 4.75HH1628 pKa = 6.72LCKK1631 pKa = 10.1KK1632 pKa = 9.11WKK1634 pKa = 10.64VNTKK1638 pKa = 8.65VSRR1641 pKa = 11.84PDD1643 pKa = 3.26VLEE1646 pKa = 4.05LVVNEE1651 pKa = 4.7YY1652 pKa = 10.28ISSLDD1657 pKa = 3.61CEE1659 pKa = 4.25QFEE1662 pKa = 4.24PVTLNEE1668 pKa = 5.17AINSSEE1674 pKa = 4.39SPLNFNGTAGAKK1686 pKa = 8.99YY1687 pKa = 9.52PGMNRR1692 pKa = 11.84RR1693 pKa = 11.84QLLLPLNPQVRR1704 pKa = 11.84DD1705 pKa = 3.8DD1706 pKa = 3.99VVKK1709 pKa = 10.75LAGDD1713 pKa = 3.75VGNGTATVVFEE1724 pKa = 4.4TFMKK1728 pKa = 10.82DD1729 pKa = 2.96EE1730 pKa = 4.68LRR1732 pKa = 11.84PKK1734 pKa = 10.48EE1735 pKa = 4.25KK1736 pKa = 10.04IEE1738 pKa = 4.11SGKK1741 pKa = 8.04TRR1743 pKa = 11.84IVEE1746 pKa = 4.25SCPLDD1751 pKa = 3.54YY1752 pKa = 11.28LLLYY1756 pKa = 10.21RR1757 pKa = 11.84MVMLKK1762 pKa = 10.91SMIWWYY1768 pKa = 11.22NSDD1771 pKa = 4.05CIKK1774 pKa = 10.3TGVAPGMNVYY1784 pKa = 10.14TDD1786 pKa = 3.98FVPMVKK1792 pKa = 9.74QFKK1795 pKa = 9.67KK1796 pKa = 10.38IKK1798 pKa = 8.92YY1799 pKa = 8.79CLDD1802 pKa = 3.69FSAYY1806 pKa = 10.46DD1807 pKa = 3.44STLSDD1812 pKa = 4.3EE1813 pKa = 4.22ILAAGVEE1820 pKa = 4.46VLACTSAVPSYY1831 pKa = 10.52VRR1833 pKa = 11.84KK1834 pKa = 9.21LHH1836 pKa = 6.66APIICSHH1843 pKa = 6.39HH1844 pKa = 4.35WHH1846 pKa = 6.49NNVVDD1851 pKa = 4.53LVLGGMPSGAPCTSVLNSIVNVLMARR1877 pKa = 11.84YY1878 pKa = 9.01ICALMDD1884 pKa = 3.14IDD1886 pKa = 4.36YY1887 pKa = 9.62PVMVAYY1893 pKa = 10.32GDD1895 pKa = 4.29DD1896 pKa = 3.6NVVSFDD1902 pKa = 3.66EE1903 pKa = 5.05EE1904 pKa = 3.88IDD1906 pKa = 3.4IEE1908 pKa = 5.05RR1909 pKa = 11.84MVSLYY1914 pKa = 9.08KK1915 pKa = 10.47TEE1917 pKa = 4.56FGVTATNHH1925 pKa = 6.82DD1926 pKa = 4.18KK1927 pKa = 11.1TPVPRR1932 pKa = 11.84PMANPVFLKK1941 pKa = 10.43RR1942 pKa = 11.84RR1943 pKa = 11.84LRR1945 pKa = 11.84FNPDD1949 pKa = 2.89LNIQFPVLPLGEE1961 pKa = 4.79MIDD1964 pKa = 3.71RR1965 pKa = 11.84MCWTRR1970 pKa = 11.84GPEE1973 pKa = 4.0HH1974 pKa = 7.06LSDD1977 pKa = 3.4QTFSFAIEE1985 pKa = 3.53LAGYY1989 pKa = 8.18GKK1991 pKa = 9.78QVYY1994 pKa = 7.21THH1996 pKa = 6.45IRR1998 pKa = 11.84DD1999 pKa = 3.27AFFPYY2004 pKa = 9.87MILPPYY2010 pKa = 10.73SLMEE2014 pKa = 3.76NTVRR2018 pKa = 11.84SVCGLNPVQSFLSKK2032 pKa = 11.32YY2033 pKa = 10.72NFGPDD2038 pKa = 3.16DD2039 pKa = 3.97RR2040 pKa = 11.84KK2041 pKa = 10.99KK2042 pKa = 10.81KK2043 pKa = 10.92GIGCWPWW2050 pKa = 3.11

Molecular weight:
227.65 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A8D7N3|A8D7N3_AQUAV Capsid protein VP0 OS=Aquamavirus A (isolate Phoca hispida/Canada/HO.02.21/2002) OX=1554492 GN=SPV1gp1 PE=4 SV=1
MM1 pKa = 7.55EE2 pKa = 5.2SFVEE6 pKa = 4.58TVTKK10 pKa = 10.27SLPVVGPMVSAAEE23 pKa = 4.05TAVTNMLNPAGPSAPQAISAQEE45 pKa = 3.81QVQPQQIPEE54 pKa = 4.23PKK56 pKa = 8.86PVTVAMPNATYY67 pKa = 7.62TTSSDD72 pKa = 3.33VSFGPRR78 pKa = 11.84PPLGSDD84 pKa = 2.72IALSNAAAANTGALNQLKK102 pKa = 9.57FVEE105 pKa = 4.55VQQFVLRR112 pKa = 11.84NNTNPFTGIASFALPKK128 pKa = 10.15SYY130 pKa = 11.01YY131 pKa = 9.78SNKK134 pKa = 9.74EE135 pKa = 3.49FPQYY139 pKa = 10.9GNARR143 pKa = 11.84FFSMVRR149 pKa = 11.84SGFVAQLQVNVAPGSSGLYY168 pKa = 9.95LLAWCPPTQKK178 pKa = 10.69DD179 pKa = 4.55LSKK182 pKa = 10.92LDD184 pKa = 3.32YY185 pKa = 10.37RR186 pKa = 11.84AIGNFPSVLMDD197 pKa = 3.3ISRR200 pKa = 11.84MTTATLDD207 pKa = 3.04IPYY210 pKa = 9.88ISDD213 pKa = 3.35TNYY216 pKa = 10.39VKK218 pKa = 10.11IDD220 pKa = 3.98SDD222 pKa = 3.76DD223 pKa = 3.1QGYY226 pKa = 10.19ILVVPIAPYY235 pKa = 10.37NAGPQTDD242 pKa = 4.21SEE244 pKa = 4.69VLATMFVAARR254 pKa = 11.84EE255 pKa = 4.2GDD257 pKa = 4.08LQCPTPYY264 pKa = 10.12RR265 pKa = 11.84EE266 pKa = 4.29GFVKK270 pKa = 10.71PEE272 pKa = 4.18TYY274 pKa = 10.34PIMNIQNPPGAINLASFEE292 pKa = 4.37TALNAPSLALAGEE305 pKa = 4.16GHH307 pKa = 7.71LIDD310 pKa = 3.48THH312 pKa = 5.98TPGGYY317 pKa = 10.56APISDD322 pKa = 5.71LIDD325 pKa = 4.02LSHH328 pKa = 6.89IPSMVTNDD336 pKa = 3.18TTDD339 pKa = 3.0YY340 pKa = 11.13HH341 pKa = 7.47YY342 pKa = 11.06FDD344 pKa = 4.07WTDD347 pKa = 3.16TTNKK351 pKa = 10.64DD352 pKa = 3.46EE353 pKa = 5.63IIGKK357 pKa = 9.73FNFKK361 pKa = 10.56LNSVPNSAILANSYY375 pKa = 11.1SFFRR379 pKa = 11.84GPIIFHH385 pKa = 6.38VIAAASTMHH394 pKa = 7.16RR395 pKa = 11.84GRR397 pKa = 11.84LRR399 pKa = 11.84VCFRR403 pKa = 11.84PNSNQEE409 pKa = 3.55YY410 pKa = 10.07SAPQSMAVYY419 pKa = 10.15YY420 pKa = 10.5SLLDD424 pKa = 3.42ISQSNCCTLAVPFNSEE440 pKa = 2.89TWMRR444 pKa = 11.84STDD447 pKa = 3.6DD448 pKa = 3.19VLGRR452 pKa = 11.84LQIFVNNQLAANRR465 pKa = 11.84TAANHH470 pKa = 5.8VYY472 pKa = 10.5VYY474 pKa = 8.67VTASLGPDD482 pKa = 2.77AAFYY486 pKa = 10.54CPRR489 pKa = 11.84SGKK492 pKa = 9.62IEE494 pKa = 3.98FTDD497 pKa = 3.15QGNFEE502 pKa = 4.48SFLRR506 pKa = 11.84PPPPEE511 pKa = 4.0YY512 pKa = 9.78PVNAIPQKK520 pKa = 9.63TEE522 pKa = 3.72LFGEE526 pKa = 4.18SHH528 pKa = 6.58TLVKK532 pKa = 10.54HH533 pKa = 5.13LFGRR537 pKa = 11.84FTYY540 pKa = 10.42LGYY543 pKa = 8.83YY544 pKa = 9.15TPDD547 pKa = 2.9SGGWKK552 pKa = 9.62KK553 pKa = 10.56VALNIPKK560 pKa = 10.15RR561 pKa = 11.84GVVNLMRR568 pKa = 11.84AFCYY572 pKa = 9.68WSGEE576 pKa = 3.87AVLCITNNDD585 pKa = 3.91DD586 pKa = 3.72APVEE590 pKa = 4.12ITHH593 pKa = 6.46TFFDD597 pKa = 4.06QPDD600 pKa = 3.79EE601 pKa = 4.03LVDD604 pKa = 3.83MSSHH608 pKa = 6.37GSVLVPGKK616 pKa = 10.35SSVVTAVPFYY626 pKa = 10.88SLTPVRR632 pKa = 11.84SLSKK636 pKa = 9.94PDD638 pKa = 3.71PFGFLYY644 pKa = 10.07IAALGTSRR652 pKa = 11.84KK653 pKa = 9.45VVVHH657 pKa = 5.83LAFRR661 pKa = 11.84NLRR664 pKa = 11.84LYY666 pKa = 10.63LFSGFPILDD675 pKa = 3.52YY676 pKa = 11.49SKK678 pKa = 10.73LQSGCFCPLPNVYY691 pKa = 9.81VPPTHH696 pKa = 6.76NVLLDD701 pKa = 3.54GDD703 pKa = 4.38VEE705 pKa = 5.08SNPGPLYY712 pKa = 10.81VCSQPGKK719 pKa = 9.91CDD721 pKa = 3.41PFPPVLGKK729 pKa = 10.67YY730 pKa = 9.38YY731 pKa = 10.92AFASNYY737 pKa = 8.76VQDD740 pKa = 4.45HH741 pKa = 5.73VCSCFLPKK749 pKa = 10.46VIVEE753 pKa = 3.94ARR755 pKa = 11.84VLIKK759 pKa = 7.88PTPICFMCYY768 pKa = 9.44FSHH771 pKa = 7.89KK772 pKa = 10.18IRR774 pKa = 11.84DD775 pKa = 3.69FTEE778 pKa = 3.41ARR780 pKa = 11.84IICHH784 pKa = 6.14GSCEE788 pKa = 4.04RR789 pKa = 11.84HH790 pKa = 6.34SIDD793 pKa = 4.81YY794 pKa = 8.66EE795 pKa = 4.39PPCKK799 pKa = 9.72RR800 pKa = 11.84RR801 pKa = 11.84LVLDD805 pKa = 3.62VEE807 pKa = 4.73EE808 pKa = 4.17QGFMDD813 pKa = 3.83VVCRR817 pKa = 11.84MFSATYY823 pKa = 9.15HH824 pKa = 6.52DD825 pKa = 4.67KK826 pKa = 11.08VLRR829 pKa = 11.84DD830 pKa = 3.46HH831 pKa = 7.02KK832 pKa = 11.14NYY834 pKa = 10.2IIRR837 pKa = 11.84SCLNMLALSMSNDD850 pKa = 3.09KK851 pKa = 10.82CVSAIVAAAITYY863 pKa = 7.5DD864 pKa = 3.5TVTVVPPAEE873 pKa = 4.17LKK875 pKa = 10.94YY876 pKa = 10.99LITLLVAQTYY886 pKa = 10.7DD887 pKa = 3.28VFVNALSLVFGRR899 pKa = 11.84LPRR902 pKa = 11.84NVYY905 pKa = 10.07DD906 pKa = 3.26VARR909 pKa = 11.84RR910 pKa = 11.84VFSSRR915 pKa = 11.84PTQQGFASFTSALRR929 pKa = 11.84ACEE932 pKa = 3.73WWIKK936 pKa = 9.69TIAKK940 pKa = 8.92FVSWVKK946 pKa = 7.01TTCFSNPLVGEE957 pKa = 4.23ARR959 pKa = 11.84DD960 pKa = 3.66QLSEE964 pKa = 4.1LLAAAEE970 pKa = 3.92QLVLDD975 pKa = 4.44VVNLAIPRR983 pKa = 11.84EE984 pKa = 4.22VIEE987 pKa = 4.21ARR989 pKa = 11.84RR990 pKa = 11.84SNILDD995 pKa = 3.41KK996 pKa = 11.24LSYY999 pKa = 10.53AKK1001 pKa = 10.22KK1002 pKa = 10.06LSVNIPEE1009 pKa = 5.24LDD1011 pKa = 3.42ALVNKK1016 pKa = 10.46ASLALRR1022 pKa = 11.84KK1023 pKa = 10.0VPATYY1028 pKa = 8.43VTPSHH1033 pKa = 6.65PRR1035 pKa = 11.84VEE1037 pKa = 4.23PLGVWLRR1044 pKa = 11.84GAPGSGKK1051 pKa = 10.41SILMCKK1057 pKa = 10.09LARR1060 pKa = 11.84DD1061 pKa = 3.47VSLIKK1066 pKa = 10.61NSSVFYY1072 pKa = 10.68HH1073 pKa = 5.53PTGSNFFSGYY1083 pKa = 8.77HH1084 pKa = 4.92GQYY1087 pKa = 8.99VHH1089 pKa = 7.3CIDD1092 pKa = 6.05DD1093 pKa = 4.28LGQNKK1098 pKa = 9.79DD1099 pKa = 3.63EE1100 pKa = 4.99KK1101 pKa = 10.68DD1102 pKa = 3.0ISLICQCISSSHH1114 pKa = 5.24FTAPMANIEE1123 pKa = 4.47DD1124 pKa = 4.08KK1125 pKa = 11.39AMQYY1129 pKa = 10.94SSNLVIATTNMTSFRR1144 pKa = 11.84TYY1146 pKa = 10.86TLTTPAALEE1155 pKa = 3.82RR1156 pKa = 11.84RR1157 pKa = 11.84FPLVCDD1163 pKa = 3.97IVPKK1167 pKa = 10.0YY1168 pKa = 10.61SKK1170 pKa = 10.92PNGTLNLNFDD1180 pKa = 4.3PHH1182 pKa = 6.94DD1183 pKa = 3.83CWKK1186 pKa = 8.89ITCNGQEE1193 pKa = 4.15MCYY1196 pKa = 9.59MDD1198 pKa = 5.47LFNLVLEE1205 pKa = 4.54RR1206 pKa = 11.84LTEE1209 pKa = 4.03RR1210 pKa = 11.84EE1211 pKa = 4.0KK1212 pKa = 11.23LHH1214 pKa = 9.08ADD1216 pKa = 3.08MCRR1219 pKa = 11.84QNNEE1223 pKa = 4.18LDD1225 pKa = 3.86DD1226 pKa = 5.68LEE1228 pKa = 6.17IDD1230 pKa = 3.49DD1231 pKa = 6.23DD1232 pKa = 3.94IRR1234 pKa = 11.84AKK1236 pKa = 10.43ISLPFHH1242 pKa = 6.34TPFDD1246 pKa = 5.66DD1247 pKa = 3.63IVQMQCPYY1255 pKa = 9.37TVEE1258 pKa = 3.84RR1259 pKa = 11.84KK1260 pKa = 9.69KK1261 pKa = 11.06FYY1263 pKa = 10.8DD1264 pKa = 3.73RR1265 pKa = 11.84YY1266 pKa = 10.18LSSIKK1271 pKa = 9.92SDD1273 pKa = 3.59KK1274 pKa = 10.64LSHH1277 pKa = 6.17TATLVIGMLCGASLFTLATHH1297 pKa = 7.07AFSFVSNCFSHH1308 pKa = 7.64GEE1310 pKa = 4.11DD1311 pKa = 4.06PPGPGPDD1318 pKa = 3.22CVRR1321 pKa = 11.84LPEE1324 pKa = 4.18SAYY1327 pKa = 9.97EE1328 pKa = 4.34GCSTRR1333 pKa = 11.84KK1334 pKa = 7.61TARR1337 pKa = 11.84QLARR1341 pKa = 11.84SVVGEE1346 pKa = 3.88GAYY1349 pKa = 10.51DD1350 pKa = 3.68GNVKK1354 pKa = 9.08RR1355 pKa = 11.84TTARR1359 pKa = 11.84EE1360 pKa = 4.09LARR1363 pKa = 11.84KK1364 pKa = 9.22AIPSEE1369 pKa = 3.96QGPSDD1374 pKa = 3.46VSEE1377 pKa = 4.42FVHH1380 pKa = 6.72LLKK1383 pKa = 10.78FCAYY1387 pKa = 10.15VEE1389 pKa = 4.63TPSGPVFGVILGGRR1403 pKa = 11.84KK1404 pKa = 8.62MYY1406 pKa = 10.76FNTHH1410 pKa = 4.98YY1411 pKa = 11.12ASVILDD1417 pKa = 3.5KK1418 pKa = 11.11DD1419 pKa = 3.94VTVCTPNKK1427 pKa = 10.3KK1428 pKa = 10.29YY1429 pKa = 8.5FTRR1432 pKa = 11.84LTKK1435 pKa = 10.51VSSNYY1440 pKa = 9.37DD1441 pKa = 3.39TMIVQLDD1448 pKa = 3.83IPEE1451 pKa = 4.76LLPSISKK1458 pKa = 10.05YY1459 pKa = 10.41VSSSVPADD1467 pKa = 3.26ALLLYY1472 pKa = 7.97FTGKK1476 pKa = 10.3GFYY1479 pKa = 9.31SQSVSQVSYY1488 pKa = 10.44LPCLEE1493 pKa = 4.16VRR1495 pKa = 11.84EE1496 pKa = 4.5GMHH1499 pKa = 6.02GASYY1503 pKa = 10.68AYY1505 pKa = 7.13TTRR1508 pKa = 11.84TQKK1511 pKa = 10.82GMCGGLLVGKK1521 pKa = 10.14IDD1523 pKa = 4.02GAFKK1527 pKa = 11.04ALGFHH1532 pKa = 6.98AAGSLEE1538 pKa = 4.01RR1539 pKa = 11.84GFANAFNSVPPLSTVPDD1556 pKa = 4.43FPEE1559 pKa = 4.62SINLSGLFSNDD1570 pKa = 2.63VEE1572 pKa = 4.51GVVVGQFEE1580 pKa = 4.7GEE1582 pKa = 4.01MLHH1585 pKa = 7.43RR1586 pKa = 11.84SIRR1589 pKa = 11.84TKK1591 pKa = 10.45FRR1593 pKa = 11.84PTDD1596 pKa = 3.73LQNKK1600 pKa = 8.58IVPEE1604 pKa = 4.23LEE1606 pKa = 3.98PAVLSASDD1614 pKa = 3.95PRR1616 pKa = 11.84LKK1618 pKa = 10.9VQIDD1622 pKa = 3.76GDD1624 pKa = 4.38LPDD1627 pKa = 4.75HH1628 pKa = 6.72LCKK1631 pKa = 10.1KK1632 pKa = 9.11WKK1634 pKa = 10.64VNTKK1638 pKa = 8.65VSRR1641 pKa = 11.84PDD1643 pKa = 3.26VLEE1646 pKa = 4.05LVVNEE1651 pKa = 4.7YY1652 pKa = 10.28ISSLDD1657 pKa = 3.61CEE1659 pKa = 4.25QFEE1662 pKa = 4.24PVTLNEE1668 pKa = 5.17AINSSEE1674 pKa = 4.39SPLNFNGTAGAKK1686 pKa = 8.99YY1687 pKa = 9.52PGMNRR1692 pKa = 11.84RR1693 pKa = 11.84QLLLPLNPQVRR1704 pKa = 11.84DD1705 pKa = 3.8DD1706 pKa = 3.99VVKK1709 pKa = 10.75LAGDD1713 pKa = 3.75VGNGTATVVFEE1724 pKa = 4.4TFMKK1728 pKa = 10.82DD1729 pKa = 2.96EE1730 pKa = 4.68LRR1732 pKa = 11.84PKK1734 pKa = 10.48EE1735 pKa = 4.25KK1736 pKa = 10.04IEE1738 pKa = 4.11SGKK1741 pKa = 8.04TRR1743 pKa = 11.84IVEE1746 pKa = 4.25SCPLDD1751 pKa = 3.54YY1752 pKa = 11.28LLLYY1756 pKa = 10.21RR1757 pKa = 11.84MVMLKK1762 pKa = 10.91SMIWWYY1768 pKa = 11.22NSDD1771 pKa = 4.05CIKK1774 pKa = 10.3TGVAPGMNVYY1784 pKa = 10.14TDD1786 pKa = 3.98FVPMVKK1792 pKa = 9.74QFKK1795 pKa = 9.67KK1796 pKa = 10.38IKK1798 pKa = 8.92YY1799 pKa = 8.79CLDD1802 pKa = 3.69FSAYY1806 pKa = 10.46DD1807 pKa = 3.44STLSDD1812 pKa = 4.3EE1813 pKa = 4.22ILAAGVEE1820 pKa = 4.46VLACTSAVPSYY1831 pKa = 10.52VRR1833 pKa = 11.84KK1834 pKa = 9.21LHH1836 pKa = 6.66APIICSHH1843 pKa = 6.39HH1844 pKa = 4.35WHH1846 pKa = 6.49NNVVDD1851 pKa = 4.53LVLGGMPSGAPCTSVLNSIVNVLMARR1877 pKa = 11.84YY1878 pKa = 9.01ICALMDD1884 pKa = 3.14IDD1886 pKa = 4.36YY1887 pKa = 9.62PVMVAYY1893 pKa = 10.32GDD1895 pKa = 4.29DD1896 pKa = 3.6NVVSFDD1902 pKa = 3.66EE1903 pKa = 5.05EE1904 pKa = 3.88IDD1906 pKa = 3.4IEE1908 pKa = 5.05RR1909 pKa = 11.84MVSLYY1914 pKa = 9.08KK1915 pKa = 10.47TEE1917 pKa = 4.56FGVTATNHH1925 pKa = 6.82DD1926 pKa = 4.18KK1927 pKa = 11.1TPVPRR1932 pKa = 11.84PMANPVFLKK1941 pKa = 10.43RR1942 pKa = 11.84RR1943 pKa = 11.84LRR1945 pKa = 11.84FNPDD1949 pKa = 2.89LNIQFPVLPLGEE1961 pKa = 4.79MIDD1964 pKa = 3.71RR1965 pKa = 11.84MCWTRR1970 pKa = 11.84GPEE1973 pKa = 4.0HH1974 pKa = 7.06LSDD1977 pKa = 3.4QTFSFAIEE1985 pKa = 3.53LAGYY1989 pKa = 8.18GKK1991 pKa = 9.78QVYY1994 pKa = 7.21THH1996 pKa = 6.45IRR1998 pKa = 11.84DD1999 pKa = 3.27AFFPYY2004 pKa = 9.87MILPPYY2010 pKa = 10.73SLMEE2014 pKa = 3.76NTVRR2018 pKa = 11.84SVCGLNPVQSFLSKK2032 pKa = 11.32YY2033 pKa = 10.72NFGPDD2038 pKa = 3.16DD2039 pKa = 3.97RR2040 pKa = 11.84KK2041 pKa = 10.99KK2042 pKa = 10.81KK2043 pKa = 10.92GIGCWPWW2050 pKa = 3.11

Molecular weight:
227.65 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

1

0

1

2050

2050

2050

2050.0

227.65

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.024 ± 0.0

2.634 ± 0.0

5.561 ± 0.0

4.341 ± 0.0

5.024 ± 0.0

5.512 ± 0.0

2.098 ± 0.0

4.829 ± 0.0

4.732 ± 0.0

9.073 ± 0.0

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.488 ± 0.0

4.878 ± 0.0

7.122 ± 0.0

2.878 ± 0.0

4.488 ± 0.0

8.0 ± 0.0

5.756 ± 0.0

8.488 ± 0.0

0.829 ± 0.0

4.244 ± 0.0

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski