Human herpesvirus 8 (HHV-8) (Kaposi s sarcoma-associated herpesvirus)
Average proteome isoelectric point is 6.88
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 87 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|D0UZU4|D0UZU4_HHV8 ORF75 OS=Human herpesvirus 8 OX=37296 GN=ORF75 PE=2 SV=1
MM1 pKa = 7.75 APPGMRR7 pKa = 11.84 LRR9 pKa = 11.84 SGRR12 pKa = 11.84 STGAPLTRR20 pKa = 11.84 GSCRR24 pKa = 11.84 KK25 pKa = 9.62 RR26 pKa = 11.84 NRR28 pKa = 11.84 SPEE31 pKa = 3.97 RR32 pKa = 11.84 CDD34 pKa = 5.09 LGDD37 pKa = 4.86 DD38 pKa = 3.78 LHH40 pKa = 6.35 LQPRR44 pKa = 11.84 RR45 pKa = 11.84 KK46 pKa = 9.5 HH47 pKa = 5.62 VADD50 pKa = 3.58 SVDD53 pKa = 3.17 GRR55 pKa = 11.84 EE56 pKa = 4.62 CGPHH60 pKa = 5.99 TLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLPPVTTSSSPIPPSHH118 pKa = 6.71 PVSPGTTDD126 pKa = 2.91 THH128 pKa = 6.78 SPSPALPPTQSPEE141 pKa = 3.81 SSQRR145 pKa = 11.84 PPLSSPTGRR154 pKa = 11.84 PDD156 pKa = 2.63 SSTPMRR162 pKa = 11.84 PPPSQQTTPPHH173 pKa = 6.63 SPTTPPPEE181 pKa = 4.72 PPSKK185 pKa = 10.64 SSPDD189 pKa = 3.28 SLAPSTLRR197 pKa = 11.84 SLRR200 pKa = 11.84 KK201 pKa = 9.2 RR202 pKa = 11.84 RR203 pKa = 11.84 LSSPQGPSTLNPICQSPPVSPPRR226 pKa = 11.84 CDD228 pKa = 3.09 FANRR232 pKa = 11.84 SVYY235 pKa = 10.06 PPWATEE241 pKa = 3.69 SPIYY245 pKa = 10.41 VGSSSDD251 pKa = 3.01 GDD253 pKa = 3.85 TPPRR257 pKa = 11.84 QPPTSPISIGSSSPSEE273 pKa = 4.18 GSWGDD278 pKa = 3.52 DD279 pKa = 2.79 TAMLVLLAEE288 pKa = 4.45 IAEE291 pKa = 4.14 EE292 pKa = 3.7 ASKK295 pKa = 11.3 NEE297 pKa = 4.25 KK298 pKa = 9.88 EE299 pKa = 4.32 CSEE302 pKa = 4.02 NNQAGEE308 pKa = 4.28 DD309 pKa = 3.65 NGDD312 pKa = 3.55 NEE314 pKa = 4.33 ISKK317 pKa = 10.3 EE318 pKa = 4.18 SQVDD322 pKa = 3.67 KK323 pKa = 11.19 DD324 pKa = 4.68 DD325 pKa = 4.5 NDD327 pKa = 3.72 NKK329 pKa = 10.87 DD330 pKa = 3.69 DD331 pKa = 4.22 EE332 pKa = 4.92 EE333 pKa = 4.21 EE334 pKa = 4.3 QEE336 pKa = 3.97 TDD338 pKa = 4.05 EE339 pKa = 4.96 EE340 pKa = 4.57 DD341 pKa = 3.94 EE342 pKa = 4.7 EE343 pKa = 6.24 DD344 pKa = 5.14 DD345 pKa = 5.21 EE346 pKa = 6.18 EE347 pKa = 6.72 DD348 pKa = 5.0 DD349 pKa = 5.25 EE350 pKa = 6.16 EE351 pKa = 6.7 DD352 pKa = 5.0 DD353 pKa = 5.25 EE354 pKa = 6.16 EE355 pKa = 6.7 DD356 pKa = 5.0 DD357 pKa = 5.25 EE358 pKa = 6.16 EE359 pKa = 6.7 DD360 pKa = 5.0 DD361 pKa = 5.25 EE362 pKa = 6.16 EE363 pKa = 6.7 DD364 pKa = 5.0 DD365 pKa = 5.25 EE366 pKa = 6.16 EE367 pKa = 6.7 DD368 pKa = 5.0 DD369 pKa = 4.88 EE370 pKa = 6.06 EE371 pKa = 6.43 DD372 pKa = 5.02 DD373 pKa = 4.1 EE374 pKa = 5.75 EE375 pKa = 4.55 EE376 pKa = 5.15 DD377 pKa = 3.76 EE378 pKa = 5.3 EE379 pKa = 4.38 EE380 pKa = 5.36 DD381 pKa = 3.77 EE382 pKa = 5.16 EE383 pKa = 4.41 EE384 pKa = 4.92 DD385 pKa = 4.21 EE386 pKa = 4.38 EE387 pKa = 5.04 EE388 pKa = 3.96 EE389 pKa = 4.88 DD390 pKa = 3.95 EE391 pKa = 4.88 EE392 pKa = 4.59 EE393 pKa = 5.03 EE394 pKa = 4.72 EE395 pKa = 5.79 DD396 pKa = 5.51 EE397 pKa = 5.53 EE398 pKa = 6.97 DD399 pKa = 6.31 DD400 pKa = 5.53 DD401 pKa = 7.12 DD402 pKa = 5.49 EE403 pKa = 6.88 DD404 pKa = 5.88 NEE406 pKa = 4.97 DD407 pKa = 3.85 EE408 pKa = 4.7 EE409 pKa = 6.42 DD410 pKa = 5.51 DD411 pKa = 3.92 EE412 pKa = 5.88 EE413 pKa = 4.28 EE414 pKa = 4.41 DD415 pKa = 4.01 KK416 pKa = 11.62 KK417 pKa = 11.23 EE418 pKa = 4.03 DD419 pKa = 3.96 EE420 pKa = 4.45 EE421 pKa = 6.55 DD422 pKa = 3.72 GGDD425 pKa = 3.74 GNKK428 pKa = 8.77 TLSIQSSQQQQEE440 pKa = 4.2 PQQQEE445 pKa = 4.09 PQQQEE450 pKa = 4.09 PQQQEE455 pKa = 4.09 PQQQEE460 pKa = 4.09 PQQQEE465 pKa = 4.09 PQQQEE470 pKa = 4.09 PQQQEE475 pKa = 3.9 PQQRR479 pKa = 11.84 EE480 pKa = 3.91 PQQRR484 pKa = 11.84 EE485 pKa = 3.78 PQQRR489 pKa = 11.84 EE490 pKa = 3.78 PQQRR494 pKa = 11.84 EE495 pKa = 3.78 PQQRR499 pKa = 11.84 EE500 pKa = 3.78 PQQRR504 pKa = 11.84 EE505 pKa = 3.94 PQQQEE510 pKa = 3.96 PQQQEE515 pKa = 4.09 PQQQEE520 pKa = 4.09 PQQQEE525 pKa = 4.09 PQQQEE530 pKa = 4.09 PQQQEE535 pKa = 4.09 PQQQEE540 pKa = 4.09 PQQQEE545 pKa = 4.09 PQQQEE550 pKa = 4.09 PQQQEE555 pKa = 4.09 PQQQEE560 pKa = 4.09 PQQQEE565 pKa = 4.09 PQQQEE570 pKa = 4.09 PQQQEE575 pKa = 4.09 PQQQEE580 pKa = 3.99 PQQQDD585 pKa = 3.2 EE586 pKa = 4.35 QQQDD590 pKa = 3.38 EE591 pKa = 4.34 QQQDD595 pKa = 3.38 EE596 pKa = 4.34 QQQDD600 pKa = 3.38 EE601 pKa = 4.34 QQQDD605 pKa = 3.38 EE606 pKa = 4.37 QQQDD610 pKa = 3.42 EE611 pKa = 4.55 QEE613 pKa = 4.31 QQDD616 pKa = 3.86 EE617 pKa = 4.34 QQQDD621 pKa = 3.34 EE622 pKa = 4.35 QQQQDD627 pKa = 3.49 EE628 pKa = 4.51 QEE630 pKa = 4.15 QQEE633 pKa = 4.3 EE634 pKa = 4.39 QEE636 pKa = 4.16 QQEE639 pKa = 4.29 EE640 pKa = 4.38 QEE642 pKa = 4.16 QQEE645 pKa = 4.29 EE646 pKa = 4.38 QEE648 pKa = 4.16 QQEE651 pKa = 4.35 EE652 pKa = 4.41 QEE654 pKa = 4.38 QEE656 pKa = 4.17 LEE658 pKa = 4.15 EE659 pKa = 4.07 QEE661 pKa = 4.42 QEE663 pKa = 4.69 LEE665 pKa = 4.15 EE666 pKa = 4.07 QEE668 pKa = 4.42 QEE670 pKa = 4.69 LEE672 pKa = 4.15 EE673 pKa = 4.07 QEE675 pKa = 4.42 QEE677 pKa = 4.69 LEE679 pKa = 4.15 EE680 pKa = 4.07 QEE682 pKa = 4.42 QEE684 pKa = 4.69 LEE686 pKa = 4.15 EE687 pKa = 4.07 QEE689 pKa = 4.42 QEE691 pKa = 4.69 LEE693 pKa = 4.15 EE694 pKa = 4.07 QEE696 pKa = 4.42 QEE698 pKa = 4.69 LEE700 pKa = 4.15 EE701 pKa = 4.07 QEE703 pKa = 4.42 QEE705 pKa = 4.69 LEE707 pKa = 4.15 EE708 pKa = 4.07 QEE710 pKa = 4.42 QEE712 pKa = 4.69 LEE714 pKa = 4.15 EE715 pKa = 4.07 QEE717 pKa = 4.42 QEE719 pKa = 4.69 LEE721 pKa = 4.15 EE722 pKa = 4.07 QEE724 pKa = 4.42 QEE726 pKa = 4.69 LEE728 pKa = 4.15 EE729 pKa = 4.07 QEE731 pKa = 4.42 QEE733 pKa = 4.69 LEE735 pKa = 4.15 EE736 pKa = 4.07 QEE738 pKa = 4.42 QEE740 pKa = 4.69 LEE742 pKa = 4.15 EE743 pKa = 4.07 QEE745 pKa = 4.42 QEE747 pKa = 4.69 LEE749 pKa = 4.15 EE750 pKa = 4.07 QEE752 pKa = 4.42 QEE754 pKa = 4.69 LEE756 pKa = 4.15 EE757 pKa = 4.07 QEE759 pKa = 4.42 QEE761 pKa = 4.69 LEE763 pKa = 4.15 EE764 pKa = 4.07 QEE766 pKa = 4.42 QEE768 pKa = 4.69 LEE770 pKa = 4.15 EE771 pKa = 4.07 QEE773 pKa = 4.42 QEE775 pKa = 4.69 LEE777 pKa = 4.15 EE778 pKa = 4.07 QEE780 pKa = 4.42 QEE782 pKa = 4.69 LEE784 pKa = 4.15 EE785 pKa = 4.07 QEE787 pKa = 4.42 QEE789 pKa = 4.69 LEE791 pKa = 4.15 EE792 pKa = 4.07 QEE794 pKa = 4.42 QEE796 pKa = 4.69 LEE798 pKa = 4.15 EE799 pKa = 4.07 QEE801 pKa = 4.42 QEE803 pKa = 4.69 LEE805 pKa = 4.15 EE806 pKa = 4.07 QEE808 pKa = 4.42 QEE810 pKa = 4.69 LEE812 pKa = 4.17 EE813 pKa = 4.1 QEE815 pKa = 4.24 QEE817 pKa = 4.08 QEE819 pKa = 4.07 LEE821 pKa = 4.06 EE822 pKa = 4.42 VEE824 pKa = 4.38 EE825 pKa = 4.22 QEE827 pKa = 4.93 QEE829 pKa = 4.04 QEE831 pKa = 4.12 EE832 pKa = 4.52 QEE834 pKa = 4.18 LEE836 pKa = 4.06 EE837 pKa = 4.61 VEE839 pKa = 4.38 EE840 pKa = 4.22 QEE842 pKa = 4.93 QEE844 pKa = 3.97 QEE846 pKa = 4.09 EE847 pKa = 4.39 QEE849 pKa = 4.2 EE850 pKa = 4.48 QEE852 pKa = 4.15 LEE854 pKa = 4.05 EE855 pKa = 4.34 VEE857 pKa = 4.21 EE858 pKa = 4.21 QEE860 pKa = 4.18 EE861 pKa = 4.43 QEE863 pKa = 4.13 LEE865 pKa = 4.05 EE866 pKa = 4.34 VEE868 pKa = 4.21 EE869 pKa = 4.21 QEE871 pKa = 4.18 EE872 pKa = 4.43 QEE874 pKa = 4.13 LEE876 pKa = 4.06 EE877 pKa = 4.74 VEE879 pKa = 4.41 EE880 pKa = 4.22 QEE882 pKa = 4.27 QQGVEE887 pKa = 4.0 QQEE890 pKa = 4.31 QEE892 pKa = 4.47 TVEE895 pKa = 4.17 EE896 pKa = 4.66 PIILHH901 pKa = 6.37 GSSSEE906 pKa = 4.27 DD907 pKa = 3.39 EE908 pKa = 4.5 MEE910 pKa = 3.4 VDD912 pKa = 3.84 YY913 pKa = 10.89 PVVSTHH919 pKa = 5.49 EE920 pKa = 4.56 QIASSPPGDD929 pKa = 3.92 NTPDD933 pKa = 5.1 DD934 pKa = 4.93 DD935 pKa = 4.49 PQPGPSRR942 pKa = 11.84 EE943 pKa = 3.78 YY944 pKa = 10.3 RR945 pKa = 11.84 YY946 pKa = 10.66 VLRR949 pKa = 11.84 TSPPHH954 pKa = 5.87 RR955 pKa = 11.84 PGVRR959 pKa = 11.84 MRR961 pKa = 11.84 RR962 pKa = 11.84 VPVTHH967 pKa = 7.12 PKK969 pKa = 10.05 KK970 pKa = 9.84 PHH972 pKa = 6.45 PRR974 pKa = 11.84 YY975 pKa = 8.97 QQPPVPYY982 pKa = 9.64 RR983 pKa = 11.84 QIDD986 pKa = 3.68 DD987 pKa = 4.36 CPAKK991 pKa = 10.46 ARR993 pKa = 11.84 PQHH996 pKa = 4.69 IFYY999 pKa = 10.7 RR1000 pKa = 11.84 RR1001 pKa = 11.84 FLGKK1005 pKa = 10.01 DD1006 pKa = 2.94 GRR1008 pKa = 11.84 RR1009 pKa = 11.84 DD1010 pKa = 3.68 PKK1012 pKa = 10.69 CQWKK1016 pKa = 9.05 FAVIFWGNDD1025 pKa = 2.98 PYY1027 pKa = 11.57 GLKK1030 pKa = 10.41 KK1031 pKa = 10.79 LSQAFQFGGVKK1042 pKa = 10.3 AGPVSCLPHH1051 pKa = 6.94 PGPDD1055 pKa = 3.33 QSPITYY1061 pKa = 9.65 CVYY1064 pKa = 10.48 VYY1066 pKa = 10.17 CQNKK1070 pKa = 8.21 DD1071 pKa = 3.17 TSKK1074 pKa = 10.09 KK1075 pKa = 9.13 VQMARR1080 pKa = 11.84 LAWEE1084 pKa = 4.34 ASHH1087 pKa = 7.2 PLAGNLQSSIVKK1099 pKa = 9.82 FKK1101 pKa = 11.13 KK1102 pKa = 9.77 PLPLTQPGEE1111 pKa = 4.15 NQGPGDD1117 pKa = 4.34 SPQEE1121 pKa = 3.99 MTT1123 pKa = 4.75
Molecular weight: 130.48 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 4.225
IPC2_protein 3.783
IPC_protein 3.757
Toseland 3.592
ProMoST 3.859
Dawson 3.694
Bjellqvist 3.846
Wikipedia 3.528
Rodwell 3.592
Grimsley 3.503
Solomon 3.694
Lehninger 3.643
Nozaki 3.795
DTASelect 3.897
Thurlkill 3.592
EMBOSS 3.554
Sillero 3.859
Patrickios 3.401
IPC_peptide 3.706
IPC2_peptide 3.859
IPC2.peptide.svr19 3.798
Protein with the highest isoelectric point:
>tr|Q76RG8|Q76RG8_HHV8 Uracil-DNA glycosylase OS=Human herpesvirus 8 OX=37296 GN=ORF46 PE=3 SV=1
MM1 pKa = 7.87 GIFALFAVLWTTLLVTSHH19 pKa = 6.98 AYY21 pKa = 9.38 VALPCCAIQASAASTLPLFFAVHH44 pKa = 6.91 SIHH47 pKa = 6.77 FADD50 pKa = 4.69 PNHH53 pKa = 6.68 CNGVCIAKK61 pKa = 9.92 LRR63 pKa = 11.84 SKK65 pKa = 9.72 TGDD68 pKa = 3.01 ITVEE72 pKa = 3.89 TCVNGFNLRR81 pKa = 11.84 SFLVAVVRR89 pKa = 11.84 RR90 pKa = 11.84 LGSWASQEE98 pKa = 3.94 NLRR101 pKa = 11.84 LLWYY105 pKa = 9.38 LQRR108 pKa = 11.84 SLTAYY113 pKa = 8.81 TVGFNATTADD123 pKa = 3.69 SSIHH127 pKa = 5.66 NVNIIIISVGKK138 pKa = 10.46 AMNRR142 pKa = 11.84 TGSVSGSQTRR152 pKa = 11.84 AKK154 pKa = 10.17 SSSRR158 pKa = 11.84 RR159 pKa = 11.84 AHH161 pKa = 6.74 AGQKK165 pKa = 10.08 GKK167 pKa = 10.65
Molecular weight: 18.0 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 9.313
IPC2_protein 9.443
IPC_protein 9.721
Toseland 10.262
ProMoST 10.014
Dawson 10.423
Bjellqvist 10.131
Wikipedia 10.584
Rodwell 10.774
Grimsley 10.482
Solomon 10.482
Lehninger 10.452
Nozaki 10.35
DTASelect 10.101
Thurlkill 10.306
EMBOSS 10.672
Sillero 10.365
Patrickios 10.526
IPC_peptide 10.482
IPC2_peptide 9.399
IPC2.peptide.svr19 8.304
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
86
1
87
38936
60
2635
447.5
49.67
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
7.589 ± 0.311
2.537 ± 0.171
4.664 ± 0.143
5.607 ± 0.528
4.148 ± 0.162
6.161 ± 0.235
2.761 ± 0.098
4.531 ± 0.152
3.745 ± 0.164
10.379 ± 0.27
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.06 ± 0.116
3.218 ± 0.164
6.968 ± 0.336
4.389 ± 0.436
5.858 ± 0.16
7.664 ± 0.218
6.58 ± 0.208
6.963 ± 0.24
1.22 ± 0.085
2.959 ± 0.126
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here