Amino acid dipepetide frequency for Arenimonas terrae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.011AlaAla: 20.011 ± 0.24	1.276AlaCys: 1.276 ± 0.035	7.504AlaAsp: 7.504 ± 0.092	8.142AlaGlu: 8.142 ± 0.112	4.154AlaPhe: 4.154 ± 0.07	12.209AlaGly: 12.209 ± 0.129	2.411AlaHis: 2.411 ± 0.047	5.071AlaIle: 5.071 ± 0.073	3.48AlaLys: 3.48 ± 0.077	15.949AlaLeu: 15.949 ± 0.174	3.362AlaMet: 3.362 ± 0.064	2.734AlaAsn: 2.734 ± 0.062	7.212AlaPro: 7.212 ± 0.129	4.759AlaGln: 4.759 ± 0.075	10.374AlaArg: 10.374 ± 0.132	6.06AlaSer: 6.06 ± 0.077	6.069AlaThr: 6.069 ± 0.091	9.177AlaVal: 9.177 ± 0.11	2.352AlaTrp: 2.352 ± 0.059	2.494AlaTyr: 2.494 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	1.048CysAla: 1.048 ± 0.034	0.112CysCys: 0.112 ± 0.012	0.444CysAsp: 0.444 ± 0.025	0.451CysGlu: 0.451 ± 0.022	0.283CysPhe: 0.283 ± 0.016	0.912CysGly: 0.912 ± 0.037	0.232CysHis: 0.232 ± 0.017	0.278CysIle: 0.278 ± 0.018	0.163CysLys: 0.163 ± 0.013	0.874CysLeu: 0.874 ± 0.031	0.101CysMet: 0.101 ± 0.011	0.185CysAsn: 0.185 ± 0.014	0.463CysPro: 0.463 ± 0.024	0.24CysGln: 0.24 ± 0.016	0.693CysArg: 0.693 ± 0.026	0.41CysSer: 0.41 ± 0.023	0.42CysThr: 0.42 ± 0.022	0.61CysVal: 0.61 ± 0.025	0.109CysTrp: 0.109 ± 0.011	0.184CysTyr: 0.184 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.857AspAla: 7.857 ± 0.096	0.45AspCys: 0.45 ± 0.023	3.17AspAsp: 3.17 ± 0.058	3.413AspGlu: 3.413 ± 0.058	2.192AspPhe: 2.192 ± 0.049	5.889AspGly: 5.889 ± 0.108	1.136AspHis: 1.136 ± 0.035	2.174AspIle: 2.174 ± 0.055	1.402AspLys: 1.402 ± 0.041	5.96AspLeu: 5.96 ± 0.083	1.007AspMet: 1.007 ± 0.036	1.112AspAsn: 1.112 ± 0.04	3.772AspPro: 3.772 ± 0.07	1.808AspGln: 1.808 ± 0.04	4.38AspArg: 4.38 ± 0.067	2.402AspSer: 2.402 ± 0.048	2.629AspThr: 2.629 ± 0.046	3.946AspVal: 3.946 ± 0.068	1.106AspTrp: 1.106 ± 0.035	1.72AspTyr: 1.72 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	8.048GluAla: 8.048 ± 0.121	0.348GluCys: 0.348 ± 0.019	2.665GluAsp: 2.665 ± 0.054	2.531GluGlu: 2.531 ± 0.07	1.921GluPhe: 1.921 ± 0.046	4.341GluGly: 4.341 ± 0.072	1.393GluHis: 1.393 ± 0.034	2.546GluIle: 2.546 ± 0.057	1.713GluLys: 1.713 ± 0.048	6.512GluLeu: 6.512 ± 0.097	1.137GluMet: 1.137 ± 0.035	1.288GluAsn: 1.288 ± 0.035	2.91GluPro: 2.91 ± 0.057	2.457GluGln: 2.457 ± 0.052	5.401GluArg: 5.401 ± 0.079	2.679GluSer: 2.679 ± 0.053	2.857GluThr: 2.857 ± 0.06	4.007GluVal: 4.007 ± 0.066	0.706GluTrp: 0.706 ± 0.027	0.995GluTyr: 0.995 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	4.396PheAla: 4.396 ± 0.067	0.338PheCys: 0.338 ± 0.02	2.537PheAsp: 2.537 ± 0.058	2.226PheGlu: 2.226 ± 0.049	1.207PhePhe: 1.207 ± 0.043	3.48PheGly: 3.48 ± 0.069	0.76PheHis: 0.76 ± 0.027	1.173PheIle: 1.173 ± 0.04	0.828PheLys: 0.828 ± 0.033	3.316PheLeu: 3.316 ± 0.061	0.6PheMet: 0.6 ± 0.026	0.99PheAsn: 0.99 ± 0.034	1.533PhePro: 1.533 ± 0.038	0.978PheGln: 0.978 ± 0.031	2.398PheArg: 2.398 ± 0.053	2.03PheSer: 2.03 ± 0.049	1.711PheThr: 1.711 ± 0.044	2.616PheVal: 2.616 ± 0.049	0.511PheTrp: 0.511 ± 0.027	0.823PheTyr: 0.823 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	9.612GlyAla: 9.612 ± 0.113	0.797GlyCys: 0.797 ± 0.031	5.087GlyAsp: 5.087 ± 0.084	5.397GlyGlu: 5.397 ± 0.084	3.553GlyPhe: 3.553 ± 0.068	7.459GlyGly: 7.459 ± 0.118	2.132GlyHis: 2.132 ± 0.047	3.681GlyIle: 3.681 ± 0.066	3.005GlyLys: 3.005 ± 0.071	10.061GlyLeu: 10.061 ± 0.128	2.096GlyMet: 2.096 ± 0.046	2.276GlyAsn: 2.276 ± 0.081	3.584GlyPro: 3.584 ± 0.065	3.334GlyGln: 3.334 ± 0.057	7.081GlyArg: 7.081 ± 0.1	4.502GlySer: 4.502 ± 0.074	4.229GlyThr: 4.229 ± 0.096	6.269GlyVal: 6.269 ± 0.094	1.57GlyTrp: 1.57 ± 0.045	2.377GlyTyr: 2.377 ± 0.063	0.0GlyXaa: 0.0 ± 0.0
His	2.813HisAla: 2.813 ± 0.062	0.257HisCys: 0.257 ± 0.017	1.263HisAsp: 1.263 ± 0.041	1.19HisGlu: 1.19 ± 0.033	0.862HisPhe: 0.862 ± 0.031	2.188HisGly: 2.188 ± 0.046	0.577HisHis: 0.577 ± 0.027	0.656HisIle: 0.656 ± 0.024	0.42HisLys: 0.42 ± 0.02	2.23HisLeu: 2.23 ± 0.054	0.357HisMet: 0.357 ± 0.019	0.419HisAsn: 0.419 ± 0.023	1.486HisPro: 1.486 ± 0.036	0.663HisGln: 0.663 ± 0.028	1.791HisArg: 1.791 ± 0.048	0.955HisSer: 0.955 ± 0.032	0.864HisThr: 0.864 ± 0.032	1.428HisVal: 1.428 ± 0.04	0.409HisTrp: 0.409 ± 0.022	0.658HisTyr: 0.658 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.841IleAla: 5.841 ± 0.08	0.317IleCys: 0.317 ± 0.017	2.632IleAsp: 2.632 ± 0.052	2.947IleGlu: 2.947 ± 0.06	1.003IlePhe: 1.003 ± 0.034	3.918IleGly: 3.918 ± 0.086	0.789IleHis: 0.789 ± 0.029	1.143IleIle: 1.143 ± 0.04	1.01IleLys: 1.01 ± 0.04	3.039IleLeu: 3.039 ± 0.064	0.477IleMet: 0.477 ± 0.023	1.116IleAsn: 1.116 ± 0.039	1.93IlePro: 1.93 ± 0.049	1.074IleGln: 1.074 ± 0.034	2.564IleArg: 2.564 ± 0.051	1.939IleSer: 1.939 ± 0.045	2.115IleThr: 2.115 ± 0.052	3.005IleVal: 3.005 ± 0.056	0.389IleTrp: 0.389 ± 0.022	0.803IleTyr: 0.803 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	3.41LysAla: 3.41 ± 0.082	0.134LysCys: 0.134 ± 0.015	1.433LysAsp: 1.433 ± 0.046	1.207LysGlu: 1.207 ± 0.044	0.793LysPhe: 0.793 ± 0.033	1.952LysGly: 1.952 ± 0.053	0.566LysHis: 0.566 ± 0.028	1.087LysIle: 1.087 ± 0.034	1.032LysLys: 1.032 ± 0.055	3.086LysLeu: 3.086 ± 0.063	0.524LysMet: 0.524 ± 0.025	0.674LysAsn: 0.674 ± 0.027	1.88LysPro: 1.88 ± 0.05	0.953LysGln: 0.953 ± 0.034	2.013LysArg: 2.013 ± 0.047	1.205LysSer: 1.205 ± 0.036	1.342LysThr: 1.342 ± 0.043	2.11LysVal: 2.11 ± 0.054	0.257LysTrp: 0.257 ± 0.017	0.61LysTyr: 0.61 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	17.302LeuAla: 17.302 ± 0.212	0.919LeuCys: 0.919 ± 0.033	6.901LeuAsp: 6.901 ± 0.104	5.764LeuGlu: 5.764 ± 0.087	3.529LeuPhe: 3.529 ± 0.069	9.35LeuGly: 9.35 ± 0.123	2.284LeuHis: 2.284 ± 0.06	3.62LeuIle: 3.62 ± 0.063	2.978LeuLys: 2.978 ± 0.061	12.005LeuLeu: 12.005 ± 0.188	2.263LeuMet: 2.263 ± 0.05	2.151LeuAsn: 2.151 ± 0.051	6.922LeuPro: 6.922 ± 0.104	3.722LeuGln: 3.722 ± 0.068	9.389LeuArg: 9.389 ± 0.122	6.192LeuSer: 6.192 ± 0.079	4.681LeuThr: 4.681 ± 0.072	8.811LeuVal: 8.811 ± 0.114	1.435LeuTrp: 1.435 ± 0.048	2.107LeuTyr: 2.107 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.746MetAla: 2.746 ± 0.055	0.121MetCys: 0.121 ± 0.01	1.159MetAsp: 1.159 ± 0.031	0.857MetGlu: 0.857 ± 0.033	0.619MetPhe: 0.619 ± 0.027	1.517MetGly: 1.517 ± 0.044	0.42MetHis: 0.42 ± 0.021	0.814MetIle: 0.814 ± 0.028	0.782MetLys: 0.782 ± 0.028	2.261MetLeu: 2.261 ± 0.043	0.413MetMet: 0.413 ± 0.021	0.665MetAsn: 0.665 ± 0.026	1.371MetPro: 1.371 ± 0.045	0.747MetGln: 0.747 ± 0.026	1.643MetArg: 1.643 ± 0.046	1.475MetSer: 1.475 ± 0.039	1.257MetThr: 1.257 ± 0.033	1.378MetVal: 1.378 ± 0.04	0.194MetTrp: 0.194 ± 0.013	0.323MetTyr: 0.323 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.898AsnAla: 2.898 ± 0.053	0.196AsnCys: 0.196 ± 0.016	1.24AsnAsp: 1.24 ± 0.049	1.096AsnGlu: 1.096 ± 0.036	0.872AsnPhe: 0.872 ± 0.032	2.07AsnGly: 2.07 ± 0.06	0.49AsnHis: 0.49 ± 0.02	0.939AsnIle: 0.939 ± 0.032	0.539AsnLys: 0.539 ± 0.025	2.481AsnLeu: 2.481 ± 0.063	0.355AsnMet: 0.355 ± 0.02	0.58AsnAsn: 0.58 ± 0.029	1.643AsnPro: 1.643 ± 0.045	0.727AsnGln: 0.727 ± 0.035	1.686AsnArg: 1.686 ± 0.045	1.007AsnSer: 1.007 ± 0.039	1.176AsnThr: 1.176 ± 0.038	1.648AsnVal: 1.648 ± 0.047	0.313AsnTrp: 0.313 ± 0.017	0.637AsnTyr: 0.637 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	8.501ProAla: 8.501 ± 0.13	0.318ProCys: 0.318 ± 0.018	3.758ProAsp: 3.758 ± 0.061	3.838ProGlu: 3.838 ± 0.071	1.665ProPhe: 1.665 ± 0.036	5.649ProGly: 5.649 ± 0.091	1.055ProHis: 1.055 ± 0.031	1.787ProIle: 1.787 ± 0.044	1.353ProLys: 1.353 ± 0.043	5.45ProLeu: 5.45 ± 0.087	1.388ProMet: 1.388 ± 0.036	1.103ProAsn: 1.103 ± 0.032	3.176ProPro: 3.176 ± 0.078	1.78ProGln: 1.78 ± 0.042	3.81ProArg: 3.81 ± 0.073	2.582ProSer: 2.582 ± 0.053	2.395ProThr: 2.395 ± 0.056	4.723ProVal: 4.723 ± 0.082	0.818ProTrp: 0.818 ± 0.029	1.115ProTyr: 1.115 ± 0.042	0.0ProXaa: 0.0 ± 0.0
Gln	5.311GlnAla: 5.311 ± 0.08	0.219GlnCys: 0.219 ± 0.016	1.545GlnAsp: 1.545 ± 0.045	1.412GlnGlu: 1.412 ± 0.042	1.07GlnPhe: 1.07 ± 0.029	2.793GlnGly: 2.793 ± 0.054	0.755GlnHis: 0.755 ± 0.028	1.355GlnIle: 1.355 ± 0.04	0.856GlnLys: 0.856 ± 0.033	3.881GlnLeu: 3.881 ± 0.076	0.761GlnMet: 0.761 ± 0.026	0.635GlnAsn: 0.635 ± 0.03	2.032GlnPro: 2.032 ± 0.054	1.407GlnGln: 1.407 ± 0.045	3.438GlnArg: 3.438 ± 0.059	1.562GlnSer: 1.562 ± 0.038	1.379GlnThr: 1.379 ± 0.039	2.891GlnVal: 2.891 ± 0.06	0.537GlnTrp: 0.537 ± 0.024	0.658GlnTyr: 0.658 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	9.244ArgAla: 9.244 ± 0.114	0.673ArgCys: 0.673 ± 0.028	4.628ArgAsp: 4.628 ± 0.067	5.09ArgGlu: 5.09 ± 0.072	3.088ArgPhe: 3.088 ± 0.058	6.036ArgGly: 6.036 ± 0.076	2.06ArgHis: 2.06 ± 0.05	3.762ArgIle: 3.762 ± 0.067	1.957ArgLys: 1.957 ± 0.059	9.773ArgLeu: 9.773 ± 0.136	1.811ArgMet: 1.811 ± 0.044	1.742ArgAsn: 1.742 ± 0.046	4.029ArgPro: 4.029 ± 0.064	3.058ArgGln: 3.058 ± 0.06	7.022ArgArg: 7.022 ± 0.106	3.593ArgSer: 3.593 ± 0.063	3.26ArgThr: 3.26 ± 0.056	5.499ArgVal: 5.499 ± 0.083	1.492ArgTrp: 1.492 ± 0.042	2.141ArgTyr: 2.141 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	6.085SerAla: 6.085 ± 0.083	0.362SerCys: 0.362 ± 0.018	2.562SerAsp: 2.562 ± 0.049	2.588SerGlu: 2.588 ± 0.049	1.908SerPhe: 1.908 ± 0.043	5.017SerGly: 5.017 ± 0.083	1.082SerHis: 1.082 ± 0.031	1.865SerIle: 1.865 ± 0.049	1.198SerLys: 1.198 ± 0.036	5.767SerLeu: 5.767 ± 0.08	0.929SerMet: 0.929 ± 0.033	1.149SerAsn: 1.149 ± 0.034	2.892SerPro: 2.892 ± 0.054	1.553SerGln: 1.553 ± 0.039	3.816SerArg: 3.816 ± 0.064	2.335SerSer: 2.335 ± 0.056	2.436SerThr: 2.436 ± 0.054	3.593SerVal: 3.593 ± 0.078	0.746SerTrp: 0.746 ± 0.027	1.215SerTyr: 1.215 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	5.864ThrAla: 5.864 ± 0.089	0.391ThrCys: 0.391 ± 0.019	2.498ThrAsp: 2.498 ± 0.062	2.198ThrGlu: 2.198 ± 0.046	1.47ThrPhe: 1.47 ± 0.045	4.696ThrGly: 4.696 ± 0.086	0.984ThrHis: 0.984 ± 0.031	1.742ThrIle: 1.742 ± 0.051	0.847ThrLys: 0.847 ± 0.033	5.895ThrLeu: 5.895 ± 0.089	0.883ThrMet: 0.883 ± 0.029	0.928ThrAsn: 0.928 ± 0.04	3.398ThrPro: 3.398 ± 0.07	1.357ThrGln: 1.357 ± 0.037	3.363ThrArg: 3.363 ± 0.062	2.088ThrSer: 2.088 ± 0.047	2.342ThrThr: 2.342 ± 0.07	4.13ThrVal: 4.13 ± 0.08	0.698ThrTrp: 0.698 ± 0.027	1.015ThrTyr: 1.015 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	9.686ValAla: 9.686 ± 0.125	0.614ValCys: 0.614 ± 0.024	4.45ValAsp: 4.45 ± 0.079	4.383ValGlu: 4.383 ± 0.076	2.732ValPhe: 2.732 ± 0.056	5.53ValGly: 5.53 ± 0.08	1.546ValHis: 1.546 ± 0.039	3.076ValIle: 3.076 ± 0.065	1.854ValLys: 1.854 ± 0.052	8.919ValLeu: 8.919 ± 0.112	1.59ValMet: 1.59 ± 0.039	1.89ValAsn: 1.89 ± 0.047	4.002ValPro: 4.002 ± 0.069	2.436ValGln: 2.436 ± 0.049	5.581ValArg: 5.581 ± 0.081	3.987ValSer: 3.987 ± 0.058	3.632ValThr: 3.632 ± 0.08	6.292ValVal: 6.292 ± 0.093	0.956ValTrp: 0.956 ± 0.034	1.565ValTyr: 1.565 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.35TrpAla: 1.35 ± 0.043	0.148TrpCys: 0.148 ± 0.012	0.643TrpAsp: 0.643 ± 0.027	0.555TrpGlu: 0.555 ± 0.024	0.624TrpPhe: 0.624 ± 0.027	0.958TrpGly: 0.958 ± 0.029	0.354TrpHis: 0.354 ± 0.023	0.669TrpIle: 0.669 ± 0.027	0.406TrpLys: 0.406 ± 0.02	2.386TrpLeu: 2.386 ± 0.061	0.353TrpMet: 0.353 ± 0.022	0.422TrpAsn: 0.422 ± 0.022	0.896TrpPro: 0.896 ± 0.031	0.655TrpGln: 0.655 ± 0.027	1.495TrpArg: 1.495 ± 0.053	0.872TrpSer: 0.872 ± 0.034	0.803TrpThr: 0.803 ± 0.034	1.003TrpVal: 1.003 ± 0.03	0.306TrpTrp: 0.306 ± 0.019	0.372TrpTyr: 0.372 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.777TyrAla: 2.777 ± 0.05	0.22TyrCys: 0.22 ± 0.014	1.405TyrAsp: 1.405 ± 0.081	1.173TyrGlu: 1.173 ± 0.037	0.907TyrPhe: 0.907 ± 0.03	2.137TyrGly: 2.137 ± 0.055	0.455TyrHis: 0.455 ± 0.023	0.61TyrIle: 0.61 ± 0.024	0.447TyrLys: 0.447 ± 0.022	2.48TyrLeu: 2.48 ± 0.051	0.354TyrMet: 0.354 ± 0.02	0.534TyrAsn: 0.534 ± 0.028	1.133TyrPro: 1.133 ± 0.035	0.789TyrGln: 0.789 ± 0.032	2.023TyrArg: 2.023 ± 0.046	1.224TyrSer: 1.224 ± 0.04	1.192TyrThr: 1.192 ± 0.044	1.584TyrVal: 1.584 ± 0.043	0.365TyrTrp: 0.365 ± 0.02	0.577TyrTyr: 0.577 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3016 proteins (1012916 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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