Amino acid dipepetide frequency for Auriculariopsis ampla

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.975AlaAla: 10.975 ± 0.068	1.399AlaCys: 1.399 ± 0.018	5.247AlaAsp: 5.247 ± 0.034	5.264AlaGlu: 5.264 ± 0.036	3.401AlaPhe: 3.401 ± 0.027	6.301AlaGly: 6.301 ± 0.039	2.594AlaHis: 2.594 ± 0.021	3.898AlaIle: 3.898 ± 0.029	3.718AlaLys: 3.718 ± 0.032	9.605AlaLeu: 9.605 ± 0.047	2.272AlaMet: 2.272 ± 0.021	2.652AlaAsn: 2.652 ± 0.02	6.786AlaPro: 6.786 ± 0.045	3.737AlaGln: 3.737 ± 0.028	7.03AlaArg: 7.03 ± 0.038	8.698AlaSer: 8.698 ± 0.054	5.829AlaThr: 5.829 ± 0.034	6.023AlaVal: 6.023 ± 0.036	1.324AlaTrp: 1.324 ± 0.015	2.547AlaTyr: 2.547 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	1.377CysAla: 1.377 ± 0.015	0.298CysCys: 0.298 ± 0.007	0.781CysAsp: 0.781 ± 0.012	0.677CysGlu: 0.677 ± 0.011	0.497CysPhe: 0.497 ± 0.011	1.014CysGly: 1.014 ± 0.014	0.372CysHis: 0.372 ± 0.007	0.686CysIle: 0.686 ± 0.011	0.516CysLys: 0.516 ± 0.008	1.337CysLeu: 1.337 ± 0.015	0.347CysMet: 0.347 ± 0.008	0.383CysAsn: 0.383 ± 0.008	0.914CysPro: 0.914 ± 0.014	0.441CysGln: 0.441 ± 0.009	1.018CysArg: 1.018 ± 0.015	1.121CysSer: 1.121 ± 0.015	0.882CysThr: 0.882 ± 0.014	0.951CysVal: 0.951 ± 0.013	0.231CysTrp: 0.231 ± 0.006	0.358CysTyr: 0.358 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	6.383AspAla: 6.383 ± 0.033	0.698AspCys: 0.698 ± 0.012	4.896AspAsp: 4.896 ± 0.042	4.708AspGlu: 4.708 ± 0.042	2.04AspPhe: 2.04 ± 0.02	4.293AspGly: 4.293 ± 0.034	1.253AspHis: 1.253 ± 0.016	2.909AspIle: 2.909 ± 0.023	2.025AspLys: 2.025 ± 0.024	5.09AspLeu: 5.09 ± 0.026	1.462AspMet: 1.462 ± 0.014	1.637AspAsn: 1.637 ± 0.017	3.33AspPro: 3.33 ± 0.023	1.486AspGln: 1.486 ± 0.015	3.139AspArg: 3.139 ± 0.025	3.839AspSer: 3.839 ± 0.032	3.087AspThr: 3.087 ± 0.028	4.457AspVal: 4.457 ± 0.028	0.89AspTrp: 0.89 ± 0.013	1.523AspTyr: 1.523 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.348GluAla: 5.348 ± 0.035	0.667GluCys: 0.667 ± 0.011	4.342GluAsp: 4.342 ± 0.036	5.171GluGlu: 5.171 ± 0.051	1.651GluPhe: 1.651 ± 0.017	3.834GluGly: 3.834 ± 0.026	1.514GluHis: 1.514 ± 0.016	2.363GluIle: 2.363 ± 0.021	2.652GluLys: 2.652 ± 0.026	5.109GluLeu: 5.109 ± 0.033	1.36GluMet: 1.36 ± 0.015	1.627GluAsn: 1.627 ± 0.015	2.77GluPro: 2.77 ± 0.026	2.219GluGln: 2.219 ± 0.024	4.332GluArg: 4.332 ± 0.034	3.588GluSer: 3.588 ± 0.027	2.882GluThr: 2.882 ± 0.021	3.509GluVal: 3.509 ± 0.026	0.873GluTrp: 0.873 ± 0.012	1.553GluTyr: 1.553 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.307PheAla: 3.307 ± 0.023	0.547PheCys: 0.547 ± 0.01	2.284PheAsp: 2.284 ± 0.02	1.808PheGlu: 1.808 ± 0.018	1.362PhePhe: 1.362 ± 0.019	2.471PheGly: 2.471 ± 0.026	0.84PheHis: 0.84 ± 0.012	1.508PheIle: 1.508 ± 0.019	1.217PheLys: 1.217 ± 0.015	3.073PheLeu: 3.073 ± 0.025	0.762PheMet: 0.762 ± 0.012	1.122PheAsn: 1.122 ± 0.014	1.994PhePro: 1.994 ± 0.02	1.023PheGln: 1.023 ± 0.015	1.911PheArg: 1.911 ± 0.02	2.653PheSer: 2.653 ± 0.023	1.979PheThr: 1.979 ± 0.02	2.47PheVal: 2.47 ± 0.022	0.529PheTrp: 0.529 ± 0.011	0.975PheTyr: 0.975 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	6.069GlyAla: 6.069 ± 0.041	0.92GlyCys: 0.92 ± 0.012	3.702GlyAsp: 3.702 ± 0.027	3.521GlyGlu: 3.521 ± 0.027	2.265GlyPhe: 2.265 ± 0.021	5.637GlyGly: 5.637 ± 0.066	1.684GlyHis: 1.684 ± 0.019	2.794GlyIle: 2.794 ± 0.023	2.988GlyLys: 2.988 ± 0.027	5.519GlyLeu: 5.519 ± 0.034	1.657GlyMet: 1.657 ± 0.021	1.89GlyAsn: 1.89 ± 0.02	3.391GlyPro: 3.391 ± 0.026	2.245GlyGln: 2.245 ± 0.022	4.629GlyArg: 4.629 ± 0.03	5.255GlySer: 5.255 ± 0.032	3.755GlyThr: 3.755 ± 0.027	4.313GlyVal: 4.313 ± 0.03	1.096GlyTrp: 1.096 ± 0.016	1.863GlyTyr: 1.863 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	2.624HisAla: 2.624 ± 0.021	0.444HisCys: 0.444 ± 0.008	1.485HisAsp: 1.485 ± 0.016	1.317HisGlu: 1.317 ± 0.014	0.916HisPhe: 0.916 ± 0.013	1.719HisGly: 1.719 ± 0.017	0.871HisHis: 0.871 ± 0.013	1.316HisIle: 1.316 ± 0.014	0.844HisLys: 0.844 ± 0.011	2.549HisLeu: 2.549 ± 0.024	0.518HisMet: 0.518 ± 0.009	0.747HisAsn: 0.747 ± 0.011	1.932HisPro: 1.932 ± 0.022	0.809HisGln: 0.809 ± 0.01	1.854HisArg: 1.854 ± 0.019	1.932HisSer: 1.932 ± 0.019	1.461HisThr: 1.461 ± 0.016	1.77HisVal: 1.77 ± 0.016	0.369HisTrp: 0.369 ± 0.008	0.67HisTyr: 0.67 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.104IleAla: 4.104 ± 0.027	0.745IleCys: 0.745 ± 0.012	2.625IleAsp: 2.625 ± 0.021	2.298IleGlu: 2.298 ± 0.02	1.611IlePhe: 1.611 ± 0.019	2.557IleGly: 2.557 ± 0.025	1.113IleHis: 1.113 ± 0.012	1.993IleIle: 1.993 ± 0.023	1.567IleLys: 1.567 ± 0.017	3.821IleLeu: 3.821 ± 0.033	0.949IleMet: 0.949 ± 0.013	1.285IleAsn: 1.285 ± 0.014	2.803IlePro: 2.803 ± 0.019	1.451IleGln: 1.451 ± 0.018	2.635IleArg: 2.635 ± 0.02	3.216IleSer: 3.216 ± 0.025	2.388IleThr: 2.388 ± 0.021	3.053IleVal: 3.053 ± 0.024	0.639IleTrp: 0.639 ± 0.01	1.182IleTyr: 1.182 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	3.964LysAla: 3.964 ± 0.034	0.454LysCys: 0.454 ± 0.009	2.325LysAsp: 2.325 ± 0.021	2.647LysGlu: 2.647 ± 0.025	1.088LysPhe: 1.088 ± 0.013	2.512LysGly: 2.512 ± 0.023	1.009LysHis: 1.009 ± 0.013	1.636LysIle: 1.636 ± 0.018	2.473LysLys: 2.473 ± 0.034	3.332LysLeu: 3.332 ± 0.027	0.842LysMet: 0.842 ± 0.012	1.22LysAsn: 1.22 ± 0.015	2.31LysPro: 2.31 ± 0.023	1.432LysGln: 1.432 ± 0.014	3.335LysArg: 3.335 ± 0.024	2.634LysSer: 2.634 ± 0.023	2.356LysThr: 2.356 ± 0.023	2.251LysVal: 2.251 ± 0.02	0.551LysTrp: 0.551 ± 0.01	1.111LysTyr: 1.111 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	8.899LeuAla: 8.899 ± 0.045	1.463LeuCys: 1.463 ± 0.017	5.387LeuAsp: 5.387 ± 0.031	5.153LeuGlu: 5.153 ± 0.036	3.088LeuPhe: 3.088 ± 0.03	5.335LeuGly: 5.335 ± 0.032	2.61LeuHis: 2.61 ± 0.023	3.331LeuIle: 3.331 ± 0.028	3.497LeuLys: 3.497 ± 0.028	8.516LeuLeu: 8.516 ± 0.05	1.796LeuMet: 1.796 ± 0.017	2.655LeuAsn: 2.655 ± 0.023	6.393LeuPro: 6.393 ± 0.037	3.601LeuGln: 3.601 ± 0.027	6.944LeuArg: 6.944 ± 0.038	7.432LeuSer: 7.432 ± 0.044	5.021LeuThr: 5.021 ± 0.033	5.682LeuVal: 5.682 ± 0.033	1.232LeuTrp: 1.232 ± 0.015	2.348LeuTyr: 2.348 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.085MetAla: 2.085 ± 0.021	0.291MetCys: 0.291 ± 0.006	1.366MetAsp: 1.366 ± 0.016	1.194MetGlu: 1.194 ± 0.014	0.746MetPhe: 0.746 ± 0.012	1.401MetGly: 1.401 ± 0.021	0.641MetHis: 0.641 ± 0.01	0.848MetIle: 0.848 ± 0.011	0.883MetLys: 0.883 ± 0.013	1.998MetLeu: 1.998 ± 0.019	0.586MetMet: 0.586 ± 0.011	0.732MetAsn: 0.732 ± 0.011	1.584MetPro: 1.584 ± 0.017	0.98MetGln: 0.98 ± 0.015	1.653MetArg: 1.653 ± 0.016	2.187MetSer: 2.187 ± 0.019	1.316MetThr: 1.316 ± 0.016	1.167MetVal: 1.167 ± 0.015	0.283MetTrp: 0.283 ± 0.006	0.62MetTyr: 0.62 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.127AsnAla: 3.127 ± 0.023	0.359AsnCys: 0.359 ± 0.008	1.641AsnAsp: 1.641 ± 0.017	1.542AsnGlu: 1.542 ± 0.016	1.066AsnPhe: 1.066 ± 0.015	2.294AsnGly: 2.294 ± 0.024	0.658AsnHis: 0.658 ± 0.009	1.549AsnIle: 1.549 ± 0.015	1.141AsnLys: 1.141 ± 0.014	2.573AsnLeu: 2.573 ± 0.022	0.744AsnMet: 0.744 ± 0.011	0.997AsnAsn: 0.997 ± 0.016	1.839AsnPro: 1.839 ± 0.018	0.828AsnGln: 0.828 ± 0.013	1.529AsnArg: 1.529 ± 0.017	2.045AsnSer: 2.045 ± 0.021	1.752AsnThr: 1.752 ± 0.017	2.186AsnVal: 2.186 ± 0.02	0.431AsnTrp: 0.431 ± 0.008	0.789AsnTyr: 0.789 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	6.988ProAla: 6.988 ± 0.043	0.722ProCys: 0.722 ± 0.011	3.416ProAsp: 3.416 ± 0.023	3.582ProGlu: 3.582 ± 0.026	2.075ProPhe: 2.075 ± 0.019	3.861ProGly: 3.861 ± 0.031	1.692ProHis: 1.692 ± 0.02	2.394ProIle: 2.394 ± 0.021	2.202ProLys: 2.202 ± 0.024	5.456ProLeu: 5.456 ± 0.034	1.288ProMet: 1.288 ± 0.017	1.837ProAsn: 1.837 ± 0.017	7.171ProPro: 7.171 ± 0.073	2.375ProGln: 2.375 ± 0.027	4.57ProArg: 4.57 ± 0.033	7.344ProSer: 7.344 ± 0.052	4.431ProThr: 4.431 ± 0.033	3.895ProVal: 3.895 ± 0.028	0.787ProTrp: 0.787 ± 0.012	1.69ProTyr: 1.69 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.516GlnAla: 3.516 ± 0.03	0.5GlnCys: 0.5 ± 0.009	1.903GlnAsp: 1.903 ± 0.018	2.062GlnGlu: 2.062 ± 0.02	1.055GlnPhe: 1.055 ± 0.014	2.042GlnGly: 2.042 ± 0.022	1.066GlnHis: 1.066 ± 0.014	1.449GlnIle: 1.449 ± 0.015	1.371GlnLys: 1.371 ± 0.018	3.238GlnLeu: 3.238 ± 0.029	0.845GlnMet: 0.845 ± 0.012	1.08GlnAsn: 1.08 ± 0.013	2.489GlnPro: 2.489 ± 0.03	1.985GlnGln: 1.985 ± 0.039	2.834GlnArg: 2.834 ± 0.026	2.676GlnSer: 2.676 ± 0.025	2.113GlnThr: 2.113 ± 0.02	1.962GlnVal: 1.962 ± 0.02	0.563GlnTrp: 0.563 ± 0.01	1.031GlnTyr: 1.031 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	6.941ArgAla: 6.941 ± 0.046	1.086ArgCys: 1.086 ± 0.017	3.724ArgAsp: 3.724 ± 0.029	3.999ArgGlu: 3.999 ± 0.031	2.133ArgPhe: 2.133 ± 0.02	4.225ArgGly: 4.225 ± 0.033	1.903ArgHis: 1.903 ± 0.017	2.867ArgIle: 2.867 ± 0.022	3.191ArgLys: 3.191 ± 0.028	6.456ArgLeu: 6.456 ± 0.04	1.619ArgMet: 1.619 ± 0.016	1.908ArgAsn: 1.908 ± 0.017	4.509ArgPro: 4.509 ± 0.036	2.672ArgGln: 2.672 ± 0.022	6.921ArgArg: 6.921 ± 0.052	5.543ArgSer: 5.543 ± 0.041	4.191ArgThr: 4.191 ± 0.03	4.221ArgVal: 4.221 ± 0.027	1.072ArgTrp: 1.072 ± 0.013	1.75ArgTyr: 1.75 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	8.115SerAla: 8.115 ± 0.054	1.048SerCys: 1.048 ± 0.016	4.351SerAsp: 4.351 ± 0.03	3.688SerGlu: 3.688 ± 0.027	2.782SerPhe: 2.782 ± 0.022	5.373SerGly: 5.373 ± 0.039	1.98SerHis: 1.98 ± 0.022	3.296SerIle: 3.296 ± 0.023	2.883SerLys: 2.883 ± 0.024	7.169SerLeu: 7.169 ± 0.045	1.818SerMet: 1.818 ± 0.017	2.209SerAsn: 2.209 ± 0.018	6.443SerPro: 6.443 ± 0.051	2.761SerGln: 2.761 ± 0.028	5.692SerArg: 5.692 ± 0.041	9.415SerSer: 9.415 ± 0.082	5.807SerThr: 5.807 ± 0.044	4.819SerVal: 4.819 ± 0.027	1.039SerTrp: 1.039 ± 0.013	1.962SerTyr: 1.962 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	5.637ThrAla: 5.637 ± 0.034	0.876ThrCys: 0.876 ± 0.014	2.907ThrAsp: 2.907 ± 0.023	2.724ThrGlu: 2.724 ± 0.022	2.161ThrPhe: 2.161 ± 0.019	3.732ThrGly: 3.732 ± 0.025	1.518ThrHis: 1.518 ± 0.014	2.666ThrIle: 2.666 ± 0.024	2.094ThrLys: 2.094 ± 0.021	5.696ThrLeu: 5.696 ± 0.032	1.329ThrMet: 1.329 ± 0.014	1.684ThrAsn: 1.684 ± 0.015	4.766ThrPro: 4.766 ± 0.036	1.894ThrGln: 1.894 ± 0.018	3.809ThrArg: 3.809 ± 0.03	5.562ThrSer: 5.562 ± 0.038	4.142ThrThr: 4.142 ± 0.033	3.842ThrVal: 3.842 ± 0.028	0.807ThrTrp: 0.807 ± 0.012	1.595ThrTyr: 1.595 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	6.046ValAla: 6.046 ± 0.037	1.019ValCys: 1.019 ± 0.014	4.141ValAsp: 4.141 ± 0.028	3.724ValGlu: 3.724 ± 0.029	2.402ValPhe: 2.402 ± 0.019	3.836ValGly: 3.836 ± 0.029	1.728ValHis: 1.728 ± 0.018	2.659ValIle: 2.659 ± 0.024	2.569ValLys: 2.569 ± 0.021	6.187ValLeu: 6.187 ± 0.034	1.34ValMet: 1.34 ± 0.014	1.971ValAsn: 1.971 ± 0.02	4.09ValPro: 4.09 ± 0.024	2.427ValGln: 2.427 ± 0.019	4.229ValArg: 4.229 ± 0.029	4.605ValSer: 4.605 ± 0.025	3.428ValThr: 3.428 ± 0.024	4.599ValVal: 4.599 ± 0.028	0.933ValTrp: 0.933 ± 0.016	1.835ValTyr: 1.835 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	1.221TrpAla: 1.221 ± 0.016	0.206TrpCys: 0.206 ± 0.005	0.878TrpAsp: 0.878 ± 0.013	0.822TrpGlu: 0.822 ± 0.01	0.493TrpPhe: 0.493 ± 0.009	0.84TrpGly: 0.84 ± 0.013	0.375TrpHis: 0.375 ± 0.008	0.638TrpIle: 0.638 ± 0.011	0.691TrpLys: 0.691 ± 0.011	1.289TrpLeu: 1.289 ± 0.014	0.387TrpMet: 0.387 ± 0.009	0.514TrpAsn: 0.514 ± 0.01	0.702TrpPro: 0.702 ± 0.012	0.544TrpGln: 0.544 ± 0.01	1.184TrpArg: 1.184 ± 0.014	1.04TrpSer: 1.04 ± 0.013	0.964TrpThr: 0.964 ± 0.012	0.84TrpVal: 0.84 ± 0.013	0.261TrpTrp: 0.261 ± 0.007	0.401TrpTyr: 0.401 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.578TyrAla: 2.578 ± 0.023	0.457TyrCys: 0.457 ± 0.009	1.745TyrAsp: 1.745 ± 0.016	1.462TyrGlu: 1.462 ± 0.017	1.006TyrPhe: 1.006 ± 0.013	1.917TyrGly: 1.917 ± 0.02	0.727TyrHis: 0.727 ± 0.008	1.233TyrIle: 1.233 ± 0.015	0.961TyrLys: 0.961 ± 0.016	2.371TyrLeu: 2.371 ± 0.022	0.638TyrMet: 0.638 ± 0.012	0.942TyrAsn: 0.942 ± 0.013	1.557TyrPro: 1.557 ± 0.018	0.869TyrGln: 0.869 ± 0.013	1.68TyrArg: 1.68 ± 0.017	1.866TyrSer: 1.866 ± 0.02	1.658TyrThr: 1.658 ± 0.014	1.758TyrVal: 1.758 ± 0.017	0.379TyrTrp: 0.379 ± 0.008	0.828TyrTyr: 0.828 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 15404 proteins (6453724 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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