Amino acid dipepetide frequency for Alkalilimnicola ehrlichii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.013AlaAla: 14.013 ± 0.149	1.15AlaCys: 1.15 ± 0.034	6.132AlaAsp: 6.132 ± 0.086	8.334AlaGlu: 8.334 ± 0.088	3.766AlaPhe: 3.766 ± 0.063	9.276AlaGly: 9.276 ± 0.128	2.257AlaHis: 2.257 ± 0.042	5.381AlaIle: 5.381 ± 0.074	2.988AlaLys: 2.988 ± 0.053	13.12AlaLeu: 13.12 ± 0.127	2.592AlaMet: 2.592 ± 0.049	2.889AlaAsn: 2.889 ± 0.05	4.515AlaPro: 4.515 ± 0.074	4.309AlaGln: 4.309 ± 0.076	7.65AlaArg: 7.65 ± 0.089	5.827AlaSer: 5.827 ± 0.081	5.165AlaThr: 5.165 ± 0.069	8.572AlaVal: 8.572 ± 0.1	1.548AlaTrp: 1.548 ± 0.039	2.974AlaTyr: 2.974 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	0.928CysAla: 0.928 ± 0.031	0.155CysCys: 0.155 ± 0.01	0.47CysAsp: 0.47 ± 0.02	0.575CysGlu: 0.575 ± 0.022	0.336CysPhe: 0.336 ± 0.019	0.867CysGly: 0.867 ± 0.027	0.257CysHis: 0.257 ± 0.014	0.383CysIle: 0.383 ± 0.019	0.204CysLys: 0.204 ± 0.014	1.044CysLeu: 1.044 ± 0.036	0.186CysMet: 0.186 ± 0.011	0.212CysAsn: 0.212 ± 0.013	0.478CysPro: 0.478 ± 0.02	0.326CysGln: 0.326 ± 0.017	0.833CysArg: 0.833 ± 0.028	0.54CysSer: 0.54 ± 0.022	0.412CysThr: 0.412 ± 0.019	0.611CysVal: 0.611 ± 0.024	0.138CysTrp: 0.138 ± 0.011	0.252CysTyr: 0.252 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	5.899AspAla: 5.899 ± 0.078	0.535AspCys: 0.535 ± 0.021	3.351AspAsp: 3.351 ± 0.067	3.897AspGlu: 3.897 ± 0.063	2.086AspPhe: 2.086 ± 0.038	4.546AspGly: 4.546 ± 0.087	1.108AspHis: 1.108 ± 0.034	2.984AspIle: 2.984 ± 0.055	1.545AspLys: 1.545 ± 0.04	5.591AspLeu: 5.591 ± 0.073	1.188AspMet: 1.188 ± 0.029	1.731AspAsn: 1.731 ± 0.045	2.926AspPro: 2.926 ± 0.057	1.78AspGln: 1.78 ± 0.042	3.958AspArg: 3.958 ± 0.056	2.796AspSer: 2.796 ± 0.053	2.742AspThr: 2.742 ± 0.054	3.842AspVal: 3.842 ± 0.06	1.0AspTrp: 1.0 ± 0.032	1.911AspTyr: 1.911 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	7.964GluAla: 7.964 ± 0.097	0.425GluCys: 0.425 ± 0.019	2.954GluAsp: 2.954 ± 0.054	4.289GluGlu: 4.289 ± 0.087	2.003GluPhe: 2.003 ± 0.047	4.478GluGly: 4.478 ± 0.059	1.833GluHis: 1.833 ± 0.039	3.046GluIle: 3.046 ± 0.052	1.793GluLys: 1.793 ± 0.041	7.679GluLeu: 7.679 ± 0.095	1.377GluMet: 1.377 ± 0.036	1.557GluAsn: 1.557 ± 0.039	3.246GluPro: 3.246 ± 0.07	3.972GluGln: 3.972 ± 0.068	6.569GluArg: 6.569 ± 0.08	3.017GluSer: 3.017 ± 0.056	3.273GluThr: 3.273 ± 0.057	4.845GluVal: 4.845 ± 0.071	0.885GluTrp: 0.885 ± 0.026	1.554GluTyr: 1.554 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.807PheAla: 3.807 ± 0.072	0.421PheCys: 0.421 ± 0.019	2.413PheAsp: 2.413 ± 0.046	2.222PheGlu: 2.222 ± 0.044	1.351PhePhe: 1.351 ± 0.041	3.196PheGly: 3.196 ± 0.053	0.795PheHis: 0.795 ± 0.029	1.656PheIle: 1.656 ± 0.039	0.854PheLys: 0.854 ± 0.029	3.365PheLeu: 3.365 ± 0.056	0.787PheMet: 0.787 ± 0.027	1.072PheAsn: 1.072 ± 0.031	1.498PhePro: 1.498 ± 0.04	1.153PheGln: 1.153 ± 0.034	2.332PheArg: 2.332 ± 0.05	2.416PheSer: 2.416 ± 0.042	1.778PheThr: 1.778 ± 0.039	2.629PheVal: 2.629 ± 0.052	0.541PheTrp: 0.541 ± 0.025	1.037PheTyr: 1.037 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	7.618GlyAla: 7.618 ± 0.095	0.87GlyCys: 0.87 ± 0.031	4.257GlyAsp: 4.257 ± 0.07	5.489GlyGlu: 5.489 ± 0.075	3.246GlyPhe: 3.246 ± 0.049	6.483GlyGly: 6.483 ± 0.11	1.852GlyHis: 1.852 ± 0.037	4.055GlyIle: 4.055 ± 0.062	2.511GlyLys: 2.511 ± 0.049	8.462GlyLeu: 8.462 ± 0.098	1.997GlyMet: 1.997 ± 0.046	2.37GlyAsn: 2.37 ± 0.052	2.806GlyPro: 2.806 ± 0.052	2.999GlyGln: 2.999 ± 0.056	6.091GlyArg: 6.091 ± 0.07	4.547GlySer: 4.547 ± 0.072	3.878GlyThr: 3.878 ± 0.065	6.031GlyVal: 6.031 ± 0.091	1.296GlyTrp: 1.296 ± 0.031	2.467GlyTyr: 2.467 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.245HisAla: 2.245 ± 0.048	0.302HisCys: 0.302 ± 0.015	1.248HisAsp: 1.248 ± 0.031	1.346HisGlu: 1.346 ± 0.035	0.891HisPhe: 0.891 ± 0.028	1.989HisGly: 1.989 ± 0.044	0.626HisHis: 0.626 ± 0.029	1.062HisIle: 1.062 ± 0.03	0.515HisLys: 0.515 ± 0.022	2.353HisLeu: 2.353 ± 0.046	0.494HisMet: 0.494 ± 0.019	0.644HisAsn: 0.644 ± 0.027	1.376HisPro: 1.376 ± 0.034	0.788HisGln: 0.788 ± 0.031	1.899HisArg: 1.899 ± 0.038	1.199HisSer: 1.199 ± 0.029	1.055HisThr: 1.055 ± 0.029	1.485HisVal: 1.485 ± 0.036	0.445HisTrp: 0.445 ± 0.021	0.829HisTyr: 0.829 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.739IleAla: 5.739 ± 0.076	0.426IleCys: 0.426 ± 0.019	3.387IleAsp: 3.387 ± 0.059	3.572IleGlu: 3.572 ± 0.056	1.392IlePhe: 1.392 ± 0.037	4.324IleGly: 4.324 ± 0.064	0.951IleHis: 0.951 ± 0.029	1.934IleIle: 1.934 ± 0.046	1.356IleLys: 1.356 ± 0.034	4.056IleLeu: 4.056 ± 0.067	0.809IleMet: 0.809 ± 0.026	1.583IleAsn: 1.583 ± 0.036	2.36IlePro: 2.36 ± 0.046	1.523IleGln: 1.523 ± 0.031	3.36IleArg: 3.36 ± 0.057	2.652IleSer: 2.652 ± 0.046	2.357IleThr: 2.357 ± 0.045	3.575IleVal: 3.575 ± 0.055	0.516IleTrp: 0.516 ± 0.024	1.18IleTyr: 1.18 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	3.168LysAla: 3.168 ± 0.062	0.156LysCys: 0.156 ± 0.011	1.373LysAsp: 1.373 ± 0.041	1.62LysGlu: 1.62 ± 0.043	0.579LysPhe: 0.579 ± 0.022	1.904LysGly: 1.904 ± 0.049	0.691LysHis: 0.691 ± 0.025	1.194LysIle: 1.194 ± 0.038	0.863LysLys: 0.863 ± 0.031	2.818LysLeu: 2.818 ± 0.055	0.511LysMet: 0.511 ± 0.021	0.687LysAsn: 0.687 ± 0.027	1.698LysPro: 1.698 ± 0.046	1.292LysGln: 1.292 ± 0.035	2.448LysArg: 2.448 ± 0.05	1.266LysSer: 1.266 ± 0.032	1.442LysThr: 1.442 ± 0.038	2.006LysVal: 2.006 ± 0.046	0.26LysTrp: 0.26 ± 0.014	0.529LysTyr: 0.529 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	13.585LeuAla: 13.585 ± 0.131	0.961LeuCys: 0.961 ± 0.032	6.216LeuAsp: 6.216 ± 0.083	7.035LeuGlu: 7.035 ± 0.094	3.881LeuPhe: 3.881 ± 0.062	8.371LeuGly: 8.371 ± 0.094	2.319LeuHis: 2.319 ± 0.056	5.149LeuIle: 5.149 ± 0.08	3.01LeuLys: 3.01 ± 0.059	12.309LeuLeu: 12.309 ± 0.154	2.169LeuMet: 2.169 ± 0.043	3.18LeuAsn: 3.18 ± 0.061	5.95LeuPro: 5.95 ± 0.084	4.135LeuGln: 4.135 ± 0.069	8.255LeuArg: 8.255 ± 0.095	6.758LeuSer: 6.758 ± 0.076	5.731LeuThr: 5.731 ± 0.074	7.464LeuVal: 7.464 ± 0.096	1.35LeuTrp: 1.35 ± 0.038	2.644LeuTyr: 2.644 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.529MetAla: 2.529 ± 0.053	0.138MetCys: 0.138 ± 0.011	1.033MetAsp: 1.033 ± 0.031	1.205MetGlu: 1.205 ± 0.036	0.601MetPhe: 0.601 ± 0.023	1.458MetGly: 1.458 ± 0.037	0.444MetHis: 0.444 ± 0.022	0.976MetIle: 0.976 ± 0.028	0.728MetLys: 0.728 ± 0.029	2.418MetLeu: 2.418 ± 0.044	0.474MetMet: 0.474 ± 0.023	0.727MetAsn: 0.727 ± 0.026	1.267MetPro: 1.267 ± 0.029	0.946MetGln: 0.946 ± 0.029	1.668MetArg: 1.668 ± 0.035	1.494MetSer: 1.494 ± 0.036	1.3MetThr: 1.3 ± 0.037	1.425MetVal: 1.425 ± 0.034	0.151MetTrp: 0.151 ± 0.011	0.386MetTyr: 0.386 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.044AsnAla: 3.044 ± 0.053	0.271AsnCys: 0.271 ± 0.017	1.62AsnAsp: 1.62 ± 0.038	1.664AsnGlu: 1.664 ± 0.04	0.92AsnPhe: 0.92 ± 0.031	2.441AsnGly: 2.441 ± 0.052	0.603AsnHis: 0.603 ± 0.022	1.43AsnIle: 1.43 ± 0.036	0.744AsnLys: 0.744 ± 0.027	2.926AsnLeu: 2.926 ± 0.047	0.55AsnMet: 0.55 ± 0.021	0.963AsnAsn: 0.963 ± 0.036	1.83AsnPro: 1.83 ± 0.042	1.062AsnGln: 1.062 ± 0.03	2.252AsnArg: 2.252 ± 0.045	1.366AsnSer: 1.366 ± 0.036	1.43AsnThr: 1.43 ± 0.044	2.017AsnVal: 2.017 ± 0.046	0.439AsnTrp: 0.439 ± 0.019	0.804AsnTyr: 0.804 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	5.334ProAla: 5.334 ± 0.08	0.336ProCys: 0.336 ± 0.017	3.117ProAsp: 3.117 ± 0.054	4.116ProGlu: 4.116 ± 0.067	1.726ProPhe: 1.726 ± 0.039	3.866ProGly: 3.866 ± 0.07	1.04ProHis: 1.04 ± 0.032	2.179ProIle: 2.179 ± 0.04	1.286ProLys: 1.286 ± 0.039	5.273ProLeu: 5.273 ± 0.075	1.088ProMet: 1.088 ± 0.029	1.448ProAsn: 1.448 ± 0.038	2.503ProPro: 2.503 ± 0.057	1.919ProGln: 1.919 ± 0.041	3.024ProArg: 3.024 ± 0.051	2.682ProSer: 2.682 ± 0.046	2.301ProThr: 2.301 ± 0.047	3.92ProVal: 3.92 ± 0.065	0.711ProTrp: 0.711 ± 0.025	1.27ProTyr: 1.27 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	5.483GlnAla: 5.483 ± 0.087	0.267GlnCys: 0.267 ± 0.015	1.695GlnAsp: 1.695 ± 0.039	2.495GlnGlu: 2.495 ± 0.052	1.218GlnPhe: 1.218 ± 0.029	3.034GlnGly: 3.034 ± 0.053	1.037GlnHis: 1.037 ± 0.027	1.693GlnIle: 1.693 ± 0.039	0.873GlnLys: 0.873 ± 0.03	4.562GlnLeu: 4.562 ± 0.069	0.791GlnMet: 0.791 ± 0.027	0.903GlnAsn: 0.903 ± 0.027	2.089GlnPro: 2.089 ± 0.048	2.2GlnGln: 2.2 ± 0.055	3.694GlnArg: 3.694 ± 0.068	1.833GlnSer: 1.833 ± 0.038	2.002GlnThr: 2.002 ± 0.045	2.906GlnVal: 2.906 ± 0.049	0.58GlnTrp: 0.58 ± 0.021	0.9GlnTyr: 0.9 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	7.137ArgAla: 7.137 ± 0.084	0.728ArgCys: 0.728 ± 0.029	4.138ArgAsp: 4.138 ± 0.064	5.259ArgGlu: 5.259 ± 0.069	3.299ArgPhe: 3.299 ± 0.053	4.743ArgGly: 4.743 ± 0.072	2.104ArgHis: 2.104 ± 0.047	4.004ArgIle: 4.004 ± 0.056	2.062ArgLys: 2.062 ± 0.049	9.533ArgLeu: 9.533 ± 0.113	1.765ArgMet: 1.765 ± 0.041	2.2ArgAsn: 2.2 ± 0.042	3.406ArgPro: 3.406 ± 0.055	3.667ArgGln: 3.667 ± 0.066	6.516ArgArg: 6.516 ± 0.102	4.041ArgSer: 4.041 ± 0.061	3.324ArgThr: 3.324 ± 0.056	5.246ArgVal: 5.246 ± 0.077	1.334ArgTrp: 1.334 ± 0.028	2.703ArgTyr: 2.703 ± 0.055	0.0ArgXaa: 0.0 ± 0.0
Ser	5.945SerAla: 5.945 ± 0.072	0.507SerCys: 0.507 ± 0.022	2.883SerAsp: 2.883 ± 0.053	3.397SerGlu: 3.397 ± 0.053	2.061SerPhe: 2.061 ± 0.043	5.194SerGly: 5.194 ± 0.077	1.246SerHis: 1.246 ± 0.031	2.512SerIle: 2.512 ± 0.049	1.328SerLys: 1.328 ± 0.033	6.034SerLeu: 6.034 ± 0.069	1.301SerMet: 1.301 ± 0.036	1.572SerAsn: 1.572 ± 0.037	2.691SerPro: 2.691 ± 0.051	2.013SerGln: 2.013 ± 0.043	4.088SerArg: 4.088 ± 0.067	3.071SerSer: 3.071 ± 0.059	2.524SerThr: 2.524 ± 0.052	3.972SerVal: 3.972 ± 0.057	0.785SerTrp: 0.785 ± 0.027	1.445SerTyr: 1.445 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	5.679ThrAla: 5.679 ± 0.081	0.417ThrCys: 0.417 ± 0.02	2.68ThrAsp: 2.68 ± 0.052	2.943ThrGlu: 2.943 ± 0.048	1.612ThrPhe: 1.612 ± 0.035	4.336ThrGly: 4.336 ± 0.062	1.073ThrHis: 1.073 ± 0.032	2.126ThrIle: 2.126 ± 0.049	1.043ThrLys: 1.043 ± 0.028	5.927ThrLeu: 5.927 ± 0.076	0.894ThrMet: 0.894 ± 0.031	1.204ThrAsn: 1.204 ± 0.032	3.041ThrPro: 3.041 ± 0.054	1.742ThrGln: 1.742 ± 0.04	3.211ThrArg: 3.211 ± 0.058	2.413ThrSer: 2.413 ± 0.05	2.501ThrThr: 2.501 ± 0.048	4.296ThrVal: 4.296 ± 0.064	0.614ThrTrp: 0.614 ± 0.024	1.185ThrTyr: 1.185 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	8.531ValAla: 8.531 ± 0.107	0.684ValCys: 0.684 ± 0.027	4.306ValAsp: 4.306 ± 0.066	4.967ValGlu: 4.967 ± 0.075	2.73ValPhe: 2.73 ± 0.05	5.614ValGly: 5.614 ± 0.074	1.496ValHis: 1.496 ± 0.036	3.53ValIle: 3.53 ± 0.055	1.848ValLys: 1.848 ± 0.049	7.796ValLeu: 7.796 ± 0.091	1.591ValMet: 1.591 ± 0.032	2.281ValAsn: 2.281 ± 0.049	3.449ValPro: 3.449 ± 0.063	2.365ValGln: 2.365 ± 0.046	5.306ValArg: 5.306 ± 0.074	4.393ValSer: 4.393 ± 0.066	3.828ValThr: 3.828 ± 0.063	5.858ValVal: 5.858 ± 0.09	0.951ValTrp: 0.951 ± 0.033	1.873ValTyr: 1.873 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.203TrpAla: 1.203 ± 0.031	0.145TrpCys: 0.145 ± 0.011	0.641TrpAsp: 0.641 ± 0.023	0.787TrpGlu: 0.787 ± 0.024	0.573TrpPhe: 0.573 ± 0.023	0.958TrpGly: 0.958 ± 0.032	0.387TrpHis: 0.387 ± 0.018	0.625TrpIle: 0.625 ± 0.024	0.349TrpLys: 0.349 ± 0.018	2.079TrpLeu: 2.079 ± 0.051	0.319TrpMet: 0.319 ± 0.016	0.425TrpAsn: 0.425 ± 0.021	0.646TrpPro: 0.646 ± 0.024	0.85TrpGln: 0.85 ± 0.034	1.316TrpArg: 1.316 ± 0.036	0.78TrpSer: 0.78 ± 0.028	0.598TrpThr: 0.598 ± 0.022	0.976TrpVal: 0.976 ± 0.029	0.261TrpTrp: 0.261 ± 0.014	0.373TrpTyr: 0.373 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.604TyrAla: 2.604 ± 0.049	0.312TyrCys: 0.312 ± 0.016	1.505TyrAsp: 1.505 ± 0.04	1.549TyrGlu: 1.549 ± 0.041	1.053TyrPhe: 1.053 ± 0.03	2.25TyrGly: 2.25 ± 0.044	0.672TyrHis: 0.672 ± 0.023	1.132TyrIle: 1.132 ± 0.031	0.606TyrLys: 0.606 ± 0.02	3.125TyrLeu: 3.125 ± 0.05	0.484TyrMet: 0.484 ± 0.021	0.728TyrAsn: 0.728 ± 0.025	1.365TyrPro: 1.365 ± 0.037	1.213TyrGln: 1.213 ± 0.031	2.739TyrArg: 2.739 ± 0.052	1.478TyrSer: 1.478 ± 0.038	1.295TyrThr: 1.295 ± 0.039	1.721TyrVal: 1.721 ± 0.037	0.485TyrTrp: 0.485 ± 0.023	0.837TyrTyr: 0.837 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3993 proteins (1197236 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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