Amino acid dipepetide frequency for Tibrogargan virus (strain CS132) (TIBV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.941AlaAla: 0.941 ± 0.412
0.941AlaCys: 0.941 ± 0.587
2.822AlaAsp: 2.822 ± 0.573
0.706AlaGlu: 0.706 ± 0.308
2.117AlaPhe: 2.117 ± 0.514
0.47AlaGly: 0.47 ± 0.404
1.176AlaHis: 1.176 ± 0.372
2.352AlaIle: 2.352 ± 0.571
1.411AlaLys: 1.411 ± 0.737
3.293AlaLeu: 3.293 ± 0.994
0.706AlaMet: 0.706 ± 0.36
2.352AlaAsn: 2.352 ± 0.915
1.411AlaPro: 1.411 ± 1.115
1.176AlaGln: 1.176 ± 0.275
1.176AlaArg: 1.176 ± 0.608
3.057AlaSer: 3.057 ± 1.082
2.117AlaThr: 2.117 ± 0.794
1.411AlaVal: 1.411 ± 0.52
0.706AlaTrp: 0.706 ± 0.329
1.176AlaTyr: 1.176 ± 0.529
0.0AlaXaa: 0.0 ± 0.0
Cys
0.706CysAla: 0.706 ± 0.42
0.235CysCys: 0.235 ± 0.14
1.411CysAsp: 1.411 ± 0.384
1.646CysGlu: 1.646 ± 0.45
0.941CysPhe: 0.941 ± 0.325
0.47CysGly: 0.47 ± 0.404
0.706CysHis: 0.706 ± 0.606
1.176CysIle: 1.176 ± 0.384
2.117CysLys: 2.117 ± 0.518
3.528CysLeu: 3.528 ± 0.741
0.235CysMet: 0.235 ± 0.332
1.176CysAsn: 1.176 ± 0.496
0.706CysPro: 0.706 ± 0.332
1.646CysGln: 1.646 ± 0.482
0.941CysArg: 0.941 ± 0.588
1.176CysSer: 1.176 ± 0.52
0.706CysThr: 0.706 ± 0.34
0.706CysVal: 0.706 ± 0.242
0.47CysTrp: 0.47 ± 0.28
1.646CysTyr: 1.646 ± 0.509
0.0CysXaa: 0.0 ± 0.0
Asp
1.646AspAla: 1.646 ± 0.515
1.646AspCys: 1.646 ± 0.484
5.174AspAsp: 5.174 ± 1.719
2.822AspGlu: 2.822 ± 0.849
3.057AspPhe: 3.057 ± 0.655
2.587AspGly: 2.587 ± 0.974
1.646AspHis: 1.646 ± 0.372
3.528AspIle: 3.528 ± 0.987
3.528AspLys: 3.528 ± 0.808
7.996AspLeu: 7.996 ± 0.841
2.587AspMet: 2.587 ± 0.702
4.704AspAsn: 4.704 ± 1.039
3.057AspPro: 3.057 ± 0.601
2.822AspGln: 2.822 ± 1.157
1.411AspArg: 1.411 ± 0.416
5.644AspSer: 5.644 ± 1.389
3.057AspThr: 3.057 ± 0.596
2.822AspVal: 2.822 ± 0.937
1.176AspTrp: 1.176 ± 0.722
3.998AspTyr: 3.998 ± 0.459
0.0AspXaa: 0.0 ± 0.0
Glu
1.176GluAla: 1.176 ± 0.718
1.646GluCys: 1.646 ± 0.413
3.763GluAsp: 3.763 ± 0.722
3.763GluGlu: 3.763 ± 0.846
3.057GluPhe: 3.057 ± 0.86
2.117GluGly: 2.117 ± 0.627
1.411GluHis: 1.411 ± 0.69
4.939GluIle: 4.939 ± 1.094
3.763GluLys: 3.763 ± 1.412
5.644GluLeu: 5.644 ± 1.594
1.176GluMet: 1.176 ± 0.438
3.998GluAsn: 3.998 ± 0.815
2.117GluPro: 2.117 ± 0.5
0.941GluGln: 0.941 ± 0.428
1.646GluArg: 1.646 ± 0.452
3.528GluSer: 3.528 ± 0.961
2.822GluThr: 2.822 ± 0.969
2.352GluVal: 2.352 ± 0.957
0.235GluTrp: 0.235 ± 0.14
0.47GluTyr: 0.47 ± 0.28
0.0GluXaa: 0.0 ± 0.0
Phe
2.117PheAla: 2.117 ± 0.418
0.706PheCys: 0.706 ± 0.498
1.881PheAsp: 1.881 ± 0.984
2.117PheGlu: 2.117 ± 0.31
2.352PhePhe: 2.352 ± 0.68
1.411PheGly: 1.411 ± 0.658
1.176PheHis: 1.176 ± 0.752
1.411PheIle: 1.411 ± 0.657
4.939PheLys: 4.939 ± 1.217
3.763PheLeu: 3.763 ± 1.17
0.47PheMet: 0.47 ± 0.248
2.587PheAsn: 2.587 ± 0.852
1.411PhePro: 1.411 ± 0.996
2.352PheGln: 2.352 ± 0.877
2.117PheArg: 2.117 ± 0.865
3.293PheSer: 3.293 ± 0.972
1.881PheThr: 1.881 ± 0.426
3.528PheVal: 3.528 ± 0.394
0.706PheTrp: 0.706 ± 0.339
3.763PheTyr: 3.763 ± 1.042
0.0PheXaa: 0.0 ± 0.0
Gly
0.706GlyAla: 0.706 ± 0.242
0.235GlyCys: 0.235 ± 0.284
2.587GlyAsp: 2.587 ± 0.799
2.117GlyGlu: 2.117 ± 0.88
2.587GlyPhe: 2.587 ± 0.295
3.528GlyGly: 3.528 ± 0.717
1.176GlyHis: 1.176 ± 0.352
3.293GlyIle: 3.293 ± 0.583
3.057GlyLys: 3.057 ± 0.796
7.291GlyLeu: 7.291 ± 1.099
0.706GlyMet: 0.706 ± 0.398
2.587GlyAsn: 2.587 ± 0.545
1.176GlyPro: 1.176 ± 0.493
2.352GlyGln: 2.352 ± 0.724
0.941GlyArg: 0.941 ± 0.325
4.939GlySer: 4.939 ± 1.486
3.057GlyThr: 3.057 ± 0.992
2.587GlyVal: 2.587 ± 1.16
0.706GlyTrp: 0.706 ± 0.242
2.352GlyTyr: 2.352 ± 0.543
0.0GlyXaa: 0.0 ± 0.0
His
0.941HisAla: 0.941 ± 0.588
0.706HisCys: 0.706 ± 0.329
1.411HisAsp: 1.411 ± 0.545
1.411HisGlu: 1.411 ± 0.69
1.176HisPhe: 1.176 ± 0.447
0.941HisGly: 0.941 ± 0.772
0.47HisHis: 0.47 ± 0.421
2.352HisIle: 2.352 ± 1.248
2.352HisLys: 2.352 ± 0.703
3.057HisLeu: 3.057 ± 0.871
0.47HisMet: 0.47 ± 0.294
1.646HisAsn: 1.646 ± 0.437
2.352HisPro: 2.352 ± 1.095
0.706HisGln: 0.706 ± 0.355
1.176HisArg: 1.176 ± 0.288
2.117HisSer: 2.117 ± 0.813
0.706HisThr: 0.706 ± 0.339
1.646HisVal: 1.646 ± 0.964
0.706HisTrp: 0.706 ± 0.339
0.47HisTyr: 0.47 ± 0.28
0.0HisXaa: 0.0 ± 0.0
Ile
2.117IleAla: 2.117 ± 0.7
2.822IleCys: 2.822 ± 0.888
2.822IleAsp: 2.822 ± 0.879
3.528IleGlu: 3.528 ± 1.074
3.057IlePhe: 3.057 ± 1.253
5.174IleGly: 5.174 ± 1.032
2.117IleHis: 2.117 ± 0.871
8.467IleIle: 8.467 ± 1.472
9.878IleLys: 9.878 ± 1.155
5.88IleLeu: 5.88 ± 0.727
1.646IleMet: 1.646 ± 0.589
5.644IleAsn: 5.644 ± 0.679
3.293IlePro: 3.293 ± 0.98
2.822IleGln: 2.822 ± 0.778
4.468IleArg: 4.468 ± 0.755
8.467IleSer: 8.467 ± 0.857
3.293IleThr: 3.293 ± 1.447
1.881IleVal: 1.881 ± 0.586
1.176IleTrp: 1.176 ± 0.606
3.763IleTyr: 3.763 ± 1.009
0.0IleXaa: 0.0 ± 0.0
Lys
1.881LysAla: 1.881 ± 0.996
1.411LysCys: 1.411 ± 0.511
4.939LysAsp: 4.939 ± 1.583
4.233LysGlu: 4.233 ± 1.038
1.881LysPhe: 1.881 ± 0.899
4.468LysGly: 4.468 ± 1.096
1.881LysHis: 1.881 ± 1.024
7.526LysIle: 7.526 ± 1.483
5.644LysLys: 5.644 ± 0.938
8.231LysLeu: 8.231 ± 1.812
1.411LysMet: 1.411 ± 0.71
4.939LysAsn: 4.939 ± 0.837
3.057LysPro: 3.057 ± 0.605
2.587LysGln: 2.587 ± 0.694
2.822LysArg: 2.822 ± 0.645
3.293LysSer: 3.293 ± 0.65
3.763LysThr: 3.763 ± 0.889
4.704LysVal: 4.704 ± 1.232
1.411LysTrp: 1.411 ± 0.677
3.057LysTyr: 3.057 ± 0.867
0.0LysXaa: 0.0 ± 0.0
Leu
4.233LeuAla: 4.233 ± 0.595
2.117LeuCys: 2.117 ± 0.629
7.761LeuAsp: 7.761 ± 1.138
5.409LeuGlu: 5.409 ± 0.878
3.998LeuPhe: 3.998 ± 0.981
4.704LeuGly: 4.704 ± 1.058
1.646LeuHis: 1.646 ± 0.25
9.878LeuIle: 9.878 ± 2.212
7.291LeuLys: 7.291 ± 1.549
7.526LeuLeu: 7.526 ± 1.011
3.293LeuMet: 3.293 ± 0.662
6.585LeuAsn: 6.585 ± 1.236
3.528LeuPro: 3.528 ± 0.931
3.057LeuGln: 3.057 ± 0.955
5.88LeuArg: 5.88 ± 1.187
7.761LeuSer: 7.761 ± 1.54
6.585LeuThr: 6.585 ± 1.606
6.35LeuVal: 6.35 ± 0.853
0.235LeuTrp: 0.235 ± 0.288
3.057LeuTyr: 3.057 ± 0.451
0.0LeuXaa: 0.0 ± 0.0
Met
1.176MetAla: 1.176 ± 0.404
0.706MetCys: 0.706 ± 0.649
1.411MetAsp: 1.411 ± 0.44
2.117MetGlu: 2.117 ± 0.891
1.411MetPhe: 1.411 ± 0.727
0.706MetGly: 0.706 ± 0.346
0.941MetHis: 0.941 ± 0.587
3.293MetIle: 3.293 ± 1.009
2.117MetLys: 2.117 ± 1.188
2.352MetLeu: 2.352 ± 0.983
1.411MetMet: 1.411 ± 0.615
0.941MetAsn: 0.941 ± 0.412
0.47MetPro: 0.47 ± 0.286
0.0MetGln: 0.0 ± 0.0
0.941MetArg: 0.941 ± 0.351
1.411MetSer: 1.411 ± 0.376
1.646MetThr: 1.646 ± 0.556
0.706MetVal: 0.706 ± 0.423
0.0MetTrp: 0.0 ± 0.0
0.235MetTyr: 0.235 ± 0.317
0.0MetXaa: 0.0 ± 0.0
Asn
2.822AsnAla: 2.822 ± 0.526
1.646AsnCys: 1.646 ± 0.556
3.528AsnAsp: 3.528 ± 0.486
4.468AsnGlu: 4.468 ± 0.793
3.057AsnPhe: 3.057 ± 0.766
3.528AsnGly: 3.528 ± 0.766
0.941AsnHis: 0.941 ± 0.325
5.409AsnIle: 5.409 ± 0.875
3.528AsnLys: 3.528 ± 1.043
7.291AsnLeu: 7.291 ± 0.805
1.411AsnMet: 1.411 ± 0.464
6.35AsnAsn: 6.35 ± 0.889
3.057AsnPro: 3.057 ± 0.847
3.293AsnGln: 3.293 ± 0.69
3.057AsnArg: 3.057 ± 1.1
2.587AsnSer: 2.587 ± 0.499
4.233AsnThr: 4.233 ± 0.752
2.822AsnVal: 2.822 ± 0.747
1.646AsnTrp: 1.646 ± 0.439
4.233AsnTyr: 4.233 ± 0.747
0.0AsnXaa: 0.0 ± 0.0
Pro
0.941ProAla: 0.941 ± 0.303
0.0ProCys: 0.0 ± 0.0
3.528ProAsp: 3.528 ± 0.885
2.117ProGlu: 2.117 ± 0.574
1.176ProPhe: 1.176 ± 0.813
0.706ProGly: 0.706 ± 0.709
1.176ProHis: 1.176 ± 0.317
2.587ProIle: 2.587 ± 0.663
3.293ProLys: 3.293 ± 0.469
3.763ProLeu: 3.763 ± 0.845
0.47ProMet: 0.47 ± 0.289
3.528ProAsn: 3.528 ± 0.824
1.176ProPro: 1.176 ± 0.421
1.646ProGln: 1.646 ± 0.509
0.941ProArg: 0.941 ± 0.456
3.998ProSer: 3.998 ± 0.586
2.822ProThr: 2.822 ± 1.062
1.411ProVal: 1.411 ± 0.44
0.706ProTrp: 0.706 ± 0.335
2.352ProTyr: 2.352 ± 0.42
0.0ProXaa: 0.0 ± 0.0
Gln
1.411GlnAla: 1.411 ± 0.516
0.706GlnCys: 0.706 ± 0.335
2.117GlnAsp: 2.117 ± 0.67
1.646GlnGlu: 1.646 ± 0.462
1.411GlnPhe: 1.411 ± 0.56
1.881GlnGly: 1.881 ± 0.446
1.411GlnHis: 1.411 ± 0.837
3.057GlnIle: 3.057 ± 0.799
2.352GlnLys: 2.352 ± 0.493
3.528GlnLeu: 3.528 ± 1.282
0.47GlnMet: 0.47 ± 0.452
2.587GlnAsn: 2.587 ± 1.072
0.47GlnPro: 0.47 ± 0.226
0.706GlnGln: 0.706 ± 0.395
2.587GlnArg: 2.587 ± 0.694
1.881GlnSer: 1.881 ± 0.522
2.822GlnThr: 2.822 ± 0.57
1.646GlnVal: 1.646 ± 0.596
0.706GlnTrp: 0.706 ± 0.329
1.411GlnTyr: 1.411 ± 0.303
0.0GlnXaa: 0.0 ± 0.0
Arg
2.587ArgAla: 2.587 ± 0.645
0.941ArgCys: 0.941 ± 0.452
2.117ArgAsp: 2.117 ± 0.965
2.587ArgGlu: 2.587 ± 0.736
2.352ArgPhe: 2.352 ± 0.436
1.881ArgGly: 1.881 ± 0.636
1.646ArgHis: 1.646 ± 0.868
1.881ArgIle: 1.881 ± 0.414
2.117ArgLys: 2.117 ± 0.802
3.293ArgLeu: 3.293 ± 0.696
1.176ArgMet: 1.176 ± 0.928
3.293ArgAsn: 3.293 ± 0.861
1.646ArgPro: 1.646 ± 0.482
1.176ArgGln: 1.176 ± 0.376
0.706ArgArg: 0.706 ± 0.355
5.174ArgSer: 5.174 ± 0.95
2.822ArgThr: 2.822 ± 0.464
2.117ArgVal: 2.117 ± 0.706
0.706ArgTrp: 0.706 ± 0.394
1.881ArgTyr: 1.881 ± 0.76
0.0ArgXaa: 0.0 ± 0.0
Ser
2.587SerAla: 2.587 ± 0.71
2.587SerCys: 2.587 ± 0.656
5.88SerAsp: 5.88 ± 1.109
3.293SerGlu: 3.293 ± 1.323
2.117SerPhe: 2.117 ± 0.522
4.233SerGly: 4.233 ± 1.01
2.587SerHis: 2.587 ± 0.669
7.526SerIle: 7.526 ± 1.632
3.528SerLys: 3.528 ± 1.177
7.761SerLeu: 7.761 ± 1.163
1.646SerMet: 1.646 ± 0.65
3.528SerAsn: 3.528 ± 0.938
2.352SerPro: 2.352 ± 0.501
3.057SerGln: 3.057 ± 0.46
4.468SerArg: 4.468 ± 1.014
7.526SerSer: 7.526 ± 3.428
4.468SerThr: 4.468 ± 1.052
3.057SerVal: 3.057 ± 0.957
1.646SerTrp: 1.646 ± 0.515
4.468SerTyr: 4.468 ± 0.683
0.0SerXaa: 0.0 ± 0.0
Thr
0.941ThrAla: 0.941 ± 0.66
1.411ThrCys: 1.411 ± 0.679
3.528ThrAsp: 3.528 ± 0.797
2.117ThrGlu: 2.117 ± 0.713
2.352ThrPhe: 2.352 ± 1.518
3.057ThrGly: 3.057 ± 0.56
2.352ThrHis: 2.352 ± 0.975
5.174ThrIle: 5.174 ± 1.309
4.468ThrLys: 4.468 ± 1.245
4.704ThrLeu: 4.704 ± 0.774
0.941ThrMet: 0.941 ± 0.28
3.293ThrAsn: 3.293 ± 1.219
1.646ThrPro: 1.646 ± 0.422
1.176ThrGln: 1.176 ± 0.726
2.822ThrArg: 2.822 ± 1.202
4.939ThrSer: 4.939 ± 0.852
3.763ThrThr: 3.763 ± 0.666
3.293ThrVal: 3.293 ± 0.679
2.352ThrTrp: 2.352 ± 0.524
2.117ThrTyr: 2.117 ± 0.571
0.0ThrXaa: 0.0 ± 0.0
Val
1.176ValAla: 1.176 ± 0.493
0.706ValCys: 0.706 ± 0.329
3.998ValAsp: 3.998 ± 2.038
1.881ValGlu: 1.881 ± 0.537
1.881ValPhe: 1.881 ± 0.706
2.822ValGly: 2.822 ± 0.437
0.706ValHis: 0.706 ± 0.355
4.233ValIle: 4.233 ± 1.094
3.057ValLys: 3.057 ± 1.301
6.115ValLeu: 6.115 ± 1.077
1.881ValMet: 1.881 ± 0.634
5.174ValAsn: 5.174 ± 0.342
2.117ValPro: 2.117 ± 0.795
1.646ValGln: 1.646 ± 0.349
1.411ValArg: 1.411 ± 0.416
3.293ValSer: 3.293 ± 0.712
3.528ValThr: 3.528 ± 0.556
1.176ValVal: 1.176 ± 0.863
0.706ValTrp: 0.706 ± 0.242
1.646ValTyr: 1.646 ± 0.88
0.0ValXaa: 0.0 ± 0.0
Trp
0.47TrpAla: 0.47 ± 0.467
0.0TrpCys: 0.0 ± 0.0
0.47TrpAsp: 0.47 ± 0.226
0.706TrpGlu: 0.706 ± 0.498
0.941TrpPhe: 0.941 ± 0.56
1.411TrpGly: 1.411 ± 0.699
0.235TrpHis: 0.235 ± 0.14
1.176TrpIle: 1.176 ± 0.651
1.881TrpLys: 1.881 ± 0.388
1.176TrpLeu: 1.176 ± 0.594
0.941TrpMet: 0.941 ± 0.49
1.176TrpAsn: 1.176 ± 0.573
0.706TrpPro: 0.706 ± 0.42
0.235TrpGln: 0.235 ± 0.14
0.47TrpArg: 0.47 ± 0.296
0.706TrpSer: 0.706 ± 0.242
1.176TrpThr: 1.176 ± 0.553
1.646TrpVal: 1.646 ± 0.531
0.235TrpTrp: 0.235 ± 0.288
0.941TrpTyr: 0.941 ± 0.256
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.941TyrAla: 0.941 ± 0.56
1.176TyrCys: 1.176 ± 0.52
3.763TyrAsp: 3.763 ± 0.778
1.881TyrGlu: 1.881 ± 0.846
3.057TyrPhe: 3.057 ± 0.561
1.881TyrGly: 1.881 ± 0.598
1.411TyrHis: 1.411 ± 0.731
3.057TyrIle: 3.057 ± 0.845
2.822TyrLys: 2.822 ± 0.522
4.704TyrLeu: 4.704 ± 1.154
0.706TyrMet: 0.706 ± 0.425
2.822TyrAsn: 2.822 ± 0.426
2.587TyrPro: 2.587 ± 0.948
1.411TyrGln: 1.411 ± 0.64
2.117TyrArg: 2.117 ± 0.9
3.528TyrSer: 3.528 ± 0.703
1.411TyrThr: 1.411 ± 0.658
3.293TyrVal: 3.293 ± 0.727
0.47TyrTrp: 0.47 ± 0.475
3.763TyrTyr: 3.763 ± 1.386
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (4253 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski